Disposable reaction bag capable of achieving axial movement steering mixing

Abstract

The utility model relates to the technical field of reaction bag mixing, and discloses an axial motion steering mixing disposable reaction bag which comprises a bag body and a mixing device arranged at the bottom of the bag body, the mixing device comprises a mixing disc, an inner connecting rod, an outer connecting rod, a motor and a flexible funnel, the mixing disc is arranged in the bag body, and the flexible funnel is arranged at the bottom of the bag body. One end of the inner and outer connecting rod is connected with the mixing disc, and the other end penetrates through the flexible funnel and is connected with the motor. The mixing disc is arranged in the bag body, the motor controls the inner and outer connecting rods to move axially, the mixing disc is controlled to move in the bag body, liquid medicine in the bag body is mixed, and the device is convenient to operate and good in mixing effect. The mixing disc is connected with the inner-outer connecting rod, the mixing disc is conveniently controlled by the inner-outer connecting rod to move and stir liquid medicine in the bag body, the water passing holes are formed in the mixing disc, the liquid medicine in the water passing holes flows smoothly, the mixing efficiency is higher, and mixing is more thorough. The flexible funnel is arranged to connect the bag body with the inner and outer connecting rods, and up-and-down compressed deformation wrinkles of the flexible funnel can be contained.

Description

Technical Field

[0001] The utility model relates to the field of reaction bag mixing, in particular to a disposable reaction bag capable of axial movement and diversion mixing. Background Art

[0002] A disposable reaction bag is a disposable consumable that provides space for reactants such as cells and microorganisms, as well as the culture fluid they need. During the reaction process, it is often necessary to add culture fluid and other substances, and at this time the contents need to be mixed. At the same time, in order to homogenize the culture process, the reactants also need to be mixed. Whether it is mixing or blending, the contents in the bag need to flow. But it is worth noting that the environment provided by the disposable reaction bag needs to be sterile and airtight. In the prior art, common methods include rocking and paddle types. The rocking type is to place the disposable reaction bag on a shaker, and through the shaking of the shaker, the contents have wave-like fluctuations to achieve the effect of mixing. The paddle type commonly used is a magnetically coupled paddle, which is achieved by arranging magnets circumferentially around the paddle and driving the paddle to rotate with an electromagnetic drive magnet across the bag body.

[0003] Patent application publication number CN 207126459U discloses a mixing system comprising a tank assembly; a container positioned within the tank assembly; a mixer disposed within a compartment of the container; a linear motor having a stroke length; a shaft having a first end fastened to the mixer and an opposite second end fastened to the linear motor; and a measuring device arranged and positioned to measure a thickness of sediment located within the compartment of the container; the measuring device providing a measurement value to the linear motor; and the stroke length of the linear motor being configured to change length in response to the measurement value from the measuring device.

[0004] The flap of the prior art bends downward during its ascent, and has no effect of fanning the liquid for mixing, resulting in low mixing efficiency. The flap is prone to folding when it falls, and the area used for fanning is smaller than the designed area, affecting the mixing effect.

[0005] Therefore, a new technical solution is needed to solve the above technical problems. Utility Model Content

[0006] The utility model aims to provide a disposable reaction bag with axial movement and diversion mixing. When the device is used, the drug liquid is mixed by the displacement of the mixing disk, and the mixing effect is good, the operation is convenient, and the practicability is strong.

[0007] The technical solution adopted in this utility model is:

[0008] A disposable reaction bag with axial motion steering mixing includes a bag body and a mixing device arranged at the bottom of the bag body. The mixing device includes a mixing disk, inner and outer connecting rods, a motor, and a flexible funnel. The mixing disk is arranged inside the bag body, and the flexible funnel is arranged at the bottom of the bag body. One end of the inner and outer connecting rods is connected to the mixing disk, and the other end of the inner and outer connecting rods passes through the flexible funnel. The end of the other end of the inner and outer connecting rods is connected to the motor.

[0009] By adopting the above structure, the motor controls the axial movement of the inner and outer connecting rods, controls the displacement of the mixing disk in the bag body, and performs a mixing operation on the liquid medicine in the bag body. The device is easy to operate and has a good mixing effect.

[0010] Preferably, the mixing disc is integrally injection-molded with the inner and outer connecting rods and is connected to one end of the inner and outer connecting rods. The overall shape is T-shaped, and a plurality of water holes are provided on the mixing disc.

[0011] By adopting the above structure, the mixing disk is connected with the inner and outer connecting rods, which makes it easy to control the mixing disk to move the liquid in the mixing bag through the inner and outer connecting rods. In addition, the mixing disk is provided with water holes, which makes the mixing more thorough and the mixing effect better.

[0012] Preferably, the water hole includes an upper reaming hole, a middle oblique hole, and a lower reaming hole. The apertures of the upper reaming hole and the lower reaming hole are larger than the aperture of the middle oblique hole. The extension direction of the edge of the middle oblique hole intersects with the upper reaming hole and the lower reaming hole. The middle oblique hole is an oblique hole.

[0013] By adopting the above structure, the medicine liquid flows through the water hole more smoothly and the mixing efficiency is higher.

[0014] Preferably, the flexible funnel is a flexible part in the shape of a funnel, the weld edge at the top is connected to the bottom opening of the bag body, and is welded to the inner wall of the bag body. The flexible funnel has an opening at the lower end, and multiple annular sealing protrusions are provided on the inner side of the end.

[0015] By adopting the above structure, the flexible funnel connects the bag body and the inner and outer connecting rods to present a funnel shape. When the inner and outer connecting rods reciprocate up and down, the flexible funnel can accommodate the deformation wrinkles compressed up and down.

[0016] Preferably, the bottom end of the flexible funnel is sleeved on the inner and outer connecting rods, and the flexible funnel is fixed to the inner and outer connecting rods by a clamp.

[0017] Preferably, a plurality of sealing connection recesses are provided at the connection between the bottom ends of the inner and outer connecting rods and the flexible funnel, and the sealing connection recesses are matched with the sealing protrusions.

[0018] By adopting the above structure, the bottom end of the flexible funnel is fixed to the inner and outer connecting rods by a clamp, and matching sealing connection recesses and sealing protrusions are provided at the connection points, so that the sealing performance of the device is better.

[0019] Preferably, a bolt groove is provided at the bottom end of the inner and outer connecting rods, and the bolt groove is connected to the end of the motor connecting rod provided on the motor.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] 1. The utility model sets a mixing disk in the bag body, controls the axial movement of the inner and outer connecting rods by a motor, controls the displacement of the mixing disk in the bag body, and performs a mixing operation on the liquid medicine in the bag body. The device is easy to operate and has a good mixing effect.

[0022] 2. The mixing disk of the device of the utility model is connected with the inner and outer connecting rods, which makes it easy to control the mixing disk to move the liquid medicine in the stirring bag through the inner and outer connecting rods. In addition, the mixing disk is provided with water holes, through which the liquid medicine flows smoothly, the mixing efficiency is higher, and the mixing is more thorough.

[0023] 3. The device of the utility model is provided with a flexible funnel connecting the bag body and the inner and outer connecting rods, which is funnel-shaped. When the inner and outer connecting rods reciprocate up and down, the flexible funnel can accommodate the deformation wrinkles compressed up and down.

[0024] 4. The device of the utility model stirs in an axial motion manner, which can improve the mixing efficiency of cell culture while reducing the shearing of the liquid medicine and reducing the shearing of cells during the mixing process. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a structural diagram of the utility model;

[0026] Figure 2 This is a schematic structural diagram of the mixing disk of the present utility model;

[0027] Figure 3 This is a schematic diagram of the structure of the water hole of the utility model;

[0028] Figure 4 This is an explosion diagram of the utility model.

[0029] Among them: 1. Bag body; 2. Mixing plate; 3. Water hole; 4. Flexible funnel; 5. Clamp; 6. Motor connecting rod; 7. Motor; 8. Upper reaming hole; 9. Middle inclined hole; 10. Lower reaming hole; 11. Inner and outer connecting rods; 12. Sealing protrusion; 13. Welding edge; 14. Bolt groove; 15. Sealing connection depression. DETAILED DESCRIPTION

[0030] like Figure 1-4As shown, a disposable reaction bag with axial motion-directed mixing includes a bag body 1 and a mixing device provided at the bottom of the bag body 1. The mixing device includes a mixing disc 2, an inner and outer connecting rod 11, a motor 7, and a flexible funnel 4. The mixing disc 2 is provided inside the bag body 1, and the flexible funnel 4 is provided at the bottom of the bag body 1. One end of the inner and outer connecting rod 11 is connected to the mixing disc 2, and the other end passes through the flexible funnel 4, and the end is connected to the motor 7. The device sets the mixing disc 2 in the bag body 1, and controls the axial movement of the inner and outer connecting rod 11 by the motor 7, controls the displacement of the mixing disc 2 in the bag body 1, and performs a mixing operation on the liquid medicine in the bag body 1. The device is easy to operate and has a good mixing effect. The device stirs in an axial motion manner, which can reduce the shearing of the liquid medicine while improving the mixing efficiency of cell culture, and reduce the shearing of cells during the mixing process.

[0031] The mixing disc 2 is integrally injection-molded with the inner and outer connecting rods 11 and connected to one end of the inner and outer connecting rods 11, forming a T-shape. The mixing disc 2 is provided with multiple water holes 3. These holes 3 include an upper reamer hole 8, a middle oblique hole 9, and a lower reamer hole 10. The diameters of the upper and lower reamer holes 8 and 10 are larger than those of the middle oblique hole 9. The edge of the middle oblique hole 9 extends in a direction that intersects with the upper and lower reamer holes 8 and 10, and the middle oblique hole 9 is an oblique hole.

[0032] The flexible funnel 4 is a flexible part in the shape of a funnel. The weld edge 13 at the top is connected to the bottom opening of the bag body 1 and is welded to the inner wall of the bag body 1. The lower end of the flexible funnel 4 is opened, and multiple annular sealing protrusions 12 are set on the inner side of the end. The bottom end of the flexible funnel 4 is sleeved on the inner and outer connecting rods 11. The corresponding positions of the depressions and protrusions are held from the outside by the clamp 5, and the flexible funnel 4 is fixed to the inner and outer connecting rods 11 so that the bag can be sealed. The mixing disk 2 is connected to the inner and outer connecting rods 11, which makes it easy to control the mixing disk 2 to move and stir the liquid medicine in the bag body 1 through the inner and outer connecting rods 11, and the mixing disk 2 is provided with a water hole 3. The liquid medicine flows smoothly through the water hole 3, and the mixing efficiency is higher and the mixing is more thorough.

[0033] The connection between the bottom ends of the inner and outer connecting rods 11 and the flexible funnel 4 is provided with multiple sealing recesses 15, which mate with the sealing protrusions 12. A bolt slot 14 is provided at the bottom end of the inner and outer connecting rods 11, which connects to the end of the motor connecting rod 6 on the motor 7. The flexible funnel 4 connects the bag body 1 and the inner and outer connecting rods 11, forming a funnel shape. As the inner and outer connecting rods 11 reciprocate up and down, it can accommodate the deformation and wrinkles caused by the upward and downward compression of the flexible funnel 4.

[0034] When the device is in use, the motor 7 drives the motor connecting rod 6 to reciprocate up and down, which in turn drives the inner and outer connecting rods 11 to reciprocate up and down. The mixing disc 2, connected to the inner and outer connecting rods 11, also moves together, with the amplitude of the movement adjusted according to the height of the contents. When the mixing disc 2 rises, the medicinal liquid passes through the upper reamer 8 of the water hole 3, and after passing through the middle oblique hole 9, the vertical downward movement of the medicinal liquid is changed to an oblique downward flow. The lower reamer 10 does not block the flow of the medicinal liquid. Similarly, when the mixing disc 2 descends, the medicinal liquid passes through the lower reamer 10 of the water hole 3, and after passing through the middle oblique hole 9, the vertical upward movement of the medicinal liquid is changed to an oblique upward flow. The upper reamer 8 does not block the flow of the medicinal liquid. The up and down displacement of the mixing disc 2 mixes the medicinal liquid, achieving a good mixing effect and high efficiency.

[0035] The embodiments described above are merely descriptions of preferred implementation methods of the present invention and do not limit the scope of the present invention. Without departing from the design spirit of the present invention, various modifications and improvements made by technical personnel in this field to the technical solution of the present invention should be included in the scope of protection determined by the claims of the present invention.

Claims

1. A disposable reaction bag with axial motion and mixing, comprising a bag body and a mixing device provided at the bottom of the bag body, characterized in that: The mixing device includes a mixing disk, inner and outer connecting rods, a motor, and a flexible funnel. The mixing disk is arranged inside the bag body, and the flexible funnel is arranged at the bottom of the bag body. One end of the inner and outer connecting rods is connected to the mixing disk, and the other end of the inner and outer connecting rods passes through the flexible funnel. The end of the other end of the inner and outer connecting rods is connected to the motor.

2. A disposable reaction bag for axial motion diversion mixing according to claim 1, characterized in that: The mixing disc is integrally injection-molded with the inner and outer connecting rods and is connected to one end of the inner and outer connecting rods. The overall shape is T-shaped. The mixing disc is provided with a plurality of water holes.

3. A disposable reaction bag for axial motion diversion mixing according to claim 2, characterized in that: The water hole includes an upper reaming hole, a middle oblique hole, and a lower reaming hole. The apertures of the upper reaming hole and the lower reaming hole are larger than the aperture of the middle oblique hole. The extension direction of the edge of the middle oblique hole intersects with the upper reaming hole and the lower reaming hole. The middle oblique hole is an oblique hole.

4. The disposable reaction bag for axial motion diversion mixing according to claim 1, characterized in that: The flexible funnel is a flexible part in the shape of a funnel, the welding edge at the top is connected to the bottom opening of the bag body and is welded to the inner wall of the bag body. The lower end of the flexible funnel has an opening, and multiple annular sealing protrusions are set on the inner side of the end.

5. A disposable reaction bag for axial motion-directed mixing according to claim 4, characterized in that: The bottom end of the flexible funnel is sleeved on the inner and outer connecting rods, and the flexible funnel and the inner and outer connecting rods are fixed by a clamp.

6. A disposable reaction bag for axial motion diversion mixing according to claim 5, characterized in that: A plurality of sealing connection recesses are provided at the connection between the bottom ends of the inner and outer connecting rods and the flexible funnel, and the sealing connection recesses are matched with the sealing protrusions.

7. The disposable reaction bag for axial motion diversion and mixing according to claim 1, characterized in that: The bottom ends of the inner and outer connecting rods are provided with bolt grooves, and the bolt grooves are connected to the ends of the motor connecting rods arranged on the motor.

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