Semiconductor temperature changing device for nuclear magnetic resonance

Abstract

The utility model discloses a semiconductor temperature changing device for nuclear magnetic resonance, which comprises a constant temperature mechanism, a probe structure and a temperature changing mechanism, a closed outer tube is arranged in the middle of the inner side of an iron yoke, a wave guide tube is sleeved on the inner side of the closed outer tube, and a closed cover plate is connected with one end part of the closed outer tube and one end part of the wave guide tube. A temperature sensor is installed on one side of the interior of the closed outer pipe, a spiral radio frequency coil is connected to the outer side of the wave guide pipe in a sleeved mode, the current direction of the semiconductor chilling plate can be controlled in the temperature control process, nitrogen can be heated and cooled, the nitrogen can be conveniently transported through the plastic hose rotary vacuum pump, and the nitrogen can be conveniently conveyed through the plastic hose rotary vacuum pump. The temperature in the closed outer tube is changed, and the temperature sensor detects temperature information and feeds back the temperature information to the PID temperature controller, so that a control loop of the coil temperature is realized, the temperature of the probe is accurately adjusted, and the probe can not only perform an experiment at room temperature, but also meet the requirement of temperature control in a relatively large range.

Description

Technical Field

[0001] The utility model relates to the technical field of nuclear magnetic resonance probes, in particular to a nuclear magnetic resonance semiconductor variable temperature device. Background Technique

[0002] In a nuclear magnetic resonance analyzer, a probe is a core component for the interaction of a magnetic field, radio frequency pulse frequency and a sample. The volume space range of the probe of a small nuclear magnetic resonance instrument is relatively small. Its probe coil is generally a single coil, located at the center of a uniform magnetic field, generally wound on the outer surface of a waveguide tube, and the functions of exciting nuclear spins and detecting nuclear precession of the coil are switched through a transmit / receive switch. The coil is both the terminal of a radio frequency signal transmitter and the signal detection starting point of a receiver. Therefore, the sensitivity of the probe determines the accuracy of the entire instrument.

[0003] The composition of a traditional probe coil is relatively simple, generally using a shielding box, coil, etc. When current passes through the coil, heat is generated, resulting in a reduction in the detection accuracy of the coil, or the thermal noise from the sample and the preamplifier circuit also affects the detection of the coil. Currently, indoor constant temperature control, liquid nitrogen cooling, natural cooling, etc. are adopted, but these temperature control methods can no longer meet the demand for precise temperature adjustment, and traditional probes can often only conduct experiments at room temperature and cannot meet the temperature control within a large range. Content of the Utility Model

[0004] The utility model provides a nuclear magnetic resonance semiconductor variable temperature device, which can effectively solve the problems put forward in the above background technique that the composition of a traditional probe coil is relatively simple, generally using a shielding box, coil, etc. When current passes through the coil, heat is generated, resulting in a reduction in the detection accuracy of the coil, or the thermal noise from the sample and the preamplifier circuit also affects the detection of the coil. Currently, indoor constant temperature control, liquid nitrogen cooling, natural cooling, etc. are adopted, but these temperature control methods can no longer meet the demand for precise temperature adjustment, and traditional probes can often only conduct experiments at room temperature and cannot meet the temperature control within a large range.

[0005] To achieve the above object, the utility model provides the following technical scheme: A nuclear magnetic resonance semiconductor variable temperature device includes a constant temperature mechanism, a probe structure and a variable temperature mechanism. The constant temperature mechanism is composed of an iron yoke and a heat dissipation copper tube, and the heat dissipation copper tube is spirally wound around the outer side edge of the iron yoke.

[0006] The probe structure includes a closed outer tube, a waveguide tube, a closed cover plate, an air outlet conduit and a radio frequency coil.

[0007] In the middle of the inner side of the yoke, a closed outer tube is provided. A waveguide tube is sleeved inside the closed outer tube, and a closed cover plate is connected to one end of the closed outer tube and the waveguide tube. A temperature sensor is installed on one side inside the closed outer tube, and a spiral radio frequency coil is sleeved outside the waveguide tube;

[0008] An air outlet duct is embedded and connected inside the closed cover plate. An air inlet duct penetrates and is connected to the side of the closed cover plate where the air outlet duct is located, and an electronic circuit access hole is penetrated and opened inside the closed cover plate;

[0009] The variable temperature mechanism mainly consists of a PID temperature controller, a semiconductor refrigeration sheet, a semiconductor heat dissipation copper tube, a plastic hose, a rotary vacuum pump, and a commutator.

[0010] According to the above technical solution, the PID temperature controller is used to set the experimental temperature, and the PID temperature controller adjusts the magnitude of the current of the semiconductor refrigeration sheet by means of program control. The commutator controls the direction of the current passing through the semiconductor refrigeration sheet, so as to perform refrigeration and heating;

[0011] The semiconductor heat dissipation copper tube is used for temperature reduction treatment when the semiconductor is refrigerated to avoid damaging the semiconductor refrigeration sheet;

[0012] The plastic hose is used for conducting and transporting nitrogen after temperature reduction and after temperature rise;

[0013] The rotary vacuum pump is used for performing air exchange and circulation treatment on the temperature-controlled air flow, so as to transport the variable-temperature nitrogen into the space of the probe structure.

[0014] According to the above technical solution, one end of the heat dissipation copper tube is the water inlet end, and the other end is the water outlet end. The circulating water enters from the water inlet end and discharges from the water outlet end, and the heat dissipation copper tube realizes constant temperature through the circulating water inside it.

[0015] According to the above technical solution, a closed space is formed by enclosing the closed outer tube, the waveguide tube, and the closed cover plate, and heat insulation cotton is pasted on the outside of the closed outer tube.

[0016] According to the above technical solution, the closed cover plate seals the gap between the closed outer tube and the waveguide tube.

[0017] The temperature sensor inside the closed outer tube is used to receive the experimental temperature.

[0018] According to the above technical solution, the air outlet end of the air inlet duct extends to the inside of the closed outer tube, and the electronic circuit access hole is used for threading and connecting of the electronic circuit.

[0019] Compared with the prior art, the beneficial effects of the present utility model are as follows: The structure of the present utility model is scientific and reasonable, and it is safe and convenient to use:

[0020] 1. By winding the heat dissipation copper tube around the outside of the yoke, the constant temperature is achieved through the water circulation inside the heat dissipation copper tube to ensure the constant temperature on the outside of the probe structure. At the same time, the air outlet duct and air inlet duct on the edge of the probe structure are used to conveniently input and output the nitrogen for temperature control, facilitating the use of nitrogen to regulate the temperature inside the probe structure. The temperature sensor inside the probe structure can easily sense the temperature inside the probe structure, facilitating the timely response to the temperature information;

[0021] Moreover, a temperature-changing mechanism is composed of a PID temperature controller, a semiconductor refrigeration chip, a semiconductor heat dissipation copper tube, a plastic hose, and a rotary vacuum pump. It can control the current direction of the semiconductor refrigeration chip during the temperature control process to heat and cool the nitrogen. The plastic hose and the rotary vacuum pump facilitate the transportation of nitrogen to change the temperature inside the closed outer tube. The temperature sensor detects the temperature information and feeds it back to the PID temperature controller to form a control loop for the coil temperature, achieving precise adjustment of the probe temperature. This enables the probe to not only conduct experiments at room temperature but also meet a wide range of temperature controls, improving the sensitivity during the probe detection process and thus enhancing the accuracy of the entire instrument. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The drawings are used to provide a further understanding of the present invention and constitute a part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation to the present invention.

[0023] In the drawings:

[0024] Figure 1 is a schematic structural diagram of the present invention;

[0025] Figure 2 is a top view of the present invention;

[0026] Figure 3 is a schematic structural diagram of the closed outer tube of the present invention;

[0027] Figure 4 is a schematic structural diagram of the waveguide of the present invention;

[0028] Figure 5 is a schematic diagram of the operation of the temperature-changing mechanism of the present invention;

[0029] The reference numerals in the figures: 1. Yoke; 2. Heat dissipation copper tube; 3. Closed outer tube; 4. Waveguide; 5. Closed cover plate; 6. Air outlet duct; 7. Air inlet duct; 8. Electronic circuit access hole; 9. Temperature sensor; 10. RF coil. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0030] The preferred embodiments of the present utility model will be described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present utility model, and are not used to limit the present utility model.

[0031] Embodiment: As Figures 1-5 shown, the present utility model provides a technical solution, a nuclear magnetic resonance semiconductor variable temperature device, which includes a constant temperature mechanism, a probe structure and a variable temperature mechanism. The constant temperature mechanism is composed of an iron yoke 1 and a heat dissipation copper tube 2, and the heat dissipation copper tube 2 is spirally wound around the outer side edge of the iron yoke 1. One end of the heat dissipation copper tube 2 is the water inlet end, and the other end is the water outlet end. The circulating water enters from the water inlet end and is discharged from the water outlet end. And the heat dissipation copper tube 2 realizes constant temperature through the circulating water inside it, which is convenient to make the circulating flowing water realize constant temperature and improve the constant temperature effect of the constant temperature mechanism;

[0032] The probe structure includes a closed outer tube 3, a waveguide tube 4, a closed cover plate 5, an air outlet duct 6 and a radio frequency coil 10;

[0033] A closed outer tube 3 is arranged in the middle of the inner side of the iron yoke 1. A waveguide tube 4 is sleeved inside the closed outer tube 3. And one end of the closed outer tube 3 and the waveguide tube 4 is connected with a closed cover plate 5. A closed space is formed by enclosing the closed outer tube 3, the waveguide tube 4 and the closed cover plate 5. Heat insulation cotton is pasted on the outside of the closed outer tube 3, which is convenient for the arrangement of the internal components of the probe. At the same time, it avoids heat directly entering the inside of the probe structure from the closed outer tube 3. The closed cover plate 5 seals the gap between the closed outer tube 3 and the waveguide tube 4 to maintain the tightness of the internal structure of the sleeve head and improve the effect during temperature control. A temperature sensor 9 is installed on one side inside the closed outer tube 3. The temperature sensor 9 inside the closed outer tube 3 is used to receive the experimental temperature, which is convenient for quickly obtaining the temperature information inside the probe structure. A spiral radio frequency coil 10 is sleeved outside the waveguide tube 4;

[0034] An air outlet duct 6 is embedded and connected inside the closed cover plate 5. An air inlet duct 7 penetrates and connects at the side of the closed cover plate 5 where the air outlet duct 6 is located. And an electronic circuit access hole 8 is penetrated and opened inside the closed cover plate 5. The air outlet end of the air inlet duct 7 extends to the inside of the closed outer tube 3. The electronic circuit access hole 8 is used for the wire connection of the electronic circuit, which is convenient for quickly transporting the gas transported by the air inlet duct 7 to the inside of the closed outer tube 3 and at the same time convenient for the connection of the electronic circuit.

[0035] The variable temperature mechanism mainly consists of a PID temperature controller, a semiconductor refrigeration sheet, a semiconductor heat dissipation copper tube, a plastic hose, a rotary vacuum pump and a commutator;

[0036] The PID temperature controller adjusts the magnitude of the current of the semiconductor refrigeration sheet through program control means. The commutator controls the direction of the current passing through the semiconductor refrigeration sheet, so as to perform refrigeration and heating;

[0037] The plastic hose is used for conducting and transporting nitrogen gas after temperature reduction and after temperature increase. The rotary vacuum pump is used for performing air exchange and circulation treatment on the temperature-controlled air flow, so as to transport the temperature-variable nitrogen gas into the space of the probe structure.

[0038] The working principle and usage process of the present utility model: In the actual application process of the nuclear magnetic resonance semiconductor temperature-variable device, first, a heat dissipation copper tube 2 is wound around the outer side of the yoke 1, and the constant temperature is achieved by using the water circulation input in the heat dissipation copper tube 2 to ensure the constancy of the temperature outside the probe structure;

[0039] Secondly, in the process of temperature-variable control, the experimental temperature is set through the PID temperature controller, and the temperature inside the probe structure is sensed by the temperature sensor 9 inside the probe structure, so as to react to the temperature information in a timely manner. When controlling the temperature, the PID temperature controller controls the current direction of the semiconductor refrigeration sheet by means of program control of the commutator, so as to heat and cool the nitrogen gas;

[0040] After the nitrogen gas is heated or cooled by the semiconductor refrigeration sheet, the plastic hose and the rotary vacuum pump are used to transport the processed nitrogen gas. The plastic hose is connected to the intake duct 7 inside the probe structure, and the nitrogen gas for temperature control is transported into the probe structure through the plastic hose and the intake duct 7;

[0041] And after the action of the nitrogen gas ends, it is discharged from the probe structure through the outlet duct 6, which is convenient for inputting and outputting the nitrogen gas for temperature control. The temperature inside the probe structure is regulated by using the nitrogen gas, so as to realize the control loop of the coil temperature, accurately adjust the temperature inside the probe structure, so that the probe can not only perform experiments at room temperature, but also meet a relatively large range of temperature control, improve the sensitivity during the probe detection process, and thus improve the accuracy of the whole instrument.

[0042] Finally, it should be noted that: The above are only the preferred examples of the present utility model and are not used to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included in the protection scope of the present utility model.

Claims

1. A semiconductor temperature-changing device for nuclear magnetic resonance, characterized in that: It comprises a constant temperature mechanism, a probe structure and a temperature-changing mechanism, wherein the constant temperature mechanism is composed of an iron yoke (1) and a heat dissipation copper tube (2), and the heat dissipation copper tube (2) is spirally wound around the outer edge of the iron yoke (1); The probe structure comprises a closed outer tube (3), a waveguide (4), a closed cover plate (5), an air outlet conduit (6) and a radio frequency coil (10); A closed outer tube (3) is provided at the middle of the inner side of the iron yoke (1), a waveguide (4) is sleeved on the inner side of the closed outer tube (3), and a closed cover plate (5) is connected to one end of the closed outer tube (3) and the waveguide (4), a temperature sensor (9) is installed on one side of the inner side of the closed outer tube (3), and a spiral radio frequency coil (10) is sleeved on the outer side of the waveguide (4); An air outlet duct (6) is embedded and connected inside the closed cover plate (5), an air inlet duct (7) is connected through the edge of the closed cover plate (5) located on one side of the air outlet duct (6), and an electronic circuit inlet and outlet hole (8) is opened through the closed cover plate (5); The temperature changing mechanism is mainly composed of a PID temperature controller, a semiconductor refrigeration sheet, a semiconductor heat dissipation copper tube, a plastic hose, a rotary vacuum pump and a commutator.

2. A semiconductor temperature-changing device for nuclear magnetic resonance according to claim 1, characterized in that: The PID temperature controller is used to set the experimental temperature, and the PID temperature controller adjusts the current of the semiconductor refrigeration piece by means of program control, and the commutator controls the direction of the current passing through the semiconductor refrigeration piece, thereby performing cooling and heating; The plastic hose is used to conduct and transport the nitrogen after the temperature is changed; The semiconductor heat dissipation copper tube is used for cooling the semiconductor when it is refrigerated; The rotary vacuum pump is used to perform ventilation circulation processing on the temperature-controlled airflow, so as to transport the nitrogen gas with variable temperature into the space of the probe structure.

3. The semiconductor temperature-changing device for nuclear magnetic resonance according to claim 1, characterized in that: One end of the heat dissipation copper tube (2) is a water inlet end, and the other end is a water outlet end. Circulating water enters from the water inlet end and is discharged from the water outlet end. The heat dissipation copper tube (2) achieves constant temperature through the circulating water inside it.

4. The semiconductor temperature-changing device for nuclear magnetic resonance according to claim 1, characterized in that: The closed outer tube (3), the waveguide (4) and the closed cover plate (5) together form a closed space, and the outer side of the closed outer tube (3) is affixed with heat insulation cotton.

5. The semiconductor temperature-changing device for nuclear magnetic resonance according to claim 4, characterized in that: The sealing cover plate (5) seals the gap between the outer tube (3) and the waveguide (4). The temperature sensor (9) inside the closed outer tube (3) is used to receive the experimental temperature.

6. The semiconductor temperature-changing device for nuclear magnetic resonance according to claim 1, characterized in that: The air outlet end of the air inlet duct (7) extends to the interior of the closed outer tube (3), and the electronic circuit inlet and outlet holes (8) are used for threading and connecting the electronic circuit.

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