Biological sample low-temperature storage refrigerator

By using lifting shovel mechanism and Stirling refrigeration mechanism in biological sample cryogenic storage refrigerators, the safety and cost problems of sample boxes are solved in ultra-low temperature environments, and efficient and safe sample management and low-cost liquid nitrogen use are achieved.

CN222993283UActive Publication Date: 2025-06-17SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIP CO LTD
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Patent Information

Application Number
CN202421800516.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-29
Publication Date
2025-06-17
Estimated Expiration
2034-07-29

AI Technical Summary

Technical Problem

Existing biological sample low-temperature storage devices are prone to damage when working the robotic arm in ultra-low temperature environments, which affects the accuracy of accurate sample picking. They also consume large liquid nitrogen, have high cost, and have low safety of the shovel mechanism, which is prone to the risk of sample box falling off.

Method used

A biological sample cryogenic storage refrigerator is designed, and the sample box is fetched and transported in the sample storage compartment using a lifting shovel mechanism, and the clamping and safe transport of the sample box is achieved through the angle adjustment component and the grabbing component. At the same time, the Stirling refrigeration mechanism is used for refrigeration, which realizes the recycling of liquid nitrogen, reduces the cost of liquid nitrogen, and has the function of automatic temperature regulation.

Benefits of technology

It improves the efficiency and safety of sample box picking and transporting, reduces the risk of sample box falling off during transport, saves the use of liquid nitrogen, reduces the cost of liquid nitrogen, and realizes automatic temperature adjustment, improving the safety and economicality of the equipment.

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Abstract

The utility model discloses a biological sample low-temperature storage refrigerator which comprises a sample storage cabin, an operation area and a refrigeration mechanism. An operation area is arranged on the side edge of the sample storage cabin, a refrigeration mechanism is arranged on the sample storage cabin, and the refrigeration mechanism can refrigerate the interior of the sample storage cabin; the operation area can be used for storing and taking samples in the sample storage cabin, transferring and picking the samples, and the sample storage cabin can be used for storing the samples in the basket; a lifting shovel plate mechanism is arranged in the operation area and can grab and transfer sample boxes. The sample box transferring device has the advantages that the lifting shovel plate mechanism penetrates through the rotating door assembly to shovel and transfer sample boxes in the sample storage bin, the lifting shovel plate mechanism can shovel samples and clamp the samples, it can be guaranteed that the sample boxes cannot fall off, Stirling refrigeration is adopted through the refrigeration mechanism, and the sample box transferring efficiency is improved. The use amount of liquid nitrogen can be reduced, the cost of using the liquid nitrogen for a long time is reduced, the liquid nitrogen can be used for a long time after being supplemented once, and automatic temperature adjustment can be achieved.
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Description

Technical Field

[0001] The utility model relates to the technical field of sample storage, in particular to a cryogenic storage refrigerator for biological samples. Background Art

[0002] In the field of biological sample storage, cryogenic access devices are used to cryogenically store biological samples such as blood samples, vaccines, and bacterial and viral seeds, so that the samples can be actively preserved at a low temperature.

[0003] The publication number is CN116409573A, and the application date is February 27, 2023. A fully automatic sample cryogenic access system has two sets of rotating cylinders for storage racks inside its housing, thus improving its storage capacity. At the same time, the rotating cylinder is a single-layer rotating cylinder, which greatly simplifies the complexity of the lifting shovel mechanism for accessing the storage racks. However, two storage devices are arranged inside the sample storage housing and are both in an ultra-low temperature environment. The manipulator arranged in the middle is prone to damage during long-term operation, affecting the accuracy of accurately picking the storage rack, thus having a very serious impact on sample safety. Moreover, the current use of liquid nitrogen consumes too much, and the liquid nitrogen cost is relatively high. And the current shovel mechanism has low safety, and there is a risk of falling off during the process of shoveling and transporting the sample box. Therefore, the inventor designed a cryogenic storage refrigerator for biological samples with a large storage capacity and a safe shoveling process. Summary of the Utility Model

[0004] The purpose of this part is to outline some aspects of the embodiments of the utility model and briefly introduce some preferred embodiments. Simplifications or omissions may be made in this part, as well as in the abstract and the title of the specification of this application, to avoid obscuring the purpose of this part, the abstract of the specification, and the title of the utility model. However, such simplifications or omissions shall not be used to limit the scope of the utility model.

[0005] In view of the problems existing in the above or prior art, the present utility model is proposed.

[0006] Therefore, the purpose of the present utility model is to provide a cryogenic storage refrigerator for biological samples, which can shovel the samples in the sample storage compartment through a shovel mechanism, and can ensure clamping operation on the sample box during the shoveling and transportation process, and can store the sample box after shoveling to a specific position, improving the shoveling efficiency and safety, reducing the risk of the sample box falling during the shoveling process. Refrigeration can be achieved by compression refrigeration or Stirling refrigeration. By using Stirling refrigeration, the liquid nitrogen can be circulated for vaporization and liquefaction, thereby saving liquid nitrogen, significantly reducing the liquid nitrogen cost, and realizing the function of automatic temperature adjustment.

[0007] To solve the above technical problems, the present utility model provides the following technical solution: A cryogenic storage refrigerator for biological samples, which includes a sample storage chamber, an operation area, and a refrigeration mechanism; an operation area is provided on the side of the sample storage chamber, and a refrigeration mechanism is provided on the sample storage chamber, and the refrigeration mechanism can refrigerate the inside of the sample storage chamber; the operation area can access, transfer, and pick up the samples in the sample storage chamber, and the sample storage chamber can store the basket samples; a lifting shovel plate mechanism is provided in the operation area, and the lifting shovel plate mechanism can grab and transfer the sample box.

[0008] As a preferred solution of the cryogenic storage refrigerator for biological samples of the present utility model, wherein: the lifting shovel plate mechanism includes an angle adjustment component and a grasping component; the angle adjustment component can perform at least one-level rotation, and a grasping component is provided on the angle adjustment component, and the angle adjustment component can drive the grasping component to turn, and the grasping component can shovel and store the sample box inside the sample storage chamber.

[0009] As a preferred solution of the cryogenic storage refrigerator for biological samples of the present utility model, wherein: the grasping component includes a support telescopic member and a grasping member; the support telescopic member can drive the grasping member to move horizontally, and the sample box can be shoveled through the grasping member.

[0010] As a preferred solution of the cryogenic storage refrigerator for biological samples of the present utility model, wherein: the grasping component further includes a guiding and limiting frame member, the guiding and limiting frame member is connected to the support telescopic member, and the guiding and limiting frame member can clamp the grasping member.

[0011] As a preferred solution of the cryogenic storage refrigerator for biological samples of the present utility model, wherein: the support telescopic member includes a support plate, a first driving member, and a first driven member; one end of the support plate is connected to the angle adjustment component, a first driving member is provided on the support plate, a first driven member is provided on the side of the first driving member, the front end of the first driven member is connected to the grasping member, the first driving member can drive the first driven member to move horizontally along the support plate, and the first driven member can drive the grasping member to move horizontally.

[0012] As a preferred solution of the cryogenic storage refrigerator for biological samples of the present utility model, wherein: the grasping member includes a support claw, an elastic telescopic member, and a guiding end; elastic telescopic members are respectively provided on both sides of the front end of the first driven member, a support claw is provided on the side of the elastic telescopic member, and a guiding end is provided on the outer side of the support claw, and the guiding end can guide the support claw to enter the guiding and limiting frame member.

[0013] As a preferred solution of the cryogenic storage refrigerator for biological samples of the present utility model, wherein: the two groups of support claws can move away from or towards each other, and the support claws can clamp or loosen the plate rack.

[0014] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: The first driven member can pass through the guiding and limiting frame member and be connected to the grasping member.

[0015] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: The angle adjustment assembly includes a first-level rotating member, a second-level rotating member, and a third-level rotating member; the two sides of the second-level rotating member are respectively connected to the first-level rotating member and the third-level rotating member, one end of the third-level rotating member is connected to the grasping assembly, and the first-level rotating member, the second-level rotating member, and the third-level rotating member can all rotate by an angle.

[0016] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: It further includes a vertical driving mechanism, on which an angle adjustment assembly is arranged, and the vertical driving mechanism can drive the angle adjustment assembly and the grasping assembly to move up and down.

[0017] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: The refrigeration mechanism is a compressor refrigeration mechanism or a Stirling refrigeration mechanism. The Stirling refrigeration mechanism is arranged at the upper end of the sample storage chamber, and the compressor refrigeration mechanism is arranged at the side end of the sample storage chamber.

[0018] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: A ventilation mechanism is arranged inside the compressor refrigeration mechanism, and the ventilation mechanism can ventilate the compressor refrigeration mechanism. A maintenance port is also arranged on the compressor refrigeration mechanism, and the compressor refrigeration mechanism can be maintained through the maintenance port.

[0019] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: The ventilation mechanism includes an exhaust member and a pipeline; the exhaust member is arranged inside the pipeline, one end of the pipeline is communicated with the compressor refrigeration mechanism, and the other end passes through the operation area and leads to the outside of the operation area.

[0020] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: The Stirling refrigeration mechanism includes a Stirling refrigeration module, a cold head, and a storage chamber; the lower end of the Stirling refrigeration module is connected to the cold head, the storage chamber is detachably connected to the Stirling refrigeration module, and the cold head is arranged inside the storage chamber. Liquid nitrogen can be stored in the storage chamber, and the cold head can liquefy the vaporized nitrogen.

[0021] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: A rotating door assembly is further arranged on the sample storage chamber, and the rotating door assembly is arranged inside the operation area, and the rotating door assembly can open and close the shoveling channel.

[0022] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: The rotary door assembly includes a rotary door driving member and a rotary door; the lower end of the rotary door driving member is connected to the rotary door, and the rotary door driving member can drive the rotary door to open and close the shoveling channel.

[0023] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: A rotatable rotating storage rack assembly is arranged in the sample storage compartment, and the rotating storage rack assembly can store and retrieve sample boxes.

[0024] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: A transfer port is arranged on the side of the operation area, a transfer door is arranged in the transfer port, and the transfer door can open and close the transfer port.

[0025] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: A code scanning mechanism is arranged on the side of the transfer door, and the code scanning mechanism can scan the sample box.

[0026] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: A storage compartment maintenance opening is provided on the sample storage compartment, a maintenance door is arranged in the storage compartment maintenance opening, the maintenance door can open and close the storage compartment maintenance opening, and when the maintenance door is opened, the inside of the sample storage compartment can be maintained.

[0027] As a preferred embodiment of the cryogenic storage refrigerator for biological samples of the present utility model, the following is provided: A display control device is further arranged on the sample storage compartment, and the display control device can display the internal parameters of the sample storage compartment and adjust and control the work.

[0028] Advantages of the present utility model: The present utility model can shovel and transfer the sample box in the sample storage compartment through the lifting shovel plate mechanism passing through the rotary door assembly, which can improve the efficiency of shoveling the sample box. The lifting shovel plate mechanism can realize shoveling the sample and clamping the sample, which can ensure that the sample box will not fall off during the transfer process. Through the refrigeration mechanism, Stirling refrigeration can be adopted, which can reduce the usage amount of liquid nitrogen, reduce the cost of long-term use of liquid nitrogen, and can be used for a long time after replenishing liquid nitrogen once. It can realize automatic temperature adjustment, which is not only energy-saving and environmentally friendly but also convenient for disassembly, replacement, and cleaning. Description of the Drawings

[0029] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings. Among them:

[0030] Figure 1 It is the overall schematic diagram of Embodiment 1 of the cryogenic storage refrigerator for biological samples.

[0031] Figure 2 Schematic diagram of another perspective of Embodiment 1 of the cryogenic storage refrigerator for biological samples.

[0032] Figure 3 Compression refrigeration mechanism in Embodiment 1 of the cryogenic storage refrigerator for biological samples.

[0033] Figure 4 Internal schematic diagram of Embodiment 1 of the cryogenic storage refrigerator for biological samples.

[0034] Figure 5 Stereoscopic schematic diagram of the lifting shovel plate mechanism of the cryogenic storage refrigerator for biological samples.

[0035] Figure 6 Schematic diagram of the rotating storage rack assembly of the cryogenic storage refrigerator for biological samples.

[0036] Figure 7 Enlarged schematic diagram of the lifting shovel plate mechanism of the cryogenic storage refrigerator for biological samples.

[0037] Figure 8 Exploded schematic diagram of the lifting shovel plate mechanism of the cryogenic storage refrigerator for biological samples.

[0038] Figure 9 Schematic diagram of the rotating door assembly of the cryogenic storage refrigerator for biological samples.

[0039] Figure 10 Overall schematic diagram of Embodiment 2 of the cryogenic storage refrigerator for biological samples.

[0040] Figure 11 Schematic diagram of the operation area of Embodiment 2 of the cryogenic storage refrigerator for biological samples.

[0041] Figure 12 Schematic diagram of another perspective of Embodiment 2 of the cryogenic storage refrigerator for biological samples.

[0042] Figure 13 Internal schematic diagram of Embodiment 2 of the cryogenic storage refrigerator for biological samples.

[0043] Figure 14 Cross-sectional view of the sample storage compartment in Embodiment 2 of the cryogenic storage refrigerator for biological samples.

[0044] Reference numerals: sample storage chamber, 1; operation area, 2; refrigeration mechanism, 3; lifting shovel plate mechanism, 21; support telescopic member, 2121; grasping member, 2122; guiding and limiting frame member, 2123; support plate, 21211; first driving member, 21212; first driven member, 21213; support jaw, 21221; elastic telescopic member, 21222; guiding end, 21223; vertical driving mechanism, 213; compression refrigeration mechanism, 31; Stirling refrigeration mechanism, 32; ventilation mechanism, 33; exhaust member, 331; pipeline, 332; Stirling refrigeration module, 321; cold head, 322; storage cavity, 323; rotary door assembly, 4; rotary door driving member, 41; rotary door, 42; rotating storage rack assembly, 11; transfer door, 29; code scanning mechanism, 5; maintenance door, 7; display control device, 8; Detailed implementation manners

[0045] To make the above objects, features and advantages of the present utility model more obvious and understandable, the following detailed description of the specific implementation manners of the present utility model will be given in conjunction with the accompanying drawings of the specification.

[0046] In the following description, many specific details are set forth to facilitate a thorough understanding of the present utility model. However, the present utility model may also be implemented in other ways different from those described herein. Those skilled in the art can make similar generalizations without departing from the connotation of the present utility model. Therefore, the present utility model is not limited by the specific embodiments disclosed below.

[0047] Secondly, the so-called "one embodiment" or "embodiment" herein refers to a specific feature, structure or characteristic that may be included in at least one implementation manner of the present utility model. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that excludes other embodiments.

[0048] Embodiment 1

[0049] Referring to Figures 1 to 9 , this is the first embodiment of the present utility model. This embodiment provides a low-temperature storage refrigerator for biological samples, which includes a sample storage chamber 1, an operation area 2, and a refrigeration mechanism 3; a refrigeration mechanism 3 is provided on the sample storage chamber 1, and the samples in the sample storage chamber 1 can be cryogenically frozen through the refrigeration mechanism 3. An operation area 2 is provided on the side of the sample storage chamber 1, and the sample boxes in the sample storage chamber 1 can be shoveled, transported, and pipette-tubed through the operation area 2.

[0050] Specifically, there is a sample storage compartment 1, an operation area 2, and a refrigeration mechanism 3; an operation area 2 is provided on the side of the sample storage compartment 1, a refrigeration mechanism 3 is provided on the sample storage compartment 1, and the refrigeration mechanism 3 can refrigerate the inside of the sample storage compartment 1; the operation area 2 can access, transfer, and pick up the samples in the sample storage compartment 1, and the sample storage compartment 1 can store the basket samples;

[0051] An elevating shovel plate mechanism 21 is provided in the operation area 2, and the elevating shovel plate mechanism 21 can grab and transfer the sample box.

[0052] Preferably, the elevating shovel plate mechanism 21 can be lifted and the horizontal angle can also be adjusted.

[0053] Furthermore, the elevating shovel plate mechanism 21 includes an angle adjustment component and a grasping component; the angle adjustment component can perform at least one - level rotation, the grasping component is provided on the angle adjustment component, the angle adjustment component can drive the grasping component to turn, and the grasping component can shovel and store the sample box inside the sample storage compartment 1.

[0054] Preferably, the angle adjustment component can drive the grasping component to change the angle; the grasping component can shovel the sample box and can also clamp the sample box to prevent the sample box from falling off during the transfer process.

[0055] Furthermore, the grasping component includes a support telescopic member 2121 and a grasping member 2122; the support telescopic member 2121 can drive the grasping member 2122 to move horizontally, and the sample box can be shoveled by the grasping member 2122.

[0056] Furthermore, the grasping component further includes a guiding and limiting frame member 2123, the guiding and limiting frame member 2123 is connected to the support telescopic member 2121, and the guiding and limiting frame member 2123 can clamp the grasping member 2122.

[0057] Preferably, the support telescopic member 2121 can drive the grasping member 2122 to move horizontally, the sample box grabbed by the grasping member 2122 can enter the guiding and limiting frame member 2123 through the support telescopic member 2121, and the guiding and limiting frame member 2123 can squeeze and limit the grasping member 2122, so that the grasping member 2122 clamps the sample box.

[0058] Further, the support telescopic member 2121 includes a support plate 21211, a first driving member 21212, and a first driven member 21213. One end of the support plate 21211 is connected to the angle adjustment assembly. The first driving member 21212 is arranged on the support plate 21211, and the first driven member 21213 is arranged on the side of the first driving member 21212. The front end of the first driven member 21213 is connected to the grasping member 2122. The first driving member 21212 can drive the first driven member 21213 to move horizontally along the support plate 21211, and the first driven member 21213 can drive the grasping member 2122 to move horizontally.

[0059] Preferably, the first driving member 21212 includes a motor and a gear, and the first driven member 21213 is a straight tooth plate. The gear can drive the straight tooth plate to move back and forth, and the straight tooth plate moves horizontally along the support plate 21211. The support plate 21211 can support and guide the straight tooth plate.

[0060] Further, the grasping member 2122 includes a support claw 21221, an elastic telescopic member 21222, and a guiding end 21223. Elastic telescopic members 21222 are respectively arranged on both sides of the front end of the first driven member 21213. Support claws 21221 are arranged on the sides of the elastic telescopic members 21222. A guiding end 21223 is arranged on the outer side of the support claw 21221. The guiding end 21223 can guide the support claw 21221 to enter the guiding and limiting frame member 2123.

[0061] Preferably, the support claw 21221 can scoop up the sample box and support the sample box. After the support claw 21221 grabs the sample box, the first driving member 21212 drives the first driven member 21213 to drive the grasping member 2122 into the guiding and limiting frame member 2123. The guiding end 21223 first contacts the guiding and limiting frame member 2123, and then the guiding and limiting frame member 2123 squeezes the support claw 21221, so that the support claw 21221 squeezes the elastic telescopic member 21222, causing the two groups of support claws 21221 to move towards the middle, thereby clamping the sample box by the support claws 21221.

[0062] Preferably, after reaching the transfer position and when the sample box needs to be placed at a specified position, the first driving member 21212 drives the first driven member 21213 to drive the grasping member 2122 to disengage from the guiding and limiting frame member 2123. Under the action of the elastic telescopic member 21222, the two groups of support claws 21221 move away from each other. At this time, the two groups of support claws 21221 cancel the limitation on the sample box, and it can be placed at a specific position.

[0063] Preferably, the elastic telescopic member 21222 can adopt a pin shaft and a spring, with a spring arranged on the pin shaft. Of course, an elastic device in the prior art can also be used, as long as it can make the support jaws 21221 move away from or towards each other.

[0064] Further, the two groups of support jaws 21221 can move away from or towards each other, and the support jaws 21221 can clamp or loosen the plate rack.

[0065] Further, the first driven member 21213 can pass through the guiding and limiting frame member 2123 and be connected to the grasping member 2122.

[0066] Further, the angle adjustment assembly includes a first-level rotating member, a second-level rotating member, and a third-level rotating member; the two sides of the second-level rotating member are respectively connected to the first-level rotating member and the third-level rotating member, one end of the third-level rotating member is connected to the grasping assembly, and the first-level rotating member, the second-level rotating member, and the third-level rotating member can all rotate angles.

[0067] Preferably, the first-level rotating member can rotate on the vertical driving mechanism 213, the second-level rotating member can rotate around the first-level rotating member, and the third-level rotating member can rotate around the second-level rotating member, so as to achieve more conversion angles and a wider adaptation range.

[0068] Further, it further includes a vertical driving mechanism 213. An angle adjustment assembly is arranged on the vertical driving mechanism 213, and the vertical driving mechanism 213 can drive the angle adjustment assembly and the grasping assembly to lift.

[0069] Preferably, by setting the vertical driving mechanism 213, the sample boxes on each layer in the vertical direction of the rotating storage rack assembly 11 can be shoveled.

[0070] Further, the refrigeration mechanism 3 is a compressor refrigeration mechanism 31; the compressor refrigeration mechanism 31 is arranged at the side end of the sample storage chamber 1.

[0071] Preferably, the samples in the sample storage chamber 1 can be frozen by compressor refrigeration.

[0072] Further, a ventilation mechanism 33 is arranged in the compressor refrigeration mechanism 31. The ventilation mechanism 33 can ventilate the compressor refrigeration mechanism 31, and a maintenance port is also arranged on the compressor refrigeration mechanism 31. The compressor refrigeration mechanism 31 can be maintained through the maintenance port.

[0073] Preferably, the heat generated by the compressor refrigeration mechanism 31 can be conveyed out through the ventilation mechanism 33; the compressor refrigeration mechanism 31 can be conveniently maintained through the maintenance port.

[0074] Further, the ventilation mechanism 33 includes an exhaust member 331 and a duct 332; the exhaust member 331 is disposed within the duct 332, one end of the duct 332 is communicated with the compressor refrigeration mechanism 31, and the other end passes through the operation area 2 and leads to the outside of the operation area 2.

[0075] Further, a rotating door assembly 4 is also provided on the sample storage chamber 1, and the rotating door assembly 4 is disposed inside the operation area 2, and the rotating door assembly 4 can open and close the shoveling channel.

[0076] Preferably, when the rotating door assembly 4 can open the shoveling channel, the lifting shovel plate mechanism 21 can shovel the sample box in the sample storage chamber 1 through the shoveling channel. When the rotating door assembly 4 closes the shoveling channel, the sample storage chamber 1 and the operation area 2 are isolated, and the lifting shovel plate mechanism 21 cannot shovel the sample box in the sample storage chamber 1.

[0077] Further, the rotating door assembly 4 includes a rotating door driving member 41 and a rotating door 42; the lower end of the rotating door driving member 41 is connected to the rotating door 42, and the rotating door driving member 41 can drive the rotating door 42 to open and close the shoveling channel.

[0078] Further, a rotatable rotating storage rack assembly 11 is disposed in the sample storage chamber 1, and the rotating storage rack assembly 11 can store and retrieve the sample boxes.

[0079] Preferably, by providing the rotatable rotating storage rack assembly 11, it can cooperate with the lifting shovel plate mechanism 21, so that the sample boxes on each vertical column and each horizontal row of the rotating storage rack assembly 11 can be shoveled.

[0080] Further, a transfer port is provided on the side of the operation area 2, and a transfer door 29 is disposed in the transfer port, and the transfer door 29 can open and close the transfer port.

[0081] Preferably, after the transfer door 29 is opened, the sample box can be transferred from the outside through the transfer port into the operation area 2 for tube picking work or sample storage work.

[0082] Further, a code scanning mechanism 5 is provided on the side of the transfer door 29, and the code scanning mechanism 5 can scan the sample box.

[0083] Further, a storage chamber inspection opening is provided on the sample storage chamber 1, and an inspection door 7 is disposed in the storage chamber inspection opening. The inspection door 7 can open and close the storage chamber inspection opening, and when the inspection door 7 is opened, the inside of the sample storage chamber 1 can be inspected.

[0084] Preferably, by providing the inspection door 7, when a failure occurs inside the sample storage chamber 1, the inspection door 7 can be quickly opened for maintenance, and the quickly rotating storage rack assembly 11 can be repaired.

[0085] Furthermore, a display control device 8 is also provided on the sample storage compartment 1. The display control device 8 can display the internal parameters of the sample storage compartment 1 and adjust and control the operation.

[0086] Preferably, by setting the display control device 8, commands can be issued to make the equipment operate, and the progress of each equipment can be displayed in real time. For example, the internal temperature can be displayed, or the position of the sample box on the rotating storage rack assembly 11 can be displayed, etc.

[0087] In summary, in the present utility model, the lifting shovel plate mechanism 21 can pass through the rotating door assembly 4 to scoop and transfer the sample box in the sample storage compartment 1, which can improve the efficiency of scooping the sample box. The lifting shovel plate mechanism 21 can scoop the sample and clamp the sample, which can ensure that the sample box will not fall off during the transfer process; by setting the maintenance door 7, the rotating storage rack assembly 11 inside the sample storage compartment 1 can be quickly repaired, etc.

[0088] Embodiment 2

[0089] Referring to Figures 5 to 14 , this is the second embodiment of the present utility model. In the previous embodiment, the biological sample low-temperature storage refrigerator includes a sample storage compartment 1, an operation area 2, and a refrigeration mechanism 3; a refrigeration mechanism 3 is provided on the sample storage compartment 1, and the sample in the sample storage compartment 1 can be cryogenically frozen through the refrigeration mechanism 3. An operation area 2 is provided on the side of the sample storage compartment 1, and the sample box in the sample storage compartment 1 can be scooped, transferred, and pipetted through the operation area 2.

[0090] Specifically, there is a sample storage compartment 1, an operation area 2, and a refrigeration mechanism 3; an operation area 2 is provided on the side of the sample storage compartment 1, a refrigeration mechanism 3 is provided on the sample storage compartment 1, and the refrigeration mechanism 3 can refrigerate the inside of the sample storage compartment 1; the operation area 2 can access, transfer, and pipette the samples in the sample storage compartment 1, and the sample storage compartment 1 can store the basket samples;

[0091] A lifting shovel plate mechanism 21 is provided in the operation area 2, and the lifting shovel plate mechanism 21 can grab and transfer the sample box.

[0092] Preferably, the lifting shovel plate mechanism 21 can be lifted and the horizontal angle can also be adjusted.

[0093] Furthermore, the lifting shovel plate mechanism 21 includes an angle adjustment component and a grabbing component; the angle adjustment component can perform at least one-level rotation, a grabbing component is provided on the angle adjustment component, the angle adjustment component can drive the grabbing component to turn, and the grabbing component can scoop and store the sample box inside the sample storage compartment 1.

[0094] Preferably, the angle adjustment component can drive the grasping component to rotate; the grasping component can scoop up the sample box and clamp the sample box to prevent the sample box from falling off during transportation.

[0095] Furthermore, the grasping component includes a support telescopic member 2121 and a grasping member 2122; the support telescopic member 2121 can drive the grasping member 2122 to move horizontally, and the grasping member 2122 can scoop up the sample box.

[0096] Furthermore, the grasping component further includes a guiding and limiting frame member 2123, which is connected to the support telescopic member 2121 and can clamp the grasping member 2122.

[0097] Preferably, the support telescopic member 2121 can drive the grasping member 2122 to move horizontally. The sample box grasped by the grasping member 2122 can enter the guiding and limiting frame member 2123 through the support telescopic member 2121, and the guiding and limiting frame member 2123 can squeeze and limit the grasping member 2122, so that the grasping member 2122 clamps the sample box.

[0098] Furthermore, the support telescopic member 2121 includes a support plate 21211, a first driving member 21212, and a first driven member 21213; one end of the support plate 21211 is connected to the angle adjustment component. The first driving member 21212 is arranged on the support plate 21211, the first driven member 21213 is arranged on the side of the first driving member 21212, and the front end of the first driven member 21213 is connected to the grasping member 2122. The first driving member 21212 can drive the first driven member 21213 to move horizontally along the support plate 21211, and the first driven member 21213 can drive the grasping member 2122 to move horizontally.

[0099] Preferably, the first driving member 21212 includes a motor and a gear, the first driven member 21213 is a straight tooth plate, the gear can drive the straight tooth plate to move back and forth, and the straight tooth plate moves horizontally along the support plate 21211. The support plate 21211 can support and guide the straight tooth plate.

[0100] Furthermore, the grasping member 2122 includes a support jaw 21221, an elastic telescopic member 21222, and a guiding end 21223; elastic telescopic members 21222 are respectively arranged on both sides of the front end of the first driven member 21213, a support jaw 21221 is arranged on the side of the elastic telescopic member 21222, and a guiding end 21223 is arranged on the outer side of the support jaw 21221. The guiding end 21223 can guide the support jaw 21221 to enter the guiding and limiting frame member 2123.

[0101] Preferably, the supporting gripper 21221 can scoop up and support the sample box. After the supporting gripper 21221 grabs the sample box, the first driving member 21212 drives the first driven member 21213 to drive the grasping member 2122 into the guiding and limiting frame member 2123. The guiding end 21223 first contacts the guiding and limiting frame member 2123, and then the guiding and limiting frame member 2123 squeezes the supporting gripper 21221, so that the supporting gripper 21221 squeezes the elastic telescopic member 21222, causing the two groups of supporting grippers 21221 to move towards the middle, thereby clamping the sample box by the supporting gripper 21221.

[0102] Preferably, after reaching the transfer position, when the sample box needs to be placed at a specified position, the first driving member 21212 drives the first driven member 21213 to drive the grasping member 2122 to disengage from the guiding and limiting frame member 2123. Under the action of the elastic telescopic member 21222, the two groups of supporting grippers 21221 move away from each other. At this time, the two groups of supporting grippers 21221 cancel the limit on the sample box, and it can be placed at a specific position.

[0103] Preferably, the elastic telescopic member 21222 can adopt a pin shaft and a spring, with a spring arranged on the pin shaft. Of course, an elastic device of the prior art can also be used, as long as it can make the supporting gripper 21221 move away from or towards each other.

[0104] Furthermore, the two groups of supporting grippers 21221 can move away from or towards each other, and the supporting gripper 21221 can clamp or release the plate rack.

[0105] Furthermore, the first driven member 21213 can pass through the guiding and limiting frame member 2123 and be connected to the grasping member 2122.

[0106] Furthermore, the angle adjustment assembly includes a first-level rotating member, a second-level rotating member, and a third-level rotating member; the two sides of the second-level rotating member are respectively connected to the first-level rotating member and the third-level rotating member, and one end of the third-level rotating member is connected to the grasping assembly. The first-level rotating member, the second-level rotating member, and the third-level rotating member can all rotate angles.

[0107] Preferably, the first-level rotating member can rotate on the vertical driving mechanism 213, the second-level rotating member can rotate around the first-level rotating member, and the third-level rotating member can rotate around the second-level rotating member, so as to achieve more conversion angles and a wider adaptation range.

[0108] Furthermore, it further includes a vertical driving mechanism 213. The vertical driving mechanism 213 is provided with an angle adjustment assembly, and the vertical driving mechanism 213 can drive the angle adjustment assembly and the grasping assembly to lift.

[0109] Preferably, by setting the vertical driving mechanism 213, the sample boxes on each layer in the vertical direction of the rotating storage rack assembly 11 can be shoveled.

[0110] Further, the refrigeration mechanism 3 is a Stirling refrigeration mechanism 32, and the Stirling refrigeration mechanism 32 is arranged at the upper end of the sample storage chamber 1.

[0111] Preferably, by the Stirling refrigeration mechanism 32, a large amount of liquid nitrogen can be saved, the liquid nitrogen can be recycled, and the use cost is reduced.

[0112] Further, the Stirling refrigeration mechanism 32 includes a Stirling refrigeration module 321, a cold head 322, and a storage cavity 323; the lower end of the Stirling refrigeration module 321 is connected to the cold head 322, the storage cavity 323 is detachably connected to the Stirling refrigeration module 321, and the cold head 322 is arranged inside the storage cavity 323. Liquid nitrogen can be stored in the storage cavity 323, and the cold head 322 can liquefy the vaporized nitrogen.

[0113] Preferably, the storage cavity 323 can be circular, cylindrical or other irregular shapes; and different types of storage cavities 323 can be docked with the Stirling refrigeration module 321 and the cold head 322. The storage cavity 323 is detachably connected to the Stirling refrigeration module 321, which is convenient for replacing different types of storage cavities 323.

[0114] Preferably, only a certain amount of liquid nitrogen needs to be initially placed in the storage cavity 323. The liquid nitrogen will vaporize into nitrogen in the storage cavity 323, and the nitrogen will rise into the cold head 322. After being cooled by the Stirling refrigeration module 321 and the cold head 322, the nitrogen can be converted into liquid nitrogen and flow back into the storage cavity 323 again, and then the operations of vaporization and liquefaction can be carried out to achieve a cycle, and the liquid nitrogen has zero loss, greatly saving the use of liquid nitrogen and reducing the liquid nitrogen cost.

[0115] Further, a rotating door assembly 4 is also arranged on the sample storage chamber 1, and the rotating door assembly 4 is arranged inside the operation area 2. The rotating door assembly 4 can open and close the shoveling channel.

[0116] Preferably, when the rotating door assembly 4 opens the shoveling channel, the lifting shovel plate mechanism 21 can shovel the sample boxes in the sample storage chamber 1 through the shoveling channel. When the rotating door assembly 4 closes the shoveling channel, the sample storage chamber 1 and the operation area 2 are isolated, and the lifting shovel plate mechanism 21 cannot shovel the sample boxes in the sample storage chamber 1.

[0117] Further, the rotating door assembly 4 includes a rotating door driving member 41 and a rotating door 42; the lower end of the rotating door driving member 41 is connected to the rotating door 42, and the rotating door driving member 41 can drive the rotating door 42 to open and close the shoveling channel.

[0118] Furthermore, a rotatable rotating storage rack assembly 11 is provided inside the sample storage compartment 1, and the rotating storage rack assembly 11 can access and store sample boxes.

[0119] Preferably, by providing the rotatable rotating storage rack assembly 11, it can cooperate with the lifting shovel plate mechanism 21, so that each vertical column and each horizontal row of sample boxes on the rotating storage rack assembly 11 can be shoveled.

[0120] Furthermore, a transfer port is provided on the side of the operation area 2, and a transfer door 29 is provided inside the transfer port. The transfer door 29 can open and close the transfer port.

[0121] Preferably, after the transfer door 29 is opened, the sample box can be transferred from the outside through the transfer port into the operation area 2 for pipette picking work or sample storage work.

[0122] Furthermore, a code scanning mechanism 5 is provided on the side of the transfer door 29, and the code scanning mechanism 5 can scan the sample box.

[0123] Furthermore, a storage compartment maintenance opening is provided on the sample storage compartment 1, and a maintenance door 7 is provided inside the storage compartment maintenance opening. The maintenance door 7 can open and close the storage compartment maintenance opening, and when the maintenance door 7 is opened, the inside of the sample storage compartment 1 can be maintained.

[0124] Preferably, by providing the maintenance door 7, when a fault occurs inside the sample storage compartment 1, the maintenance door 7 can be quickly opened for maintenance, and the fast rotating storage rack assembly 11 can be maintained.

[0125] Furthermore, a display control device 8 is also provided on the sample storage compartment 1, and the display control device 8 can display the internal parameters of the sample storage compartment 1 and adjust and control the work.

[0126] Preferably, by providing the display control device 8, commands can be issued to make the equipment work, and the progress of each equipment can be displayed in real time, such as displaying the internal temperature, or displaying the position of the sample boxes on the rotating storage rack assembly 11, etc.

[0127] In summary, the utility model can achieve the automatic adjustable technology from 5°C to -150°C by providing a liquid storage tank at the bottom of the Stirling refrigeration mechanism 32, injecting a certain amount of liquid nitrogen at one time and sealing it; adding a certain amount of liquid nitrogen into the storage cavity 323 at one time and sealing it, starting the Stirling refrigeration mechanism 32, the cold head 322 at one end of the Stirling refrigeration mechanism 32 generates a cold source, the liquid nitrogen in the storage cavity 323 vaporizes and rises to one end of the cold head 322 of the Stirling, cools and liquefies when encountering the cold head 322 of the Stirling refrigeration mechanism 32, and the liquid automatically stores downward, running automatically in a cycle to achieve the effect of balanced heat conduction and refrigeration; adopting a high-pressure bearing cold head 322 and a storage cavity 323 of a high-pressure bearing stainless steel shaft body to form a high-pressure cavity without pressure relief; due to the high-pressure boiling point difference, the liquefaction ability is improved and the liquid sinks quickly for balanced cooling; filling the liquid once can be used for a lifetime, whether the power is turned on or not, or during storage, the gas vaporized from liquid nitrogen and the like is automatically compressed in the cavity without affecting the safe long-term storage; it is very easy to replace, upgrade, clean and disinfect; the power consumption is low and the energy is saved by 50%.

[0128] Importantly, it should be noted that the construction and arrangement of the present application shown in multiple different exemplary embodiments are merely illustrative. Although only a few embodiments are described in detail in this disclosure, those who refer to this disclosure should easily understand that many modifications are possible on the premise of substantially not deviating from the novel teachings and advantages of the subject matter described in this application (for example, the dimensions, scales, structures, shapes and proportions of various components, and parameter values (such as temperature, pressure, etc.), installation arrangements, use of materials, changes in color, orientation, etc.). For example, an element shown as integrally formed may be composed of multiple parts or elements, the position of the element may be inverted or otherwise changed, and the nature, number or position of discrete elements may be changed or altered. Therefore, all such modifications are intended to be included within the scope of the present utility model. The order or sequence of any process or method steps may be changed or reordered according to alternative embodiments. In the claims, any "means-plus-function" clause is intended to cover the structure that performs the recited function herein, and not only structural equivalents but also equivalent structures. Other substitutions, modifications, changes and omissions may be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the present utility model. Therefore, the present utility model is not limited to specific embodiments, but extends to various modifications that still fall within the scope of the appended claims.

[0129] In addition, in order to provide a concise description of the exemplary embodiments, not all features of the actual embodiments may be described (i.e., those features that are not relevant to the currently considered best mode of implementing the present utility model, or those features that are not relevant to the implementation of the present utility model).

[0130] It should be understood that in the development of any actual implementation, such as in any engineering or design project, a large number of specific implementation decisions can be made. Such development efforts may be complex and time-consuming, but for those of ordinary skill in the art who benefit from this disclosure, without undue experimentation, such development efforts will be routine work of design, manufacture, and production.

[0131] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit them. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the spirit and scope of the technical solutions of the present invention, and they should all be covered within the scope of the claims of the present invention.

Claims

1. A biological sample low-temperature storage refrigerator, characterized in that: The sample storage chamber (1) comprises a sample storage chamber (1), an operation area (2), and a refrigeration mechanism (3); the sample storage chamber (1) is provided with an operation area (2) on its side, the sample storage chamber (1) is provided with a refrigeration mechanism (3), and the refrigeration mechanism (3) can refrigerate the sample storage chamber (1); the operation area (2) can store and retrieve samples in the sample storage chamber (1), and the sample storage chamber (1) can store basket samples; A lifting shovel mechanism (21) is provided in the operation area (2), and the lifting shovel mechanism (21) can grab and transport the sample box.

2. The biological sample low-temperature storage refrigerator according to claim 1, characterized in that: The lifting shovel mechanism (21) includes an angle adjustment component and a grabbing component; the angle adjustment component can perform at least one level of rotation, and a grabbing component is arranged on the angle adjustment component. The angle adjustment component can drive the grabbing component to turn, and the grabbing component can scoop and store the sample box inside the sample storage chamber (1).

3. The biological sample low-temperature storage refrigerator according to claim 2, characterized in that: The grabbing assembly comprises a supporting telescopic member (2121) and a grabbing member (2122); the supporting telescopic member (2121) can drive the grabbing member (2122) to move horizontally, and the sample box can be scooped through the grabbing member (2122).

4. The biological sample low-temperature storage refrigerator according to claim 3, characterized in that: The grabbing assembly further comprises a guide and limit frame (2123), wherein the guide and limit frame (2123) is connected to the supporting telescopic member (2121), and the guide and limit frame (2123) can clamp the grabbing member (2122).

5. The biological sample low-temperature storage refrigerator according to claim 4, characterized in that: The supporting telescopic member (2121) comprises a supporting plate (21211), a first driving member (21212), and a first follower (21213); one end of the supporting plate (21211) is connected to the angle adjustment component, the first driving member (21212) is arranged on the supporting plate (21211), the first follower (21213) is arranged on the side of the first driving member (21212), the front end of the first follower (21213) is connected to the grabbing member (2122), the first driving member (21212) can drive the first follower (21213) to move horizontally along the supporting plate (21211), and the first follower (21213) can drive the grabbing member (2122) to move horizontally.

6. The biological sample low-temperature storage refrigerator according to claim 5, characterized in that: The grasping member (2122) comprises a supporting clamp (21221), an elastic telescopic member (21222), and a guide end (21223); the first follower member (21213) is provided with elastic telescopic members (21222) on both sides of the front end, the supporting clamp (21221) is provided on the side of the elastic telescopic member (21222), and the outer side of the supporting clamp (21221) is provided with a guide end (21223), and the guide end (21223) can guide the supporting clamp (21221) to enter the guide limit frame (2123).

7. The biological sample low-temperature storage refrigerator according to claim 6, characterized in that: The two groups of support clamps (21221) can move away from each other or towards each other, and the support clamps (21221) can clamp or release the plate frame.

8. The biological sample low-temperature storage refrigerator according to claim 5, characterized in that: The first follower (21213) can pass through the guide limit frame (2123) to be connected with the grabbing member (2122).

9. The biological sample low-temperature storage refrigerator according to claim 2, characterized in that: The angle adjustment component includes a primary rotating part, a secondary rotating part, and a tertiary rotating part; the two sides of the secondary rotating part are respectively connected to the primary rotating part and the tertiary rotating part, one end of the tertiary rotating part is connected to the grabbing component, and the primary rotating part, the secondary rotating part, and the tertiary rotating part can all rotate at different angles.

10. The biological sample low-temperature storage refrigerator according to claim 2, characterized in that: It also comprises a vertical driving mechanism (213), on which an angle adjustment component is arranged, and the vertical driving mechanism (213) can drive the angle adjustment component and the grabbing component to move up and down.

11. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: The refrigeration mechanism (3) is a compressor refrigeration mechanism (31) or a Stirling refrigeration mechanism (32); the Stirling refrigeration mechanism (32) is arranged at the upper end of the sample storage compartment (1); and the compressor refrigeration mechanism (31) is arranged at the side end of the sample storage compartment (1).

12. The biological sample low-temperature storage refrigerator according to claim 11, characterized in that: The compressor refrigeration mechanism (31) is provided with a ventilation mechanism (33), and the ventilation mechanism (33) can ventilate the compressor refrigeration mechanism (31). The compressor refrigeration mechanism (31) is also provided with a maintenance port, and the compressor refrigeration mechanism (31) can be maintained through the maintenance port.

13. The biological sample low-temperature storage refrigerator according to claim 12, characterized in that: The ventilation mechanism (33) comprises an exhaust member (331) and a pipe (332); the exhaust member (331) is arranged in the pipe (332); one end of the pipe (332) is connected to the compressor refrigeration mechanism (31), and the other end passes through the operating area (2) and leads to the outside of the operating area (2).

14. The biological sample low-temperature storage refrigerator according to claim 11, characterized in that: The Stirling refrigeration mechanism (32) comprises a Stirling refrigeration module (321), a cold head (322), and a storage cavity (323); the lower end of the Stirling refrigeration module (321) is connected to the cold head (322), the storage cavity (323) and the Stirling refrigeration module (321) are detachably connected, and the cold head (322) is arranged inside the storage cavity (323); liquid nitrogen can be stored in the storage cavity (323), and the cold head (322) can liquefy vaporized nitrogen.

15. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: The sample storage cabin (1) is also provided with a revolving door assembly (4), and the revolving door assembly (4) is arranged inside the operating area (2), and the revolving door assembly (4) can open and close the scooping channel.

16. The biological sample low-temperature storage refrigerator according to claim 15, characterized in that: The revolving door assembly (4) comprises a revolving door driving member (41) and a revolving door (42); the lower end of the revolving door driving member (41) is connected to the revolving door (42), and the revolving door driving member (41) can drive the revolving door (42) to open and close the scooping channel.

17. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: A rotatable storage rack assembly (11) is arranged in the sample storage compartment (1), and the rotatable storage rack assembly (11) can store and retrieve sample boxes.

18. The biological sample low-temperature storage refrigerator according to any one of claims 1 to 10, characterized in that: A transfer port is arranged on the side of the operation area (2), and a transfer door (29) is arranged in the transfer port. The transfer door (29) can be opened and closed by the transfer port.

19. The biological sample low-temperature storage refrigerator according to claim 18, characterized in that: A code scanning mechanism (5) is arranged on the side of the transfer door (29), and the code scanning mechanism (5) can scan the code of the sample box.

20. The biological sample low-temperature storage refrigerator according to claim 17, characterized in that: The sample storage compartment (1) is provided with a storage compartment inspection opening, and an inspection door (7) is arranged inside the storage compartment inspection opening. The inspection door (7) can be opened and closed to inspect the interior of the sample storage compartment (1).

21. The biological sample low-temperature storage refrigerator according to claim 20, characterized in that: The sample storage chamber (1) is also provided with a display control device (8), and the display control device (8) can display the internal parameters of the sample storage chamber (1) and adjust the control work.

Citation Information

Patent Citations

  • Full-automatic sample low-temperature storing and taking system

    CN116409573A