Bottle airing rack for rapidly drying cell culture bottles

By designing casters and blowing components on the bottle rack to accelerate drying, embedding rubber rings to prevent scratches, and using upper and lower limit holes to prevent collisions, the existing bottle racks are solved to slow drying, difficult to move and scratch collision problems, and improve cell culture efficiency and safety.

CN223216593UActive Publication Date: 2025-08-12ZHAOFENGHUA BIOTECHNOLOGY (FUZHOU) CO LTD
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Patent Information

Application Number
CN202422470865.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-12
Publication Date
2025-08-12
Estimated Expiration
2034-10-12

AI Technical Summary

Technical Problem

The existing bottle drying racks have problems such as long time-consuming drying of cell bottles, not easy to move, and limit holes are easy to scratch the vase walls and cell bottles are easy to collide, which affects cell culture efficiency and safety.

Method used

A bottle drying rack including frame, casters, upper and lower limit holes and blowing components is designed. The cell bottle is quickly dried with clean compressed air, and a rubber ring is embedded at the edge of the limit hole to prevent scratches. The casters are used to facilitate movement, and the upper and lower limit holes are designed to prevent bottle collision.

Benefits of technology

The rapid drying of cell bottles (drying within 15~30 minutes) is achieved, which improves movement convenience and space utilization, avoids scratches and collisions of bottles, and improves work efficiency and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a bottle airing rack for rapidly drying cell culture bottles, which comprises a rack body, the bottom of the rack body is connected with a caster group, the upper end and the lower end of the rack body are respectively provided with a bottle airing mechanism with the same structure, and each bottle airing mechanism comprises an upper disc, a lower disc, an air blowing assembly and a water receiving disc which are sequentially arranged at intervals from top to bottom. The upper disc is provided with upper limiting holes which are arranged in a matrix, the lower disc is respectively provided with lower limiting holes which are coaxially arranged corresponding to the upper limiting holes, the neck parts of the cell bottles are nested in the lower limiting holes, and the bottle bodies of the cell bottles are nested in the upper limiting holes; the air blowing assembly comprises a main air inlet pipe and a branch air inlet pipe, the air inlet end of the main air inlet pipe is connected to a clean compressed air source, one end of the branch air inlet pipe is closed, the other end of the branch air inlet pipe is connected with the main air inlet pipe through a ball valve, a plurality of air blowing pipes blowing air upwards are connected to the branch air inlet pipe, and the air blowing pipes correspond to the lower limiting holes respectively. The bottle airing device can improve the airing speed, prevent bottles from being collided and scratched, and improve the space utilization rate.
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Description

Technical Field

[0001] The utility model relates to the technical field of biological product and vaccine manufacturing equipment, in particular to a bottle drying rack for quickly drying cell culture bottles. Background Art

[0002] Cell culture flasks (hereinafter referred to as cell flasks) are containers widely used in the biopharmaceutical, food, and chemical industries. In the biopharmaceutical field, cell flasks are commonly used for in vitro culture of cells and tissues. They can be divided into glass cell flasks and plastic cell flasks based on their material. Plastic cell flasks are generally disposable and are often used for small-scale cell culture. Some larger, specialized plastic cell flasks can be repeatedly cleaned, sterilized, and recycled, and are often used to store large quantities of antigens and solutions. Glass cell flasks are a commonly used culture medium for cell culture, primarily for step-by-step cell amplification and large-scale culture. They are available in 5L, 10L, and 15L sizes and are reusable.

[0003] The key to successful cell culture is not only the raw materials, culture process, operator quality, and culture environment, but also the cleanliness of the cell flask. A clean flask allows cells to adhere easily and evenly to the flask wall, with consistent growth rates. Conversely, poor cell adhesion can lead to large cell clusters in some areas, with visible uneven cell thickness on the flask wall. Cleaning the flask requires a rigorous series of steps, including scrubbing, alkaline washing, acid washing, and rinsing with purified water and water for injection. The flask is then inverted on a drying rack to control moisture. Once dry, the flask is removed from the rack, bandaged, sterilized, and returned to production for reuse.

[0004] The drying rack can support upside-down cell bottles, making it easier to dry them. It is an indispensable device. If production is suspended, the drying rack can also be used as a storage rack to place cell bottles.

[0005] The existing bottle drying rack mainly has the following defects:

[0006] 1. Cell bottle drying takes a long time: During production, cell bottle turnover speed is required to meet production needs. The drying process during the turnover of cell bottles is time-consuming, and complete drying generally takes about 2 days. If a dry heat sterilizer is used for heating and drying, the circulating hot air will blow some tiny dust particles into the bottle, affecting cell adhesion and growth during use.

[0007] 2. The bottle drying rack is heavy and not easy to move: The bottle drying rack is made of stainless steel, which is heavy and not easy to move. It is placed far away from the injection water pipeline. It takes time and manpower to move the cell bottles after cleaning.

[0008] 3. The limiting hole is easy to scratch the wall of the cell bottle: The limiting hole is made of stainless steel. When the glass cell bottle is turned upside down, it is easy to be scratched by the edge of the limiting hole, which affects the effect of microscopic observation of cells. At the same time, there is a safety hazard for the operator who puts the cell bottle on the shelf.

[0009] 4. It can easily cause cell bottle collisions: When a cell bottle is turned upside down, slow speed affects work efficiency, while fast speed can easily cause the tails of the cell bottles to collide. Patent CN219546950U discloses "A bracket for placing cell culture bottles and controlling water in them." It has elastic parts installed on the limit plate to prevent two cell culture bottles from colliding when placed adjacent to each other, thus avoiding damage to the culture bottles. In actual applications, elastic parts can indeed reduce collisions between adjacent cell bottles to a certain extent, but 15L cell bottles are tall, heavy, and prone to tilting, so it cannot be guaranteed to completely avoid collisions. Moreover, when the cell bottles are tilted, they tend to collect water, affecting the drying speed of the cell bottles. Summary of the Invention

[0010] The purpose of the utility model is to overcome the deficiencies of the prior art and provide a bottle drying rack for quickly drying cell culture bottles, so as to increase the drying speed, avoid collision and scratching of the bottles and improve space utilization.

[0011] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0012] A bottle drying rack for quickly drying cell culture bottles comprises a frame body, the bottom of which is connected to a caster group, the upper and lower ends of the frame body are respectively provided with bottle drying mechanisms of the same structure, the bottle drying mechanism comprises an upper plate, a lower plate, an air blowing assembly and a water receiving tray which are sequentially arranged from top to bottom, the upper plate is provided with upper limit holes arranged in a matrix, the lower plate is provided with coaxially arranged lower limit holes corresponding to each upper limit hole, the neck of the cell bottle is nested in the lower limit hole, and the bottle body of the cell bottle is nested in the upper limit hole; the air blowing assembly comprises a main air inlet pipe and a branch air inlet pipe, the air inlet end of the main air inlet pipe is connected to a clean compressed air source, one end of the branch air inlet pipe is closed, and the other end of the branch air inlet pipe is connected to the main air inlet pipe through a ball valve, a plurality of air blowing pipes for blowing upwards are connected to the branch air inlet pipe, and each air blowing pipe is respectively arranged corresponding to each lower limit hole.

[0013] Furthermore, the entire frame is formed of stainless steel.

[0014] Furthermore, the caster set includes two fixed casters and two universal casters, both with foot brakes, wherein the two fixed casters are connected to the bottom of the wide surface on one side of the frame, and the two universal casters are connected to the bottom of the wide surface on the other side of the frame.

[0015] Furthermore, corresponding rubber rings are fixed to the edges of the hole walls of the upper limit hole and the lower limit hole respectively.

[0016] Furthermore, the air inlet end of the main air inlet pipe is provided with a quick connector, which is connected to a clean compressed air source through the quick connector.

[0017] The utility model adopts the above technical solution, which has the following beneficial effects:

[0018] 1. Increase the drying speed: Place a layer of air blowing components between the bottom plate and the water tray. Use clean compressed air from the clean area to dry the cell bottles. It will take 15 to 30 minutes to completely dry.

[0019] 2. Improved shelving efficiency: The main body of the bottle drying rack is made of stainless steel and is quite heavy. To facilitate movement, a caster is installed on each of the four support columns at the bottom of the rack. The wide side of the bottle drying rack has two universal casters, which facilitate movement in all directions. The other wide side has two fixed casters, each with a foot brake. After installing the casters, the bottle drying rack can be moved near the sink, making it easier to shelve the cell bottles after washing, thereby improving work efficiency. The bottle drying rack can also function as a cart, moving the cell bottles to their destination for dressing and sterilization.

[0020] 3. Anti-scratch design: The edges of the upper and lower limit holes are embedded with a 2mm thick rubber ring, which can effectively prevent the cell bottle wall from being scratched;

[0021] 4. Anti-collision design: There are two limit holes designed, the lower limit hole supports the neck of the cell bottle, and the upper limit hole ensures that the cell bottle is relatively upright, not easy to collect water, and adjacent cell bottles will not collide. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments:

[0023] Figure 1 It is a three-dimensional diagram of the utility model;

[0024] Figure 2 It is a front view of the utility model;

[0025] Figure 3 It is a side view of the utility model;

[0026] Figure 4 This is an exploded diagram of the air blowing component;

[0027] Figure 5 This is a schematic diagram of the positions of the upper limit hole, lower limit hole and air blow pipe. DETAILED DESCRIPTION

[0028] like Figure 1-5As shown, the present invention includes a frame 1, which is a three-dimensional rectangular frame made of stainless steel. A caster set is connected to the bottom of the frame 1. The caster set includes two fixed casters 2 and two universal casters 3, each with a foot brake. The two fixed casters 2 are connected to the bottom of the wide side of one side of the frame 1, and the two universal casters 3 are connected to the bottom of the wide side of the other side of the frame 1. After the casters are installed on the bottle drying rack, the bottle drying rack can be moved to the vicinity of the sink, making it easier to put the cell bottles on the shelves after washing, thereby improving work efficiency. The bottle drying rack can also serve as a trolley to move the cell bottles to their destination for bandaging and sterilization.

[0029] The upper and lower ends of the frame 1 are each equipped with a bottle drying mechanism 4 of identical structure. This mechanism comprises an upper plate 41, a lower plate 42, an air blowing assembly 43, and a water receiving tray 44, arranged sequentially from top to bottom. The upper plate 41 is provided with upper limit holes 411 arranged in a matrix, while the lower plate 42 is provided with coaxially arranged lower limit holes 421 corresponding to each upper limit hole 411. The neck of the cell bottle nests in the lower limit holes 421, while the body of the cell bottle nests in the upper limit holes 411. Two limit holes are provided: the lower limit holes 421 prevent the bottle from falling, while the upper limit holes 411 prevent the bottle from colliding.

[0030] The air blowing assembly 43 includes a main air inlet pipe 431 and a branch air inlet pipe 432. The air inlet end of the main air inlet pipe 431 is equipped with a quick connector 434, which connects to a clean compressed air source. One end of the branch air inlet pipe 432 is sealed, and the other end is connected to the main air inlet pipe 431 via a ball valve 435. Multiple upward-blowing air pipes 433 are connected to the branch air inlet pipe 432, each corresponding to a lower limit hole 421. The air blowing assembly 43 uses clean compressed air to quickly dry the cell bottles. The air outlet pipe should be slightly lower than the lower limit hole 421 to facilitate storage of the cell bottles.

[0031] As an example, the upper plate 41 is a stainless steel plate with three rows of 240 mm diameter upper limit holes 411 machined into it. A 2 mm thick rubber ring 45 is embedded around the edges of the upper limit holes 411 and secured with glass glue. The number of upper limit holes 411 in each row can be customized. For example, if there are seven upper limit holes 411 per row, 21 cell bottles can be dried on one plate.

[0032] The lower plate 42 is constructed from a stainless steel plate with three rows of 120mm diameter lower limit holes 421 machined into them. A 2mm thick rubber ring is embedded around the edges of these lower limit holes 421 and secured with glass glue. The number of lower limit holes 421 in each row matches the number of upper limit holes 411 in the upper plate 41, and their centers correspond one to one. The diameters of the lower limit holes 421 and upper limit holes 411 are designed to accommodate 5L, 10L, and 15L cell bottles, and the vertical distance between the lower limit holes 421 and upper limit holes 411 is 250-300mm.

[0033] After clean air enters the main air intake pipe 431, it is blown through the blow pipe 433 to dry the bottles. The main air intake pipe 431 branches into three rows of branch air intake pipes 432 on the upper and lower levels, respectively. Each row of branch air intake pipes 432 is equipped with multiple blow pipes 433. The blow pipes 433 are approximately 8 mm in diameter and 80 mm in height, matching the number of lower limit holes 421 and corresponding to their centers. The blow pipes 433 must not be higher than the lower limit hole 421; if they are, the bottle drying rack's ability to store bottles will be affected. Each branch air intake pipe 432 has a separate ball valve 435 to control the air intake.

[0034] To prevent the air blow tube 433 from not being fully loaded with cell bottles and wasting clean air, several additional plugs are required to block the clean air. If there are 7 limit holes in a row, 6 will suffice.

[0035] The water collection tray 44 receives water from the cell bottles and is located below, but not in contact with, the branch air inlet tube 432. The tray 44 consists of three identical stainless steel plates with a barrier approximately 10 mm high. The water in the tray 44 is small and evaporates naturally, eliminating the need for drainage. The tray 44 is designed as a drawer, allowing it to be removed at any time for easy cleaning of the tray 44 and the air blowing assembly 43 above it.

[0036] The above describes the specific implementation of the present invention, but those skilled in the art should understand that this is only an example. Those skilled in the art can make various changes or modifications to this implementation without departing from the principle and essence of the present invention, but these changes and modifications will fall within the scope of protection of the present invention.

Claims

1. A drying rack for rapidly drying cell culture bottles, comprising a frame body, the bottom of which is connected to a caster set, characterized in that: The upper and lower ends of the frame are respectively provided with bottle drying mechanisms of the same structure, which include an upper plate, a lower plate, an air blowing assembly and a water receiving tray which are sequentially arranged from top to bottom. The upper plate is provided with upper limit holes arranged in a matrix, and the lower plate is provided with coaxial lower limit holes corresponding to each upper limit hole. The mouth and neck of the cell bottle are nested in the lower limit holes, and the bottle body of the cell bottle is nested in the upper limit holes; the air blowing assembly includes a main air inlet pipe and a branch air inlet pipe, the air inlet end of the main air inlet pipe is connected to a clean compressed air source, one end of the branch air inlet pipe is closed, and the other end of the branch air inlet pipe is connected to the main air inlet pipe through a ball valve, and a plurality of air blowing pipes for blowing upwards are connected to the branch air inlet pipe, and each air blowing pipe is respectively arranged corresponding to each lower limit hole.

2. The drying rack for rapidly drying cell culture bottles according to claim 1, characterized in that: The frame is entirely formed of stainless steel.

3. The drying rack for rapidly drying cell culture bottles according to claim 1, characterized in that: The caster set includes two fixed casters and two universal casters, both with foot brakes, wherein the two fixed casters are connected to the bottom of the wide surface on one side of the frame, and the two universal casters are connected to the bottom of the wide surface on the other side of the frame.

4. The drying rack for rapidly drying cell culture bottles according to claim 1, characterized in that: Corresponding rubber rings are fixed to the hole wall edges of the upper limit hole and the lower limit hole respectively.

5. The drying rack for rapidly drying cell culture bottles according to claim 1, characterized in that: The air inlet end of the main air inlet pipe is provided with a quick connector, which is connected to a clean compressed air source through the quick connector.

Citation Information

Patent Citations

  • Support for placing cell culture bottle and controlling water of cell culture bottle

    CN219546950U