Dimethyl sulfoxide micro-reaction small-scale test equipment

Abstract

The utility model relates to the technical field of dimethyl sulfoxide micro-reaction, in particular to dimethyl sulfoxide micro-reaction small-scale test equipment, which is small and exquisite, is convenient for test use, ensures the temperature uniformity and improves the reaction effect. Comprising a microreactor, the bottom of the microreactor is installed on the top of a bottom plate through a supporting assembly, the supporting assembly comprises a plurality of sets of damping supporting rods and a plurality of supporting plates, the outer wall of the microreactor is sleeved with a heat preservation box, the heat preservation box is fixedly connected to the top of the bottom plate, and the left end and the right end of the microreactor are connected with a feeding pipe and a discharging pipe; a water bath assembly is mounted at the bottom of the microreactor and is communicated with the interior of the incubator, and a sealing assembly is connected to the top of the incubator.

Description

Technical Field

[0001] The utility model relates to the technical field of dimethyl sulfoxide micro-reaction, in particular to a dimethyl sulfoxide micro-reaction small-scale test device. Background Art

[0002] Dimethyl sulfoxide is a sulfur-containing organic compound with characteristics such as high polarity, high hygroscopicity, flammability, and high boiling point and non-proticity. Dimethyl sulfoxide is soluble in water, ethanol, acetone, ether, and chloroform, and is a highly polar inert solvent. It is widely used as a solvent and reaction reagent, and has a very high selective extraction ability. It can be used as an extraction solvent for separating alkanes and aromatic hydrocarbons. In the pharmaceutical industry, it can not only be directly used as the raw material and carrier of certain drugs, but also play roles such as anti-inflammatory, analgesic, diuretic, and sedative. Therefore, it is often added as an active ingredient of analgesic drugs to medications. During the production process of dimethyl sulfoxide, the intermediate product dimethyl sulfide is first synthesized, and the intermediate product dimethyl sulfide is further oxidized to obtain the target product dimethyl sulfoxide. Due to the particularity of the oxidation reaction and safety control requirements, the excess of the oxidant and the change of the residence time result in a certain amount of dimethyl sulfoxide being further oxidized to dimethyl sulfone after oxidation. The production device of dimethyl sulfone proposed in the prior art with the publication number CN210030511U is specifically a device for producing dimethyl sulfone by double-tower rectification. The feed pipe is connected to the middle of the mother rectification tower, the bottom of the mother rectification tower is connected to the reboiler, the reboiler is connected to the bottom of the child rectification tower, the top of the child rectification tower is connected to the atomization crystallizer, the atomization crystallizer is connected to the first storage tank, and the bottom of the atomization crystallizer and the first storage tank are respectively connected to the product area through a pipeline after converging, and one way is connected to the upper part of the child rectification tower. The top of the mother rectification tower is connected to the condenser, and the bottom of the condenser is connected to the upper part of the mother rectification tower. However, the device has a large volume, is not convenient for small-scale tests during research and development, and is not convenient for use in the laboratory. Summary of the Utility Model

[0003] In order to solve the above technical problems, the utility model provides a dimethyl sulfoxide micro-reaction small-scale test device with a small size, convenient for test use, ensuring temperature uniformity, and improving the reaction effect.

[0004] A dimethyl sulfoxide micro-reaction pilot test device of the utility model includes a micro-reactor. The bottom of the micro-reactor is installed on the top of a bottom plate through a support assembly. A heat preservation box is sleeved on the outer wall of the micro-reactor, and the heat preservation box is fixedly connected to the top of the bottom plate. The left and right ends of the micro-reactor are connected with a feed pipe and a discharge pipe. A water bath assembly is installed at the bottom of the micro-reactor, and the water bath assembly is internally communicated with the heat preservation box. A sealing assembly is connected to the top of the heat preservation box; materials are input into the micro-reactor through the feed pipe for micro-reaction pilot test. The device is small and convenient for test use. The micro-reactor is heated by water bath through the water bath assembly. The support assembly can ensure comprehensive water bath heating of the micro-reactor. The sealing assembly seals the top of the heat preservation box, which is convenient for overhaul and replacement of the micro-reactor and improves the convenience during use.

[0005] Preferably, the support assembly includes multiple groups of shock-absorbing struts and multiple support plates. Multiple groups of shock-absorbing struts are uniformly fixedly connected to the top of the bottom plate. The top of the shock-absorbing strut is fixedly connected with a support plate. Multiple rectangular holes are arranged on the support plate, and the bottom end of the micro-reactor is located on the top of the support plate; the micro-reactor is supported by the shock-absorbing struts and the support plates, which can make the micro-reactor separated from contact with the top of the bottom plate, increase the water bath area, ensure the temperature uniformity, and improve the reaction effect.

[0006] Preferably, the water bath assembly includes a water tank, multiple support legs, a liquid adding pipe, a partition board, a submersible pump, a water delivery pipe, a water temperature detector, a return pipe, a first heater and a second heater. The water tank is fixedly connected to the bottom of the bottom plate. A liquid adding pipe is connected to the left side wall of the water tank. Support legs are respectively fixedly connected to the four corners of the bottom of the water tank. A partition board is fixedly connected to the inner bottom end of the water tank. The submersible pump is installed in the water tank at the front end of the partition board. The output end of the submersible pump has a water delivery pipe, and the input end of the water delivery pipe is internally communicated with the heat preservation box. The water temperature detector is installed on the front inner wall of the water tank. The input end of the return pipe is communicated with the upper part of the rear side wall of the heat preservation box, and the output end of the return pipe is connected to the rear inner wall of the water tank. The first heater is installed at the inner bottom end of the water tank at the front end of the partition board, and the second heater is installed at the inner bottom end of the water tank at the rear end of the partition board; the bottom plate is supported by the support legs and the water tank. The water bath liquid is added into the water tank through the liquid adding pipe. The water bath liquid is heated by the first heater. The temperature of the water bath liquid is detected by the water temperature detector. The submersible pump is started to input the water bath liquid into the heat preservation box through the water delivery pipe to heat the micro-reactor by water bath. The upper water bath liquid flows back into the rear side of the water tank through the return pipe. The water bath liquid is reheated by the second heater. The heated water bath liquid overflows to the front end of the water tank through the partition board for cyclic use.

[0007] Preferably, a reduction motor is fixedly installed at the lower part of the right side wall of the incubator. The output end of the reduction motor extends into the incubator and is fixedly connected with a wave wheel disc. A second water temperature detector is fixedly connected inside the left side wall of the incubator. Start the reduction motor to drive the wave wheel disc to rotate, stir the water bath solution inside the incubator, and detect the temperature of the water bath solution inside the incubator through the second water temperature detector to ensure that the temperature of the water bath solution in the incubator is evenly distributed and ensure the progress of the reaction.

[0008] Preferably, the sealing assembly includes a cover plate and a sealing ring. A sealing groove is provided at the top end of the incubator. The cover plate is installed on the top end of the incubator, and a sealing ring matching the sealing groove is fixedly connected to the bottom of the cover plate. When in use, the cover plate is installed on the top end of the incubator, driving the sealing ring into the sealing groove, improving the sealing performance of the incubator. Moving the cover plate away from the top of the incubator facilitates the maintenance and replacement of the microreactor, improving the convenience during use.

[0009] Preferably, lead screws are rotatably installed on the outer walls at the left and right ends of the incubator. A limit frame is screwed on the lead screws. The upper part of the limit frame is set as an inclined block. The left and right ends of the top of the cover plate are provided with inclined blocks matching the limit frame. After the cover plate is installed on the top of the incubator, rotate the lead screws to push the limit frame towards the incubator, and through the cooperation of the limit frame and the inclined block, the cover plate is fixedly connected to improve the stability.

[0010] Compared with the prior art, the beneficial effects of the present utility model are as follows: The material is input into the microreactor through the feed pipe for micro reaction small-scale test. The equipment is small and convenient for test use. The microreactor is heated by water bath through the water bath assembly. The support assembly can ensure comprehensive water bath heating of the microreactor. The sealing assembly seals the top of the incubator, facilitating the maintenance and replacement of the microreactor and improving the convenience during use. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 is a structural schematic diagram of the present utility model;

[0012] Figure 2 is an axonometric structural schematic diagram of the present utility model;

[0013] Figure 3 is a front view structural schematic diagram of the present utility model;

[0014] Figure 4 is a front view sectional structural schematic diagram of the present utility model;

[0015] Figure 5 is a right view sectional structural schematic diagram of the present utility model;

[0016] Reference numerals in the drawings: 1, micro-reactor; 2, bottom plate; 3, feed pipe; 4, discharge pipe; 5, shock-absorbing strut; 6, support plate; 7, water tank; 8, support leg; 9, liquid adding pipe; 10, partition board; 11, submersible pump; 12, water delivery pipe; 13, water temperature detector; 14, return pipe; 15, first heater; 16, second heater; 17, second water temperature detector; 18, reduction motor; 19, wave wheel disc; 20, insulation box; 21, cover plate; 22, sealing ring; 23, lead screw; 24, limit frame; 25, inclined block. Detailed implementation mode

[0017] For the convenience of understanding the present utility model, the present utility model will be described more comprehensively below with reference to the relevant drawings. The present utility model can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present utility model more thorough and comprehensive.

[0018] As Figures 1 to 5 shown, multiple groups of shock-absorbing struts 5 are uniformly and fixedly connected to the top of the bottom plate 2. The top of the shock-absorbing strut 5 is fixedly connected with a support plate 6. Multiple rectangular holes are provided on the support plate 6. The bottom end of the micro-reactor 1 is located on the top of the support plate 6. An insulation box 20 is sleeved on the outer wall of the micro-reactor 1. The insulation box 20 is fixedly connected to the top of the bottom plate 2. The left and right ends of the micro-reactor 1 are connected with a feed pipe 3 and a discharge pipe 4. A water tank 7 is fixedly connected to the bottom of the bottom plate 2. A liquid adding pipe 9 is connected to the left side wall of the water tank 7. Support legs 8 are respectively fixedly connected to the four corners of the bottom of the water tank 7. A partition board 10 is fixedly connected to the inner bottom end of the water tank 7. A submersible pump 11 is installed in the water tank 7 at the front end of the partition board 10. The output end of the submersible pump 11 has a water delivery pipe 12. The input end of the water delivery pipe 12 is communicated with the inside of the insulation box 20. A water temperature detector 13 is installed on the front inner wall of the water tank 7. The input end of the return pipe 14 is communicated with the upper part of the rear side wall of the insulation box 20. The output end of the return pipe 14 is connected to the rear inner wall of the water tank 7. A first heater 15 is installed at the inner bottom end of the water tank 7 at the front end of the partition board 10. A second heater 16 is installed at the inner bottom end of the water tank 7 at the rear end of the partition board 10. A reduction motor 18 is fixedly installed at the lower part of the right side wall of the insulation box 20. The output end of the reduction motor 18 extends into the inside of the insulation box 20 and is fixedly connected with a wave wheel disc 19. A second water temperature detector 17 is fixedly connected to the inside of the left side wall of the insulation box 20. A sealing groove is formed at the top end of the insulation box 20. A cover plate 21 is covered on the top end of the insulation box 20. A sealing ring 22 matching the sealing groove is fixedly connected to the bottom of the cover plate 21. Lead screws 23 are rotatably installed on the outer walls of the left and right ends of the insulation box 20. A limit frame 24 is screwed on the lead screw 23. The upper part of the limit frame 24 is an inclined block. Inclined blocks 25 matching the limit frame 24 are installed at the left and right ends of the top of the cover plate 21;

[0019] The material is input into the microreactor 1 through the feed pipe 3 for small-scale microreactions. The equipment is small and compact, facilitating experimental use. The microreactor 1 is supported by the shock-absorbing struts 5 and the support plate 6, enabling the microreactor 1 to be disengaged from contact with the top of the bottom plate 2, increasing the water bath area, ensuring temperature uniformity, and improving the reaction effect. The bottom plate 2 is supported by the legs 8 and the water tank 7. The water bath solution is added into the water tank 7 through the liquid adding pipe 9. The water bath solution is heated by the first heater 15. The temperature of the water bath solution is detected by the water temperature detector 13. The submersible pump 11 is started to input the water bath solution into the insulation box 20 through the water pipe 12 for water bath heating of the microreactor 1. The upper water bath solution flows back to the rear side inside the water tank 7 through the return pipe 14. The water bath solution is reheated by the second heater 16. The heated water bath solution overflows to the front end of the water tank 7 through the partition plate 10 for recycling. The reduction motor 18 is started to drive the wave wheel disc 19 to rotate, agitating the water bath solution inside the insulation box 20. The temperature of the water bath solution inside the insulation box 20 is detected by the second water temperature detector 17 to ensure uniform distribution of the water bath solution temperature inside the insulation box 20 and ensure the progress of the reaction. When in use, the cover plate 21 is installed on the top of the insulation box 20, driving the sealing ring 22 into the sealing groove to improve the sealing performance of the insulation box 20. The cover plate 21 is removed from the top of the insulation box 20 to facilitate the maintenance and replacement of the microreactor 1, improving the convenience during use. After the cover plate 21 is installed on the top of the insulation box 20, the lead screw 23 is rotated to push the limit frame 24 towards the insulation box 20. The cover plate 21 is fixedly connected through the cooperation of the limit frame 24 and the inclined block 25 to improve stability.

[0020] Such as Figures 1 to 5As shown in the figure, a dimethyl sulfoxide micro-reaction pilot test device of the present utility model, when working, materials are input into the micro-reactor 1 through the feed pipe 3 for micro-reaction pilot test. The bottom plate 2 is supported by the legs 8 and the water tank 7. The water bath solution is added into the water tank 7 through the liquid adding pipe 9. The water bath solution is heated by the first heater 15. The temperature of the water bath solution is detected by the water temperature detector 13. The submersible pump 11 is started to input the water bath solution into the heat preservation box 20 through the water delivery pipe 12 to perform water bath heating on the micro-reactor 1. The upper water bath solution flows back to the rear side inside the water tank 7 through the return pipe 14. The water bath solution is reheated by the second heater 16. The heated water bath solution overflows to the front end of the water tank 7 through the partition plate 10 for recycling. The reduction motor 18 is started to drive the wave wheel disc 19 to rotate to stir the water bath solution inside the heat preservation box 20. The temperature of the water bath solution inside the heat preservation box 20 is detected by the second water temperature detector 17 to ensure that the temperature of the water bath solution inside the heat preservation box 20 is evenly distributed to ensure the reaction proceeds. The cover plate 21 is covered on the top of the heat preservation box 20, driving the sealing ring 22 into the sealing groove to improve the sealing performance of the heat preservation box 20. The cover plate 21 is removed from the top of the heat preservation box 20 to facilitate the maintenance and replacement of the micro-reactor 1. After the cover plate 21 is covered on the top of the heat preservation box 20, the lead screw 23 is rotated to push the limit frame 24 towards the heat preservation box 20. Through the cooperation of the limit frame 24 and the inclined block 25, the cover plate 21 is fixedly connected.

[0021] The submersible pump 11, the first heater 15, the second heater 16, the water temperature detector 13, the second water temperature detector 17 and the reduction motor 18 of a dimethyl sulfoxide micro-reaction pilot test device of the present utility model are purchased on the market. Those skilled in the industry only need to install and operate according to the attached operation manuals, without the need for those skilled in the art to perform creative labor.

[0022] The above are only the preferred embodiments of the present utility model. It should be noted that for those of ordinary skill in the art in the technical field, without departing from the technical principle of the present utility model, several improvements and modifications can still be made, and these improvements and modifications should also be regarded as the protection scope of the present utility model.

Claims

1. A dimethyl sulfoxide micro-reaction test equipment, characterized in that: The invention comprises a microreactor (1), wherein the bottom of the microreactor (1) is mounted on the top of a bottom plate (2) via a supporting assembly, an insulation box (20) is mounted on the outer wall of the microreactor (1), the insulation box (20) is fixedly connected to the top of the bottom plate (2), a feed pipe (3) and a discharge pipe (4) are connected to the left and right ends of the microreactor (1), a water bath assembly is mounted on the bottom of the microreactor (1), and the water bath assembly is connected to the inside of the insulation box (20), and a sealing assembly is connected to the top of the insulation box (20).

2. A dimethyl sulfoxide micro-reaction test equipment as claimed in claim 1, characterized in that: The support assembly comprises a plurality of groups of shock-absorbing support rods (5) and a plurality of support plates (6); the plurality of groups of shock-absorbing support rods (5) are evenly fixedly connected to the top of the bottom plate (2); the top of the shock-absorbing support rods (5) is fixedly connected to the support plate (6); a plurality of rectangular holes are arranged on the support plate (6); and the bottom end of the microreactor (1) is located on the top of the support plate (6).

3. A dimethyl sulfoxide micro-reaction test equipment as claimed in claim 1, characterized in that: The water bath assembly comprises a water tank (7), a plurality of legs (8), a liquid adding pipe (9), a partition (10), a submersible pump (11), a water delivery pipe (12), a water temperature detector (13), a return pipe (14), a first heater (15) and a second heater (16); the water tank (7) is fixedly connected to the bottom of the base plate (2); the left side wall of the water tank (7) is connected to the liquid adding pipe (9); the legs (8) are fixedly connected to the four corners of the bottom of the water tank (7); the inner bottom end of the water tank (7) is fixedly connected to the partition (10); and the submersible pump (11) is installed at the front end of the partition (10). A water tank (7) is provided with a water delivery pipe (12) at the output end of a submersible pump (11), the input end of the water delivery pipe (12) is communicated with the interior of a heat preservation box (20), a water temperature detector (13) is mounted on the front inner wall of the water tank (7), the input end of a return pipe (14) is communicated with the upper portion of the rear side wall of the heat preservation box (20), the output end of the return pipe (14) is connected to the rear inner wall of the water tank (7), a first heater (15) is mounted on the bottom end of the interior of the water tank (7) at the front end of a partition (10), and a second heater (16) is mounted on the bottom end of the interior of the water tank (7) at the rear end of the partition (10).

4. A dimethyl sulfoxide micro-reaction test equipment as claimed in claim 1, characterized in that: A reduction motor (18) is fixedly mounted on the lower part of the right side wall of the heat preservation box (20); the output end of the reduction motor (18) extends into the heat preservation box (20) and is fixedly connected to a pulsator (19); and a second water temperature detector (17) is fixedly connected to the left side wall of the heat preservation box (20).

5. A dimethyl sulfoxide micro-reaction test equipment as claimed in claim 1, characterized in that: The sealing assembly comprises a cover plate (21) and a sealing ring (22). A sealing groove is provided at the top of the heat preservation box (20). The cover plate (21) is mounted on the top of the heat preservation box (20). The bottom of the cover plate (21) is fixedly connected with a sealing ring (22) matching the sealing groove.

6. A dimethyl sulfoxide micro-reaction test equipment as claimed in claim 5, characterized in that: A screw rod (23) is rotatably mounted on the outer walls of the left and right ends of the heat preservation box (20), a limit frame (24) is screwed on the screw rod (23), the upper part of the limit frame (24) is arranged as an inclined block, and inclined blocks (25) matching the limit frame (24) are mounted on the left and right ends of the top of the cover plate (21).

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