PCR (Polymerase Chain Reaction) detection reagent freeze-dried bead subpackaging device
By designing a PCR detection reagent freeze-dried bead packer including anti-blocking structure and disassembly structure, the problem of existing disassembly inconvenient for multi-component packing and blocking of blanking ports is solved, and efficient freeze-dried bead packing is achieved.
Patent Information
- Application Number
- CN202421752631.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-24
- Publication Date
- 2025-06-24
- Estimated Expiration
- 2034-07-24
AI Technical Summary
The existing PCR detection reagent freeze-dried beads are not convenient for multi-component aliquots of freeze-dried beads, and freeze-dried beads are easily blocked when they are blanked, affecting the aliquot efficiency.
A packer including a storage bottle, a sealing cap, an anti-blocking structure, a piece of material separation box, a piece of material separation chamber, a piece of material separation structure and a piece of material separation pipe is designed. The anti-blocking structure prevents the lyophilized beads from accumulating and blocking the blanking ports, and the multi-component aggregation of the lyophilized beads is achieved through the aggregation structure.
It effectively prevents the blanking port blockage caused by the accumulation of freeze-dried beads, improves the aliquoting efficiency of freeze-dried beads, realizes multi-component aliquoting of freeze-dried beads, and improves work efficiency.
Smart Images
Figure CN223014942U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of freeze-dried beads of PCR detection reagents, and particularly relates to a dispenser for freeze-dried beads of PCR detection reagents. Background Art
[0002] The freeze-dried beads of PCR detection reagents are an innovative molecular biology product used to simplify and improve the efficiency and stability of PCR detection. The dispenser for freeze-dried beads of PCR detection reagents is a device specially designed for efficient and precise dispensing of freeze-dried beads of PCR reagents, aiming to improve production efficiency and ensure dispensing accuracy.
[0003] In the process of using the existing dispenser for freeze-dried beads of PCR detection reagents, it is not convenient to perform multi-component dispensing of freeze-dried beads, thus reducing the dispensing efficiency. In addition, the freeze-dried beads are likely to cause blockage of the material dropping port during the dropping process, making it inconvenient to dispense the freeze-dried beads. Summary of the Utility Model
[0004] The purpose of the utility model is to provide a dispenser for freeze-dried beads of PCR detection reagents to solve the defect that the existing dispenser for freeze-dried beads of PCR detection reagents is not convenient for multi-component dispensing of freeze-dried beads.
[0005] To solve the above technical problems, the utility model provides the following technical solution: A dispenser for freeze-dried beads of PCR detection reagents, comprising a storage bottle and a sealing cover;
[0006] The storage bottle includes a sealing cover, an anti-blocking structure, a material distribution box, a material distribution cavity, a dispensing structure, a dispensing tube and an observation window. The sealing cover is arranged at the top end of the storage bottle, and the anti-blocking structure is arranged inside the storage bottle;
[0007] The bottom end of the storage bottle is fixed with a material distribution box. The inside of the material distribution box is provided with a material distribution cavity, and the inside of the material distribution cavity is provided with a dispensing structure;
[0008] The two sides at the bottom end of the material distribution box are provided with dispensing tubes, and observation windows are arranged on one side of the storage bottle and the material distribution box respectively.
[0009] Preferably, the anti-blocking structure includes a rotating shaft, a spiral blade, a first bevel gear, a second bevel gear, a rotating rod, a rotating block and a material dropping port. The rotating shaft is arranged at the middle position inside the storage bottle. A spiral blade is fixed on the outer side of the rotating shaft. A first bevel gear is fixed at the top end of the rotating shaft. A second bevel gear is arranged on one side of the first bevel gear. A rotating rod is fixed at one end of the second bevel gear. A rotating block is fixed at one end of the rotating rod. The material dropping port is arranged at the bottom end inside the storage bottle.
[0010] Preferably, the first bevel gear is meshed with the second bevel gear, the first bevel gear and the second bevel gear are vertically distributed, and one end of the rotating rod penetrates through one side of the storage bottle and extends to the outside of the storage bottle and is fixedly connected to one end of the rotating block.
[0011] Preferably, the material dropping port is arranged in a funnel shape, and the bottom end of the material dropping port penetrates through the middle position of the top end of the material distribution box and extends into the interior of the material distribution cavity.
[0012] Preferably, the packaging structure includes a boss, a fixed frame, a movable rod, a spring, a moving plate, a pressing block, a baffle, a first through hole, a second through hole, a mounting plate, a third through hole, an annular magnet and a mounting hole. The boss is fixed to the top end inside the material distribution cavity. Fixed frames are fixed on both sides of the top end of the boss. A movable rod is arranged inside the fixed frame. A spring is arranged on the outer side of the movable rod. One end of the movable rod is fixed to a moving plate. The other end of the movable rod is fixed to a pressing block. A baffle is fixed to one side of the moving plate. A first through hole is arranged at the middle position inside the baffle. Second through holes are arranged on both sides inside the boss. A mounting plate is fixed to the inside of the material distribution cavity at the bottom end of the boss. Third through holes are arranged on both sides inside the mounting plate. An annular magnet is arranged on the outer side of the third through hole at the bottom end of the mounting plate. Mounting holes are arranged on both sides of the bottom end of the material distribution box.
[0013] Preferably, there are two groups of fixed frames, the fixed frames are symmetrically distributed at the top end of the boss, and one ends of the movable rods penetrate through both sides of the material distribution box and extend to the outside of the material distribution box and are fixedly connected to one ends of the pressing blocks.
[0014] Preferably, the movable rod and the fixed frame form a telescopic structure through the spring. The diameters of the first through hole, the second through hole and the third through hole are the same, and the second through hole and the third through hole correspond to each other one by one.
[0015] The advantages of the PCR detection reagent freeze-dried bead packaging device provided by the present utility model are as follows:
[0016] By providing an anti-blocking structure, the rotating block is rotated to drive the rotating rod, so that the second bevel gear drives the first bevel gear to rotate. By the rotation of the first bevel gear, the rotating shaft is driven to rotate the spiral blade. Furthermore, through the rotation of the spiral blade, the freeze-dried beads inside the storage bottle are conveyed into the interior of the material dropping port through the bolt, thereby preventing the blockage of the material dropping port caused by the accumulation of freeze-dried beads and facilitating the packaging of the freeze-dried beads.
[0017] By setting up a sub-packaging structure, two groups of sub-packaging tubes enter the interior of the material distribution chamber through the mounting holes respectively and are fixedly connected through annular magnetic blocks. When the freeze-dried beads fall into the interior of the first through-hole from the material dropping port, by pulling the pressing block on one side of the material distribution box, the movable rod drives the moving plate to move, causing the spring to be compressed and undergo elastic deformation. The movement of the moving plate drives the baffle, and then the baffle drives the first through-hole to move above the second through-hole, so that the freeze-dried beads fall from the first through-hole into the interior of the second through-hole and enter the interior of the sub-packaging tube through the third through-hole. Similarly, by pulling the pressing block on the other side of the material distribution box, the freeze-dried beads fall into the interior of the other group of sub-packaging tubes. By pulling the pressing blocks on both sides of the material distribution box to drive the baffle to move back and forth, the secondary sub-packaging of the freeze-dried beads is realized, thus improving the work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 is a three-dimensional structure diagram of the present utility model;
[0019] Figure 2 is a front cross-sectional structure diagram of the present utility model;
[0020] Figure 3 is of the present utility model Figure 2 magnified structure diagram at A in;
[0021] Figure 4 is a three-dimensional cross-sectional structure diagram of the present utility model;
[0022] Figure 5 is a three-dimensional structure diagram of the sub-packaging structure of the present utility model.
[0023] Explanation of the reference numerals in the drawings: 1. Storage bottle; 101. Sealing cap; 102. Anti-blocking structure; 1021. Rotating shaft; 1022. Spiral blade; 1023. First bevel gear; 1024. Second bevel gear; 1025. Rotating rod; 1026. Rotating block; 1027. Material dropping port; 103. Material distribution box; 104. Material distribution chamber; 105. Sub-packaging structure; 1051. Boss; 1052. Fixed frame; 1053. Movable rod; 1054. Spring; 1055. Moving plate; 1056. Pressing block; 1057. Baffle; 1058. First through-hole; 1059. Second through-hole; 10510. Mounting plate; 10511. Third through-hole; 10512. Annular magnetic block; 10513. Mounting hole; 106. Sub-packaging tube; 107. Observation window. DETAILED DESCRIPTION OF THE EMBODIMENTS
[0024] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.
[0025] Please refer to Figures 1-5 , the PCR detection reagent lyophilized bead dispenser provided by the present invention includes a storage bottle 1 and a sealing cap 101.
[0026] Refer to Figure 2 and Figure 4 As shown, the storage bottle 1 includes a sealing cap 101, an anti-blocking structure 102, a material distribution box 103, a material distribution cavity 104, a dispensing structure 105, a dispensing tube 106, and an observation window 107. The sealing cap 101 is provided at the top end of the storage bottle 1. An anti-blocking structure 102 is provided inside the storage bottle 1. The anti-blocking structure 102 includes a rotating shaft 1021, a spiral blade 1022, a first bevel gear 1023, a second bevel gear 1024, a rotating rod 1025, a rotating block 1026, and a material dropping port 1027. The rotating shaft 1021 is provided at the middle position inside the storage bottle 1. A spiral blade 1022 is fixed to the outer side of the rotating shaft 1021. A first bevel gear 1023 is fixed to the top end of the rotating shaft 1021. A second bevel gear 1024 is provided on one side of the first bevel gear 1023. A rotating rod 1025 is fixed to one end of the second bevel gear 1024. A rotating block 1026 is fixed to one end of the rotating rod 1025. A material dropping port 1027 is provided at the bottom end inside the storage bottle 1. The first bevel gear 1023 is meshed with the second bevel gear 1024. The first bevel gear 1023 and the second bevel gear 1024 are vertically distributed. One end of the rotating rod 1025 penetrates through one side of the storage bottle 1 and extends to the outside of the storage bottle 1 and is fixed to one end of the rotating block 1026. The material dropping port 1027 is arranged in a funnel shape. The bottom end of the storage bottle 1 is fixed with a material distribution box 103. A material distribution cavity 104 is provided inside the material distribution box 103. The bottom end of the material dropping port 1027 penetrates through the middle position of the top end of the material distribution box 103 and extends into the material distribution cavity 104.
[0027] By rotating the rotating block 1026 to drive the rotating rod 1025, the second bevel gear 1024 drives the first bevel gear 1023 to rotate. By the rotation of the first bevel gear 1023, the rotating shaft 1021 is driven to make the spiral blade 1022 rotate. Furthermore, through the rotation of the spiral blade 1022, the lyophilized beads inside the storage bottle 1 are conveyed into the material dropping port 1027 through the bolt, thereby preventing the blockage of the material dropping port 1027 caused by the accumulation of lyophilized beads and facilitating the dispensing of lyophilized beads.
[0028] Refer toFigures 1-5 As shown, a dispensing structure 105 is provided inside the material distribution cavity 104. The dispensing structure 105 includes a boss 1051, a fixed frame 1052, a movable rod 1053, a spring 1054, a moving plate 1055, a pressing block 1056, a baffle 1057, a first through hole 1058, a second through hole 1059, a mounting plate 10510, a third through hole 10511, an annular magnet 10512, and a mounting hole 10513. The boss 1051 is fixed to the top end inside the material distribution cavity 104. Fixed frames 1052 are fixed on both sides of the top end of the boss 1051. A movable rod 1053 is provided inside the fixed frame 1052. A spring 1054 is provided on the outer side of the movable rod 1053. One end of the movable rod 1053 is fixed with a moving plate 1055, and the other end of the movable rod 1053 is fixed with a pressing block 1056. A baffle 1057 is fixed on one side of the moving plate 1055. A first through hole 1058 is provided at the middle position inside the baffle 1057. Second through holes 1059 are provided on both sides inside the boss 1051. A mounting plate 10510 is fixed inside the material distribution cavity 104 at the bottom end of the boss 1051. Third through holes 10511 are provided on both sides inside the mounting plate 10510. An annular magnet 10512 is provided on the outer side of the third through hole 10511 at the bottom end of the mounting plate 10510. Mounting holes 10513 are provided on both sides at the bottom end of the material distribution box 103. There are two groups of fixed frames 1052, and the fixed frames 1052 are symmetrically distributed at the top end of the boss 1051. One end of the movable rod 1053 respectively penetrates through both sides of the material distribution box 103 and extends to the outside of the material distribution box 103 and is fixedly connected to one end of the pressing block 1056. The movable rod 1053 and the fixed frame 1052 form a telescopic structure through the spring 1054. The diameters of the first through hole 1058, the second through hole 1059, and the third through hole 10511 are the same. The second through holes 1059 correspond to the third through holes 10511 one by one. Dispensing pipes 106 are provided on both sides at the bottom end of the material distribution box 103. Observation windows 107 are provided on one side of both the storage bottle 1 and the material distribution box 103.
[0029] Two groups of dispensing tubes 106 respectively enter the inside of the material distribution cavity 104 through the mounting holes 10513 and are fixedly connected respectively through the annular magnetic blocks 10512. When the freeze-dried beads fall into the inside of the first through hole 1058 from the material dropping port 1027, by pulling the pressing block 1056 on one side of the material distribution box 103, the movable rod 1053 drives the moving plate 1055 to move, so that the spring 1054 is compressed to generate elastic deformation. By the movement of the moving plate 1055, the baffle 1057 is driven, and then the baffle 1057 drives the first through hole 1058 to move above the second through hole 1059, so that the freeze-dried beads fall from the first through hole 1058 into the inside of the second through hole 1059 and enter the inside of the dispensing tube 106 through the third through hole 10511. Similarly, by pulling the pressing block 1056 on the other side of the material distribution box 103, the freeze-dried beads fall into the inside of the other group of dispensing tubes 106. By pulling the pressing blocks 1056 on both sides of the material distribution box 103, the baffle 1057 is driven to move reciprocally, thereby realizing the secondary dispensing of the freeze-dried beads, and thus improving the working efficiency.
[0030] Although the present utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.
Claims
1. A PCR detection reagent freeze-dried bead dispenser, comprising a storage bottle (1) and a sealing cap (101); Features: The material storage bottle (1) comprises a sealing cover (101), an anti-blocking structure (102), a material distribution box (103), a material distribution chamber (104), a dispensing structure (105), a dispensing tube (106) and an observation window (107); the sealing cover (101) is arranged on the top of the material storage bottle (1), and the anti-blocking structure (102) is arranged inside the material storage bottle (1); A material distribution box (103) is fixed at the bottom end of the material storage bottle (1), a material distribution cavity (104) is provided inside the material distribution box (103), and a dispensing structure (105) is provided inside the material distribution cavity (104); Dispensing tubes (106) are provided on both sides of the bottom of the dispensing box (103), and observation windows (107) are provided on one side of the storage bottle (1) and the dispensing box (103).
2. The PCR detection reagent freeze-dried bead dispenser according to claim 1, characterized in that: The anti-blocking structure (102) comprises a rotating shaft (1021), a spiral blade (1022), a first bevel gear (1023), a second bevel gear (1024), a rotating rod (1025), a rotating block (1026) and a material drop opening (1027); the rotating shaft (1021) is arranged at a middle position inside the material storage bottle (1); the spiral blade (1022) is fixed to the outside of the rotating shaft (1021); the first bevel gear (1023) is fixed to the top of the rotating shaft (1021); the second bevel gear (1024) is arranged on one side of the first bevel gear (1023); the rotating rod (1025) is fixed to one end of the second bevel gear (1024); the rotating block (1026) is fixed to one end of the rotating rod (1025); and the material drop opening (1027) is arranged at the bottom end inside the material storage bottle (1).
3. The PCR detection reagent freeze-dried bead dispenser according to claim 2, characterized in that: The first bevel gear (1023) is meshedly connected with the second bevel gear (1024); the first bevel gear (1023) and the second bevel gear (1024) are vertically distributed; one end of the rotating rod (1025) passes through one side of the storage bottle (1), extends to the outside of the storage bottle (1), and is fixedly connected to one end of the rotating block (1026).
4. The PCR detection reagent freeze-dried bead dispenser according to claim 2, characterized in that: The material drop opening (1027) is arranged in a funnel shape, and the bottom end of the material drop opening (1027) passes through the middle position of the top end of the material distribution box (103) and extends to the inside of the material distribution cavity (104).
5. The PCR detection reagent freeze-dried bead dispenser according to claim 1, characterized in that: The dispensing structure (105) comprises a boss (1051), a fixed frame (1052), a movable rod (1053), a spring (1054), a movable plate (1055), a pressing block (1056), a baffle (1057), a first through hole (1058), a second through hole (1059), a mounting plate (10510), a third through hole (10511), an annular magnetic block (10512) and a mounting hole (10513); the boss (1051) is fixed to the top of the dispensing cavity (104); fixed frames (1052) are fixed on both sides of the top of the boss (1051); a movable rod (1053) is arranged inside the fixed frame (1052); a spring (1054) is arranged on the outside of the movable rod (1053); one side of the movable rod (1053) is provided with a spring (1054); and a portion of the movable rod (1053) is provided with a spring (1054). A movable plate (1055) is fixed at one end of the movable rod (1053), a pressing block (1056) is fixed at the other end of the movable rod (1053), a baffle (1057) is fixed on one side of the movable plate (1055), a first through hole (1058) is provided at a middle position inside the baffle (1057), second through holes (1059) are provided on both sides inside the boss (1051), a mounting plate (10510) is fixed inside the material dispensing cavity (104) at the bottom end of the boss (1051), third through holes (10511) are provided on both sides inside the mounting plate (10510), an annular magnetic block (10512) is provided on the outer side of the third through hole (10511) at the bottom end of the mounting plate (10510), and mounting holes (10513) are provided on both sides of the bottom end of the material dispensing box (103).
6. The PCR detection reagent freeze-dried bead dispenser according to claim 5, characterized in that: Two groups of the fixing frames (1052) are provided. The fixing frames (1052) are symmetrically distributed on the top of the boss (1051). One end of the movable rod (1053) passes through both sides of the material distribution box (103) and extends to the outside of the material distribution box (103) and is fixedly connected to one end of the pressing block (1056).
7. The PCR detection reagent freeze-dried bead dispenser according to claim 5, characterized in that: The movable rod (1053) and the fixed frame (1052) form a telescopic structure via a spring (1054); the first through hole (1058), the second through hole (1059) and the third through hole (10511) have the same diameter; the second through hole (1059) corresponds to the third through hole (10511) one by one.