Online lossless reagent replacing device

Abstract

The utility model relates to the technical field of medical IVD equipment liquid paths, in particular to an online lossless reagent replacing device which comprises a control unit, a liquid path unit and an adjusting unit. The control unit comprises a metering pump, a first three-way valve and a second three-way valve, one end of the first three-way valve is connected with the metering pump, one port of the second three-way valve is fixedly connected with the metering pump, and the other two ports of the second three-way valve are connected with external positive and negative air pressure respectively; the online reagent adding device meets the requirement of online lossless reagent replacement of medical IVD equipment, and is simple in structure, high in reagent adding progress, lossless and low in cost.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid circuits of medical IVD devices, and particularly relates to an online reagent replacement device without loss. Background Art

[0002] The operation of various medical IVD devices usually requires adding various reagents to react with samples to enhance specificity, facilitate detection, and improve the accuracy and repeatability of results.

[0003] After the reagent is used up, the process usually needs to be stopped to replace the reagent, and the pipeline needs to be refilled to prevent air bubbles in the pipeline from affecting the reagent filling volume, thereby affecting the detection results. Refilling the pipeline also causes waste of reagents. Summary of the Utility Model

[0004] The purpose of the utility model is to provide an online reagent replacement device without loss, which meets the requirements of online reagent replacement without loss for medical IVD devices, and has the advantages of simple structure, high reagent adding progress, no loss, and low cost.

[0005] To achieve the above purpose, the utility model provides an online reagent replacement device without loss, which includes a control unit, a liquid circuit unit and an adjustment unit; the control unit includes a metering pump, a first three-way valve and a second three-way valve, one end of the first three-way valve is connected to the metering pump, one port of the second three-way valve is fixedly connected to the metering pump, the other two ports of the second three-way valve are respectively connected to external positive and negative air pressures, the liquid circuit unit is connected to the first three-way valve, and the adjustment unit is connected to the liquid circuit unit.

[0006] Among them, the liquid circuit unit includes a reagent tube and a reagent cup, the reagent tube is connected to one port of the first three-way valve, the reagent cup is detachably connected to the reagent tube and is located at one end of the reagent tube far from the first three-way valve.

[0007] Among them, the liquid circuit unit further includes a buffer tube, a buffer cup and a sensor, the buffer tube is connected to another port of the first three-way valve, the buffer cup is connected to the buffer tube and is located at one end of the buffer tube far from the first three-way valve, the number of sensors is two, and the two sensors are respectively fixedly connected to the buffer cup and are respectively located at the upper and lower ends of the buffer cup.

[0008] Among them, the adjustment unit includes an adjustment tube and a first two-way valve, the adjustment tube is connected to the buffer cup, and one port of the first two-way valve is fixedly connected to the adjustment tube.

[0009] Among them, the adjusting unit further includes a connecting pipe, a reagent bottle, and a second two-way valve. The connecting pipe is connected to the buffer cup. The reagent bottle is detachably connected to the connecting pipe and is located at one end of the connecting pipe away from the reagent cup. The second two-way valve is detachably connected to the connecting pipe and is located between the reagent bottle and the buffer cup.

[0010] For an online lossless reagent replacement device of the present utility model, when adding reagents quantitatively, the second three-way valve is connected to negative pressure, driving the metering pump to pump the reagent in the buffer cup into the metering pump. Then, the second three-way valve is connected to positive pressure, and the port of the first three-way valve leading to the reagent pipe is opened. The metering pump pumps the reagent through the reagent pipe into the reagent cup, achieving the purpose of completing the reagent addition, meeting the requirement of online lossless reagent replacement for medical IVD devices, and having the advantages of simple structure, high reagent addition progress, no loss, and low cost. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art.

[0012] Figure 1 is a schematic diagram of an online lossless reagent replacement device according to the first embodiment of the present utility model.

[0013] Figure 2 is a schematic diagram of an online lossless reagent replacement device according to the second embodiment of the present utility model.

[0014] In the figure: 101 - metering pump, 102 - first three-way valve, 103 - second three-way valve, 104 - reagent pipe, 105 - reagent cup, 106 - buffer pipe, 107 - buffer cup, 108 - sensor, 201 - adjusting pipe, 202 - first two-way valve, 203 - connecting pipe, 204 - reagent bottle, 205 - second two-way valve. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0015] The following details the embodiments of the present utility model. The examples of the embodiments are shown in the drawings. The embodiments described below with reference to the drawings are exemplary and are intended to explain the present utility model and should not be construed as a limitation to the present utility model.

[0016] The first embodiment of the present application is as follows:

[0017] Please refer to Figure 1 , among which, Figure 1It is the schematic diagram of an on-line lossless reagent replacement device according to the first embodiment of the present utility model. The present utility model provides an on-line lossless reagent replacement device, which includes a control unit and a liquid path unit. The control unit includes a metering pump 101, a first three-way valve 102 and a second three-way valve 103. The liquid path unit includes a reagent tube 104, a reagent cup 105, a buffer tube 106, a buffer cup 107 and a sensor 108. Through the foregoing solution, the requirement of on-line lossless reagent replacement for medical IVD devices is met, and the structure is simple, the reagent adding progress is high, there is no loss, and the cost is low.

[0018] For this specific embodiment, one end of the first three-way valve 102 is connected to the metering pump 101. One port of the second three-way valve 103 is fixedly connected to the metering pump 101. The other two ports of the second three-way valve 103 are respectively connected to the external positive and negative air pressures. The liquid path unit is connected to the first three-way valve 102. The adjustment unit is connected to the liquid path unit. The metering pump 101 is driven by positive and negative air pressures. Through the opening cooperation of the second three-way valve 103, the metering pump 101 is driven by positive and negative air pressures. When negative pressure is applied, the reagent is inhaled, and when positive pressure is applied, the reagent is discharged.

[0019] Among them, the reagent tube 104 is connected to one port of the first three-way valve 102. The reagent cup 105 is detachably connected to the reagent tube 104 and is located at the end of the reagent tube 104 away from the first three-way valve 102. When adding reagent quantitatively, the second three-way valve 103 is applied with negative pressure, driving the metering pump 101 to pump the reagent in the buffer cup 107 into the metering pump 101. Then the second three-way valve 103 is applied with positive pressure, and the port of the first three-way valve 102 leading to the reagent tube 104 is opened. The metering pump 101 pumps the reagent into the reagent cup 105 through the reagent tube 104 to achieve the purpose of completing the reagent addition.

[0020] Secondly, the buffer tube 106 is connected to another port of the first three-way valve 102. The buffer cup 107 is connected to the buffer tube 106 and is located at one end of the buffer tube 106 away from the first three-way valve 102. The number of the sensors 108 is two. The two sensors 108 are fixedly connected to the buffer cup 107 and are respectively located at the upper and lower ends of the buffer cup 107. The buffer cup 107 is used to cache the reagent. The reagent is added from the middle of the buffer cup 107 and discharged from the bottom of the buffer cup 107, preventing air bubbles from entering the metering pump 101. When there are air bubbles in the reagent, the air is exhausted through the outlet above the buffer cup 107, avoiding the air bubbles generated when filling the reagent. The sensor 108 is a liquid level monitoring sensor. When the sensor 108 below the buffer cup 107 detects that the liquid level is low, the buffer cup 107 is filled with the reagent. When the sensor 108 above the buffer cup 107 detects that the liquid level is high, the filling of the reagent into the buffer cup 107 is stopped.

[0021] When using the on-line lossless reagent replacement device of this embodiment, when adding reagent quantitatively, the second three-way valve 103 is connected to negative pressure, driving the metering pump 101 to pump the reagent in the buffer cup 107 into the metering pump 101. Then the second three-way valve 103 is connected to positive pressure, and the port of the first three-way valve 102 leading to the reagent tube 104 is connected. The metering pump 101 pumps the reagent into the reagent cup 105 through the reagent tube 104, achieving the purpose of completing the reagent filling, meeting the requirement of on-line lossless reagent replacement for medical IVD equipment, and having the advantages of simple structure, high reagent adding progress, no loss, and low cost.

[0022] The second embodiment of this application is as follows:

[0023] On the basis of the first embodiment, please refer to Figure 2 , where Figure 2 is the schematic diagram of an on-line lossless reagent replacement device according to the second embodiment of the present utility model.

[0024] The on-line lossless reagent replacement device of this embodiment further includes an adjustment unit. The adjustment unit includes an adjustment tube 201, a first two-way valve 202, a connecting tube 203, a reagent bottle 204, and a second two-way valve 205.

[0025] For this specific embodiment, the adjustment tube 201 is connected to the buffer cup 107. One port of the first two-way valve 202 is fixedly connected to the adjustment tube 201. The first two-way valve 202 is communicated with the external atmospheric pressure. The adjustment tube 201 and the first two-way valve 202 are used to exhaust the buffer cup 107.

[0026] Among them, the connecting pipe 203 is connected to the buffer cup 107. The reagent bottle 204 is detachably connected to the connecting pipe 203 and is located at one end of the connecting pipe 203 away from the buffer cup 107. The second two-way valve 205 is detachably connected to the connecting pipe 203 and is located between the reagent bottle 204 and the buffer cup 107. The reagent bottle 204 is used to store reagents. When filling the buffer cup 107 with reagents, the second two-way valve 205 is opened, and the second three-way valve 103 is connected to negative pressure to draw the reagents in the reagent bottle 204 into the buffer cup 107 to complete one filling. The filling operation is repeatedly performed multiple times. When the liquid level of the reagent rises to the position of the upper sensor 108, it is considered that the reagents in the reagent bottle 204 are sufficient. When the filling times reach the set number of times and the liquid level of the reagent fails to rise to the upper sensor 108, it is considered that the reagents in the reagent bottle 204 are insufficient, and the system gives a prompt to replace the reagents. At this time, the remaining reagents in the buffer cup 107 can meet the required reagent dosage for the positive test samples of the instrument, and the reagent can be directly replaced without stopping the machine.

[0027] When using the online lossless reagent replacement device of this embodiment to fill the buffer cup 107 with reagents, the second two-way valve 205 is opened, and the second three-way valve 103 is connected to negative pressure to draw the reagents in the reagent bottle 204 into the buffer cup 107 to complete one filling. The filling operation is repeatedly performed multiple times. When the liquid level of the reagent rises to the position of the upper sensor 108, it is considered that the reagents in the reagent bottle 204 are sufficient. When the filling times reach the set number of times and the liquid level of the reagent fails to rise to the upper sensor 108, it is considered that the reagents in the reagent bottle 204 are insufficient, and the system gives a prompt to replace the reagents. At this time, the remaining reagents in the buffer cup 107 can meet the required reagent dosage for the positive test samples of the instrument, and the reagent can be directly replaced without stopping the machine.

[0028] The above-disclosed are only one or more preferred embodiments of the present application, and the scope of rights of the present application cannot be limited thereby. Those of ordinary skill in the art can understand the entire or partial processes of implementing the above embodiments, and the equivalent changes made according to the claims of the present application still fall within the scope covered by the present application.

Claims

1. An online non-loss reagent replacement device, characterized in that: It includes a control unit, a fluid circuit unit and a regulating unit; The control unit includes a metering pump, a No. 1 three-way valve and a No. 2 three-way valve, one end of the No. 1 three-way valve is connected to the metering pump, one port of the No. 2 three-way valve is fixedly connected to the metering pump, and the other two ports of the No. 2 three-way valve are respectively connected to external positive and negative air pressures, the liquid circuit unit is connected to the No. 1 three-way valve, and the regulating unit is connected to the liquid circuit unit.

2. An online non-loss reagent replacement device as claimed in claim 1, characterized in that: The liquid circuit unit includes a reagent tube and a reagent cup. The reagent tube is connected to one port of the No. 1 three-way valve. The reagent cup is detachably connected to the reagent tube and is located at one end of the reagent tube away from the No. 1 three-way valve.

3. An online non-loss reagent replacement device as claimed in claim 2, characterized in that: The liquid circuit unit also includes a buffer tube, a buffer cup and a sensor. The buffer tube is connected to the other port of the No. 1 three-way valve. The buffer cup is connected to the buffer tube and is located at one end of the buffer tube away from the No. 1 three-way valve. There are two sensors. The two sensors are fixedly connected to the buffer cup and are located at the upper and lower ends of the buffer cup.

4. An online non-loss reagent replacement device as claimed in claim 3, characterized in that: The regulating unit comprises a regulating tube and a No. 1 two-way valve, the regulating tube is connected to the buffer cup, and one port of the No. 1 two-way valve is fixedly connected to the regulating tube.

5. An online non-loss reagent replacement device as claimed in claim 4, characterized in that: The regulating unit also includes a connecting pipe, a reagent bottle and a No. 2 two-way valve, the connecting pipe is connected to the buffer cup, the reagent bottle is detachably connected to the connecting pipe and is located at one end of the connecting pipe away from the reagent bottle, and the No. 2 two-way valve is detachably connected to the connecting pipe and is located between the reagent bottle and the buffer cup.

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