Boron neutron capture therapy device based on compact high-current proton RFQ accelerator

Abstract

The utility model relates to the technical field of tumor treatment, in particular to a boron neutron capture treatment device based on a compact high-current proton RFQ accelerator. Comprising a compact RFQ accelerator used for generating and accelerating a high-current proton beam, a lithium target station system used for converting the proton beam into an epithermal neutron beam, and a treatment room used for accurate placement of a patient, accurate positioning of a tumor and neutron irradiation. According to the treatment room, a patient is accurately positioned through the seven-degree-of-freedom cantilever robot treatment chair system or the seven-degree-of-freedom cantilever robot treatment bed system, and the tumor of the patient is accurately positioned through the sliding rail CT image guiding system or the orthogonal X-ray image guiding system. Then, the tumor rich in the boron medicine in the body of the patient is precisely bombarded by an epithermal neutron beam to generate a boron neutron capture reaction, alpha particles and Li-7 particles are released to break DNA double chains of tumor cells, so that the tumor cells cannot be repaired and die thoroughly, the tumor is precisely killed, and tumor recurrence is effectively inhibited.

Description

Technical Field

[0001] The utility model relates to the technical field of tumor particle therapy, in particular to a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator. Background Art

[0002] At present, there are three types of treatment for malignant tumors: surgical treatment, chemotherapy and radiotherapy. Radiotherapy kills tumor cells through ionizing radiation, but it also causes certain damage to the surrounding normal tissues, which can easily cause radiotherapy toxicity and side effects. The long-term effects of radiotherapy are especially important for pediatric patients. Once irreversible damage occurs during the treatment process, it will affect the growth and development of children and their quality of life in adulthood. Therefore, improving the accuracy of tumor radiotherapy, reducing damage to normal tissues, and improving the quality of life of patients have been the development trend of radiotherapy in recent years. Among all patients with malignant tumors, 70%-80% are suitable for radiotherapy. According to statistics from the World Health Organization, the current cure rate of tumors has reached 45%, and radiotherapy contributes 22% of it. This shows the status and role of radiotherapy in tumor treatment.

[0003] Boron neutron capture therapy (BNCT) is a radiotherapy method, mainly used to treat invasive, multiple, recurrent, radiation-resistant, and extremely malignant tumors that cannot be well treated by surgery and chemoradiotherapy. So far, there have been more than 2,000 related clinical cases worldwide, and it has been proven that this method has a good effect in treating various solid tumors such as gliomas, recurrent head and neck tumors, meningiomas, malignant melanomas, and liver metastases. At the same time, with the development of clinical research on other types of tumors and the development of new boron drugs worldwide, the indications of this method will continue to increase, and it is very likely to become an ideal tumor treatment method in the future. In addition to tumors, this method can also be extended to other diseases such as Alzheimer's.

[0004] At present, there are two types of technologies that can achieve boron neutron therapy in the world. One is to use a neutron source based on a nuclear reactor, and the other is to generate neutrons by bombarding the target material with a charged particle beam generated by an accelerator. The accelerator-based technology mainly includes three technical routes: electrostatic accelerator, cyclotron accelerator and linear accelerator. RFQ accelerator is a commonly used linear accelerator.

[0005] The proton beam provided by the cyclotron has the characteristics of high energy and low current intensity, resulting in high neutron energy produced by proton target shooting. The moderator is huge in size and the epithermal neutron flux produced is relatively low, resulting in long treatment time, high fast neutron and thermal neutron components, and high radiation level in the treatment room.

[0006] The proton beam provided by an electrostatic accelerator or RFQ accelerator has the characteristics of low energy and high current intensity. Therefore, the neutron energy produced by proton targeting is low, the neutron target station is small in size, and the radiation level in the treatment room is low, which is more suitable for clinical treatment.

[0007] Equipment using electrostatic accelerator technology is prone to high-voltage sparks, which can cause unstable operation of the equipment and damage to electronic equipment at the high-voltage end. In addition, the electrostatic accelerator generates high levels of bremsstrahlung during operation, which increases the difficulty of shielding the equipment. In addition, the divergence of high-current beams in the electrostatic accelerator tube can cause beam collapse, which can add new difficulties to accelerator debugging.

[0008] Conventional proton RFQ accelerators are long and have relatively high construction costs. When the accelerator is running, the power loss is high and the electricity consumption is large, making its overall cost relatively high. Utility Model Content

[0009] The purpose of the utility model is to provide a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator, aiming to provide a patient positioning method for multiple treatment postures, a precise image-guided tumor positioning method, and a fast and accurate treatment plan formulation method, so as to achieve more precise and efficient treatment of malignant tumors, and at the same time fully compress the space required for the accelerator and better reduce costs.

[0010] To achieve the above-mentioned purpose, the utility model provides a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator, comprising a compact RFQ accelerator for generating and accelerating a high-current proton beam, a lithium target station system for converting the proton beam into an epithermal neutron beam, and a treatment room for precise patient positioning and tumor positioning and neutron irradiation; the lithium target station system is provided with two, one end of which is connected to the proton accelerator and the other end is connected to the treatment room system; the treatment room system comprises two, which are divided into a first treatment room and a second treatment room. treatment room, each treatment room is uniquely connected to the lithium target station system; the compact RFQ accelerator can generate a high-intensity proton beam; the lithium target station system can generate a neutron beam after the proton beam bombards the lithium target station, and slow down and shape the neutron beam to generate epithermal neutrons that can be used for treatment; the treatment room adopts a seven-degree-of-freedom cantilever robot treatment bed system or a seven-degree-of-freedom cantilever robot treatment chair system to accurately position the patient, and adopts a slide rail CT image guidance system or an orthogonal X-ray image guidance system to achieve accurate positioning of the patient's tumor.

[0011] The proton beam energy is greater than 2.3 MeV, and the average current is greater than 10 mA.

[0012] The compact RFQ accelerator includes a high-current ECR ion source, a low-energy beam transmission line, a compact RFQ cavity and a high-energy beam transmission line.

[0013] The high-current ECR ion source is used to generate a direct current, high-current, low-energy proton beam;

[0014] The low-energy beam transmission line is used to transmit a low-energy proton beam and inject it into the compact RFQ cavity;

[0015] The compact RFQ cavity is used to accelerate the proton beam from low energy to high energy, ensure the beam quality, and control the beam loss;

[0016] The high-energy beam transmission line is used to transmit a high-energy proton beam to the front end of the lithium target station system.

[0017] Wherein, the length of the compact RFQ chamber is not more than 3 meters.

[0018] Among them, the first treatment room includes a seven-degree-of-freedom cantilever robot treatment bed system and a slide rail CT image guidance system. The seven-degree-of-freedom cantilever robot treatment bed system is used to load patients and adjust their positions. The slide rail CT image guidance system includes a slide rail unit set on the ground and a CT device set on the slide rail unit. When the CT device is working, it moves from the parking position to the working position through the slide rail unit; when the CT device completes its work, it moves back to the parking position through the slide rail unit. The slide rail CT image guidance system is used to accurately locate the patient's tumor, and then adjust the patient's treatment position according to the image registration result, and the slide rail motion unit and robot motion unit of the seven-degree-of-freedom cantilever robot treatment bed system move the patient to the final treatment position.

[0019] The slide rail CT image guidance system further comprises a CT radiation shielding door, and the CT radiation shielding door is used for shielding radiation when the CT device is in a parking position when not in operation.

[0020] Among them, the second treatment room includes a seven-degree-of-freedom cantilever robot treatment chair system and an orthogonal X-ray image guidance system. The seven-degree-of-freedom cantilever robot treatment chair system is used for patients to sit and adjust their positions. The orthogonal X-ray image guidance system is used to accurately locate the patient's tumor, and then adjust it according to the image registration result. The slide motion unit and robot motion unit of the seven-degree-of-freedom cantilever robot treatment chair system move the patient to the final treatment position.

[0021] Wherein, the orthogonal X-ray image guidance system further comprises an X-ray radiation shielding door, and the X-ray radiation shielding door is used for shielding the radiation of the orthogonal X-rays when not in operation.

[0022] Among them, the boron neutron capture therapy device based on a compact high-current proton RFQ accelerator also includes a treatment planning system, which is dedicated to BNCT and implements the formulation of patient treatment plans based on GPU fast dose calculation and AI technology.

[0023] Wherein, the treatment planning system includes a machine data management unit, a patient data management unit, a patient image processing unit, a plan formulation unit, a dose calculation engine, a plan evaluation unit, a plan output unit and a quality verification unit;

[0024] The machine data management unit is used to record and manage treatment beam parameters and treatment device parameters;

[0025] The patient data management unit is used to record and manage the treatment information and imaging information of the treated patient. The treatment information mainly includes the patient's name, age, head portrait, tumor location and size. The imaging information management is mainly to achieve management between different imaging groups.

[0026] The patient image processing unit is used for delineating the patient's organs, including a processing function for adding and deleting a treatment bed, and a fusion correction processing function for multiple patient images, wherein the image data includes the patient's PET-CT image, MR positioning image, CT positioning image, etc.;

[0027] The planning unit is used to outline the patient's treatment target area based on the patient's image data to ensure the killing of tumor cells and avoid or reduce the dose irradiation to normal tissues and organs at risk;

[0028] The dose calculation engine is used to calculate the radiation dose distribution required for the patient according to the plan prepared by the medical physicist;

[0029] The plan evaluation unit is used to evaluate the expected treatment effect of the formulated plan and determine whether the plan can meet the clinical treatment goals;

[0030] The plan output unit is used to generate a practical and executable treatment plan from the evaluated and confirmed plan;

[0031] The quality verification unit is used to verify the final executability of the plan and the compliance of the dose distribution.

[0032] The utility model discloses a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator. The compact proton RFQ accelerator with a length of no more than 3 meters is used to induce a proton beam with an energy greater than 2.3 MeV and an average current greater than 10 mA. The proton beam is transported to one or more target station systems through a high-energy beam transmission line. The target station adopts lithium target technology. After the proton beam bombards the lithium target station, a neutron beam is generated, and the neutron beam is slowed down and shaped to generate an epithermal neutron beam that can be used for treatment. During treatment, the patient is accurately positioned using a seven-degree-of-freedom cantilever robot treatment bed system or a seven-degree-of-freedom cantilever robot treatment chair system, and the patient's tumor is accurately located using a slide rail CT image guidance system or an orthogonal X-ray image guidance system. The boron drug-rich tumor in the patient's body is then accurately bombarded with an epithermal neutron beam, causing a boron neutron capture reaction and releasing alpha particles and lithium-7 particles, two heavy ion rays with a range of only about 10 microns, which break the double-stranded DNA of the tumor cells, making them irreparable and completely dead, thereby accurately killing the tumor and effectively inhibiting tumor recurrence. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the technical solutions in the embodiments of the utility model or the prior art, the drawings required for the embodiments or the prior art description are briefly introduced below. Obviously, the specific embodiments described here are only used to explain the utility model, but not to limit the utility model. It should also be noted that, for the convenience of description, only the parts related to the utility model are shown in the drawings, not all of them.

[0034] Figure 1 It is a structural diagram of a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator according to the first embodiment of the utility model.

[0035] Figure 2 It is a structural block diagram of a compact RFQ accelerator and a lithium target station according to the first embodiment of the utility model.

[0036] Figure 3 It is a structural side view of the first treatment room of the first embodiment of the utility model.

[0037] Figure 4 It is a top view of the structure of the second treatment room of the first embodiment of the utility model.

[0038] Figure 5 It is a logic diagram of the treatment planning system of the first embodiment of the utility model.

[0039] Compact RFQ accelerator 101, lithium target station 102, first treatment room 103, second treatment room 104, high-current ECR ion source 105, low-energy beam transmission line 106, compact RFQ cavity 107, high-energy beam transmission line 108, seven-degree-of-freedom cantilever robot treatment bed system 109, slide rail CT image guidance system 110, CT equipment 111, slide rail unit 112, CT radiation shielding door 113, orthogonal X-ray image guidance system 114, seven-degree-of-freedom cantilever robot treatment chair system 115, treatment planning system 116, machine data management unit 117, patient data management unit 118, patient image processing unit 119, dose calculation engine 120, plan formulation unit 121, plan evaluation unit 122, plan output unit 123, quality verification unit 124, X-ray radiation shielding door 125. DETAILED DESCRIPTION

[0040] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0041] See also Figure 1 to Figure 4The utility model provides a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator, comprising a compact RFQ accelerator 101, two lithium target stations 102, a first treatment room 103 and a second treatment room 104, the two lithium target stations 102 are connected to the compact RFQ accelerator 101, the first treatment room 103 and the second treatment room 104 are respectively connected to the two lithium target stations 102; the compact RFQ accelerator 101 is used to generate and accelerate a high-current proton beam; the lithium target station 102 adopts lithium target technology to bombard the proton beam with a first target station 103 and a second treatment room 104; After striking the lithium target station, a neutron beam is generated, which is slowed down and shaped to generate epithermal neutrons that can be used for treatment. The first treatment room 103 uses a slide rail CT image guidance system 110 to accurately locate the patient's tumor, and uses a seven-degree-of-freedom cantilever robot treatment bed system 109 to accurately position the patient, and then uses an epithermal neutron beam to perform neutron treatment on the patient; the second treatment room 104 uses an X-ray image guidance system 114 to perform image-guided positioning on the patient, and uses a seven-degree-of-freedom cantilever robot treatment chair system 115 to accurately position the patient, and then uses epithermal neutrons to perform neutron treatment on the patient. In this embodiment, the BNCT treatment device based on a compact high-current proton RFQ accelerator uses a compact proton RFQ accelerator with a length of no more than 3 meters to extract a proton beam with an energy greater than 2.3 MeV and an average current greater than 10 mA, and transports the proton beam to one or more target station systems through a high-energy beam transmission line 108. The target station uses lithium target technology. After the proton beam bombards the lithium target station 102, a neutron beam is generated, which is slowed down and shaped to produce an epithermal neutron beam that can be used for treatment. During treatment, the patient is accurately positioned in the treatment room by means of a seven-degree-of-freedom cantilever robot treatment chair system 115 or a seven-degree-of-freedom cantilever robot treatment bed system 109, and the patient's tumor is accurately located by means of a slide rail CT image guidance system 110 or an orthogonal X-ray image guidance system 114. The boron drug-rich tumor in the patient's body is then accurately bombarded with an epithermal neutron beam, causing a boron neutron capture reaction and releasing alpha particles and lithium 7 particles, two heavy ion rays with a range of only about 10 microns, which break the double-stranded DNA of the tumor cells, making them irreparable and completely dead, thereby accurately killing the tumor and effectively inhibiting tumor recurrence.

[0042] The compact RFQ accelerator 101 includes a high-current ECR ion source 105, a low-energy beam transmission line 106, a compact RFQ cavity 107 and a high-energy beam transmission line 108. The high-current ECR ion source 105 is used to generate protons; the low-energy beam transmission line 106 is used to transmit a low-energy particle beam and inject it into the compact RFQ cavity; the compact RFQ cavity 107 is used to accelerate the proton beam from low energy to high energy, ensure the beam quality, and control the beam loss; the high-energy beam transmission line 108 is used to transmit a high-energy particle beam to the lithium target station system. The ion source adopts an ECR electron cyclotron resonance ion source with a GHz microwave frequency. After the proton beam is extracted by high voltage, it is injected into the entrance of the compact RFQ cavity through the low-energy beam transmission line 106. In the compact RFQ cavity with a length of no more than 3 meters, the beam is captured, focused, bunched and accelerated by the radio frequency electromagnetic field to generate a proton beam with an energy greater than 2.3 MeV and an average current greater than 10 mA. The beam is transported to one or more lithium target stations 102 through the high-energy beam transmission line 108.

[0043] The first treatment room 103 includes a seven-degree-of-freedom cantilever robot treatment bed system 109 and a slide rail CT image guidance system 110. The seven-degree-of-freedom cantilever robot treatment bed system 109 is used to load patients and adjust their positions. The slide rail CT image guidance system 110 includes a slide rail unit 112 arranged on the ground and a CT device 111 arranged on the slide rail unit 112. When the CT device 111 is working, it moves from the parking position to the working position through the slide rail unit 112; when the CT device 111 completes its work, it moves back to the parking position through the slide rail unit 112. The slide rail CT image guidance system 110 is used to accurately locate the patient's tumor, and then adjust the patient's treatment position according to the image registration result, and the slide rail motion unit and the robot motion unit of the seven-degree-of-freedom cantilever robot treatment bed system 109 move the patient to the final treatment position.

[0044] The slide rail CT image guidance system also includes a CT radiation shielding door 113, which is used to shield the radiation of the CT device 111 when it is in the parking position when not in operation. In the treatment room, due to the high neutron and gamma ray dose levels, in order to avoid radiation damage to the CT device 111, it is necessary to perform radiation shielding on the CT device 111 when it is in the parking position when not in operation. When the CT device 111 is not in use, it is moved to the rear of the CT radiation shielding door 113, i.e., the parking position; when image guidance positioning is required, the CT radiation shielding door 113 is opened, and the CT is moved to the working position through the slide rail for imaging. After the image guidance positioning is completed, the CT moves back to the parking position of the radiation shielding area, and the CT radiation shielding door 113 is closed.

[0045] The second treatment room 104 includes an orthogonal X-ray image guidance system 114 and a seven-degree-of-freedom cantilever robot treatment chair system 115. The seven-degree-of-freedom cantilever robot treatment chair system 115 is used for patients to sit and adjust their positions. The orthogonal X-ray image guidance system 114 is used to perform image-guided positioning on patients. After that, the actual treatment position is adjusted according to the image registration result, and the slide motion unit and the robot motion unit move the patient to the final treatment position. After the patient enters the treatment room, the treatment chair is placed in the patient's position for the patient to sit on the stage by the slide motion unit and the robot motion unit; after the patient sits on the treatment chair, the patient is fixed on the treatment chair by a fixing device, and the slide motion unit and the robot motion unit move the patient to the imaging position, and the orthogonal X-ray imaging system 114 performs image-guided positioning on the patient; then, according to the image registration result, the actual treatment position is adjusted, and the slide motion system and the robot motion system move the patient to the final treatment position for treatment.

[0046] The orthogonal X-ray image guidance system also includes an X-ray radiation shielding door 125, which is used to shield the X-ray system 114 from radiation when it is not in operation. In the treatment room, due to the high neutron and gamma ray dose levels, in order to avoid radiation damage to the X-ray system 114, it is necessary to shield the X-ray system 114 from radiation when it is not in operation. When the X-ray system 114 is not in use, the X-ray radiation shielding door 125 is closed; when image guidance positioning is required, the X-ray radiation shielding door 125 is opened, and the seven-degree-of-freedom cantilever robot treatment chair system 115 is used to position the patient to the imaging position and perform imaging. After the image guidance positioning is completed, the seven-degree-of-freedom cantilever robot treatment chair system 115 is moved out and the X-ray radiation shielding door 125 is closed. The boron neutron capture therapy device based on a compact high-current proton RFQ accelerator also includes a treatment planning system 116, which is dedicated to BNCT and implements the formulation of patient treatment plans based on GPU fast dose calculation and AI technology.

[0047] The treatment planning system 116 includes a machine data management unit 117, a patient data management unit 118, a patient image processing unit 119, a dose calculation engine 120, a plan formulation unit 121, a plan evaluation unit 122, a plan output unit 123 and a quality verification unit 124;

[0048] The machine data management unit 117 is responsible for recording and managing the treatment beam parameters and treatment device parameters. These parameters are the basis for accurate irradiation and directly affect the treatment effect and patient safety. Therefore, effective management of beam parameters and treatment device parameters is crucial.

[0049] The patient data management unit 118 is responsible for recording and managing the treatment information and imaging information of the treated patients. The treatment information includes the patient's name, age, head portrait, tumor location and size, etc. The imaging information mainly includes the patient's PET-CT image, MR positioning image, CT positioning image, etc. This information provides an important basis for subsequent planning and evaluation.

[0050] The patient image processing unit 119 is responsible for delineating the patient's organs and has the processing function of adding and deleting the treatment bed. In addition, it is also responsible for fusing and correcting the patient's multiple images to ensure the accuracy of the treatment plan.

[0051] The dose calculation engine 120 is the core part that automatically outlines the patient's treatment target area based on the patient's image data. It ensures the killing effect on tumor cells while minimizing the dose irradiation to normal tissues and endangered organs, thereby improving the safety and effectiveness of treatment.

[0052] The planning unit 121 is responsible for calculating the radiation dose distribution required for the patient according to the plan prepared by the medical physicist. This process needs to comprehensively consider multiple factors such as the patient's condition, tumor characteristics, and treatment equipment to achieve personalized treatment.

[0053] The plan evaluation unit 122 is responsible for evaluating the expected treatment effect of the formulated plan and determining whether the plan can meet the clinical treatment goals. This link helps to discover potential problems, adjust the treatment plan in advance, and ensure that the treatment proceeds smoothly.

[0054] The plan output unit 123 is responsible for generating an actually executable treatment plan from the evaluated and confirmed plan. This process needs to ensure the feasibility of the plan and the conformity of the dose distribution to ensure the safety and effectiveness of the treatment.

[0055] The quality verification unit 124 is responsible for quality control and verification of the entire treatment plan generation process, and ensures the quality and safety of the entire treatment process by monitoring the plan formulation, evaluation and execution.

[0056] In summary, the treatment planning system 116 realizes the rapid and accurate formulation and evaluation of personalized treatment plans for patients through the coordinated work of various subsystems, which helps to improve treatment effects, reduce adverse reactions, and provide patients with safer and more efficient radiotherapy.

[0057] What is disclosed above is only a preferred embodiment of the present invention, and it certainly cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that all or part of the processes of the above embodiment and equivalent changes made according to the claims of the present invention still fall within the scope covered by the utility model.

Claims

1. A boron neutron capture therapy device based on a compact high-current proton RFQ accelerator, comprising a compact RFQ accelerator for generating and accelerating a high-current proton beam, a lithium target station system for converting the proton beam into an epithermal neutron beam, and a treatment room for precise patient positioning and tumor positioning and neutron irradiation; the lithium target station system is provided with two, one end of which is connected to the compact RFQ accelerator and the other end is connected to the treatment room; the treatment room comprises two, which are divided into a first treatment room and a second treatment room, and each treatment room is uniquely connected to the lithium target station system; characterized in that: The compact RFQ accelerator can generate a high-intensity proton beam; the lithium target station system can generate a neutron beam after the proton beam bombards the lithium target station, and slow down and shape the neutron beam to generate epithermal neutrons that can be used for treatment; the treatment room adopts a seven-degree-of-freedom cantilever robot treatment bed system or a seven-degree-of-freedom cantilever robot treatment chair system to accurately position the patient, and adopts a slide rail CT image guidance system or an orthogonal X-ray image guidance system to achieve accurate positioning of the patient's tumor.

2. A boron neutron capture therapy device based on a compact high-current proton RFQ accelerator as claimed in claim 1, characterized in that: The proton beam energy is greater than 2.3 MeV, and the average current is greater than 10 mA.

3. A boron neutron capture therapy device based on a compact high-current proton RFQ accelerator as claimed in claim 1, characterized in that: The compact RFQ accelerator comprises a high-current ECR ion source, a low-energy beam transmission line, a compact RFQ cavity and a high-energy beam transmission line; The high-current ECR ion source is used to generate a direct current, high-current, low-energy proton beam; The low-energy beam transmission line is used to transmit a low-energy proton beam and inject it into the compact RFQ cavity; The compact RFQ cavity is used to accelerate the proton beam from low energy to high energy, ensure the beam quality, and control the beam loss; The high-energy beam transmission line is used to transmit a high-energy proton beam to the front end of the lithium target station system.

4. A boron neutron capture therapy device based on a compact high-current proton RFQ accelerator as claimed in claim 3, characterized in that: The length of the compact RFQ chamber is no more than 3 meters.

5. The boron neutron capture therapy device based on a compact high-current proton RFQ accelerator according to claim 1, characterized in that: The first treatment room includes a seven-degree-of-freedom cantilever robot treatment bed system and a slide rail CT image guidance system. The seven-degree-of-freedom cantilever robot treatment bed system is used for loading and adjusting the position of patients. The slide rail CT image guidance system includes a slide rail unit arranged on the ground and a CT device arranged on the slide rail unit. When the CT device is working, it moves from a parking position to a working position through the slide rail unit; when the CT device completes its work, it moves back to the parking position through the slide rail unit. The slide rail CT image guidance system is used to accurately locate the patient's tumor, and then adjust the patient's treatment position according to the image registration result. The slide rail motion unit and the robot motion unit of the seven-degree-of-freedom cantilever robot treatment bed system move the patient to the final treatment position.

6. The boron neutron capture therapy device based on a compact high-current proton RFQ accelerator according to claim 1, characterized in that: The slide rail CT image guidance system further comprises a CT radiation shielding door, which is used for shielding radiation of the CT device when it is in a parking position when not in operation.

7. The boron neutron capture therapy device based on a compact high-current proton RFQ accelerator according to claim 1, characterized in that: The second treatment room includes a seven-degree-of-freedom cantilever robot treatment chair system and an orthogonal X-ray image guidance system. The seven-degree-of-freedom cantilever robot treatment chair system is used for patients to sit and adjust their positions. The orthogonal X-ray image guidance system is used to accurately locate the patient's tumor and then adjust the patient's treatment position based on the image registration results. The patient is moved to the final treatment position by the slide motion unit and robot motion unit of the seven-degree-of-freedom cantilever robot treatment chair system.

8. The boron neutron capture therapy device based on a compact high-current proton RFQ accelerator according to claim 1, characterized in that: The orthogonal X-ray image guidance system further comprises an X-ray radiation shielding door, wherein the X-ray radiation shielding door is used for shielding the orthogonal X-ray radiation when not in operation.

9. The boron neutron capture therapy device based on a compact high-current proton RFQ accelerator according to claim 1, characterized in that: The boron neutron capture therapy device based on a compact high-current proton RFQ accelerator also includes a treatment planning system, which is dedicated to BNCT and implements the formulation of patient treatment plans based on GPU fast dose calculation and AI technology.

10. A boron neutron capture therapy device based on a compact high-current proton RFQ accelerator as claimed in claim 9, characterized in that: The treatment planning system includes a machine data management unit, a patient data management unit, a patient image processing unit, a plan formulation unit, a dose calculation engine, a plan evaluation unit, a plan output unit and a quality verification unit; The machine data management unit is used to record and manage treatment beam parameters and treatment device parameters; The patient data management unit is used to record and manage the treatment information and imaging information of the treated patient. The treatment information mainly includes the patient's name, age, head portrait, tumor location and size. The imaging information management is mainly to achieve management between different imaging groups. The patient image processing unit is used for delineating the patient's organs, including a processing function for adding and deleting a treatment bed, and a fusion correction processing function for multiple patient images, wherein the image data includes the patient's PET-CT image, MR positioning image, and CT positioning image; The planning unit is used to outline the patient's treatment target area based on the patient's image data to ensure the killing of tumor cells and avoid or reduce the dose irradiation to normal tissues and organs at risk; The dose calculation engine is used to calculate the radiation dose distribution required for the patient according to the plan prepared by the medical physicist; The plan evaluation unit is used to evaluate the expected treatment effect of the formulated plan and determine whether the plan can meet the clinical treatment goals; The plan output unit is used to generate a practical and executable treatment plan from the evaluated and confirmed plan; The quality verification unit is used to verify the final executability of the plan and the compliance of the dose distribution.

Images