Valve device and chromatography experiment equipment with same

Abstract

The utility model provides a valve device and chromatography experiment equipment with the valve device, the valve device comprises a first valve body and a second valve body, the first valve body is provided with a first opening, a second opening, an inflow opening and a backflow opening, the first valve body is internally provided with a first channel, a second channel, a third channel and a fourth channel, the first channel communicates with the first connector and the first opening, the second channel communicates with the second connector and the second opening, the third channel communicates with the inlet and the inflow opening, and the fourth channel communicates with the outlet and the backflow opening. The second valve body is provided with a first groove-shaped flow channel and a second groove-shaped flow channel; in the length direction, the second groove-shaped flow channel comprises a first groove section and a second groove section which communicate with each other, and when the second valve body is located at the bypass position, the inflow opening directly communicates with the backflow opening through the first groove-shaped flow channel. Only two flow channels are machined in the second matching face of the second valve body, the three functions can be achieved, and the structure of the second valve body is simple.

Description

Technical Field

[0001] The present application relates to the technical field of flow path control, and in particular to a valve device and a chromatography experimental device having the valve device. Background Art

[0002] Chromatographic experimental equipment is an analytical instrument that uses the differences in the physical and chemical properties of the components in a mixture to achieve separation due to the different distribution degrees of each substance through the chromatography column and thus the different flow rates.

[0003] When analyzing samples using chromatography equipment, valves are often required to achieve bypass, forward flow, and reverse flow. While existing valves in chromatography equipment can achieve these three functions, their internal structures are complex, making them difficult to manufacture and, consequently, expensive. This makes them prohibitively expensive for simple chromatography experiments. Utility Model Content

[0004] The purpose of the present application is to provide a valve device that takes into account both experimental accuracy and low use cost, and a chromatography experimental device having the valve device.

[0005] The present application provides a valve device, comprising:

[0006] A first valve body, comprising a connecting surface and a first mating surface, wherein the connecting surface is provided with an inlet, an outlet, a first interface and a second interface, and the first mating surface is provided with a first opening, a second opening, an inflow opening and a return opening, wherein the interior of the first valve body has a first channel, a second channel, a third channel and a fourth channel, wherein the first channel communicates with the first interface and the first opening, the second channel communicates with the second interface and the second opening, the third channel communicates with the inlet and the inflow opening, and the fourth channel communicates with the outlet and the return opening;

[0007] The second valve body has a second mating surface that is in sealing rotational engagement with the first mating surface, the second mating surface being provided with a first groove-shaped flow channel and a second groove-shaped flow channel; along the length direction, the second groove-shaped flow channel includes a first groove section and a second groove section that are connected, and the second valve body is rotatable relative to the first valve body to a forward flow position, a reverse flow position, and a bypass position;

[0008] When the second valve body is located at the bypass position, the inlet opening is directly connected to the return opening through the first groove-shaped flow channel;

[0009] When the second valve body is located at the positive flow position, the inflow opening is connected to the first opening through the first groove-shaped flow channel, and the second opening is connected to the return flow opening through the first groove section;

[0010] When the second valve body is located at the reverse flow position, the inflow opening is connected to the second opening through the first groove-shaped flow channel, and the first opening is connected to the reverse flow opening through the second groove section.

[0011] For relatively simple chromatography experimental equipment, such as a single chromatography column, the valve device provided by this application can meet the functional requirements of forward flow, reverse flow, and bypass. In the embodiment of this application, the second valve body is machined with only two flow channels on the second mating surface to achieve the above three functions. The second valve body has a relatively simple structure and a relatively simple processing technology, and accordingly, the cost of use is relatively low, achieving the goal of balancing experimental accuracy and low cost of use.

[0012] In one example, the central axis of the first valve body and the central axis of the second valve body are coaxially arranged, the second valve body rotates relative to the first valve body around the central axis, the first groove-shaped flow channel and the inflow opening both extend to the central axis, and the central axis passes through the first flow channel and the inflow opening.

[0013] In one example, the end of the first slot-shaped flow channel away from the central axis, the relatively distant ends of the first slot segment and the second slot segment, the connection position of the first slot segment and the second slot segment, the first opening, the second opening and the return opening are all at the same distance from the central axis.

[0014] In one example, the first groove-shaped flow channel is a radially extending straight groove segment;

[0015] Alternatively or alternatively, the first slot segment is a straight slot segment or an arc-shaped slot segment;

[0016] Alternatively or alternatively, the second slot segment is a straight slot segment or an arcuate slot segment.

[0017] In one example, the first groove-shaped flow channel passes through the central axis of the second valve body, and the connection position of the first groove section and the second groove section is located on the extension line of the first groove-shaped flow channel.

[0018] In one example, when the first slot segment and the second slot segment are both straight slot segments, the angle between the first slot segment and the second slot segment ranges from 80° to 100°;

[0019] Alternatively, the first slot section and the second slot section are perpendicular.

[0020] In one example, the circumferential outer dimension of the first valve body is larger than the circumferential outer dimension of the second valve body, the first mating surface is at least a partial area of the end surface of the first valve body facing the second valve body, and the second mating surface is the end surface of the second valve body facing the first valve body. The second valve body rotates relative to the first valve body around the central axis, and the first mating surface and the second mating surface are both perpendicular to the central axis.

[0021] In one example, the first valve body includes an outer peripheral wall, and a first end wall and a second end wall connected to both ends of the outer peripheral wall, the first end wall faces the second valve body, the first mating surface is located on the first end wall, and the inlet, outlet, first interface and second interface are located on the second end wall or / and the outer peripheral wall.

[0022] In one example, the inlet, the outlet, the first interface, and the second interface are located in the same cross section, and the inlet, the outlet, the first interface, and the second interface are at the same radial distance from the central axis.

[0023] The present application also provides a chromatography experimental equipment, which also includes a pumping component, a detector, at least one chromatography column and the valve device described in any one of the above items, wherein the first working port of the chromatography column is connected to the first interface, the second working port of the chromatography column is connected to the second interface, the inlet of the first valve body is connected to the pumping component, and the outlet of the first valve body is connected to the detector. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a top view of a chromatography experimental device in a bypass state in one embodiment of the present application;

[0025] Figure 2 for Figure 1 Schematic diagram of the chromatography experimental apparatus shown in the positive flow state;

[0026] Figure 3 for Figure 1 Schematic diagram of the chromatography experimental apparatus shown in the backflow state;

[0027] Figure 4 for Figure 1 3D schematic diagram of the mid-valve device;

[0028] Figure 5 for Figure 4 Another perspective schematic diagram of the valve device shown;

[0029] Figure 6 for Figure 4 A perspective schematic diagram of the valve device shown, wherein the groove-shaped flow channel on the second valve body is not shown;

[0030] Figure 7 for Figure 4A perspective view of a first valve body of the valve device shown;

[0031] Figure 8 for Figure 7 A schematic diagram of a first end surface of the first valve body shown;

[0032] Figure 9 for Figure 4 A three-dimensional schematic diagram of the second valve body in the valve device shown;

[0033] Figure 10 for Figure 9 Top view of .

[0034] in, Figures 1 to 10 middle:

[0035] 1 first valve body; 11 first channel; 11A first interface; 11B first opening; 12 second channel; 12A second interface; 12B second opening; 13 third channel; 13A inlet; 13B inflow opening; 14 fourth channel; 14A outlet; 14B outflow opening;

[0036] 2 second valve body; 21 second mating surface; 22 first groove-shaped flow channel; 23 second groove-shaped flow channel; 231 first groove section; 232 second groove section; 230 connection position; 231A first end portion; 232A second end portion; DETAILED DESCRIPTION

[0037] The inventor of the present application has conducted extensive research on valve devices currently used in chromatography laboratory equipment. The research found that the valve device usually includes a stator and a rotor, which rotate in conjunction with each other. The stator is usually provided with an interface connected to an external pipeline, and the interior of the stator is provided with internal flow channels connected to the various interfaces. The end face of the rotor is also provided with a surface flow channel. By rotating the relative positions of the stator and the rotor, the internal flow channel of the stator and the surface flow channel of the rotor end face can be selectively connected to achieve forward flow, reverse flow and bypass functions. Among them, the simplest structure of the current rotor is that three independent flow channels are provided on the end face. How to further simplify the structure of the valve device and further reduce the cost of using the valve device is the main technical issue that this application focuses on.

[0038] To help those skilled in the art better understand the technical solution of this application, the following is a further detailed description of this application in conjunction with the accompanying drawings and specific embodiments. This article uses the valve device applied to chromatography laboratory equipment to achieve forward flow, reverse flow, and bypass as an example to introduce the technical solution and technical effects. Those skilled in the art should understand that the valve device of this application can also be applied to other systems.

[0039] Please refer to Figures 1 to 10 , Figure 1 This is a top view of a chromatography experimental device in a bypass state in one embodiment of the present application; Figure 2 for Figure 1 Schematic diagram of the chromatography experimental apparatus shown in the positive flow state; Figure 3 for Figure 1 Schematic diagram of the chromatography experimental apparatus shown in the backflow state; Figure 4 for Figure 1 3D schematic diagram of the mid-valve device; Figure 5 for Figure 4 Another perspective schematic diagram of the valve device shown; Figure 6 for Figure 4 A perspective schematic diagram of the valve device shown, wherein the groove-shaped flow channel on the second valve body is not shown; Figure 7 for Figure 4 A perspective view of a first valve body of the valve device shown; Figure 8 for Figure 7 A schematic diagram of a first end surface of the first valve body shown; Figure 9 for Figure 4 A three-dimensional schematic diagram of the second valve body in the valve device shown; Figure 10 for Figure 9 Top view of .

[0040] The present embodiment provides a chromatography experimental device, comprising at least a detector 400, a pumping component 300, a chromatography column 200, and a valve device 100. The detector 400 is primarily used to detect and record various compounds flowing out of the chromatography column and to perform quantitative or qualitative analysis on these compounds. Common detectors include ultraviolet detectors, fluorescence detectors, conductivity detectors, and the like.

[0041] The chromatography column 200 is made of a tube with a stationary phase coated on its inner wall. Depending on the experimental requirements, the column can be divided into adsorption columns, ion exchange columns, gel filtration columns, etc. Its function is to gradually separate the mixture to be separated through the stationary phase layer.

[0042] When a liquid such as a solvent or solution flows through the chromatography column 200, it contacts the stationary phase and gradually removes the mixture adsorbed or reacted on the stationary phase. The mixture is then separated based on its affinity with the solvent or solution. Common solvents or solutions include water, methanol, chloroform, etc.

[0043] The pumping component 300 mainly provides the flow power of liquids such as solvents or solutions in the chromatography experimental device. The pumping component 300 can be a liquid pump, or of course, other components that can provide flow power.

[0044] This application does not describe the specific structures of the detector 400 , the chromatography column 200 and the pumping component 300 , but this does not hinder those skilled in the art from understanding the technical solution of this document.

[0045] The valve device 100 in the embodiment of the present application includes a first valve body 1 and a second valve body 2 that are capable of relative rotation. That is, the second valve body 2 is capable of rotating about their central axis. Typically, the second valve body can be partially located within the first valve body 1, i.e., the first valve body 1 has an inner cavity, and the second valve body 2 can be partially or entirely located within the inner cavity of the first valve body 1. The first valve body 1 and the second valve body 2 rotate in circumferential coordination. The outer shapes of the first valve body 1 and the second valve body 2 can be designed as needed and are not specifically limited herein.

[0046] Of course, the second valve body 2 may also be completely located outside the first valve body 1 . The drawings of this application show that the second valve body 2 is completely located outside the first valve body 1 .

[0047] In the embodiment of the present application, the first valve body 1 includes a connection surface and a first mating surface. The connection surface is provided with an inlet 13A, an outlet 14A, a first interface 11A, and a second interface 12A. The inlet 13A of the first valve body 1 is used to connect to the pumping component 300, and the outlet 14A is used to connect to the inlet of the detector 400. The first interface 11A is connected to the first working port of the chromatography column 200, and the second interface 12A is connected to the second working port of the chromatography column 200.

[0048] As can be seen from the above description, the connection surface is mainly used to set up pipeline connection ports with the pumping component 300, the chromatography column 200 and the detector 400. The connection surface is usually the outer surface of the first valve body 1 or an outer surface portion.

[0049] The inlet 13A, outlet 14A, and various interfaces can be located at appropriate locations on the connection surface of the first valve body 1, as long as they can be reliably connected to other components. To ensure the reliability of the connection pipeline and improve the connection efficiency, the interfaces of each interface unit can be marked. In this application, the first valve body 1 is equivalent to the stator, and the second valve body 2 rotates relative to the first valve body 1, and the second valve body 2 is equivalent to the rotor.

[0050] The first mating surface is provided with a first opening 11B, a second opening 12B, an inflow opening 13B, and a return opening 14B. The first opening 11B, the second opening 12B, the inflow opening 13B, and the return opening 14B can all be circular holes, but they can also be square, triangular, or other shaped openings. The interior of the first valve body comprises a first channel 11, a second channel 12, a third channel 13, and a fourth channel 14. The first channel 11 connects the first interface 11A and the first opening 11B, the second channel 12 connects the second interface 12A and the second opening 12B, the third channel 13 connects the inlet 13A and the inflow opening 13B, and the fourth channel 14 connects the outlet 14A and the return opening 14B. In other words, one opening on the first mating surface connects to the interface, inlet 13A, or outlet 14A on the connecting surface via a channel. As shown in the figure, the internal channels of the first valve body 1 can have the same or different shapes.

[0051] The second valve body 2 has a second mating surface 21 that is in sealed rotational engagement with the first mating surface 21. The second mating surface 21 is provided with a first slot-shaped flow channel 22 and a second slot-shaped flow channel 23. The first slot-shaped flow channel 22 and the second slot-shaped flow channel 23 are relatively independent and disconnected from each other. The slots of the first slot-shaped flow channel 22 and the second slot-shaped flow channel 23 face the first valve body 1.

[0052] Along the length direction, the second groove-shaped flow channel 23 includes a first groove section 231 and a second groove section 232 that are connected. The second valve body 2 can rotate relative to the first valve body 1 to a forward flow position, a reverse flow position, and a bypass position.

[0053] Please refer to Figure 1 When the second valve body 2 is in the bypass position, the inflow opening 13B is directly connected to the return opening 14B through the first groove-shaped flow channel 22; the flow direction of the fluid is: pumping component → 13A → 13B → 22 → 14B → 14A;

[0054] Please refer to Figure 2 When the second valve body 2 is in the positive flow position, the inflow opening 13B is connected to the first opening 11B through the first groove-shaped flow channel 22, and the second opening 12B is connected to the return opening 14B through the first groove section 231; the fluid flow direction is: pumping component → 13A → 13B → 22 → 11B → 11A → first working port of the chromatography column → second working port of the chromatography column → 12A → 12B → 231 → 14B → 14A;

[0055] Please refer to Figure 3 When the second valve body 2 is in the reverse flow position, the inflow opening 13B is connected to the second opening 12B through the first flow channel, and the first opening 11B is connected to the reflux opening 14B through the second groove section 232; the flow direction of the fluid is: pumping component → 13A → 13B → 22 → 12B → 12A → second working port of the chromatography column → first working port of the chromatography column → 11A → 11B → 232 → 14B → 14A.

[0056] For relatively simple chromatography experimental equipment, such as a single chromatography column 200, the valve device 100 provided herein can meet the functional requirements of forward flow, reverse flow, and bypass. The second mating surface of the second valve body 2 in this embodiment of the present application is machined with only two flow channels to achieve the aforementioned three functions. The second valve body 2 has a relatively simple structure and a relatively simple manufacturing process, resulting in relatively low operating costs.

[0057] In the embodiment of the present application, the central axes of the first valve body 1 and the second valve body 2 are coaxially arranged, and the second valve body 2 rotates relative to the first valve body 1 around the central axis. The inflow opening 13B is located at the center position of the end face of the first valve body 1 facing the second valve body 2, that is, the inflow opening 13B is located at the center position of the lower end face of the second valve body 2. In other words, the central axis passes through the inflow opening 13B. The first slot-shaped flow channel 22 is a long strip flow channel, and the inner end of the first slot-shaped flow channel 22 extends to the center position of the second valve body 2, that is, the central axis also passes through the first slot-shaped flow channel 22. In this way, the first slot-shaped flow channel 22 and the inflow opening 13B always have an overlapping area at the center position of rotation. No matter how the second valve body 2 rotates, the inflow opening 13B is always connected to the first flow channel.

[0058] The overlapping area between the inflow opening 13B and the first groove-shaped flow channel 22 can be determined according to the actual flow rate, as long as it can meet the use requirements.

[0059] In the embodiment of the present application, the end of the first slot-shaped flow channel 22 away from the central axis, the ends of the first slot segment 231 and the second slot segment 232 relatively away (the first end 231A and the second end 232A in the figure), the connection position 230 of the first slot segment 231 and the second slot segment 232, the first opening 11B, the second opening 12B and the return opening 14B are all at the same distance from the central axis, as shown in FIG. Figure 8 As shown, the centers of the first opening 11B, the second opening 12B, and the return opening 14B are all located on a circle with a diameter R. This reduces the need for the slot-shaped flow channel to be too long, preventing fluid from being retained in the outer end sections of the slot-shaped flow channel (the relatively distant ends mentioned above), and also helps prevent liquid leakage.

[0060] The second slot-shaped flow channel 23 can be roughly V-shaped or arc-shaped, that is, the first slot section 231 and the second slot section 232 form a V-shaped or arc-shaped structure, and the lengths of the first slot section 231 and the second slot section 232 can be roughly the same. When the first slot section 231 and the second slot section 232 are both straight slot sections, the angle between the first slot section 231 and the second slot section 232 is roughly in the range of 80° to 100°, such as 80°, 85°, 90°, 95° or 100°. Of course, it can also be other values within the range of 80° to 100°, which are not listed here. The accompanying drawings show an example in which the angle between the first slot section 231 and the second slot section 232 is 90°. In this embodiment, when rotating from the positive flow position to the reverse flow position, the second valve body 2 only needs to rotate 180°, which is relatively fast.

[0061] In the embodiment of the present application, the first slot-shaped flow channel 22 is a radially extending straight slot segment, which has a simple structure and a simple processing technology. Of course, one or both of the first slot segment 231 and the second slot segment 232 can also be a straight slot segment.

[0062] The first slot-shaped flow channel 22 passes through the central axis of the second valve body 2, and the connection point 230 between the first slot section 231 and the second slot section 232 is located on the extension line of the first slot-shaped flow channel 22. The first slot-shaped flow channel 22 and the second slot-shaped flow channel 23 are relatively evenly arranged on the end surface of the second valve body 2, which helps to improve the overall strength of the second valve body 2.

[0063] In the embodiment of the present application, the circumferential outer dimensions of the first valve body 1 are greater than those of the second valve body 2. In a plane perpendicular to the central axis, the projection of the second valve body 2 can be completely located within the projection of the first valve body 1. The first valve body 1 and the second valve body 2 can both be cylindrical. Because the first valve body 1 needs to be connected to an external pipeline, the diameter of the first valve body 1 is greater than the diameter of the second valve body 2. Since the diameter of the first valve body 1 is relatively large, and the second valve body 2 does not need to be connected to an external pipeline, the diameter of the second valve body 2 can be relatively small, which can further reduce the cost of the valve device.

[0064] Therefore, the first matching surface is at least a portion of the end surface of the first valve body 1 facing the second valve body 2. Figure 8 The first mating surface is shown as the end surface of a circle with a radius R1 on the first end wall 17 of the first valve body 1. The second mating surface is the end surface of the second valve body 2 facing the first valve body 1. The second valve body 2 rotates relative to the first valve body 1 around the central axis, and both the first mating surface and the second mating surface are perpendicular to the central axis.

[0065] The first valve body 1 can be cylindrical, or of course can be other shapes. The first valve body 1 includes an outer peripheral wall 16, and a first end wall 17 and a second end wall 15 connected to both ends of the outer peripheral wall 16. The first end wall 17 faces the second valve body 2, the first mating surface is located on the first end wall 17, and the inlet 13A, the outlet 14A, the first interface 11A and the second interface 12A are located on the second end wall or / and the outer peripheral wall. The inlet 13A, the outlet 14A, the first interface 11A and the second interface 12A are arranged at reasonable positions on the outer surface of the first valve body 1 based on the convenience of connection. The figure shows that the inlet 13A, the outlet 14A, the first interface and the second interface are arranged at the position where the second end wall 15 and the outer peripheral wall 16 are connected.

[0066] The inlet 13A, the outlet 14A, the first interface 11A and the second interface 12A are located in the same cross section and are at the same radial distance from the central axis, which facilitates processing.

[0067] The above is only a preferred embodiment of the present application. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present application. These improvements and modifications should also be regarded as the scope of protection of the present application.

Claims

1. A valve device, characterized in that include: A first valve body, comprising a connecting surface and a first mating surface, wherein the connecting surface is provided with an inlet, an outlet, a first interface and a second interface, and the first mating surface is provided with a first opening, a second opening, an inflow opening and a return opening, wherein the interior of the first valve body has a first channel, a second channel, a third channel and a fourth channel, wherein the first channel communicates with the first interface and the first opening, the second channel communicates with the second interface and the second opening, the third channel communicates with the inlet and the inflow opening, and the fourth channel communicates with the outlet and the return opening; The second valve body has a second mating surface that is in sealing rotational engagement with the first mating surface, the second mating surface being provided with a first groove-shaped flow channel and a second groove-shaped flow channel; along the length direction, the second groove-shaped flow channel includes a first groove section and a second groove section that are connected, and the second valve body is rotatable relative to the first valve body to a forward flow position, a reverse flow position, and a bypass position; When the second valve body is located at the bypass position, the inlet opening is directly connected to the return opening through the first groove-shaped flow channel; When the second valve body is located at the positive flow position, the inflow opening is connected to the first opening through the first groove-shaped flow channel, and the second opening is connected to the return flow opening through the first groove section; When the second valve body is located at the reverse flow position, the inflow opening is connected to the second opening through the first groove-shaped flow channel, and the first opening is connected to the reverse flow opening through the second groove section.

2. The valve device according to claim 1, wherein The central axis of the first valve body and the central axis of the second valve body are coaxially arranged, the second valve body rotates relative to the first valve body around the central axis, the first groove-shaped flow channel and the inflow opening both extend to the central axis, and the central axis passes through the first groove-shaped flow channel and the inflow opening.

3. The valve device according to claim 2, wherein The end of the first slot-shaped flow channel away from the central axis, the relatively distant ends of the first slot segment and the second slot segment, the connection position of the first slot segment and the second slot segment, the first opening, the second opening and the return opening are all at the same distance from the central axis.

4. The valve device according to any one of claims 1 to 3, characterized in that The first groove-shaped flow channel is a straight groove segment extending radially; Alternatively or alternatively, the first slot segment is a straight slot segment or an arc-shaped slot segment; Alternatively or alternatively, the second slot segment is a straight slot segment or an arcuate slot segment.

5. The valve device according to claim 4, wherein The first groove-shaped flow channel passes through the central axis of the second valve body, and the connection position of the first groove section and the second groove section is located on the extension line of the first groove-shaped flow channel.

6. The valve device according to claim 5, wherein When the first slot segment and the second slot segment are both straight slot segments, the angle between the first slot segment and the second slot segment is in the range of 80° to 100°; Alternatively, the first slot section and the second slot section are perpendicular.

7. The valve device according to claim 1, wherein The circumferential outer dimension of the first valve body is greater than the circumferential outer dimension of the second valve body, the first mating surface is at least a partial area of the end surface of the first valve body facing the second valve body, and the second mating surface is the end surface of the second valve body facing the first valve body. The second valve body rotates relative to the first valve body around the central axis, and the first mating surface and the second mating surface are both perpendicular to the central axis.

8. The valve device according to claim 1, wherein The first valve body includes an outer peripheral wall, and a first end wall and a second end wall connected to both ends of the outer peripheral wall. The first end wall faces the second valve body, the first mating surface is located on the first end wall, and the inlet, outlet, first interface and second interface are located on the second end wall or / and the outer peripheral wall.

9. The valve device according to claim 8, wherein The inlet, outlet, first interface and second interface are located in the same cross section, and the inlet, outlet, first interface and second interface are at the same radial distance from the central axis of the first valve body.

10. Chromatography experimental equipment, characterized in that, It also includes a pumping component, a detector, at least one chromatography column and the valve device according to any one of claims 1 to 9, wherein the first working port of the chromatography column is connected to the first interface, the second working port of the chromatography column is connected to the second interface, the inlet of the first valve body is connected to the pumping component, and the outlet of the first valve body is connected to the detector.

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