Cryopreservation box and cryopreservation system

Abstract

The utility model relates to the technical field of cell cryopreservation, and particularly discloses a cryopreservation box and a cryopreservation system. The cryopreservation box comprises a partition plate assembly and a box assembly. The partition plate assembly comprises a plurality of partition plates which are connected in an inserted mode, and the colors of the partition plates are different. The box assembly comprises a box body, label pieces and identification pieces, a containing groove is formed in the top end of the box body in a concave mode, the grid plate assembly is detachably installed in the containing groove and divides the containing groove into a plurality of storage grids, the label pieces are bonded to the surface of the box body, and the label pieces are used for recording information related to the storage grids. The identification pieces are detachably connected to the box body and used for indicating the coordinate positions of the storage grids. According to the cryopreservation box, through the optimal design of the structure, the convenience and reliability of manual retrieval are improved, the flexibility degree of storage grid layout is improved, and automatic identification and verification of sample types are achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of cell cryopreservation, in particular to a cryopreservation box and a cryopreservation system. Background Art

[0002] At present, cryogenic access devices that can achieve automatic access to samples and information management of data have emerged on the market. However, generally, special sample storage containers need to be used in combination. If the old samples in traditional liquid nitrogen tanks are to be transferred to automatic devices, the sample containers need to be replaced. And it is very difficult to operate when replacing the container in the cryopreserved state, making it difficult to achieve automatic whole-box access to old samples, and it may have a negative impact on the sample activity. Moreover, although the rows and columns of existing cryopreservation boxes are provided with coordinate marks, it is still not very convenient to manually confirm the coordinates of samples in the central area, and deviations in rows and columns are likely to occur. At the same time, after the existing cryopreservation boxes are molded, a plurality of compartments are arranged vertically and horizontally inside, with fixed sizes and positions. Each compartment can store a cryopreservation tube or a cryopreservation carrier rod, which results in the fixed layout of the compartments and cannot be flexibly changed according to the sample size or sample classification requirements; if multiple usage scenarios need to be adapted, multiple sets of molds may need to be opened, resulting in a high manufacturing cost. Summary of the Utility Model

[0003] The purpose of the utility model is to provide a cryopreservation box and a cryopreservation system to improve the convenience and reliability of manual retrieval, enhance the flexibility of the storage compartment layout, and achieve automatic identification and verification of sample types.

[0004] To achieve the above purpose, the utility model adopts the following technical solutions:

[0005] A cryopreservation box, comprising a partition board assembly and a box assembly; the partition board assembly includes a plurality of mutually inserted partition boards, and the colors of each partition board are different; the box assembly includes a box body, a label member and an identification member. A receiving groove is recessed at the top end of the box body. The partition board assembly is detachably installed in the receiving groove, and the partition board assembly divides the receiving groove into a plurality of storage compartments. The label member is bonded to the surface of the box body, and the label member is used to record information related to the storage compartments. The identification member is detachably connected to the box body, and the identification member is used to indicate the coordinate positions of the storage compartments.

[0006] As an optional technical solution of the cryopreservation box, a plurality of partition board slots are recessed on the side wall of the receiving groove, and the edge of the partition board is inserted into the partition board slots.

[0007] As an optional technical solution of the cryopreservation box, a plurality of card connection grooves are evenly distributed at intervals on the partition board, and two partition boards are mutually inserted through the two card connection grooves.

[0008] As an alternative technical solution of the cryopreservation box, all the storage cells are arranged in a matrix.

[0009] As an alternative technical solution of the cryopreservation box, all the partition plates in the partition plate assembly extend along the first direction or the second direction, and the partition plates extending along the first direction are inserted into each of the partition plates extending along the second direction.

[0010] As an alternative technical solution of the cryopreservation box, the identification member includes a first coordinate block and a second coordinate block. The first coordinate block is provided with first coordinate information, and the second coordinate block is provided with second coordinate information. According to the first coordinate information and the second coordinate information, the coordinate position of any one of the storage cells can be obtained.

[0011] As an alternative technical solution of the cryopreservation box, a plurality of coordinate block slots are circumferentially provided at the top of the side surface of the box body, and the identification member is detachably inserted into the coordinate block slots.

[0012] As an alternative technical solution of the cryopreservation box, a grasping positioning groove is annularly provided on the side surface of the box body.

[0013] A cryopreservation system includes a storage rack and a plurality of the above-mentioned cryopreservation boxes. All the cryopreservation boxes are placed on the storage rack, and identification information is set on the storage rack. The identification information is used to indicate the coordinate position of the cryopreservation box.

[0014] As an alternative technical solution of the cryopreservation system, the cryopreservation system further includes a visual recognition device, and the visual recognition device is used to retrieve the storage cells according to colors.

[0015] The beneficial effects of the present utility model:

[0016] By setting identification parts, each storage cell on the cryobox has a unique coordinate position, which facilitates the positioning of the operator. Combined with the limitation that the colors of each partition board are different, each storage cell has a significant visual feature corresponding one-to-one with the coordinate position, thus improving the intuitiveness, convenience and reliability of retrieval, reducing the risk of retrieval errors, and ensuring the accuracy of retrieval results. The above improvements make the cryobox easy to cooperate with machine vision and can be applied to automated equipment to realize automatic identification and verification of sample types. Combining the design of several partition boards inserted into each other, the identification parts are detachably connected to the box body, and the partition board assembly is detachably installed in the accommodation groove, the layout of the storage cells in the accommodation groove can be adjusted according to the sample size or sample classification requirements, and the identification parts can also be replaced correspondingly, so as to change the size of the storage cells, the shape of the storage cells or the color of the partition boards surrounding the storage cells, enabling the cryobox to match a variety of application scenarios and reducing the manufacturing cost. The label attached to the box body can be used together with the supporting information management software. By means of entering the sample information and sample coordinates into the system, the information management of the samples is realized, the difficulty of transferring old samples from traditional liquid nitrogen tanks to automated equipment is reduced, and the automated access of old samples is realized.

[0017] The cryo-storage system realizes reliable storage of the cryobox by means of the storage rack, reduces the risk of the storage rack shifting in position due to accidents, ensures the storage capacity of the samples, and combined with the setting of identification information, makes the coordinate position of the cryobox easy to obtain, thus reducing the retrieval difficulty of the cryobox and improving the retrieval efficiency of the cryobox. Description of the Drawings

[0018] Figure 1 is a schematic structural view of a cryobox provided by an embodiment of the present utility model;

[0019] Figure 2 is a schematic structural view of a box body provided by an embodiment of the present utility model;

[0020] Figure 3 is a schematic structural view of a first coordinate block provided by an embodiment of the present utility model;

[0021] Figure 4 is a schematic structural view of a second coordinate block provided by an embodiment of the present utility model;

[0022] Figure 5 is a schematic structural view of a partition board provided by an embodiment of the present utility model;

[0023] Figure 6 is a schematic structural view of a partition board assembly provided by an embodiment of the present utility model;

[0024] Figure 7 It is a schematic structural diagram of a cryopreservation box provided by another embodiment of the present utility model;

[0025] Figure 8 It is a schematic structural diagram of a cryopreservation box provided by yet another embodiment of the present utility model;

[0026] Figure 9 It is a schematic structural diagram of a cryopreservation system provided by an embodiment of the present utility model.

[0027] In the figure:

[0028] 100, partition board; 101, card connection groove;

[0029] 200, box assembly; 210, box body; 211, grasping and positioning groove; 212, coordinate block slot; 213, partition board slot; 220, first information label; 230, first coordinate block; 240, second coordinate block;

[0030] 300, storage cell;

[0031] 400, storage rack. Detailed implementation manners

[0032] Next, the technical solutions of the present utility model will be clearly and completely described in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present utility model, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without making creative efforts shall fall within the protection scope of the present utility model.

[0033] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be construed as a limitation of the present utility model. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance. Among them, the terms "first position" and "second position" are two different positions, and moreover, the first feature being "above", "over" and "on" the second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature has a higher horizontal height than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly below and obliquely below the second feature, or simply indicating that the first feature has a lower horizontal height than the second feature.

[0034] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the terms "installation", "connection", and "coupling" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0035] The embodiments of the present utility model will be described in detail below. The examples of the embodiments are shown in the drawings, in which the same or similar reference numerals represent the same or similar elements or elements with the same or similar functions from beginning to end. The embodiments described below with reference to the drawings are exemplary and are only used to explain the present utility model and should not be construed as a limitation of the present utility model.

[0036] As Figures 1 to 6 shown, this embodiment provides a cryopreservation box, which includes a partition plate assembly and a box assembly 200; the partition plate assembly includes a plurality of mutually inserted partition plates 100, and the colors of each partition plate 100 are different; the box assembly 200 includes a box body 210, a label member, and an identification member. A receiving groove is recessed at the top of the box body 210, and the partition plate assembly is detachably installed in the receiving groove, and the partition plate assembly divides the receiving groove into a plurality of storage cells 300. The label member is adhered to the surface of the box body 210, and the label member is used to record information related to the storage cells 300. The identification member is detachably connected to the box body 210, and the identification member is used to indicate the coordinate positions of the storage cells 300. Among them, one or more cryopreservation carriers can be placed in each storage cell 300 as needed, and the cryopreservation carriers are used as samples for cryopreservation.

[0037] By setting identification components, each storage cell 300 has a unique coordinate position on the cryopreservation box, which facilitates the positioning of operators. Combined with the limitation that the colors of each partition board 100 are different, each storage cell 300 has a significant visual feature corresponding one-to-one with the coordinate position, thereby improving the intuitiveness, convenience and reliability of retrieval, reducing the risk of retrieval errors, and ensuring the accuracy of retrieval results; the above improvements make the cryopreservation box easy to cooperate with machine vision, so that it can be applied to automated equipment to realize the automatic identification and verification of sample types. Combining the design of the mutual plug-in connection of several partition boards 100, the detachable connection of the identification components to the box body 210, and the detachable installation of the partition board assembly in the accommodation groove, the layout of the storage cells 300 in the accommodation groove can be adjusted according to the sample size or sample classification requirements, and the identification components can also be correspondingly replaced, so as to achieve the purpose of changing the size of the storage cells 300, the shape of the storage cells 300 or the color of the partition boards 100 surrounding the storage cells 300, enabling the cryopreservation box to match a variety of application scenarios and reducing the manufacturing cost. The label component attached to the box body 210 can be used together with the supporting information management software. By means of inputting sample information and sample coordinates into the system, the information management of samples is realized, the difficulty of transferring old samples in traditional liquid nitrogen tanks to automated equipment is reduced, and the automatic access of old samples is realized.

[0038] Among them, the sample information and sample coordinates can be input into the system manually or by device scanning.

[0039] In this embodiment, the label component can be a one-dimensional code, a two-dimensional code or an RFID, etc. Specifically, the label component includes a first information label 220 and a second information label. The first information label 220 is adhered to the side surface of the box body 210, and the second information label is adhered to the bottom end of the box body 210.

[0040] In this embodiment, a plurality of partition board slots 213 are recessed on the side wall of the accommodation groove, and the edge of the partition board 100 is inserted into the partition board slots 213. Through the insertion cooperation between the partition board slots 213 and the partition board 100, the detachable installation of the partition board assembly in the accommodation groove is realized, reducing the hidden danger of the relative position deviation of the partition board 100 from the box body 210 due to accidents, and ensuring the long-term stable operation of the cryopreservation box. The setting of a plurality of partition board slots 213 increases the flexibility of the installation of the partition board 100 in the accommodation groove, facilitating the optimization of the layout of the storage cells 300, so that it can be adjusted according to the sample size or sample classification requirements.

[0041] Exemplarily, a plurality of card connection slots 101 are evenly distributed at intervals on the partition plate 100, and two partition plates 100 are inserted into each other through the two card connection slots 101. The arrangement of the card connection slots 101 enables the two partition plates 100 to cross each other, thereby realizing the mutual insertion of the partition plates 100. This enables the partition plate assembly to increase or decrease the number of partition plates 100 according to the usage requirements to adapt to the sizes, classification requirements, and shapes of different samples, and to achieve stable operation of the cryobox in various application scenarios.

[0042] In one embodiment, all the storage cells 300 are arranged in a matrix. The above limitation realizes the full utilization of the space in the accommodation slot, reduces the retrieval difficulty of the storage cells 300, and improves the load-bearing capacity of the cryobox.

[0043] Exemplarily, all the partition plates 100 in the partition plate assembly extend along the first direction or the second direction, and the partition plates 100 extending along the first direction are inserted into each partition plate 100 extending along the second direction. Therefore, the partition plates 100 extending along the second direction are also inserted into each partition plate 100 extending along the first direction.

[0044] Through the layout optimization of all the partition plates 100, all the storage cells 300 are arranged in a matrix to achieve the purpose of defining the specific structure of the partition plate assembly. Specifically, the first direction and the second direction are perpendicular to each other.

[0045] In this embodiment, the identification member includes a first coordinate block 230 and a second coordinate block 240. The first coordinate block 230 is provided with first coordinate information, and the second coordinate block 240 is provided with second coordinate information. According to the first coordinate information and the second coordinate information, the coordinate position of any storage cell 300 can be obtained. Through the arrangement of the first coordinate block 230 and the second coordinate block 240, the coordinate position of each storage cell 300 is determined.

[0046] Specifically, the information marked on the first coordinate block 230 is English letters such as A, B, C..., and the information marked on the second coordinate block 240 is Arabic numerals such as 1, 2, 3, 4.... The coordinates of the storage cell 300 are represented by information such as A1, A2, A3, A4, B1, B2, B3, B4, C1, C2, C3, C4....

[0047] For example, if there are four partition plates 100 extending in the first direction, which are yellow, green, cyan, and white in sequence, and three partition plates 100 extending in the second direction, which are blue, pink, and white in sequence. At this time, the partition plate assembly divides the accommodation cavity into a yellow-blue area, a green-blue area, a cyan-blue area, a white-blue area, a yellow-pink area, a green-pink area, a cyan-pink area, a white-pink area, a yellow-white area, a green-white area, a cyan-white area, and a pink-white area, and each area corresponds one-to-one with the row and column coordinates. The naming of the above areas is determined by the colors of the two partition plates 100 forming a corner in the corresponding storage cell 300. This corner is determined by those skilled in the art according to the actual project, as long as it is ensured that the naming is not repeated. The specific determination method is a conventional technical means in the art and will not be elaborated here.

[0048] As Figure 7 shown, in another embodiment, there are four partition plates 100 arranged in a cross shape, forming nine storage cells 300 and the sizes of each storage cell 300 are not exactly the same.

[0049] As Figure 8 shown, in yet another embodiment, there are two partition plates 100 arranged in an eight shape, forming three storage cells 300 and the sizes of each storage cell 300 are not exactly the same.

[0050] Continuing to refer to Figures 1 to 6 , exemplarily, a plurality of coordinate block slots 212 are circumferentially provided at the top of the side surface of the box body 210, and the identification member is detachably inserted into the coordinate block slots 212.

[0051] Through the insertion fit of the identification member and the coordinate block slots 212, the detachable installation of the identification member on the box body 210 is achieved. The limitation that the coordinate block slots 212 are provided at the top of the side surface of the box body 210 optimizes the layout position of the identification member, enabling the identification member to be as close as possible to the storage cell 300, thereby reducing the difficulty of manually retrieving the coordinate position information.

[0052] Furthermore, a grasping positioning groove 211 is provided around the side surface of the box body 210. During automated access, the external handling device clamps the cryogenic storage box through the grasping positioning groove 211. The above limitation facilitates the grasping and positioning of the cryogenic storage box, realizes the automated whole-box access of the samples, and reduces the handling difficulty of the cryogenic storage box.

[0053] As Figures 1 to 6 and Figure 9 shown, this embodiment also provides a cryogenic storage system, including a storage rack 400 and the above-mentioned cryogenic storage box. All the cryogenic storage boxes are placed on the storage rack 400, and identification information is set on the storage rack 400, and the identification information is used to indicate the coordinate position of the cryogenic storage box.

[0054] The cryopreservation system realizes reliable storage of cryopreservation boxes by means of the storage rack 400, reduces the risk of the storage rack 400 shifting in position accidentally, ensures the storage capacity for samples, and with the setting of identification information, makes the coordinate positions of the cryopreservation boxes easy to obtain, thereby reducing the retrieval difficulty of the cryopreservation boxes and improving the retrieval efficiency of the cryopreservation boxes.

[0055] Specifically, all the cryopreservation boxes are arranged in a matrix.

[0056] In this embodiment, the cryopreservation system further includes a visual recognition device, and the visual recognition device is used to retrieve the storage cells 300 according to colors.

[0057] With the setting of the visual recognition device, the color differentiation of the storage cells 300 can be automatically completed, thereby optimizing the automatic retrieval ability of the cryopreservation system, enhancing the automation degree of the cryopreservation system, reducing the workload of the operators, reducing the probability of retrieval errors, improving the work efficiency, and ensuring the long-term stable operation of the cryopreservation system.

[0058] Obviously, the above embodiments of the present utility model are merely examples for clearly illustrating the present utility model, rather than limiting the implementation manners of the present utility model. For those of ordinary skill in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation manners here. Any modifications, equivalent replacements, and improvements made within the spirit and principle of the present utility model shall be included within the protection scope of the claims of the present utility model.

Claims

1. A freezing box, characterized in that: include: A grid plate assembly comprises a plurality of grid plates (100) plugged into each other, each grid plate (100) having a different color; A box assembly (200) comprises a box body (210), a label member and an identification member, wherein a receiving groove is recessed at the top of the box body (210), the partition plate assembly is detachably mounted in the receiving groove, and the partition plate assembly divides the receiving groove into a plurality of storage cells (300), the label member is adhered to the surface of the box body (210), the label member is used to record information related to the storage cells (300), the identification member is detachably connected to the box body (210), and the identification member is used to indicate the coordinate position of the storage cells (300).

2. The freezing box according to claim 1, characterized in that: A plurality of partition plate slots (213) are recessed on the side wall of the accommodating groove, and the edges of the partition plates (100) are inserted into the partition plate slots (213).

3. The freezing box according to claim 1, characterized in that: A plurality of card connection slots (101) are evenly spaced on the partition plate (100), and two partition plates (100) are plugged into each other via the two card connection slots (101).

4. The freezing box according to claim 1, characterized in that: All the storage cells (300) are arranged in a matrix.

5. The freezing box according to claim 4, characterized in that: All the grid plates (100) in the grid plate assembly extend along the first direction or the second direction, and the grid plates (100) extending along the first direction are plugged into each of the grid plates (100) extending along the second direction.

6. The freezing box according to claim 4, characterized in that: The identification element comprises a first coordinate block (230) and a second coordinate block (240); the first coordinate block (230) is provided with first coordinate information, and the second coordinate block (240) is provided with second coordinate information; and the coordinate position of any storage cell (300) can be obtained based on the first coordinate information and the second coordinate information.

7. The cryopreservation box according to claim 1, characterized in that: A plurality of coordinate block slots (212) are provided in the circumferential direction of the top of the side surface of the box body (210), and the identification piece can be detachably inserted into the coordinate block slots (212).

8. The cryopreservation box according to any one of claims 1 to 7, characterized in that: The side surface of the box body (210) is provided with a grabbing and positioning groove (211).

9. A cryopreservation system, comprising a storage rack (400) and a plurality of cryopreservation boxes according to any one of claims 1 to 8, characterized in that: All of the freezing boxes are placed on the storage rack (400), and identification information is provided on the storage rack (400), and the identification information is used to indicate the coordinate position of the freezing box.

10. The cryopreservation system according to claim 9, characterized in that: The freezing system further comprises a visual recognition device, which is used to retrieve the storage cell (300) according to color.

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