Water bath unfreezing box

By using a dual water circulation system and an electric heater design in the water bath thawing box, the problem of uneven water temperature is solved, a more uniform thawing process is achieved, and the structure and activity of the sample is protected.

CN223027375UActive Publication Date: 2025-06-27SUZHOU HANCHAO PHARM TECH CO LTD
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Patent Information

Application Number
CN202422023988.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-20
Publication Date
2025-06-27
Estimated Expiration
2034-08-20

AI Technical Summary

Technical Problem

The existing water bath thawing box can easily lead to uneven water temperature during heating, resulting in overheating or supercooling of the sample during thawing, affecting the structural integrity and activity of the sample.

Method used

A water bath thawing box is designed, and a dual water circulation system of circulating water tank and thawing water tank is used to heat the water in the circulating water tank through an electric heater, and the water circulation pump and overflow hole are used to realize the recycling of water, avoiding the direct setting of the heat source in the thawing water tank, thereby ensuring the uniformity of water temperature.

Benefits of technology

Effectively avoid the problem of uneven water temperature in the frozen water tank, reduce the waste of energy and water resources, and ensure the structural integrity and activity of the sample after thawing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a water bath unfreezing tank, which comprises an unfreezing water tank, a circulating water tank, a cryopreservation container fixing frame, a circulating water pump, a water feeder, a first water inlet pipe, a second water inlet pipe and an electric heater, the water feeder is arranged in the unfreezing water tank, one end of the first water inlet pipe is connected with the circulating water tank, and the other end of the first water inlet pipe is connected with the circulating water pump. The other end of the second water inlet pipe is connected with the water feeder, the other end of the second water inlet pipe is connected with the circulating water pump, the unfreezing water tank is provided with an overflow hole, one end of the backflow pipe is connected with the overflow hole, the other end of the backflow pipe is connected with the circulating water tank, the electric heater is arranged in the circulating water tank, and the cryopreservation container fixing frame is embedded in the unfreezing water tank. A cryopreservation container loading area is defined in the unfreezing water tank, a limiting rod is arranged at the bottom of the cryopreservation container loading area, and a buckle is arranged on the cryopreservation container fixing frame. The water circulation during water bath unfreezing is realized, the cryopreservation container is not damaged, and the occurrence probability of the problem of non-uniform water temperature is reduced.
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Description

Technical Field

[0001] The utility model relates to the field of biomedical equipment, and particularly relates to a water bath thawing box. Background Art

[0002] In the field of biomedicine, samples such as cells, drug stock solutions, tissues or vaccines are mostly stored at low temperature in freezing containers such as freezing boxes, and when in need of use, the above-mentioned freezing containers are thawed at low temperature to an appropriate temperature to restore the activity and function of the samples. The thawing speed during thawing and the temperature control during the thawing process play a crucial role in the integrity of the structure and function of the samples.

[0003] The common thawing methods for the above samples mainly include room temperature thawing, water bath thawing and dry bath thawing. Among them, water bath heating is achieved by heating the freezing container containing the sample through water separation. Although the water separation heating method is relatively fast, in common water bath heating, the heating source is directly set in the water tank for water bath thawing, and the water temperature near the heat source is often higher than other parts, which easily leads to uneven heating. Moreover, when the sample freezing container is often heated, it will directly contact the above water tank and hinder the passage of the heating water flow, further increasing the probability of uneven heating, resulting in problems such as partial overheating or overcooling of the sample during thawing, causing structural damage or a decrease in activity of the sample, and affecting the subsequent use of the sample. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a water bath thawing box, which can solve one or more of the above problems.

[0005] According to one aspect of the utility model, a water bath thawing box is provided, which includes a thawing water tank, a circulating water tank, a freezing container fixing rack, a circulating water pump, a water supply device, a first water inlet pipe, a second water inlet pipe and an electric heater.

[0006] The water supply device is arranged in the thawing water tank. One end of the first water inlet pipe is connected to the circulating water tank, and the other end is connected to the circulating water pump. The other end of the second water inlet pipe is connected to the water supply device, and the other end is connected to the circulating water pump.

[0007] The thawing water tank is provided with an overflow hole. One end of the return pipe is connected to the overflow hole, and the other end is connected to the circulating water tank.

[0008] The electric heater is arranged in the circulating water tank.

[0009] The freezing container fixing rack is embedded in the thawing water tank and encloses a freezing container loading area in the thawing water tank. A limiting rod is arranged at the bottom of the freezing container loading area, and a buckle is arranged on the freezing container fixing rack.

[0010] The beneficial effects of the present utility model are as follows: In the present utility model, the circulating water tank and the thawing water tank can both be filled with water for water bath heating. The electric heater can heat the water in the circulating water tank, and by virtue of the arrangement of the circulating water pump and the overflow hole, the hot water can circulate between the circulating water tank and the thawing water tank, continuously maintaining the temperature of the water in the circulating water tank. Thus, it can effectively avoid the problem of uneven water temperature in the thawing water tank caused by directly setting the heat source in the thawing water tank. Also, since the water flow is recycled, it avoids the problem of wasting both energy and water resources when the water temperature drops and the water needs to be discarded. The frozen storage containers such as frozen storage boxes to be thawed can be clamped on the buckles and fixed on the frozen storage container fixing rack, thereby ensuring the fixation of the frozen storage container in the frozen storage container loading area and preventing it from drifting under the action of water flow, avoiding problems such as collision of the frozen storage container during the thawing process. At the same time, by setting the limiting rod, it can prevent the bottom of the frozen storage container from directly contacting the thawing water tank, thereby avoiding the frozen storage container from obstructing the water flow, causing no damage to the frozen storage container, and further reducing the occurrence probability of the problem of uneven water temperature during thawing, effectively ensuring the structural integrity and good activity of the samples loaded in the thawed frozen storage container.

[0011] In some embodiments, the present utility model further includes a liquid level gauge, which is installed on the circulating water tank, and the liquid level gauge is configured to measure the water level of the circulating water tank.

[0012] In some embodiments, the present utility model further includes a controller and an operation screen. The circulating water pump, the electric heater, and the liquid level gauge are respectively electrically connected to the controller, and the controller is electrically connected to the operation screen. Thus, the working parameter signal of the circulating water pump, the heating temperature signal of the electric heater, and the water level height signal of the circulating water tank measured by the liquid level gauge can all be transmitted to the controller and output to the operation screen for the user to view, and it is convenient for the user to control the operation of the circulating water pump and the electric heater through the operation screen to adapt to the thawing needs of different samples.

[0013] In some embodiments, the present utility model further includes a return pipe. The thawing water tank is provided with an overflow hole, one end of the return pipe is connected to the overflow hole, and the other end is connected to the circulating water tank. The arrangement of the return pipe and the overflow hole can facilitate the excess water to flow back to the circulating water tank when the water volume in the thawing water tank is too large, avoiding damage to other structures caused by excessive water in the thawing water tank.

[0014] In some embodiments, the frozen storage container fixing rack can hold frozen storage containers. The frozen storage container has a brittle or vulnerable part or a welding position after freezing, and the height of the overflow hole is set lower than the brittle or vulnerable part or the welding position after freezing. Thus, it can avoid the large impact on the above-mentioned brittle or vulnerable part or the welding position caused by the water flow formed when the water flows out of the overflow hole, resulting in damage to the frozen storage containers such as frozen storage boxes.

[0015] In some embodiments, the utility model further includes a make-up water pipe, and the make-up water pipe is connected to the thawing water tank. The arrangement of the make-up water pipe facilitates the user to replenish water into the thawing water tank through it.

[0016] In some embodiments, the utility model further includes a thawing water tank drain pipe and a circulation water tank drain pipe. The thawing water tank drain pipe is connected to the thawing water tank, and the circulation water tank drain pipe is connected to the circulation water tank. The thawing water tank drain pipe facilitates the user to directly drain the thawing water tank through it, and the circulation water tank drain pipe facilitates the user to directly drain the circulation water tank through it.

[0017] In some embodiments, the utility model further includes a bracket, casters and a top cover. Both the thawing water tank and the circulation water tank are installed in the bracket. The casters are connected to the bottom of the bracket. There is an opening on the thawing water tank, and the top cover is detachably installed on the bracket and covers the opening. The opening facilitates the taking and placing of external freezing containers such as freezing boxes in the thawing water tank. By providing the top cover, it is convenient to close the opening during the water bath thawing process, reducing the influence of the external environment on the water bath thawing. The arrangement of the casters facilitates the movement of the utility model. Description of the Drawings

[0018] Figure 1 It is a schematic structural diagram of a water bath thawing box according to an embodiment of the utility model.

[0019] Figure 2 It is a schematic structural diagram of a water bath thawing box according to an embodiment of the utility model.

[0020] Figure 3 It is a schematic diagram of a water bath thawing box according to an embodiment of the utility model.

[0021] In the figure: 1. Thawing water tank, 2. Circulation water tank, 3. Freezing container fixing rack, 4. Circulation water pump, 5. Water supply device, 6. First water inlet pipe, 7. Second water inlet pipe, 8. Electric heater, 9. Liquid level gauge, 20. Return pipe, 30. Make-up water pipe, 40. Thawing water tank drain pipe, 50. Circulation water tank drain pipe, 60. Bracket, 70. Casters, 80. Top cover, 11. Freezing container loading area, 12. Overflow hole, 13. Return guide plate. Detailed Embodiments

[0022] The following further describes the utility model in detail with reference to the drawings.

[0023] Refer to Figure 1 、 Figure 2 and Figure 3, A water bath thawing box of the present utility model includes a thawing water tank 1, a circulation water tank 2, a cryopreservation container fixing rack 3, a circulation water pump 4, a water supply device 5, a first water inlet pipe 6, a second water inlet pipe 7, and an electric heater 8.

[0024] The thawing water tank 1 is provided with a containing cavity which can be used to load water. The water supply device 5 includes a diverter and a water outlet head. The diverter of the water supply device 5 is arranged outside the thawing water tank 1, and the water outlet head of the water supply device 5 is fixedly arranged in the containing cavity of the thawing water tank 1 by welding. There can be multiple water outlet heads, and the multiple water outlet heads are respectively connected to the diverter. Thus, the water transported from the outside to the diverter can be divided by the diverter and then flow out from each water outlet head into the containing cavity of the thawing water tank 1.

[0025] The circulation water tank 2 is provided with a water containing cavity which can also be used to load water. One end of the first water inlet pipe 6 is fixedly connected to the circulation water tank 2 through a clamp, and the other end of the first water inlet pipe 6 is fixedly connected to the water inlet of the circulation water pump 4 through a clamp. Then the water containing cavity is connected to the water inlet of the circulation water pump 4 through the first water inlet pipe 6.

[0026] One end of the second water inlet pipe 7 is fixedly connected to the diverter of the water supply device 5 through a clamp, and the other end of the second water inlet pipe 7 is fixedly connected to the water outlet of the circulation water pump 4 through a clamp. Then the diverter is connected to the water outlet of the circulation water pump 4 through the second water inlet pipe 7.

[0027] The electric heater 8 is embedded in the water containing cavity of the circulation water tank 2, so that the electric heater 8 can heat the water loaded in the circulation water tank 2.

[0028] The cryopreservation container fixing rack 3 is fixedly embedded in the thawing water tank 1 through a limiting device. The cryopreservation container fixing rack 3 can enclose multiple cryopreservation container loading areas 11 in the containing cavity of the thawing water tank 1. The bottom of the cryopreservation container loading area 11 is provided with a limiting rod, and the cryopreservation container fixing rack 11 is provided with a buckle which can be used to fix cryopreservation containers such as cryopreservation boxes.

[0029] The water bath thawing box of the present utility model further includes a liquid level gauge 9. The liquid level gauge 9 is fixedly installed on the side of the circulation water tank 2 through a clamp, and the liquid level gauge 9 is configured to measure the water level of the circulation water tank 2.

[0030] The water bath thawing box of the present utility model further includes a controller and an operation screen. Among them, the power motor of the circulation water pump 4, the electric heater 8, and the liquid level gauge 9 can be electrically connected to the controller through wires respectively, and the controller is also electrically connected to the operation screen through a wire. Then the power motor of the circulation water pump 4, the electric heater 8, the liquid level gauge 9, and the operation screen can exchange signals with the controller.

[0031] The water bath thawing box of the present utility model further includes a return pipe 20. An overflow hole 12 is provided on the thawing water tank 1, and a return guide plate 13 is connected to the overflow hole 12. One end of the return pipe 20 is connected to the return guide plate 13, that is, this end of the return pipe 20 is connected to the overflow hole 12 through the return guide plate 13. The other end of the return pipe 20 is connected to the circulation water tank 2. The overflow hole 12 is communicated with the accommodating cavity of the thawing water tank 1, so the overflow hole 12 is also communicated with the water-containing cavity of the circulation water tank 2 through the return pipe 20. Then the water flowing out of the overflow hole 12 can be guided by the return guide plate 13 to the return pipe 20 and flow back to the water-containing cavity of the circulation water tank 2 through the return pipe 20.

[0032] The frozen container fixing rack 3 can be welded by a plurality of pipe strips. The frozen container fixing rack 3 can hold frozen containers. Frozen containers generally have welding positions for pipes or other pipe fittings, or parts that are brittle or vulnerable after freezing. The setting height of the overflow hole 12 should be lower than the setting height of the brittle or vulnerable parts or welding positions of the frozen containers after freezing.

[0033] The water bath thawing box of the present utility model further includes a water replenishing pipe 30. The water replenishing pipe 30 is fixedly connected to the side of the thawing water tank 1. After being arranged, the water replenishing pipe 30 is communicated with the accommodating cavity of the thawing water tank 1, and a valve is provided on the water replenishing pipe 30. Under normal conditions, the user can close the water replenishing pipe 30 through the valve.

[0034] The water bath thawing box of the present utility model further includes a thawing water tank drain pipe 40 and a circulation water tank drain pipe 50. The thawing water tank drain pipe 40 is fixedly connected to the side of the thawing water tank 1, and the circulation water tank drain pipe 50 is fixedly connected to the side of the circulation water tank 2. After being arranged, the thawing water tank drain pipe 40 is communicated with the accommodating cavity of the thawing water tank 1, and the circulation water tank drain pipe 50 is communicated with the water-containing cavity of the circulation water tank 2. Valves are also respectively provided on the thawing water tank drain pipe 40 and the circulation water tank drain pipe 50. Under normal conditions, the user can close the thawing water tank drain pipe 40 and the circulation water tank drain pipe 50 through the above valves respectively.

[0035] The water bath thawing box of the present utility model further includes a bracket 60, casters 70 and a top cover 80. Both the thawing water tank 1 and the circulation water tank 2 are fixedly installed in the bracket 60 through clamps, and the thawing water tank 1 is arranged above the circulation water tank 2 so that when the thawing water tank 1 overflows, the overflowing water can effectively flow back to the circulation water tank 2 by gravity.

[0036] The casters 70 are preferably Fukuma wheels. There can be a plurality of casters 70. All the casters 70 are connected to the bottom of the bracket 60 through clamps. The setting of the casters 70 can facilitate the movement of the bracket 60.

[0037] An opening is provided on the top of the thawing water tank 1. The top cover 80 is detachably covered on the bracket 60, and the top cover 80 covered on the bracket 60 can cover the opening.

[0038] The use of the water bath thawing box of the present utility model can be specifically preferably carried out in the following steps.

[0039] Connect the water replenishing pipe 30 to an external water supply device, and open the valve on the water replenishing pipe 30, so that the external water supply device can replenish water into the accommodating cavity in the thawing water tank 1 through the water replenishing pipe 30. When the water level reaches the overflow height, the water in the accommodating cavity can flow out through the overflow hole 12 and return to the water containing cavity of the circulation water tank 2 through the return pipe 20. At this time, the liquid level gauge 9 can measure the water level height in the current circulation water tank 2. When the water level height in the circulation water tank 2 meets the requirements, the valve on the water replenishing pipe 30 can be closed to stop the external water supply device from replenishing water to the thawing water tank 1.

[0040] Start the circulation water pump 4, so that the circulation water pump 4 can pump the water in the water containing cavity of the circulation water tank 2 into the water supply device 5, and the water is output from the water supply device 5 into the accommodating cavity in the thawing water tank 1. Combining with the function of the overflow hole 12, the water can circulate between the circulation water tank 2 and the thawing water tank 1. At the same time, start the electric heater 8, and the electric heater 8 can heat the water in the water containing cavity of the circulation water tank 2 to maintain the water in the water containing cavity at a specific required temperature. And through circulation, the water in the accommodating cavity in the thawing water tank 1 can also be maintained at a specific required temperature.

[0041] After that, the top cover 80 can be opened, and a plurality of cryopreservation containers such as cryoboxes loaded with samples to be thawed are respectively fixed on the cryopreservation container fixing rack 3 through buckles. At this time, the plurality of cryopreservation containers can be respectively fixed in a plurality of cryopreservation container loading areas 11 to prevent them from colliding with each other. And at this time, the bottom of the cryopreservation container can be restricted by the limiting rod to prevent the bottom of the cryopreservation container from contacting the thawing water tank 1. Then, during the water circulation process, the hot water can flow through each cryopreservation container to thaw the cryopreservation container.

[0042] In the present utility model, during the thawing process, the water can circulate between the circulation water tank 2 and the thawing water tank 1, realizing the recycling of hot water, reducing the waste of water and energy resources. And the electric heater 8 is independently arranged from the thawing water tank 1, avoiding the problem of uneven water temperature in the thawing water tank 1 caused by directly setting the heat source in the thawing water tank 1. At the same time, by setting the limiting rod, it can prevent the bottom of the cryopreservation container from directly contacting the thawing water tank, thereby avoiding the cryopreservation container from hindering the flow of water, further reducing the occurrence probability of the problem of uneven water temperature during thawing. The buckles are provided to prevent the cryopreservation container from floating under the action of water flow and causing problems such as collision, so as to effectively make the structure of the sample loaded in the thawed cryopreservation container complete and have good activity.

[0043] The above are only some embodiments of the present utility model. For those of ordinary skill in the art, without departing from the inventive concept of the present utility model, several modifications and improvements can still be made, and these all belong to the protection scope of the present utility model.

Claims

1. Water bath thawing box, characterized in that: It includes a thawing water tank, a circulating water tank, a freezing container fixing frame, a circulating water pump, a water supply device, a first water inlet pipe, a second water inlet pipe, a return pipe and an electric heater. The water supply device is arranged in the thawing water tank, one end of the first water inlet pipe is connected to the circulating water tank, and the other end is connected to the circulating water pump, the other end of the second water inlet pipe is connected to the water supply device, and the other end is connected to the circulating water pump, The thawing water tank is provided with an overflow hole, one end of the return pipe is connected to the overflow hole, and the other end is connected to the circulating water tank. The electric heater is arranged in the circulating water tank. The freezing container fixing frame is embedded in the thawing water tank and encloses a freezing container loading area in the thawing water tank. A limiting rod is provided at the bottom of the freezing container loading area, and a buckle is provided on the freezing container fixing frame.

2. The water bath thawing box according to claim 1, characterized in that: It comprises a liquid level meter which is installed on a circulating water tank and is configured to measure the water level of the circulating water tank.

3. The water bath thawing box according to claim 2, characterized in that: It comprises a controller and an operating panel, wherein the circulating water pump, the electric heater and the liquid level meter are electrically connected to the controller respectively, and the controller is electrically connected to the operating panel.

4. The water bath thawing box according to claim 1, characterized in that: The freezing container fixing rack can be loaded with freezing containers, and the freezing containers have a part or welding position that is brittle or easily damaged after freezing, and the overflow hole is arranged at a height lower than the part or welding position that is brittle or easily damaged after freezing.

5. The water bath thawing box according to claim 1, characterized in that: It comprises a water supply pipe, which is connected to the thawing water tank.

6. The water bath thawing box according to claim 1, characterized in that: It comprises a thawing water tank drain pipe and a circulating water tank drain pipe, wherein the thawing water tank drain pipe is connected to the thawing water tank, and the circulating water tank drain pipe is connected to the circulating water tank.

7. The water bath thawing box according to claim 1, characterized in that: It comprises a bracket, casters and a top cover. The thawing water tank and the circulating water tank are both installed in the bracket. The casters are connected to the bottom of the bracket. An opening is provided on the thawing water tank. The top cover is detachably installed on the bracket and covers the opening.