Centrifugal cup fixing device

By designing a centrifugal cup fixing device including a rotary clamp assembly and thermally conductive metal side wall, the problems of centrifugal cup jitter and heat conduction in the prior art are solved, and stable and precise cell separation and uniform temperature control are achieved.

CN223010627UActive Publication Date: 2025-06-24BEIJING BANGNING INTELLIGENT BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422200810.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-09
Publication Date
2025-06-24
Estimated Expiration
2034-09-09

AI Technical Summary

Technical Problem

The existing centrifugal cup fixing device has jitter problems during operation, and it is difficult to achieve rapid, stable and uniform heat conduction, affecting cell separation accuracy and cell activity.

Method used

A centrifugal cup fixing device including a base and a rotary buckle assembly is designed. The centrifugal cup and the base are snapped into one through the rotary buckle assembly to achieve circumferential, axial and radial constraints of the centrifugal cup, and contact heat conduction is carried out through the metal side wall with good thermal conductivity.

Benefits of technology

It effectively prevents the jitter of the centrifugal cup during operation, improves the separation accuracy and cell viability, and avoids fogging of the centrifugal cup through uniform heat conduction, improving the efficiency of cell culture.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a centrifugal cup fixing device which comprises a base and further comprises a rotary buckling assembly used for connecting a centrifugal cup and the base, and the rotary buckling assembly is used for connecting the centrifugal cup and the base into a whole in a clamping mode after the centrifugal cup rotates to a preset angle relative to the base. The base is provided with a centrifugal cup containing cavity, and when the centrifugal cup and the base are connected into a whole, the peripheral side wall of the centrifugal cup containing cavity wraps the outer side of a cup body of the centrifugal cup. The centrifugal cup can be kept stable all the time in the operation process, and rapid, stable and uniform heat conduction can be conducted on the centrifugal cup.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell processing, in particular to a centrifuge cup fixing device. Background Technique

[0002] A centrifuge tube is a container used in laboratories for centrifugally separating cells and other biological materials. They are commonly used in centrifuges to separate biological molecules such as cells of different densities, cell debris, proteins, nucleic acids, etc. When the centrifuge rotates, it generates an outward force that is proportional to the mass of the object, the radius of rotation, and the square of the rotational speed. This force causes the heavier particles to move towards the bottom of the centrifuge tube, while the lighter particles remain at the top. Particles of different sizes and densities settle at different speeds under the action of centrifugal force. Larger or denser particles settle faster, while smaller or less dense particles settle more slowly. By adjusting the rotational speed and centrifugation time of the centrifuge, the settling speed of the particles can be controlled, thereby achieving the separation of different particles. For example, by setting appropriate centrifugation conditions, cell nuclei, mitochondria, cytoplasm, and other cell components can be separated. In addition, in some experiments, heat may be generated during the centrifugation process, affecting the stability of the sample. Therefore, some centrifuges are equipped with a temperature control system to maintain a constant temperature of the sample during centrifugation.

[0003] Existing cell centrifugation devices, although achieving the centrifugation function required for cell separation, still have certain deficiencies:

[0004] (1) The installation structure of the centrifuge cup in the centrifugation device cannot achieve sufficient precision and reliability in restricting the lateral and longitudinal positions of the centrifuge cup, and the centrifuge cup is prone to jitter during operation. Disposable centrifuge cups used for cell separation are generally made of industrial plastics such as polyethylene (PE), polypropylene (PP), polyvinyl chloride (PVC), polystyrene (PS), polycarbonate (PC), etc. to meet the requirement of single use. However, under high-speed centrifugation, problems such as conical swing and torsional deformation may occur in the centrifuge cup, resulting in large vibrations, reduced separation precision, and further affecting the activity and quantity of cells, etc. More seriously, the cup may even break away from the mounting base, causing work accidents.

[0005] (2) When culturing cells in a centrifuge cup, it is generally necessary to maintain the temperature of the centrifuge cup at 37°C ± 0.5°C. However, when automatically harvesting cells and cleaning the culture medium, it is desired to maintain the temperature of the centrifuge cup at 2°C to 8°C. That is, in some cases, the centrifuge cup needs to be maintained within a relatively stable temperature range after heating or cooling. In particular, the temperature range requirements for cell culture are more stringent. When using a disposable centrifuge cup for automatic cell culture or cell cleaning, the general method of maintaining the temperature is to heat the entire cavity of the centrifuge cup, and the heat is conducted through the air in the middle. When the heat is transferred to the centrifuge cup, there will be a relatively large temperature difference between the part with liquid and the part without liquid in the centrifuge cup, resulting in fogging of the centrifuge cup, affecting the nutrient components and concentration ratio of the cell culture medium, and further lengthening the culture time or even causing culture failure.

[0006] Therefore, how to improve the connection stability and reliability between the centrifuge cup and the mounting structure, and how to conduct rapid, stable and uniform heat transfer to the centrifuge cup are technical problems that need to be solved urgently by those skilled in the art. Summary of the Utility Model

[0007] In order to overcome the deficiencies of the prior art, the present utility model provides a centrifuge cup fixing device, which can keep the centrifuge cup stable during operation and can conduct rapid, stable and uniform heat transfer to the centrifuge cup.

[0008] In order to achieve at least one of the above purposes, the technical solutions adopted by the present utility model are as follows:

[0009] The present utility model provides a centrifuge cup fixing device, which includes a base, and further includes a rotary snap-fit assembly for connecting the centrifuge cup and the base. The rotary snap-fit assembly is used to snap the centrifuge cup and the base together after the centrifuge cup rotates relative to the base to a preset angle.

[0010] Preferably, the rotary snap-fit assembly includes several groups of cooperating snap-fit protrusions and snap-fit grooves. One of the centrifuge cup and the base is provided with snap-fit protrusions, and the other is provided with snap-fit grooves; the snap-fit grooves include a circumferential limiting groove for unidirectionally limiting the rotation of the snap-fit protrusions and an axial guiding groove perpendicular to and connected to the circumferential limiting groove for guiding the snap-fit protrusions into the circumferential limiting groove.

[0011] Preferably, the base is provided with an axial mounting hole, and the base is fixedly connected to the output shaft of the centrifugal mechanism entering the axial mounting hole through a fastener.

[0012] Preferably, the base is further provided with several perspective windows.

[0013] Preferably, the axial mounting hole is provided with a limiting rib for forming an interference fit with the output shaft of the centrifugal mechanism.

[0014] Preferably, a centrifuge cup accommodating cavity is provided on the base. When the centrifuge cup and the base are integrally connected, the circumferential side wall of the centrifuge cup accommodating cavity wraps the outer side of the cup body of the centrifuge cup.

[0015] Preferably, the circumferential side wall of the centrifuge cup accommodating cavity wraps part or the whole of the cup body of the centrifuge cup.

[0016] Preferably, the circumferential side wall of the centrifuge cup accommodating cavity is made of a metal material with good heat conduction performance.

[0017] Preferably, when the centrifuge cup and the base are integrally connected, the inner bottom surface of the centrifuge cup accommodating cavity abuts against the centrifuge cup, and the snap projection abuts against the snap groove.

[0018] Preferably, a recessed groove is formed at the connection between the circumferential side wall and the bottom surface of the centrifuge cup accommodating cavity.

[0019] Preferably, the base includes a fixed seat and a mounting seat. The centrifuge cup accommodating cavity is arranged on the fixed seat. The mounting seat is coaxially connected to the fixed seat, and the groove is arranged on the mounting seat.

[0020] Preferably, the fixed seat and the mounting seat are integrally formed or are independent components.

[0021] Preferably, the outer contour of the fixed seat is in an inverted convex shape, and its internal cavity includes the centrifuge cup accommodating cavity and the mounting seat accommodating cavity.

[0022] Positive effects of the present utility model: Compared with the prior art, the centrifuge cup fixing device provided by the present utility model includes a rotary snap-fit component for fixedly connecting the centrifuge cup and the base. When the centrifuge cup is placed into the base, the centrifuge cup is rotated forward to a preset angle, and the rotary snap-fit component clamps the centrifuge cup and the base into an integral body, thereby enabling the rotary snap-fit component to limit the circumferential and axial movements of the centrifuge cup (i.e., simultaneously performing position constraints on the horizontal and vertical directions of the centrifuge cup); at the same time, the circumferential side wall of the base accommodating cavity wraps the centrifuge cup to limit the radial movement of the centrifuge cup. Thus, the circumferential, axial, and radial directions of the centrifuge cup are all restricted, enabling the centrifuge cup to always remain stable during operation, thereby ensuring the separation accuracy and cell viability. On the contrary, the centrifuge cup is rotated backward to a preset angle, and then the centrifuge cup is pulled out axially to disassemble the centrifuge cup from the base.

[0023] In addition, by wrapping the centrifuge cup with a metal side wall with good heat conduction performance and controlling the temperature of the metal side wall, contact heat conduction between the metal side wall and the centrifuge cup can be achieved. Compared with the existing air heat transfer method, the uniformity of maintaining the target temperature of the centrifuge cup can be improved, and when culturing cells, fogging of the centrifuge cup can also be avoided.

[0024] In summary, the utility model can effectively ensure the reliable stability of the connection between the centrifuge cup and the base, enable the centrifuge cup to always remain stable during operation, and can conduct rapid, stable, and uniform heat transfer to the centrifuge cup. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only the embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on the provided drawings.

[0026] Figure 1 is a schematic structural diagram of a centrifuge cup fixing device provided by the first specific embodiment of the present utility model;

[0027] Figure 2 is a schematic structural diagram of the centrifuge cup fixing device provided by the first specific embodiment of the present utility model from another angle;

[0028] Figure 3 is a schematic cross-sectional structural diagram of the centrifuge cup fixing device provided by the first specific embodiment of the present utility model;

[0029] Figure 4 is a schematic structural diagram of a centrifuge cup provided by the present utility model;

[0030] Figure 5 is a schematic cross-sectional structural diagram of the combination of the centrifuge cup fixing device and the centrifuge cup provided by the first specific embodiment of the present utility model;

[0031] Figure 6 is an exploded structural diagram of the centrifuge cup fixing device and the centrifuge cup provided by the first specific embodiment of the present utility model;

[0032] Figure 7 is an exploded structural diagram of the centrifuge cup fixing device provided by the second specific embodiment of the present utility model;

[0033] Figure 8 is a schematic cross-sectional structural diagram of the centrifuge cup fixing device provided by the third specific embodiment of the present utility model;

[0034] Figure 9 is a schematic cross-sectional structural diagram of the centrifuge cup fixing device provided by the fourth specific embodiment of the present utility model;

[0035] Figure 10 is a schematic cross-sectional structural diagram of the centrifuge cup fixing device provided by the fifth specific embodiment of the present utility model;

[0036] Figure 11 It is a schematic structural diagram of a centrifuge cup fixing device provided by the sixth specific embodiment of the present utility model;

[0037] Figure 12 It is a schematic structural diagram of a centrifuge cup fixing device provided by the seventh specific embodiment of the present utility model.

[0038] The reference numerals are as follows:

[0039] Base 1, centrifuge cup 2, fixing seat 3, mounting seat 4;

[0040] Snap protrusion 21, convex ring 22;

[0041] Centrifuge cup accommodating cavity 311, circumferential side wall 312, bottom surface 313, rounded corner recess 314, notch recess 315, perspective window 316, mounting seat accommodating cavity 317, buffer gasket 318;

[0042] Snap groove 41, axial mounting hole 42;

[0043] Axial guiding groove 411, circumferential limiting groove 412, snap - mating surface 413;

[0044] Limiting rib 421, locking hole 422, through - hole 423. Detailed implementation manners

[0045] Next, the accompanying drawings in the embodiments of the present utility model will be used to clearly and completely describe the prior art and the technical solutions in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.

[0046] The preferred embodiments of the present utility model will be described in detail below with reference to the accompanying drawings.

[0047] Referring to Figures 1 to 6 , the first embodiment of the present utility model provides a centrifuge cup fixing device, including a base 1, which is used to connect and fix the centrifuge cup 2 and is also connected to the output shaft of the centrifugal mechanism. When the centrifugal mechanism works, the combination of the base 1 and the centrifuge cup 2 rotates with the rotation of the output shaft (rotation axis) of the centrifugal mechanism.

[0048] In order to ensure the stable and reliable combined installation of the centrifuge cup 2 on the base 1, the centrifuge cup fixing device further includes a rotary snap - fit assembly for connecting the centrifuge cup 2 and the base 1. When the centrifuge cup 2 is inserted into the base 2, the rotary snap - fit assembly is used to snap - connect the centrifuge cup 2 and the base 1 together after the centrifuge cup 2 rotates relative to the base 1 to a preset angle. The preset angle here refers to the maximum rotation angle that the centrifuge cup 2 can rotate relative to the base 1.

[0049] In the first embodiment, two sets of rotary snap - fit assemblies are provided between the centrifuge cup 2 and the base 1 and are evenly distributed along the ring shape, but the number and arrangement method are not limited to this. Preferably, the rotary snap - fit assembly includes a number of mutually - cooperating snap - fit protrusions 21 and snap - fit grooves 41. One of the centrifuge cup 2 and the base 1 is provided with snap - fit protrusions 21, and the other is provided with snap - fit grooves 41. In the first embodiment, the snap - fit protrusions 21 are provided at the bottom of the centrifuge cup 2, and the snap - fit grooves 41 are provided on the base 1. Preferably, a convex ring 22 is provided at the bottom of the centrifuge cup 2, and the snap - fit protrusions 21 are evenly arranged at the inner circumferential position of the convex ring 22.

[0050] The snap - fit groove 41 is in the shape of "┘", and each snap - fit groove 41 includes a circumferential limiting groove 412 and an axial guiding groove 411 that are in communication with each other. The circumferential limiting groove 412 extends circumferentially. When the centrifuge cup 2 is rotated forward, the snap - fit protrusion 21 at the bottom of the centrifuge cup 2 moves from the opening of the circumferential limiting groove 412 to the bottom of the circumferential limiting groove 412 until it abuts against the circumferential limiting groove 412, so that the circumferential limiting groove 412 can limit the centrifuge cup 2 from rotating forward continuously, that is, the circumferential limiting groove 412 can unidirectionally limit the rotation of the snap - fit protrusion 21. The axial guiding groove 411 extends axially, and the axial guiding groove 411 is perpendicularly connected to the circumferential limiting groove 412. Of course, the structure of the snap - fit groove 41 is not limited to this. Preferably, an interference fit can be formed between the snap - fit protrusion 21 and the circumferential limiting groove 412 (the axial thickness of the snap - fit protrusion 21 is slightly greater than the axial height of the circumferential limiting groove 412) to limit the two - way axial position movement of the centrifuge cup 2.

[0051] In addition, a centrifuge cup accommodation cavity 311 is provided on the base 1. When the centrifuge cup 2 and the base 1 are connected together as a whole, the circumferential side wall 312 of the centrifuge cup accommodation cavity 311 wraps the outer side of the cup body of the centrifuge cup 2, and this circumferential side wall 312 can play a role in radial limiting on the centrifuge cup 2 to further ensure the stability of the centrifuge cup 2 during rotation.

[0052] Specifically, when the centrifuge cup 2 is placed into the base 1, the fastening protrusion 21 at the bottom of the centrifuge cup 2 moves along the axial guiding groove 411 towards the base. When the centrifuge cup 2 enters the preset depth inside the base, the centrifuge cup 2 is rotated forward to a preset angle, and the rotary fastening assembly clamps the centrifuge cup 2 and the base 1 together, thereby enabling the rotary fastening assembly to restrict the circumferential and axial movements of the centrifuge cup 2 (i.e., simultaneously imposing position constraints on the horizontal and vertical directions of the centrifuge cup); at the same time, the circumferential side wall 312 of the centrifuge cup accommodating cavity 311 in the base 1 wraps around the centrifuge cup 2 to restrict the radial movement of the centrifuge cup, thereby restricting the centrifuge cup 2 in terms of circumferential, axial, and radial directions, keeping the centrifuge cup stable during operation, and thus ensuring the separation accuracy and cell viability. On the contrary, rotating the centrifuge cup 2 in the reverse direction to the preset angle and then pulling out the centrifuge cup 2 axially can achieve the disassembly and separation between the centrifuge cup 2 and the base 1.

[0053] Preferably, when the centrifuge cup 2 and the base 1 are connected to each other as a whole (i.e., after the centrifuge cup 2 is installed on the base 1), the inner bottom surface 313 of the centrifuge cup accommodating cavity 311 abuts against the centrifuge cup 2 (it can be that the bottom surface 313 and the bottom surface of the centrifuge cup form a "surface - surface" abutment, or several protrusions can be provided on the bottom surface 313 or / and the bottom of the centrifuge cup to form a form of "protrusion - surface" abutment or "protrusion - protrusion" abutment). At the same time, the fastening protrusion 21 abuts against the fastening groove 41. Specifically, the top surface of the fastening protrusion 21 abuts against the inner top surface of the axial guiding groove to form a fastening position mating surface 413. By the bottom surface 313 of the centrifuge cup accommodating cavity 311 abutting against the centrifuge cup 2 and the formation of the fastening position mating surface 413, a more reliable and stable constraint on the axial position of the centrifuge cup can be formed.

[0054] Furthermore, an axial mounting hole 42 is provided on the base 1. The output shaft (centrifugal shaft) of the centrifugal mechanism can be inserted into this axial mounting hole 42, and then the base 1 and the output shaft of the centrifugal mechanism are tightly connected through a fastener. The fastener can be a screw or a bolt, but its form is not limited to this. Specifically, a threaded hole is provided at the top of the output shaft of the centrifugal mechanism. When the output shaft of the centrifugal mechanism is inserted into the axial mounting hole 42 from the bottom of the base to the preset position (the preset position here refers to the maximum depth at which the output shaft can be inserted into the axial mounting hole 42), a screw is screwed in from the top of the axial mounting hole 42, so that the screw cooperates with the threaded hole at the top of the output shaft, thereby realizing the position locking between the base and the output shaft of the centrifugal mechanism.

[0055] Preferably, in order to better lock the positions between the base and the output shaft of the centrifugal mechanism (axial position and circumferential position), a limiting rib 421 can be provided in the axial mounting hole 42. A transitional fit is formed between this limiting rib 421 and the output shaft of the centrifugal mechanism. Combined with the locking of the fastener, a more reliable fastening connection between the base and the output shaft of the centrifugal mechanism is ensured.

[0056] Specifically, the circumferential side wall 312 of the centrifuge cup accommodating cavity 311 wraps the entire body of the centrifuge cup 2. At the same time, the circumferential side wall 312 of the centrifuge cup accommodating cavity 311 is made of a metal material with good heat conduction performance, such as aluminum, copper, iron, steel, etc. By wrapping the centrifuge cup 2 with this metal side wall with good heat conduction performance, the contact heat conduction between the metal side wall (circumferential side wall 312) and the centrifuge cup can be realized by controlling the temperature of the metal side wall. Compared with the existing air heat transfer method, this method can achieve fast, stable and uniform heat conduction, and thus can improve the uniformity of the centrifuge cup maintaining the target temperature. Moreover, when culturing cells, the centrifuge cup can also be prevented from fogging. Therefore, the method of wrapping the circumferential side wall 312 around the body of the centrifuge cup can not only realize reliable restraint of the radial position of the centrifuge cup, but also realize the function of controlling the temperature conduction of the centrifuge cup.

[0057] Furthermore, in order to avoid the formation of an arc convex angle when numerically controlling the inner right angle of the centrifuge cup accommodating cavity 311, which may cause the centrifuge cup 2 to not fit tightly against the bottom surface 313, a recessed groove can be formed at the connection between the circumferential side wall 312 and the bottom surface 313 of the centrifuge cup accommodating cavity 311. This recessed groove is preferably a rounded recessed groove 314.

[0058] Preferably, the base 1 includes a fixed seat 3 and a mounting seat 4. The centrifuge cup accommodating cavity 311 is provided on the fixed seat 3. The mounting seat 4 is coaxially connected to the fixed seat 3. The snap-in groove 41 is provided on the mounting seat 4. This mounting seat 4 is preferably cylindrical. The circumferential limiting groove 412 extends circumferentially on this mounting seat 4, and the axial guiding groove 411 extends axially along the mounting seat 4 and penetrates the height of the mounting seat 4.

[0059] Preferably, the fixed seat 4 and the mounting seat 3 are integrally formed. The outer contour of the fixed seat 4 is in an inverted convex shape. Its internal cavity includes the centrifuge cup accommodating cavity 311 and the mounting seat accommodating cavity 317. The mounting seat 3 is arranged in the mounting seat accommodating cavity 317. Preferably, the top surface height of the mounting seat 3 is flush with or lower than the bottom surface 313 of the centrifuge cup accommodating cavity 311.

[0060] Figure 7It is a schematic cross-sectional structure diagram of the centrifuge cup fixing device provided by the second specific embodiment of the present utility model. In the second specific embodiment, other structures are the same as those of the first specific embodiment, only the integral molding method of the fixing base 4 and the mounting base 3 is changed to split molding, that is, the fixing base 4 and the mounting base 3 are independent components, and the two are processed separately. At this time, the axial mounting hole 42 is composed of a locking hole 422 provided on the mounting base 3 and a through hole 423 provided on the fixing base 3, and the limiting rib 421 can be provided at the lower part inside the locking hole 422 of the mounting base 3. When the screw in the locking hole 422 is fixedly connected to the output shaft of the centrifugal mechanism, the fastening connection between the fixing base 4 and the mounting base 3 is also realized (this can adopt the traditional motor shaft connection method, such as restricting radial movement through a positioning pin or other cooperation, and then restricting axial movement by using the shaft end structure in cooperation with a threaded fastener).

[0061] Figure 8 It is a schematic cross-sectional structure diagram of the centrifuge cup fixing device provided by the third specific embodiment of the present utility model. In the third specific embodiment, other structures are the same as those of the first specific embodiment, only the height of the circumferential side wall 312 of the centrifuge cup accommodating cavity 311 is changed so that it only covers a part of the cup body height of the centrifuge cup 2. In short, the height of the circumferential side wall 312 covering the centrifuge cup body can be adjusted according to the actual situation.

[0062] Figure 9 It is a schematic cross-sectional structure diagram of the centrifuge cup fixing device provided by the fourth specific embodiment of the present utility model. In the fourth specific embodiment, other structures are the same as those of the first specific embodiment, only the shape of the concave groove at the connection between the circumferential side wall 312 and the bottom surface 313 of the centrifuge cup accommodating cavity 311 is changed to a notch shape, that is, the rounded concave groove 314 is replaced by a notch concave groove 315. Of course, the structure of the concave groove is not limited to the above two types.

[0063] Figure 10 It is a schematic cross-sectional structure diagram of the centrifuge cup fixing device provided by the fifth specific embodiment of the present utility model. In the fifth specific embodiment, other structures are the same as those of the first specific embodiment, only a plurality of perspective windows are opened at the bottom of the fixing base. Specifically, when the centrifuge cup is used for automated processing, such as cell culture or cell washing, it may be necessary to use a camera or other sensors to detect the internal situation of the centrifuge cup. Therefore, a plurality of perspective windows 316 can be provided on the base 1, and the number thereof can be 0 - 10, and the shape of the opening can be circular, square or other shapes, and the position of the opening can be any position on the bottom surface of the fixing base.

[0064] Figure 11It is a schematic structural diagram of the centrifuge cup fixing device provided by the sixth specific embodiment of the present utility model. In the sixth specific embodiment, other structures are the same as those of the first specific embodiment, except that buffer washers 318 are provided on the upper inner side of the circumferential side wall 312 of the centrifuge cup accommodating cavity 311 and / or on the bottom surface 313 of the centrifuge cup accommodating cavity 311. Specifically, since disposable centrifuge cups are mostly made of plastic and are prone to deformation when the centrifugal force is large, at this time, a circle of buffer washers 318 is added at the position closest to the top inside the side wall of the fixing base 3 (where the deformation of the centrifuge cup is the largest when the centrifugal force is large) and at the middle position of the bottom surface 313 of the centrifuge cup accommodating cavity 311, so that the centrifuge cup has a buffer space after encountering deformation or eccentricity during movement, reducing noise and at the same time reducing the impact of noise on cells. Preferably, the buffer washer can be a rubber washer or a silicone washer, and installation grooves can be provided at corresponding positions on the circumferential side wall 312 and the bottom surface 313, and the buffer washer is embedded and installed in this installation groove.

[0065] Figure 12 It is a schematic cross-sectional structure diagram of the centrifuge cup fixing device provided by the seventh specific embodiment of the present utility model. In the seventh specific embodiment, other structures are the same as those of the sixth specific embodiment, except that a continuous buffer washer 318 is replaced with a non-continuous multi-segment type. Specifically, multiple arc-shaped buffer washers 318 are evenly distributed in the circumferential direction, and the specific number is not limited.

[0066] The centrifuge cup fixing device provided by the present utility model has been introduced in detail above. Specific examples are used in this article to elaborate on the principle and implementation manner of the present utility model. The description of the above embodiments is only used to help understand the method and its core idea of the present utility model; at the same time, for those of ordinary skill in the art, according to the idea of the present utility model, there will be changes in the specific implementation manner and application scope. Therefore, the content of this specification should not be construed as a limitation to the present utility model.

Claims

1. A centrifugal cup fixing device, comprising a base, characterized in that: It also includes a rotation buckle assembly for connecting the centrifugal cup and the base. The rotation buckle assembly is used to clamp the centrifugal cup and the base into one after the centrifugal cup is rotated to a preset angle relative to the base.

2. A centrifugal cup fixing device according to claim 1, characterized in that: The rotating snap-fit ​​assembly includes a plurality of groups of snap-fit ​​protrusions and snap-fit ​​grooves that cooperate with each other. One of the centrifugal cup and the base is provided with a snap-fit ​​protrusion, and the other is provided with a snap-fit ​​groove. The snap-fit ​​groove includes a circumferential limit groove for unidirectionally limiting the rotation of the snap-fit ​​protrusion and an axial guide groove vertically connected to the circumferential limit groove and used to guide the snap-fit ​​protrusion into the circumferential limit groove.

3. A centrifugal cup fixing device according to claim 2, characterized in that: The base comprises a fixing seat and a mounting seat, a centrifugal cup accommodating cavity is provided in the fixing seat, the mounting seat is coaxially connected with the fixing seat, and the buckling groove or the buckling protrusion is arranged on the mounting seat.

4. A centrifugal cup fixing device according to claim 3, characterized in that: The fixing seat and the mounting seat are integrally formed or are independent components.

5. A centrifugal cup fixing device according to claim 3, characterized in that: The outer contour of the fixing seat is in an inverted convex shape, and a mounting seat accommodating cavity is provided inside the fixing seat, and the mounting seat is arranged in the mounting seat accommodating cavity.

6. A centrifugal cup fixing device according to claim 3, characterized in that: When the centrifugal cup and the base are connected to each other as one body, the circumferential side wall of the centrifugal cup accommodating cavity covers part or the entire centrifugal cup body, and the circumferential side wall of the centrifugal cup accommodating cavity is made of metal material with good thermal conductivity.

7. A centrifugal cup fixing device according to claim 3, characterized in that: A concave groove is formed at the connection between the circumferential side wall and the bottom surface of the centrifugal cup accommodating cavity.

8. A centrifugal cup fixing device according to claim 3, characterized in that: A buffer gasket is arranged on the inner upper part of the circumferential side wall of the centrifugal cup accommodating cavity and / or on the bottom surface of the centrifugal cup accommodating cavity.

9. A centrifugal cup fixing device according to any one of claims 1 to 8, characterized in that: An axial mounting hole is provided on the base, and the base is fastened to the output shaft of the centrifugal mechanism entering the axial mounting hole through a fastener; a limiting convex rib is provided in the axial mounting hole for forming a transition fit with the output shaft of the centrifugal mechanism.

10. A centrifugal cup fixing device according to any one of claims 1 to 8, characterized in that: A plurality of perspective windows are also arranged on the base.