Solid-phase extraction column filler pressing machine
By designing a solid-phase extraction column packing press, the combination of processing table, mold, cavity column, pressing column and downcompression mechanism is solved, and the problem of cushioning of filler in the prior art is complicated and difficult to ensure uniformity, achieving efficient and simple packing pressing, improving the uniformity of column chromatography effect and the reliability of experimental results.
Patent Information
- Application Number
- CN202422194503.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-09
- Publication Date
- 2025-06-27
- Estimated Expiration
- 2034-09-09
AI Technical Summary
During the preparation process of existing solid-phase extraction columns, the pressing operation of the filler is cumbersome and difficult to ensure uniformity, resulting in unsatisfactory column chromatography, which affects the reproducibility and accuracy of experimental results.
A solid-phase extraction column packing press is designed, including a processing table, mold, cavity column, pressing column and downcompression mechanism. By setting machine parameters, one pressing or multiple intermittent pressing is achieved, the degree of pressing is controlled, and fully automated operation is achieved.
Through the use of this equipment, efficient and simple filler pressing can be achieved when making solid-phase extraction columns, which improves the efficiency and quality of filler pressing, reduces manual intervention, and ensures the uniformity of column chromatography effects and the reliability of experimental results.
Smart Images
Figure CN223026755U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of test tubes, and specifically relates to a solid-phase extraction column filler pressing machine. Background Technique
[0002] As an important sample pretreatment device, the solid-phase extraction column (abbreviated as SPE column) is widely used in multiple fields such as biochemical detection, environmental monitoring, and food safety.
[0003] However, in the preparation process of the existing solid-phase extraction column, the pressing operation of the filler is often cumbersome and it is difficult to ensure uniformity, resulting in an unsatisfactory column chromatography effect and affecting the reproducibility and accuracy of experimental results. Therefore, it is particularly important to develop an efficient and simple solid-phase extraction column filler pressing machine. Content of the Utility Model
[0004] The purpose of the utility model is to provide a solid-phase extraction column filler pressing machine to solve the problems raised in the above background technique.
[0005] To achieve the above purpose, the utility model provides the following technical solution: A solid-phase extraction column filler pressing machine, including a processing table, on the upper end surface of the processing table, there is a recessed placement groove, at the right end of the placement groove, there is an opening groove communicated with the placement groove, inside the placement groove, there is a slidable mold, on the upper end surface of the mold, there are a plurality of mounting holes, inside the mounting holes, there are cavity cylinders that can be taken and placed, on the upper end surface of the processing table, there are a plurality of longitudinal support rods, and the plurality of support rods are installed on the upper end surface of the processing table in a rectangular shape, on the tops of the plurality of support rods, there is an upper plate body, and at the center position of the upper end surface of the upper plate body, there is a downward pressing mechanism;
[0006] On the upper end surface of the processing table, there are a plurality of longitudinal shaft rods, and the plurality of shaft rods are installed on the upper end surface of the processing table in a rectangular shape, and the two adjacent left and right shaft rods are installed between the two adjacent left and right support rods, on the outer walls of the plurality of shaft rods, there are slidable shaft sleeves, outside the plurality of shaft rods, there are a slidable upper buckling plate and a lower buckling plate, on the lower end surface of the lower buckling plate, there are a plurality of pressing columns, and the pressing columns can be pressed into the inside of the cavity cylinders.
[0007] As a preferred implementation manner of the solid-phase extraction column filler pressing machine provided by the utility model: On the inner bottom surface of the mounting hole, there is a downwardly recessed stable hole, and at the lower bottom of the cavity cylinder, there is a stable shaft, and the stable shaft can be inserted into the stable hole.
[0008] As a preferred embodiment of the solid-phase extraction column filler pressing machine provided by the present utility model: at one end where the upper fastening plate and the lower fastening plate are close to each other, there is an inwardly recessed shaft groove, wherein the shaft rod passes through the shaft groove, and the shaft sleeve fits inside the shaft groove.
[0009] As a preferred embodiment of the solid-phase extraction column filler pressing machine provided by the present utility model: the four corners of the upper fastening plate and the lower fastening plate are all designed as inwardly concave arcs, and the arcs fit onto the support rods.
[0010] As a preferred embodiment of the solid-phase extraction column filler pressing machine provided by the present utility model: on the upper end face of the lower fastening plate, a plurality of stepped holes are evenly arranged. A plurality of pressing columns correspond to the plurality of stepped holes and are installed at the lower ends of the stepped holes. The pressing columns are locked at the lower ends of the stepped holes by bolts.
[0011] As a preferred embodiment of the solid-phase extraction column filler pressing machine provided by the present utility model: the numbers of the mounting holes, cavity cylinders, pressing columns, and stepped holes are all designed according to a 6×5 rectangle.
[0012] As a preferred embodiment of the solid-phase extraction column filler pressing machine provided by the present utility model: the lower pressing mechanism includes a lower pressing cylinder, which is fixed on the top of the upper plate body. The output shaft of the lower pressing cylinder passes through the lower end face of the upper plate body, and a base is arranged on the lower end face of the output shaft. A circular connecting piece is arranged on the upper end face of the base, and two locking screws are arranged on the circular connecting piece to lock the upper fastening plate and the lower fastening plate together.
[0013] As a preferred embodiment of the solid-phase extraction column filler pressing machine provided by the present utility model: a reciprocating cylinder is arranged on the left end face of the processing table. The output shaft of the reciprocating cylinder penetrates from the left end face of the processing table into the interior of the processing table and is fixedly connected to the left end face of the mold.
[0014] Compared with the prior art, the beneficial effects of the present utility model are:
[0015] 1. By setting parts and structures such as the lower pressing mechanism, lower pressing cylinder, base, circular connecting piece, upper fastening plate, lower fastening plate, pressing column, mold, cavity cylinder, and stabilizing shaft, and setting machine parameters, one-time pressing or multiple intermittent pressings can be performed, as well as the degree of pressing. When manufacturing the solid-phase extraction column, fully automated operation can be achieved, reducing manual intervention and improving the efficiency and quality of filler pressing. Description of the Drawings
[0016] Figure 1Schematic diagram of the overall structure of Embodiment 1 of the present utility model;
[0017] Figure 2 Schematic diagram of the pressing mechanism, upper fastening plate and lower fastening plate of Embodiment 1 of the present utility model;
[0018] Figure 3 Cross-sectional view of the upper fastening plate and lower fastening plate of Embodiment 1 of the present utility model;
[0019] Figure 4 Cross-sectional view of the upper fastening plate, lower fastening plate, cavity column and mold of Embodiment 1 of the present utility model;
[0020] Figure 5 Schematic diagram of the pressing column, cavity column and mold of Embodiment 1 of the present utility model;
[0021] Figure 6 Schematic diagram of the processing table of Embodiment 1 of the present utility model.
[0022] In the figure: 1. Processing table; 11. Placement groove; 111. Opening groove; 12. Support rod; 121. Upper plate body; 13. Shaft rod; 131. Bushing; 14. Reciprocating cylinder; 2. Mold; 21. Mounting hole; 211. Stabilizing hole; 22. Cavity column; 221. Stabilizing shaft; 3. Lower pressing mechanism; 31. Lower pressing cylinder; 32. Base; 33. Circular connecting piece; 331. Locking screw; 4. Upper fastening plate; 5. Lower fastening plate; 51. Pressing column; 52. Shaft groove; 53. Step hole. Specific embodiments
[0023] The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.
[0024] Embodiment 1:
[0025] Please refer to Figures 1-6, the present utility model provides a technical solution: a solid-phase extraction column packing pressing machine, including a processing table 1. On the upper end surface of the processing table 1, there is an inwardly recessed placement groove 11. At the right end of the placement groove 11, there is an opening groove 111 communicating with the placement groove 11. A slidable mold 2 is arranged in the placement groove 11. On the upper end surface of the mold 2, there are a plurality of mounting holes 21. Inside the mounting holes 21, there are removable cavity cylinders 22. On the upper end surface of the processing table 1, there are a plurality of longitudinal support rods 12. The plurality of support rods 12 are arranged in a rectangle on the upper end surface of the processing table 1. At the top of the plurality of support rods 12, there is an upper plate body 121. At the center position of the upper end surface of the upper plate body 121, there is a downward pressing mechanism 3;
[0026] On the upper end surface of the processing table 1, there are a plurality of longitudinal shaft rods 13. The plurality of shaft rods 13 are arranged in a rectangle on the upper end surface of the processing table 1, and two adjacent shaft rods 13 on the left and right are installed between two adjacent support rods 12 on the left and right. Slidable shaft sleeves 131 are arranged on the outer walls of the plurality of shaft rods 13. A slidable upper fastening plate 4 and a lower fastening plate 5 are arranged outside the plurality of shaft rods 13. On the lower end surface of the lower fastening plate 5, there are a plurality of pressing columns 51. The pressing columns 51 can be pressed into the inside of the cavity cylinder 22.
[0027] Specifically, the downward pressing mechanism 3 can press down the upper fastening plate 4 and the lower fastening plate 5, so that the pressing columns 51 press the packing in the cavity cylinder 22 tightly. By setting parameters such as the number of downward presses and frequency, fully automated operation can be achieved, reducing manual intervention and improving the efficiency and quality of packing pressing.
[0028] As Figure 4 shown: On the inner bottom surface of the mounting hole 21, there is a downwardly recessed stable hole 211. At the lower bottom of the cavity cylinder 22, there is a stable shaft 221. The stable shaft 221 can be inserted into the stable hole 211. This design can stably insert the cavity cylinder 22.
[0029] At one end where the upper fastening plate 4 and the lower fastening plate 5 are close to each other, there is an inwardly recessed shaft groove 52. The shaft rod 13 passes through the shaft groove 52, and the shaft sleeve 131 fits inside the shaft groove 52. This design can make the upper fastening plate 4 and the lower fastening plate 5 slide smoothly.
[0030] The four corners of the upper fastening plate 4 and the lower fastening plate 5 are designed as inwardly concave arcs, and the arcs fit the support rods 12. This design can limit the upper fastening plate 4 and the lower fastening plate 5 when sliding up and down and prevent them from shaking.
[0031] The upper end surface of the lower fastening plate 5 is evenly provided with a plurality of stepped holes 53. A plurality of the pressing columns 51 correspond to the plurality of stepped holes 53 and are installed at the lower ends of the stepped holes 53. The pressing columns 51 are locked at the lower ends of the stepped holes 53 by bolts. This design can stably install the upper pressing columns 51.
[0032] The numbers of the mounting holes 21, the cavity columns 22, the pressing columns 51, and the stepped holes 53 are all designed in a 6×5 rectangle.
[0033] As Figure 1 shown: The lower pressing mechanism 3 includes a lower pressing cylinder 31. The lower pressing cylinder 31 is fixed to the top of the upper plate body 121. The output shaft of the lower pressing cylinder 31 penetrates the lower end surface of the upper plate body 121, and a base 32 is provided on the lower end surface of the output shaft. A circular connecting piece 33 is provided on the upper end surface of the base 32. Two locking screws 331 are provided on the circular connecting piece 33. The locking screws 331 lock the upper fastening plate 4 and the lower fastening plate 5 together. This design can push the upper fastening plate 4 and the lower fastening plate 5 downward.
[0034] A reciprocating cylinder 14 is provided on the left end surface of the processing table 1. The output shaft of the reciprocating cylinder 14 penetrates from the left end surface of the processing table 1 into the interior of the processing table 1 and is fixedly connected to the left end surface of the mold 2. This design can push out and retract the mold 2.
[0035] The specific working principle of this embodiment is as follows: During processing, the device is powered on and the parameters for downward pressing are set to start using. When using, first start the reciprocating cylinder 14. The reciprocating cylinder 14 pushes out the mold 2. After pushing out, the cavity columns 22 can be inserted into the mounting holes 21. When inserting, it is necessary to insert the stabilizing shaft 221 into the stabilizing hole 211. After inserting the cavity columns 22 into each mounting hole 21, then use a sieve plate to fill the cavity columns 22 with materials. After filling, the reciprocating cylinder 14 resets to make each cavity column 22 located directly below the pressing column 51.
[0036] At this time, pressing processing can be carried out. During processing, start the lower pressing cylinder 31. The lower pressing cylinder 31 pushes the upper fastening plate 4 and the lower fastening plate 5 downward. Synchronously, the pressing columns 51 move downward and extend into the interior of the cavity columns 22. According to the preset parameters, perform multiple downward presses to complete the processing operation. After completion, the reciprocating cylinder 14 is started again to push out the mold 2, and then take out the cavity columns 22 after processing to complete the processing operation.
[0037] It should be noted that: The power supply in the above embodiments is a well-known technical means to those skilled in the art. Appropriate controllers can be selected according to actual situations to meet the control requirements. For the specific connections and control sequences, reference should be made to the working principles above, and the electrical connections should be completed according to the sequential working order among the electrical components. The detailed connection means are well-known techniques in the art. The above mainly introduces the working principles and processes, and no further description of electrical control will be given.
[0038] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A solid phase extraction column packing pressing machine, comprising a processing table (1), characterized in that: An inwardly recessed placement groove (11) is provided on the upper end surface of the processing table (1), an open groove (111) communicating with the placement groove (11) is provided at the right end of the placement groove (11), a slidable mold (2) is provided in the placement groove (11), a plurality of mounting holes (21) are provided on the upper end surface of the mold (2), a removable cavity column (22) is provided inside the mounting hole (21), a plurality of longitudinal support rods (12) are provided on the upper end surface of the processing table (1), the plurality of support rods (12) are installed on the upper end surface of the processing table (1) in a rectangular shape, an upper plate body (121) is provided on the top of the plurality of support rods (12), and a downward pressing mechanism (3) is provided at the center position of the upper end surface of the upper plate body (121); The upper end surface of the processing table (1) is provided with a plurality of longitudinal shaft rods (13), the plurality of shaft rods (13) are installed in a rectangular shape on the upper end surface of the processing table (1), and two adjacent shaft rods (13) are installed between two adjacent support rods (12) on the left and right. The outer walls of the plurality of shaft rods (13) are provided with slidable shaft sleeves (131), and the exterior of the plurality of shaft rods (13) is provided with slidable upper buckling plates (4) and lower buckling plates (5), and the lower end surface of the lower buckling plate (5) is provided with a plurality of pressing columns (51), and the pressing columns (51) can be pressed into the interior of the cavity column (22).
2. A solid phase extraction column packing pressing machine according to claim 1, characterized in that: A downwardly recessed stabilizing hole (211) is provided on the inner bottom surface of the mounting hole (21), and a stabilizing shaft (221) is provided on the lower bottom of the cavity column (22), wherein the stabilizing shaft (221) can be inserted into the stabilizing hole (211).
3. A solid phase extraction column packing pressing machine according to claim 2, characterized in that: An inwardly recessed shaft groove (52) is provided at one end of the upper buckling plate (4) and the lower buckling plate (5) that are close to each other, wherein the shaft rod (13) passes through the shaft groove (52), and the shaft sleeve (131) fits inside the shaft groove (52).
4. The solid phase extraction column packing pressing machine according to claim 2, characterized in that: The four corners of the upper buckle plate (4) and the lower buckle plate (5) are designed to be inwardly concave arcs, and the arcs fit the support rod (12).
5. The solid phase extraction column packing pressing machine according to claim 3, characterized in that: The upper end surface of the lower buckle plate (5) is evenly provided with a plurality of stepped holes (53); the plurality of press-fit columns (51) correspond to the plurality of stepped holes (53) and are installed at the lower ends of the stepped holes (53); the press-fit columns (51) are locked at the lower ends of the stepped holes (53) by bolts.
6. A solid phase extraction column packing pressing machine according to claim 5, characterized in that: The numbers of the mounting holes (21), the cavity columns (22), the press-fit columns (51), and the stepped holes (53) are all designed in a 6×5 rectangular shape.
7. The solid phase extraction column packing pressing machine according to claim 1, characterized in that: The pressing mechanism (3) comprises a pressing cylinder (31) which is fixed to the top of the upper plate body (121). The output shaft of the pressing cylinder (31) passes through the lower end surface of the upper plate body (121), and a base (32) is provided on the lower end surface of the output shaft. A circular connecting piece (33) is provided on the upper end surface of the base (32). Two locking screws (331) are provided on the circular connecting piece (33), and the locking screws (331) lock the upper buckle plate (4) and the lower buckle plate (5) together.
8. The solid phase extraction column packing pressing machine according to claim 1, characterized in that: A reciprocating cylinder (14) is arranged on the left end face of the processing table (1), and an output shaft of the reciprocating cylinder (14) passes through the left end face of the processing table (1) into the interior of the processing table (1) and is fixedly connected to the left end face of the mold (2).