High-flux PCR reaction reagent freeze-drying plate

By setting up test tube slots and material storage components on the freeze-drying rack, the time-consuming and labor-intensive and leaking problems of reagent tubes are solved, and efficient batch pickup and high-throughput freeze-drying are achieved.

CN223153896UActive Publication Date: 2025-07-25SUZHOU KANGJI DIAGNOSTIC REAGENT CO LTD
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Patent Information

Application Number
CN202422423266.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-09
Publication Date
2025-07-25
Estimated Expiration
2034-10-09

AI Technical Summary

Technical Problem

The reagent tubes on existing freeze-drying racks are time-consuming and labor-intensive when taken, and when taken independently, they can easily lead to the openings of multiple reagent tubes leaking out, affecting the freeze-drying effect.

Method used

The test tube slot and material storage assembly are installed on the freeze-drying rack, including the test tube body, limit outer ring and installation assembly. The batch fixation and independent removal of the reagent tubes are achieved through the limit groove and moving groove, and the splicing of the freeze-drying rack is achieved by combining the connecting slot and the insertion legs to improve the operating efficiency.

Benefits of technology

It realizes efficient batch pickup of reagent tubes, avoids leakage of the top opening, improves the freeze-drying effect, and supports high-throughput freeze-drying operation.

✦ Generated by Eureka AI based on patent content.

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    Figure CN223153896U_ABST
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Abstract

The utility model discloses a high-flux PCR reaction reagent freeze-drying plate, and relates to the technical field of PCR reaction reagent freeze-drying plates, the high-flux PCR reaction reagent freeze-drying plate comprises a freeze-drying rack body, the surface of the freeze-drying rack body is provided with a test tube slot, the inside of the test tube slot is provided with a material storage assembly, and the material storage assembly is provided with a material storage groove. A mounting assembly is arranged at the upper end of the material storage assembly, the material storage assembly comprises a test tube body, a limiting outer ring is hot-melted on the outer wall of the test tube body, a top end outer ring is integrated at the top end of the test tube body, the material storage assembly comprises an upper top plate and a center plate, and a lower bottom plate is arranged at the lower end of the center plate; according to the scheme, the problems that when reagent tubes on an existing freeze-drying frame need to be taken one by one, time and labor are wasted, and when the reagent tubes are taken independently, a cover plate of the freeze-drying frame needs to be pulled, so that openings in the top ends of the reagent tubes leak out, and the freeze-drying effect is affected are solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of PCR reaction reagent freeze-drying plates, and particularly relates to a high-throughput PCR reaction reagent freeze-drying plate. Background Technique

[0002] ‌PCR reaction reagent freeze-drying‌ is a method for treating PCR reaction reagents through freeze-drying technology. This method involves pre-cooling and freezing the PCR reaction reagents into solids, and then under vacuum conditions, through sublimation, more than 95% of the water is evaporated. At the same time, the protective agent acts as a solidifying agent and will not collapse during sublimation, ensuring the morphology of the freeze-dried products. When performing freeze-drying, the PCR reaction reagents are stored in reagent tubes, and the reagent tubes are placed on the freeze-drying rack;

[0003] For example, the Chinese authorized patent (reagent rack) with the publication number CN205797263U: includes a cabinet body, a column, and a panel. The column is detachably installed on the cabinet body. Threaded holes are opened on the column, and through holes corresponding to the threaded holes are respectively opened on both sides of the panel. Baffles are provided on the periphery of the panel, and both sides of the panel are respectively threadedly connected to adjacent columns through screws. The beneficial effect of the utility model is that it can stably place reagent bottles and protect the cleanliness of the reagent bottles.

[0004] However, when taking the reagent tubes on the existing freeze-drying rack, they need to be taken one by one, which is time-consuming and laborious. And when taking them independently, the cover plate of the freeze-drying rack needs to be pulled, which will cause the top openings of multiple reagent tubes to leak out, thus affecting the freeze-drying effect; Therefore, it does not meet the existing requirements, and for this reason, we propose a high-throughput PCR reaction reagent freeze-drying plate. Content of the Utility Model

[0005] The purpose of the utility model is to provide a high-throughput PCR reaction reagent freeze-drying plate to solve the problems in the above-mentioned background technique that when taking the reagent tubes on the existing freeze-drying rack, they need to be taken one by one, which is time-consuming and laborious, and when taking them independently, the cover plate of the freeze-drying rack needs to be pulled, which will cause the top openings of multiple reagent tubes to leak out, thus affecting the freeze-drying effect.

[0006] To achieve the above purpose, the utility model provides the following technical solution: A high-throughput PCR reaction reagent freeze-drying plate, including: a freeze-drying rack body, a test tube slot is arranged on the surface of the freeze-drying rack body, a storage component is arranged inside the test tube slot, an installation component is arranged at the upper end of the storage component, the storage component includes a test tube body, a limiting outer ring is hot-melted on the outer wall of the test tube body, and a top outer ring is integrated at the top of the test tube body.

[0007] Preferably, the stock storage component includes an upper top plate and a central plate, and a lower bottom plate is arranged at the lower end of the central plate.

[0008] Preferably, a limiting groove is arranged on the surface of the central plate, and a moving groove is arranged on the surface of the lower bottom plate. A plurality of limiting grooves and moving grooves are provided, and the limiting grooves and the moving grooves correspond to each other one by one.

[0009] Preferably, a screw safety groove is arranged on the upper surface of the corner of the upper top plate, and a fixing screw is arranged inside the screw safety groove. One end of the fixing screw passes through the upper top plate and the central plate and is threadedly fixed to the lower bottom plate.

[0010] Preferably, connection slots are arranged on the upper surfaces of the corners of the freeze-drying rack body, and connection legs are arranged on the lower surfaces of the corners of the freeze-drying rack body. The connection legs are fixedly heat-melted to the freeze-drying rack body.

[0011] Preferably, handles are arranged on both side surfaces of the freeze-drying rack body, and the handles are fixedly heat-melted to the freeze-drying rack body.

[0012] Preferably, the outer circle of the top end is inserted into the limiting groove, and the tube body of the test tube moves along the moving groove.

[0013] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0014] By arranging an installation component above the freeze-drying rack body of the present utility model, the tube body of the test tube containing the PCR reaction reagent is inserted into the test tube slot. After a row is arranged, the installation component is fixedly installed from one side of the outer circle of the top end. When it is necessary to take out the stock storage component, the installation component is directly lifted upward, and then a row of stock storage components can be taken out. Then, according to the needs, the stock storage component at the corresponding position is selected, and the stock storage component is moved along the opening of the limiting groove, so that the stock storage component can be separated from the installation component. In this way, the independent taking of the stock storage component is realized, and the phenomenon that the top openings of other stock storage components leak out will not occur, improving the freeze-drying effect and solving the problems that when the reagent tubes on the existing freeze-drying rack are taken, they need to be taken one by one, which is time-consuming and laborious, and when taking them independently, the cover plate of the freeze-drying rack needs to be pulled, which will cause the top openings of multiple reagent tubes to leak out, thus affecting the freeze-drying effect.

[0015] By respectively arranging connection slots and connection legs on the upper and lower surfaces of the corners of the freeze-drying rack body, when two freeze-drying rack bodies are freeze-dried together, the connection legs of one freeze-drying rack body are inserted into the connection slots of the other freeze-drying rack body to realize the splicing of multiple freeze-drying rack bodies for high-throughput freeze-drying operation. Description of the Drawings

[0016] Figure 1It is a schematic diagram of the overall structure of the utility model;

[0017] Figure 2 This is a bottom view of the structure of the installation assembly of the utility model;

[0018] Figure 3 This is a schematic diagram of the top view of the installation assembly of the utility model;

[0019] Figure 4 This is a schematic diagram of the structure of the material storage component of the utility model;

[0020] In the figure: 1. Freeze-drying rack body; 2. Test tube slot; 3. Connection slot; 4. Connection leg; 5. Material storage assembly; 6. Installation assembly; 7. Upper top plate; 8. Center plate; 9. Lower bottom plate; 10. Limiting slot; 11. Moving slot; 12. Fixing screw; 13. Test tube body; 14. Limiting outer ring; 15. Top outer ring; 16. Screw safety slot; 17. Handle. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0022] See also Figures 1-4 The utility model provides an embodiment: a high-throughput PCR reaction reagent freeze-drying plate, comprising: a freeze-drying rack body 1, a test tube slot 2 is arranged on the surface of the freeze-drying rack body 1, a material storage component 5 is arranged inside the test tube slot 2, and a mounting component 6 is arranged on the upper end of the material storage component 5, the material storage component 5 comprises a test tube body 13, the outer wall of the test tube body 13 is hot-melted with a limiting outer ring 14, and the top of the test tube body 13 is integrated with a top outer ring 15, the material storage component 5 comprises an upper top plate 7 and a center plate 8, a lower bottom plate 9 is arranged at the lower end of the center plate 8, a limiting groove 10 is arranged on the surface of the center plate 8, and a moving groove 11 is arranged on the surface of the lower bottom plate 9, and a plurality of limiting grooves 10 and moving grooves 11 are arranged, and the limiting grooves 10 and the moving grooves 11 correspond to each other one by one, the top outer ring 15 is inserted into the limiting groove 10, and the test tube body 13 moves along the moving groove 11.

[0023] Insert the tube body 13 containing the PCR reaction reagent into the test tube slot 2. After arranging a row, fix the installation component 6 from one side of the top outer ring 15. Insert the top outer ring 15 into the limit slot 10 to limit and fix the top outer ring 15, thus connecting the material storage component 5 and the installation component 6. When it is necessary to remove the material storage component 5, directly lift the installation component 6 upward, and then a row of material storage components 5 can be taken out. Then, according to the needs, select the material storage component 5 at the corresponding position and move the material storage component 5 along the opening of the limit slot 10 to separate the material storage component 5 from the installation component 6. In this way, the independent taking of the material storage component 5 is realized, and the phenomenon of leakage from the top opening of other material storage components 5 will not occur, improving the freeze-drying effect.

[0024] Please refer to Figure 2 、 3 On the upper surface of the corner of the upper top plate 7, there is a screw safety groove 16. Inside the screw safety groove 16, there is a fixing screw 12, and one end of the fixing screw 12 passes through the upper top plate 7 and the center plate 8 and is threadedly fixed to the lower bottom plate 9, realizing the separable disassembly of the upper top plate 7, the center plate 8, and the lower bottom plate 9. Frequently fixing the top outer ring 15 through the friction effect is likely to cause wear and needs to be replaced. By replacing it in a separable disassembly manner, it is convenient to reduce the replacement cost.

[0025] Please refer to Figure 1 On the upper surface of each corner of the freeze-drying rack body 1, there is a connection slot 3, and on the lower surface of each corner of the freeze-drying rack body 1, there is a connection leg 4, and the connection leg 4 is heat-melt fixed to the freeze-drying rack body 1. When two freeze-drying rack bodies 1 are freeze-dried together, insert the connection leg 4 of one freeze-drying rack body 1 into the connection slot 3 of the other freeze-drying rack body 1 to realize the splicing of multiple freeze-drying rack bodies 1 for high-throughput freeze-drying operations.

[0026] Please refer to Figure 1 On both side surfaces of the freeze-drying rack body 1, there are handles 17, and the handles 17 are heat-melt fixed to the freeze-drying rack body 1, which is convenient for lifting the freeze-drying rack body 1.

[0027] Working principle: When in use, insert the test tube body 13 filled with PCR reaction reagents into the test tube slot 2. Rely on the release of the limit outer ring 14 from the freeze-drying rack body 1 to limit the test tube body 13 to prevent it from falling. After a row is arranged, fix the installation component 6 from one side of the top outer ring 15. The top outer ring 15 is inserted into the limit slot 10, and the test tube body 13 moves along the moving slot 11. Due to the dimensional difference between the limit slot 10 and the moving slot 11, the top outer ring 15 is limited and fixed, realizing the connection between the material storage component 5 and the installation component 6, and the fixation is achieved through friction. When it is necessary to remove the material storage component 5, directly lift the installation component 6 upward, and then a row of material storage components 5 can be removed. Then, according to the needs, select the material storage component 5 at the corresponding position and move the material storage component 5 along the opening of the limit slot 10, and the separation of the material storage component 5 and the installation component 6 can be realized. In this way, the independent taking of the material storage component 5 is achieved, and the phenomenon of leakage from the top opening of other material storage components 5 will not occur, improving the freeze-drying effect. When two freeze-drying rack bodies 1 are used for freeze-drying together, insert the connecting leg 4 of one freeze-drying rack body 1 into the connecting slot 3 of the other freeze-drying rack body 1 to realize the splicing of multiple freeze-drying rack bodies 1 for high-throughput freeze-drying operation.

[0028] For those skilled in the art, it is obvious that the present utility model is not limited to the details of the above exemplary embodiments, and can be implemented in other specific forms without departing from the spirit or basic characteristics of the present utility model. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting. The scope of the present utility model is defined by the appended claims rather than the above description. Therefore, all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the present utility model. Any reference signs in the claims should not be regarded as limiting the claims involved.

Claims

1. A high-throughput PCR reaction reagent freeze-dried plate, comprising a freeze-drying rack body (1), characterized in that: The surface of the freeze-drying rack body (1) is provided with test tube slots (2). A material storage component (5) is arranged inside the test tube slots (2). An installation component (6) is arranged at the upper end of the material storage component (5). The material storage component (5) includes a test tube body (13). A limiting outer ring (14) is heat-melted on the outer wall of the test tube body (13). The top end of the test tube body (13) is integrally formed with a top outer ring (15).

2. The lyophilized plate of a high-throughput PCR reaction reagent according to claim 1, wherein: The material storage component (5) includes an upper top plate (7) and a central plate (8). A lower bottom plate (9) is arranged at the lower end of the central plate (8).

3. The high-throughput PCR reaction reagent lyophilized plate according to claim 2, wherein: Limiting grooves (10) are arranged on the surface of the central plate (8). Moving grooves (11) are arranged on the surface of the lower bottom plate (9). A plurality of limiting grooves (10) and moving grooves (11) are provided, and the limiting grooves (10) and the moving grooves (11) correspond to each other one by one.

4. A high-throughput PCR reaction reagent lyophilized plate according to claim 3, characterized in that: Screw safety grooves (16) are arranged on the upper surface of the corners of the upper top plate (7). Fixing screws (12) are arranged inside the screw safety grooves (16). One end of the fixing screw (12) passes through the upper top plate (7) and the central plate (8) and is threadedly fixed to the lower bottom plate (9).

5. A high-throughput PCR reaction reagent lyophilized plate according to claim 1, characterized in that: Connection slots (3) are arranged on the upper surfaces of the corners of the freeze-drying rack body (1). Connection legs (4) are arranged on the lower surfaces of the corners of the freeze-drying rack body (1). The connection legs (4) are heat-melted and fixed to the freeze-drying rack body (1).

6. A high-throughput PCR reaction reagent lyophilized plate according to claim 1, characterized in that: Handles (17) are arranged on both side surfaces of the freeze-drying rack body (1). The handles (17) are heat-melted and fixed to the freeze-drying rack body (1).

7. A high-throughput PCR reaction reagent lyophilized plate according to claim 3, characterized in that: The top outer ring (15) is inserted into the limiting groove (10) internally, and the test tube body (13) moves along the moving groove (11).

Citation Information

Patent Citations

  • Reagent rack

    CN205797263U