Fermentation tank for biological pharmacy
By designing a biopharmaceutical fermentation tank including a rotating assembly and a gas supply assembly, the problems of insufficient contact between gas and liquid materials and material adhesion in the prior art are solved, and the fermentation speed is improved and the thoroughness of discharge is achieved.
Patent Information
- Application Number
- CN202422052882.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-23
- Publication Date
- 2025-06-20
- Estimated Expiration
- 2034-08-23
AI Technical Summary
During the fermentation process of existing biofermentation tanks, it is difficult for gas to fully contact with the liquid material, resulting in slow fermentation speed. At the same time, the fermented liquid is prone to adhere to the inner wall of the tank, resulting in insufficient discharge of materials.
A biopharmaceutical fermentation tank including a tank body and a rotating assembly is designed. The rotating assembly realizes sufficient contact between gas and material through a rotating disc, a scraping assembly and a gas supply assembly, and prevents material from adhering to the inner wall of the tank body through the scraping assembly.
Through the cooperation of the rotating assembly and the gas supply assembly, the gas makes full contact with the material, significantly speeding up the fermentation speed, and effectively avoiding material adhesion by scraping the assembly, ensuring thoroughness of the discharge.
Smart Images
Figure CN223002924U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of fermentation tanks and relates to a fermentation tank for biopharmaceuticals. Background Art
[0002] Most of the current drugs contain organic components, which need to be obtained through microbial fermentation. Therefore, fermentation tanks are used in current drug production. A fermentation tank is a device for microbial fermentation and can produce organic substances such as antibiotics, amino acids, organic acids, and vitamins. When microorganisms ferment, stirring is required. Stirring can mix air with the fermentation broth, promote the dissolution of oxygen in the fermentation broth, ensure the supply for the growth and reproduction of microorganisms, and thus improve the fermentation efficiency of the fermentation tank. The main body of a fermentation tank is generally a columnar cylinder made of stainless steel plates. In design and processing, attention should be paid to strict and reasonable structure, being able to withstand steam sterilization, having a certain operating flexibility, minimizing internal accessories (to avoid dead corners), having strong material and energy transfer performance, and being able to be adjusted to facilitate cleaning, reduce pollution, be suitable for the production of various products, and reduce energy consumption.
[0003] Existing biological fermentation tanks generally transport gas to the inside of the biological fermentation tank from the bottom to make the gas fully contact with the liquid material inside the biological fermentation tank. However, the rising position of the gas is relatively fixed, and it is difficult for the gas to fully contact and mix with the liquid material inside the biological fermentation tank, resulting in a slower fermentation speed. At the same time, the liquid after fermentation in the existing fermentation tank for biopharmaceuticals is likely to adhere to the inner wall of the fermentation tank, resulting in incomplete discharging. Therefore, we propose a fermentation tank for biopharmaceuticals. Summary of the Utility Model
[0004] The purpose of the utility model is to address the above problems existing in the current technology and propose a fermentation tank for biopharmaceuticals. The technical problem to be solved by this device is: how to improve the fermentation speed of the biological fermentation tank.
[0005] The purpose of the utility model can be achieved by the following technical solutions:
[0006] A fermentation tank for biopharmaceuticals includes a tank body and a rotating assembly. The rotating assembly includes a cover plate arranged above the tank body. A rotating disk is rotatably arranged on the cover plate. A belt groove is formed on the side surface of the rotating disk. A U-shaped plate is fixed above the cover plate. A rotating motor is fixed above the U-shaped plate. A pulley is fixed on the output shaft of the rotating motor. A belt is arranged between the pulley and the rotating disk. A rotating shaft is fixed below the rotating disk. A hollow cavity is formed inside the rotating shaft. A plurality of air holes are arranged at the lower end of the rotating shaft. A scraping assembly is arranged on the rotating disk. A gas supply assembly is arranged below the tank body.
[0007] An annular groove is formed on the inner wall of the tank body. A discharge pipe is arranged below the tank body, and a control valve is arranged on the discharge pipe. A plurality of legs are fixed below the tank body.
[0008] With the above structure, when the control valve is opened, the discharge pipe discharges the materials inside the tank body. The plurality of legs can support the tank body, and the annular groove provides a suspended position for the scraping assembly.
[0009] The scraping assembly includes two multi-stage electric push rods. Both multi-stage electric push rods are fixed above the rotating disc. Connecting rods are fixed to the ends of both multi-stage electric push rods. Two telescopic bellows are arranged between the rotating disc and the connecting rods. The ends of both multi-stage electric push rods are located inside the corresponding telescopic bellows. An installation ring is fixed between the two connecting rods, and the installation ring is sleeved on the rotating shaft.
[0010] With the above structure, when the two multi-stage electric push rods extend, they drive the connecting rods to descend. The connecting rods drive the installation ring to descend. At the same time, the connecting rods drive the telescopic bellows to extend, and the telescopic bellows can protect the multi-stage electric push rods.
[0011] Hanging rings are fixed on the two connecting rods. Rubber scraping strips are arranged on the hanging rings. The rubber scraping strips are in contact with the inner wall of the tank body. A separation net is arranged inside the hanging rings.
[0012] With the above structure, the two connecting rods drive the hanging rings to descend. The rubber scraping strips scrape the inner wall of the tank body. The separation net can decompose the gas bubbles, enabling the gas to come into full contact with the materials.
[0013] The air supply assembly includes a rotary joint, an air pump, and a rotating box. The rotary joint is rotatably arranged at the bottom of the tank body. The air pump is fixed at the bottom of the tank body. The air outlet end of the air pump is connected to the rotary joint through an air delivery pipe. The rotating box is fixed at the lower end of the rotating shaft, and the rotating box is communicated with the hollow cavity of the rotating shaft. A plurality of air holes are formed in the upper part and both ends of the rotating box, and the rotating box is rotatably connected to the rotary joint.
[0014] With the above structure, the air pump transports the gas through the air delivery pipe into the interior of the rotary joint. The rotary joint transports the gas into the interior of the rotating box. The rotating box transports the gas into the materials through a plurality of air holes.
[0015] Compared with the prior art, the fermentation tank for biopharmaceuticals has the following advantages:
[0016] 1. Through the cooperation of the rotating assembly and the air supply assembly, the air pump transports the gas through the air delivery pipe into the interior of the rotary joint. The rotary joint transports the gas into the interior of the rotating box. The rotating box transports the gas into the materials through a plurality of air holes. The separation net can decompose the gas bubbles, enabling the gas to come into full contact with the materials and accelerating the fermentation speed;
[0017] 2. The tank body and the scraping assembly cooperate. The two multi-stage electric push rods extend to drive the connecting rod to descend. The connecting rod drives the mounting ring to descend. At the same time, the connecting rod drives the telescopic bellows to extend. The telescopic bellows can protect the multi-stage electric push rod. The two connecting rods drive the hanging ring to descend, and the hanging ring scrapes the inner wall of the tank body to prevent materials from adhering to the inner wall of the tank body during discharging. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 is a three-dimensional structural schematic diagram of the present utility model;
[0019] Figure 2 is a front structural schematic diagram of the present utility model;
[0020] Figure 3 is a sectional structural schematic diagram of the present utility model;
[0021] Figure 4 is an internal structural schematic diagram of the present utility model;
[0022] In the figure: 1, rotating disk; 2, cover plate; 3, tank body; 4, leg; 5, belt; 6, belt pulley; 7, U-shaped plate; 8, rotating motor; 9, multi-stage electric push rod; 10, control valve; 11, discharge pipe; 12, rotating joint; 13, air pump; 14, connecting rod; 15, rotating box; 16, rotating shaft; 17, telescopic bellows; 18, mounting ring; 19, hanging ring; 20, separation net. DETAILED DESCRIPTION OF THE EMBODIMENTS
[0023] The technical solutions of this patent will be further described in detail below in conjunction with the specific embodiments.
[0024] The embodiments of this patent are described in detail below. The examples of the embodiments are shown in the drawings, where the same or similar reference numerals represent the same or similar elements or elements with the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are only used to explain this patent and should not be construed as a limitation of this patent.
[0025] In the description of this patent, it should be understood that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing this patent and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this patent.
[0026] In the description of this patent, it should be noted that unless otherwise clearly specified and defined, the terms "installation", "connection", "linkage", and "setting" should be understood in a broad sense. For example, it can be fixedly connected and set, or detachably connected and set, or integrally connected and set. For those of ordinary skill in the art, the specific meanings of the above terms in this patent can be understood according to specific circumstances.
[0027] Please refer to Figures 1-4 , this embodiment provides a fermentation tank for biopharmaceuticals, including a tank body 3 and a rotating assembly. The rotating assembly includes a cover plate 2, the cover plate 2 is arranged above the tank body 3, a rotating disc 1 is rotatably arranged on the cover plate 2, a belt groove is formed on the side surface of the rotating disc 1, a U-shaped plate 7 is fixed above the cover plate 2, a rotating motor 8 is fixed above the U-shaped plate 7, a pulley 6 is fixed on the output shaft of the rotating motor 8, a belt 5 is arranged between the pulley 6 and the rotating disc 1, a rotating shaft 16 is fixed below the rotating disc 1, a hollow cavity is formed inside the rotating shaft 16, a plurality of air holes are arranged at the lower end of the rotating shaft 16, a scraping assembly is arranged on the rotating disc 1, and a gas supply assembly is arranged below the tank body 3.
[0028] An annular groove is formed on the inner wall of the tank body 3, a discharge pipe 11 is arranged below the tank body 3, a control valve 10 is arranged on the discharge pipe 11, and a plurality of legs 4 are fixed below the tank body 3; when the control valve 10 is opened, the discharge pipe 11 discharges the materials inside the tank body 3, and the plurality of legs 4 can support the tank body 3, and the annular groove provides a suspended position for the scraping assembly.
[0029] The scraping assembly includes two multi-stage electric push rods 9, both of the two multi-stage electric push rods 9 are fixed above the rotating disc 1, connecting rods 14 are fixed at the ends of the two multi-stage electric push rods 9, two telescopic bellows 17 are arranged between the rotating disc 1 and the connecting rods 14, the ends of the two multi-stage electric push rods 9 are located inside the corresponding telescopic bellows 17, and a mounting ring 18 is fixed between the two connecting rods 14, and the mounting ring 18 is sleeved on the rotating shaft 16; when the two multi-stage electric push rods 9 extend, the connecting rods 14 are driven to descend, the connecting rods 14 drive the mounting ring 18 to descend, and at the same time, the connecting rods 14 drive the telescopic bellows 17 to extend, and the telescopic bellows 17 can protect the multi-stage electric push rods 9.
[0030] Hanging rings 19 are fixed on the two connecting rods 14, rubber scraping strips are arranged on the hanging rings 19, and the rubber scraping strips are in contact with the inner wall of the tank body 3, and a separation net 20 is arranged inside the hanging rings 19; when the two connecting rods 14 drive the hanging rings 19 to descend, the rubber scraping strips scrape the inner wall of the tank body 3, and the separation net 20 can decompose the bubbles of the gas, so that the gas is in full contact with the materials.
[0031] The air supply assembly includes a rotary joint 12, an air pump 13 and a rotary box 15. The rotary joint 12 is rotatably arranged at the bottom of the tank body 3. The air pump 13 is fixed at the bottom of the tank body 3. The air outlet end of the air pump 13 is connected to the rotary joint 12 through an air delivery pipe. The rotary box 15 is fixed at the lower end of the rotary shaft 16. The rotary box 15 is communicated with the hollow cavity of the rotary shaft 16. A plurality of air holes are formed above, at both ends of the rotary box 15. The rotary box 15 is rotatably connected to the rotary joint 12. The air pump 13 conveys gas to the inside of the rotary joint 12 through the air delivery pipe. The rotary joint 12 conveys the gas to the inside of the rotary box 15. The rotary box 15 conveys the gas to the inside of the material through a plurality of air holes.
[0032] The working principle of the present utility model:
[0033] The rotary motor 8 drives the pulley 6 to rotate through the output shaft. The pulley 6 drives the rotating disk 1 to rotate through the belt 5. The rotating disk 1 drives the rotary shaft 16 to rotate. The rotary shaft 16 drives the rotary box 15 to rotate. The air pump 13 conveys gas to the inside of the rotary joint 12 through the air delivery pipe. The rotary joint 12 conveys the gas to the inside of the rotary box 15 and the hollow cavity. The rotary box 15 and the hollow cavity convey the gas to the inside of the material through a plurality of air holes, so as to make the gas and the material fully contact and accelerate the fermentation speed.
[0034] The rotating disk 1 drives the two multi-stage electric push rods 9 to rotate. The two multi-stage electric push rods 9 extend to drive the connecting rod 14 to descend. The connecting rod 14 drives the mounting ring 18 to descend. At the same time, the connecting rod 14 drives the telescopic bellows 17 to extend. The telescopic bellows 17 can protect the multi-stage electric push rod 9. The two connecting rods 14 drive the hanging ring 19 to descend. The hanging ring 19 scrapes the inner wall of the tank body 3 to prevent the material from adhering to the inner wall of the tank body 3. At the same time, the separation net 20 can decompose the gas bubbles, so that the gas and the material are fully contacted and the fermentation speed is accelerated.
[0035] After fermentation is completed, the control valve 10 is opened, and the discharge pipe 11 discharges the material inside the tank body 3.
[0036] The above has described the preferred embodiments of this patent in detail, but this patent is not limited to the above embodiments. Within the scope of knowledge possessed by those of ordinary skill in the art, various changes can be made without departing from the gist of this patent.
Claims
1. A biopharmaceutical fermentation tank, comprising a tank body (3) and a rotating assembly, characterized in that: The rotating assembly comprises a cover plate (2), the cover plate (2) being arranged above the tank body (3), a rotating disk (1) being rotatably arranged on the cover plate (2), a belt groove being provided on the side of the rotating disk (1), a U-shaped plate (7) being fixed above the cover plate (2), a rotating motor (8) being fixed above the U-shaped plate (7), a belt pulley (6) being fixed on the output shaft of the rotating motor (8), a belt (5) being provided between the belt pulley (6) and the rotating disk (1), a rotating shaft (16) being fixed below the rotating disk (1), a hollow cavity being provided inside the rotating shaft (16), a plurality of air holes being provided at the lower end of the rotating shaft (16), a scraping assembly being provided on the rotating disk (1), and an air supply assembly being provided below the tank body (3).
2. A biopharmaceutical fermentation tank according to claim 1, characterized in that: The inner wall of the tank body (3) is provided with an annular groove, a discharge pipe (11) is arranged below the tank body (3), a control valve (10) is arranged on the discharge pipe (11), and a plurality of legs (4) are fixed below the tank body (3).
3. A biopharmaceutical fermentation tank according to claim 1, characterized in that: The scraping assembly comprises two multi-stage electric push rods (9), the two multi-stage electric push rods (9) are both fixed above the rotating disk (1), the ends of the two multi-stage electric push rods (9) are both fixed with connecting rods (14), two telescopic bellows (17) are arranged between the rotating disk (1) and the connecting rod (14), the ends of the two multi-stage electric push rods (9) are both located inside the telescopic bellows (17) at corresponding positions, and a mounting ring (18) is fixed between the two connecting rods (14), and the mounting ring (18) is sleeved on the rotating shaft (16).
4. A biopharmaceutical fermentation tank according to claim 3, characterized in that: A hanging ring (19) is fixed on the two connecting rods (14), a rubber scraper is arranged on the hanging ring (19), the rubber scraper abuts against the inner wall of the tank body (3), and a separation net (20) is arranged inside the hanging ring (19).
5. A biopharmaceutical fermentation tank according to claim 1, characterized in that: The air supply assembly comprises a rotating joint (12), an air pump (13) and a rotating box (15); the rotating joint (12) is rotatably arranged at the bottom of the tank body (3); the air pump (13) is fixed at the bottom of the tank body (3); the air outlet of the air pump (13) is connected to the rotating joint (12) through an air delivery pipe; the rotating box (15) is fixed at the lower end of the rotating shaft (16); the rotating box (15) is connected to the hollow cavity of the rotating shaft (16); a plurality of air holes are provided on the top and both ends of the rotating box (15); and the rotating box (15) is rotatably connected to the rotating joint (12).