Batch sample injector for antibody reagent

By designing an installation mechanism in the antibody reagent batch sample feeder to limit the collection box and the dropper plate, the problem of the inability to effectively limit the reagents to enter the dropper box accurately is solved, which improves the sample feeding effect and reduces reagent waste.

CN223042751UActive Publication Date: 2025-07-01WUHAN YUANGU BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422176691.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-04
Publication Date
2025-07-01
Estimated Expiration
2034-09-04

AI Technical Summary

Technical Problem

When used, existing antibody reagent batch sample feeders cannot effectively limit the liquid collection box and dropper box, resulting in the reagent being unable to enter the dropper box accurately, affecting the sample feeding effect and causing waste of reagents.

Method used

An antibody reagent batch sampler was designed, and the installation mechanism was used to limit the collection box and the dropper plate. The installation mechanism includes a fixing frame, cavity, screw rod, moving block, hinge rod, clamp rod and other components. The screw rod drives the moving block and hinge rod to move, and drives the clamp rod to snap into the limit slot to achieve limiting the dropper plate.

Benefits of technology

Through the design of the limiting mechanism, the stability and position accuracy of the dropper plate are ensured, the sample addition effect is improved, and the reagent waste is reduced.

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Abstract

The utility model relates to an antibody reagent batch sample injector which comprises a box body, two fixing frames are arranged at the bottom of an inner cavity of the box body, a collecting box and a dropper plate are arranged on the fixing frames, and mounting mechanisms are arranged in the fixing frames. And the mounting mechanism comprises a cavity formed in the fixing frames and limiting grooves formed in the opposite sides of the two fixing frames, and mounting blocks fixed to the collecting box are slidably connected into the limiting grooves. The device has the beneficial effects that the mounting block slides into the limiting groove, the screw rod is rotated, the screw rod drives the two moving blocks to move relatively at the same time, when the moving blocks move, the hinge rods are driven to rotate, the moving plates are driven to move through the hinge rods, and the clamping rods are driven to move together through the moving plates; the clamping rods are clamped into the first clamping grooves and the second clamping grooves respectively, the collecting box and the dropper plate are limited, deviation of the dropper plate in the using process is prevented, and the sample adding effect is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of antibody sample addition, and particularly relates to an antibody reagent batch sample addition device. Background Art

[0002] In the process of antibody tests in biopharmaceuticals, according to test requirements, sample addition of multiple specimens is required. Therefore, an antibody reagent batch sample addition device is needed.

[0003] For example, a Chinese patent (Publication No.: CN218107710U) discloses an antibody reagent batch sample addition device, which includes: a sample addition box body; support frames arranged at the lower parts of opposite side walls of the sample addition box body, respectively used for placing a dropper box and a liquid collection box; a sample addition container arranged on the sample addition box body; a liquid inlet main pipe communicating with the sample addition container, which is provided with a liquid inlet solenoid valve; a liquid outlet main pipe communicating with the sample addition container, which is provided with a liquid outlet solenoid valve and extends into the sample addition box body; and a liquid distribution branch pipe fixed in the sample addition box body, which communicates with the liquid outlet main pipe and is located above the dropper box. This utility model uses the liquid collection box as a prevention to collect the reagent that overflows due to excessive sample addition caused by operation errors and can be poured out in time, thus conveniently solving this problem.

[0004] For the above-mentioned antibody reagent batch sample addition device, during use, the liquid collection box can be first pushed into the sample addition box body, and then the dropper box can be inserted or removed. The liquid collection box is located below the dropper box. However, pushing the liquid collection box into the sample addition box body is not convenient for limiting the positions of the liquid collection box and the dropper box. As a result, during the use of the liquid collection box and the dropper box, the positions of the liquid collection box and the dropper box cannot be guaranteed, resulting in the liquid collection box and the dropper box not being completely located below the liquid distribution branch pipe, and a large amount of reagent cannot accurately enter the inside of the dropper box, affecting the effect of batch sample addition and causing waste of the reagent. Summary of the Utility Model

[0005] The purpose of the utility model is to provide an antibody reagent batch sample addition device to solve the above problems existing in the prior art.

[0006] The technical problem to be solved by the utility model is to provide an antibody reagent batch sample addition device.

[0007] The technical solution of the utility model to solve the above technical problems is as follows:

[0008] An antibody reagent batch sample addition device includes a box body. Two fixed frames are arranged at the bottom of the inner cavity of the box body. A collection box and a dropper plate are arranged on the fixed frames. An installation mechanism is arranged inside the fixed frames.

[0009] The installation mechanism includes a cavity opened inside the fixed frame and a limiting groove opened on the opposite side of the two fixed frames. An installation block fixed to the collection box is slidably connected inside the limiting groove. The back surface of the inner cavity of the cavity is rotatably connected by a bearing to a lead screw passing through the round hole of the fixed frame. The two ends of the lead screw have reverse threads, and both ends of the lead screw are threadedly connected with moving blocks. An articulated rod is hinged on the moving block. One side of the two articulated rods away from the moving block is hinged with a moving plate. A plurality of clamping rods are provided on the opposite sides of the two moving plates. A plurality of first clamping grooves are opened on the opposite sides of the two installation blocks. The lower clamping rods are slidably connected inside the first clamping grooves. The installation mechanism further includes a plurality of second clamping grooves opened on the left and right sides of the dropper plate. The upper clamping rods are slidably connected inside the second clamping grooves.

[0010] The beneficial effects of the present utility model are as follows: By sliding the installation block into the limiting groove and rotating the lead screw, the lead screw drives the two moving blocks to move relatively at the same time. When the moving blocks move, they will drive the articulated rods to rotate, and drive the moving plate to move through the articulated rods. The moving plate drives a plurality of clamping rods to move together, so that the clamping rods are respectively clamped into the first clamping grooves and the second clamping grooves to limit the collection box and the dropper plate, prevent deviation of the dropper plate during use, and improve the effect of sample addition.

[0011] On the basis of the above technical solutions, the present utility model can be further improved as follows.

[0012] Further, a rotating handle is fixed to one end of the lead screw located outside the fixed frame.

[0013] Further, two T-shaped sliders are fixed to the lower surface of the dropper plate, and T-shaped chutes are opened on the upper surface of the fixed frame. The T-shaped sliders are slidably connected inside the T-shaped chutes.

[0014] Further, the moving block is slidably connected to the inner wall of the cavity.

[0015] Further, a plurality of dropper boxes are provided on the top of the dropper plate, and a sampler body matching the plurality of dropper boxes is provided inside the box body. Description of the Drawings

[0016] Figure 1 is a schematic structural diagram of the present utility model;

[0017] Figure 2 is a schematic structural diagram of the installation mechanism of the present utility model;

[0018] Figure 3 is the present utility model Figure 1 The enlarged structural schematic diagram at A in.

[0019] In the drawings, the list of components represented by each reference numeral is as follows:

[0020] 1. Box body, 2. Fixed frame, 3. Installation mechanism, 301. Cavity, 302. Lead screw, 303. Moving block, 304. Hinge rod, 305. Moving plate, 306. Clamping rod, 307. Installation block, 308. Limiting groove, 309. First clamping groove, 310. Second clamping groove, 311. Rotating handle, 4. Collection box, 5. Dropper plate, 6. Dropper box, 7. Sampler body, 8. T-shaped slider, 9. T-shaped sliding groove. Specific implementation mode

[0021] The principles and features of the present utility model will be described below in conjunction with the accompanying drawings. The examples given are only used to explain the present utility model and are not intended to limit the scope of the present utility model.

[0022] As Figures 1 to 3 shown, Embodiment 1 of the present utility model is an antibody reagent batch sampler, which includes a box body 1. Two fixed frames 2 are provided at the bottom of the inner cavity of the box body 1. A collection box 4 and a dropper plate 5 are provided on the fixed frames 2. An installation mechanism 3 is provided inside the fixed frames 2. The collection box 4 and the dropper plate 5 are fixed by the installation mechanism 3, improving the stability of the collection box 4 and the dropper plate 5.

[0023] The installation mechanism 3 includes a cavity 301 opened inside the fixed frame 2 and a limiting groove 308 opened on the opposite sides of the two fixed frames 2. An installation block 307 fixed to the collection box 4 is slidably connected inside the limiting groove 308. The back of the inner cavity of the cavity 301 is rotatably connected by a bearing to a lead screw 302 passing through the round hole of the fixed frame 2. The two ends of the lead screw 302 are reverse threads. Both ends of the lead screw 302 are threadedly connected with moving blocks 303. By rotating the lead screw 302, the two moving blocks 303 are driven to move relatively or away from each other at the same time. Hinge rods 304 are hinged on the moving blocks 303. One side of the two hinge rods 304 away from the moving blocks 303 is hinged with a moving plate 305. A plurality of clamping rods 306 are provided on the opposite sides of the two moving plates 305. A plurality of first clamping grooves 309 are opened on the opposite sides of the two installation blocks 307. The lower clamping rods 306 are slidably connected inside the first clamping grooves 309. By clamping the clamping rods 306 inside the first clamping grooves 309, the collection box 4 is limited, improving the stability of the collection box 4. The installation mechanism 3 further includes a plurality of second clamping grooves 310 opened on the left and right sides of the dropper plate 5. The upper clamping rods 306 are slidably connected inside the second clamping grooves 310. By clamping the clamping rods 306 inside the second clamping grooves 310, the dropper plate 5 is limited, improving the stability of the dropper plate 5.

[0024] By sliding the installation block 307 into the interior of the limit slot 308 and rotating the lead screw 302, the lead screw 302 drives the two moving blocks 303 to move relatively simultaneously. When the moving blocks 303 move, they will drive the hinge rods 304 to rotate, and drive the moving plate 305 to move through the hinge rods 304. The moving plate 305 drives a plurality of clamping rods 306 to move together, so that the clamping rods 306 are respectively clamped into the interiors of the first clamping slot 309 and the second clamping slot 310, to limit the collection box 4 and the dropper plate 5, prevent deviation of the dropper plate 5 during use, and improve the effect of sample addition.

[0025] In this Embodiment 2 of an antibody reagent batch sampler, on the basis of Embodiment 1, a rotating handle 311 is fixed at one end of the lead screw 302 located outside the fixed frame 2, and the lead screw 302 is conveniently driven to rotate through the rotating handle 311.

[0026] In this Embodiment 3 of an antibody reagent batch sampler, on the basis of Embodiment 1, two T-shaped sliders 8 are fixed on the lower surface of the dropper plate 5, and a T-shaped sliding groove 9 is opened on the upper surface of the fixed frame 2. The T-shaped sliders 8 are slidably connected to the interior of the T-shaped sliding groove 9, which increases the stability of the dropper plate 5 during movement and limits it.

[0027] In this Embodiment 4 of an antibody reagent batch sampler, on the basis of Embodiment 1, the moving block 303 is slidably connected to the inner wall of the cavity 301, which increases the stability of the moving block 303 during movement.

[0028] In this Embodiment 5 of an antibody reagent batch sampler, on the basis of Embodiment 1, a plurality of dropper boxes 6 are provided on the top of the dropper plate 5, and a sampler body 7 matching the plurality of dropper boxes 6 is provided inside the box body 1. Through the plurality of dropper boxes 6, the reagents of the sampler body 7 are collected to achieve the purpose of batch sample addition.

[0029] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection scope of the present invention.

Claims

1. An antibody reagent batch injector, characterized in that: It comprises a box body (1), wherein two fixing frames (2) are provided at the bottom of the inner cavity of the box body (1), a collecting box (4) and a dropper plate (5) are provided on the fixing frames (2), and a mounting mechanism (3) is provided inside the fixing frames (2); The mounting mechanism (3) comprises a cavity (301) provided inside the fixing frame (2) and a limiting groove (308) provided on opposite sides of the two fixing frames (2); a mounting block (307) fixed to the collection box (4) is slidably connected inside the limiting groove (308); a screw rod (302) penetrating a circular hole of the fixing frame (2) is rotatably connected to the back of the inner cavity of the cavity (301) via a bearing; both ends of the screw rod (302) are reversely threaded; both ends of the screw rod (302) are threadedly connected to a moving block (303); and a hinge rod ( 304), a movable plate (305) is hingedly connected to one side of the two hinged rods (304) away from the movable block (303), a plurality of clamping rods (306) are provided on the opposite sides of the two movable plates (305), a plurality of first clamping grooves (309) are provided on the opposite sides of the two mounting blocks (307), the clamping rods (306) at the lower ends are slidably connected to the inside of the first clamping grooves (309), and the mounting mechanism (3) further comprises a plurality of second clamping grooves (310) provided on the left and right sides of the dropper plate (5), and the clamping rods (306) at the upper ends are slidably connected to the inside of the second clamping grooves (310).

2. The antibody reagent batch injector according to claim 1, characterized in that: A rotating handle (311) is fixed to one end of the screw rod (302) located outside the fixing frame (2).

3. The antibody reagent batch injector according to claim 1, characterized in that: Two T-shaped slide blocks (8) are fixed on the lower surface of the dropper plate (5), a T-shaped slide groove (9) is provided on the upper surface of the fixing frame (2), and the T-shaped slide block (8) is slidably connected to the inside of the T-shaped slide groove (9).

4. The antibody reagent batch injector according to claim 1, characterized in that: The moving block (303) is slidably connected to the inner wall of the cavity (301).

5. The antibody reagent batch injector according to claim 1, characterized in that: A plurality of dropper boxes (6) are arranged on the top of the dropper plate (5), and a sample injector body (7) matching the plurality of dropper boxes (6) is arranged inside the box body (1).

Citation Information

Patent Citations

  • Batch sample injector for antibody reagent

    CN218107710U