Automatic ultraviolet irradiation device for cell photoaging model

Abstract

The utility model relates to an automatic ultraviolet irradiation device for a cell photoaging model. The automatic ultraviolet irradiation device comprises a box body and a cabinet door hinged to the front surface of the box body, the ultraviolet irradiation mechanism is mounted in the box body; the controller is mounted on the front surface of the box body; the ultraviolet irradiation mechanism comprises rotating rods rotationally installed on the two sides of the inner wall of the box body, a driving motor is started to drive the rotating rods to rotate, the rotating rods drive discs to rotate, a plurality of lamp tubes between the two discs rotate, the damaged lamp tubes are rotated to the upper portion, the normally-used lamp tubes are located at the lower portion, and meanwhile the driving motor is started to drive the rotating rods to rotate. The two driving motors are synchronous motors and drive the driving gears to rotate, the surfaces of the driving gears are meshed with the rack parts, the protection plate is pushed to be located between the two discs, used lamp tubes are located below the protection plate, other unused lamp tubes are located above the protection plate, and the unused lamp tubes are protected.

Description

Technical Field

[0001] The utility model relates to the technical field of photoaging simulation equipment, in particular to an ultraviolet automatic irradiation device for a cell photoaging model. Background Technique

[0002] Photoaging is a skin damage process caused by ultraviolet radiation, which can lead to problems such as rough skin, increased wrinkles, and pigmentation. To study the mechanism and preventive measures of photoaging, researchers usually use an ultraviolet irradiation device to irradiate cells to construct a photoaging model. This model can be used to study the effects of ultraviolet rays on cells and evaluate the photoprotective effects of cosmetics, raw materials, etc. Existing cell photoaging test equipment usually uses UVB, UVA, or UVB+UVA light sources to irradiate human epidermal keratinocytes (Hacat cells) to construct a photoaging cell model. In addition, some equipment can simulate different ultraviolet irradiation conditions by adjusting the type and irradiation intensity of the light source and setting the opening and closing time. In the prior art, there are some problems with existing cell photoaging test equipment. First, the light sources of existing phototoxicity test equipment emit light unevenly and cannot select UVB, UVA, or UVB+UVA light sources as needed. In addition, manual lamp replacement is required, which not only increases the complexity and difficulty of the experiment but also may affect the accuracy of the experimental results.

[0003] For example, an authorized patent document with the application number CN202322008502.6 discloses a light aging test chamber, including: a main body module and a storage module. The main body module includes a box body, a first sealing door hinged at the end of the box body, a frame fixed at the top of the box body and communicating with the inner cavity of the box body, a threaded sleeve fixed at the top of the frame and passing through the box body, a movable frame movably arranged in the inner cavity of the box body, a torsion bar rotatably installed at the top of the movable frame and passing through the threaded sleeve, a bottom plate movably fitted in the movable frame, a plurality of lamp tubes installed at the bottom end of the bottom plate, and a placement rack installed on the inner wall of the box body. The box body is used to form a sealed space to avoid being disturbed by the external environment during light aging tests. The first sealing door is used to control the opening and closing of the box body to facilitate the placement and removal of test materials. An observation window is provided on the first sealing door to facilitate the experimenter to observe the material changes in the box body. This light aging test chamber has the advantages of replaceable light sources and strong practicability.

[0004] The above patent has the problems that the light sources of the phototoxicity test equipment emit light unevenly and cannot select UVB, UVA, or UVB+UVA light sources as needed. In addition, manual lamp replacement is required, which not only increases the complexity and difficulty of the experiment but also may affect the accuracy of the experimental results. Therefore, we need to provide an ultraviolet automatic irradiation device for a cell photoaging model. Content of the Utility Model

[0005] The purpose of the present utility model is to provide an ultraviolet automatic irradiation device for a cell photoaging model. The outer shell material of the box body is selected as heat-resistant and waterproof ABS plastic, and the inside is made of radiation-proof material to ensure the safety and stability of the device. The operation interface of the controller is designed to be simple and intuitive, facilitating the experimenter to operate the opening and closing of the device and select the light source. There are multiple groups of lamp tubes inside the box body, which can automatically replace the lamp tubes. By starting the driving motor to drive the rotating rod to rotate, the rotating rod drives the disc to rotate, causing several lamp tubes between the two discs to rotate, turning the damaged lamp tubes to the upper part and the normally used ones to the lower part. At the same time, start the driving motor. The two driving motors are synchronous motors, driving the driving gear to rotate. The surface of the driving gear meshes with the rack part, pushing the protective plate between the two discs, so that the used lamp tubes are located below the protective plate and the unused lamp tubes are located above the protective plate, protecting the unused lamp tubes and solving the problems raised in the above-mentioned background technology.

[0006] To achieve the above object, the present utility model provides the following technical solutions: An ultraviolet automatic irradiation device for a cell photoaging model, comprising:

[0007] A box body, and a cabinet door hinged to the front of the box body;

[0008] An ultraviolet irradiation mechanism installed inside the box body;

[0009] A controller installed on the front of the box body, which is controlled by a microprocessor;

[0010] The ultraviolet irradiation mechanism includes two rotating rods rotatably installed inside the box body. On one side of the two adjacent rotating rods, discs are fixedly installed. Five lamp tubes arranged side by side are installed between the two discs. The lamp tubes include closely cross-arranged UVB and UVA lamp tubes, and the UVB and UVA lamp tubes can be controlled by a sensor combination switch to separately control the single opening of UVB, the single opening of UVA, or the simultaneous opening of UVB and UVA lamp tubes. A driving motor for automatically rotating the rotating rod is installed on one side of the box body, and a protective member for protecting the lamp tubes is arranged inside the box body.

[0011] Preferably, the protective member includes a fixed seat fixedly installed inside the box body. A groove is opened inside the fixed seat, and a protective plate is slidably installed inside the groove. Rack parts are integrally processed on both sides of the top of the protective plate. Driving motors are fixedly installed inside the groove through two mounting seats. The output end of the driving motor is provided with a driving gear, and the surface of the driving gear meshes with the rack part.

[0012] Preferably, a card slot for limiting the protective plate is arranged on one side inside the box body.

[0013] Preferably, ultraviolet sensors are installed at the four corners of the bottom of the box body.

[0014] Preferably, support plates are fixedly installed on both sides of the inner wall of the box body. Circular grooves are formed inside the two support plates. A tray is installed on the tops of the two support plates. A placement groove for installing a 96-well plate is formed on the top of the tray.

[0015] Preferably, support springs are clamped at both sides of the bottom of the tray. The lower ends of the two support springs are clamped with a rectangular frame. A plug rod is fixedly installed inside the rectangular frame. The lower end of the plug rod is adapted to the circular groove. A groove for the rectangular frame to slide is formed at the bottom of the tray.

[0016] Preferably, limiting rings are integrally processed on the surfaces of the two plug rods.

[0017] Preferably, support bars are fixedly installed on both sides of the bottom of the tray. The bottom of the support bar is attached to the top of the support plate.

[0018] Preferably, a cover plate for maintaining the lamp tube is hinged to the top of the box body.

[0019] Preferably, a fan is embedded in one side of the box body.

[0020] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0021] The outer shell material of the box body of the present utility model is selected as high-temperature resistant and waterproof ABS plastic, and the inside is made of radiation-proof material to ensure the safety and stability of the equipment. The operation interface of the controller is designed to be simple and intuitive, which is convenient for experimenters to turn on and off the equipment and select the light source. Among them, there are multiple groups of lamp tubes inside the box body, and the lamp tubes can be automatically replaced. By starting the driving motor to drive the rotating rod to rotate, the rotating rod drives the disc to rotate, so that several lamp tubes between the two discs rotate, and the damaged lamp tube is rotated to the upper part, and the normally used ones are located at the lower part. At the same time, start the driving motor. The two driving motors are synchronous motors, which drive the driving gear to rotate, and the surface of the driving gear meshes with the rack part, pushing the protection plate between the two discs, so that the used lamp tubes are located under the protection plate, and the rest of the unused lamp tubes are located above the protection plate, playing a protective effect on the unused lamp tubes. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 is a three-dimensional structural schematic diagram of the present utility model;

[0023] Figure 2 is a partial three-dimensional structural diagram of the present utility model;

[0024] Figure 3 is a three-dimensional structural diagram of the rectangular frame of the present utility model;

[0025] Figure 4 This is the three-dimensional view of the lamp tube of the present utility model;

[0026] Figure 5 This is the three-dimensional view of the protective part of the present utility model;

[0027] Figure 6 This is the three-dimensional view of the placement groove of the present utility model.

[0028] In the figure: 1, box body; 2, cabinet door; 3, ultraviolet irradiation mechanism; 31, rotating rod; 32, disc; 33, lamp tube; 34, driving motor; 30, protective part; 301, fixed seat; 302, groove body; 303, protective plate; 304, rack part; 305, driving motor; 306, driving gear; 4, controller; 5, card slot; 7, support plate; 8, round groove; 9, tray; 10, support spring; 11, rectangular frame; 12, inserting rod; 13, groove; 14, limiting ring; 15, support bar; 16, cover plate; 17, fan device. Specific embodiments

[0029] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0030] Please refer to Figures 1-6 , the present utility model provides a technical solution: an ultraviolet automatic irradiation device for a cell photoaging model, including:

[0031] A box body 1 and a cabinet door 2 hinged to the front of the box body 1;

[0032] An ultraviolet irradiation mechanism 3 installed inside the box body 1;

[0033] A controller 4 installed on the front of the box body 1, which is controlled by a microprocessor and is used to set a constant dose and automatically turn off after reaching the constant dose;

[0034] The ultraviolet irradiation mechanism 3 includes two rotating rods 31 rotatably mounted inside the box body 1, and a disc 32 is fixedly mounted on each adjacent side of the two rotating rods 31. Five lamp tubes 33 arranged side by side are installed between the two discs 32. 33 includes UVB and UVA lamp tubes arranged closely and crosswise. The UVB and UVA lamp tubes can be controlled by a sensor combination switch to control the UVB single opening, UVA single opening, or simultaneous opening of the UVB and UVA lamp tubes. A driving motor 34 for the rotating rod 31 to rotate and rotate automatically is installed on one side of the box body 1, and a protective member 30 for protecting the lamp tube 33 is arranged inside the box body 1. Through the side-by-side rotating rods, UVB+UVA lamp tubes are assembled on the rotating rods to solve the problem of light uniformity. The switch combination lamp replacement solves the problem of lamp replacement.

[0035] The protective member 30 includes a fixing seat 301 fixedly mounted inside the box body 1, a groove body 302 is provided inside the fixing seat 301, a protective plate 303 is slidably mounted inside the groove body 302, rack parts 304 are integrally processed on both sides of the top of the protective plate 303, a driving motor 305 is fixedly mounted inside the groove body 302 through two mounting seats, a driving gear 306 is mounted on the output end of the driving motor 305, and the surface of the driving gear 306 is meshed with the rack part 304;

[0036] In this embodiment, the shell material of the box body 1 is selected to be high temperature resistant and waterproof ABS plastic, and the interior is made of radiation proof material to ensure the safety and stability of the equipment. The operation interface design of the controller 4 is simple and intuitive, which is convenient for the experimenter to open and close the equipment and select the light source. The lamp tubes 33 are multiple groups inside the box body 1, and the lamp tubes 33 can be automatically replaced. By starting the driving motor 34 to drive the rotating rod 31 to rotate, the rotating rod 31 drives the disc 32 to rotate, so that the several lamp tubes 33 between the two discs 32 rotate, and the damaged lamp tubes are rotated to the top, and the normally used lamp tubes are located at the bottom, and the driving motor 3 is started at the same time. 05. The two driving motors 305 are synchronous motors, which drive the driving gear 306 to rotate. The surface of the driving gear 306 meshes with the rack part 304, pushing the protective plate 303 between the two discs 32, so that the used lamp tube 33 is placed below the protective plate 303, and the other unused lamp tubes 33 are placed above the protective plate 303, which has a protective effect on the unused lamp tubes 33. UVB, UVA, or UVB+UVA light sources can be selected, and the wavelength ranges of the light sources are 280-320nm, 320-400nm, and 280-400nm, respectively, which can be selected as needed. At the same time, the controller 4 can accurately control the opening and closing time of the lamp tube 33, and the time accuracy can reach 0.1 seconds, and the driving motor 34 can be set to a constant speed, and realize uniform light, controllable light source and real-time quantification.

[0037] To lift the other end of the epitaxial protective plate 303, a card slot 5 is provided for the insertion of one end of the protective plate 303, and a card slot 5 for limiting the protective plate 303 is provided on one side inside the box body 1.

[0038] Among them, the box body 1 is internally provided with 4 ultraviolet sensors, which are respectively distributed at the four diagonal positions around the 96-well plate slot to detect the real-time irradiation intensity, with an accuracy of 0.1 mw / cm 2 ;

[0039] Ultraviolet sensors 6 are installed at the four corners of the bottom of the box body 1.

[0040] On both sides of the inner wall of the box body 1, support plates 7 are fixedly installed. Circular grooves 8 are opened inside the two support plates 7. A tray 9 is installed on the tops of the two support plates 7. A placement groove 18 for installing a 96-well plate is opened on the top of the tray 9;

[0041] Specifically, support plates 7 are installed on both sides of the inner wall of the box body 1, and the tray 9 is arranged on the two support plates 7, facilitating the use of the support plates 7 to place objects for the light aging test. A placement groove 18 for conveniently placing a 96-well plate is opened on the top of the tray 9.

[0042] On both sides of the bottom of the tray 9, support springs 10 are clamped. At the lower ends of the two support springs 10, a rectangular frame 11 is clamped. A plug rod 12 is fixedly installed inside the rectangular frame 11. The lower end of the plug rod 12 is adapted to the circular groove 8. A groove 13 for the sliding of the rectangular frame 11 is opened at the bottom of the tray 9;

[0043] Further, when the tray 9 is placed on the two support plates 7, by pressing the two rectangular frames 11, the support springs 10 are compressed, and the plug rod 12 is driven to move upward until the plug rod 12 is inserted into the circular groove 8, limiting the tray 9 on the tops of the two support plates 7 to prevent the tray 9 from being easily pulled off the two support plates 7.

[0044] When the plug rod 12 is inserted into the circular groove 8, a limit ring 14 is arranged on the plug rod 12 to prevent the plug rod 12 from entering the circular groove 8 too deeply. Limit rings 14 are integrally processed on the surfaces of the two plug rods 12.

[0045] On both sides of the bottom of the tray 9, support bars 15 are fixedly installed. The bottoms of the support bars 15 are in contact with the tops of the support plates 7;

[0046] Further, the support bars 15 are arranged at the bottom of the tray 9, and the bottoms of the support bars 15 are in contact with the tops of the support plates 7 to enhance the support effect on the tray 9.

[0047] A cover plate 16 for maintaining the lamp tube 33 is hinged to the top of the box body 1;

[0048] Among them, in order to facilitate the maintenance and repair of the lamp tube 33, a cover body is hinged to the top of the box body 1.

[0049] Specifically, a fan 17 is embedded on one side of the box body 1 to accelerate the ventilation effect inside the box body 1.

[0050] The outer shell material of the box body 1 of this device is selected as high-temperature resistant and waterproof ABS plastic, and the inside is made of radiation-proof material to ensure the safety and stability of the equipment. The operation interface of the controller 4 is designed to be simple and intuitive, which is convenient for the experimenter to turn on and off the equipment and select the light source. Among them, there are multiple groups of lamp tubes 33 inside the box body 1, and the lamp tubes 33 can be automatically replaced. By starting the drive motor 34 to drive the rotating rod 31 to rotate, the rotating rod 31 drives the disc 32 to rotate, so that several lamp tubes 33 between the two discs 32 rotate, and the damaged lamp tube is rotated to the upper part, and the normally used ones are located at the lower part. At the same time, the drive motor 305 is started. The two drive motors 305 are synchronous motors, which drive the drive gear 306 to rotate. The surface of the drive gear 306 meshes with the rack part 304, and the protection plate 303 is pushed between the two discs 32, so that the used lamp tubes 33 are located below the protection plate 303, and the rest of the unused lamp tubes 33 are located above the protection plate 303, playing a protective effect on the unused lamp tubes 33.

[0051] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An automatic ultraviolet irradiation device for a cell photoaging model, characterized in that: include: A box body (1), and a cabinet door (2) hinged on the front side of the box body (1); An ultraviolet irradiation mechanism (3) installed inside the box body (1); A controller (4) installed on the front of the box body (1), wherein the controller (4) is controlled by a microprocessor; The ultraviolet irradiation mechanism (3) comprises two rotating rods (31) rotatably mounted inside the box body (1), a disc (32) being fixedly mounted on one side of the two rotating rods (31), and five lamp tubes (33) arranged side by side being mounted between the two discs (32), the (33) comprising closely cross-arranged UVB and UVA lamp tubes, the UVB and UVA lamp tubes being controllable by a sensor combination switch, respectively controlling the UVB lamp to be turned on alone, the UVA lamp to be turned on alone, or the UVB and UVA lamp tubes to be turned on simultaneously, a driving motor (34) for automatically rotating the rotating rods (31) being mounted on one side of the box body (1), and a protective member (30) for protecting the lamp tubes (33) being arranged inside the box body (1).

2. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 1, characterized in that: The protective member (30) comprises a fixing seat (301) fixedly mounted inside the box body (1); a groove body (302) is provided inside the fixing seat (301); a protective plate (303) is slidably mounted inside the groove body (302); rack portions (304) are integrally machined on both sides of the top of the protective plate (303); a driving motor (305) is fixedly mounted inside the groove body (302) via two mounting seats; a driving gear (306) is mounted on the output end of the driving motor (305); and a surface of the driving gear (306) is meshed with the rack portion (304).

3. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 1, characterized in that: A slot (5) for limiting the position of the protective plate (303) is provided on one side inside the box body (1).

4. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 1, characterized in that: Ultraviolet sensors (6) are installed at the four corners of the bottom of the box body (1).

5. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 1, characterized in that: Support plates (7) are fixedly mounted on both sides of the inner wall of the box body (1), and circular grooves (8) are provided inside the two support plates (7). Trays (9) are mounted on the tops of the two support plates (7), and a placement groove (18) for mounting a 96-well plate is provided on the tops of the trays (9).

6. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 5, characterized in that: Support springs (10) are clamped on both sides of the bottom of the tray (9), and the lower ends of the two support springs (10) are clamped on a rectangular frame (11). An insertion rod (12) is fixedly installed inside the rectangular frame (11), and the lower end of the insertion rod (12) is matched with the circular groove (8). The bottom of the tray (9) is provided with a groove (13) for the rectangular frame (11) to slide.

7. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 6, characterized in that: Limiting rings (14) are integrally processed on the surfaces of the two insertion rods (12).

8. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 5, characterized in that: Support bars (15) are fixedly mounted on both sides of the bottom of the tray (9), and the bottom of the support bar (15) fits with the top of the support plate (7).

9. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 1, characterized in that: A cover plate (16) for maintaining the lamp tube (33) is hingedly connected to the top of the box body (1).

10. The automatic ultraviolet irradiation device for a cell photoaging model according to claim 4, characterized in that: A fan (17) is embedded in one side of the box body (1).

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