Full-automatic dry-type fluorescence immunoassay analyzer

Abstract

The utility model provides a full-automatic dry-type fluorescence immunoassay analyzer, which relates to the technical field of fluorescence immunoassay analyzers, and comprises a clamping and positioning mechanism and a feeding and discharging assembly, a fixedly inserted control observation part is arranged above the side of the clamping and positioning mechanism; a feeding and discharging assembly for bolt assembly is arranged above the side of the control observation component and comprises a lifting frame, a cross beam, a hydraulic cylinder, a push rod, a lifting block and a pneumatic clamp. A reagent can be continuously put into a detection position by controlling the observation component and the feeding and discharging component, and the driven gear can drive the assembly plate and the rotating column to rotate through meshing transmission operation of the driving gear and the driven gear, so that the lower empty disc and the upper disc rotate adaptively; therefore, the reagent can be effectively clamped in an increasing manner under the mutual cooperation of the hinged base and the clamping strip, so that the efficiency and quantity of single-time detection are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of fluorescent immunoassay analyzers, in particular to a full-automatic dry-type fluorescent immunoassay analyzer. Background Art

[0002] The fluorescence immunoassay instrument is an in vitro microanalyzer that uses non-radioactive isotope immunoassay technology. Based on the characteristics of the fluorescence spectrum of the fluorescent marker, it delays the measurement time and eliminates the interference of nonspecific fluorescence in the specimen to achieve accurate quantitative analysis. Time-resolved fluorescence immunoassays are commonly used for the determination of proteins and polypeptide hormones, haptens, pathogen antigens and antibodies, tumor marker analysis, dried blood spot samples, nucleic acids, and natural killer cell activity.

[0003] When using an existing fluorescent immunoassay analyzer, such as application number CN202220121855.X, which relates to the field of analyzers, a fully automatic dry fluorescent immunoassay analyzer is disclosed, including a reaction tank, a base is fixedly connected to the middle of the inner bottom end of the reaction tank, the inner upper end of the base is fixedly connected to a laser emitting device, and vertical plates are fixedly connected to the left and right sides of the top of the base, and the bottom ends of the vertical plates are respectively fixedly connected to support frames. In the present utility model, by moving the sliding rods toward the two ends of the outer side of the laser emitting device and fixing the position of the sliding rods by locating pins, the bottom end of the arc-shaped plate can be brought closer to the middle of the laser emitting device, and the splint can thereby support the plate for fixed support; however, in the above-mentioned technology, only one group of reagents can be detected at a time, which is not convenient for improving the efficiency of detection. Therefore, the present utility model proposes a fully automatic dry fluorescent immunoassay analyzer to solve the problems existing in the prior art. Utility Model Content

[0004] In response to the above problems, the present invention proposes a fully automatic dry fluorescent immunoassay analyzer, which mainly utilizes the control observation component and the feed and discharge components to continuously place the reagents into the detection position. Through the meshing transmission operation of the driving gear and the driven gear, the driven gear can drive the rotation of the assembly plate and the rotating column to allow the lower empty plate and the upper plate to rotate adaptively. In this way, the mutual cooperation of the articulated base and the clamping bar can effectively clamp the reagents in increments, thereby improving the efficiency of a single test.

[0005] To achieve the purpose of the utility model, the utility model is implemented through the following technical solutions: a fully automatic dry fluorescent immunoassay analyzer, including a clamping and positioning mechanism and an inlet and outlet assembly, a fixed plug-in control and observation component is provided above the side of the clamping and positioning mechanism, and a bolt-assembled inlet and outlet assembly is provided above the side of the control and observation component;

[0006] The material inlet and outlet components include a lifting frame, a crossbeam, a hydraulic cylinder, a push rod, a lifting block and a pneumatic clamp. The lifting frame is bolted to the upper side of the control and observation component. A crossbeam is provided on the top side of the lifting frame, and a push rod connected to the output end of the hydraulic cylinder is provided on the inner bottom side of the crossbeam. A lifting block is provided below the push rod, and a pneumatic clamp is provided below the lifting block.

[0007] As a preferred embodiment of the present invention, the central axis of the lifting block and the central axis of the pneumatic clamp are on the same straight line, and the hydraulic cylinder and the push rod are symmetrically distributed about the central axis of the beam.

[0008] As a preferred embodiment of the present invention, the clamping and positioning mechanism includes a base block, a base plate, a plug-in base, a sleeve seat, a driving gear, a driven gear, an assembly plate, a rotating column, a lower empty plate, an elastic card, a lens, a laser lamp, an upper plate, a hinged base and a clamping bar. The top side of the base block is provided with a base plate, and the top side of the base plate is provided with a plug-in base, the top side of the plug-in base is provided with a sleeve seat, and the inner bottom end of the sleeve seat is provided with a driving gear and a driven gear.

[0009] As a preferred embodiment of the present invention, the output end of the driven gear is provided with an assembly plate passing through the shaft sleeve seat, a rotating column is provided above the assembly plate, and a lower empty plate is provided on the inner bottom side of the rotating column, an elastic card is provided on the inner side of the inner groove of the lower empty plate, a lens is provided below the inner groove of the lower empty plate, and a laser light is provided below the side of the lower empty plate.

[0010] As a preferred embodiment of the present invention, the top end of the rotating column is provided with an upper plate assembled with bolts, and the outer end of the upper plate is provided with a hinged base, and one end of the hinged base is provided with a clamping strip.

[0011] As a preferred embodiment of the present invention, the control and observation component includes a glass cabinet, a top cover, a pneumatic card cover, a top disk, a detection head and a control panel. The glass cabinet is arranged above the four sides of the base plate. A top cover for installing the pneumatic card cover is provided on the top of the glass cabinet. The inner bottom side of the top cover is connected to the detection head through the top disk bolts, and a control panel is provided above one end of the top cover.

[0012] The beneficial effects of the utility model are:

[0013] The utility model mainly utilizes the control observation component and the material inlet and outlet components to continuously place the reagents into the detection position. Through the meshing transmission operation of the driving gear and the driven gear, the driven gear can drive the rotation of the assembly plate and the rotating column to allow the lower empty plate and the upper plate to rotate adaptively. In this way, the mutual cooperation of the articulated base and the clamping bar can effectively clamp the reagents in increasing numbers, thereby improving the efficiency of a single test. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0015] Figure 2 This is a bottom-up three-dimensional structural diagram of the present invention;

[0016] Figure 3 This is a schematic diagram of the three-dimensional structure of the clamping and positioning mechanism of the present utility model;

[0017] Figure 4 This is a schematic diagram of the three-dimensional structure of the driving gear and the driven gear of the utility model;

[0018] Figure 5 This is a schematic diagram of the three-dimensional structure of the elastic card and laser light of the utility model.

[0019] 1. Clamping and positioning mechanism; 101. Base block; 102. Base plate; 103. Plug-in base; 104. Bushing seat; 105. Driving gear; 106. Driven gear; 107. Assembly plate; 108. Rotating column; 109. Lower empty plate; 1010. Elastic card; 1011. Lens; 1012. Laser light; 1013. Upper plate; 1014. Articulated base; 1015. Clamping bar; 2. Control and observation components; 201. Glass cabinet; 202. Top cover; 203. Pneumatic card cover; 204. Top plate; 205. Detection head; 206. Control panel; 3. Feeding and discharging components; 301. Lifting frame; 302. Crossbeam; 303. Hydraulic cylinder; 304. Push rod; 305. Lifting block; 306. Pneumatic clamp. DETAILED DESCRIPTION

[0020] In order to deepen the understanding of the present invention, the present invention will be further described in detail below in conjunction with embodiments. The embodiments are only used to explain the present invention and do not constitute a limitation on the scope of protection of the present invention.

[0021] according to Figure 1-5 As shown, this embodiment proposes a fully automatic dry fluorescent immunoassay analyzer, including a clamping and positioning mechanism 1 and an inlet and outlet assembly 3. A fixed and plugged control and observation component 2 is provided above the side of the clamping and positioning mechanism 1, and a bolt-assembled inlet and outlet assembly 3 is provided above the side of the control and observation component 2;

[0022] The material inlet and outlet assembly 3 includes a lifting frame 301, a beam 302, a hydraulic cylinder 303, a push rod 304, a lifting block 305 and a pneumatic clamp 306. The lifting frame 301 is bolted to the upper side of the control and observation component 2. The top side of the lifting frame 301 is provided with a beam 302, and the inner bottom side of the beam 302 is provided with a push rod 304 connected to the output end of the hydraulic cylinder 303. A lifting block 305 is provided below the push rod 304, and a pneumatic clamp 306 is provided below the lifting block 305.

[0023] The central axis of the lifting block 305 and the central axis of the pneumatic clamp 306 are on the same straight line, and the hydraulic cylinder 303 and the push rod 304 are symmetrically distributed about the central axis of the beam 302.

[0024] In this embodiment, the pneumatic clamp 306 is then used to clamp the reagent, and then the hydraulic cylinder 303 on the top side of the beam 302 is used to output power to drive the output end to operate. When the hydraulic cylinder 303 outputs power, it can drive the hydraulic cylinder 303 outputs power to drive the push rod 304 to place the reagent clamped by the lifting block 305 and the pneumatic clamp 306 into the glass cabinet 201.

[0025] The clamping and positioning mechanism 1 includes a base block 101, a base plate 102, a plug-in base 103, a sleeve seat 104, a driving gear 105, a driven gear 106, an assembly plate 107, a rotating column 108, a lower empty plate 109, an elastic card 1010, a lens 1011, a laser lamp 1012, an upper plate 1013, a hinged base 1014 and a clamping bar 1015. The base plate 102 is provided on the top side of the base block 101, and the plug-in base 103 is provided on the top side of the base plate 102. The sleeve seat 104 is provided on the top side of the plug-in base 103, and the driving gear 105 and the driven gear 106 are provided at the inner bottom end of the sleeve seat 104.

[0026] In this embodiment, after the reagent is clamped, the driving gear 105 on the sleeve seat 104 is used to output power to drive the output end to operate, so that the driven gear 106 is engaged and transmitted, and the rotating column 108 on the assembly plate 107 can be used to change the position of the reagent to facilitate the placement of multiple groups of reagents.

[0027] The output end of the driven gear 106 passes through the shaft sleeve seat 104 and is provided with an assembly plate 107. A rotating column 108 is provided above the assembly plate 107, and a lower empty plate 109 is provided on the inner bottom side of the rotating column 108. An elastic card 1010 is provided on the inner side of the inner groove of the lower empty plate 109, a lens 1011 is provided below the inner groove of the lower empty plate 109, and a laser lamp 1012 is provided below the side of the lower empty plate 109.

[0028] In this embodiment, when the reagent is placed on the lower empty tray 109, the elastic card 1010 limits the reagent, and the lens 1011 and the laser lamp 1012 output laser light to effectively perform detection.

[0029] The top of the rotating column 108 is provided with an upper plate 1013 assembled with bolts, and the outer end of the upper plate 1013 is provided with a hinge base 1014, and one end of the hinge base 1014 is provided with a clamping bar 1015.

[0030] In this embodiment, after the reagent is supported in a limited position, the hinged base 1014 on the upper plate 1013 is used to output power to drive the output end to extend and retract, so that the hinged base 1014 and the clamping bar 1015 cooperate with each other to effectively clamp and fix the reagent.

[0031] The control and observation component 2 includes a glass cabinet 201, a top cover 202, a pneumatic card cover 203, a top disk 204, a detection head 205 and a control panel 206. The glass cabinet 201 is arranged above the four sides of the base plate 102. The top of the glass cabinet 201 is provided with a top cover 202 for installing the pneumatic card cover 203. The inner bottom side of the top cover 202 is bolted to the detection head 205 through the top disk 204. A control panel 206 is provided above one end of the top cover 202.

[0032] In this embodiment, when in use, the control panel 206 above one end of the top cover 202 is operated to output the instruction. After the instruction is output, the pneumatic card cover 203 is opened and the detection head 205 below the top disk 204 is started to observe the clamping and positioning mechanism 1 in real time.

[0033] The working principle of the fully automatic dry fluorescent immunoassay analyzer is as follows: when in use, the control panel 206 above one end of the top cover 202 is operated to output the command, and after the command is output, the pneumatic card cover 203 is opened, and the detection head 205 below the top disk 204 is started to observe the clamping and positioning mechanism 1 in real time. After the reagent is clamped, the driving gear 105 on the shaft sleeve seat 104 is used to output power to drive the output end to operate so that the driven gear 106 is engaged and the rotating column 108 on the assembly plate 107 can be used to change the position of the reagent, so as to facilitate the placement of multiple groups of reagents. When the reagent is placed on the lower empty disk 109, the spring is pressed. The sex card 1010 limits the reagent, and it can be effectively detected after the lens 1011 and the laser lamp 1012 output the laser. After the reagent is limited and supported, the hinged base 1014 on the upper plate 1013 is used to output power to drive the output end to extend and retract, so that the hinged base 1014 and the clamping bar 1015 cooperate with each other to effectively clamp and fix the reagent. After the reagent is clamped, the active gear 105 on the sleeve seat 104 is used to output power to drive the output end to operate, so that the driven gear 106 is engaged and transmitted, and the rotating column 108 on the assembly plate 107 can be used to change the position of the reagent, so as to facilitate the placement of multiple groups of reagents.

[0034] The above shows and describes the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and improvements may be made to the present invention without departing from the spirit and scope of the present invention. Such changes and improvements are intended to fall within the scope of the present invention. The scope of protection claimed in this invention is defined by the appended claims and their equivalents.

Claims

1. A fully automatic dry-type fluorescent immunoassay analyzer, comprising a clamping and positioning mechanism (1) and an inlet and outlet assembly (3), characterized in that: A fixed and plugged control and observation component (2) is provided above the side of the clamping and positioning mechanism (1), and a bolt-assembled feeding and discharging assembly (3) is provided above the side of the control and observation component (2); The feeding and discharging assembly (3) includes a lifting frame (301), a crossbeam (302), a hydraulic cylinder (303), a push rod (304), a lifting block (305) and a pneumatic clamp (306). The lifting frame (301) is bolted to the upper side of the control and observation component (2). The top side of the lifting frame (301) is provided with a crossbeam (302), and the inner bottom side of the crossbeam (302) is provided with a push rod (304) connected to the output end of the hydraulic cylinder (303). A lifting block (305) is provided below the push rod (304), and a pneumatic clamp (306) is provided below the lifting block (305).

2. A fully automatic dry-type fluorescent immunoassay analyzer according to claim 1, characterized in that: The central axis of the lifting block (305) and the central axis of the pneumatic clamp (306) are on the same straight line, and the hydraulic cylinder (303) and the push rod (304) are symmetrically distributed around the central axis of the crossbeam (302).

3. The fully automatic dry-type fluorescent immunoassay analyzer according to claim 1, characterized in that: The clamping and positioning mechanism (1) comprises a base block (101), a base plate (102), a plug-in base (103), a shaft sleeve seat (104), a driving gear (105), a driven gear (106), an assembly plate (107), a rotating column (108), a lower empty plate (109), an elastic card (1010), a lens (1011), a laser light (1012), an upper plate (1013), a hinged base (1014) and a clamping bar (1015); the top side of the base block (101) is provided with a base plate (102), the top side of the base plate (102) is provided with a plug-in base (103), the top side of the plug-in base (103) is provided with a shaft sleeve seat (104), and the inner bottom end of the shaft sleeve seat (104) is provided with a driving gear (105) and a driven gear (106).

4. A fully automatic dry-type fluorescent immunoassay analyzer according to claim 3, characterized in that: The output end of the driven gear (106) passes through the shaft sleeve seat (104) and is provided with an assembly plate (107); a rotating column (108) is provided above the assembly plate (107); and a lower empty disk (109) is provided on the inner bottom side of the rotating column (108); an elastic card (1010) is provided on the inner side of the inner groove of the lower empty disk (109); a lens (1011) is provided below the inner groove of the lower empty disk (109); and a laser lamp (1012) is provided below the side of the lower empty disk (109).

5. The fully automatic dry-type fluorescent immunoassay analyzer according to claim 3, characterized in that: The top end of the rotating column (108) is provided with an upper plate (1013) assembled with bolts, and the outer end of the upper plate (1013) is provided with a hinged base (1014), and one end of the hinged base (1014) is provided with a clamping bar (1015).

6. The fully automatic dry-type fluorescent immunoassay analyzer according to claim 3, characterized in that: The control and observation component (2) comprises a glass cabinet (201), a top cover (202), a pneumatic card cover (203), a top plate (204), a detection head (205) and a control panel (206); the glass cabinet (201) is arranged above the four sides of the base plate (102); a top cover (202) for mounting the pneumatic card cover (203) is arranged at the top of the glass cabinet (201); the inner bottom side of the top cover (202) is bolted to the detection head (205) via the top plate (204); and a control panel (206) is arranged above one end of the top cover (202).

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