Nano-liter pipetting workstation

Abstract

The utility model relates to the technical field of laboratory instruments, in particular to a nano-liter pipetting workstation. A nano-liter pipetting work station comprises a work box and a pipetting suction head, the pipetting suction head is located in the work box, a mechanical arm connecting piece is arranged in the work box and used for being detachably connected with a mechanical arm, and the end, away from the mechanical arm connecting piece, of the mechanical arm is used for being connected with the pipetting suction head. The mechanical arm connecting piece is connected to the working box in the working box in a positionable reciprocating sliding mode in multiple directions. The working station has the following effects that in the multi-direction positionable reciprocating sliding process in the working box, the mechanical arm connecting piece drives the mechanical arm and the pipetting suction head to do multi-direction positionable reciprocating sliding in the working box, the automation degree of the working station is improved, and the working efficiency is improved.

Description

Technical Field

[0001] This application relates to the technical field of laboratory instruments, and in particular to a nanoliter pipetting workstation. Background Art

[0002] As disclosed in the Chinese utility model patent with the authorization announcement number CN220919272U, a pipetting module and a pipetting workstation having the pipetting module are disclosed, including: a first sliding block connected to a pipette push rod, and by sliding the first sliding block on an optical axis, the pipette assembly sucks liquid, discharges liquid, and retracts the Tip head; a second sliding block connected to the pipette body, and by moving the second sliding block on the optical axis, the pipette assembly picks up the Tip head and the pipette body moves up and down. In this application, through the detachable connection between the second sliding block and the pipette body, different ranges of pipettes and pipettes with different numbers of channels can be adapted by replacing the pipette body. By arranging a motor at the top of the gantry and arranging a motion module inside the gantry, the distance between the motor and the motion structure is increased, and the motion space is increased.

[0003] However, due to the relatively limited movement trajectory of the pipette, it is necessary for the operator to assist in adjusting the position of the pipette, which is rather troublesome and the work efficiency is low. Summary of the Utility Model

[0004] In order to improve the automation degree of the workstation and improve the work efficiency, this application provides a nanoliter pipetting workstation.

[0005] A nanoliter pipetting workstation provided by this application adopts the following technical solution: including a working box and a pipetting tip, the pipetting tip is located inside the working box, a manipulator connecting piece is arranged inside the working box, the manipulator connecting piece is used for detachably connecting a manipulator, one end of the manipulator far from the manipulator connecting piece is used for connecting with the pipetting tip, and the manipulator connecting piece is reciprocally slidably connected to the working box in multiple directions and can be positioned inside the working box.

[0006] By adopting the above technical solution, during the process of the manipulator connecting piece reciprocally sliding in multiple directions and being positionable inside the working box, it drives the manipulator and the pipetting tip to reciprocally slide in multiple directions and be positionable inside the working box, improving the automation degree of the workstation and the work efficiency.

[0007] Preferably, a plurality of driving mechanisms are arranged inside the working box, and the plurality of driving mechanisms are respectively arranged at different positions around the manipulator connecting piece, and the driving mechanisms are used for driving the manipulator connecting piece to reciprocally slide in multiple directions and be positionable to the working box.

[0008] By adopting the above technical solution, it is relatively convenient that a plurality of driving mechanisms located at different positions of the manipulator connecting piece work to drive the pipetting tip to slide at different positions in the working box.

[0009] Preferably, three driving mechanisms are provided. The three driving mechanisms are an X-direction driving mechanism, a Y-direction driving mechanism, and a Z-direction driving mechanism respectively. The X-direction driving mechanism is arranged on one side of the manipulator connecting piece along the X-direction coordinate and is used to drive the manipulator connecting piece to reciprocate slidably and positionably along the X direction. The Y-direction driving mechanism is arranged on one side of the manipulator connecting piece along the Y-direction coordinate and is used to drive the manipulator connecting piece to reciprocate slidably and positionably along the Y direction. The Z-direction driving mechanism is arranged on one side of the manipulator connecting piece along the Z-direction coordinate and is used to drive the manipulator connecting piece to reciprocate slidably and positionably along the Z direction.

[0010] By adopting the above technical solution, the X-direction driving mechanism drives the manipulator connecting piece to reciprocate slidably and positionably along the X direction, the Y-direction driving mechanism drives the manipulator connecting piece to reciprocate slidably and positionably along the Y direction, and the Z-direction driving mechanism drives the manipulator connecting piece to reciprocate slidably and positionably along the Z direction.

[0011] Preferably, a hole plate placement platform is further arranged in the working box. A plurality of placement areas are arranged on the hole plate placement platform, and the plurality of placement areas are evenly distributed on the hole plate placement platform. The placement areas are used to place different hole plates.

[0012] By adopting the above technical solution, different hole plates are placed on different placement areas, and in cooperation with the reciprocating sliding of the manipulator connecting piece driving the pipetting tip in the X direction, Y direction, and Z direction, the pipetting work of different hole plates is realized.

[0013] Preferably, observation ports are symmetrically opened on the two side walls of the working box, and two side transparent plates are arranged on the working box. The two side transparent plates are respectively used to seal the two observation ports.

[0014] By adopting the above technical solution, the side transparent plates facilitate the operator to observe the working condition of the pipetting tip in the working box.

[0015] Preferably, four fixing bars are arranged on each placement area, and the four fixing bars are arranged in a rectangle on the hole plate placement platform, and the four fixing bars respectively abut against the four side walls of the hole plate.

[0016] By adopting the above technical solution, the four fixing bars respectively abut against the four side walls of the hole plate, so that the hole plate is fixed on the hole plate placement platform.

[0017] Preferably, a recycling box is provided on the orifice plate placing platform. The recycling box is located on one side of the placing area and is detachably connected to the orifice plate placing platform in a slidable manner.

[0018] By adopting the above technical solution, the recycling box is used to recycle the discarded pipette tips. After the recycling box is filled with the discarded pipette tips, the recycling box can be slid off the orifice plate placing platform.

[0019] Preferably, an operation opening is provided on the front side of the working box, and a front panel flip cover is provided on the working box. The front panel flip cover is used to seal the operation opening, and the upper end of the front panel flip cover is rotatably connected to the upper side wall of the operation opening.

[0020] By adopting the above technical solution, the front panel flip cover can be rotated and opened to facilitate the operator to repair the components in the working box and to supplement the pipetting liquid.

[0021] In summary, the present application includes at least one of the following beneficial technical effects:

[0022] 1. Driving the manipulator and the pipette tip to reciprocate and slide in multiple directions and be positionable in the working box, improving the automation degree of the workstation and the working efficiency;

[0023] 2. Facilitating the operator to observe the working conditions of the pipette tips in the working box. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 is the overall structure schematic diagram of the present application;

[0025] Figure 2 is the partial structure schematic diagram of the present application;

[0026] Figure 3 is the exploded schematic diagram of the partial structure of the present application;

[0027] Figure 4 is Figure 2 the partial enlarged schematic diagram of part A in

[0028] Description of the reference numerals: 11, working box; 111, operation opening; 112, front panel flip cover; 113, telescopic support rod; 114, observation port; 115, side transparent plate; 116, orifice plate placing platform; 117, slide table support plate; 118, mounting plate; 119, placing area; 12, pipette tip; 121, 96-well plate; 122, TP head box; 123, reagent kit; 124, fixing strip; 125, recycling box; 13, manipulator connecting piece; 141, X-direction driving mechanism; 142, Y-direction driving mechanism; 143, Z-direction driving mechanism; 144, slider. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0029] The present application will be further described in detail below with reference to the accompanying drawings.

[0030] The present application discloses a nanoliter pipetting workstation, which is used to improve the automation degree of the workstation and improve work efficiency.

[0031] Reference Figure 1 、 Figure 2 As shown in FIGS.

[0032] Further, as shown in FIGS. Figure 1 、 Figure 3 a nanoliter pipetting workstation further includes a pipetting tip 12. The pipetting tip 12 is located inside the working box 11. A manipulator connecting member 13 is arranged inside the working box 11. The manipulator connecting member 13 is used for detachably connecting to a manipulator. The end of the manipulator away from the manipulator connecting member 13 is used to connect to the pipetting tip 12. In this embodiment, a well plate placement platform 116 is further arranged inside the working box 11. A plurality of placement areas 119 are arranged on the well plate placement platform 116. The plurality of placement areas 119 are evenly distributed on the well plate placement platform 116. The placement areas 119 are used for placing different well plates. The manipulator connecting member 13 is reciprocally slidably connected to the working box 11 in multiple directions inside the working box 11. Different well plates are placed on different placement areas 119. During the process of the manipulator connecting member 13 reciprocally sliding in multiple directions and being positionable inside the working box 11, the manipulator and the pipetting tip 12 are driven to reciprocally slide in multiple directions and be positionable inside the working box 11, realizing the pipetting work for different well plates, improving the automation degree of the workstation and improving work efficiency.

[0033] Specifically, as shown in FIGS. Figure 1 、 Figure 4, a plurality of driving mechanisms are arranged in the working box 11. The plurality of driving mechanisms are respectively arranged at different positions around the manipulator connecting member 13. The driving mechanisms are used to drive the manipulator connecting member 13 to be reciprocally slidably connected to the working box 11 in multiple directions and be positionable. In this embodiment, three driving mechanisms are provided, namely an X-direction driving mechanism 141, a Y-direction driving mechanism 142, and a Z-direction driving mechanism 143. The X-direction driving mechanism 141 is arranged on one side of the manipulator connecting member 13 along the X-axis coordinate, and the X-direction driving mechanism 141 is used to drive the manipulator connecting member 13 to reciprocally slide in the X direction and be positionable. The Y-direction driving mechanism 142 is arranged on one side of the manipulator connecting member 13 along the Y-axis coordinate, and the Y-direction driving mechanism 142 is used to drive the manipulator connecting member 13 to reciprocally slide in the Y direction and be positionable. The Z-direction driving mechanism 143 is arranged on one side of the manipulator connecting member 13 along the Z-axis coordinate, and the Z-direction driving mechanism 143 is used to drive the manipulator connecting member 13 to reciprocally slide in the Z direction and be positionable. Among them, the X-direction driving mechanism 141 and the Y-direction driving mechanism 142 are linear motors, and the Z-direction driving mechanism 143 is a servo motor. A circle of slide table support plates 117 is circumferentially arranged inside the working box 11. The X-direction driving mechanism 141 and the Y-direction driving mechanism 142 are arranged on the slide table support plates 117. The Z-direction driving mechanism 143 is arranged on the slider 144 of the X-direction driving mechanism 141 through a mounting plate 118. The X-direction driving mechanism 141 drives the manipulator connecting member 13 to reciprocally slide in the X direction and be positionable. The Y-direction driving mechanism 142 drives the manipulator connecting member 13 to reciprocally slide in the Y direction and be positionable. The Z-direction driving mechanism 143 drives the manipulator connecting member 13 to reciprocally slide in the Z direction and be positionable.

[0034] Reference Figure 1 , Figure 3 , in this embodiment, a total of six placement areas 119 are provided on the orifice plate placement platform 116. The six placement areas 119 are arranged in three columns and two rows. In this embodiment, different orifice plates, such as 96-well plates 121, etc., are placed in the placement areas 119, and different TP head boxes 122 and reagent kits 123 are also placed. Four fixing bars 124 are arranged on each placement area 119. The four fixing bars 124 are arranged in a rectangle on the orifice plate placement platform 116, and the four fixing bars 124 respectively abut against the four side walls of the orifice plate or the TP head box 122 or the reagent kit 123.

[0035] Furthermore, a recycling box 125 is arranged on the orifice plate placement platform 116. The recycling box 125 is located on one side of the placement area 119. The recycling box 125 is slidably detachably connected to the orifice plate placement platform 116. The recycling box 125 is used to recycle the waste pipette tips 12. When the recycling box 125 is filled with the waste pipette tips 12, the recycling box 125 can be slid off the orifice plate placement platform 116.

[0036] The implementation principle of a nanoliter pipetting workstation according to an embodiment of the present application is as follows: Different well plates, different TP head boxes 122, and different reagent kits 123 are provided on the well plate placement platform 116. During the process that the X-direction driving mechanism 141, the Y-direction driving mechanism 142, and the Z-direction driving mechanism 143 drive the manipulator connecting member 13 to reciprocally slide in multiple directions and be positionable within the working box 11, the manipulator and the pipetting tip 12 are driven to reciprocally slide in multiple directions and be positionable within the working box 11, so as to implement the pipetting work for different well plates, different TP head boxes 122, and different reagent kits 123, improving the automation degree of the workstation and the working efficiency.

[0037] The embodiments of the specific implementation manners are all preferred embodiments of the present application, and do not limit the protection scope of the present application accordingly. Therefore, all equivalent changes made according to the structure, shape, and principle of the present application shall be covered within the protection scope of the present application.

Claims

1. A nanoliter pipetting workstation, comprising a working box (11) and a pipetting tip (12), wherein the pipetting tip (12) is located in the working box (11), characterized in that: A manipulator connecting piece (13) is arranged in the working box (11), and the manipulator connecting piece (13) is used to be detachably connected to a manipulator, and an end of the manipulator away from the manipulator connecting piece (13) is used to be connected to the pipette tip (12), and the manipulator connecting piece (13) is connected to the working box (11) in a reciprocating sliding manner that can be positioned in multiple directions in the working box (11).

2. A nanoliter liquid transfer workstation according to claim 1, characterized in that: A plurality of drive mechanisms are arranged in the working box (11), and the plurality of drive mechanisms are respectively arranged at different positions around the manipulator connecting member (13), and the drive mechanisms are used to drive the manipulator connecting member (13) to be connected to the working box (11) in a reciprocating sliding manner that can be positioned in multiple directions.

3. A nanoliter liquid transfer workstation according to claim 2, characterized in that: The driving mechanisms are provided in three parts, and the three driving mechanisms are respectively an X-direction driving mechanism (141), a Y-direction driving mechanism (142), and a Z-direction driving mechanism (143). The X-direction driving mechanism (141) is arranged on one side of the manipulator connecting member (13) along the X-direction coordinate, and the X-direction driving mechanism (141) is used to drive the manipulator connecting member (13) to slide back and forth in a positionable manner along the X-direction. The Y-direction driving mechanism (142) is arranged on one side of the manipulator connecting member (13) along the Y-direction coordinate, and the Y-direction driving mechanism (142) is used to drive the manipulator connecting member (13) to slide back and forth in a positionable manner along the Y-direction. The Z-direction driving mechanism (143) is arranged on one side of the manipulator connecting member (13) along the Z-direction coordinate, and the Z-direction driving mechanism (143) is used to drive the manipulator connecting member (13) to slide back and forth in a positionable manner along the Z-direction.

4. A nanoliter liquid transfer workstation according to claim 3, characterized in that: A well plate placement platform (116) is also provided in the working box (11), and a plurality of placement areas (119) are provided on the well plate placement platform (116). The plurality of placement areas (119) are evenly distributed on the well plate placement platform (116), and the placement areas (119) are used to place different well plates.

5. A nanoliter pipetting workstation according to claim 4, characterized in that: Observation ports (114) are symmetrically provided on the box walls on both sides of the working box (11). Two side transparent plates (115) are provided on the working box (11), and the two side transparent plates (115) are respectively used to seal the two observation ports (114).

6. A nanoliter liquid transfer workstation according to claim 5, characterized in that: Four fixing bars (124) are provided on each of the placement areas (119); the four fixing bars (124) are arranged in a rectangular shape on the orifice plate placement platform (116); and the four fixing bars (124) respectively contact four side walls of the orifice plate.

7. A nanoliter liquid transfer workstation according to claim 6, characterized in that: A recovery box (125) is provided on the orifice plate placement platform (116); the recovery box (125) is located on one side of the placement area (119); the recovery box (125) is slidably detachable and connected to the orifice plate placement platform (116).

8. A nanoliter liquid transfer workstation according to claim 7, characterized in that: An operation opening (111) is provided on the front side of the working box (11). A front panel flip cover (112) is provided on the working box (11). The front panel flip cover (112) is used to seal the operation opening (111). The upper end of the front panel flip cover (112) is rotatably connected to the upper side wall of the operation opening (111).

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