Liquid injection device and liquid injection equipment

Abstract

The utility model belongs to the field of liquid filling, and particularly relates to a liquid filling device and liquid filling equipment, the liquid filling device comprises a lifting mechanism, a filling mechanism and a limiting piece, the structure is simple, when the liquid filling device is used, a liquid storage pipe storing a reagent is installed at the lower end of a piston cylinder, a reagent box to be filled with liquid is placed below the liquid storage pipe, then the lifting mechanism is started, and the liquid filling mechanism is started; the filling mechanism and the liquid storage pipe are driven by the lifting mechanism to move downwards at first, when the piston cylinder moves to the stopping part on the outer wall of the piston cylinder to abut against the limiting piece, the lower end of the liquid storage pipe is in butt joint with the filling opening of the kit, and then a plunger of the filling mechanism continues to move downwards under the action of the lifting mechanism. The reagent in the liquid storage pipe is pushed and injected into the reagent box, the whole injection process only needs to drive the injection mechanism to move downwards through the lifting mechanism, positioning and then liquid injection are achieved through cooperation of the limiting piece and the stopping part on the outer wall of the piston barrel, and the injection precision is greatly improved.

Description

Technical Field

[0001] This application relates to the technical field of liquid perfusion, and particularly to a liquid injection device and a liquid injection equipment. Background Art

[0002] Molecular detection uses molecular biology techniques to detect and analyze nucleic acid substances in samples such as body fluids, blood, and tissues. According to different technical platforms, molecular detection can be divided into polymerase chain nucleic acid amplification technology, gene sequencing, fluorescence in situ hybridization, gene chips, and nucleic acid mass spectrometry, etc. Molecular detection is currently the fastest developing and most cutting-edge direction in the field of in vitro diagnosis.

[0003] The kit is an essential consumable in molecular detection. The kit stores the reagents required for detection. The prior art generally uses a combination of manual eccentric wheel pressing and gas path to inject the reagents into the kit. Among them, the eccentric wheel pressing drives the liquid adding tube to descend, so that the liquid adding tube is inserted into the opening on the kit, and then the power is provided by the pump in the gas path to achieve liquid injection. This kind of liquid adding device has a relatively complex layout structure, many gas path structure components, and poor accuracy. Summary of the Utility Model

[0004] The embodiments of this application provide a liquid injection device and a liquid injection equipment, which are used to solve the technical problems of the existing liquid adding device with a relatively complex structure and poor accuracy.

[0005] To this end, according to one aspect of this application, a liquid injection device is provided, including:

[0006] A lifting mechanism;

[0007] A liquid filling mechanism, including a piston cylinder and a plunger slidably inserted into the piston cylinder. A stop portion is provided on the outer wall of the piston cylinder. The lower end of the piston cylinder is used to connect to a liquid storage tube. The upper end of the plunger is connected to the lifting mechanism and can drive the piston cylinder to move up and down together under the action of the lifting mechanism; and

[0008] A limiting member is arranged on the path of the downward movement of the stop portion. When the stop portion abuts against the limiting member, the piston cylinder is stationary relative to the limiting member, and the plunger can continue to move downward under the action of the lifting mechanism to push the reagent in the liquid storage tube outwards.

[0009] Optionally, the liquid injection device further includes a positioning seat, which is arranged below the liquid storage tube. The positioning seat is used to fix the kit. When the stop portion abuts against the limiting member, the lower end of the liquid storage tube is docked with the injection port of the kit.

[0010] Optionally, the liquid injection device further includes an elastic reset member disposed between the piston cylinder and the lifting mechanism, and the elastic reset member is used to reset the plunger in the piston cylinder.

[0011] Optionally, the elastic reset member includes a spring sleeved on the part of the plunger extending out of the piston cylinder, and two ends of the spring respectively abut against the upper end of the piston cylinder and the lifting mechanism.

[0012] Optionally, the limiting member includes a limiting plate provided with a through hole for the piston cylinder to pass through. A clamping groove is provided on the outer wall of the piston cylinder, and a clamping spring is clamped in the clamping groove, and the clamping spring forms the stopping portion.

[0013] Optionally, the lifting mechanism includes a lead screw motor, a guide rail and a slider. The lead screw of the lead screw motor and the guide rail are both arranged vertically. The slider is slidably connected to the guide rail and screwed to the lead screw of the lead screw motor. The slider moves up and down under the drive of the lead screw motor, and the upper end of the plunger is connected to the slider.

[0014] Optionally, the upper end of the piston cylinder is further provided with a guide rod extending vertically upward, and the slider is provided with a sliding hole slidably matched with the guide rod.

[0015] Optionally, the lower end of the piston cylinder is provided with a connector, and the upper end of the liquid storage pipe can be screwed or clamped to the connector.

[0016] According to another aspect of the present application, a liquid injection device is provided, including:

[0017] a carrier; and

[0018] a plurality of the above-mentioned liquid injection devices arranged side by side on the carrier.

[0019] Optionally, the carrier includes a bottom plate and a vertical plate provided on the bottom plate, and the lifting mechanism and the limiting member in the liquid injection device are installed on the vertical plate.

[0020] The beneficial effects of the liquid injection device and the liquid injection equipment provided by this application are as follows: Compared with the prior art, the liquid injection device of this application includes a lifting mechanism, a filling mechanism, and a limiting member, and has a simple structure. During use, a liquid storage tube storing a reagent is installed at the lower end of the piston cylinder, and a reagent kit to be filled is placed below the liquid storage tube. Then, the lifting mechanism is started, and the filling mechanism and the liquid storage tube move downward together under the drive of the lifting mechanism. When the stop portion on the outer wall of the piston cylinder abuts against the limiting member, the lower end of the liquid storage tube is docked with the injection port of the reagent kit. Then, the plunger of the filling mechanism continues to move downward under the action of the lifting mechanism, and the reagent in the liquid storage tube is injected into the reagent kit. The entire filling process only requires the lifting mechanism to drive the filling mechanism to move downward. Through the cooperation of the limiting member and the stop portion on the outer wall of the piston cylinder, positioning is achieved first and then liquid injection, greatly improving the filling accuracy. This liquid injection equipment has multiple independent liquid injection devices, which can not only fill multiple reagent kits simultaneously but also fill each reagent kit that needs to be filled individually, with a wider range of application scenarios. Moreover, it does not require a gas source, has a simple structure, and a relatively high liquid injection accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of this application. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0022] Among them:

[0023] Figure 1 is a schematic structural diagram of the liquid injection device shown in an embodiment of this application;

[0024] Figure 2 is a cross-sectional structural diagram of the liquid injection device shown in an embodiment of this application;

[0025] Figure 3 is a schematic structural diagram of the liquid injection equipment shown in an embodiment of this application;

[0026] Figure 4 is a schematic structural diagram of another liquid injection equipment shown in an embodiment of this application.

[0027] MAIN ELEMENT SYMBOL DESCRIPTION:

[0028] 1. Liquid storage tube; 2. Reagent kit;

[0029] 10. Liquid injection device; 20. Carrier; 21. Bottom plate; 22. Vertical plate; 30. Housing;

[0030] 100. Lifting mechanism; 110. Lead screw motor; 120. Guide rail; 130. Slide block;

[0031] 200, filling mechanism; 210, piston cylinder; 211, stopper; 212, guide rod; 213, connector; 220, plunger;

[0032] 300, limiter;

[0033] 400, positioning seat;

[0034] 500, elastic reset member;

[0035] 600. Filter. DETAILED DESCRIPTION

[0036] In order to facilitate the understanding of the present application, the present application will be described more comprehensively with reference to the relevant drawings below. The preferred embodiments of the present application are provided in the drawings. However, the present application can be implemented in many other different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure of the present application more thorough and comprehensive.

[0037] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.

[0038] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application. In the description of the present application, "plurality" means two or more, unless otherwise clearly and specifically defined.

[0039] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0040] It should also be noted that, in the embodiments of the present application, the same figure mark is used to represent the same component or the same part. For the same parts in the embodiments of the present application, the figure may only mark one of the parts or components as an example. It should be understood that the figure mark also applies to other identical parts or components.

[0041] According to one aspect of the present application, embodiments of the present application provide a liquid injection device. As Figure 1 shown, the liquid injection device 10 includes a lifting mechanism 100, a filling mechanism 200, and a limiting member 300. The filling mechanism 200 includes a piston cylinder 210 and a plunger 220 slidably inserted into the piston cylinder 210. A stop portion 211 is provided on the outer wall of the piston cylinder 210. The lower end of the piston cylinder 210 is used to connect to a liquid storage tube 1 (the liquid storage tube 1 is a consumable and stores a reagent inside). The upper end of the plunger 220 is connected to the lifting mechanism 100 and can drive the piston cylinder 210 to move up and down together under the action of the lifting mechanism 100. The limiting member 300 is arranged on the path of the downward movement of the stop portion 211. When the stop portion 211 abuts against the limiting member 300, the piston cylinder 210 is stationary relative to the limiting member 300, and the plunger 220 can continue to move downward under the action of the lifting mechanism 100 to push the reagent in the liquid storage tube 1 outwards.

[0042] In the embodiment of the present application, the liquid injection device 10 includes a lifting mechanism 100, a filling mechanism 200, and a limiting member 300, and has a simple structure. When in use, the liquid storage tube 1 storing the reagent is installed at the lower end of the piston cylinder 210, the reagent kit 2 to be filled is placed below the liquid storage tube 1, and then the lifting mechanism 100 is started. The filling mechanism 200 and the liquid storage tube 1 first move downward together under the drive of the lifting mechanism 100. When the stop portion 211 on the outer wall of the piston cylinder 210 abuts against the limiting member 300, the lower end of the liquid storage tube 1 is docked with the injection port of the reagent kit 2. Then, the plunger 220 of the filling mechanism 200 continues to move downward under the action of the lifting mechanism 100 to inject the reagent in the liquid storage tube 1 into the reagent kit 2. The entire filling process only requires the lifting mechanism 100 to drive the plunger 220 to move downward. Through the cooperation of the limiting member 300 and the stop portion 211 on the outer wall of the piston cylinder 210, positioning is first achieved and then liquid injection is performed, greatly improving the filling accuracy.

[0043] In one embodiment, as Figure 1 - Figure 2 shown, the liquid injection device 10 further includes a positioning seat 400. The positioning seat 400 is arranged below the liquid storage tube 1 and is used to fix the reagent kit 2. When the stop portion 211 abuts against the limiting member 300, the lower end of the liquid storage tube 1 is docked with the injection port of the reagent kit 2. By providing the positioning seat 400, it is convenient to position and fix the reagent kit 2 to be filled, further improving the accuracy of liquid injection.

[0044] In one embodiment, as Figure 1 - Figure 2 shown, the liquid injection device 10 further includes an elastic reset member 500. The elastic reset member 500 is arranged between the piston cylinder 210 and the lifting mechanism 100 and is used to reset the plunger 220 in the piston cylinder 210.

[0045] Understandably, after the stop portion 211 on the outer wall of the piston barrel 210 abuts against the limiting member 300, during the process that the plunger 220 and the lifting mechanism 100 continue to move downward to inject the reagent, the elastic reset member 500 is compressed. When the amount of the reagent injected into the reagent kit 2 reaches the target, the lifting mechanism 100 moves upward, and the elastic reset member 500 rebounds, driving the plunger 220 in the piston barrel 210 to reset, so as to facilitate the next injection by the injection mechanism 200.

[0046] Specifically, the elastic reset member 500 can adopt elastic members such as springs and reed pieces. Taking the elastic reset member 500 adopting a spring as an example, refer to Figure 1 and Figure 2 As shown, the spring is sleeved on the part of the plunger 220 extending out of the piston barrel 210, and both ends of the spring abut against the upper end of the piston barrel 210 and the lifting mechanism 100 respectively.

[0047] In one embodiment, as Figure 1 - Figure 2 shown, the limiting member 300 includes a limiting plate. A through hole for the piston barrel 210 to pass through is provided on the limiting plate. A clamping groove is provided on the outer wall of the piston barrel 210, and a snap spring is clamped in the clamping groove, and the snap spring forms the stop portion 211.

[0048] With this setting, through the cooperation of the snap spring on the outer wall of the piston barrel 210 and the limiting plate provided with the through hole, the stop of the piston barrel 210 after descending a certain height is realized, and the structure is simple and easy to implement. In addition, after the snap spring abuts against the limiting plate near the through hole, as the lifting mechanism 100 drives the plunger 220 to continue to move downward, the abutting force between the snap spring and the limiting plate acts on the whole circle of the snap spring, ensuring uniform force on the piston barrel 210.

[0049] It can be imagined that in other embodiments, the limiting member 300 can also adopt a limiting block, and the stop portion 211 can be a convex column or a convex flange integrally protruding from the outer wall of the piston barrel 210. The stop of the piston barrel 210 after descending a certain height is realized by the abutment of the convex column or the convex flange on the outer wall of the piston barrel 210 against the limiting block.

[0050] In one embodiment, as Figure 1 shown, the lifting mechanism 100 includes a lead screw motor 110, a guide rail 120 and a slider 130. The lead screw of the lead screw motor 110 and the guide rail 120 are both arranged vertically. The slider 130 is slidably connected to the guide rail 120 and screwed to the lead screw of the lead screw motor 110. The slider 130 moves up and down under the drive of the lead screw motor 110, and the upper end of the plunger 220 is connected to the slider 130.

[0051] The working principle of the lifting mechanism 100 is as follows: when the lead screw motor 110 is started, the lead screw rotates, driving the slider 130 screwed thereto to move up and down along the guide rail 120, and further driving the plunger 220 connected to the slider 130 to move up and down.

[0052] Due to the use of the lead screw and nut drive method, the motion accuracy is high, which is convenient for controlling the accuracy of the reagent injection volume. In addition, the lead screw motor 110 drives the slider 130 to slide up and down along the guide rail 120, and then drives the filling mechanism 200 connected to the slider 130 to move up and down, which can save space vertically and is conducive to the miniaturized design of the vertical dimension of the entire liquid injection device.

[0053] Furthermore, in order to improve the stability of the plunger 220 during the movement in the piston cylinder 210 and prevent relative rotation between the plunger 220 and the piston cylinder 210, a guide rod 212 extending vertically upward is provided at the upper end of the piston cylinder 210, and a sliding hole slidably matched with the guide rod 212 is provided on the slider 130. Through the cooperation of the guide rod 212 and the sliding hole on the slider 130, guidance is realized, and the movement of the plunger 220 relative to the piston cylinder 210 is improved to enhance the stability of the reagent injection process.

[0054] It can be conceived that in other embodiments, the lifting mechanism 100 can also adopt linear drive mechanisms such as a vertically arranged linear motor, an electric cylinder, a cylinder, etc.

[0055] In one embodiment, as Figure 1 and Figure 2 shown, a connection head 213 is provided at the lower end of the piston cylinder 210, and the upper end of the liquid storage tube 1 can be screwed or clamped to the connection head 213. Through the screwed or clamped connection method, it is convenient to quickly replace the liquid storage tube 1 after the reagent in the liquid storage tube 1 is injected each time.

[0056] In a specific embodiment, a filter 600 (such as a hydrophobic filter) is detachably provided in the connection head 213.

[0057] Taking the clamping between the liquid storage tube 1 and the connection head 213 as an example, when replacing the liquid storage tube 1, the filter 600 is inserted into the upper end inside the liquid storage tube 1, and then the upper end of the liquid storage tube 1 is inserted into the connection head 213 and rotated by a certain angle, and then positioned by a ball and rotated into the card slot of the connection head 213.

[0058] According to another aspect of the present application, an embodiment of the present application also provides a liquid injection device, as Figure 3 and Figure 4 shown, the liquid injection device includes a carrier 20 and a plurality of the liquid injection devices 10 in the above embodiments, and the plurality of liquid injection devices 10 are arranged side by side on the carrier 20.

[0059] Since the liquid injection device adopts the liquid injection device 10 in the above embodiment, correspondingly, it also has the advantages and benefits brought by the above liquid injection device 10. The multiple liquid injection devices 10 in this liquid injection device are independent of each other, and can not only realize liquid injection into multiple reagent kits 2 simultaneously, but also inject liquid into each reagent kit 2 that needs liquid injection separately. The application scenario is more extensive, and there is no need for a gas source, the structure is simple, and the liquid injection accuracy is relatively high.

[0060] In one embodiment, as Figure 3 shown, the carrier 20 includes a bottom plate 21 and a vertical plate 22 provided on the bottom plate 21. The lifting mechanism 100 and the limiting member 300 in the liquid injection device 10 are installed on the vertical plate 22, and the positioning seat 400 in the liquid injection device 10 is installed on the bottom plate 21.

[0061] Furthermore, in order to protect the lifting mechanism 100 in each liquid injection device 10, a cover 30 covering the lifting mechanism 100 of each liquid injection device 10 is also provided at the upper end of the vertical plate 22.

[0062] The technical features of the above embodiments can be combined arbitrarily. For the sake of concise description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope recorded in this specification.

[0063] The above embodiments only represent several implementation manners of the present application, and the description is relatively specific and detailed, but it should not be understood as a limitation to the scope of the application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present application, several deformations and improvements can still be made, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the appended claims.

Claims

1. A liquid injection device, characterized in that: include: Lifting mechanism (100); A filling mechanism (200) comprises a piston cylinder (210) and a plunger (220) slidably inserted in the piston cylinder (210); the outer wall of the piston cylinder (210) is provided with a stopper (211); the lower end of the piston cylinder (210) is used to connect to the liquid storage tube (1); the upper end of the plunger (220) is connected to the lifting mechanism (100) and can drive the piston cylinder (210) to move up and down together under the action of the lifting mechanism (100); and The limiting member (300) is arranged on the path of the stopping portion (211) moving downward. When the stopping portion (211) abuts against the limiting member (300), the piston cylinder (210) is stationary relative to the limiting member (300), and the plunger (220) can continue to move downward under the action of the lifting mechanism (100) to push the reagent in the liquid storage tube (1) outward.

2. The liquid injection device according to claim 1, characterized in that: The liquid injection device (10) further comprises a positioning seat (400), which is arranged below the liquid storage tube (1) and is used to fix the reagent box (2). When the stopper (211) abuts against the limiting member (300), the lower end of the liquid storage tube (1) is docked with the injection port of the reagent box (2).

3. The liquid injection device according to claim 1, characterized in that: The liquid injection device (10) further comprises an elastic reset member (500), wherein the elastic reset member (500) is arranged between the piston cylinder (210) and the lifting mechanism (100), and the elastic reset member (500) is used for resetting the plunger (220) in the piston cylinder (210).

4. The liquid injection device according to claim 3, characterized in that: The elastic return member (500) comprises a spring, which is sleeved on the portion of the plunger (220) extending out of the piston cylinder (210), and the two ends of the spring respectively abut against the upper end of the piston cylinder (210) and the lifting mechanism (100).

5. The liquid injection device according to claim 1, characterized in that: The limiting member (300) comprises a limiting plate, the limiting plate is provided with a through hole for the piston cylinder (210) to pass through, the outer wall of the piston cylinder (210) is provided with a clamping groove, a clamping spring is clamped in the clamping groove, and the clamping spring forms the stopper (211).

6. The liquid injection device according to claim 1, characterized in that: The lifting mechanism (100) comprises a screw motor (110), a guide rail (120) and a slider (130); the screw of the screw motor (110) and the guide rail (120) are both arranged vertically; the slider (130) is slidably connected to the guide rail (120) and is screwed to the screw of the screw motor (110); the slider (130) moves up and down under the drive of the screw motor (110); and the upper end of the plunger (220) is connected to the slider (130).

7. The liquid injection device according to claim 6, characterized in that: The upper end of the piston cylinder (210) is also provided with a guide rod (212) extending vertically upward, and the sliding block (130) is provided with a sliding hole that slidably cooperates with the guide rod (212).

8. The liquid injection device according to claim 1, characterized in that: The lower end of the piston cylinder (210) is provided with a connecting head (213), and the upper end of the liquid storage tube (1) can be screwed or clamped to the connecting head (213).

9. A liquid injection device, characterized in that: include: Carrier (20); as well as A plurality of liquid injection devices according to any one of claims 1 to 8, wherein the plurality of liquid injection devices (10) are arranged side by side on the carrier (20).

10. The liquid injection device according to claim 9, characterized in that: The carrier (20) comprises a bottom plate (21) and a vertical plate (22) arranged on the bottom plate (21); the lifting mechanism (100) and the limiting member (300) in the liquid injection device (10) are installed on the vertical plate (22).

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