Imaging device for immune experiment detection

Abstract

The utility model relates to a medical auxiliary appliance, in particular to an imaging device for immune experiment detection, which comprises a bottom plate (1), an imaging mechanism, a control mechanism (11) and a bearing mechanism, the imaging mechanism and the control mechanism (11) are mounted on the bottom plate (1), and the bearing mechanism is detachably arranged on the bottom plate (1); the imaging mechanism is used for collecting image data after tests, the control mechanism (11) is used for controlling the imaging mechanism to move above the bearing mechanism, data collection is achieved, the microwell plate of the used camera is adjusted according to different experiments, data collection of various experiments is facilitated, and follow-up detection is facilitated.

Description

Technical Field

[0001] The utility model relates to an auxiliary appliance for medical detection, in particular to an imaging device for immunoassay detection. Background Art

[0002] In immunoassay, agglutination tests are common, such as plate agglutination test, micro-agglutination test, hemagglutination test and its hemagglutination inhibition test, as well as dot-iELISA test, ELISpot test and IPMA test, etc. They have a common feature, that is, they produce visible results to the naked eye or recognizable results by instruments. Among them, for the agglutination test and dot-iELISA test, the results are generally judged by the naked eye, which is subjective; while for the ELISpot test and IPMA test, special detection instruments are required. The former requires an ELISpot analyzer for spot counting, and the latter needs to be observed with the naked eye by means of an inverted microscope.

[0003] In the prior art, for the detection after immunoassay, generally an imaging device is used for imaging, and then it is transmitted to a dedicated program for detection. The imaging device used can only perform imaging for a single item and cannot perform imaging for multiple different detection items. Moreover, the imaging results after immunoassay are not clear, resulting in poor detection results.

[0004] Chinese Patent CN 216935736 U discloses an agglutination experiment oscillation mechanism and an agglutination experiment device. Among them, the agglutination experiment oscillation mechanism includes: a driving member, an oscillation assembly and a reaction assembly. A mixed solution is added to the reaction assembly; the output shaft of the driving member is connected to the oscillation assembly, and the oscillation assembly is connected to the reaction assembly, and the oscillation assembly drives the reaction assembly to shake the mixed solution back and forth.

[0005] The technical solution of the utility model improves the detection efficiency of the agglutination experiment.

[0006] The above patent document discloses a single image acquisition mechanism, but it cannot perform imaging for the detection items of multiple immunoassays, and the microplate used is single and cannot perform reactions of multiple immunoassays. In view of this, the utility model provides an imaging device for immunoassay detection, which can perform clear imaging for multiple immune reaction experiments for subsequent detection, and is equipped with a microplate. Content of the Utility Model

[0007] By setting two cameras with different magnification factors and alternately using them for different detection items, the utility model can perform imaging for multiple immunoassays to facilitate subsequent detection. Based on this, the utility model is completed.

[0008] The present utility model provides an imaging device for immune experiment detection, which includes a bottom plate 1, an imaging mechanism, and a reaction carrier mechanism. The imaging mechanism is installed on the bottom plate 1, and the reaction carrier mechanism is arranged in a drawable manner at the middle position between the bottom plate 1 and the imaging mechanism. Through the movement of the imaging mechanism, image data on the reaction carrier mechanism is collected.

[0009] Further, the imaging mechanism includes a plurality of driving components and matching cable carriers, and a camera assembly 9 arranged on one side of the driving components. The driving mechanism includes a first driving component 13 for driving the horizontal movement of the camera assembly 9, and a first cable carrier 2 matching with the first driving component 13 is connected thereto to protect the cables connected to the first driving component 13. It also includes a second driving component 14 for driving the vertical movement of the camera assembly 9, and a second cable carrier 3 matching with the second driving component 14 is connected thereto. The moving track of the second driving component 14 is a first slide rail 4 and a second slide rail 6, and the second driving component 14 is connected to the first slide rail 4 and the second slide rail 6 in a track connection manner; the camera assembly 9 is connected to one side of the first driving component 13 and is flipped through a rotating mechanism arranged at the connection between the first driving component 13 and the camera assembly 9, including a first camera 91 and a second camera 92, and is switched through the rotating mechanism to facilitate the alternating use of the first camera 91 and the second camera 92; the camera assembly 9 is height-adjusted through a lifting mechanism arranged at the connection between the first driving component 13 and the camera assembly 9, and the imaging mechanism is signal-connected to an external detection device.

[0010] Further, the reaction carrier mechanism is arranged at a certain position below the imaging mechanism. Through the movement of the camera assembly 9, image data of the carrier mechanism is collected, including a carrier plate 5 and a plurality of microplate reaction plates 7 arranged on the carrier plate 5. The carrier plate 5 is used to place the microplate reaction plates 7, and the microplate reaction plates 7 carry reaction samples. The microplate reaction plates 7 include a flat microplate reaction plate 71 and a V-shaped microplate reaction plate 72, which are selected according to different reaction samples. The flat microplate reaction plate 71 is provided with flat microholes 701, and the V-shaped microplate reaction plate 72 is provided with V-shaped microholes 702.

[0011] Further, a control mechanism 11 is arranged on one side of the imaging mechanism for controlling the movement of each driving component.

[0012] Further, a light source is arranged below the carrier mechanism to facilitate the camera assembly 9 to collect image data.

[0013] Further, when the carrier plate 5 is placed into the device, a drawer-type connection method is adopted, and a carrier plate handle 8 is arranged at one end close to the outside of the device to facilitate the insertion and removal of the carrier plate 5.

[0014] Furthermore, the outer periphery of the device is covered with a housing 12 to facilitate the use of the device and ensure the safety of its use.

[0015] Furthermore, an ultraviolet lamp 10 is provided on one side of the imaging mechanism. The height of the ultraviolet lamp 10 is higher than that of the imaging mechanism to disinfect the device.

[0016] Compared with the prior art, the technical advantages of an imaging device for immune experiment detection provided by the present utility model are as follows:

[0017] An imaging device for immune experiment detection provided by the present utility model realizes the acquisition of data of multiple immune experiments on one machine by setting two cameras with different focal lengths and alternately using them; by setting microplate reaction plates with different shapes, the application effect of the microplate reaction plates is better, the imaging result is clear, and the accuracy of subsequent detection is improved; by setting an ultraviolet lamp inside the device, it is convenient to disinfect the inside of the device and improve the safety of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is the front view of an imaging device for immune experiment detection according to the present utility model.

[0019] Figure 2 is the top view of an imaging device for immune experiment detection according to the present utility model.

[0020] Figure 3 is the left side view of an imaging device for immune experiment detection according to the present utility model.

[0021] Figure 4 is the schematic diagram of a flat microplate reaction plate of an imaging device for immune experiment detection according to the present utility model.

[0022] Figure 5 is the sectional view of a flat microplate reaction plate of an imaging device for immune experiment detection according to the present utility model.

[0023] Figure 6 is the schematic diagram of a V-shaped microplate reaction plate of an imaging device for immune experiment detection according to the present utility model.

[0024] Figure 7 is the sectional view of a V-shaped microplate reaction plate of an imaging device for immune experiment detection according to the present utility model.

[0025] Figure 8 is an imaging device for immune experiment detection according to the present utility model Figure 7 enlarged view of "A".

[0026] The reference numerals are as follows:

[0027] 1 - Bottom plate; 2 - First drag chain; 3 - Second drag chain; 4 - First slide rail; 5 - Carrier plate; 6 - First slide rail; 7 - Microplate; 8 - Carrier plate handle; 9 - Imaging component; 10 - Ultraviolet lamp; 11 - Control mechanism; 12 - Outer shell; 13 - First driving mechanism; 14 - Second driving mechanism; 71 - Flat microplate; 72 - V-shaped microplate; 701 - Flat micro-holes; 702 - V-shaped micro-holes. Detailed implementation mode

[0028] To further elaborate on the technical means and effects adopted by the present invention to achieve the predetermined utility model purpose, the following combines the drawings and preferred embodiments to detail the specific implementation mode, structure, features and their effects of the present invention as follows.

[0029] Embodiment 1 An imaging device for immunological experiment detection

[0030] As Figures 1-8 shown

[0031] An imaging device for immunological experiment detection, which includes a bottom plate 1, an imaging mechanism, and a reaction carrier mechanism. The imaging mechanism is installed on the bottom plate 1, and the reaction carrier mechanism is arranged in a drawable manner at the intermediate position between the bottom plate 1 and the imaging mechanism. Through the movement of the imaging mechanism, image data on the reaction carrier mechanism is collected.

[0032] The imaging mechanism includes a plurality of driving components and matching drag chains, and an imaging component 9 arranged on one side of the driving component. The driving mechanism includes a first driving component 13 that drives the imaging component 9 to move horizontally, and a first drag chain 2 matching the first driving component 13 is connected thereto to protect the cable connected to the first driving component 13. It also includes a second driving component 14 that drives the imaging component 9 to move vertically, and a second drag chain 3 matching the second driving component 14 is connected thereto. The moving track of the second driving component 14 is the first slide rail 4 and the second slide rail 6, and the second driving component 14 is connected to the first slide rail 4 and the second slide rail 6 in a track connection manner; the imaging component 9 is connected to one side of the first driving component 13 and is flipped through a rotating mechanism arranged at the connection between the first driving component 13 and the imaging component 9, including a first camera 91 and a second camera 92, which are switched through the rotating mechanism to facilitate the alternating use of the first camera 91 and the second camera 92; the imaging component 9 is height-adjusted through a lifting mechanism arranged at the connection between the first driving component 13 and the imaging component 9, and the imaging mechanism is signal-connected to an external detection device.

[0033] The reaction carrier mechanism is arranged at a certain position below the imaging mechanism. Through the movement of the camera assembly 9, image data of the carrier mechanism is collected, including a carrier plate 5 and a plurality of microplate reaction plates 7 arranged on the carrier plate 5. The carrier plate 5 is used to place the microplate reaction plates 7, and the microplate reaction plates 7 carry reaction samples. The microplate reaction plates 7 include a flat microplate reaction plate 71 and a V-shaped microplate reaction plate 72, which are selected according to different reaction samples. The flat microplate reaction plate 71 is provided with flat microholes 701, and the V-shaped microplate reaction plate 72 is provided with V-shaped microholes 702.

[0034] A control mechanism 11 is arranged on one side of the imaging mechanism for controlling the movement of each driving member.

[0035] A light source is arranged below the carrier mechanism to facilitate the camera assembly 9 to collect image data.

[0036] When the carrier plate 5 is placed into the device, a drawer-type connection method is adopted, and a carrier plate handle 8 is arranged at one end close to the outside of the device to facilitate the insertion and removal of the carrier plate 5.

[0037] The outer periphery of the device is covered with a housing 12 to facilitate the use of the device and ensure the safety of the device during use.

[0038] An ultraviolet lamp 10 is arranged on one side of the imaging mechanism. The height of the ultraviolet lamp 10 is higher than that of the imaging mechanism to disinfect the device for convenient subsequent use.

[0039] One of the methods of using this device is as follows:

[0040] 1. According to different experiments, select the corresponding microplate reaction plate for the experiment and place the microplate reaction plate after the experiment in the carrier plate.

[0041] 2. Place the carrier plate carrying the microplate reaction plate into the device for image data collection.

[0042] 3. According to the characteristics of the experiment, select the camera for data collection and transmit the collected data to an external recognition device.

[0043] 4. After use, use the ultraviolet lamp for disinfection for convenient next use.

[0044] The above are only the preferred embodiments of the present utility model, and do not impose any form of limitation on the present utility model. Although the present utility model has been disclosed above with the preferred embodiments, it is not intended to limit the present utility model. Any person skilled in the art can make some changes or modifications to equivalent embodiments by using the disclosed technical content within the scope of the technical solution of the present utility model. However, as long as it does not depart from the content of the technical solution of the present utility model, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present utility model still fall within the scope of the technical solution of the present utility model.

Claims

1. An imaging device for immunoassay detection, comprising a base plate (1), an imaging mechanism, a control mechanism (11) and a carrying mechanism, wherein the imaging mechanism and the control mechanism (11) are mounted on the base plate (1), and the carrying mechanism is detachably arranged on the base plate (1); characterized in that: The imaging mechanism is provided with a camera assembly (9), and the camera assembly (9) is provided with a first camera (91) and a second camera (92) that can be used alternately; the carrying mechanism is provided with a microporous reaction plate (7), and the microporous reaction plate (7) carries a reaction sample. The microporous reaction plate (7) comprises a flat microporous reaction plate (71) and a V-shaped microporous reaction plate (72), which are selected according to different reaction samples. The flat microporous reaction plate (71) is provided with a flat microporous (701), and the V-shaped microporous reaction plate (72) is provided with a V-shaped microporous.

2. The imaging device for immunoassay detection according to claim 1, characterized in that: The imaging mechanism further comprises a plurality of driving members and drag chains matched thereto, and a camera assembly (9) arranged on one side of the driving member, wherein the driving mechanism comprises a first driving member (13) for driving the camera assembly (9) to move horizontally, a first drag chain (2) matched with the first driving member (13) being connected thereto and protecting cables connected to the first driving member (13), and a second driving member (14) for driving the camera assembly (9) to move vertically, a second drag chain (3) matched with the second driving member (14) being connected thereto, and a moving track of the second driving member (14) being a first slide rail (4). ) and a second slide rail (6), the second driving member (14) being track-connected to the first slide rail (4) and the second slide rail (6); the camera assembly (9) being connected to one side of the first driving member (13), being flipped by a rotating mechanism disposed at the connection between the first driving member (13) and the camera assembly (9), and being replaced by the rotating mechanism so as to facilitate the alternating use of the first camera (91) and the second camera (92); the camera assembly (9) being height-adjustable by a lifting mechanism disposed at the connection between the first driving member (13) and the camera assembly (9).

3. The imaging device for immunoassay detection according to claim 1, characterized in that: The control mechanism is arranged at one side of the imaging mechanism to control the movement of each driving member.

4. The imaging device for immunoassay detection according to claim 1, characterized in that: The carrying mechanism is arranged below the imaging mechanism, and image data of the carrying mechanism is collected by moving the camera assembly (9). The carrying mechanism is provided with a carrying plate (5) for carrying the microporous reaction plate (7).

5. The imaging device for immunoassay detection according to claim 1, characterized in that: A light source is arranged below the carrying mechanism.

6. The imaging device for immunoassay detection according to claim 4, characterized in that: When the carrying tray (5) is placed in the device, a drawer-type connection method is adopted, and a carrying tray handle (8) is provided at one end close to the outside of the device.

7. The imaging device for immunoassay detection according to claim 1, characterized in that: The outer periphery of the device is covered by a shell (12).

8. The imaging device for immunoassay detection according to claim 1, characterized in that: An ultraviolet lamp (10) is arranged on one side of the imaging mechanism, and the height of the ultraviolet lamp (10) is higher than the imaging mechanism.

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