Sampling device for human stem cell research

Abstract

The utility model relates to the technical field of stem cell sampling, and discloses a sampling device based on human body stem cell research, which comprises a needle cylinder and a needle head fixedly mounted in the middle of one side of the needle cylinder, a piston is slidably mounted in an inner cavity of the needle cylinder, and a push-pull rod is fixedly mounted in the middle of one side of the piston. Through mutual cooperation of a connecting rod, a rectangular frame, a movable plate, a clamping ball, a fixed plate, a T-shaped pull rod and a reset spring, the circular plate can be clamped and fixed after moving to a certain position, discomfort of a patient caused by excessive force of a worker is prevented, the use effect of the device is improved, and the device is worthy of popularization and application. Through the arrangement of the sampling tube, continuous extraction and collection of stem cells can be realized, the sampling efficiency is improved, through the mutual cooperation of the fixing ring, the threaded rod, the knob, the threaded sleeve, the guide plate, the T-shaped guide rod, the circular ring, the sliding plate and the positioning rod, the sampling tube can be quickly mounted and dismounted, a new sampling tube can be conveniently replaced, and the sampling efficiency is improved. The operation is convenient.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell sampling, in particular to a sampling device for human stem cell research. Background Technique

[0002] Stem cells are a class of pluripotent cells with self-renewal and self-replication abilities. Stem cells can be divided into embryonic stem cells and adult stem cells, and can be classified into totipotent stem cells, pluripotent stem cells, and unipotent stem cells according to different differentiation potentials. They have characteristics such as multi-directional differentiation potential, infinite division, and proliferation. The technical research of stem cells requires sampling of samples.

[0003] When the existing sampling device for human stem cell research is in use, it can usually achieve the extraction of stem cells. However, after the stem cells are aspirated, they need to be stored immediately, and the existing one cannot achieve continuous extraction and collection of stem cells, with low sampling efficiency and poor use effect.

[0004] Therefore, we propose a sampling device for human stem cell research to solve the problems raised above. Summary of the Invention

[0005] The purpose of the utility model is to provide a sampling device for human stem cell research to solve the problems raised in the above background technique.

[0006] To achieve the above purpose, the utility model provides the following technical scheme: A sampling device for human stem cell research, including a syringe barrel and a needle head fixedly installed in the middle of one side of the syringe barrel. A piston is slidably installed in the inner cavity of the syringe barrel. A push rod is fixedly installed in the middle of one side of the piston, and one end of the push rod extends out of the syringe barrel through the side wall of the syringe barrel in a movable manner. A circular plate is fixedly installed at one end of the push rod. A clamping component is installed at the rear side of the other side of the syringe barrel, and a sampling tube is movably installed through the side wall of the bottom of the syringe barrel. A fixing component is installed on one side of the syringe barrel.

[0007] The fixing component includes fixing rings fixedly installed on both sides of one side of the syringe barrel, and threaded rods movably installed respectively under the rear sides of the inner sides of the fixing rings. The inner ends of the threaded rods are fixedly installed with a transmission rod together. A knob is fixedly sleeved on the output shaft of the transmission rod, and threaded sleeves are respectively threadedly installed on the output shafts of the threaded rods. A circular ring is jointly arranged inside the threaded sleeves. The circular ring is fixedly sleeved on the sampling tube. Through holes are respectively opened on both sides of the circular ring, and sliding plates are respectively slidably installed through the top sides of both sides of the circular ring. The tops of the sliding plates are respectively fixedly installed on the syringe barrel. Positioning grooves corresponding to the through holes are respectively opened on the outer sides of the sliding plates. Positioning rods are respectively inserted into the inner cavities of the positioning grooves, and the outer ends of the positioning rods respectively pass through the through holes and extend to the outer sides of the circular ring. The outer ends of the positioning rods are respectively fixedly installed on the threaded sleeves.

[0008] Preferably, guide plates are fixedly installed at the tops of the threaded sleeves respectively, and T-shaped guide rods are slidably installed through the guide plates respectively, and the outer ends of the T-shaped guide rods are fixedly installed on the fixed rings.

[0009] Preferably, a slot is formed in the middle of the rear side of the circular plate.

[0010] Preferably, the clamping assembly includes a connecting rod fixedly installed on the rear side of the other side of the syringe barrel and a rectangular frame fixedly installed at one end of the connecting rod. A moving plate is arranged on the front side of the inner cavity of the rectangular frame, and a fixed rod is fixedly installed in the middle of the front side of the moving plate. A clamping ball is fixedly installed at the front end of the fixed rod. A fixing plate is arranged on the rear side of the moving plate, and the front side of the fixing plate is fixedly installed on the rectangular frame. A T-shaped pull rod is slidably installed through the fixing plate, and the front end of the T-shaped pull rod is fixedly installed on the moving plate.

[0011] Preferably, a return spring is sleeved on the output shaft of the T-shaped pull rod, and both ends of the return spring are fixedly installed on the moving plate and the fixing plate respectively.

[0012] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0013] 1. Through the mutual cooperation among components such as the connecting rod, the rectangular frame, the moving plate, the clamping ball, the fixing plate, the T-shaped pull rod and the return spring, the circular plate can be clamped and fixed after moving to a certain position, preventing discomfort of the patient caused by excessive force of the staff, and improving the use effect of the device.

[0014] 2. Through the arrangement of the sampling tube, continuous extraction and collection of stem cells can be realized, improving the sampling efficiency. And through the mutual cooperation among components such as the fixed ring, the threaded rod, the knob, the threaded sleeve, the guide plate, the T-shaped guide rod, the circular ring, the sliding plate and the positioning rod, the installation and disassembly of the sampling tube can be quickly realized, which is beneficial to replacing a new sampling tube, and the operation is convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is the overall three-dimensional view of the present utility model;

[0016] Figure 2 is the partial right-side view sectional three-dimensional view of the present utility model;

[0017] Figure 3 is the bottom three-dimensional view of the present utility model;

[0018] Figure 4 is the partial structural three-dimensional view of the piston of the present utility model;

[0019] Figure 5 is the Figure 4 enlarged view at A of the present utility model;

[0020] Figure 6 It is a three-dimensional view of the partial structure of the sampling tube of the present utility model;

[0021] Figure 7 It is a three-dimensional view of the partial structure of the fixing ring of the present utility model;

[0022] Figure 8 It is a three-dimensional view of the partial bottom-up cross-section of the present utility model.

[0023] In the figure: 1, syringe; 2, needle; 3, piston; 4, push-pull rod; 5, circular plate; 51, slot; 6, clamping component; 61, connecting rod; 62, rectangular frame; 63, moving plate; 64, clamping ball; 65, fixing plate; 66, T-shaped pull rod; 661, return spring; 7, sampling tube; 8, fixing component; 81, fixing ring; 82, threaded rod; 83, knob; 84, threaded sleeve; 841, guide plate; 842, T-shaped guide rod; 85, circular ring; 86, sliding plate; 87, positioning rod. Specific embodiments

[0024] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0025] Embodiment 1: Please refer to Figures 1-8 , for a sampling device for human stem cell research, including a syringe 1 and a needle 2 fixedly installed in the middle of one side of the syringe 1. A piston 3 is slidably installed in the inner cavity of the syringe 1. The middle of one side of the piston 3 is fixedly installed with a push-pull rod 4, and one end of the push-pull rod 4 extends through the outside of the syringe 1 movably. One end of the push-pull rod 4 is fixedly installed with a circular plate 5. A clamping component 6 is installed on the rear side of the other side of the syringe 1, and a sampling tube 7 is movably installed through one side of the bottom of the syringe 1. A fixing component 8 is installed on one side of the outside of the syringe 1. Through the setting of the clamping component 6, the circular plate 5 can be limited, and through the setting of the fixing component 8, the sampling tube 7 can be installed and disassembled.

[0026] The fixing component 8 includes fixing rings 81 fixedly installed on one side and both sides of the outer side of the syringe barrel 1, and threaded rods 82 respectively movably installed under the rear side of the inner side of the fixing rings 81. The inner ends of the threaded rods 82 are fixedly installed with a transmission rod together. A knob 83 is fixedly sleeved on the output shaft of the transmission rod, and threaded sleeves 84 are respectively threadedly installed on the output shafts of the threaded rods 82. A circular ring 85 is jointly arranged inside the threaded sleeves 84. The circular ring 85 is fixedly sleeved on the sampling tube 7. Through holes are respectively opened on both sides of the circular ring 85, and sliding plates 86 are respectively slidably penetrated and installed on both sides of the top of the circular ring 85. The tops of the sliding plates 86 are respectively fixedly installed on the syringe barrel 1. Positioning grooves corresponding to the through holes are respectively opened on the outer sides of the sliding plates 86. Positioning rods 87 are respectively inserted into the inner cavities of the positioning grooves, and the outer ends of the positioning rods 87 respectively pass through the through holes and extend to the outer sides of the circular ring 85. The outer ends of the positioning rods 87 are respectively fixedly installed on the threaded sleeves 84, which can realize the installation, disassembly and replacement of the sampling tube 7, and the operation is convenient.

[0027] Guide plates 841 are respectively fixedly installed on the tops of the threaded sleeves 84, and T-shaped guide rods 842 are respectively slidably penetrated and installed on the guide plates 841. The outer ends of the T-shaped guide rods 842 are respectively fixedly installed on the fixing rings 81, which play a role of guiding and limiting.

[0028] A slot 51 is opened in the middle of the rear side of the circular plate 5, which is conducive to the development of the limiting work of the circular plate 5.

[0029] In this embodiment: when in use, insert the needle 2 into the part where the stem cells are to be extracted, pull the circular plate 5 to move. When the circular plate 5 moves, it will drive the piston 3 to move in the inner cavity of the syringe barrel 1 through the push rod 4. The liquid containing stem cells can enter the syringe barrel 1 and enter the sampling tube 7 for collection through the increased pressure. After the liquid in one sampling tube 7 reaches a certain amount, remove the sampling tube 7, and then replace it with a new sampling tube 7. Rotate the knob 83 to drive the transmission rod to rotate. The rotation of the transmission rod will drive the threaded rods 82 on both sides to rotate. When the threaded rods 82 rotate, they will drive the threaded sleeves 84 to move in the opposite direction. When the threaded sleeves 84 move in the opposite direction, the positioning rods 87 will move in the opposite direction and respectively move away from the inner cavities of the adjacent positioning grooves. At this time, the disassembly of the sampling tube 7 can be released, and vice versa, the new sampling tube 7 can be installed and fixed.

[0030] Embodiment 2: This embodiment is an improvement made on the basis of Embodiment 1. Specifically, please refer to Figures 1-3, the clamping component 6 includes a connecting rod 61 fixedly installed on the rear side of the other side of the syringe barrel 1 and a rectangular frame 62 fixedly installed at one end of the connecting rod 61. A moving plate 63 is arranged on the front side of the inner cavity of the rectangular frame 62, and a fixing rod is fixedly installed in the middle of the front side of the moving plate 63. A clamping ball 64 is fixedly installed at the front end of the fixing rod. A fixing plate 65 is arranged on the rear side of the moving plate 63, and the front side of the fixing plate 65 is fixedly installed on the rectangular frame 62. A T-shaped pull rod 66 is slidably installed through the fixing plate 65 in a penetrating manner, and the front end of the T-shaped pull rod 66 is fixedly installed on the moving plate 63, which plays a role in clamping and limiting the circular plate 5 after it moves a certain distance, preventing it from continuing to move and preventing excessive force.

[0031] A return spring 661 is sleeved on the output shaft of the T-shaped pull rod 66, and both ends of the return spring 661 are fixedly installed on the moving plate 63 and the fixing plate 65 respectively, which plays a role in the movement and restoration of the T-shaped pull rod 66.

[0032] In this embodiment: when the circular plate 5 is pulled and moved to a certain position, it will be in contact with the clamping ball 64 and squeeze it to move backward. When the clamping ball 64 moves backward, it will drive the moving plate 63 to move backward and squeeze the return spring 661. When the circular plate 5 continues to move, the clamping ball 64 will be inserted into the inner cavity of the slot 51 under the action of the return spring 661, which plays a role in restricting the continuous movement of the circular plate 5. The staff can release the pull on the T-shaped pull rod 66.

[0033] Working principle: When in use, insert the needle 2 into the part where the stem cells are to be extracted, pull the circular plate 5 to move. When the circular plate 5 moves, it will drive the piston 3 to move in the inner cavity of the syringe barrel 1 through the push rod 4. By increasing the pressure, the liquid containing stem cells can enter the syringe barrel 1 and then enter the sampling tube 7 for collection. After the liquid in one sampling tube 7 reaches a certain amount, remove the sampling tube 7, and then replace it with a new sampling tube 7. Rotate the knob 83 to drive the transmission rod to rotate. When the transmission rod rotates, it will drive the threaded rods 82 on both sides to rotate. When the threaded rods 82 rotate, they will drive the threaded sleeves 84 to move in the opposite direction. When the threaded sleeves 84 move in the opposite direction, the positioning rods 87 will move in the opposite direction and respectively move away from the inner cavity of the adjacent positioning grooves. At this time, the disassembly of the sampling tube 7 can be released. On the contrary, the new sampling tube 7 can be installed and fixed. When the circular plate 5 is pulled and moved to a certain position, it will be in contact with the clamping ball 64 and squeeze it to move backward. When the clamping ball 64 moves backward, it will drive the moving plate 63 to move backward and squeeze the return spring 661. When the circular plate 5 continues to move, the clamping ball 64 will be inserted into the inner cavity of the slot 51 under the action of the return spring 661, which plays a role in restricting the continuous movement of the circular plate 5. The staff can release the pull on the T-shaped pull rod 66.

[0034] The content not described in detail in this specification belongs to the prior art well-known to those skilled in the art.

[0035] Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A sampling device for human stem cell research, comprising a syringe (1) and a needle (2) fixedly installed in the middle of one side of the syringe (1), characterized in that: A piston (3) is slidably installed in the inner cavity of the syringe barrel (1). In the middle of one side of the piston (3), a push-pull rod (4) is fixedly installed, and one end of the push-pull rod (4) extends out of the syringe barrel (1) through the movable connection. A circular plate (5) is fixedly installed at one end of the push-pull rod (4). A clamping component (6) is installed at the rear side of the other side of the syringe barrel (1), and a sampling tube (7) is movably installed through one side of the bottom of the syringe barrel (1). A fixing component (8) is installed on one side of the outer side of the syringe barrel (1); The fixing component (8) includes fixing rings (81) fixedly installed on both sides of one side of the outer side of the syringe barrel (1), and threaded rods (82) respectively movably installed at the rear side below the inner sides of the fixing rings (81). The inner ends of the threaded rods (82) are fixedly installed with a transmission rod together. A knob (83) is fixedly sleeved on the output shaft of the transmission rod, and threaded sleeves (84) are respectively threadedly installed on the output shafts of the threaded rods (82). A circular ring (85) is jointly arranged inside the threaded sleeves (84). The circular ring (85) is fixedly sleeved on the sampling tube (7). Through holes are respectively opened on both sides of the circular ring (85), and sliding plates (86) are respectively slidably installed through the top sides of the circular ring (85). The tops of the sliding plates (86) are respectively fixedly installed on the syringe barrel (1). Positioning grooves corresponding to the through holes are respectively opened on the outer sides of the sliding plates (86). Positioning rods (87) are respectively inserted into the inner cavities of the positioning grooves, and the outer ends of the positioning rods (87) respectively pass through the through holes and extend to the outer sides of the circular ring (85). The outer ends of the positioning rods (87) are respectively fixedly installed on the threaded sleeves (84).

2. The sampling device for human stem cell research according to claim 1, characterized in that: Guide plates (841) are respectively fixedly installed on the tops of the threaded sleeves (84), and T-shaped guide rods (842) are respectively slidably installed through the guide plates (841). The outer ends of the T-shaped guide rods (842) are respectively fixedly installed on the fixing rings (81).

3. The sampling device for human stem cell research according to claim 1, characterized in that: A slot (51) is opened in the middle of the rear side of the circular plate (5).

4. The sampling device for human stem cell research according to claim 1, characterized in that: The clamping component (6) includes a connecting rod (61) fixedly installed at the rear side of the other side of the syringe barrel (1) and a rectangular frame (62) fixedly installed at one end of the connecting rod (61). A moving plate (63) is arranged at the front side inside the rectangular frame (62). A fixing rod is fixedly installed in the middle of the front side of the moving plate (63). A clamping ball (64) is fixedly installed at the front end of the fixing rod. A fixing plate (65) is arranged at the rear side of the moving plate (63), and the front side of the fixing plate (65) is fixedly installed on the rectangular frame (62). A T-shaped pull rod (66) is slidably installed through the fixing plate (65). The front end of the T-shaped pull rod (66) is fixedly installed on the moving plate (63).

5. The sampling device for human stem cell research according to claim 4, wherein: A return spring (661) is sleeved on the output shaft of the T-shaped pull rod (66), and both ends of the return spring (661) are respectively fixedly installed on the moving plate (63) and the fixing plate (65).

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