Fluorescence detection structure

By designing a fluorescence detection structure compatible with cuvettes and centrifuge tubes, the problem of incompatibility of existing instruments is solved, and the fluorescence detection compatibility between cuvettes and centrifuge tubes is achieved, which improves the applicability and operational convenience.

CN223154854UActive Publication Date: 2025-07-25CHONGQING KAIAO BIOLOGICAL TECH CO TLD
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Patent Information

Application Number
CN202421467894.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-25
Publication Date
2025-07-25
Estimated Expiration
2034-06-25

AI Technical Summary

Technical Problem

Existing fluorescence detection instruments are not compatible with centrifuge tubes and cuvettes, and their applicability is not high.

Method used

A fluorescence detection structure is designed, including a frame, a detection rack and a mount, which can install cuvettes and centrifuge tubes at the same time, and dock the light source channel through the light hole and channel design, which is suitable for fluorescence detection of cuvettes and centrifuge tubes.

Benefits of technology

It realizes compatible use of cuvettes and centrifuge tubes, improves the applicability of fluorescence detection, and facilitates maintenance and detection operations.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a fluorescence detection structure, which is mounted on a detector and used for mounting a centrifuge tube, and comprises a detection frame, the detector is provided with a containing cavity, the detection frame is mounted in the containing cavity, the detection frame is provided with a clamping groove, and the detection frame is provided with two first through holes which correspond to light through holes of the detector and penetrate through the clamping groove; the mounting base is arranged in the clamping groove in a penetrating mode and provided with a mounting groove used for mounting the centrifugal tube, the mounting base is provided with second through holes corresponding to the two first through holes respectively, and when the mounting base and the detection frame are both located in the containing cavity, the light through hole, the first through holes and the second through holes form a light source channel. When a centrifugal tube needs to be used for detection, the centrifugal tube is directly arranged in the mounting groove in a penetrating mode under the cooperation of the mounting base, fluorescence detection can be conducted on the centrifugal tube by directly clamping the mounting base into the clamping groove after the centrifugal tube and the mounting base are assembled, the centrifugal tube and the mounting base are used in a compatible mode, and applicability is high.
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Description

Technical Field

[0001] The utility model relates to the technical field of biological laboratory instruments, in particular to a fluorescence detection structure. Background Art

[0002] At present, fluorescence is generally detected by a fluorescence spectrophotometer or a fluorometer. The fluorescence spectrophotometer uses a cuvette for detection. During the detection, the sample needs to be added to the cuvette. The light emitted by a high-pressure mercury lamp or a xenon lamp is irradiated onto the sample cell in the cuvette through a filter, exciting the fluorescent substances in the sample to emit fluorescence. After the fluorescence is filtered and reflected, it is received by the detector. While the fluorometer needs to use a centrifuge tube for detection. The excitation light is irradiated onto the sample cell in the centrifuge tube, and the fluorescence emitted by the measured fluorescent substances under the irradiation of the excitation light becomes monochromatic fluorescence after passing through a monochromator and then irradiates onto the photomultiplier tube for sample measurement. The photocurrent generated by it is amplified by an amplifier and output to a recorder. However, at present, both of the two instruments for measuring fluorescence have requirements for the sample containers, and it is impossible to use both a cuvette and a centrifuge tube, resulting in low applicability. Content of the Utility Model

[0003] Aiming at the deficiencies in the prior art, the utility model provides a fluorescence detection structure, which solves the problem that the detection instruments in the prior art cannot be compatible with centrifuge tubes and cuvettes.

[0004] According to the embodiments of the utility model, the following technical solutions are adopted:

[0005] A fluorescence detection structure for installing a centrifuge tube, comprising:

[0006] A frame body having a receiving cavity and provided with light passing holes with mutually perpendicular axes;

[0007] A detection frame installed in the receiving cavity, provided with a card slot, and further provided with two first through holes corresponding to the light passing holes and penetrating through to the card slot;

[0008] A mounting seat passing through the card slot and having a mounting groove for mounting a centrifuge tube. The mounting seat is provided with second through holes respectively corresponding to the two first through holes. When both the mounting seat and the detection frame are located in the receiving cavity, the light passing holes, the first through holes and the second through holes form a light source channel.

[0009] Preferably, a positioning pin is provided at the top of the mounting seat, and a positioning groove is provided in the card slot. When the mounting seat is clamped in the card slot, the positioning pin passes through the positioning groove.

[0010] Preferably, the edge of the mouth of the receiving cavity has a guiding inclined surface.

[0011] Preferably, the height of the mounting seat is α, and the depth of the card slot is β, and α and β satisfy α > β.

[0012] Preferably, the top of the mounting base is recessed inward to form a groove.

[0013] Preferably, there are four second through holes, and the four second through holes are arranged in an array on the circumferential side of the mounting base.

[0014] Preferably, it further includes two protective blocks, and the two protective blocks are respectively rotatably arranged at the mouth of the clamping groove through rotating shafts, and torsion springs are arranged on the rotating shafts.

[0015] Preferably, a storage groove corresponding to the protective block is formed inside the clamping groove.

[0016] Compared with the prior art, the utility model has the following beneficial effects:

[0017] In this solution, the accommodation cavity in the frame body facilitates the installation of the detection rack for subsequent maintenance use. And the clamping groove in the detection rack is a groove structure. When a colorimetric cuvette needs to be used for detection, the colorimetric cuvette can be directly inserted into the clamping groove, so that the clamping groove can be directly used as a sample cell to perform fluorescence detection on the colorimetric cuvette. When a centrifuge tube needs to be used for detection, with the cooperation of the mounting base, the centrifuge tube can be directly inserted into the mounting groove, and after the two are assembled, the mounting base can be directly clamped into the clamping groove to perform fluorescence detection on the centrifuge tube. The two are compatible for use, and the applicability is relatively high. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic assembly structure diagram of an embodiment of the utility model.

[0019] Figure 2 It is an exploded structure diagram of an embodiment of the utility model.

[0020] Figure 3 It is a schematic cross-sectional structure diagram of the detection rack in an embodiment of the utility model.

[0021] Figure 4 For Figure 3 an enlarged structural diagram of area A in

[0022] In the above-mentioned drawings: 1, frame body; 2, detection rack; 3, centrifuge tube; 4, first through hole; 5, mounting base; 6, mounting groove; 7, groove; 8, second through hole; 9, guiding inclined surface; 10, accommodation cavity; 11, protective block; 12, clamping groove; 13, positioning groove; 14, positioning pin; 15, rotating shaft; 16, torsion spring; 17, storage groove; 18, light passing hole. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0023] The technical solutions in the utility model will be further described below with reference to the drawings and embodiments.

[0024] Such as Figures 1 to 3As shown in the figure, an embodiment of the present utility model provides a fluorescence detection structure for installing a centrifuge tube 3, including:

[0025] A frame body 1 having a receiving cavity 10 and provided with light passing holes 18 whose axes are perpendicular to each other;

[0026] A detection frame 2 is installed in the receiving cavity 10, provided with a card slot 12, and also provided with two first through holes 4 corresponding to the light passing holes 18 and penetrating through to the card slot 12;

[0027] A mounting seat 5 is inserted through the card slot 12 and has a mounting groove 6 for mounting the centrifuge tube 3. The mounting seat 5 is provided with second through holes 8 corresponding to the two first through holes 4 respectively. When both the mounting seat 5 and the detection frame 2 are located in the receiving cavity 10, the light passing holes 18, the first through holes 4 and the second through holes 8 form a light source channel.

[0028] In the embodiment of the present utility model, when detecting a cuvette, since the cuvette has a regular shape and is convenient to place, it can be directly placed in the card slot 12, so that the cuvette is limited by the card slot 12 and will not shift or move. In the normal state, the detection frame 2 is always installed in the receiving cavity 10 of the frame body 1, and the two first through holes 4 respectively correspond to the light passing holes 18 whose axes are perpendicular to each other, so that Figure 1 For example, the light emitted by the xenon lamp enters the card slot 12 through the right light passing hole 18 and irradiates the sample in the cuvette, and the light emitted by the sample is emitted through the left light passing hole 18 and reaches the detector to complete the detection.

[0029] When detecting the centrifuge tube 3, on the premise of installing the detection frame 2, the centrifuge tube 3 can be directly inserted into the mounting groove 6 of the mounting seat 5 first. The mounting groove 6 fits the shape of the centrifuge tube 3 to ensure stable installation. After the centrifuge tube 3 is installed, the mounting seat 5 is directly snapped into the card slot 12. After being snapped in place, the second through hole 8 of the mounting seat 5 directly corresponds to the first through hole 4, so that fluorescence detection of the centrifuge tube 3 can be quickly carried out. The centrifuge tube 3 and the cuvette are compatible for use, with high applicability. When performing fluorescence detection, either the cuvette can be used as a container or the centrifuge tube 3 can be used as a container, providing more choices.

[0030] Specifically, as Figure 3 shown, a positioning pin 14 is provided at the top of the mounting seat 5, and a positioning groove 13 is provided in the card slot 12. When the mounting seat 5 is snapped into the card slot 12, the positioning pin 14 is inserted through the positioning groove 13. In order to facilitate the installation of the mounting seat 5 into the card slot 12, the diameter of the card slot 12 is larger than the outer diameter of the mounting seat 5, so there is a small moving space after the mounting seat 5 is installed into the card slot 12. Therefore, with the cooperation of the positioning groove 13 and the positioning pin 14, the mounting seat 5 can be positioned and installed in the card slot 12, ensuring the alignment accuracy of the second through hole 8 and the first through hole 4 and ensuring the light passing property of the light source.

[0031] Specifically, as Figure 2 shown, the edge of the mouth of the accommodation cavity 10 has a guiding inclined surface 9. When the mounting base 5 is installed on the detection rack 2 inside the frame body 1, under the action of the guiding inclined surface 9, the mounting base 5 can be guided into the card slot 12, which is convenient for installation.

[0032] Specifically, as Figure 3 shown, the height of the mounting base 5 is α, and the depth of the card slot 12 is β. α and β satisfy α > β, so that the overall height of the mounting base 5 is higher than the depth of the card slot 12. After the mounting base 5 is installed in the card slot 12, the top of the mounting base 5 protrudes from the mouth of the card slot 12, which is convenient for separating the mounting base 5 from the card slot 12.

[0033] Specifically, as Figure 1 shown, the top of the mounting base 5 is recessed inward to form a groove 7, which is convenient for fingers to hold the top of the mounting base 5 and also plays a certain anti-slip role.

[0034] Specifically, as Figure 1 shown, there are four second through holes 8, and the four second through holes 8 are arranged in an array on the periphery of the mounting base 5. The axes of the four second through holes 8 are perpendicular to each other in sequence. When the mounting base 5 is installed in the card slot 12 in any direction, there are two second through holes 8 corresponding to two first through holes 4, so that it is convenient to install the mounting base 5 without considering the arrangement direction of the second through holes 8.

[0035] Based on the above solution, as Figure 3 shown in Figure 4 and

[0036] shown, it further includes two protective blocks 11. The two protective blocks 11 are respectively rotatably arranged at the mouth of the card slot 12 through a rotating shaft 15, and a torsion spring 16 is arranged on the rotating shaft 15; under the action of the protective blocks 11, in the initial state, the two protective blocks 11 are flush with each other under the action of the torsion spring 16, and the mouth of the card slot 12 can be closed, which can prevent sundries from falling into the card slot 12 when not in use. Moreover, a storage groove 17 corresponding to the protective block 11 is opened on the inner side of the card slot 12. When the mounting base 5 is installed, the two protective blocks 11 are directly pressed by the mounting base 5, so that the two protective blocks 11 are pressed and move into the storage groove 17, making the side surfaces of the protective blocks 11 flush with the side surface of the card slot 12, and a certain acting force is applied to the mounting base 5 under the rebound of the torsion spring 16, indirectly playing a fixing role. Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit them. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the spirit and scope of the technical solutions of the present invention, and they should all be covered by the scope of the claims of the present invention.

Claims

1. A fluorescence detection structure for mounting a centrifuge tube (3), characterized in that, Comprising: A frame body (1) having a receiving cavity (10) and provided with light passing holes (18) perpendicular to each other axially. A detection frame (2) installed in the receiving cavity (10), provided with a card slot (12), and further provided with two first through holes (4) corresponding to the light passing holes (18) and penetrating to the card slot (12). A mounting seat (5) passing through the card slot (12) and having a mounting groove (6) for mounting the centrifuge tube (3). The mounting seat (5) is provided with second through holes (8) respectively corresponding to the two first through holes (4). When the mounting seat (5) and the detection frame (2) are both located in the receiving cavity (10), the light passing holes (18), the first through holes (4) and the second through holes (8) form a light source channel.

2. The fluorescence detection structure according to claim 1, wherein A positioning pin (14) is provided at the top of the mounting seat (5), and a positioning groove (13) is opened in the card slot (12). When the mounting seat (5) is clamped in the card slot (12), the positioning pin (14) passes through the positioning groove (13).

3. A fluorescence detection structure according to claim 1, characterized in that, The edge of the mouth of the receiving cavity (10) has a guiding inclined surface (9).

4. A fluorescence detection structure according to claim 1, wherein The height of the mounting seat (5) is α, and the depth of the card slot (12) is β, and α and β satisfy α > β.

5. A fluorescence detection structure according to claim 4, characterized in that, The top of the mounting seat (5) is recessed inward to form a groove (7).

6. The fluorescence detection structure according to claim 1, wherein The second through holes (8) are four, and the four second through holes (8) are arranged in an array on the circumference of the mounting seat (5).

7. A fluorescence detection structure according to claim 1, characterized in that It further includes two protective blocks (11). The two protective blocks (11) are respectively rotatably arranged at the mouth of the card slot (12) through a rotating shaft (15), and a torsion spring (16) is provided on the rotating shaft (15).

8. A fluorescence detection structure according to claim 7, wherein, A receiving groove (17) corresponding to the protective block (11) is opened on the inner side of the card slot (12).