Continuous flow drug synthesis reactor regulation and control system
By using a combination of a conical flow channel and a jet nozzle in a continuous flow drug synthesis reactor, efficient mixing and cleaning difficulty of the drug solution is reduced, the limitations of traditional stirring methods are solved, and the ability to flexibly switch agents is provided.
Patent Information
- Application Number
- CN202422002201.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-19
- Publication Date
- 2025-05-30
- Estimated Expiration
- 2034-08-19
AI Technical Summary
The existing continuous flow drug synthesis reactors rely on traditional mechanical stirring during the mixing process, which makes subsequent cleaning difficult and does not have the ability to flexibly select and switch different agents.
By setting the flow channel of the conical table in the reactor and the ejection nozzle, the pressure of the liquid supply is adjusted, so that the main base liquid and the reaction liquid are initially hedged and mixed with the liquid by using the properties of the liquid itself, and then the secondary flow of the drug in the flow hole on the barrier plate is mixed to increase the contact area of the reactants.
It realizes efficient mixing between liquids, reduces dependence on traditional stirring methods, reduces the difficulty of cleaning inside the reactor, and has the ability to flexibly switch different agents.
Smart Images

Figure CN222918662U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of pharmaceutical manufacturing, and particularly relates to a regulation system for a continuous flow drug synthesis reactor. Background Art
[0002] A drug synthesis reactor is an important device used in the process of chemical drug synthesis, which can realize the synthesis of drug molecules on a laboratory or industrial scale. The design and operation of a drug synthesis reactor are crucial for improving synthesis efficiency, controlling product quality, and ensuring the safety of the production process.
[0003] Currently, most continuous flow drug synthesis reactors still use traditional mechanical stirring methods for mixing, making it difficult to utilize the properties of the liquid itself for mixing, resulting in greater difficulty in the subsequent cleaning work of the stirring device and increasing the maintenance cost; in addition, existing continuous flow reactors usually do not have the ability to flexibly select and switch different reagents for mixing.
[0004] Therefore, it is necessary to provide a regulation system for a continuous flow drug synthesis reactor to solve the problems in the above background art. Summary of the Utility Model
[0005] In view of the above problems, the present application provides a regulation system for a continuous flow drug synthesis reactor. Through the cooperation of the flow channel of the conical platform and the injection nozzle, the pressure of the liquid supply is adjusted, so that the main base liquid and the reaction liquid are initially counter-jet mixed using the properties of the liquid itself, and then through the secondary flow mixing of the drug in the diversion holes on the baffle plate, the contact area between the reactants is increased, thereby accelerating the chemical reaction, facilitating the realization of efficient mixing between liquids, reducing the dependence on traditional stirring methods, and reducing the subsequent cleaning difficulty inside the reactor.
[0006] To achieve the purpose of the present application, the following technical solutions are provided in the present application:
[0007] The present application provides a continuous flow drug synthesis reactor regulation system, including: a reactor, a main liquid supply regulation unit, and a secondary liquid supply regulation unit. Among them, a main liquid inlet is fixedly arranged at the upper end of the reactor, and the main liquid supply regulation unit is arranged at the upper end of the reactor. The secondary liquid supply regulation unit is arranged at the lower end inside the reactor. The main liquid supply regulation unit includes a servo motor fixed to the upper end of the reactor. The output end of the servo motor is fixedly provided with a rotating rod. A conical platform is fixedly arranged at the lower end of the rotating rod. An expansion adjustment cylinder is fixedly arranged inside the rotating rod. The output end of the expansion adjustment cylinder is fixed with a flow isolation component. Four inclined flow channels are evenly arranged inside the conical platform. The flow channels are communicated with the main liquid inlet. The secondary liquid supply regulation unit includes a guide seat fixedly arranged at the bottom end inside the reactor. Four evenly distributed spray nozzles are fixedly arranged on the guide seat. The number and position of the flow channels and the spray nozzles are correspondingly arranged, and each spray nozzle is communicated with its corresponding secondary liquid supply mechanism.
[0008] In a possible implementation manner, a heating unit and a liquid outlet are further arranged on the reactor, and a support is fixedly arranged at the lower end of the reactor.
[0009] In a possible implementation manner, a main control unit is installed on the reactor. The main control unit is electrically connected to the main liquid supply regulation unit and the secondary liquid supply regulation unit respectively. A pressure regulation unit is arranged in both the main liquid supply regulation unit and the secondary liquid supply regulation unit. The pressure regulation unit and the heating unit are electrically connected to the main control unit.
[0010] In a possible implementation manner, a hollow chamber and an annular chamber are arranged inside the rotating rod. The expansion adjustment cylinder is fixedly arranged inside the hollow chamber. The output end of the expansion adjustment cylinder is fixed with a sliding rod. The flow isolation component is fixedly arranged at the lowermost end of the sliding rod. One end of the annular chamber is communicated with the main liquid inlet, and the other end of the annular chamber is communicated with the flow channels.
[0011] In a possible implementation manner, the flow isolation component includes a soft cushion layer and a base layer. The soft cushion layer and the base layer have the same structure, and both include a rotating partition plate fixed to the sliding rod. An installation hole is opened at the center of the rotating partition plate. The rotating partition plate is fixed to the sliding rod through the installation hole. Through holes one, two, three, and four are evenly arranged on the circumference of the rotating partition plate. Through holes five, six, and seven are evenly arranged on the rotating partition plate between through holes one and two. Through holes six and seven are opened on the rotating partition plate between through holes two and three. Through hole seven is opened on the rotating partition plate between through holes three and four.
[0012] In a possible implementation, the first through hole, the second through hole, the third through hole, and the fourth through hole are all correspondingly arranged opposite to the outlet of the flow channel.
[0013] In a possible implementation, the heating unit includes a heating channel fixed inside the reactor, and a plurality of flow blocking members are installed on the heating channel.
[0014] In a possible implementation, the flow blocking member includes a baffle plate fixed to the heating channel respectively. A central hole is formed at the center of the baffle plate, and a plurality of longitudinally distributed diversion holes are formed in half of the area of the baffle plate. The central hole is fixed to the guide seat.
[0015] The beneficial effects of the present utility model are as follows:
[0016] 1. Through the cooperation of the conical flow channel and the injection nozzle of the present utility model, the pressure of the liquid supply is adjusted, so that the main base liquid and the reaction liquid are initially counter-jet mixed by using the properties of the liquid itself. Then, through the secondary flow mixing of the drug in the diversion holes on the baffle plate, the contact area between the reactants is increased, thereby accelerating the chemical reaction, facilitating the efficient mixing between liquids, reducing the dependence on the traditional stirring method, and reducing the subsequent cleaning difficulty inside the reactor.
[0017] 2. Through the cooperation of the flow channel and the flow isolation component of the present utility model, the start and stop of the liquid supply of the main base liquid into the reactor can be adjusted and switched, and the injection nozzle at the corresponding position can be selectively used, so that the main base liquid can be flexibly switched to be mixed with different medicaments, and multiple secondary liquid supply mechanisms can also be operated in parallel, facilitating multi-step synthesis reactions. Description of the Drawings
[0018] The drawings are used to provide a further understanding of the present application, and constitute a part of the specification. They are used together with the embodiments of the present application to explain the present application, and do not constitute a limitation to the present application;
[0019] Figure 1 It is a schematic diagram of the overall module structure of the present utility model;
[0020] Figure 2 It is a schematic diagram of the overall internal sectional structure of the present utility model;
[0021] Figure 3 It is a schematic diagram of the structure of the main liquid supply adjustment unit in the present utility model;
[0022] Figure 4 It is a schematic diagram of the structure of the flow isolation component in the present utility model;
[0023] Figure 5 It is a schematic diagram of the structure of the flow blocking member in the present utility model;
[0024] Reference numerals: 1, reactor; 2, main liquid inlet; 3, heating unit; 4, main liquid supply regulating unit; 5, secondary liquid supply regulating unit; 6, flow blocking member; 7, support; 8, liquid outlet; 31, heating channel; 41, servo motor; 42, rotating rod; 43, telescopic adjusting cylinder; 44, conical platform; 45, flow separating assembly; 51, guide seat; 52, injection nozzle; 421, hollow chamber; 422, annular chamber; 431, sliding rod; 441, flow channel; 451, rotating partition; 452, mounting hole; 453, through hole one; 454, through hole two; 455, through hole three; 456, through hole four; 457, through hole five; 458, through hole six; 459, through hole seven; 61, flow blocking partition; 62, central hole; 63, diversion hole. Detailed implementation manners
[0025] To make the objectives, technical solutions and advantages of the present application clearer, the technical solutions in the present application will be clearly and completely described below with reference to the accompanying drawings in the present application. Obviously, the described embodiments are some, but not all, of the embodiments of the present application. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present application without creative efforts shall fall within the protection scope of the present application.
[0026] The terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of such features; in the description of the present application, unless otherwise specified, the meaning of "a plurality" is three or more.
[0027] Figures 1-5A continuous flow drug synthesis reactor control system provided by an embodiment of the present application includes: a reactor 1, a main liquid supply adjustment unit 4, and a secondary liquid supply adjustment unit 5. Among them, a main liquid inlet 2 is fixedly arranged at the upper end of the reactor 1, and the main liquid supply adjustment unit 4 is arranged at the upper end of the reactor 1. The secondary liquid supply adjustment unit 5 is arranged at the lower end inside the reactor 1. The main liquid supply adjustment unit 4 includes a servo motor 41 fixed to the upper end of the reactor 1. The output end of the servo motor 41 is fixedly provided with a rotating rod 42. A conical platform 44 is fixedly arranged at the lower end of the rotating rod 42. An expansion adjustment cylinder 43 is fixedly arranged inside the rotating rod 42. The output end of the expansion adjustment cylinder 43 is fixed with a flow isolation component 45. Four inclined flow channels 441 are uniformly arranged inside the conical platform 44. The flow channels 441 are communicated with the main liquid inlet 2. The secondary liquid supply adjustment unit 5 includes a guide seat 51 fixedly arranged at the bottom end inside the reactor 1. Four uniformly distributed injection nozzles 52 are fixedly arranged on the guide seat 51. The number and positions of the flow channels 441 and the injection nozzles 52 correspond to each other. And each injection nozzle 52 is communicated with its corresponding secondary liquid supply mechanism.
[0028] Based on the above technical solution, first, the main base liquid is supplied into the flow channels 441 through the main liquid inlet 2. The operator selectively starts the gear of the servo motor 41 according to the requirements, which is divided into the following four situations:
[0029] When only one flow channel 441 is opened, the injection nozzle 52 corresponding to the opened flow channel 441 is communicated with the secondary liquid supply mechanism. At this time, the main base liquid at one outlet is preliminarily mixed with a reaction liquid in a counter-jet manner.
[0030] When only two flow channels 441 are opened, the injection nozzles 52 corresponding to the opened flow channels 441 are communicated with the secondary liquid supply mechanism. At this time, the main base liquid at two outlets is preliminarily mixed with two reaction liquids in a counter-jet manner.
[0031] When only three flow channels 441 are connected, the injection nozzles 52 corresponding to the opened flow channels 441 are communicated with the secondary liquid supply mechanism. At this time, the main base liquid at three outlets is preliminarily mixed with three reaction liquids in a counter-jet manner.
[0032] When all four flow channels 441 are opened, all the injection nozzles 52 are communicated with the secondary liquid supply mechanism. At this time, the main base liquid at four outlets is preliminarily mixed with four reaction liquids in a counter-jet manner.
[0033] On the basis of the above technical solution, through the cooperation of the flow channels 441 of the conical platform 44 and the injection nozzles 52, the main base liquid and the reaction liquid are preliminarily mixed in a counter-jet manner by using the properties of the liquid itself, which is beneficial to achieving efficient mixing between liquids, reducing the dependence on the traditional stirring method, and reducing the subsequent cleaning difficulty inside the reactor 1.
[0034] In a possible implementation manner, a heating unit 3 and a liquid outlet 8 are further installed on the reactor 1, and a support 7 is fixedly arranged at the lower end of the reactor 1, and the mixed liquid medicine is pumped out from the liquid outlet 8.
[0035] In a possible implementation manner, a main control unit is installed on the reactor 1. The main control unit is electrically connected to the main liquid supply adjustment unit 4 and the secondary liquid supply adjustment unit 5 respectively. Pressure adjustment units are arranged in both the main liquid supply adjustment unit 4 and the secondary liquid supply adjustment unit 5, and both the pressure adjustment unit and the heating unit 3 are electrically connected to the main control unit.
[0036] By adopting the above technical solution, the corresponding number of reaction liquids are selected according to actual needs and fed into the corresponding secondary liquid supply mechanisms. Then, the rotation of the servo motor 41 is controlled by the main control unit to adjust the opening of the corresponding number of flow channels 441 on the conical platform 44. The main control unit then controls the pressure adjustment unit to adjust the supply pressures of the main base liquid and the reaction liquid and the temperature of the heating unit 3 matching the reaction, so that the main base liquid and the reaction liquid react in the reactor 1.
[0037] In a possible implementation manner, a hollow chamber 421 and an annular chamber 422 are formed in the rotating rod 42. The telescopic adjustment cylinder 43 is fixedly arranged in the hollow chamber 421, and an output end of the telescopic adjustment cylinder 43 is fixed with a sliding rod 431. A flow isolation component 45 is fixedly arranged at the lowermost end of the sliding rod 431. One end of the annular chamber 422 is communicated with the main liquid inlet 2, and the other end of the annular chamber 422 is communicated with the flow channels 441.
[0038] By the above technical solution, when the flow isolation component 45 needs to rotate, the telescopic adjustment cylinder 43 controls the sliding rod 431 to extend, and the flow isolation component 45 moves away from the conical platform 44. Then, the servo motor 41 is started, and the flow isolation component 45 rotates. Then, the telescopic adjustment cylinder 43 contracts again, and the flow isolation component 45 fits with the conical platform 44, completing the opening and closing adjustment work of the flow channels 441 on the conical platform 44.
[0039] In a possible implementation manner, the flow isolation component 45 includes a soft cushion layer and a base layer. The soft cushion layer and the base layer have the same structure, and both include a rotating partition plate 451 fixed to the sliding rod 431. An installation hole 452 is provided at the center of the axis of the rotating partition plate 451. The rotating partition plate 451 is fixed to the sliding rod 431 through the installation hole 452. And through holes one 453, through holes two 454, through holes three 455, and through holes four 456 are evenly provided in the circumferential direction of the rotating partition plate 451. Through holes five 457, through holes six 458, and through holes seven 459 are evenly provided on the rotating partition plate 451 between the through holes one 453 and the through holes two 454. Through holes six 458 and through holes seven 459 are provided on the rotating partition plate 451 between the through holes two 454 and the through holes three 455. Through holes seven 459 are provided on the rotating partition plate 451 between the through holes three 455 and the through holes four 456. After the flow isolation component 45 rotates, under the contraction action of the telescopic adjusting cylinder 43, the soft cushion layer rises, and the rotating partition plate 451 can be attached to the lower surface of the conical platform 44, so as to block or open the flow channel 441.
[0040] In a possible implementation manner, the through holes one 453, the through holes two 454, the through holes three 455, and the through holes four 456 are all correspondingly arranged opposite to the outlet of the flow channel 441.
[0041] It should be noted that in the initial stage, the through holes one 453, the through holes two 454, the through holes three 455, and the through holes four 456 are all connected to the flow channel 441. Subsequently, the flow isolation component 45 can be selectively rotated according to actual needs, so as to adjust the opening or closing of each flow channel 441.
[0042] That is, in the initial stage, the through holes one 453, the through holes two 454, the through holes three 455, and the through holes four 456 are all connected to the flow channel 441. At this time, the main base liquid at the four outlets is initially mixed with the four reaction liquids in a counterflush manner; after the flow isolation component 45 rotates by 22.5°, the through holes five 457 are connected to the flow channel 441. At this time, the main base liquid at one outlet is initially mixed with one reaction liquid in a counterflush manner; after the flow isolation component 45 rotates by 45°, the through holes six 458 are connected to the flow channel 441. At this time, the main base liquid at two outlets is initially mixed with two reaction liquids in a counterflush manner; after the flow isolation component 45 rotates by 67.5°, the through holes seven 459 are connected to the flow channel 441. At this time, the main base liquid at three outlets is initially mixed with three reaction liquids in a counterflush manner, so that the reaction liquids at each outlet of the nozzle 52 can be initially mixed with the main base liquid at the outlet of each flow channel 441 in a counterflush manner.
[0043] In a possible implementation manner, the heating unit 3 includes a heating channel 31 fixedly arranged inside the reactor 1, and a plurality of flow blocking members 6 are installed on the heating channel 31. The flow blocking members 6 enable the liquid medicine after preliminary counter-jet mixing to perform secondary flow mixing.
[0044] It should be noted that the liquid medicine of preliminary counter-jet mixing is the mixture of the main base liquid and each reaction liquid, while the secondary flow mixing is for the flow mixing between the reaction liquids.
[0045] In a possible implementation manner, the flow blocking member 6 includes a flow blocking plate 61 fixedly arranged with the heating channel 31 respectively. A central hole 62 is opened at the center of the flow blocking plate 61, and a plurality of longitudinally distributed diversion holes 63 are opened in half of the area of the flow blocking plate 61. The central hole 62 is fixedly arranged with the guide seat 51.
[0046] Adopting the above technical solution, the flow blocking plate 61 with the diversion holes 63 opened is the opening area, and the flow blocking plate 61 without the diversion holes 63 opened is the non-opening area. The opening areas of the upper flow blocking plates 61 are correspondingly arranged with the non-opening areas of the lower flow blocking plates 61. The liquid medicine after preliminary counter-jet mixing falls at the uppermost flow blocking plate 61. At this time, the liquid medicine is on the flow blocking plate 61 and can fall into the non-opening area of the next flow blocking plate 61 from top to bottom along the diversion holes 63. Then the liquid medicine enters the diversion holes 63 in the opening area along the non-opening area of the flow blocking plate 61 and falls to the bottom of the reactor 1, enabling the liquid medicine to perform secondary flow mixing. Finally, the liquid medicine that has completed two mixings is pumped out from the liquid outlet 8.
[0047] Based on the above technical solution, the secondary flow mixing of the medicine in the diversion holes 63 of the flow blocking plate 61 increases the contact area between the reactants, thereby accelerating the chemical reaction between the reactants. Through the cooperation of the flow channel 441 and the flow isolation assembly 45, the start and stop of the supply of the main base liquid into the reactor 1 can be adjusted and switched, and the corresponding spray nozzles 52 at the corresponding positions can be selectively used, so that the main base liquid can be flexibly switched to be mixed with different medicaments, and multiple secondary liquid supply mechanisms can also be operated in parallel, facilitating multi-step synthesis reactions.
[0048] Working principle:
[0049] The operator first determines the start, stop and adjustment operations of the heating unit 3, and then supplies the main base liquid into the flow channel 441 through the main liquid inlet 2. The operator selectively starts the gears of the servo motor 41 according to the requirements, which are divided into the following four situations:
[0050] When the through hole five 457 is connected to the corresponding flow channel 441 and the other flow channels 441 are all closed, the spray nozzle 52 corresponding to the opened flow channel 441 is connected to the secondary liquid supply mechanism, and the pressure adjustment unit is started. The main base liquid at one outlet is preliminarily mixed with a reaction liquid in a counter-jet manner;
[0051] When the through hole six 458 communicates with the corresponding flow channel 441 and the other flow channels 441 are all closed, the injection nozzle 52 corresponding to the opened flow channel 441 communicates with the secondary liquid supply mechanism, and the pressure regulating unit is started, and the main base liquid at the two outlets and the two reaction liquids are subjected to a preliminary mixing in a counter-jet manner;
[0052] When the through hole seven 459 communicates with the corresponding flow channel 441 and the other flow channels 441 are closed, the injection nozzle 52 corresponding to the opened flow channel 441 communicates with the secondary liquid supply mechanism, and the pressure regulating unit is started, and the main base liquid at the three outlets and the three reaction liquids are subjected to a preliminary mixing in a counter-jet manner;
[0053] When the through hole one 453, the through hole two 454, the through hole three 455, and the through hole four 456 all communicate with the flow channel 441, the injection nozzles 52 all communicate with the secondary liquid supply mechanism, and the pressure regulating unit is started, and the main base liquid at the four outlets and the four reaction liquids are subjected to a preliminary mixing in a counter-jet manner;
[0054] The liquid medicine after the preliminary mixing falls to the baffle plate 61. At this time, the liquid medicine flows downward along the diversion holes 63 for secondary flow mixing, and the liquid medicine after the two-time mixing is pumped out from the liquid outlet 8.
[0055] The above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit it. The present application is not limited to the exact structures already described and illustrated in the drawings, and it cannot be considered that the specific implementation of the present application is only limited to these descriptions. For those of ordinary skill in the technical field to which the present application belongs, without departing from the concept of the present application, various changes and deformations made should be regarded as belonging to the protection scope of the present application.
Claims
1. A continuous flow drug synthesis reactor control system, characterized in that: include: A reactor (1), a main liquid supply regulating unit (4), and a secondary liquid supply regulating unit (5), wherein a main liquid inlet (2) is fixedly provided at the upper end of the reactor (1), and the main liquid supply regulating unit (4) is installed at the upper end of the reactor (1), and the secondary liquid supply regulating unit (5) is installed at the lower end of the reactor (1), and the main liquid supply regulating unit (4) comprises a servo motor (41) fixedly provided at the upper end of the reactor (1), a rotating rod (42) is fixedly provided at the output end of the servo motor (41), a conical platform (44) is fixedly provided at the lower end of the rotating rod (42), and a telescopic The adjusting cylinder (43) is provided with a flow partition component (45) fixed at the output end of the telescopic adjusting cylinder (43); four inclined flow channels (441) are evenly arranged in the conical platform (44); the flow channels (441) are connected to the main liquid inlet (2); the secondary liquid supply adjusting unit (5) comprises a guide seat (51) fixedly arranged at the bottom end of the reactor (1); four evenly distributed injection nozzles (52) are fixedly arranged on the guide seat (51); the number and position of the flow channels (441) and the injection nozzles (52) are correspondingly arranged, and each of the injection nozzles (52) is connected to its corresponding secondary liquid supply mechanism.
2. A continuous flow drug synthesis reactor control system according to claim 1, characterized in that: The reactor (1) is also provided with a heating unit (3) and a liquid outlet (8), and a bracket (7) is fixedly provided at the lower end of the reactor (1).
3. A continuous flow drug synthesis reactor control system according to claim 2, characterized in that: The reactor (1) is provided with a main control unit, the main control unit being electrically connected to the main liquid supply regulating unit (4) and the secondary liquid supply regulating unit (5), respectively, and the main liquid supply regulating unit (4) and the secondary liquid supply regulating unit (5) are both provided with pressure regulating units, and the pressure regulating unit and the heating unit (3) are both electrically connected to the main control unit.
4. A continuous flow drug synthesis reactor control system according to claim 1, characterized in that: The rotating rod (42) is provided with a hollow chamber (421) and an annular chamber (422); the telescopic adjustment cylinder (43) is fixedly arranged in the hollow chamber (421); a sliding rod (431) is fixedly arranged at the output end of the telescopic adjustment cylinder (43); the flow isolation component (45) is fixedly arranged at the lower end of the sliding rod (431); one end of the annular chamber (422) is connected to the main liquid inlet (2); and the other end of the annular chamber (422) is connected to the flow channel (441).
5. A continuous flow drug synthesis reactor control system according to claim 4, characterized in that: The flow isolation component (45) includes a cushion layer and a base layer. The cushion layer and the base layer have the same structure and both include a rotating baffle (451) fixed to the sliding rod (431). A mounting hole (452) is provided at the axis of the rotating baffle (451). The rotating baffle (451) is fixed to the sliding rod (431) through the mounting hole (452). The rotating baffle (451) is evenly provided with a first through hole (453), a second through hole (454), a third through hole (455), and a fourth through hole (456) on the circumference of the rotating baffle (451). 6), through hole five (457), through hole six (458), and through hole seven (459) are evenly arranged on the transfer baffle plate (451) between the through hole one (453) and the through hole two (454), through hole six (458) and through hole seven (459) are arranged on the transfer baffle plate (451) between the through hole two (454) and the through hole three (455), and through hole seven (459) is arranged on the transfer baffle plate (451) between the through hole three (455) and the through hole four (456).
6. A continuous flow drug synthesis reactor control system according to claim 5, characterized in that: The through hole one (453), the through hole two (454), the through hole three (455) and the through hole four (456) are all arranged corresponding to the outlet of the flow channel (441).
7. A continuous flow drug synthesis reactor control system according to claim 2, characterized in that: The heating unit (3) comprises a heating channel (31) fixed to the interior of the reactor (1), and a plurality of flow-blocking components (6) are installed on the heating channel (31).
8. A continuous flow drug synthesis reactor control system according to claim 7, characterized in that: The baffle (6) comprises baffle plates (61) respectively fixed to the heating channels (31); a center hole (62) is provided at the center of the baffle plate (61); and a plurality of longitudinally distributed flow guide holes (63) are provided in a half area of the baffle plate (61); the center hole (62) is fixed to the guide seat (51).