Serum and plasma sample separation device

Abstract

The utility model discloses a serum and plasma sample separating device, which comprises a box body, a conveying belt, a sample frame, an ultrasonic detector and a mechanical arm, the box body is provided with a feed port and a discharge port, the conveying belt penetrates through the feed port and the discharge port, the sample frame is placed on the conveying belt and is used for conveying the sample frame, and the ultrasonic detector is arranged on the conveying belt. The ultrasonic detector is fixedly arranged on the box body and located above the conveying belt, the mechanical arm is arranged in the box body, and a sampling mechanism is arranged at the tail end of the mechanical arm; according to the utility model, a sample tube containing serum and plasma is placed on the sample frame, the sample frame enters the box body through the conveying of the conveying belt, the ultrasonic detector can detect the sample tube to obtain the height of two components in the sample tube, and then the mechanical arm drives the sampling mechanism to be inserted into the sample tube to suck one component; the two components are separated, so that the separation is more accurate, and the deviation of a detection result caused by sample pollution is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of blood separation, in particular to a serum and plasma sample separation device. Background Art

[0002] In the field of blood sample testing, in order to meet the testing needs of some customers, blood samples in the laboratory need to be stored for a long time so that they can be sampled and tested at any time. However, the blood components in whole blood samples are relatively complex. Long-term storage will cause some test substances to naturally degrade and red blood cells to be destroyed, resulting in inaccurate test results. Therefore, it is necessary to extract blood samples and separate serum and plasma to achieve the purpose of long-term storage.

[0003] Currently, serum and plasma are generally separated by centrifuge to separate them into layers. Then, samples are taken manually and a pipette is inserted into the sample tube to separate the serum and plasma and store them separately. However, traditional manual extraction is labor-intensive. Moreover, although layers will be formed after serum and plasma separation, the serum and plasma are still in the same test tube. If the pipette insertion depth is not accurate, the separation of the two components in the sample tube will not be thorough enough, causing sample contamination and affecting subsequent test results. Utility Model Content

[0004] The purpose of the present invention is to provide a serum plasma sample separation device to address the deficiencies of the above-mentioned prior art.

[0005] In order to solve the above problems, the technical solution adopted by the present invention is:

[0006] A serum-plasma sample separation device comprises a box body, wherein the box body is provided with a feed inlet and a discharge outlet;

[0007] A conveyor belt is provided on the box body, and the conveyor belt passes through the feed port and the discharge port;

[0008] The sample rack is placed on the conveyor belt;

[0009] The ultrasonic detector is fixedly installed in the box and located above the conveyor belt;

[0010] The mechanical arm is arranged in the box body, and the sampling mechanism is provided on the mechanical arm.

[0011] Preferably, the sampling mechanism includes a shell, the shell is connected to the end of the robotic arm, a pipette is provided at the bottom of the shell, a liquid suction component is provided in the shell, and a pushing component is also provided in the shell.

[0012] Preferably, the pipette assembly includes a pipette connected to a pipette, a piston is slidably provided in the pipette, a power piece is provided on the top of the pipette, and the power piece is connected to the piston for driving the piston to slide in the pipette.

[0013] Preferably, the ejection assembly includes an ejection cylinder, which is fixedly arranged in the outer shell. A ejection rod is fixedly connected to the piston rod of the ejection cylinder. A push plate is provided at one end of the ejection rod away from the ejection cylinder, and the push plate is slidably arranged on the outer wall of the pipette.

[0014] Preferably, a gun tip rack and a waste rack are fixedly provided in the box body, and the gun tip rack and the waste rack are respectively located on both sides of the robotic arm.

[0015] Preferably, the box body is provided with an upper cover, and the upper cover is rotatably connected to the box body.

[0016] Preferably, a barcode scanner is also provided in the box.

[0017] Preferably, the sample rack comprises a top plate, a bottom plate and two side plates, and the top plate is provided with two rows of sample holes.

[0018] The beneficial effects of adopting the above technical solution are:

[0019] In the present invention, a sample tube containing layered serum and plasma is placed on a sample rack, which is transported into a box by a conveyor belt. An ultrasonic detector detects the sample tube and can obtain different feedback according to the different components of serum and plasma, and obtain the heights of the two components. The robotic arm can insert a pipette into the sample to absorb one of the substances, thereby separating them more accurately. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a three-dimensional schematic diagram of the utility model;

[0021] Figure 2 This is a three-dimensional schematic diagram of the present invention from another angle;

[0022] Figure 3 It is a schematic diagram of the internal structure of the utility model;

[0023] Figure 4 This is a schematic diagram of the sampling mechanism structure of the utility model;

[0024] Figure 5 It is a three-dimensional schematic diagram of the sample rack of the present utility model.

[0025] In the figure: 1 is the box, 2 is the feed port, 3 is the discharge port, 4 is the conveyor belt, 5 is the sample rack, 6 is the ultrasonic detector, 7 is the robotic arm, 8 is the housing, 9 is the pipette, 10 is the pipette, 11 is the power element, 12 is the ejection cylinder, 13 is the ejection rod, 14 is the push plate, 15 is the tip rack, 16 is the waste rack. 17 is the upper cover, 18 is the barcode scanner, 19 is the top plate, 20 is the bottom plate, 21 is the side plate, and 22 is the sample well. DETAILED DESCRIPTION

[0026] The following embodiments of the present invention are described in further detail with reference to the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0027] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating positions or relationships, are based on the positions or relationships shown in the accompanying drawings and are intended solely to facilitate the description of this utility model and simplify the description. They do not indicate or imply that the devices or components referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0028] In the description of this utility model, it should be noted that, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; mechanical connections, electrical connections; direct connections, indirect connections through an intermediate medium, and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on the specific circumstances.

[0029] like Figures 1 to 3As shown, a serum plasma sample separation device includes a box body 1, a conveyor belt 4, a sample rack 5, an ultrasonic detector 6 and a robotic arm 7. The box body 1 is a box-shaped structure with an upper end opening. The upper end of the box body 1 is rotatably connected to a top cover 17 for sealing the box body 1. When the top cover 17 is opened, it is also convenient for repairing the equipment inside the box body 1 and taking and placing the items inside. The left and right sides of the box body 1 are respectively provided with a feed port 2 and a discharge port 3. The conveyor belt 4 passes through the feed port 2 and the discharge port 3. The sample rack 5 is placed on the conveyor belt 4. The sample rack 5 includes a top plate 19, a bottom plate 20 and two side plates 21. The top plate 19 is provided with two rows of sample holes 22, one row of sample holes 22 is used to place sample tubes after serum and plasma are separated, and the other row of sample holes 22 is used to place empty sample tubes. The ultrasonic detector 6 is located in the box body 1 and is fixedly connected to the upper cover 17. The ultrasonic detector 6 is located above the conveyor belt 4. The robotic arm 7 is disposed in the box body 1 and is provided with a sampling mechanism. In the present invention, the sample tubes containing stratified serum and plasma and the empty sample tubes are respectively placed in the two rows of sample holes 22, and the sample rack 5 is placed on the conveyor belt 4. The conveyor belt 4 is transported forward to transport the sample rack 5 from the feed port 2 to the box body 1. When the sample rack 5 passes under the ultrasonic detector 6, the ultrasonic detector 6 can obtain the depth of the serum and plasma based on the signal feedback obtained according to the different components of the serum and plasma. Then, the robotic arm 7 can insert the sampling mechanism into the sample tube according to the depth obtained by the ultrasonic detector 6, absorb the components located on the upper layer of the sample tube, and then transfer the absorbed components to the empty sample tube. Finally, the conveyor belt 4 can transport the separated sample out from the discharge port 3. The use of ultrasonic detection and robotic arm sampling can make sample collection more accurate and make subsequent test results more accurate; at the same time, it saves manpower and reduces labor intensity.

[0030] like Figure 4As shown, further, the sampling mechanism includes a shell 8, the shell 8 is connected to the end of the robotic arm 7, a pipette 9 is provided at the bottom of the shell 8, a liquid suction component is provided in the shell 8, the liquid suction component includes a pipette 10, the pipette 10 is fixedly provided in the shell 8, the pipette 10 is connected to the pipette 9, a piston is slidably provided in the pipette 10, a power piece 11 is provided on the top of the pipette 10, the power piece 11 is connected to the piston, and is used to drive the piston to suck liquid. The liquid pipe 10 slides. In this embodiment, the power member 11 can be an electric push rod. The piston rod of the electric push rod is fixedly connected to the piston in the pipette 10. The shell 8 is also provided with an ejection component, and the ejection component includes an ejection cylinder 12. The ejection cylinder 12 is fixedly arranged in the shell 8. The piston rod of the ejection cylinder 12 is fixedly connected with an ejection rod 13. The ejection rod 13 is provided with a push plate 14 at one end away from the ejection cylinder 12. The push plate 14 is slidably arranged on the outer wall of the pipette 9. In this embodiment, since a sampling tube needs to be inserted into the pipette 9 during the sampling process, and a new sampling tube needs to be inserted each time sampling is performed to avoid contamination of the sample, the sampling tube is first inserted into the pipette 9 before sampling, and then the robotic arm 7 drives the sampling tube to be inserted into the sample tube containing the sample. At this time, the power part 11 drives the piston in the pipette 10 to move, and the sample can be sucked into the sampling tube. After the sampling is completed, the robotic arm 7 drives the sampling tube containing the sample to be inserted into the empty sample tube, and the power part 11 drives the piston to move in the opposite direction, and the sample in the sampling tube can be sent into the empty sample tube. After the sample separation is completed, the piston rod of the pushing cylinder 11 is extended, driving the pushing rod 13 and the push plate 14 to move downward, and the push plate 14 can push the sampling tube inserted into the pipette 9.

[0031] Furthermore, a gun tip rack 15 and a discard rack 16 are fixedly provided in the box body 1, and the gun tip rack 15 and the discard rack 16 are respectively located on both sides of the robotic arm 7. A new sampling tube is placed on the gun tip rack 15. Before sampling, the robotic arm 7 first inserts a new sampling tube from the gun tip rack 15 into the pipette 9, and the sampling tube after sampling is placed on the discard rack 16. After sampling is completed, the robotic arm 7 moves to the discard rack 16, and the pushing component can push the sampling tube on the pipette 9 out and drop it on the discard rack 16.

[0032] Furthermore, a barcode scanner 18 is also provided in the box body 1. Since the sample rack 5 is formed by a combination of a top plate 19, a bottom plate 20 and a side plate 21, the front and rear sides of the sample rack 5 are not blocked. The sampling tube on the sample rack 5 can be pasted with QR code information to record the information of the sampling tube. The barcode scanner 18 can scan the QR code information and record the information to avoid errors later.

[0033] In another embodiment, if Figure 5As shown, there are two sample racks 5, each of which is provided with a row of sample holes 22. Magnets are provided on one side of the two sample racks 5. When the two sample racks 5 are put together, two rows of sample holes 22 can be formed for inserting sample tubes containing samples and new sample tubes. The magnets attract each other to make the combination of the two sample racks 5 more secure.

[0034] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A serum plasma sample separation device, characterized in that: It comprises a box body (1), wherein the box body (1) is provided with a feed port (2) and a discharge port (3); A conveyor belt (4) is provided on the box body (1), and the conveyor belt (4) passes through the feed port (2) and the discharge port (3); The sample rack (5) is placed on the conveyor belt (4); An ultrasonic detector (6) is fixedly arranged in the box (1) and located above the conveyor belt (4); A mechanical arm (7) is arranged in the box (1), and a sampling mechanism is provided on the mechanical arm (7).

2. A serum-plasma sample separation device according to claim 1, characterized in that: The sampling mechanism comprises a housing (8), the housing (8) is connected to the end of the mechanical arm (7), a pipette (9) is provided at the bottom of the housing (8), a liquid suction component is provided in the housing (8), and a pushing component is also provided in the housing (8).

3. A serum-plasma sample separation device according to claim 2, characterized in that: The liquid pipetting assembly comprises a liquid pipette (10), the liquid pipette (10) is connected to a pipette (9), a piston is slidably provided in the liquid pipette (10), a power piece (11) is provided at the top of the liquid pipette (10), and the power piece (11) is connected to the piston and is used to drive the piston to slide in the liquid pipette (10).

4. The serum-plasma sample separation device according to claim 2, characterized in that: The ejection assembly comprises an ejection cylinder (12), the ejection cylinder (12) is fixedly arranged in the housing (8), the piston rod of the ejection cylinder (12) is fixedly connected to an ejection rod (13), and the end of the ejection rod (13) away from the ejection cylinder (12) is provided with a push plate (14), and the push plate (14) is slidably arranged on the outer wall of the pipette (9).

5. The serum-plasma sample separation device according to claim 1, characterized in that: A gun tip rack (15) and a discard rack (16) are fixedly arranged in the box body (1), and the gun tip rack (15) and the discard rack (16) are respectively located on both sides of the mechanical arm (7).

6. The serum-plasma sample separation device according to claim 1, characterized in that: The box body (1) is provided with an upper cover (17), and the upper cover (17) is rotatably connected to the box body (1).

7. The serum-plasma sample separation device according to claim 1, characterized in that: A code scanner (18) is also provided in the box (1).

8. The serum-plasma sample separation device according to claim 1, characterized in that: The sample rack (5) comprises a top plate (19), a bottom plate (20) and two side plates (21), and two rows of sample holes (22) are provided on the top plate (19).

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