Centrifugal equipment for preparing PRP

By combining the refrigeration device and the centrifugal device, it provides a low-temperature environment and insulation measures, solving the problem of the use of anticoagulants in PRP preparation, ensuring the stability and effect of PRP, and making it convenient for clinical application.

CN223184722UActive Publication Date: 2025-08-05LONGGANG HUIKANG HOSPITAL
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Patent Information

Application Number
CN202421417203.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Priority Date
2023-07-21
Filing Date
2024-06-20
Publication Date
2025-08-05
Estimated Expiration
2034-06-20

AI Technical Summary

Technical Problem

The prior art uses anticoagulants in the preparation of PRP to cause damage to blood components, affecting the use effect, and PRP is prone to coagulation and deterioration at room temperature.

Method used

The refrigeration device and the centrifugal device are combined to form an adjacent first cooling space and a second cooling space, providing a low temperature environment and insulated through the secondary cooling module, avoiding the use of anticoagulants, ensuring that PRP is prepared and stored at low temperatures.

Benefits of technology

It realizes the low-temperature preparation and storage of PRP, avoids coagulation and deterioration, improves the effectiveness of PRP, and simplifies the operation process, making it easier for clinical application.

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Abstract

The utility model relates to the technical field of medical instruments, in particular to centrifugal equipment for preparing PRP. The centrifugal equipment comprises a refrigerating device, a centrifugal device and an auxiliary cooling module, a first cooling space and a second cooling space which are adjacently arranged are formed in the refrigerating device, the first cooling space provides a low-temperature environment for the centrifugal device, and the refrigerating device and the centrifugal device are combined to cool the centrifugal device. The PRP prepared by the centrifugal device can be kept at a low temperature to avoid solidification and deterioration of the PRP, use of an anticoagulant is avoided, the use effect of the PRP is improved, meanwhile, the auxiliary cooling module is arranged in the second cooling space adjacent to the first cooling space, when the centrifugal device is used for repeatedly opening and closing the cover body to take blood, temperature rise in the first cooling space is avoided, and the service life of the PRP is prolonged. And the low-speed low-temperature centrifugal machine only needs to open the cover body and put the blood reagent tube into the centrifugal device, so that the low-speed low-temperature centrifugal machine is simple and convenient to operate and convenient for clinical application.
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Description

[0001] This utility model claims the priority of a Chinese patent application titled "A Low-temperature Centrifugal Refrigeration Device for Medical Clinical Treatment" with the application number 202321930629.7 and filed on July 21, 2023. The content of the above Chinese patent application is hereby incorporated into this application by reference. Technical Field

[0002] This utility model relates to the technical field of medical devices, and particularly to a centrifugal device for PRP preparation. Background Art

[0003] Platelet-rich plasma (PRP), platelet-poor plasma (PPP), and platelet-rich fibrin (PRF) are all extracted from blood. Among them, PRP is highly concentrated platelets and rich in various growth factors. It can promote cell proliferation and differentiation, and PRP has been gradually applied to tissue repair in the fields of stomatology, plastic surgery, orthopedics, otolaryngology, neurosurgery, etc.

[0004] Since PRP is easily activated at room temperature, coagulates quickly and is prone to deterioration, most of the existing PRP preparations are obtained by centrifugation after adding anticoagulants to venous blood at room temperature. However, adding anticoagulants to blood will destroy the physical and chemical properties of blood components, resulting in certain side effects of the injected PRP and thus reducing the use effect of PRP. Content of the Utility Model

[0005] (I) Technical Problems to be Solved

[0006] In view of the above-mentioned drawbacks and deficiencies of the prior art, this utility model provides a centrifugal device for PRP preparation, which solves the technical problem of avoiding the poor use effect caused by the use of anticoagulants during the centrifugation of PRP.

[0007] (II) Technical Solutions

[0008] In order to achieve the above object, the main technical solutions adopted by this utility model include:

[0009] An embodiment of the utility model provides a centrifugal device for PRP preparation, which includes a refrigeration device, a centrifugal device, and a secondary cooling module; the refrigeration device includes a box body, a cover body, and a main cooling module. The cover body covers the box body. The box body is recessed to form adjacent first and second cooling spaces. An accommodation space for accommodating the main cooling module is provided inside the box body. The main cooling module is used to cool the first and second cooling spaces; the centrifugal device is arranged in the first cooling space, and the first cooling space provides a low-temperature environment for the centrifugal device. The secondary cooling module is arranged in the second cooling space to heat-insulate the centrifugal device in the adjacent first cooling space; the centrifugal device is used to centrifuge the blood reagent tubes placed therein to form PRP.

[0010] Preferably, a storage rack is further provided in the second cooling space; the storage rack is used to place the centrifuged blood reagent tubes.

[0011] Preferably, the main cooling module includes a compressor, a condenser, a capillary tube, a cooling pipe, and a fan; the outlet of the compressor is connected to the inlet of the condenser, the outlet of the condenser is connected to the inlet end of the capillary tube, the outlet end of the capillary tube is connected to the inlet of the cooling pipe, and the outlet of the cooling pipe is connected to the inlet of the compressor; the fan is used to dissipate heat from the condenser; the cooling pipe is wound around the outside of the first and second cooling spaces.

[0012] Preferably, the cooling pipe surrounds to form a rectangular structure.

[0013] Preferably, the main cooling module further includes a first control panel and a first controller; the first control panel is arranged at the outer top of the box body; the first controller is electrically connected to the first control panel and the compressor respectively.

[0014] Preferably, the centrifugal device includes a mounting rack and a centrifugal main body; the centrifugal main body is arranged on the mounting rack; the mounting rack divides the interior of the box body to form the first and second cooling spaces.

[0015] Preferably, the mounting rack includes a mounting plate, a counterweight plate, a support rod, and a connecting plate; the centrifugal main body is arranged on the mounting plate; the mounting plate and the counterweight plate are arranged at intervals up and down. The support rod is arranged between the mounting plate and the counterweight plate to support the centrifugal main body on the mounting plate; the connecting plate is arranged on one side of the mounting plate and the counterweight plate, and the connecting plate divides the interior of the box body to form the first and second cooling spaces.

[0016] Preferably, the centrifugal main body includes a centrifugal motor and a centrifugal rotor; the centrifugal motor is arranged on the mounting plate, and the output end of the centrifugal motor is connected to the centrifugal rotor to drive the centrifugal rotor to rotate; multiple centrifugal spaces are provided on the centrifugal rotor to place the blood reagent tubes.

[0017] Preferably, the centrifugation main body further includes a second controller and a second control panel; the second control panel is disposed at the outer top end of the box body; the second controller is electrically connected to the second control panel and the centrifugation motor respectively.

[0018] Preferably, the auxiliary cooling module includes a containing box and a coolant disposed in the containing box.

[0019] (III) Beneficial effects

[0020] The beneficial effects of the present utility model are as follows:

[0021] For the centrifugation equipment for PRP preparation of the present utility model, since it includes a refrigeration device, a centrifugation device and an auxiliary cooling module, by forming adjacent first cooling space and second cooling space inside the refrigeration device, wherein the first cooling space provides a low-temperature environment for the centrifugation device, through the combination of the refrigeration device and the centrifugation device, the PRP prepared by the centrifugation device can be kept at a low temperature to avoid the coagulation and deterioration of PRP and avoid the use of anticoagulants, improving the use effect of PRP. At the same time, since the auxiliary cooling module is disposed in the second cooling space adjacent to the first cooling space, when the centrifugation equipment is used to open and close the cover body multiple times to take blood, the temperature rise in the first cooling space is avoided, further ensuring the low-temperature environment in the first cooling space. And this low-speed low-temperature centrifuge only needs to open the cover body and put the blood reagent tube into the centrifugation device, with simple and convenient operation and being convenient for clinical application. Description of the drawings

[0022] Figure 1 is a schematic structural diagram of the centrifugation equipment for PRP preparation of the present utility model;

[0023] Figure 2 is a schematic internal structure diagram of the box body;

[0024] Figure 3 is a schematic structural diagram of the centrifugation device;

[0025] Figure 4 is a schematic structural diagram of the cooling pipe.

[0026]

Description of the attached drawing reference numerals

[0027] 1: Refrigeration device; 11: Box body; 12: Cover body; 13: First cooling space; 14: Second cooling space; 15: First control panel; 16: Cooling pipe;

[0028] 2: Centrifugation device; 21: Mounting rack; 211: Mounting plate; 212: Counterweight plate; 213: Support rod; 214: Connecting plate; 215: Suction cup; 22: Centrifugation main body; 221: Centrifugation motor; 222: Centrifugation rotor; 223: Second control panel. Detailed implementation manners

[0029] In order to better explain the present utility model for easy understanding, the present utility model will be described in detail below in conjunction with the accompanying drawings through specific embodiments.

[0030] As Figure 1 shown, this embodiment provides a centrifugation device for PRP preparation. The centrifugation device includes a refrigeration device 1, a centrifugation device 2, and a secondary cooling module (not shown). Among them, the refrigeration device 1 includes a box body 11, a cover body 12, and a main cooling module. The cover body 12 covers the box body 11. The box body 11 is recessed to form adjacent first cooling space 13 and second cooling space 14. An accommodation space for accommodating the main cooling module is provided inside the box body 11. The main cooling module is used to cool the first cooling space 13 and the second cooling space 14. The centrifugation device 2 is disposed in the first cooling space 13. The first cooling space 13 provides a low-temperature environment for the centrifugation device 2. The secondary cooling module is disposed in the second cooling space 14 to maintain the low-temperature environment of the centrifugation device 2 in the adjacent first cooling space 13. The centrifugation device 2 is used to centrifuge the blood reagent tubes placed therein to form PRP.

[0031] The centrifugation device for PRP preparation in this embodiment, due to including the refrigeration device 1, the centrifugation device 2, and the secondary cooling module, by forming adjacent first cooling space 13 and second cooling space 14 inside the refrigeration device 1, where the first cooling space 13 provides a low-temperature environment for the centrifugation device 2. Through the combination of the refrigeration device 1 and the centrifugation device 2, the PRP prepared by the centrifugation device 2 can be kept at a low temperature to avoid the coagulation and deterioration of PRP and avoid the use of anticoagulants, improving the use effect of PRP. At the same time, since the secondary cooling module is disposed in the second cooling space 14 adjacent to the first cooling space 13, when the cover body 12 of the centrifugation device is opened and closed multiple times to take blood, the temperature rise in the first cooling space 13 is avoided, further ensuring the low-temperature environment in the first cooling space 13. And this low-speed low-temperature centrifuge only needs to open the cover body 12 and put the blood reagent tubes into the centrifugation device 2, which is simple and convenient to operate and is convenient for clinical application.

[0032] A storage rack (not shown) is also provided in the second cooling space 14. The storage rack is used to place the centrifuged blood reagent tubes, that is, the PRP reagent tubes, for convenient storage of PRP.

[0033] In the actual application process, the main cooling module includes a compressor, a condenser, a capillary tube, a cooling pipe 16, a fan, a first control panel 15 and a first controller. The outlet of the compressor is connected to the inlet of the condenser, the outlet of the condenser is connected to the inlet end of the capillary tube, the outlet end of the capillary tube is connected to the inlet of the cooling pipe 16, and the outlet of the cooling pipe 16 is connected to the inlet of the compressor. The fan is used to dissipate heat from the condenser, and the cooling pipe 16 is wound around the outside of the first cooling space 13 and the second cooling space 14. Among them, the first control panel 15 is arranged at the outer top end of the box body 11, and the first controller is electrically connected to the first control panel 15 and the compressor respectively. The mechanical energy generated by the compressor is controlled by the first controller, and then the temperature provided by the main cooling module is controlled. In this embodiment, the temperatures of the first cooling space 13 and the second cooling space 14 are -4°C to -20°C, preferably -15°C to -20°C.

[0034] The refrigeration principle is as follows: The normal-temperature gaseous refrigerant is compressed into a high-temperature gaseous refrigerant by the compressor, undergoes heat release and condensation through the condenser, is dried and purified through the drying filter, vaporizes by absorbing heat through the capillary tube, and continuously cools the first cooling space 13 and the second cooling space 14 through the cooling pipe 16 wound around the outside of the first cooling space 13 and the second cooling space 14. After heat exchange, the refrigerant re-enters the compressor and circulates like this, so that the sample in the first cooling space 13 is frozen while undergoing high-speed centrifugation. It should be noted that the refrigeration principle and structure are both prior arts and will not be described in detail here again.

[0035] As Figure 2 shown, the centrifugal device 2 includes a mounting frame 21 and a centrifugal main body 22. The centrifugal main body 22 is arranged on the mounting frame 21, and the mounting frame 21 divides the interior of the box body into a first cooling space 13 and a second cooling space 14. As Figure 4 shown, to make the temperatures in the first cooling space 13 and the second cooling space 14 more uniform, the first cooling space 13 and the second cooling space 14 form a rectangular space, and the matching cooling pipes 16 surround to form a rectangular structure.

[0036] As Figure 3As shown, the mounting bracket 21 includes a mounting plate 211, a counterweight plate 212, a support rod 213, a connecting plate 214, and a suction cup 215. The centrifugal main body 22 is disposed on the mounting plate 211. The mounting plate 211 and the counterweight plate 212 are arranged at an interval up and down. The support rod 213 is disposed between the mounting plate 211 and the counterweight plate 212 to support the centrifugal main body 22 on the mounting plate 211. The connecting plate 214 is disposed on one side of the mounting plate 211 and the counterweight plate 212. The connecting plate 214 divides the interior of the box body into a first cooling space 13 and a second cooling space 14. Among them, 4 suction cups 215 are arranged in a rectangular distribution below the counterweight plate 212. The suction cups 215 can adsorb on the bottom wall of the first cooling space 13 to make the centrifugal device 2 on the mounting bracket 21 more stable during operation. It should be noted that the auxiliary cooling module includes a receiving box and a coolant disposed in the receiving box. The receiving box is in contact with the connecting plate 214.

[0037] As Figure 3 shown, the centrifugal main body 22 includes a centrifugal motor 221, a centrifugal rotor 222, a second controller, and a second control panel 223. The centrifugal motor 221 is disposed on the mounting plate 211. The output end of the centrifugal motor 221 is connected to the centrifugal rotor 222 to drive the centrifugal rotor 222 to rotate. The centrifugal rotor 222 is provided with a plurality of centrifugal spaces for placing blood reagent tubes.

[0038] The second control panel 223 is disposed at the outer top of the box body 11. The second controller is electrically connected to the second control panel 223 and the centrifugal motor 221 respectively to control the rotation speed of the centrifugal motor 221 through the second controller. In this embodiment, the first controller and the second controller are provided to facilitate controlling the refrigeration device 1 and the centrifugal device 2 through the first control panel and the second control panel respectively, making the operation more convenient and thus facilitating the clinical application and promotion. It should be noted that the control principle belongs to the prior art and will not be described again.

[0039] In the description of the present invention, it should be understood that the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality of" means two or more, unless otherwise specifically defined.

[0040] In the present utility model, unless otherwise clearly specified or limited, terms such as "installation", "connection", "attachment", "fixation", etc. shall be construed in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral one; it may be a mechanical connection or an electrical connection; it may be a direct connection or an indirect connection through an intermediate medium; it may be the internal communication between two components or the interaction relationship between two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0041] In the present utility model, unless otherwise clearly specified or limited, when the first feature is "above" or "below" the second feature, it may be that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, when the first feature is "above", "over" and "on top of" the second feature, it may be that the first feature is directly above or obliquely above the second feature, or simply means that the horizontal height of the first feature is higher than that of the second feature. When the first feature is "below", "beneath" and "underneath" the second feature, it may be that the first feature is directly below or obliquely below the second feature, or simply means that the horizontal height of the first feature is lower than that of the second feature.

[0042] In the description of this specification, the descriptions of terms such as "one embodiment", "some embodiments", "embodiment", "example", "specific example" or "some examples", etc. mean that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in a suitable manner in any one or more embodiments or examples. In addition, without conflict, those skilled in the art can combine and combine the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0043] Although the embodiments of the present utility model have been shown and described above, it can be understood that the above embodiments are exemplary and should not be construed as limiting the present utility model. Those of ordinary skill in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present utility model.

Claims

1. A centrifugal device for preparing PRP, characterized in that: It comprises a refrigeration device (1), a centrifugal device (2) and a secondary cooling module; The refrigeration device (1) comprises a box body (11), a cover body (12) and a main cooling module, wherein the cover body (12) covers the box body (11), the box body (11) is recessed to form a first cooling space (13) and a second cooling space (14) arranged adjacent to each other, and an accommodating space for accommodating the main cooling module is provided inside the box body (11), and the main cooling module is used to cool the first cooling space (13) and the second cooling space (14); The centrifugal device (2) is arranged in a first cooling space (13), the first cooling space (13) provides a low-temperature environment for the centrifugal device (2), and the auxiliary cooling module is arranged in the second cooling space (14) to keep the centrifugal device (2) in the adjacent first cooling space (13) warm. The centrifugal device (2) is used to centrifuge the blood reagent tube placed therein to form PRP; The centrifugal device (2) comprises a mounting frame (21) and a centrifugal body (22); The centrifugal body (22) is arranged on the mounting frame (21); The auxiliary cooling module includes a containing box and a coolant arranged in the containing box, and the containing box is in contact with a connecting plate (214) of the mounting frame (21).

2. The centrifugal device for preparing PRP according to claim 1, wherein: A storage rack is also provided in the second cooling space (14); The rack is used for placing the centrifuged blood reagent tubes.

3. The centrifugal device for preparing PRP according to claim 2, wherein: The main cooling module includes a compressor, a condenser, a capillary tube, a cooling tube (16) and a fan; The outlet of the compressor is communicated with the inlet of the condenser, the outlet of the condenser is communicated with the inlet end of the capillary tube, the outlet end of the capillary tube is communicated with the inlet end of the cooling tube (16), and the outlet of the cooling tube (16) is communicated with the inlet end of the compressor; The fan is used to dissipate heat from the condenser; The cooling pipe (16) is wound around the outside of the first cooling space (13) and the second cooling space (14).

4. The centrifugal device for preparing PRP according to claim 3, wherein: The cooling pipe (16) is surrounded to form a rectangular structure.

5. The centrifugal device for preparing PRP according to claim 3, wherein: The main cooling module further comprises a first control panel (15) and a first controller; The first control panel (15) is arranged on the external top end of the box; The first controller is electrically connected to the first control panel (15) and the compressor respectively.

6. The centrifugal device for preparing PRP according to claim 1, wherein: The mounting frame (21) divides the interior of the box (11) into the first cooling space (13) and the second cooling space (14).

7. The centrifugal device for preparing PRP according to claim 6, wherein: The mounting frame (21) comprises a mounting plate (211), a counterweight plate (212), a support rod (213) and the connecting plate (214); The centrifugal body (22) is arranged on the mounting plate (211); The mounting plate (211) and the counterweight plate (212) are spaced apart from each other, and the support rod (213) is arranged between the mounting plate (211) and the counterweight plate (212) to support the centrifugal body (22) on the mounting plate (211); The connecting plate (214) is arranged on one side of the mounting plate (211) and the counterweight plate (212), and the connecting plate (214) divides the interior of the box (11) into the first cooling space (13) and the second cooling space (14).

8. The centrifugal device for preparing PRP according to claim 7, wherein: The centrifugal body (22) includes a centrifugal motor (221) and a centrifugal rotor (222); The centrifugal motor (221) is arranged on the mounting plate (211), and the output end of the centrifugal motor (221) is connected to the centrifugal rotor (222) to drive the centrifugal rotor (222) to rotate; The centrifugal rotor (222) is provided with a plurality of centrifugal spaces for placing the blood reagent tubes.

9. The centrifugal device for preparing PRP according to claim 8, wherein: The centrifugal body (22) further includes a second controller and a second control panel (223); The second control panel (223) is arranged on the external top end of the box; The second controller is electrically connected to the second control panel (223) and the centrifugal motor (221) respectively.