Small molecule active peptide preparation device

Abstract

The utility model belongs to the technical field of active peptide preparation equipment, and particularly relates to a small-molecule active peptide preparation device which comprises a treatment tank, a heating plate fixedly mounted in the treatment tank, a motor and a feeding hopper fixedly connected to the upper end of the treatment tank, stirring blades fixedly connected to the circumferential surface of a rotating rod, two rotating shafts rotationally connected to the interior of the feeding hopper, and a driving motor fixedly connected to the rotating shaft, the circumferential faces of the two rotating shafts are fixedly connected with baffles, the front end and the rear end of the feeding hopper are fixedly connected with fixing shells, the two rotating shafts extend into the two corresponding fixing shells distributed front and back, torsional springs are arranged in the multiple fixing shells, one ends of the torsional springs are fixedly connected with the rotating rods, and the other ends of the torsional springs are fixedly connected with the inner walls of the fixing shells. The feeding port can be automatically sealed after feeding of the treatment tank is completed, and external impurities are prevented from entering the treatment tank.

Description

Technical Field

[0001] The utility model belongs to the technical field of active peptide preparation equipment, in particular to a small molecule active peptide preparation device. Background Art

[0002] Small molecule active peptides are biochemical substances between amino acids and proteins. They have a smaller molecular weight than proteins but a larger molecular weight than amino acids. They are a fragment of proteins and have the characteristics of simple structure, large molecular weight and high activity. Small molecule peptides can provide the nutrients needed for human growth and development, regulate the physiological functions of various systems and cells in the body, maintain the normal physiological activities of the human nervous, digestive, reproductive, growth, motor metabolism and circulation systems, and have special biological functions. They can prevent and treat thrombosis, hyperlipidemia, hypertension, delay aging, fight fatigue, and enhance the body's immunity.

[0003] At present, the main methods for preparing bioactive peptides include enzymatic hydrolysis, microbial fermentation, chemical synthesis, biological extraction, and genetic recombination. The enzymatic hydrolysis method includes the steps of crushing, enzymatic hydrolysis, filtration, decolorization, and drying. When enzymatic hydrolysis of small molecule active peptide raw materials is performed, alkaline protease needs to be added to the small molecule active peptide raw materials in the processing tank, and the pH value of the small molecule active peptide raw materials needs to be adjusted by heating. For the processing tank used for enzymatic hydrolysis, a feeding port is provided at the top, which needs to be manually closed after feeding. If it is not closed in time, external impurities can easily fall into the processing tank through the feeding port, which is not conducive to the preparation of small molecule active peptides. Summary of the Invention

[0004] The utility model aims to provide a small molecule active peptide preparation device which can automatically close a feeding port of a processing tank after the feeding is completed, thereby preventing external impurities from entering the processing tank.

[0005] To achieve the above-mentioned purpose, the technical solution adopted by the utility model is: to provide a small molecule active peptide preparation device, including a processing tank, a heating plate is fixedly installed inside the processing tank, the upper end of the processing tank is fixedly connected to a motor and a feeding hopper, the processing tank is rotatably connected to a rotating rod, the output shaft end of the motor is fixedly connected to the rotating rod, the circumferential surface of the rotating rod is fixedly connected to a stirring blade, and the stirring blade is located in the processing tank, the inner wall of the feeding hopper is fixedly connected to a partition, the upper end surface of the partition is provided with a feeding hole, the inner rotatable connection of the feeding hopper is connected to two rotating shafts, the circumferential surfaces of the two rotating shafts are fixedly connected to baffles, and the two baffles are located at the lower end of the partition, the front and rear ends of the feeding hopper are fixedly connected to a fixed shell, the two rotating shafts extend respectively into the corresponding two front and rear distributed fixed shells, and are rotatably connected to the corresponding fixed shells, and a torsion spring is provided inside the multiple fixed shells, one end of the torsion spring is fixedly connected to the rotating rod, and the other end of the torsion spring is fixedly connected to the inner wall of the fixed shell.

[0006] Preferably, a discharge pipe and a valve are fixedly connected to the bottom end of the processing tank, and the valve is fixedly connected to the discharge pipe.

[0007] Preferably, a perspective window is provided on the upper end surface of the processing tank.

[0008] Preferably, a connecting pipe is fixedly connected to the upper end of the processing tank, a rubber plug is provided inside the connecting pipe, and a cross cut is opened on the upper end surface of the rubber plug.

[0009] Preferably, a temperature sensor is fixedly installed on the inner top of the processing tank.

[0010] Preferably, two ventilation pipes distributed on the left and right are fixedly connected to the interior of the processing tank, and two support plates are fixedly connected to the circumferential surface of the processing tank. The bottom ends of the two support plates are fixedly connected to electric telescopic rods, and the output ends of the two electric telescopic rods are fixedly connected to closing plates. The two closing plates are respectively located at the lower ends of the two ventilation pipes and are used to close the two ventilation pipes respectively.

[0011] Preferably, the rotating shaft passes through the fixed shell, and a handle is fixedly connected to the circumferential surface of the rotating shaft, and the handle is located at the front end of the fixed shell.

[0012] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0013] When the utility model is used, under the mutual cooperation of the feeding hopper, the fixed shell, the torsion spring, the rotating shaft, the partition and the baffle, when alkaline protease and other raw materials are added to the active peptide raw materials inside the processing tank through the feeding hopper for enzymatic hydrolysis, it is necessary to squeeze the two baffles downward through the feeding pipe filled with alkaline protease, so that the two baffles are turned downward around the rotating shaft, and at the same time the torsion spring is deformed, so that the distance between the two baffles is increased, which makes it easier for the alkaline protease and other raw materials to fall into the processing tank through between the two baffles. After the feeding is completed, the two baffles are automatically turned upward and reset under the action of the torsion spring, and the two baffles close the opening of the feeding hopper to prevent external impurities from entering the processing tank through the feeding hopper and affecting the subsequent preparation of small molecule active peptides. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the embodiments or descriptions of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.

[0015] Figure 1 This is a schematic diagram of the main three-dimensional structure of the utility model;

[0016] Figure 2It is a schematic diagram of the three-dimensional structure of the utility model after partial section from the right side;

[0017] Figure 3 For this utility model Figure 2 Schematic diagram of the enlarged structure at A in the middle;

[0018] Figure 4 This is a schematic diagram of the three-dimensional structure of the utility model after the main view is partially cut away;

[0019] Figure 5 For this utility model Figure 4 Schematic diagram of the enlarged structure at point B in the middle.

[0020] In the figure: 1. Processing tank; 2. Feeding hopper; 3. Motor; 4. Ventilation pipe; 5. Electric telescopic rod; 6. Closing plate; 7. Connecting pipe; 8. Partition; 9. Baffle; 10. Temperature sensor; 11. Stirring blade; 12. Rotating rod; 13. Heating plate; 14. Perspective window; 15. Rubber stopper; 16. Cross cut; 17. Fixed shell; 18. Torsion spring; 19. Rotating shaft; 20. Handle; 21. Valve; 22. Discharge pipe; 23. Support plate. DETAILED DESCRIPTION

[0021] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0022] Please refer to Figure 1-Figure 5Now, an embodiment of the present invention provides a small molecule active peptide preparation device. A small molecule active peptide preparation device includes a processing tank 1, a heating plate 13 is fixedly installed inside the processing tank 1, a motor 3 and a feeding hopper 2 are fixedly connected to the upper end of the processing tank 1, a rotating rod 12 is rotatably connected to the inside of the processing tank 1, the output shaft end of the motor 3 is fixedly connected to the rotating rod 12, the circumferential surface of the rotating rod 12 is fixedly connected to a stirring blade 11, and the stirring blade 11 is located inside the processing tank 1, a partition 8 is fixedly connected to the inner wall of the feeding hopper 2, and a feeding hole is provided on the upper end surface of the partition 8, and the inside of the feeding hopper 2 is rotatably connected to two rotating shafts 19, and the circumferential surfaces of the two rotating shafts 19 are fixed. It is fixedly connected with a baffle 9, and both baffles 9 are located at the lower end of the partition 8, which is used to close the feeding hopper 2. The front and rear ends of the feeding hopper 2 are fixedly connected with a fixed shell 17, and the two rotating shafts 19 extend into the corresponding two front and rear distributed fixed shells 17 respectively, and are rotatably connected with the corresponding fixed shells 17. A torsion spring 18 is provided inside the multiple fixed shells 17, one end of the torsion spring 18 is fixedly connected to the rotating rod 12, and the other end of the torsion spring 18 is fixedly connected to the inner wall of the fixed shell 17; the bottom end of the processing tank 1 is fixedly connected with a discharge pipe 22 and a valve 21, and the valve 21 is fixedly connected to the discharge pipe 22. During operation, the crushed small molecule active peptide raw material is added to the processing tank 1 through the feeding hopper 2, and then the alkaline protease and other materials required for enzymatic hydrolysis are added to the processing tank 1. During the feeding process, the discharge pipe 22 filled with relevant materials will squeeze the two baffles 9 downward, causing the two baffles 9 to flip downward around the rotating shaft 19. At the same time, the opening between the two baffles 9 is expanded, and the torsion spring 18 is deformed, thereby facilitating feeding. After the feeding is completed, the feeding discharge pipe is removed, and the two baffles 9 are flipped upward and reset under the action of the torsion spring 18. The two baffles 9 close the opening of the feeding hopper 2 to prevent external impurities from entering the processing tank 1 through the feeding hopper 2, so as to carry out safe enzymatic hydrolysis of the small molecule active peptide raw material; then control The motor 3 is working, and the output shaft end of the motor 3 drives the rotating rod 12 to rotate, thereby driving the stirring blade 11 to rotate, so that the small molecule active peptide raw material, alkaline protease and other materials are fully stirred and mixed, and then the heating plate 13 is controlled to work, so that the heating is stopped when the temperature inside the processing tank 1 is raised to the temperature required for enzymatic hydrolysis, and the temperature is maintained. The preparation process of different small molecule active peptide raw materials is different, and most of them require heating and enzyme addition for enzymatic hydrolysis; after the enzymatic hydrolysis is completed, the valve 21 is opened, and the small molecule active peptide after enzymatic hydrolysis is discharged through the discharge pipe 22, and then filtered through the filtering equipment, decolorized by the decolorizing equipment, and finally spray-dried by the spray drying equipment, that is, the preparation of the small molecule active peptide is completed. (The filtering equipment, decolorizing equipment and spray drying equipment are not shown in the figure)

[0023] The utility model provides a small molecule active peptide preparation device. Compared with the prior art, under the mutual cooperation of the feeding hopper 2, the fixed shell 17, the torsion spring 18, the rotating shaft 19, the partition 8 and the baffle 9, when alkaline protease and other raw materials are added to the active peptide raw materials inside the processing tank 1 through the feeding hopper 2 for enzymatic hydrolysis, it is necessary to squeeze the two baffles 9 downward through the feeding pipe filled with alkaline protease, so that the two baffles 9 are turned downward around the rotating shaft 19, and at the same time the torsion spring 18 is deformed, so that the distance between the two baffles 9 is increased, which facilitates the alkaline protease and other raw materials to fall into the processing tank 1 through the two baffles 9. After the feeding is completed, the two baffles 9 are automatically turned upward and reset under the action of the torsion spring 18. The two baffles 9 close the opening of the feeding hopper 2 to prevent external impurities from entering the processing tank 1 through the feeding hopper 2 and affecting the subsequent preparation of small molecule active peptides, thereby facilitating the smooth preparation of subsequent small molecule active peptides.

[0024] In another embodiment of the present invention, please refer to Figure 2 The upper end surface of the processing tank 1 is provided with a perspective window 14. When working, the situation inside the processing tank 1 can be conveniently observed through the perspective window 14.

[0025] In another embodiment of the present invention, see Figure 2 and Figure 3 The upper end of the treatment tank 1 is fixedly connected to a connecting pipe 7, and a rubber stopper 15 is provided inside the connecting pipe 7. The upper end surface of the rubber stopper 15 is provided with a cross cut 16. By providing the rubber stopper 15 and the cross cut 16, during operation, on the one hand, it can be used to seal the connecting pipe 7, and on the other hand, the needle of the injection syringe can be inserted through the cross cut 16, and the liquid inside the treatment tank 1 can be extracted using the injection syringe, and the pH value of the enzymatic hydrolysis liquid can be tested using pH test paper to reasonably control the amount of enzyme, temperature and time required in the enzymatic hydrolysis process, thereby facilitating more accurate enzymatic hydrolysis of small molecule active peptides and improving the quality of the prepared product.

[0026] In another embodiment of the present invention, please refer to Figure 4 A temperature sensor 10 is fixedly mounted on the top of the processing tank 1. During operation, the temperature sensor 10 is used to detect the temperature inside the processing tank 1. The temperature sensor 10 is externally connected to an operation panel, and the temperature value sensed by the temperature sensor 10 is displayed on the operation panel so that the operator can better control the temperature of the enzymatic hydrolysis.

[0027] In another embodiment of the present invention, please refer to Figure 1 、 Figure 4 and Figure 5Two ventilation tubes 4, distributed left and right, are fixedly connected to the interior of the treatment tank 1. Two support plates 23 are fixedly connected to the circumference of the treatment tank 1. The bottom ends of the two support plates 23 are fixedly connected to an electric telescopic rod 5. The output ends of the two electric telescopic rods 5 are fixedly connected to a sealing plate 6. The two sealing plates 6 are located directly below the two ventilation tubes 4 and are used to seal the two ventilation tubes 4. When the electric telescopic rods 5 are in operation, they drive the sealing plates 6 to move away from the ventilation tubes 4 or closer to the ventilation tubes 4. When the sealing plates 6 extend into the ventilation tubes 4, they can seal the sealing tubes, preventing heat loss from the treatment tank 1. When the sealing plates 6 are separated from the ventilation tubes 4, they help the treatment tank 1 dissipate heat outward through the ventilation tubes 4.

[0028] In another embodiment of the present invention, see Figure 3 The rotating shaft 19 passes through the fixed shell 17, and the circumferential surface of the rotating shaft 19 is fixedly connected with a handle 20, and the handle 20 is located at the front end of the fixed shell 17. By providing the handle 20, when working, the staff can conveniently control the opening and closing of the baffle 9 by operating the handle 20.

[0029] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A small molecule active peptide preparation device, comprising a processing tank (1), characterized in that: A heating plate (13) is fixedly installed inside the processing tank (1), a motor (3) and a feeding hopper (2) are fixedly connected to the upper end of the processing tank (1), a rotating rod (12) is rotatably connected inside the processing tank (1), an output shaft end of the motor (3) is fixedly connected to the rotating rod (12), a stirring blade (11) is fixedly connected to the circumferential surface of the rotating rod (12), and the stirring blade (11) is located inside the processing tank (1), a partition (8) is fixedly connected to the inner wall of the feeding hopper (2), a discharge hole is opened on the upper end surface of the partition (8), and the internal rotation of the feeding hopper (2) is connected to the inner wall of the feeding hopper (2). Two rotating shafts (19) are connected, and the circumferential surfaces of the two rotating shafts (19) are fixedly connected with baffles (9), and the two baffles (9) are both located at the lower end of the partition (8). The front and rear ends of the feeding hopper (2) are fixedly connected with fixed shells (17). The two rotating shafts (19) respectively extend into the corresponding two fixed shells (17) distributed front and back, and are rotatably connected with the corresponding fixed shells (17). A torsion spring (18) is provided inside the multiple fixed shells (17), one end of the torsion spring (18) is fixedly connected to the rotating rod (12), and the other end of the torsion spring (18) is fixedly connected to the inner wall of the fixed shell (17).

2. The device for preparing small molecule active peptides according to claim 1, wherein: A discharge pipe (22) and a valve (21) are fixedly connected to the bottom end of the processing tank (1), and the valve (21) is fixedly connected to the discharge pipe (22).

3. The device for preparing small molecule active peptides according to claim 1, wherein: The upper end surface of the processing tank (1) is provided with a perspective window (14).

4. The device for preparing small molecule active peptides according to claim 1, wherein: The upper end of the treatment tank (1) is fixedly connected to a connecting pipe (7), a rubber plug (15) is provided inside the connecting pipe (7), and a cross cutout (16) is provided on the upper end surface of the rubber plug (15).

5. The device for preparing small molecule active peptides according to claim 1, characterized in that: A temperature sensor (10) is fixedly installed on the top end of the interior of the processing tank (1).

6. The device for preparing small molecule active peptides according to claim 1, characterized in that: Two ventilation pipes (4) distributed on the left and right are fixedly connected to the interior of the processing tank (1); two support plates (23) are fixedly connected to the circumferential surface of the processing tank (1); the bottom ends of the two support plates (23) are fixedly connected to electric telescopic rods (5); the output ends of the two electric telescopic rods (5) are fixedly connected to closing plates (6); the two closing plates (6) are respectively located at the lower ends of the two ventilation pipes (4) and are respectively used to close the two ventilation pipes (4).

7. The device for preparing small molecule active peptides according to claim 1, characterized in that: The rotating shaft (19) passes through the fixed shell (17); a handle (20) is fixedly connected to the circumferential surface of the rotating shaft (19), and the handle (20) is located at the front end of the fixed shell (17).

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