Reaction device for preparing molecular fluorescent probe

Abstract

The utility model discloses a reaction device for preparing a molecular fluorescent probe, which comprises a support plate, an adjusting rod fixedly connected to the outer surface of the top of the support plate, a moving ring slidably connected to the outer surface of the adjusting rod, a funnel sleeved in a limiting ring, a connecting pipe fixedly connected to the bottom of the funnel, and a conical flask arranged below the connecting pipe. The conical flask is placed above the supporting plate; a positioning frame is fixedly connected to the upper surface of the fixing ring, a fixing block is slidably connected to the interior of the positioning frame, a positioning block is rotatably connected to the fixing block, a torsional spring is arranged between the positioning block and the fixing block, and a limiting plate is fixedly connected to the outer surface of the upper portion of the positioning block. According to the reaction device for preparing the molecular fluorescent probe, the positioning block is pressed on the outer surface of the filter paper, so that the position of the filter paper can be fixed, the filter paper cannot move under the driving of the glass rod when a user conducts drainage and filtration, and then liquid is prevented from moving into filtrate from the edge of the funnel; therefore, the purity of the interior of the filtrate is relatively high.

Description

Technical Field

[0001] The utility model relates to the technical field of probe preparation, in particular to a reaction device for preparing a molecular fluorescent probe. Background Art

[0002] Molecular fluorescent probes refer to a class of molecules that use fluorescent signals to identify analytes, thereby achieving qualitative or quantitative analysis of the analytes. Molecular fluorescent probes usually include three parts: fluorescent groups, linking groups, and recognition groups. The preparation steps of molecular fluorescent probes are relatively complicated, and usually they are subjected to reflux, filtration, drying, etc.

[0003] Molecular probes are made by reacting a variety of chemicals. In order to allow the various intermediate products to react fully, they are generally refluxed at a certain temperature. After reflux, the products will proceed to the next step based on the user's probe production requirements. When the user needs liquid, the liquid will be separated into solid and liquid, i.e. filtered.

[0004] Since molecular probes require more precise data, it is necessary to ensure the accuracy of filtration during filtration. However, due to the small holes in the filter paper, a longer filtration time is required. At the same time, the edge of the filter paper cannot be limited. Therefore, when the user is draining and filtering, the glass rod may move the filter paper, causing the edge of the filter paper to lift up, causing the liquid to flow from the edge of the funnel into the filtrate during filtration, reducing the purity of the filtrate, and causing impurities to appear inside the molecular fluorescent probe, thereby affecting the accuracy of the molecular fluorescent probe.

[0005] In view of the above situation, we propose a reaction device for preparing molecular fluorescent probes. Utility Model Content

[0006] The utility model aims to solve the shortcomings in the prior art and proposes a reaction device for preparing a molecular fluorescent probe.

[0007] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0008] A reaction device for preparing a molecular fluorescent probe comprises a support plate, an adjusting rod is fixedly connected to the top outer surface of the support plate, a moving ring is slidably connected to the outer surface of the adjusting rod, a connecting rod is fixedly connected to the outer surface of the moving ring, an end of the connecting rod away from the adjusting rod is fixedly connected to the fixing ring, a limiting ring is fixedly connected to the bottom of the fixing ring, a funnel is sleeved inside the limiting ring, a connecting tube is fixedly connected to the bottom of the funnel, a conical flask is arranged below the connecting tube, and the conical flask is placed above the support plate.

[0009] The upper surface of the fixed ring is fixedly connected with a positioning frame. A fixed block is slidably connected inside the positioning frame. One end of the fixed block close to the funnel is rotatably connected with a positioning block. A torsion spring is arranged between the positioning block and the fixed block. A limiting plate is fixedly connected to the outer surface above the positioning block. One end of the positioning block away from the fixed block is fixedly connected with an inclined plate.

[0010] One end of the positioning frame away from the funnel is rotatably connected through a lead screw. One end of the lead screw close to the fixed block is threadedly connected inside the positioning block.

[0011] Preferably, a chute is formed through the end of the adjusting rod away from the connecting rod. A first limiting block is slidably connected inside the chute. A first screw rod is rotatably connected to the outer surface of the first limiting block away from the connecting rod. The first screw rod is threadedly connected through the inside of the moving ring.

[0012] Preferably, a lower fixing plate is clamped at the bottom of the fixed ring. A spring is fixedly connected to the inner wall of the cavity formed inside the lower fixing plate. The top of the spring is fixedly connected with an upper fixing plate.

[0013] Preferably, a positioning ring is fixedly connected to the outer surface of one side of the lower fixing plate away from the fixed ring. A moving rod is slidably connected inside the positioning ring. A notch is formed through the moving rod. A second limiting block is slidably connected inside the notch.

[0014] Preferably, a second screw rod is rotatably connected to the outer surface of one side of the second limiting block away from the lower fixing plate. The second screw rod is threadedly connected through the inside of the positioning ring.

[0015] Preferably, a groove is formed at the top of the upper end of the moving rod. The groove is used to support a glass rod for drainage.

[0016] Preferably, one end of the torsion spring is clamped on the outer surface of the positioning block, and the other end of the torsion spring is clamped on the outer surface of the fixed block.

[0017] A reaction device for preparing a molecular fluorescence probe proposed by the present utility model has the following beneficial effects: During filtration, the user first rotates the filter paper and lays it on the surface of the funnel. Then, when the screw rod rotates, it drives the fixed block to move. The fixed block drives the positioning block to move to the edge of the positioning frame until there is no external force acting on the torsion spring. As a result, the positioning block rotates under the drive of the torsion spring, causing the lower surface of the inclined plate to press on the outer surface of the filter paper, fixing the position of the filter paper. Thus, when the user performs drainage filtration, the filter paper will not move under the drive of the glass rod, preventing the liquid from moving from the edge of the funnel into the filtrate, and making the purity of the filtrate higher. When the filtration is completed, the user rotates the screw rod to drive the fixed block to move, and then drives the positioning block to move. When putting it away, the user rotates and straightens the positioning block so that the positioning block can be completely retracted into the positioning frame. Therefore, when the user puts away the filter paper after filtration, it will not be blocked by the positioning block, preventing impurities on the surface of the filter paper from falling off and entering the lower filtrate. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is a schematic diagram of the overall external surface structure of the present utility model;

[0019] Figure 2 is a schematic diagram of the overall top structure of the present utility model;

[0020] Figure 3 is an exploded view of the external structure of the fixing ring of the present utility model;

[0021] Figure 4 is of the present utility model Figure 2 enlarged view of part A.

[0022] In the figure: 1, support plate; 2, adjusting rod; 3, chute; 4, moving ring; 5, first limit block; 6, first screw rod; 7, connecting rod; 8, fixing ring; 9, limit ring; 10, funnel; 11, connecting pipe; 12, conical flask; 13, positioning frame; 14, fixed block; 15, screw rod; 16, torsion spring; 17, positioning block; 18, limiting plate; 19, inclined plate; 20, lower fixing plate; 21, spring; 22, upper fixing plate; 23, positioning ring; 24, moving rod; 25, notch; 26, second limit block; 27, second screw rod; 28, groove. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0023] The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments.

[0024] In the description of the present utility model, it should be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation to the present utility model.

[0025] Referring to FIGS. 1-4, a reaction device for preparing a molecular fluorescence probe includes a support plate 1. A regulating rod 2 is fixedly connected to the outer surface of the top of the support plate 1. A moving ring 4 is slidably connected to the outer surface of the regulating rod 2. A connecting rod 7 is fixedly connected to the outer surface of the moving ring 4. One end of the connecting rod 7 far from the regulating rod 2 is fixedly connected to a fixing ring 8. A limiting ring 9 is fixedly connected to the bottom of the fixing ring 8. A funnel 10 is sleeved inside the limiting ring 9. A connecting pipe 11 is fixedly connected to the bottom of the funnel 10. A conical flask 12 is arranged below the connecting pipe 11. A chute 3 is formed through the end of the regulating rod 2 far from the connecting rod 7. A first limiting block 5 is slidably connected to the inside of the chute 3. A first screw rod 6 is rotatably connected to the outer surface of the first limiting block 5 far from the connecting rod 7. The first screw rod 6 is threadedly connected through the inside of the moving ring 4. By rotating the first screw rod 6 by the user, the user can drive the moving ring 4 to move, and thus the user can adjust the position of the funnel 10.

[0026] The conical flask 12 is placed above the support plate 1. A positioning frame 13 is fixedly connected to the upper surface of the fixing ring 8. A fixing block 14 is slidably connected to the inside of the positioning frame 13. A positioning block 17 is rotatably connected to one end of the fixing block 14 close to the funnel 10. A torsion spring 16 is arranged between the positioning block 17 and the fixing block 14. One end of the torsion spring 16 is stuck on the outer surface of the positioning block 17, and the other end of the torsion spring 16 is stuck on the outer surface of the fixing block 14. A limiting plate 18 is fixedly connected to the upper outer surface of the positioning block 17. An inclined plate 19 is fixedly connected to the end of the positioning block 17 far from the fixing block 14. A lead screw 15 is rotatably connected through one end of the positioning frame 13 far from the funnel 10. One end of the lead screw 15 close to the fixing block 14 is threadedly connected to the inside of the positioning block 17. Without external force, the torsion spring 16 can drive the positioning block 17 to stick to the edge of the funnel 10, and thus the filter paper can be fixed.

[0027] The bottom of the fixed ring 8 is clamped with a lower fixing plate 20. The inner wall of the cavity formed inside the lower fixing plate 20 is fixedly connected with a spring 21. The top of the spring 21 is fixedly connected with an upper fixing plate 22. The outer surface of the side of the lower fixing plate 20 away from the fixed ring 8 is fixedly connected with a positioning ring 23. A moving rod 24 is slidably connected inside the positioning ring 23. A notch 25 is formed through the moving rod 24. A second limiting block 26 is slidably connected inside the notch 25. The outer surface of the side of the second limiting block 26 away from the lower fixing plate 20 is rotatably connected with a second screw rod 27. The second screw rod 27 is threadedly connected through the positioning ring 23. A groove 28 is formed at the top of the upper end of the moving rod 24. The groove 28 is used to support a glass rod for drainage. The user rotates the second screw rod 27 so that the moving rod 24 can move inside the positioning ring 23 until the positioning ring 23 can be adjusted to a suitable height, enabling the glass rod to lean against the inside of the groove 28 when the user is draining, making it easier for the user to hold the glass rod for drainage.

[0028] In summary: During the application of the present utility model, when in use, the user first places the conical flask 12 above the support plate 1, and then places the funnel 10 inside the fixed ring 8. Move the conical flask 12 so that the edge of the connecting pipe 11 at the bottom of the funnel 10 fits against the inner wall of the conical flask 12. Then rotate the first screw rod 6 to drive the first limiting block 5 to move, thereby facilitating the user to adjust the position of the funnel 10 so that the connecting pipe 11 of the funnel 10 can be inserted into the conical flask 12, preventing liquid from flowing out of the bottle during solid-liquid separation. The user first rotates the filter paper and then spreads it on the surface of the funnel 10. Then rotate the screw rod 15. The screw rod 15 drives the fixed block 14 to move. The fixed block 14 drives the positioning block 17 to move. The positioning block 17 moves to the edge of the positioning frame 13, enabling the torsion spring 16 to be free from external force. Then the positioning block 17 rotates under the drive of the torsion spring 16, causing the lower surface of the inclined plate 19 to press against the outer surface of the filter paper, fixing the position of the filter paper. Thus, when the user is draining and filtering, the filter paper will not move under the drive of the glass rod, preventing liquid from moving from the edge of the funnel 10 into the filtrate, and making the purity of the filtrate relatively high; when the filtration is completed, the user rotates the screw rod 15 to drive the fixed block 14 to move, thereby driving the positioning block 17 to move. When putting away, the user rotates and straightens the positioning block 17 so that the positioning block 17 can be completely retracted into the positioning frame 13, preventing the used filter paper from being blocked by the positioning block 17 when being put away and preventing impurities on the surface of the filter paper from falling off and entering the lower filtrate.

[0029] The above are only the preferred specific embodiments of the present utility model, but the protection scope of the present utility model is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present utility model, according to the technical solution of the present utility model and its inventive concept, makes equivalent substitutions or changes, and should be covered within the protection scope of the present utility model.

Claims

1. A reaction device for preparing a molecular fluorescent probe, comprising a support plate (1), the top outer surface of the support plate (1) is fixedly connected to an adjusting rod (2), the outer surface of the adjusting rod (2) is slidably connected to a moving ring (4), the outer surface of the moving ring (4) is fixedly connected to a connecting rod (7), the end of the connecting rod (7) away from the adjusting rod (2) is fixedly connected to a fixing ring (8), the bottom of the fixing ring (8) is fixedly connected to a limiting ring (9), the interior of the limiting ring (9) is sleeved with a funnel (10), the bottom of the funnel (10) is fixedly connected to a connecting tube (11), a conical flask (12) is arranged below the connecting tube (11), and the conical flask (12) is placed above the support plate (1), characterized in that: The upper surface of the fixing ring (8) is fixedly connected with a positioning frame (13), the interior of the positioning frame (13) is slidably connected with a fixing block (14), one end of the fixing block (14) close to the funnel (10) is rotatably connected with a positioning block (17), a torsion spring (16) is provided between the positioning block (17) and the fixing block (14), the upper outer surface of the positioning block (17) is fixedly connected with a limiting plate (18), and the end of the positioning block (17) away from the fixing block (14) is fixedly connected with an inclined plate (19); One end of the positioning frame (13) away from the funnel (10) is rotatably connected to a screw rod (15), and one end of the screw rod (15) close to the fixing block (14) is threadedly connected to the inside of the positioning block (17).

2. A reaction device for preparing a molecular fluorescent probe according to claim 1, characterized in that: A sliding groove (3) is provided through one end of the adjusting rod (2) away from the connecting rod (7); a first limit block (5) is slidably connected inside the sliding groove (3); a first limit block (5) is rotatably connected to an outer surface of the first limit block (5) away from the connecting rod (7); and the first screw (6) is threadedly connected to the inside of the moving ring (4).

3. A reaction device for preparing a molecular fluorescent probe according to claim 2, characterized in that: The bottom of the fixing ring (8) is clamped with a lower fixing plate (20), the inner wall of the cavity opened inside the lower fixing plate (20) is fixedly connected with a spring (21), and the top of the spring (21) is fixedly connected with an upper fixing plate (22).

4. A reaction device for preparing a molecular fluorescent probe according to claim 3, characterized in that: A positioning ring (23) is fixedly connected to the outer surface of one side of the lower fixing plate (20) away from the fixing ring (8); a moving rod (24) is slidably connected inside the positioning ring (23); a notch (25) is penetrated through the moving rod (24); and a second limiting block (26) is slidably connected inside the notch (25).

5. A reaction device for preparing a molecular fluorescent probe according to claim 4, characterized in that: The outer surface of the second limit block (26) away from the lower fixing plate (20) is rotatably connected to a second screw rod (27), and the second screw rod (27) penetrates through the interior of the positioning ring (23) and is threadedly connected.

6. A reaction device for preparing a molecular fluorescent probe according to claim 5, characterized in that: A groove (28) is provided at the top of the upper end of the moving rod (24), and the groove (28) is used to support a glass rod for drainage.

7. A reaction device for preparing a molecular fluorescent probe according to claim 1, characterized in that: One end of the torsion spring (16) is clamped on the outer surface of the positioning block (17), and the other end of the torsion spring (16) is clamped on the outer surface of the fixing block (14).

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