Plasma lipid turbidity removing device

Abstract

The utility model belongs to the technical field of blood separation, and particularly relates to a plasma lipid turbidity removing device. The device comprises a vertically-arranged shell, a centrifugal tube is vertically arranged in the shell, a driving part used for driving the centrifugal tube to rotate is installed at the bottom of the shell, a liquid inlet tube vertically penetrates through the top of the centrifugal tube, a first liquid outlet tube vertically penetrates through the bottom of the centrifugal tube, and a first collecting box is arranged on the right side of the shell; the first collecting box is communicated with the liquid inlet pipe through a first connecting pipe, the bottom of the first collecting box is connected with a second collecting box through a second connecting pipe, a filtering assembly is arranged on the second connecting pipe, a second liquid outlet pipe penetrates through the bottom of the second collecting box, and negative pressure assemblies are arranged on the first collecting box and the second collecting box. According to the utility model, the centrifugal tube is driven by the driving piece to rotate, blood is centrifugally layered through centrifugal force generated by rotation, large-particle fat in plasma is removed under the action of the filtering assembly, the filtered plasma is detected, and the accuracy of a detection result is improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of blood separation, and particularly relates to a plasma lipid turbidity removal device. Background Art

[0002] Blood is one of the most important substances in the human body. It is responsible for transporting oxygen, nutrients, and waste. Blood tests are an important means to understand the health status of the human body by detecting blood samples. It involves quantitative or qualitative analysis of various components and biochemical indicators in the blood, so as to help doctors evaluate the physiological state of patients, diagnose diseases, and monitor the treatment effect. When examining blood, a centrifuge is generally used to centrifuge blood samples. The centrifugal force generated by rotation separates blood components with different densities. Red blood cells with a higher density will settle at the bottom of the test tube, while plasma with a lower density will float on the upper layer.

[0003] When examining the separated plasma, for patients with high blood lipids, their plasma contains a considerable amount of fat particles after centrifugation, which will cause blood turbidity. These fat particles will affect the test results of the plasma, and the fat particles need to be removed before the examination. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a plasma lipid turbidity removal device, which has a simple structure, filters large particle fats in the plasma, and improves the accuracy of test results.

[0005] The plasma lipid turbidity removal device includes a vertically arranged housing. A centrifuge tube is vertically arranged inside the housing. A driving member for driving the centrifuge tube to rotate is installed at the bottom of the housing. A liquid inlet pipe is vertically penetrated through the top of the centrifuge tube, and a first liquid outlet pipe is vertically penetrated through the bottom of the centrifuge tube. A first collection box is arranged on the right side of the housing. The first collection box is communicated with the liquid inlet pipe through a first connecting pipe. The bottom of the first collection box is connected with a second collection box through a second connecting pipe. A filtering component for removing fat particles in the plasma is arranged on the second connecting pipe. A second liquid outlet pipe is penetrated through the bottom of the second collection box. A negative pressure component for providing negative pressure is arranged on the first collection box and the second collection box.

[0006] Further, the filtering component includes a filter adsorber. The filter adsorber is communicated with the first collection box through the second connecting pipe, and the filter adsorber is communicated with the second collection box through the second connecting pipe.

[0007] Further, the negative pressure component includes a negative pressure pipe. The left end of the negative pressure pipe is connected to the first collection box, the right end of the negative pressure pipe is connected with a negative pressure device, and a third connecting pipe is installed between the second collection box and the negative pressure pipe.

[0008] Further, a pipe clamp is installed on the negative pressure pipe between the first collection box and the third connecting pipe, and a third connecting pipe is installed on the third connecting pipe.

[0009] Further, a end cover is installed at the upper end of the liquid inlet pipe.

[0010] Further, the first collection box is made of a transparent material.

[0011] Further, scale lines are provided on the side wall of the first collection box.

[0012] Compared with the prior art, the utility model has the following beneficial effects:

[0013] In the utility model, the centrifuge tube is driven to rotate by a driving member, and the blood is centrifugally stratified by the centrifugal force generated by the rotation. The upper plasma is collected into the first collection box under the action of the negative pressure assembly and the pipeline, and under the action of the filtering assembly, large particle fats in the plasma are removed, and the filtered plasma is detected, thereby improving the accuracy of the detection result. Description of the Drawings

[0014] Figure 1 is a structural schematic diagram of the utility model;

[0015] Names of each component in the figure: 1. Housing; 2. Centrifuge tube; 3. Liquid inlet pipe; 4. End cover; 5. First connecting pipe; 6. First collection box; 7. Pipe clamp; 8. Negative pressure pipe; 9. Third connecting pipe; 10. Filter adsorber; 11. Second connecting pipe; 12. Second collection box; 13. Second liquid outlet pipe; 14. Scale line; 15. First liquid outlet pipe; 16. Driving member. Detailed Embodiments

[0016] The following further illustrates the utility model through specific embodiments with reference to the drawings, but the utility model is not limited thereto. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included within the protection scope of the present invention.

[0017] Embodiment 1

[0018] A plasma lipid turbidity removal device described in this embodiment, as Figure 1 shown, includes a vertically arranged housing 1 made of metal;

[0019] A centrifuge tube 2 is vertically arranged in the housing 1. A through groove communicating up and down is opened at the top of the housing 1. The centrifuge tube 2 is vertically fixed in the through groove and is made of glass;

[0020] A driving member 16 for driving the centrifuge tube 2 to rotate is installed at the bottom of the housing 1. The driving member 16 is a prior art, generally a motor or a motor, which drives the centrifuge tube 2 to rotate through the rotation of the motor. It is also possible to use an HDS928 blood component separator to drive the centrifuge tube 2 to rotate, and separate blood components with different densities by the centrifugal force generated by the rotation, which is beneficial to subsequent blood tests;

[0021] A liquid inlet pipe 3 is vertically installed through the top of the centrifuge tube 2. A through hole communicating up and down is opened at the top of the centrifuge tube 2. The liquid inlet pipe 3 is vertically and independently installed in the through hole, and the liquid inlet pipe 3 slides up and down along the depth direction of the through hole. When the centrifuge tube 2 is centrifuged, the liquid inlet pipe 3 is taken out to prevent the liquid inlet pipe 3 from affecting the separation of the blood in the centrifuge tube 2;

[0022] A first liquid outlet pipe 15 is vertically installed through the bottom of the centrifuge tube 2. A through hole communicating up and down is opened at the bottom of the centrifuge tube 2. The first liquid outlet pipe 15 is vertically fixed in the through hole. After the blood is centrifuged, the blood cells in the lower half are taken out of the centrifuge tube 2 through the first liquid outlet pipe 15 for subsequent detection. A control valve is installed on the first liquid outlet pipe 15 to control the opening and closing of the first liquid outlet pipe 15 to prevent blood from entering the first liquid outlet pipe 15 during the centrifugation process;

[0023] A first collection box 6 is arranged on the right side of the housing 1. The first collection box 6 is used to collect the upper plasma after centrifugation. The first collection box 6 is made of plastic material;

[0024] The first collection box 6 is communicated with the liquid inlet pipe 3 through a first connecting pipe 5. One end of the first connecting pipe 5 is connected to the liquid inlet of the first collection box 6, and the other end is installed on the liquid inlet pipe 3. The upper plasma after centrifugation is collected into the first collection box 6 through the liquid inlet pipe 3 and the first connecting pipe 5;

[0025] The bottom of the first collection box 6 is connected to a second collection box 12 through a second connecting pipe 11. The upper end of the second connecting pipe 11 is connected to the liquid outlet of the first collection box 6, and the lower end is connected to the liquid inlet of the second collection box 12. The plasma in the first collection box 6 flows into the second collection box 12 through the second connecting pipe 11;

[0026] A filter adsorber 10 is arranged between the first collection box 6 and the second collection box 12. The filter adsorber 10 is composed of a cellulose material and an ultrafiltration membrane. The cellulose material can effectively adsorb lipids. Combining with the selective permeability of the ultrafiltration membrane, it allows small molecule substances to pass through and blocks large molecule fat particles from passing through, thereby removing large particle fats in the plasma. The filter adsorber 10 is communicated with the first collection box 6 through a second connecting pipe 11. The upper end of the upper second connecting pipe 11 is connected to the liquid outlet of the first collection box 6, and the lower end is connected to the liquid inlet of the filter adsorber 10. The plasma in the first collection box 6 flows into the filter adsorber 10 through the upper second connecting pipe 11 for filtering the plasma. The filter adsorber 10 is communicated with the second collection box 12 through the second connecting pipe 11. The upper end of the lower second connecting pipe 11 is connected to the liquid outlet of the filter adsorber 10, and the lower end is connected to the liquid inlet of the second collection box 12. The filtered plasma is collected into the second collection box 12 through the lower second connecting pipe 11. The whole paragraph constitutes a filtering component for removing fat particles in the plasma. When the filtering component is in use, the plasma in the first collection box 6 flows into the filter adsorber 10 through the upper second connecting pipe 11, the large particle fats in the plasma are filtered by the filter adsorber 10, and the filtered plasma is collected into the second collection box 12 through the lower second connecting pipe 11, improving the accuracy of plasma detection. Of course, in the filtering component, the filter adsorber 10 can also adopt the prior art, such as the "filter adsorber" in the patent application No. "CN201420600517.X" and the patent name "A therapeutic plasma treatment device", to remove the fat particles in the plasma through the filter adsorber.

[0027] A second liquid outlet pipe 13 is penetrated through the bottom of the second collection box 12. The upper end of the second liquid outlet pipe 13 is connected to the liquid outlet of the second collection box 12. The filtered plasma is taken out of the second collection box 12 through the second liquid outlet pipe 13. The liquid inlet pipe 3, the first connecting pipe 5, the second connecting pipe 11 and the second liquid outlet pipe 13 all adopt common intravenous infusion tubes.

[0028] A negative pressure pipe 8 is connected to the first collection box 6. The right end of the negative pressure pipe 8 is connected to a negative pressure device. A through hole is opened at the top end of the side wall of the first collection box 6. The left end of the negative pressure pipe 8 is penetrated through the through hole. The right end of the negative pressure pipe 8 is connected to an external negative pressure device, generally a negative pressure aspirator. The right end of the negative pressure pipe 8 is connected to the negative pressure aspirator, and the negative pressure is provided by the negative pressure aspirator to drive the blood flow in the pipeline. A third connecting pipe 9 is installed between the second collection box 12 and the negative pressure pipe 8. A through hole is opened on the side wall of the second collection box 12. One end of the third connecting pipe 9 is penetrated through the through hole, and the other end of the third connecting pipe 9 is connected to the negative pressure pipe 8. The whole paragraph constitutes a negative pressure component for providing negative pressure.

[0029] When this embodiment is in use, a blood sample is input into the centrifuge tube 2 through the liquid inlet tube 3. The liquid inlet tube 3 is removed from the centrifuge tube 2, and the centrifuge tube 2 is driven to rotate by the driving member 16. After the blood is centrifuged and stratified, the blood cells in the lower layer flow out of the centrifuge tube 2 through the first liquid outlet tube 15. Under the action of the negative pressure assembly, the upper-layer plasma is collected into the first collection box 6 through the liquid inlet tube 3 and the first connecting tube 5. After the large-particle fat in the plasma is filtered by the filtering assembly, it is collected into the second collection box 12 and discharged from the second collection box 12 through the second liquid outlet tube 13, and the filtered plasma is detected to improve the accuracy of the detection result.

[0030] Embodiment 2

[0031] This embodiment will further illustrate the technology. As Figure 1 shown, a pipe clamp 7 is installed on the negative pressure pipe 8 between the first collection box 6 and the third connecting pipe 9. A third connecting pipe 9 is installed on the third connecting pipe 9, and a pipe clamp 7 is also installed on the upper second connecting pipe 11. The opening and closing of each pipeline are controlled by the pipe clamp 7 to control the blood flow in the pipeline. The pipe clamp 7 is made of plastic.

[0032] A end cap 4 is installed at the upper end of the liquid inlet tube 3. The end cap 4 is used to control the opening and closing of the upper end of the liquid inlet tube 3. End caps 4 are installed at the lower end of the first liquid outlet tube 15, the lower end of the second liquid outlet tube 13, and the right end of the negative pressure pipe 8.

[0033] Embodiment 3

[0034] This embodiment will further illustrate the technology. As Figure 1 shown, the first collection box 6 is made of a transparent material. The first collection box 6 is made of transparent plastic. The transparent first collection box 6 can directly show the volume of the plasma in the first collection box 6, which is convenient for medical staff to use. The second collection box 12 is made of the same material as the first collection box 6.

[0035] Scale lines 14 are provided on the side wall of the first collection box 6. The volume of the plasma is visually quantified through the scale lines 14, which is convenient for medical staff to use. Scale lines 14 are also provided on the second collection box 12.

Claims

1. A plasma lipid turbidity removal device, comprising a vertically arranged housing (1), a centrifuge tube (2) vertically arranged in the housing (1), a driving member (16) for driving the centrifuge tube (2) to rotate is installed at the bottom of the housing (1), a liquid inlet pipe (3) is vertically installed at the top of the centrifuge tube (2), and a first liquid outlet pipe (15) is vertically installed at the bottom of the centrifuge tube (2), characterized in that: A first collecting box (6) is arranged on the right side of the housing (1); the first collecting box (6) is connected to the liquid inlet pipe (3) via a first connecting pipe (5); the bottom of the first collecting box (6) is connected to the second collecting box (12) via a second connecting pipe (11); a filtering component for removing fat particles in plasma is arranged on the second connecting pipe (11); a second liquid outlet pipe (13) is passed through the bottom of the second collecting box (12); and negative pressure components for providing negative pressure are arranged on the first collecting box (6) and the second collecting box (12).

2. The plasma lipid purging device according to claim 1, characterized in that: The filter assembly comprises a filter adsorber (10), the filter adsorber (10) and the first collection box (6) are connected via a second connecting pipe (11), and the filter adsorber (10) and the second collection box (12) are connected via a second connecting pipe (11).

3. The plasma lipid purging device according to claim 1 or 2, characterized in that: The negative pressure assembly comprises a negative pressure tube (8), the left end of the negative pressure tube (8) is connected to the first collecting box (6), the right end of the negative pressure tube (8) is connected to a negative pressure device, and a third connecting tube (9) is installed between the second collecting box (12) and the negative pressure tube (8).

4. The plasma lipid turbidity removal device according to claim 3, characterized in that: A tube clamp (7) is installed on the negative pressure tube (8) between the first collecting box (6) and the third connecting tube (9), and a third connecting tube (9) is installed on the third connecting tube (9).

5. The plasma lipid purging device according to claim 1, characterized in that: An end cover (4) is installed at the upper end of the liquid inlet pipe (3).

6. The plasma lipid purging device according to claim 1, characterized in that: The first collecting box (6) is made of a transparent material.

7. The plasma lipid purging device according to claim 6, characterized in that: A scale mark (14) is provided on the side wall of the first collecting box (6).

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