Industrial stainless steel jacket chromatographic column

Abstract

The utility model discloses an industrial stainless steel jacket chromatographic column, and particularly relates to the field of chromatographic columns, the industrial stainless steel jacket chromatographic column comprises a bottom plate, a plurality of supporting legs are arranged at the bottom of the bottom plate, a sealing plug is fixedly connected to the middle of the bottom plate, a plurality of positioning blocks and stabilizing rods are fixedly connected to the top of the bottom plate, and a bottom column is arranged at the top of the bottom plate. And the bottom of the bottom column is fixedly connected with a connecting bottom plate. According to the utility model, the top column and the bottom column are connected through the thread bushing and are convenient to combine, disassemble and use, so that sectional disassembly and internal filler replacement are convenient, the bottom column can be conveniently separated from the bottom plate, the filler in the middle of the bottom column can be conveniently cleaned, and the middle parts of the bottom column and the top column can be cleaned and used; combined mounting and dismounting cleaning use are achieved, the use effect is improved, and the connecting sealing strength of the bottom column and the top column can be improved by inserting the connecting ring into the connecting groove.

Description

Technical Field

[0001] The utility model relates to the technical field of chromatography columns, and more specifically, to an industrialized stainless steel jacketed chromatography column. Background Art

[0002] Chromatographic columns are widely used as separation and purification equipment in the preparation of high-purity pharmaceutical intermediates. Chromatographic columns are the main body of gel chromatography technology. They are generally made of glass tubes or organic glass tubes. They are a type of chromatography that separates components in a sample mixture according to their different distribution coefficients in the stationary phase and the mobile phase. Jacketed chromatography columns are one type of them. Stainless steel jacketed chromatography columns are stainless steel chromatography columns used in industry.

[0003] Most of the existing stainless steel jacketed chromatography columns are of an integrated column structure, which are fixed by multiple screws at both ends. When the chromatography column is in use, the material is first loaded into the column. After the material settles, the pressure plate is driven downward by the rotary handle to compact the material. Therefore, the column is an integrated structure and cannot be disassembled in sections, which makes it difficult to replace the filler and to clean the inside of the stainless steel chromatography column, which brings certain inconveniences to the later use. Therefore, an industrial stainless steel jacketed chromatography column is proposed. Utility Model Content

[0004] In order to overcome the above defects of the prior art, the utility model provides an industrial stainless steel jacketed chromatography column to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an industrial stainless steel jacketed chromatography column, comprising a bottom plate, a plurality of supporting legs are arranged at the bottom of the bottom plate, a sealing plug is fixedly connected to the middle of the bottom plate, a plurality of positioning blocks and a stabilizing rod are fixedly connected to the top of the bottom plate, a bottom column is arranged at the top of the bottom plate, a connecting bottom plate is fixedly connected to the bottom of the bottom column, and positioning sockets are opened around the connecting bottom plate;

[0006] The top of the bottom column is fixedly connected with a connecting ring, the top fixed sleeve of the bottom column is provided with a first limiting ring, the outer sleeve of the first limiting ring is provided with a threaded sleeve, the bottom of the inner cavity of the threaded sleeve is fixedly connected with a second limiting ring, and the outer surface of the threaded sleeve is fixedly connected with a first toggle plate;

[0007] A top column is arranged on the top of the bottom column, a second toggle plate is fixedly connected to the bottom outer surface of the top column, a top plate is fixedly connected to the top of the top column, a top plate is arranged on the top of the top plate, a top plug is fixedly connected to the middle of the top plate, and a threaded rod is inserted in the middle of the top plug.

[0008] Preferably, the cross-sectional shape of the support leg is set to be "Z"-shaped, the top of the support leg is fixedly connected with a screw rod, the screw rod passes through the wall of the base plate and is sleeved with a hexagonal nut, and the bottom end of the support leg is provided with a mounting hole.

[0009] Preferably, the top end of the sealing plug extends to the inside of the bottom column and is matched with the inner cavity of the bottom column, the positioning hole corresponds to the positioning block, and the positioning block passes through the middle of the positioning hole.

[0010] Preferably, the bottom column and the top column are both arranged between three stabilizing rods, and a connecting groove is opened in the bottom inner cavity of the top column, and the connecting groove is adapted to a connecting ring, and the connecting ring is arranged in the middle of the connecting groove.

[0011] Preferably, the second limiting ring is arranged at the bottom of the first limiting ring, the outer surface diameter of the bottom end of the top column is adapted to the inner cavity diameter of the threaded sleeve, and the top end of the threaded sleeve is sleeved on the bottom end of the top column and threadedly connected to the outer surface of the bottom end of the top column.

[0012] Preferably, the number of the second toggle plates and the first toggle plates is set to be multiple, the stabilizing rod passes through the middle of the top plate and is sleeved with a nut, the top plug is adapted to the top inner cavity of the top column, and the bottom end of the top plug extends to the inside of the top column.

[0013] Preferably, the threaded rod is threadedly connected to the top plug, the top of the threaded rod is fixedly connected to a turntable, the middle of the turntable is provided with a through pipe, the bottom of the threaded rod is rotatably connected to a pressure plate, and a sealing gasket is provided on the outer surface of the pressure plate.

[0014] Technical effects and advantages of the utility model:

[0015] 1. The utility model firstly connects the top column and the bottom column through the threaded sleeve, which is convenient for assembly and disassembly, so as to facilitate segmented disassembly and replacement of internal fillers. At the same time, the bottom column can be easily separated from the bottom plate, and the fillers in the middle of the bottom column can be easily cleaned, and the middle of the bottom column and the top column can be cleaned for use, so as to realize combined assembly and disassembly and cleaning, and improve the use effect. In addition, the connection ring is inserted into the interior of the connection groove, which can improve the connection sealing strength of the bottom column and the top column.

[0016] 2. The utility model is also connected to the bottom plate by the support legs, which is convenient for moving the bottom plate, and universal wheels or support plates can be installed at the bottom of the support legs to move and stably support the bottom plate, and the top plate is limited by the stabilizing rod, the installation of the bottom column is positioned by the positioning jack and the positioning block, and the bottom end of the bottom column is blocked by the sealing plug, and the top end of the top column is blocked by the top plug, so as to form a complete chromatography column, which is convenient for combined use;

[0017] In summary, through the mutual influence of the above-mentioned multiple functions, it is convenient to combine and disassemble for use, thereby facilitating segmented dismantling, and the internal filler can be replaced and cleaned at the same time, thereby improving the use effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0019] Figure 2 It is a schematic diagram of the cross-sectional structure of the utility model.

[0020] Figure 3 It is a schematic diagram of the explosion structure of the utility model.

[0021] Figure 4 It is a schematic diagram of the disassembled structure of the bottom plate, bottom column and threaded sleeve of the utility model.

[0022] Figure 5 It is a structural schematic diagram of the top column of the utility model.

[0023] The accompanying drawings are marked as follows: 1. base plate; 2. supporting leg; 3. sealing plug; 4. positioning block; 5. stabilizing rod; 6. base column; 7. connecting base plate; 8. positioning socket; 9. first limiting ring; 10. connecting ring; 11. threaded sleeve; 12. second limiting ring; 13. first toggle plate; 14. top column; 15. top plate; 16. second toggle plate; 17. connecting groove; 18. top plate; 19. top plug; 20. threaded rod; 21. turntable; 22. nut; 23. screw. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] As attached Figures 1-5The industrial stainless steel jacketed chromatography column shown comprises a bottom plate 1, a plurality of supporting legs 2 are arranged at the bottom of the bottom plate 1 to support the bottom plate 1, and movable wheels or anti-skid supporting plates can be installed at the bottom of the supporting legs 2 as needed, so as to stably support the bottom plate 1, a sealing plug 3 is fixedly connected to the middle of the bottom plate 1, and the bottom of the top chromatography column is conveniently blocked by the sealing plug 3, a plurality of positioning blocks 4 and a stabilizing rod 5 are fixedly connected to the top of the bottom plate 1, and the positioning blocks 4 are conveniently connected to the bottom column 6 for positioning and connection, and the stabilizing rod 5 is used to protect the bottom column 6 and limit the position at the same time, a bottom column 6 is arranged at the top of the bottom plate 1, and a connecting bottom plate 7 is fixedly connected to the bottom of the bottom column 6, and positioning holes 8 are opened around the connecting bottom plate 7, and the installation of the bottom column 6 can be fixed and limited by cooperating with the connecting bottom plate 7, the positioning holes 8 and the positioning blocks 4, and the blocking effect is achieved to prevent the bottom column 6 from rotating;

[0026] The top of the bottom column 6 is fixedly connected with a connecting ring 10, the top of the bottom column 6 is fixedly sleeved with a first limiting ring 9, the outer sleeve of the first limiting ring 9 is sleeved with a threaded sleeve 11, the bottom of the inner cavity of the threaded sleeve 11 is fixedly connected with a second limiting ring 12, and the outer surface of the threaded sleeve 11 is fixedly connected with a first toggle plate 13, the threaded sleeve 11 can be driven to rotate by rotating the first toggle plate 13, and the threaded sleeve 11 is limited by the cooperation of the first limiting ring 9 and the second limiting ring 12, so as to facilitate connection and use;

[0027] A top column 14 is provided at the top of the bottom column 6, and a second toggle plate 16 is fixedly connected to the bottom outer surface of the top column 14, and a top plate 15 is fixedly connected to the top of the top column 14. A top plate 18 is provided on the top of the top plate 15, and a top plug 19 is fixedly connected to the middle of the top plate 18. A threaded rod 20 is inserted in the middle of the top plug 19. The top column 14 and the bottom column 6 can be disassembled and connected for use, which is convenient for cleaning the internal pressing material after disassembly, and convenient for disassembly, cleaning and combined use. Through the cooperation of the connecting groove 17 and the connecting ring 10, the sealing effect of the connection between the threaded sleeve 11 and the bottom column 6 is improved, and the second toggle plate 16 is used to facilitate the limiting and fixing of the top column 14, and through the cooperation of the top plate 18 and the top plug 19, the top end of the top column 14 can be blocked and the top plate 18 can be limited and fixed by the stabilizing rod 5.

[0028] As attached Figures 1-4 As shown, the cross-sectional shape of the support leg 2 is set to be "Z"-shaped, and a screw 23 is fixedly connected to the top of the support leg 2. The screw 23 passes through the wall of the base plate 1 and is sleeved with a hexagonal nut. A mounting hole is set at the bottom end of the support leg 2, which is convenient for the support leg 2 to be combined and connected with the base plate 1. At the same time, it is convenient to install moving wheels or an anti-slip chassis at the bottom of the support leg 2 as needed, which is convenient for installation and use and improves the flexibility of use.

[0029] As attached Figures 2-4As shown, the top end of the plug 3 extends into the interior of the bottom column 6 and is adapted to the inner cavity of the bottom column 6. The positioning jack 8 corresponds to the positioning block 4. The positioning block 4 penetrates through the middle of the positioning jack 8. The bottom end of the bottom column 6 is blocked by the plug 3, and through the cooperation of the positioning jack 8 and the positioning block 4, it is convenient to position the bottom column 6, and it is convenient to disassemble, clean and use by combining and splitting.

[0030] As shown in the attached Figures 1-5 As shown, both the bottom column 6 and the top column 14 are arranged between the three stabilizing rods 5. A connecting groove 17 is provided in the inner cavity at the bottom of the top column 14. The connecting groove 17 is adapted to the connecting ring 10. The connecting ring 10 is arranged in the middle of the connecting groove 17. The bottom column 6 and the top column 14 are limited and protected by the stabilizing rods 5, and through the cooperation of the connecting groove 17 and the connecting ring 10, the connection and sealing strength between the bottom column 6 and the top column 14 is improved, and the use effect is improved.

[0031] As shown in Attachments 1-4, the second limiting ring 12 is arranged at the bottom of the first limiting ring 9. The outer diameter of the bottom end surface of the top column 14 is adapted to the inner diameter of the threaded sleeve 11. The top end of the threaded sleeve 11 is sleeved on the bottom end of the top column 14 and is threadedly connected to the outer surface of the bottom end of the top column 14. The threaded sleeve 11 is limited by the first limiting ring 9 and the second limiting ring 12, so that when the threaded sleeve 11 is threadedly connected to the bottom end of the top column 14, the connecting ring 10 is tightly and fixedly connected to the connecting groove 17, which is convenient for connection and use.

[0032] As shown in the attached Figures 1-4 As shown, the number of the second toggle plates 16 and the first toggle plates 13 is set to be multiple. The stabilizing rod 5 penetrates through the middle of the top plate 18 and is sleeved with a nut 22. The top plug 19 is adapted to the inner cavity at the top end of the top column 14. The bottom end of the top plug 19 extends into the interior of the top column 14. Through the cooperation of the second toggle plate 16 and the first toggle plate 13, it is convenient to rotate the threaded sleeve 11, and it is convenient to connect the top column 14 and the threaded sleeve 11. And through the nut 22, the top plate 18 can be extruded, so as to control the top plug 19 to extrude and seal the top of the top column 14, and further improve the sealing connection strength of the multi-structure.

[0033] As shown in the attached Figures 1-3 As shown, the threaded rod 20 is threadedly connected to the top plug 19. A turntable 21 is fixedly connected to the top of the threaded rod 20. A through pipe is arranged in the middle of the turntable 21. The bottom of the threaded rod 20 is rotatably connected to a pressing plate. A sealing gasket is arranged on the outer surface of the pressing plate. By rotating the turntable 21, the threaded rod 20 is controlled to drive the pressing plate to move up and down, which is convenient for pressing materials.

[0034] Working principle of the utility model: When in use, only need to penetrate the screw rod 23 through the bottom plate 1 to fix the supporting leg 2 at the bottom of the bottom plate 1, then place the bottom column 6 on the top of the bottom plate 1, and make the positioning block 4 penetrate through the middle of the positioning jack 8 to position the bottom column 6. At the same time, block the bottom end of the bottom column 6 with the plug 3;

[0035] Then place the top column 14 on the top of the bottom column 6, insert the connecting ring 10 into the inside of the connecting groove 17, and then rotate the threaded sleeve 11 to make the threaded sleeve 11 sleeve on the bottom end of the top column 14 and be threadedly connected with the top column 14 until the connecting ring 10 squeezes the inner cavity top wall of the connecting groove 17 to improve the connection strength between the bottom column 6 and the top column 14;

[0036] Then move the top plate 18 to block the top end of the top column 14 with the top plug 19. At the same time, move the pressure plate to the middle of the top column 14, and then limit the top plate 18 through the stabilizing rod 5. At the same time, rotate the nut 22 to squeeze the top plate 18, which is convenient for blocking the top end of the top column 14, convenient for assembly and use, and convenient for disassembling and cleaning the internal pressing material, improving the use effect.

[0037] The above are only the preferred embodiments of the present utility model and are not used to limit the present utility model. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included in the protection scope of the present utility model.

Claims

1. Industrialized stainless steel jacket chromatography column, including a bottom plate (1), characterized in that: A plurality of supporting legs (2) are arranged at the bottom of the base plate (1), a sealing plug (3) is fixedly connected to the middle of the base plate (1), a plurality of positioning blocks (4) and a stabilizing rod (5) are fixedly connected to the top of the base plate (1), a bottom column (6) is arranged at the top of the base plate (1), a connecting base plate (7) is fixedly connected to the bottom of the bottom column (6), and positioning holes (8) are arranged around the connecting base plate (7); The top of the base column (6) is fixedly connected with a connecting ring (10), the top of the base column (6) is fixedly sleeved with a first limiting ring (9), the outer portion of the first limiting ring (9) is sleeved with a threaded sleeve (11), the inner bottom of the threaded sleeve (11) is fixedly connected with a second limiting ring (12), and the outer surface of the threaded sleeve (11) is fixedly connected with a first toggle plate (13); A top column (14) is arranged on the top of the bottom column (6); a second toggle plate (16) is fixedly connected to the bottom outer surface of the top column (14); a top plate (15) is fixedly connected to the top of the top column (14); a top plate (18) is arranged on the top of the top plate (15); a top plug (19) is fixedly connected to the middle of the top plate (18); a threaded rod (20) is inserted into the middle of the top plug (19).

2. The industrialized stainless steel jacket chromatography column according to claim 1, wherein: The cross-sectional shape of the support leg (2) is set to be a "Z" shape, the top of the support leg (2) is fixedly connected with a screw rod (23), the screw rod (23) passes through the wall of the base plate (1) and is sleeved with a hexagonal nut, and the bottom end of the support leg (2) is provided with a mounting hole.

3. The industrialized stainless steel jacket chromatographic column according to claim 1, wherein: The top end of the sealing plug (3) extends to the interior of the bottom column (6) and is adapted to the inner cavity of the bottom column (6); the positioning socket (8) corresponds to the positioning block (4); and the positioning block (4) passes through the middle of the positioning socket (8).

4. The industrialized stainless steel jacket chromatography column according to claim 1, characterized in that: The bottom column (6) and the top column (14) are both arranged between the three stabilizing rods (5); a connecting groove (17) is provided in the bottom inner cavity of the top column (14); the connecting groove (17) is matched with a connecting ring (10); and the connecting ring (10) is arranged in the middle of the connecting groove (17).

5. The industrialized stainless steel jacket chromatography column according to claim 1, characterized in that: The second limiting ring (12) is arranged at the bottom of the first limiting ring (9), the outer surface diameter of the bottom end of the top column (14) is adapted to the inner cavity diameter of the threaded sleeve (11), and the top end of the threaded sleeve (11) is sleeved on the bottom end of the top column (14) and is threadedly connected to the outer surface of the bottom end of the top column (14).

6. The industrialized stainless steel jacket chromatography column according to claim 1, characterized in that: The number of the second toggle plate (16) and the first toggle plate (13) is set to be multiple, the stabilizing rod (5) passes through the middle of the top plate (18) and is sleeved with a nut (22), the top plug (19) is adapted to the top inner cavity of the top column (14), and the bottom end of the top plug (19) extends to the inside of the top column (14).

7. The industrialized stainless steel jacket chromatography column according to claim 1, wherein: The threaded rod (20) is threadedly connected to the top plug (19); the top of the threaded rod (20) is fixedly connected to a turntable (21); a through pipe is provided in the middle of the turntable (21); the bottom of the threaded rod (20) is rotatably connected to a pressure plate; a sealing gasket is provided on the outer surface of the pressure plate.

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