Multi-stage emulsification vacuum device for producing emulsion preparation

Abstract

The utility model discloses a multi-stage emulsification vacuum device for producing an emulsion preparation, and belongs to the technical field of emulsification equipment. The multi-stage emulsification device comprises a vacuum system, and a first-stage primary emulsification unit, a second-stage emulsification unit and a vacuum emulsification unit which are sequentially communicated, the vacuum system is connected with the vacuum emulsification unit through a vacuum pipeline and is used for vacuumizing the vacuum emulsification unit, and a raw material to be emulsified is emulsified into an emulsion with the particle size of less than 50nm through the multi-stage emulsification unit. Different emulsification units are arranged in a grading manner, the to-be-emulsified raw materials are subjected to grading emulsification layer by layer, the emulsification effect of the emulsification preparation is improved, a matched vacuum system is arranged in the vacuum emulsification unit for vacuumizing treatment, the content of bubbles and oxygen in the emulsion is reduced, the stability of the emulsion preparation is improved, and the quality guarantee period is prolonged. And resource waste caused by arrangement of a plurality of vacuum systems is reduced.

Description

Technical Field

[0001] The utility model belongs to the technical field of emulsification equipment, in particular to a multi-stage emulsification vacuum device for the production of emulsion preparations. Background Art

[0002] Emulsification is the process of one liquid being evenly dispersed in another immiscible liquid in the form of extremely tiny droplets. Emulsification is a liquid-liquid interface phenomenon. Two immiscible liquids, such as oil and water, are separated into two layers in a container, with the oil of lower density in the upper layer and the water of higher density in the lower layer. If an appropriate surfactant is added and stirred vigorously, the oil is dispersed in the water to form an emulsion. This process is called emulsification.

[0003] The emulsifier shears, disperses and impacts the material through the high-speed rotation of the homogenizing head connected to the engine, so that the material becomes more delicate and promotes the mixing of oil and water. It is widely used in ointments and cosmetic creams in the pharmaceutical industry, sauces and juices in the food industry, and the petrochemical industry. However, the traditional emulsification process widely uses one-time emulsification and vacuum operation, which cannot fully emulsify the raw materials to be emulsified.

[0004] After searching, the Chinese utility model patent: a continuous vacuum emulsification device (authorization announcement number: CN207899307U, authorization announcement date: 2018.09.25), the solution includes an oil phase storage tank, a water phase storage tank, a vacuum pump, a main pipe, an emulsification tank, a high-speed shear homogenizer, a stirring device, an emulsification head, a high-pressure homogenizer, a connecting pipe, a discharge valve, a buffer tank, a motor, a stirring rod, an anchor stirring paddle and an impeller stirring paddle; by combining the emulsification pump, the high-pressure homogenizer, the high-speed shear homogenizer, the high-pressure ... The machine combines three emulsification and homogenization technologies into one, and continuously performs three different homogenization and emulsification treatments on the emulsion to make the emulsion fully emulsified. However, this solution emulsifies the liquid phase and the water phase in different storage tanks, and finally mixes them together for emulsification. A vacuum system is set in each storage tank. Although this setting improves the emulsification effect, the final emulsified product is emulsified only once, which may easily result in an unclear emulsification effect. In addition, the setting of multiple vacuum pumps may easily lead to a waste of resources and low efficiency. Utility Model Content

[0005] 1. Technical problems to be solved by the utility model

[0006] The purpose of the utility model is to solve the problem that the existing emulsification device emulsifies the emulsified materials separately and finally emulsifies them together once, which results in insufficient emulsification times for the final emulsified product and cannot achieve the ideal emulsification effect, and the setting of multiple sets of vacuum equipment causes waste of resources.

[0007] 2. Technical solution

[0008] To achieve the above object, the technical solution provided by the present utility model is as follows:

[0009] A multi-stage emulsification vacuum device for the production of an emulsion preparation of the present utility model comprises a vacuum system and a primary emulsification unit, a secondary emulsification unit and a vacuum emulsification unit connected in sequence. The vacuum system is connected to the vacuum emulsification unit through a vacuum pipeline for evacuating the vacuum emulsification unit. The primary emulsification unit processes the raw materials to be emulsified into a first emulsion semi-finished product. The first emulsion semi-finished product is processed into a second emulsion semi-finished product through the secondary emulsification unit, and the second emulsion semi-finished product is processed into an emulsion preparation through the vacuum emulsification unit.

[0010] Preferably, the first emulsion semi-finished product is an emulsion with an emulsification particle size less than 1 μm, the second emulsion semi-finished product is an emulsion with an emulsification particle size less than 100 nm, and the emulsion preparation is an emulsion with an emulsification particle size less than 50 nm.

[0011] Preferably, the primary emulsification unit, the secondary emulsification unit and the vacuum emulsification unit include an emulsification chamber, and a stirring shaft, stirring paddles and a homogenizer arranged on the stirring shaft are provided in the emulsification chamber for emulsifying the emulsion.

[0012] Preferably, the pressure range that the pressurizing unit can apply is 0.1 MPa to 0.9 MPa.

[0013] Preferably, the primary emulsification unit is connected to a feeding unit, and the feeding unit includes a feeding port and a pressurizing unit. The pressurizing unit is used for pressurizing and conveying the raw materials to be emulsified entering from the feeding port.

[0014] Preferably, the pressure range that the pressurizing unit can apply is 0.1 MPa to 0.9 MPa.

[0015] Preferably, the feeding unit is connected to the primary emulsification unit through a double-channel conveying pipeline, and the double-channel conveying pipeline includes a membrane filtration channel and a direct channel.

[0016] Preferably, the vacuum emulsification unit is connected to a discharging unit, and the discharging unit is used for outputting the emulsion preparation.

[0017] 3. Beneficial effects

[0018] Adopting the technical solution provided by the present utility model, compared with the prior art, the following beneficial effects are achieved:

[0019] A multi-stage emulsification vacuum device for the production of emulsion preparations of the present utility model includes a vacuum system and a primary emulsification unit, a secondary emulsification unit, and a vacuum emulsification unit that are connected in sequence. The vacuum system is connected to the vacuum emulsification unit through a vacuum pipeline to evacuate the vacuum emulsification unit. The primary emulsification unit processes the raw materials to be emulsified into a first emulsion semi-finished product. The first emulsion semi-finished product is processed into a second emulsion semi-finished product through the secondary emulsification unit. The second emulsion semi-finished product is processed into an emulsion preparation through the vacuum emulsification unit. The first emulsion semi-finished product is an emulsion with an emulsification particle size less than 1um. The second emulsion semi-finished product is an emulsion with an emulsification particle size less than 100nm. The emulsion preparation is an emulsion with an emulsification particle size less than 50nm. In this application, different emulsification units are set up in stages to perform hierarchical emulsification on the raw materials to be emulsified layer by layer, improving the emulsification effect of the emulsified preparation. A matching vacuum system is set up in the vacuum emulsification unit for vacuum pumping treatment to reduce the content of bubbles and oxygen in the emulsion, improve the stability of the emulsion preparation and extend the shelf life, and reduce the waste of resources caused by setting up multiple vacuum systems. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 FIG. is a schematic diagram of the overall structure of a multi-stage emulsification vacuum device for the production of emulsion preparations of the present utility model.

[0021] Explanation of the reference numerals in the schematic diagram:

[0022] 100, feeding unit; 110, feeding port; 120, pressurizing unit; 130, double-channel conveying pipeline;

[0023] 200, emulsification unit; 210, primary emulsification unit; 220, secondary emulsification unit; 230, vacuum emulsification unit; 300, discharging unit; 400, vacuum system; 500, control system. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0024] In order to enable those skilled in the art to better understand the solution of this application, the technical solutions in the embodiments of this application will be clearly and completely described below in conjunction with the drawings in the embodiments of this application. Obviously, the described embodiments are only a part of the embodiments of this application, rather than all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of this application.

[0025] It should be noted that the terms "first", "second", etc. in the description, claims and above-mentioned drawings of this application are used to distinguish similar objects, and do not necessarily need to be used to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged under appropriate circumstances, so as to implement the embodiments of this application described herein. In addition, the terms "comprising", "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device comprising a series of steps or units does not necessarily have to be limited to those steps or units clearly listed, but may include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0026] In this application, the orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", "front", "rear", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal", etc. is based on the orientation or positional relationship shown in the drawings. These terms are mainly used to better describe this application and its embodiments, and are not used to limit that the indicated devices, elements or components must have a specific orientation, or be constructed and operated in a specific orientation.

[0027] Moreover, in addition to being able to represent an orientation or positional relationship, some of the above terms may also be used to represent other meanings. For example, the term "upper" may also be used to represent a certain attachment relationship or connection relationship in some cases. For those of ordinary skill in the art, the specific meanings of these terms in this application can be understood according to specific circumstances.

[0028] In addition, the terms "installed", "set up", "provided with", "connected", "connected to", "socketed" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, or there can be internal communication between two devices, elements or components. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0029] It should be noted that, without conflict, the embodiments in this application and the features in the embodiments can be combined with each other. The following will refer to the drawings and combine with the embodiments to detail this application.

[0030] Embodiment 1

[0031] Refer to the attached Figure 1, A multi-stage emulsification vacuum device for the production of emulsion preparations in this embodiment is applicable to the application of emulsion preparations in medical, raw and auxiliary materials, pharmaceuticals, and cosmetics. It includes a feeding unit 100, an emulsification unit 200, and a discharging unit 300 that are connected in sequence. The raw materials to be emulsified enter the emulsification unit 200 through the feeding unit 100 for emulsification. The raw materials to be emulsified are emulsified into emulsion preparations that meet the quality requirements in the emulsification unit 200 and enter the next production process through the discharging unit 300. It also includes a vacuum system 400 and a control system 500. The vacuum system 400 is connected to the emulsification unit 200 to create a vacuum environment for the emulsification unit 200, improve the stability of the emulsion preparation, and extend the shelf life. The control system 500 is respectively connected to the feeding unit 100, the emulsification unit 200, the discharging unit 300, and the vacuum system 400 to control various parameters during the emulsification process, such as stirring speed, homogenization speed, vacuum degree, temperature, etc., to ensure the quality and production efficiency of the emulsion preparation.

[0032] The feeding unit 100 includes a feeding port 110 and a pressurizing unit 120. The pressurizing unit 120 is used to pressurize and convey the raw materials to be emulsified that enter the equipment through the feeding port 110. The pressure range that the pressurizing unit 120 can apply is 0.1 MPa to 0.9 MPa. When the pressure that the pressurizing unit 120 can apply is less than 0.1 MPa, the pressure is too small to effectively pressurize and convey the raw materials to be emulsified, affecting the conveying speed. When the pressure that the pressurizing unit 120 can apply is greater than 0.9 MPa, the pressure is too large, which is likely to damage the filter membrane in the equipment. The feeding unit 100 is connected to a dual-channel conveying pipeline 130. The dual-channel conveying pipeline 130 includes a membrane filtration channel and a direct-through channel. The membrane filtration channel is used to filter the raw materials to be emulsified that need to be filtered to remove impurities, so that the raw materials to be emulsified can be better emulsified. The direct-through channel is used to convey general materials and directly enter the next process to reduce the system reaction time.

[0033] The raw materials to be emulsified are transported into the emulsifying unit 200 through the feeding unit 100. The emulsifying unit 200 includes a primary pre-emulsifying unit 210, a secondary emulsifying unit 220, and a vacuum emulsifying unit 230 that are connected in sequence. The primary pre-emulsifying unit 210 is connected to the feeding unit 100 through the dual-channel conveying pipeline 130. The primary pre-emulsifying unit 210 includes an emulsifying chamber and a driving unit. The emulsifying chamber includes a stirring shaft, stirring paddles provided on the stirring shaft, and a homogenizer. The driving unit drives the stirring shaft to rotate, and the stirring shaft drives the stirring paddles and the homogenizer to rotate in the emulsifying chamber, so that the raw materials to be emulsified are processed into the first emulsion semi-finished product; the secondary emulsifying unit 220 includes an emulsifying chamber and a driving unit. The emulsifying chamber includes a stirring shaft, stirring paddles provided on the stirring shaft, and a homogenizer. The driving unit drives the stirring shaft to rotate, and the stirring shaft drives the stirring paddles and the homogenizer to rotate in the emulsifying chamber, so that the first emulsion semi-finished product is processed into the second emulsion semi-finished product; the vacuum emulsifying unit 230 includes an emulsifying chamber, a driving unit, and a vacuum unit. The emulsifying chamber includes a stirring shaft, stirring paddles provided on the stirring shaft, and a homogenizer. The driving unit drives the stirring shaft to rotate, and the stirring shaft drives the stirring paddles and the homogenizer to rotate in the emulsifying chamber, so that the second emulsion semi-finished product is emulsified into an emulsion preparation. The vacuum unit is used to reduce the bubble and oxygen content in the emulsion preparation, improving the final product quality. The first emulsion semi-finished product is an emulsion with an emulsification particle size less than 1um, the second emulsion semi-finished product is an emulsion with an emulsification particle size less than 100nm, and the emulsion preparation is an emulsion with an emulsification particle size less than 50nm.

[0034] The emulsifying unit 200 is connected to a vacuum system 400. Specifically, the vacuum system 400 is connected to the vacuum unit of the vacuum emulsifying unit 230 through a vacuum pipeline. The vacuum pump of the vacuum system 400 evacuates the vacuum emulsifying unit 230 through a vacuum pipeline, reducing the bubble and oxygen content generated during the processing of the emulsion with a particle size less than 100nm in the vacuum emulsifying unit 230, making the bubble and oxygen content in the processed emulsion with an emulsification particle size less than 50nm relatively low, improving the stability of the emulsion preparation and extending the shelf life. The emulsion with an emulsification particle size less than 50nm is the final emulsion preparation that meets the quality requirements. The negative pressure range in which the vacuum system 400 can evacuate the vacuum emulsifying unit 230 is 0.1MPa to 0.9MPa. When the negative pressure of the vacuum emulsifying unit 230 is less than 0.1MPa, it cannot effectively reduce the bubble and oxygen content generated during the processing, affecting the quality of the emulsion preparation. When the negative pressure of the vacuum emulsifying unit 230 is greater than 0.9MPa, the pressure is too high, which is likely to damage the filter membrane in the equipment.

[0035] The discharging unit 300 is connected to the vacuum emulsifying unit 230 for outputting an emulsion preparation meeting the quality requirements to the next process. The discharging unit 300 includes a pressure pump and a discharging port. The pressure pump pressurizes the emulsion meeting the quality requirements conveyed in the pipeline and can quickly discharge it through the discharging port.

[0036] The above embodiments only represent certain implementation manners of the present invention, and their descriptions are relatively specific and detailed, but they should not be construed as limitations on the scope of the patent of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present invention, several modifications and improvements can still be made, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the appended claims.

Claims

1. A multi-stage emulsification vacuum device for the production of emulsion preparations, characterized by: The invention comprises a vacuum system (400) and a primary emulsification unit (210), a secondary emulsification unit (220) and a vacuum emulsification unit (230) which are connected in sequence. The vacuum system (400) is connected to the vacuum emulsification unit (230) via a vacuum pipeline for evacuating the vacuum emulsification unit (230). The primary emulsification unit (210) processes the raw materials to be emulsified into a semi-finished emulsion product 1. The semi-finished emulsion product 1 is processed into a semi-finished emulsion product 2 through the secondary emulsification unit (220). The semi-finished emulsion product 2 is processed into an emulsion preparation through the vacuum emulsification unit (230).

2. The multi-stage emulsification vacuum device for producing emulsion preparations according to claim 1, characterized in that: The first emulsion semi-finished product is an emulsion with an emulsion particle size of less than 1 μm, the second emulsion semi-finished product is an emulsion with an emulsion particle size of less than 100 nm, and the emulsion preparation is an emulsion with an emulsion particle size of less than 50 nm.

3. The multi-stage emulsification vacuum device for producing emulsion preparations according to claim 2, characterized in that: The primary emulsification unit (210), the secondary emulsification unit (220) and the vacuum emulsification unit (230) include an emulsification chamber, wherein a stirring shaft and a stirring paddle and a homogenizer arranged on the stirring shaft are provided in the emulsification chamber for emulsifying the emulsion.

4. The multi-stage emulsification vacuum device for producing emulsion preparations according to claim 3, characterized in that: The negative pressure range of the vacuum emulsification unit (230) is 0.1 MPa to 0.9 MPa.

5. The multi-stage emulsification vacuum device for producing emulsion preparations according to claim 4, characterized in that: The primary emulsification unit (210) is connected to a feeding unit (100), and the feeding unit (100) includes a feeding port (110) and a pressurizing unit (120). The pressurizing unit (120) is used to pressurize and transport the raw materials to be emulsified entering from the feeding port (110).

6. The multi-stage emulsification vacuum device for producing emulsion preparations according to claim 5, characterized in that: The pressure range that can be applied by the pressurizing unit (120) is 0.1 MPa to 0.9 MPa.

7. The multi-stage emulsification vacuum device for producing emulsion preparations according to claim 6, characterized in that: The feeding unit (100) is connected to the primary emulsification unit (210) via a dual-channel delivery pipeline (130), and the dual-channel delivery pipeline (130) includes a membrane filtration channel and a straight-through channel.

8. The multi-stage emulsification vacuum device for producing emulsion preparations according to claim 7, characterized in that: The vacuum emulsification unit (230) is connected to a discharge unit (300), and the discharge unit (300) is used to output the emulsion preparation.

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