Liquid-based cell and microbiological treatment, preservation and staining kit

Abstract

The utility model relates to the technical field of liquid-based cell and microbiological treatment, preservation and staining, in particular to a liquid-based cell and microbiological treatment, preservation and staining kit, which comprises a blister box body and a cell preservation liquid groove arranged inside the blister box body. A Pasteur staining solution groove, a membrane cup groove, a gram staining solution groove, a sampler groove, a cell lysis solution groove, an extracting solution groove, a microorganism sample preservation solution groove, a sample diluent groove, a sample density separation solution groove, a sample releasing agent groove and an anti-falling slide groove are formed in the blister box body. The handle drives the screw rod to rotate, the screw rod drives the two wedge-shaped blocks to slide, the wedge-shaped blocks drive the rolling wheels to move, the rolling wheels drive the supporting rods to move upwards, the supporting rods drive the supporting plates to slide upwards, the supporting plates jack up various reagent bottles, the sampling devices and the anti-falling-off slides to enable the reagent bottles, the sampling devices and the anti-falling-off slides to be partially exposed out of the plastic uptake box body, taking is convenient, and when the plastic uptake box is used, the needed reagent bottles can be taken out conveniently.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid-based cell and microorganism processing, preservation and staining, and particularly relates to a liquid-based cell and microorganism processing, preservation and staining kit. Background Technique

[0002] For the detection of various types of samples, especially the formed components such as cells and microorganisms in body fluid samples, a certain pre-treatment process is required. This pre-treatment can improve the positive detection rate and reduce the final detection of impurities in the sample on the formed components.

[0003] For example, a liquid-based cell and microorganism processing, preservation and staining kit with the patent number CN208667742U includes a plastic suction box body, a cell preservation liquid bottle, a Papanicolaou staining liquid bottle, a membrane cup, a Gram staining liquid bottle, a sampler, a cell lysate bottle, an extraction liquid bottle, a microorganism sample preservation liquid bottle, a sample diluent bottle, a sample density separation liquid bottle, a sample release agent bottle, and an anti-shedding glass slide. The above document still has deficiencies. When in use, for the whole process of cell or microorganism sampling, preservation, transportation, lysis, extraction, separation, precipitation, fixation, slide preparation, and staining of various types of samples, it provides a full range of reagent supplies. This combined use greatly facilitates the operator, improves work efficiency, and standardizes the entire detection process. However, after the various reagent bottles used in the above document are placed in the corresponding grooves in the plastic suction box body, the sizes of the reagent bottles and the corresponding grooves just match. When in use, it is not convenient to take out the required reagent bottles. At the same time, the plastic suction box body in the above document has an open design, and a lot of dust is likely to fall on the surface of the reagent bottles during the placement process, and it is necessary to clean them one by one, and the operation is relatively troublesome. Content of the Utility Model

[0004] The purpose of the utility model is to solve the problem that it is not convenient to take out the required reagent bottles, and a liquid-based cell and microorganism processing, preservation and staining kit is proposed.

[0005] To achieve the above purpose, the utility model provides the following technical solution:

[0006] Design a liquid-based cell and microorganism processing, preservation and staining kit, including a plastic suction box body and a cell preservation liquid groove. The cell preservation liquid groove is arranged inside the plastic suction box body. Inside the plastic suction box body, there are a Papanicolaou staining liquid groove, a membrane cup groove, a Gram staining liquid groove, a sampler groove, a cell lysate groove, an extraction liquid groove, a microorganism sample preservation liquid groove, a sample diluent groove, a sample density separation liquid groove, a sample release agent groove, and an anti-shedding glass slide groove. A jacking mechanism is arranged inside the plastic suction box body, and a protection mechanism is arranged on the surface of the plastic suction box body.

[0007] Preferably, the jacking mechanism includes a screw rod. The outer walls at both ends of the screw rod are rotatably connected to the plastic suction box body through bearings. A handle is fixedly connected to the end of the screw rod. Two wedge-shaped blocks are threadedly connected to the outer wall of the screw rod. The outer walls of both wedge-shaped blocks are slidably connected to the plastic suction box body. The outer wall of the wedge-shaped block is in contact with a roller. The roller is rotatably connected to a support rod through a bearing. A support plate is fixedly connected to the upper end of the support rod.

[0008] Preferably, the protection mechanism includes a sleeve. The sleeve is fixedly connected to the surface of the plastic suction box body. A sliding rod is slidably connected inside the sleeve. A spring is arranged inside the sleeve. The two ends of the spring are fixedly connected to the sleeve and the sliding rod respectively. A locking rod is fixedly connected to the end of the sliding rod. The end of the locking rod is engaged with a card slot arranged inside a connecting plate. The connecting plate is fixedly connected to the surface of the cover plate. The cover plate is rotatably connected to the plastic suction box body through a hinge.

[0009] Preferably, the outer wall of the support plate is slidably connected to the plastic suction box body.

[0010] Preferably, a transparent window is arranged inside the cover plate.

[0011] For a liquid-based cell and microorganism processing, preservation and staining kit proposed by the present utility model, the beneficial effects are as follows: Through the cooperation among the screw rod, the handle, the wedge-shaped blocks, the rollers, the support rods and the support plate, the handle drives the screw rod to rotate. The screw rod drives the two wedge-shaped blocks to slide. The wedge-shaped blocks drive the rollers to move. The rollers drive the support rods to move upward. The support rods drive the support plate to slide upward. The support plate jacks up various reagent bottles, samplers and anti-detachment glass slides, so that a part of them leaks out of the plastic suction box body, facilitating taking. When in use, it is convenient to take out the required reagent bottles.

[0012] Through the cooperation among the sleeve, the sliding rod, the spring, the locking rod, the connecting plate and the cover plate, pull the two locking rods. The two locking rods move away from each other and drive the sliding rod to slide. The sliding rod slides inside the sleeve and stretches the spring. Flip the cover plate. The cover plate drives the connecting plate to move. The cover plate is buckled above the plastic suction box body. Release the locking rods. The spring drives the sliding rod to slide reversely under the action of elasticity, and then drives the locking rods to slide reversely. The end of the locking rod is inserted into the card slot arranged inside the connecting plate to fix the position of the connecting plate, thereby fixing the cover plate. The cover plate protects the inside of the plastic suction box body. Less dust will fall on the surface of the reagent bottles during the placement process, and it is not necessary to clean them one by one. The operation is relatively simple. Description of the Drawings

[0013] Figure 1 is a schematic structural diagram of the present utility model;

[0014] Figure 2 is a structural sectional view of the present utility model;

[0015] Figure 3This is a schematic structural diagram of the connection between the plastic suction box body, the membrane cup groove and the sampler groove in the present utility model;

[0016] Figure 4 This is a schematic structural diagram of the connection between the screw, the plastic suction box body and the cover plate in the present utility model;

[0017] Figure 5 This is a schematic structural diagram of the connection between the screw, the handle and the wedge block in the present utility model;

[0018] Figure 6 This is a schematic structural diagram of the connection between the sleeve, the spring and the slide bar in the present utility model.

[0019] In the figure: 1. Plastic suction box body, 2. Cell preservation liquid groove, 3. Lifting mechanism, 301. Screw, 302. Handle, 303. Wedge block, 304. Roller, 305. Support rod, 306. Support plate, 4. Protection mechanism, 401. Sleeve, 402. Slide bar, 403. Spring, 404. Locking rod, 405. Connecting plate, 406. Cover plate, 4a1. Support plate, 5. Papanicolaou staining liquid groove, 6. Membrane cup groove, 7. Gram staining liquid groove, 8. Sampler groove, 9. Cell lysate groove, 10. Extract groove, 11. Microbial sample preservation liquid groove, 12. Sample diluent groove, 13. Sample density separation liquid groove, 14. Sample release agent groove, 15. Anti-shedding glass slide groove, 16. Transparent window. Detailed implementation manners

[0020] The present utility model will be further described below with reference to the accompanying drawings:

[0021] Embodiment 1:

[0022] Refer to the attached Figure 1-6 : In this embodiment, a liquid-based cell and microorganism processing, preservation and staining kit includes a plastic suction box body 1 and a cell preservation liquid groove 2. The cell preservation liquid groove 2 is arranged inside the plastic suction box body 1. A cell preservation liquid reagent bottle is placed inside the cell preservation liquid groove 2. Inside the plastic suction box body 1, there are arranged a Papanicolaou staining liquid groove 5, a membrane cup groove 6, a Gram staining liquid groove 7, a sampler groove 8, a cell lysate groove 9, an extract groove 10, a microbial sample preservation liquid groove 11, a sample diluent groove 12, a sample density separation liquid groove 13, a sample release agent groove 14, and an anti-shedding glass slide groove 15;

[0023] The inner parts of the Papanicolaou staining solution groove 5, membrane cup groove 6, Gram staining solution groove 7, sampler groove 8, cell lysate groove 9, extraction solution groove 10, microbial sample preservation solution groove 11, sample diluent groove 12, sample density separation solution groove 13, sample release agent groove 14, and anti-shedding glass slide groove 15 are respectively placed with Papanicolaou staining solution reagent bottles, membrane cups, Gram staining solution reagent bottles, samplers, cell lysate reagent bottles, extraction solution reagent bottles, microbial sample preservation solution reagent bottles, sample diluent reagent bottles, sample density separation solution reagent bottles, sample release agent reagent bottles, and anti-shedding glass slides. A jacking mechanism 3 is arranged inside the plastic suction box body 1, and the jacking mechanism 3 facilitates the removal of the reagent bottles inside the plastic suction box body 1. A protection mechanism 4 is arranged on the surface of the plastic suction box body 1, and the protection mechanism 4 protects the reagent bottles inside the plastic suction box body 1.

[0024] The jacking mechanism 3 includes a screw 301, a handle 302, a wedge block 303, a roller 304, a support rod 305, and a tray 306. The outer walls at both ends of the screw 301 are rotatably connected to the plastic suction box body 1 through bearings. The end of the screw 301 is fixedly connected with the handle 302, and the handle 302 drives the screw 301 to rotate. The thread directions on both sides of the screw 301 are the same. Two wedge blocks 303 are threadedly connected to the outer wall of the screw 301, and the screw 301 drives the two wedge blocks 303 to slide.

[0025] The outer walls of the two wedge blocks 303 are slidably connected to the plastic suction box body 1. The outer wall of the wedge block 303 is in contact with the roller 304. The wedge block 303 drives the roller 304 to move. The roller 304 is rotatably connected to the support rod 305 through a bearing. The roller 304 drives the support rod 305 to move. The upper end of the support rod 305 is fixedly connected with the tray 306, and the support rod 305 drives the tray 306 to move. The outer wall of the tray 306 is slidably connected to the plastic suction box body 1.

[0026] The handle 302 drives the screw 301 to rotate. The screw 301 drives the two wedge blocks 303 to slide. The wedge block 303 drives the roller 304 to move. The roller 304 drives the support rod 305 to move upward. The support rod 305 drives the tray 306 to slide upward. The tray 306 jacks up various reagent bottles, samplers, and anti-shedding glass slides, making a part of them leak out of the plastic suction box body 1, facilitating taking. When in use, it is convenient to take out the required reagent bottles.

[0027] The protection mechanism 4 includes a sleeve 401, a sliding rod 402, a spring 403, a locking rod 404, a connecting plate 405, and a cover plate 406. The sleeve 401 is fixedly connected to the surface of the plastic suction box body 1. A sliding rod 402 is slidably connected inside the sleeve 401. There are two sliding rods 402, and the sliding rods 402 slide inside the sleeve 401. A spring 403 is arranged inside the sleeve 401, and the model of the spring 403 is selected according to actual use requirements as long as it meets the working needs.

[0028] Both ends of the spring 403 are fixedly connected to the sleeve 401 and the slide bar 402 respectively. Under the elastic action, the spring 403 can drive the slide bar 402 to slide. A locking bar 404 is fixedly connected to the end of the slide bar 402. The slide bar 402 drives the locking bar 404 to move. The end of the locking bar 404 is engaged with a card slot provided in the connecting plate 405. The locking bar 404 cooperates with the card slot provided in the connecting plate 405 to fix the position of the connecting plate 405. The connecting plate 405 is fixedly connected to the surface of the cover plate 406. The connecting plate 405 and the cover plate 406 move together. The cover plate 406 is rotatably connected to the plastic suction box body 1 through a hinge. A transparent window 16 is provided inside the cover plate 406. The transparent window 16 facilitates the observation of the inside of the plastic suction box body 1;

[0029] Pull the two locking bars 404. The two locking bars 404 move away from each other and drive the slide bar 402 to slide. The slide bar 402 slides inside the sleeve 403 and stretches the spring 403. Flip the cover plate 406. The cover plate 406 drives the connecting plate 405 to move. The cover plate 406 is buckled above the plastic suction box body 1. Release the locking bar 404. The spring 403 drives the slide bar 402 to slide in the reverse direction under the elastic action, and then drives the locking bar 404 to slide in the reverse direction. The end of the locking bar 404 is inserted into the card slot provided in the connecting plate 405 to fix the position of the connecting plate 405, and then fix the cover plate 406. The cover plate 406 protects the inside of the plastic suction box body 1. During the placement of the reagent bottle, less dust will fall on the surface, and it is not necessary to clean each one separately, and the operation is relatively simple.

[0030] Working principle:

[0031] All kinds of reagent bottles, samplers and anti-falling glass slides can be stored in the grooves inside the plastic suction box body 1. The storage positions are neat, which is convenient for personnel to take and use. The sampler can be used for sampling of microorganisms and liquid-based cells. Personnel use the test liquids inside the cell preservation liquid bottle, membrane cup, cell lysate reagent bottle, extraction liquid reagent bottle, microbial sample preservation liquid reagent bottle, sample diluent reagent bottle, sample density separation liquid reagent bottle, sample release agent reagent bottle and anti-falling glass slides and other items to perform operations such as preservation, transportation, extraction, separation, precipitation, fixation, and section preparation of liquid-based cells or microorganisms. The Papanicolaou staining solution inside the Papanicolaou staining solution reagent bottle can be used to stain liquid-based cells, and the Gram staining solution inside the Gram staining solution reagent bottle can be used to stain microorganisms to complete the treatment of liquid-based cells and microorganisms;

[0032] Reagent bottle taking stage:

[0033] When various reagent bottles, samplers, and anti-detachment glass slides are placed inside the plastic suction box body 1, their lower ends are all located on the support plate 306. When it is necessary to take out various reagent bottles, samplers, and anti-detachment glass slides, turn the handle 302. The handle 302 drives the screw rod 301 to rotate. The screw rod 301 drives two wedge-shaped blocks 303 to slide. The wedge-shaped blocks 303 drive the rollers 304 to move. The rollers 304 drive the support rod 305 to move upward. The support rod 305 drives the support plate 306 to slide upward. The support plate 306 jacks up various reagent bottles, samplers, and anti-detachment glass slides, making a part of them leak out of the plastic suction box body 1, facilitating taking. During use, it is convenient to take out the required reagent bottles;

[0034] Internal protection stage of the plastic suction box body:

[0035] After various reagent bottles, samplers, and anti-detachment glass slides are placed in the corresponding grooves inside the plastic suction box body 1, rotate the runner 302 in the reverse direction so that the upper ends of various reagent bottles, samplers, and anti-detachment glass slides are all lower than the upper edge position of the plastic suction box body 1. Pull two locking rods 404. The two locking rods 404 move away from each other and drive the sliding rod 402 to slide. The sliding rod 402 slides inside the sleeve 403 and stretches the spring 403. Flip the cover plate 406. The cover plate 406 drives the connecting plate 405 to move. The cover plate 406 is buckled on the top of the plastic suction box body 1. Release the locking rods 404. The spring 403 drives the sliding rod 402 to slide in the reverse direction under the elastic action, and then drives the locking rods 404 to slide in the reverse direction. The end of the locking rod 404 is inserted into the card slot provided in the connecting plate 405 to fix the position of the connecting plate 405, and then fix the cover plate 406. The cover plate 406 protects the inside of the plastic suction box body 1. Less dust will fall on the surface of the reagent bottle during the placement process, and it is not necessary to clean each of them one by one. The operation is relatively simple. When opening the cover plate 406, just pull the locking rod 404 to separate the end of the locking rod 404 from the card slot provided in the connecting plate 405, and then the cover plate 406 can be rotated to open it.

[0036] Embodiment 2:

[0037] Refer to the appendix Figure 1-6 In this embodiment, a liquid-based cytology and microorganism processing, preservation, and staining kit, the protection mechanism 4 further includes a support plate 4a1. The support plate 4a1 is fixedly connected to the surface of the locking rod 404, and the support plate 4a1 drives the locking rod 404 to move;

[0038] When it is necessary to pull the locking rod 404, toggle the support plate 4a1. The support plate 4a1 drives the locking rod 404 to move. It is convenient to pull the locking rod 404 through the support plate 4a1.

[0039] Working principle:

[0040] When it is necessary to pull the lock lever 404, the support plate 4a1 is toggled, and the support plate 4a1 drives the lock lever 404 to move, facilitating the pulling of the lock lever 404 through the support plate 4a1.

[0041] Although the present utility model has been illustrated and described by referring to the preferred embodiments, those of ordinary skill in the art should understand that various changes in form and details may be made within the scope of the claims.

Claims

1. A liquid-based cell and microorganism processing, preservation and staining kit, comprising a blister box body (1) and a cell preservation liquid groove (2), wherein the cell preservation liquid groove (2) is arranged inside the blister box body (1), characterized in that: The interior of the blister box body (1) is provided with a Papanicolaou staining solution groove (5), a membrane cup groove (6), a Gram staining solution groove (7), a sampler groove (8), a cell lysis solution groove (9), an extracting solution groove (10), a microorganism sample preservation solution groove (11), a sample diluent groove (12), a sample density separation solution groove (13), a sample release agent groove (14), and an anti-dropping glass slide groove (15); the interior of the blister box body (1) is provided with a lifting mechanism (3); and the surface of the blister box body (1) is provided with a protective mechanism (4).

2. A liquid-based cell and microorganism processing, preservation and staining kit according to claim 1, characterized in that: The lifting mechanism (3) comprises a screw rod (301), the outer walls at both ends of the screw rod (301) are rotatably connected to the blister box body (1) via bearings, a handle (302) is fixedly connected to the end of the screw rod (301), two wedge blocks (303) are threadedly connected to the outer wall of the screw rod (301), the outer walls of the two wedge blocks (303) are slidably connected to the blister box body (1), the outer walls of the wedge blocks (303) are fitted with a roller (304), the roller (304) is rotatably connected to a support rod (305) via a bearing, and a support plate (306) is fixedly connected to the upper end of the support rod (305).

3. A liquid-based cell and microorganism processing, preservation and staining kit according to claim 1, characterized in that: The protective mechanism (4) comprises a sleeve (401), wherein the sleeve (401) is fixedly connected to the surface of the blister box body (1), wherein the sleeve (401) is slidably connected to a slide rod (402) inside, wherein a spring (403) is arranged inside the sleeve (401), wherein two ends of the spring (403) are respectively fixedly connected to the sleeve (401) and the slide rod (402), wherein the end of the slide rod (402) is fixedly connected to a locking rod (404), wherein the end of the locking rod (404) is clamped to a clamping groove arranged in a connecting plate (405), wherein the connecting plate (405) is fixedly connected to the surface of a cover plate (406), and wherein the cover plate (406) is rotatably connected to the blister box body (1) through a hinge.

4. A liquid-based cell and microorganism processing, preservation and staining kit according to claim 2, characterized in that: The outer wall of the support plate (306) is slidably connected to the blister box body (1).

5. A liquid-based cell and microorganism processing, preservation and staining kit according to claim 3, characterized in that: A transparent window (16) is provided inside the cover plate (406).

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