Reagent mixing device

Abstract

The utility model discloses a reagent mixing device, which belongs to the technical field of biological experiment tools and comprises a base, a driving component, a mixing seat and a kit, the driving component is mounted on the base, and the mixing seat is mounted at the output end of the driving component; a fixing structure is arranged on the uniform mixing seat, and the kit is provided with a clamping groove matched with the fixing structure; the kit comprises a kit body, a cover body and an elastic assembly, a plurality of containing cavities are formed in the kit body, and the cover body is installed on the kit body and used for sealing the containing cavities; the elastic assembly is installed on the bottom wall of the containing cavity, and the telescopic direction of the elastic assembly is consistent with the depth direction of the containing cavity. The driving assembly is used for turning over and uniformly mixing reagents in the kit; existing reagent tubes have various types of lengths and capacities, the reagent tubes with different lengths are placed in the containing cavity, the bottoms of the reagent tubes are arranged on the elastic assembly, the tops of the reagent tubes are sealed by the cover body, and the reagent tubes with different lengths can be uniformly mixed at the same time.

Description

Technical Field

[0001] The utility model belongs to the technical field of biological experiment tools, in particular to a reagent mixing device. Background Art

[0002] Tumbling and mixing is a common operation process in chemical and medical laboratory production processes, such as nucleic acid extraction and the preparation of various liquid reagents. For this reason, people have designed tumbling and mixing devices for reagent mixing, and the mixing speed and time of the tumbling and mixing devices are usually adjustable.

[0003] When performing large-scale nucleic acid extraction, many 1.5mL or 0.5mL reagent tubes are used. When flipping and mixing, the reagent tubes need to be taken out manually and placed in the corresponding equipment fixtures, which is inefficient and not suitable for batch operations. Moreover, reagent tubes of different lengths have different capacities. Reagent tubes of different lengths need to be placed in corresponding reagent kits for mixing, and multiple reagent kits need to be produced. Therefore, the adaptability of existing reagent kits is low. Summary of the invention

[0004] The utility model aims to improve the problems that the existing tumbling mixing device cannot perform large-scale mixing and the reagent kit has low adaptability, and provides a reagent mixing device.

[0005] The technical solutions to achieve the above objectives include the following:

[0006] The reagent mixing device comprises: a base, a driving component, a mixing seat, and a reagent kit, wherein the driving component is installed on the base, and the mixing seat is installed at the output end of the driving component;

[0007] The test kit includes a box body, a cover body, and an elastic component. The box body has at least one accommodating cavity. The cover body is installed on the box body and is used to seal the accommodating cavity. The elastic component is installed on the bottom wall of the accommodating cavity, and the expansion and contraction direction of the elastic component is consistent with the depth direction of the accommodating cavity.

[0008] In one embodiment, the elastic component includes a spring and a support plate, the spring is arranged at the bottom of the accommodating cavity, and the support plate is installed on the spring;

[0009] The cover body has a sealing plug corresponding to the accommodating cavity, and the sealing plug is arranged above the supporting plate;

[0010] The support plate has at least two moving positions in the accommodating cavity. In the first moving position, the support plate is close to the bottom of the accommodating cavity, and the space of the accommodating cavity is increased; in the second moving position, the support plate is away from the bottom of the accommodating cavity, and the space of the accommodating cavity is reduced.

[0011] In one embodiment, the mixing seat has a fixing structure, and the reagent box has a slot that cooperates with the fixing structure.

[0012] In one embodiment, the fixing structure includes at least two buckles, both of which are mounted on the mixing seat, and the two buckles are arranged opposite to each other, and the number of the slots corresponds to the number of the buckles;

[0013] The buckle is in a barb-shaped structure, the slot is arranged on the side wall of the box body, and the buckle cooperates with the slot.

[0014] In one embodiment, the fixing structure includes at least two limiting columns, the first ends of the limiting columns are mounted on the mixing seat, the slot is arranged on the box body, and the slot runs through from one end of the box body to the other end of the box body;

[0015] The second end of the limiting column is passed through the slot, so that the second end of the limiting column abuts against the upper end surface of the box body, and the lower end surface of the box body abuts against the mixing seat.

[0016] In one embodiment, the limiting column includes at least three elastic rods, which are arranged in a matrix, with a gap between two adjacent elastic rods, and the diameter of the first end of the elastic rod is greater than the diameter of the second end of the elastic rod.

[0017] In one embodiment, the elastic rod includes a supporting portion and an abutting portion, the abutting portion is mounted on the supporting portion, and a cross-sectional area of ​​the abutting portion is larger than a cross-sectional area of ​​the supporting portion.

[0018] In one embodiment, the elastic rod is in a barbed hook structure.

[0019] In one embodiment, the reagent mixing device further comprises an elastic band, both ends of which are connected to the mixing seat, and the reagent box is arranged between the inner wall of the elastic band and the outer side of the mixing seat.

[0020] In one embodiment, the driving assembly includes a motor, a rotating shaft, and a bearing, and the reagent mixing device further includes a housing and a support member, wherein the housing is mounted on a first end of the base, and the support member is mounted on a second end of the base, and the housing and the support member are arranged opposite to each other;

[0021] The motor is arranged in the shell, the mixing seat is sleeved on the outside of the rotating shaft, the first end of the rotating shaft is installed on the output end of the motor, the bearing is sleeved on the outside of the second end of the rotating shaft, and the bearing is arranged on the support member, and the second end of the rotating shaft is rotatably matched with the support member through the bearing.

[0022] The technical solution provided by the utility model has the following advantages and effects:

[0023] The top of the reagent tube is squeezed by the cover body, so that the bottom of the reagent tube squeezes the elastic component. The forces of squeezing the elastic component by reagent tubes of different lengths are different. The elastic component generates a reaction force, and the top of the reagent tube is always against the lower end surface of the cover body, so that reagent tubes of different types or lengths can be sealed by the cover body. Such a test kit can accommodate reagent tubes of different lengths or capacities, greatly improving the adaptability of the mixing device. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The accompanying drawings herein show specific examples of the technical solutions described in the present utility model, and together with the specific implementation methods constitute a part of the specification, and are used to explain the technical solutions, principles and effects of the present utility model.

[0025] Unless otherwise specified or defined, the same reference numerals in different drawings represent the same or similar technical features, and the same or similar technical features may also be represented by different reference numerals.

[0026] Figure 1 It is a schematic diagram of a reagent mixing device in one embodiment of the utility model;

[0027] Figure 2 is a cross-sectional view of a reagent mixing device in one embodiment of the utility model;

[0028] Figure 3 This is a schematic diagram of a mixing seat in an embodiment of the utility model. Figure 1 ;

[0029] Figure 4 This is a schematic diagram of a mixing seat in an embodiment of the utility model. Figure 2 ;

[0030] Figure 5 It is a schematic diagram of a limiting column in an embodiment of the utility model;

[0031] Figure 6 It is a cross-sectional view of a reagent box in one embodiment of the utility model Figure 1 ;

[0032] Figure 7 It is a cross-sectional view of a reagent box in one embodiment of the utility model Figure 2 ;

[0033] Description of reference numerals:

[0034] 100. Reagent mixing device; 1. Housing; 2. Base; 21. Support member; 3. Drive assembly; 31. Adjustment knob; 32. Switch; 33. Motor; 34. Rotating shaft; 35. Circuit board; 36. Bearing; 4. Mixing seat; 41. Fixing structure; 411. Buckle; 412. Limiting column; 4120. Elastic rod; 4121. Support portion; 4122. Abutment portion; 4123. Gap; 42. Elastic band; 5. Reagent box; 51. Box body; 511. Card slot; 512. Accommodating cavity; 52. Cover body; 521. Sealing plug; 53. Pin; 54. Elastic assembly; 541. Spring; 542. Support plate; 55. Reagent tube. DETAILED DESCRIPTION

[0035] In order to facilitate the understanding of the present invention, specific embodiments of the present invention will be described in more detail below with reference to the accompanying drawings.

[0036] Unless otherwise specified or defined, the "first, second..." used in this article is merely used to distinguish names and does not represent a specific quantity or order.

[0037] Unless specifically stated or defined otherwise, the term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0038] It should be noted that when a component is considered to be "fixed to" another component, it can be directly fixed to the other component or there can be a central component; when an component is considered to be "connected to" another component, it can be directly connected to the other component or there can be a central component at the same time; when an component is considered to be "installed on" another component, it can be directly installed on the other component or there can be a central component at the same time. When an component is considered to be "set on" another component, it can be directly set on the other component or there can be a central component at the same time.

[0039] The present invention provides a reagent mixing device 100, such as Figures 1 to 7As shown, it includes a base 2, a driving component 3, a mixing seat 4, and a reagent box 5. The driving component 3 is installed on the base 2, and the mixing seat 4 is installed at the output end of the driving component 3; the mixing seat 4 has a fixing structure 41, and the reagent box 5 has a card slot 511 that cooperates with the fixing structure 41; the reagent box 5 includes a box body 51, a cover body 52, and an elastic component 54. The box body 51 has a plurality of accommodating cavities 512. The cover body 52 is installed on the box body 51 and is used to seal the accommodating cavities 512; the elastic component 54 is installed on the bottom wall of the accommodating cavity 512, and the telescopic direction of the elastic component 54 is consistent with the depth direction of the accommodating cavity 512. Specifically, in the mixing operation, the driving component 3 is used to provide power and drive the reagent box 5 on the mixing seat 4 to rotate, so that the reagent in the reagent box 5 completes the flipping and mixing operation; the reagent is generally stored in a reagent tube 55, and the existing reagent tube 55 has a variety of lengths and capacities. Therefore, the reagent tubes 55 of different lengths are placed in the accommodating cavity 512, so that the bottom of the reagent tube 55 is set on the elastic component 54, and the top of the reagent tube 55 is sealed by the cover body 52. ​​Multiple accommodating cavities 512 are used to place multiple reagent tubes 55 to achieve large-scale reagent mixing operations. In actual operation, the cover 52 squeezes the top of the reagent tube 55, so that the bottom of the reagent tube 55 squeezes the elastic component 54. The strength of the reagent tubes 55 of different lengths squeezing the elastic component 54 is different. The elastic component 54 generates a reaction force, and the top of the reagent tube 55 always abuts against the lower end surface of the cover 52, so that the reagent tubes 55 of different lengths can be sealed by the cover 52. Such a reagent kit 5 can accommodate reagent tubes 55 of different lengths or capacities, greatly improving the adaptability of the mixing device 100. The reagent kit 5 rotates rapidly with the mixing seat 4 to achieve centrifugal mixing. In addition, the card slot 511 on the reagent kit 5 cooperates with the fixed structure 41, so that the reagent kit 5 is connected with the mixing seat 4, which is convenient for the assembly and disassembly of the reagent kit 5 and the mixing seat 4.

[0040] Preferably, Figure 6 and Figure 7As shown, the elastic component 54 includes a spring 541 and a support plate 542, the spring 541 is arranged at the bottom of the accommodating chamber 512, and the support plate 542 is installed on the spring 541; the cover body 52 has a sealing plug 521 corresponding to the accommodating chamber 512, and the sealing plug 521 is arranged above the support plate 542; the support plate 542 has at least two moving positions in the accommodating chamber 512, in the first moving position, the support plate 542 is close to the bottom of the accommodating chamber 512, and the space of the accommodating chamber 512 is increased; in the second moving position, the support plate 542 is away from the bottom of the accommodating chamber 512, and the space of the accommodating chamber 512 is reduced. Specifically, the support plate 542 is used to support the reagent tube 55, thereby improving the stability of the reagent tube 55 in the accommodating chamber 512; when the cover body 52 moves to the upper end surface of the box body 51, the sealing plug 521 can seal the opening of the reagent tube 55 to prevent the reagent from overflowing during the mixing process; since the spring 541 itself has elastic force, when reagent tubes 55 of different lengths squeeze the support plate 542, the support plate 542 has multiple moving positions. As the support plate 542 moves, the space of the accommodating chamber 512 changes, so that the accommodating chamber 512 can adapt to reagent tubes 55 of different lengths, thereby further improving the adaptability of the reagent mixing device 100.

[0041] In some embodiments, Figure 2 and Figure 3 As shown, the fixing structure 41 includes at least two buckles 411, both of which are installed on the mixing seat 4, and the two buckles 411 are arranged opposite to each other, and the number of the slots 511 corresponds to the buckles 411; the buckles 411 are in a barb-shaped structure, and the slots 511 are arranged on the side walls of the box body 51, and the buckles 411 cooperate with the slots 511. Specifically, when the reagent box 5 is installed on the mixing seat 4, the side walls of the reagent box 5 and the buckles 411 slide and cooperate, so that the buckles 411 slide into the slots 511 and are connected with the slots 511; between the two buckles 411 where the reagent box 5 is restricted, the buckle 411 is in a barb-shaped structure, which is used to hook the slots 511, thereby improving the stability of the reagent box 5 on the mixing seat 4 and preventing the reagent box 5 from falling during the flipping and mixing process.

[0042] In some embodiments, Figure 4As shown, the fixing structure 41 includes at least two limiting columns 412, the first end of the limiting column 412 is installed on the mixing seat 4, the card slot 511 is set on the box body 51, and the card slot 511 runs through from one end of the box body 51 to the other end of the box body 51; the card slot 511 is for the second end of the limiting column 412 to pass through, so that the second end of the limiting column 412 is against the upper end surface of the box body 51, and the lower end surface of the box body 51 is against the mixing seat 4. Specifically, the two limiting posts 412 realize a two-point connection between the mixing seat 4 and the reagent box 5, thereby preventing the reagent box 5 from moving on the mixing seat 4; and the limiting posts 412 are at least partially made of elastic material, so that the limiting posts 412 have a certain elasticity, and the top of the limiting posts 412 has a retractable space; when the reagent box 5 is assembled with the mixing seat 4, after the top of the limiting posts 412 passes through the card slot 511, the top of the limiting posts 412 abuts against the upper end surface of the box body 51, and the box body 51 is restricted on the mixing seat 4, and the two ends of the box body 51 respectively abut against the mixing seat 4 and the top of the limiting posts 412, thereby improving the stability of the reagent box 5 on the mixing seat 4.

[0043] Preferably, Figure 5 As shown, the limiting column 412 includes at least three elastic rods 4120, which are arranged in a matrix, with a gap 4123 between two adjacent elastic rods 4120, and the diameter of the first end of the elastic rod 4120 is greater than the diameter of the second end of the elastic rod 4120. Specifically, when the first ends of the three elastic rods 4120 move in the card slot 511, they are squeezed by the inner wall of the card slot 511. After the first ends of the three elastic rods 4120 pass through the card slot 511, the three elastic rods 4120 are unfolded, so that the first ends of the three elastic rods 4120 are all against the box body 51, and further the two ends of the box body 51 are respectively against the top of the mixing seat 4 and the limiting column 412. When the reagent box 5 needs to be removed, the three elastic rods 4120 are squeezed to make the three elastic rods 4120 approach each other, the gap 4123 is reduced, and the tops of the three elastic rods 4120 can be moved into the slot 511 to remove the reagent box 5 from the limiting column 412.

[0044] Preferably, Figure 5 As shown, the elastic rod 4120 includes a supporting portion 4121 and an abutting portion 4122, wherein the abutting portion 4122 is mounted on the supporting portion 4121, and the cross-sectional area of ​​the abutting portion 4122 is larger than the cross-sectional area of ​​the supporting portion 4121. Specifically, the abutting portion 4122 is used to abut against the upper end surface of the box body 51 to limit the movement of the reagent kit 5 on the mixing seat 4; the supporting portion 4121 is used to support the box body 51, increase the contact area between the box body 51 and the limiting column 412, and thus improve the stability of the reagent kit 5 on the mixing seat 4.

[0045] Preferably, Figure 5As shown, the elastic rod 4120 is in a barb-shaped structure. Specifically, the barbs of the three elastic rods 4120 hook the upper end surface of the box body 51, increasing the contact area between the limiting column 412 and the box body 51, and further preventing the box body 51 from moving on the mixing seat 4.

[0046] Preferably, Figure 1 and Figure 2 As shown, the reagent mixing device 100 also has an elastic band 42, both ends of which are connected to the mixing seat 4, and the reagent box 5 is arranged between the inner wall of the elastic band 42 and the outer side of the mixing seat 4. The elastic band 42 fixes the reagent box 5 on the mixing seat 4, and the elastic force applied by the elastic band 42 acts on the cover 52, so that the cover 52 squeezes the box body 51, so that the sealing plug 521 on the cover 52 seals the opening of the reagent tube 55; moreover, the elastic band 42 can further improve the stability of the reagent box 5 on the mixing seat 4.

[0047] In some embodiments, Figure 2 As shown, the driving assembly 3 includes a motor 33, a rotating shaft 34, and a bearing 36. The reagent mixing device 100 also has a housing 1 and a support 21. The housing 1 is mounted on the first end of the base 2, and the support 21 is mounted on the second end of the base 2. The housing 1 and the support 21 are arranged opposite to each other. The motor 33 is arranged in the housing 1, and the mixing seat 4 is sleeved on the outside of the rotating shaft 34. The first end of the rotating shaft 34 is mounted on the output end of the motor 33. The bearing 36 is sleeved on the outside of the second end of the rotating shaft 34, and the bearing 36 is arranged on the support 21. The second end of the rotating shaft 34 is rotatably matched with the support 21 through the bearing 36. Specifically, the motor 33 is used to drive the rotating shaft 34 to rotate, so that the rotating shaft 34 drives the mixing seat 4 to rotate, and drives the reagent box 5 to realize the centrifugal mixing operation. The bearing 36 is used to support the second end of the rotating shaft 34, and makes the rotating shaft 34 rotate on the support 21, reducing the friction resistance of the rotation of the rotating shaft 34. The support 21 is used to reduce the stress of the motor 33 to avoid damage to the motor 33 due to excessive stress.

[0048] In addition, if Figure 1 and Figure 2 As shown, the housing 1 also has a circuit board 35, and the outer surface of the housing 1 is provided with an adjusting knob 31 and a switch key 32. The circuit board 35 has a control circuit. The adjusting knob 31 and the switch key 32 are electrically connected to the circuit board 35. The adjusting knob 31 is used to control the rotation speed of the motor 33, and the switch key 32 is used to turn on or off the motor 33, so as to facilitate the control of the operation of the reagent mixing device 100.

[0049] In some embodiments, the reagent box 5 has a pin 53, the first end of the pin 53 is mounted on the box body 51, and the end of the cover 52 is sleeved outside the pin 53 and rotates with the pin 53. Specifically, the first end of the cover 52 is rotatably connected to the box body 51 through the pin 53, and the accommodating cavity 512 can be opened by acting on the second end of the cover 52; of course, the cover 52 and the box body 51 are also connected by a snap-fit ​​method, which is not particularly limited here.

[0050] It should be noted that the reagent mixing device 100 is used to centrifuge the reagent during the reagent mixing operation. Reagent tubes 55 of different capacities are sealed by the cover 52 through the elastic component 54, thereby improving the adaptability of the reagent mixing device 100. In other embodiments, the elastic force or telescopic range of the elastic component 54 can be flexibly set according to the size of the reagent tube 55, and no special restrictions are made here.

[0051] When quoting drawing descriptions, new features that appear are described; in order to avoid repeated quotations of drawings resulting in less concise descriptions, features that have been described clearly will not be quoted in the drawings one by one.

[0052] The purpose of the above embodiments is to exemplarily reproduce and deduce the technical solution of the utility model, and to fully describe the technical solution, purpose and effect of the utility model. Its purpose is to make the public understand the disclosed content of the utility model more thoroughly and comprehensively, and it does not limit the protection scope of the utility model.

[0053] The above embodiments are not exhaustive enumerations based on the present invention, and there may be multiple other implementations not listed. Any replacement and improvement made without violating the concept of the present invention shall fall within the protection scope of the present invention.

Claims

1. A reagent mixing device, characterized in that: include: A base, a driving component, a mixing seat, and a reagent box, wherein the driving component is installed on the base, and the mixing seat is installed at the output end of the driving component; The test kit includes a box body, a cover body, and an elastic component. The box body has at least one accommodating cavity. The cover body is installed on the box body and is used to seal the accommodating cavity. The elastic component is installed on the bottom wall of the accommodating cavity, and the expansion and contraction direction of the elastic component is consistent with the depth direction of the accommodating cavity.

2. The reagent mixing device according to claim 1, characterized in that: The elastic component includes a spring and a support plate, wherein the spring is arranged at the bottom of the accommodating cavity, and the support plate is installed on the spring; The cover body has a sealing plug corresponding to the accommodating cavity, and the sealing plug is arranged above the supporting plate; The support plate has at least two moving positions in the accommodating cavity. In the first moving position, the support plate is close to the bottom of the accommodating cavity, and the space of the accommodating cavity is increased; in the second moving position, the support plate is away from the bottom of the accommodating cavity, and the space of the accommodating cavity is reduced.

3. The reagent mixing device according to claim 1, characterized in that: The mixing seat is provided with a fixing structure, and the reagent box is provided with a slot matched with the fixing structure.

4. The reagent mixing device as claimed in claim 3, characterized in that: The fixing structure includes at least two buckles, both of which are mounted on the mixing seat and arranged opposite to each other, and the number of the slots corresponds to the number of the buckles; The buckle is in a barb-shaped structure, the slot is arranged on the side wall of the box body, and the buckle cooperates with the slot.

5. The reagent mixing device as claimed in claim 3, characterized in that: The fixing structure includes at least two limiting columns, the first ends of which are mounted on the mixing seat, and the slots are arranged on the box body, and the slots extend from one end of the box body to the other end of the box body; The second end of the limiting column is passed through the slot, so that the second end of the limiting column abuts against the upper end surface of the box body, and the lower end surface of the box body abuts against the mixing seat.

6. The reagent mixing device as claimed in claim 5, characterized in that: The limiting column comprises at least three elastic rods, which are arranged in a matrix, with a gap between two adjacent elastic rods, and the diameter of the first end of the elastic rod is greater than the diameter of the second end of the elastic rod.

7. The reagent mixing device according to claim 6, characterized in that: The elastic rod comprises a supporting portion and an abutting portion, wherein the abutting portion is mounted on the supporting portion, and a cross-sectional area of ​​the abutting portion is greater than a cross-sectional area of ​​the supporting portion.

8. The reagent mixing device according to claim 6, characterized in that: The elastic rod is in a barb-shaped structure.

9. The reagent mixing device according to any one of claims 1 to 8, characterized in that: The reagent mixing device also has an elastic band, both ends of which are connected to the mixing seat, and the reagent box is arranged between the inner wall of the elastic band and the outer side of the mixing seat.

10. The reagent mixing device according to any one of claims 1 to 8, characterized in that: The driving assembly includes a motor, a rotating shaft, and a bearing. The reagent mixing device also includes a housing and a support member. The housing is mounted on a first end of the base, and the support member is mounted on a second end of the base. The housing and the support member are arranged opposite to each other. The motor is arranged in the shell, the mixing seat is sleeved on the outside of the rotating shaft, the first end of the rotating shaft is installed on the output end of the motor, the bearing is sleeved on the outside of the second end of the rotating shaft, and the bearing is arranged on the support member, and the second end of the rotating shaft is rotatably matched with the support member through the bearing.

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