Storable side-position bubbling rod

Abstract

The utility model relates to the technical field of cell culture, and discloses a storable side position bubbling rod, which comprises a T-shaped silica gel joint, two big bubble distribution pipes, a silica gel short pipe, an adapter hose and a plug, the two big bubble distribution pipes are distributed on the two sides of the T-shaped silica gel joint and are connected with the joints on the two sides of the T-shaped silica gel joint, the joint at the bottom of the T-shaped silica gel joint is connected with the silica gel short pipe, and the adapter hose is connected with the plug. The adapter hose is connected to the bottom of the silica gel short tube. After the silica gel connector is used in the T-shaped structure of the device, the T-shaped structure can be folded in half, the device has remarkable advantages in the packaging and transporting process of the reaction bag, the occupied space is effectively reduced, the transporting efficiency is improved, and compared with other structures, the risk of damage is also reduced in the transporting process through the T-shaped structure. The T-shaped structure of the device is applied to the field of cell culture, the surface roughness can be increased by optimizing the surface treatment technology, cell attachment is more stable, and the device has important significance on stability and reliability of cell culture.

Description

Technical Field

[0001] The utility model relates to the field of cell culture, and particularly to a retractable side-position bubbling rod. Background Art

[0002] In some large-scale high-density cell cultures in biopharmaceutical enterprises, the accumulation of carbon dioxide will become a prominent problem. Since the partial pressure of carbon dioxide (pCO2) is proportional to the pressure, the higher the liquid level, the greater the partial pressure of carbon dioxide at the bottom. Too high (>80 mmHg) or too low (<30 mmHg) pCO2 is not conducive to cell growth, metabolism, protein production, and quality control. Research shows that increasing the deep ventilation volume or using a large-bubble distributor can significantly reduce CO2. The prior art achieves the purpose of reducing pCO2 by adding a 2-mm large-bubble distributor. The existing T-shaped reaction bag set may occupy a large space during packing and transportation, increasing transportation costs and having poor stability when stacked.

[0003] The patent application with the publication number CN204752745U discloses an air pipe for an animal cell culture bioreactor. The air pipe includes a gas distribution pipe and an air pipe in pipeline connection with the gas distribution pipe. The gas distribution pipe is an elastic hose, and elastic closing holes that are opened under pressure are arranged on the surface of the gas distribution pipe.

[0004] The existing technical device has poor use effect, and the equipment transportation occupies a large space and has high transportation costs.

[0005] Therefore, a new technical solution is needed to solve the above technical problems. Summary of the Utility Model

[0006] The purpose of the utility model is to provide a retractable side-position bubbling rod. After using a silicone joint for the T-shaped structure, the T-shaped structure can be folded in half, which has significant advantages during the packing and transportation of the reaction bag, effectively reducing the occupied space, improving transportation efficiency, and reducing the risk of damage during transportation compared with other structures.

[0007] The technical solution adopted by the utility model is as follows:

[0008] A retractable side-position bubbling rod includes a T-shaped silicone joint, large-bubble distribution pipes, silicone short pipes, adapter hoses, and plugs. Two large-bubble distribution pipes are arranged on both sides of the T-shaped silicone joint and are connected to the joints on both sides of the T-shaped silicone joint. The joint at the bottom of the T-shaped silicone joint is connected to the silicone short pipe, and the adapter hose is connected to the bottom of the silicone short pipe.

[0009] By adopting the above structure, the improvement of cell culture shedding by the device is achieved. The T-shaped structure can also increase the surface roughness by optimizing the surface treatment technology to enhance the adhesion between the silicone tube and the T-shaped silicone joint.

[0010] Preferably, the upward side of the large bubble distribution tube is evenly distributed with through holes, and the end of the large bubble distribution tube close to the T-shaped silicone joint is surface-treated to increase the surface roughness.

[0011] By adopting the above structure, the connection stability between the large bubble distribution tube and the T-shaped silicone joint is increased, and shedding is avoided.

[0012] Preferably, the T-shaped silicone joint is a T-shaped three-way joint, and the two side joints of the T-shaped silicone joint and the end of the large bubble distribution tube are bonded with glue.

[0013] By adopting the above structure, the connection between the large bubble distribution tube and the T-shaped silicone joint is more firm, and shedding during transportation is avoided.

[0014] Preferably, the T-shaped silicone joint can be folded in half, and the large bubble distribution tubes connected on both sides are overlapped as much as possible.

[0015] By adopting the above structure, the device is improved in terms of packing and transportation, reducing space occupation, improving transportation efficiency, and reducing the risk of breakage during transportation.

[0016] Preferably, a plug is arranged inside the outer end of the large bubble distribution tube to block the outer pipe orifice of the large bubble distribution tube.

[0017] By adopting the above structure, setting the plug can prevent the solution from flowing back.

[0018] Preferably, the top of the short silicone tube is sleeved into the bottom joint of the T-shaped silicone joint, and the bottom is sleeved into the top interface of the lower adapter hose.

[0019] By adopting the above structure, the short silicone tube is provided to connect the T-shaped silicone joint and the adapter hose.

[0020] Preferably, the bottom of the short silicone tube is sleeved on the disc joint, and a pipe connector is provided at the bottom of the disc joint.

[0021] By adopting the above structure, the disc joint facilitates the device to connect to other pipes.

[0022] Compared with the prior art, the present utility model has the following beneficial effects:

[0023] 1. After using the silicone joint for the T-shaped device of the present utility model, the T-shaped shape can be folded in half, which has significant advantages in the packing and transportation of the reaction bag, effectively reducing space occupation, improving transportation efficiency, and reducing the risk of breakage during transportation compared with others.

[0024] 2. The T-shaped structure of the device of the present utility model is applied to the field of cell culture. By optimizing the surface treatment technology, the surface roughness can be increased, strengthening the connection between the T-shaped silicone tube and the silicone tube and avoiding breakage.

[0025] 3. The T-shaped structure of the device of the present utility model occupies a small area, making it easy to cooperate with other shapes. This not only improves the space utilization rate of the laboratory or production line but also increases the convenience of operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 is the assembled finished product drawing of the present utility model;

[0027] Figure 2 is the structural schematic diagram of the present utility model;

[0028] Figure 3 is the connection schematic diagram of the T-shaped silicone joint and the large bubble distribution tube of the present utility model;

[0029] Figure 4 is the connection schematic diagram of the transfer hose and the disc joint of the present utility model.

[0030] Wherein: 1. T-shaped silicone joint; 2. Large bubble distribution tube; 3. Plug; 4. Silicone short tube; 5. Transfer hose; 6. Disc joint; 7. Through hole. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0031] As Figures 1-4 shown, a retractable side-position bubbling rod includes a T-shaped silicone joint 1, a large bubble distribution tube 2, a silicone short tube 4, a transfer hose 5, and a plug 3. Two large bubble distribution tubes 2 are provided and are distributed on both sides of the T-shaped silicone joint 1 and are connected to the joints on both sides of the T-shaped silicone joint 1. The bottom joint of the T-shaped silicone joint 1 is connected to the silicone short tube 4, and the transfer hose 5 is connected to the bottom of the silicone short tube 4. Through holes 7 are evenly distributed on the upward side of the large bubble distribution tube 2, and the end of the large bubble distribution tube 2 close to the T-shaped silicone joint 1 is subjected to plasma treatment to increase the surface roughness.

[0032] The T-shaped silicone joint 1 is a T-shaped three-way joint. The joints on both sides of the T-shaped silicone joint 1 and the ends of the large bubble distribution tube 2 are bonded with glue. The T-shaped silicone joint 1 can be folded in half, and the large bubble distribution tubes 2 connected on both sides can overlap. A plug 3 is arranged inside the outer end of the large bubble distribution tube 2 to block the outer pipe orifice of the large bubble distribution tube 2.

[0033] The top of the silicone short tube 4 is sleeved into the bottom joint of the T-shaped silicone joint 1, and the bottom is sleeved into the top interface of the lower transfer hose 5. The bottom of the silicone short tube 4 is sleeved on the disc joint 6, and a pipe connector is provided at the bottom of the disc joint 6.

[0034] When this device is in use, first place the large bubble distribution tube 2 against the end of the T-shaped silicone joint 1 and perform plasma treatment to increase the surface roughness and stability to avoid detachment. Then, insert the large bubble distribution tube 2 into the T-shaped silicone joint 1 and bond it using the glue process. Insert the plug 3 into the tail of the large bubble distribution tube 2, insert the short silicone tube 4 into the T-shaped silicone joint 1, and then connect the transfer hose 5 to the short silicone tube 4 and the disc joint 6. The device can then be put into use. The T-shaped large bubble distributor of this device can increase the deep ventilation volume. Increasing the deep ventilation volume or using the large bubble distributor can significantly reduce CO2, and can also save the space occupancy rate, improve transportation, and reduce the risk of damage during transportation.

[0035] The embodiments described above are only descriptions of the preferred embodiments of the present invention and do not limit the scope of the present invention. Without departing from the design spirit of the present invention, various deformations and improvements made by those skilled in the art to the technical solutions of the present invention should be included within the protection scope determined by the claims of the present invention.

Claims

1. A retractable side bubbling rod, comprising a T-shaped silicone joint, a large bubble distribution tube, a silicone short tube, a transfer hose, and a plug, characterized in that: The large bubble distribution pipes are provided with two, distributed on both sides of the T-shaped silicone joint, connected to the joints on both sides of the T-shaped silicone joint, the joint at the bottom of the T-shaped silicone joint is connected to the silicone short tube, and the adapter hose is connected to the bottom of the silicone short tube.

2. A retractable side bubbling rod according to claim 1, characterized in that: The large-bubble distribution pipe has through holes evenly distributed upward, and the end of the large-bubble distribution pipe close to the T-shaped silicone joint is surface treated to increase the surface roughness.

3. The retractable side bubbling rod according to claim 1, characterized in that: The T-shaped silicone joint is a T-shaped three-way joint, and the joints on both sides of the T-shaped silicone joint are bonded to the ends of the large bubble distribution pipe by glue.

4. The retractable side bubbling rod according to claim 3, characterized in that: The T-shaped silicone joint can be folded in half, and the large bubble distribution tubes connected on both sides can be overlapped.

5. The retractable side bubbling rod according to claim 1, characterized in that: A plug is arranged inside the outer end of the large bubble distribution pipe to block the outer pipe opening of the large bubble distribution pipe.

6. The retractable side bubbling rod according to claim 1, characterized in that: The top of the short silicone tube is inserted into the bottom joint of the T-shaped silicone joint, and the bottom is inserted into the top interface of the lower transfer hose.

7. The retractable side bubbling rod according to claim 1, characterized in that: The bottom of the short silicone tube is sleeved on the disc joint, and a pipeline connector is arranged at the bottom of the disc joint.

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