Bile duct wall cell collection device

Abstract

The utility model relates to the technical field of medical instruments, in particular to a bile duct wall cell collecting device. The bile duct wall cell collection device comprises a catheter, a main guide wire, an auxiliary guide wire and a cytobrush assembly. A first channel for the main guide wire to penetrate through and a second channel for the auxiliary guide wire to penetrate through are arranged in the catheter. And the auxiliary guide wire is parallel to the main guide wire. The cytobrush assembly is arranged in the axial direction of the main guide wire. The cytobrush assembly comprises a skeleton, a connecting frame, a base and a flexible guide rod. And the plurality of frameworks are circularly arranged along the axis of the main guide wire. One end of the skeleton is connected with the main wire. Bristles for collecting are distributed on the framework. The base sleeves the main guide wire and has the degree of freedom of sliding in the axial direction of the main guide wire. The base is connected with the framework through a connecting frame. One end of the flexible guide rod is connected with the base, and the other end of the flexible guide rod is connected with the auxiliary guide wire. The bile duct wall cell collection device can conveniently penetrate through the narrow part of the bile duct, the collection difficulty is reduced, and the sampling success rate is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, and particularly relates to a bile duct wall cell collection device. Background Art

[0002] Endoscopic retrograde cholangiopancreatography (ERCP) is a medical procedure for diagnosing and treating bile duct and pancreatic duct diseases. Currently, almost all biliary tract pathologies in ERCP are obtained through cell brush sampling detection. During the actual sampling process, the cell brush is brushed up and down at the suspected lesion site of the bile duct through a guide wire, and then the collected bile duct wall cells are sent for pathological analysis.

[0003] For example, a cell brush for the biliary tract disclosed in Chinese patent document CN106923868A has an inner sleeve slidably arranged in an outer sleeve. The head end of the inner sleeve is provided with bristles for brushing tumor tissues at the stenosis, and the inner sleeve is also provided with a positioning member for facilitating the positioning of the bristles under X-ray. The cavity of the inner sleeve can penetrate the guide wire to assist the bristle part of the inner sleeve to pass through the narrow tissue. By pulling the bristles back and forth, the bristles brush the cells on the tissue. After the brushing is completed, the bristles are retracted into the outer sleeve and taken out of the human body for sampling.

[0004] However, during the actual sampling process of the above-mentioned cell brush for the biliary tract, due to the long path of the cell brush entering and exiting the bile duct and the difficulty of the cell brush passing through the stenosis of the bile duct, under the ERCP approach, the coaxially arranged guide wire lacks controllability over the cell brush, resulting in the sampling result being difficult to meet the expectation and affecting the detection accuracy. Summary of the Invention

[0005] The purpose of the utility model is to provide a collection device during the process of collecting bile duct wall cells, which is convenient for passing through the stenosis of the bile duct, reduces the collection difficulty, and improves the sampling success rate.

[0006] To achieve the above purpose, the utility model adopts the following scheme:

[0007] A bile duct wall cell collection device includes a catheter, a main guide wire, an auxiliary guide wire, and a cell brush assembly;

[0008] A first channel for passing the main guide wire and a second channel for passing the auxiliary guide wire are arranged in the catheter, and the auxiliary guide wire is arranged parallel to the main guide wire;

[0009] The cytobrush assembly is arranged along the axial direction of the main guide wire. The cytobrush assembly includes a framework, a connecting frame, a base and a flexible guide rod. A plurality of frameworks are arranged in a circular pattern along the axis of the main guide wire. One end of the framework is connected to the main guide wire. The framework is provided with bristles for collection. The base is sleeved on the main guide wire and has the freedom to slide along the axial direction of the main guide wire. The base is connected to the framework through the connecting frame. One end of the flexible guide rod is connected to the base, and the other end of the flexible guide rod is connected to the auxiliary guide wire.

[0010] Preferably, the cytobrush assembly has a contracted state and an expanded state. When the cytobrush assembly is in the contracted state, the base slides towards the head end direction of the main guide wire to the first limit position, and the free end of the framework contracts towards the main guide wire. When the cytobrush assembly is in the expanded state, the base slides towards the tail end direction of the main guide wire to the second limit position, and the framework is fully unfolded to form a fan-shaped sampling structure.

[0011] Preferably, a first marker post and a second marker post are arranged on the main guide wire. An acquisition area is formed between the first marker post and the second marker post. The cytobrush assembly is located within the acquisition area. With this arrangement, the first marker post and the second marker post are used to clearly mark the working range of the cytobrush assembly, helping the operator to accurately locate the acquisition area during the operation, improving the sampling accuracy. By defining the acquisition area with the marker posts, the interference and damage risks to non-target areas are reduced. The cytobrush assembly only unfolds and works within the acquisition area, avoiding unnecessary brushing and friction in non-target areas and reducing the occurrence of potential complications.

[0012] Preferably, a plurality of cytobrush assemblies are arranged in a linear array along the axial direction of the main guide wire within the acquisition area. With this arrangement, the plurality of cytobrush assemblies are arranged in a linear array, enabling cell collection to be carried out simultaneously at multiple positions during each operation. This multi-point sampling method greatly improves the collection efficiency, shortens the operation time, and reduces the number of repeated operations.

[0013] Preferably, the first channel and the second channel are separated by a partition, and the partition is connected to the inner wall of the catheter. With this arrangement, the partition is connected to the inner wall of the catheter, increasing the stability and rigidity of the overall structure of the catheter, making the catheter more robust during the operation, reducing the risk of bending and deformation, and ensuring the stability and accuracy of the operation.

[0014] Compared with the prior art, the bile duct wall cell collection device provided by the present utility model has the following substantial features and improvements: The bile duct wall cell collection device adopts a dual-channel design of a main guide wire and an auxiliary guide wire, enabling the cell brush assembly to be more stable and accurate in positioning within the bile duct. The main guide wire provides a reliable guiding direction, while the auxiliary guide wire enhances the stability of the device, reducing the risk of accidental injury to the bile duct wall during the collection process. Moreover, the cell brush assembly has high flexibility. The base can freely slide along the axial direction of the main guide wire. With the design of the flexible guide rod, the device can flexibly adapt to bile ducts of different shapes and sizes, greatly improving the applicability. Through the circular arrangement of multiple skeletons and the sliding design of the base, the operator can more easily control the movement of the cell brush assembly, simplifying the operation steps of the collection process and improving the convenience and safety of the operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 FIG. is a schematic structural diagram of a bile duct wall cell collection device in an embodiment of the present utility model.

[0016] Figure 2 FIG. is a simplified schematic structural diagram of a cell brush assembly in an embodiment of the present utility model.

[0017] Figure 3 FIG. is a simplified schematic structural diagram of another cell brush assembly in an embodiment of the present utility model.

[0018] Reference numerals: 1, catheter; 2, main guide wire; 3, auxiliary guide wire; 4, cell brush assembly; 5, first marker post; 6, second marker post; 7, first channel; 8, second channel; 9, partition; 10, brush hair rod; 11, fan-shaped structure; 41, skeleton; 42, connecting frame; 43, base; 44, flexible guide rod. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0019] The following will describe in detail the specific embodiments of the present utility model with reference to the accompanying drawings.

[0020] As Figure 1 shown, an embodiment of the present utility model provides a bile duct wall cell collection device, aiming to facilitate passing through the narrow part of the bile duct, reducing the collection difficulty and improving the sampling success rate.

[0021] In the embodiment of the present utility model, a bile duct wall cell collection device adopts a dual-channel design of a main guide wire 2 and an auxiliary guide wire 3, enabling the cytobrush assembly 4 to be more stable and accurate in positioning within the bile duct. The main guide wire 2 provides a reliable guidance, while the auxiliary guide wire 3 enhances the stability of the device, reducing the risk of accidental injury to the bile duct wall during the collection process. Moreover, the cytobrush assembly 4 has high flexibility. The base 43 can freely slide along the axial direction of the main guide wire 2. Combined with the design of the flexible guide rod 44, the device can flexibly adapt to bile ducts with different shapes and sizes, greatly improving the applicability, reducing the collection difficulty, and increasing the sampling success rate.

[0022] As Figure 1 shown, a bile duct wall cell collection device includes a catheter 1, a main guide wire 2, an auxiliary guide wire 3, and a cytobrush assembly 4. A first channel 7 for threading the main guide wire 2 and a second channel 8 for threading the auxiliary guide wire 3 are provided inside the catheter 1. The auxiliary guide wire 3 is arranged parallel to the main guide wire 2.

[0023] As Figure 1 shown, the cytobrush assembly 4 is arranged along the axial direction of the main guide wire 2. The cytobrush assembly 4 includes a skeleton 41, a connecting frame 42, a base 43, and a flexible guide rod 44. Multiple skeletons 41 are arranged in a circular pattern along the axis of the main guide wire 2. One end of the skeleton 41 is connected to the main guide wire 2. Brush hairs for collection are arranged on the skeleton 41. The base 43 is sleeved on the main guide wire 2 and has the freedom to slide along the axial direction of the main guide wire 2. The base 43 is connected to the skeleton 41 through the connecting frame 42. One end of the flexible guide rod 44 is connected to the base 43, and the other end of the flexible guide rod 44 is connected to the auxiliary guide wire 3. For example, each cytobrush assembly 4 is provided with 3 - 6 skeletons 41.

[0024] Among them, the cytobrush assembly 4 has a contracted state and an expanded state. During the process of inserting and withdrawing the device from the bile duct, the cytobrush assembly 4 can remain in the contracted state to avoid unnecessary friction and damage caused by the brush hairs in the narrow bile duct. It is only opened for sampling when reaching the target sampling area, thus effectively reducing physical damage and irritation to the bile duct wall.

[0025] When the cytobrush assembly 4 is in the contracted state, driven by the auxiliary guide wire 3, the base 43 slides towards the head end direction of the main guide wire 2 to the first limit position, and the free end of the skeleton 41 contracts towards the main guide wire 2. When the cytobrush assembly 4 is in the contracted state, the overall volume of the cytobrush assembly 4 is more compact, reducing the resistance and friction during insertion and passing through the bile duct. This enables the device to reach the target area more smoothly, improving the convenience and efficiency of the operation.

[0026] When the cell brush assembly 4 is in the open state, driven by the auxiliary guide wire 3, the base 43 slides towards the end of the main guide wire 2 to the second limit position, and the framework 41 is fully unfolded to form a fan-shaped sampling structure. In this way, it is ensured that the bristles can contact the bile duct wall with the largest area, so as to perform comprehensive and efficient cell collection. The operator can accurately control the opening and contraction of the cell brush assembly 4 according to needs, ensuring the flexibility and accuracy of the sampling process.

[0027] The operator can dynamically adjust the contraction and opening states of the cell brush assembly 4 according to real-time needs. For example, when passing through a narrow bile duct segment, it can be kept in the contracted state to pass smoothly; in a spacious bile duct segment or the target sampling area, it can be opened to maximize the sampling effect. Such a design greatly enhances the flexibility and adaptability of the operation.

[0028] As Figure 1 shown, a first marker post 5 and a second marker post 6 are provided on the main guide wire 2. An acquisition area is formed between the first marker post 5 and the second marker post 6. The cell brush assembly 4 is located within the acquisition area. With such a setting, the first marker post 5 and the second marker post 6 are used to clearly mark the working range of the cell brush assembly 4, helping the operator to accurately locate the acquisition area during the operation, improving the sampling accuracy. By defining the acquisition area with the marker posts, the interference and damage risks to non-target areas are reduced. The cell brush assembly 4 only unfolds and works within the acquisition area, avoiding unnecessary brushing and friction in non-target areas and reducing the occurrence of potential complications.

[0029] In order to further improve the sampling efficiency, as Figure 1 shown, multiple cell brush assemblies 4 are arranged in a linear array along the axial direction of the main guide wire 2 within the acquisition area. With such a setting, the multiple cell brush assemblies 4 are arranged in a linear array, enabling cell collection to be carried out simultaneously at multiple positions during each operation. This multi-point sampling method greatly improves the sampling efficiency, shortens the operation time, and reduces the number of repeated operations. The number of cell brush assemblies 4 can be selected according to the size of the acquisition area. For example, the number of cell brush assemblies 4 is preferably 3 - 5.

[0030] As Figure 1 shown, the first channel 7 and the second channel 8 are separated by a partition 9. The partition 9 is connected to the inner wall of the catheter 1. With such a setting, the partition 9 is connected to the inner wall of the catheter 1, increasing the stability and rigidity of the overall structure of the catheter 1, making the catheter 1 more robust during the operation, reducing the risk of bending and deformation, and ensuring the stability and accuracy of the operation.

[0031] When the bile duct wall cell collection device proposed in the embodiment of the present utility model is used, its structure can be appropriately simplified according to actual sampling requirements. For example, as Figure 2As shown in the figure, the cell brush assembly 4 is simplified to a bristle rod 10. The bristle rod 10 has unidirectional shrinkability. When passing through the bile duct stenosis, the bristle rod 10 shrinks towards the guide wire 2, improving the passability; when the guide wire 2 drives the bristle rod 10 to move in the reverse direction, the bristle rod 10 gradually opens under the action of the bile duct wall, thereby collecting bile duct wall cells. Another example is, as Figure 3 shown, the cell brush assembly 4 is simplified to a fan-shaped structure 11. The fan-shaped structure 11 made of flexible material has shrinkability in the radial direction of the bile duct, and the bottom edge of the fan is convenient for collecting tumor tissues.

[0032] The utility model is not limited to the specific technical solutions described in the above embodiments. In addition to the above embodiments, the utility model can also have other embodiments. For those skilled in the art, any technical solutions formed by making any modifications, equivalent replacements, improvements, etc. within the spirit and principle of the utility model shall be included within the protection scope of the utility model.

Claims

1. A bile duct wall cell collection device, characterized in that, It includes a catheter (1), a main guide wire (2), an auxiliary guide wire (3) and a cytobrush assembly (4); A first channel (7) for threading the main guide wire (2) and a second channel (8) for threading the auxiliary guide wire (3) are provided inside the catheter (1), and the auxiliary guide wire (3) is arranged parallel to the main guide wire (2); The cytobrush assembly (4) is arranged along the axial direction of the main guide wire (2). The cytobrush assembly (4) includes a framework (41), a connecting frame (42), a base (43) and a flexible guide rod (44). A plurality of frameworks (41) are arranged in a circular pattern along the axis of the main guide wire (2). One end of the framework (41) is connected to the main guide wire (2). Brush hairs for collection are arranged on the framework (41). The base (43) is sleeved on the main guide wire (2) and has the freedom to slide axially along the main guide wire (2). The base (43) is connected to the framework (41) through the connecting frame (42). One end of the flexible guide rod (44) is connected to the base (43), and the other end of the flexible guide rod (44) is connected to the auxiliary guide wire (3).

2. The bile duct wall cell collection device according to claim 1, wherein The cytobrush assembly (4) has a contracted state and an expanded state; When the cytobrush assembly (4) is in the contracted state, the base (43) slides towards the head end direction of the main guide wire (2) to a first limit position, and the free end of the framework (41) contracts towards the main guide wire (2); When the cytobrush assembly (4) is in the expanded state, the base (43) slides towards the tail end direction of the main guide wire (2) to a second limit position, and the framework (41) fully unfolds to form a fan-shaped sampling structure.

3. The bile duct wall cell collection device according to claim 1, characterized in that, A first marker post (5) and a second marker post (6) are provided on the main guide wire (2). A collection area is formed between the first marker post (5) and the second marker post (6), and the cytobrush assembly (4) is located within the collection area.

4. The bile duct wall cell collection device according to claim 3, characterized in that, A plurality of cytobrush assemblies (4) are arranged in a linear array along the axial direction of the main guide wire (2) within the collection area.

5. The bile duct wall cell collection device according to claim 1, characterized in that The first channel (7) and the second channel (8) are separated by a partition (9), and the partition (9) is connected to the inner wall of the catheter (1).

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