Multifunctional automatic film covering device for microwell plate

Abstract

The utility model provides a multifunctional micropore plate automatic film covering device. The multifunctional micropore plate automatic film covering device comprises a film covering unit, a moving unit and a workbench. The film covering unit is arranged at one end of the workbench and connected with the moving unit, and the film covering unit slides on the workbench in a translation mode through the moving unit. Wherein the film covering unit comprises a film heat-sealing mechanism and a film pressing mechanism, the film heat-sealing mechanism and the film pressing mechanism are integrally arranged, the moving unit moves to the other end of the workbench to suck a plate sealing film, and the moving unit moves the plate sealing film to a consumable plate on the workbench for film heat-sealing treatment; and the film pressing mechanism conducts film pressing treatment on the consumable plate through the plate sealing film. According to the multifunctional automatic film covering device for the microwell plate, film absorbing, film pressing and film pulling treatment can be achieved at the same time, the sample treatment efficiency is greatly improved, and the size needed by the device is reduced.

Description

Technical Field

[0001] The present application belongs to the field of experimental technology, and in particular relates to a multifunctional microplate automatic coating device. Background Art

[0002] At present, viruses are usually detected using the fluorescent PCR method. The fluorescent PCR method refers to the addition of fluorescent groups to the PCR reaction system. As the PCR amplification proceeds, the reaction products continue to accumulate, and the intensity of the fluorescent signal also increases proportionally. Finally, the change in the amount of the product is monitored by the change in fluorescence intensity, thereby obtaining a fluorescent amplification curve graph for real-time detection of the PCR process. In the PCR process, a sealing plate is required to ensure the accuracy of the PCR test results. At this time, if the film is manually coated, it is inevitable that the sample will be contaminated, affecting the accuracy of the PCR test results. In the existing technology, film suction, film coating and film removal are often achieved by different equipment. This will affect the efficiency and required volume of the experiment. Utility Model Content

[0003] The purpose of this application is to provide a multifunctional microplate automatic laminating device to solve the technical problem of how to achieve multifunctional automatic laminating.

[0004] In the first aspect, the present application provides a multifunctional microplate automatic laminating device, comprising a laminating unit, a moving unit and a workbench; the laminating unit is arranged at one end of the workbench and connected to the moving unit, and the laminating unit slides horizontally on the workbench through the moving unit; wherein, the laminating unit comprises a heat-sealing film mechanism and a film pressing mechanism, and the heat-sealing film mechanism and the film pressing mechanism are integrally arranged, and the moving unit moves to the other end of the workbench to absorb the sealing film, and the sealing film is moved to the consumable plate on the workbench by the moving unit for heat-sealing film treatment; and the film pressing mechanism uses the sealing film to perform film pressing treatment on the consumable plate.

[0005] In an implementation of the first aspect, the moving unit includes a moving drive motor, a moving transmission belt, and two moving plates; the two moving plates are arranged on the moving transmission belt and are respectively located on both sides of the moving drive motor.

[0006] In an implementation of the first aspect, the two movable plates are respectively connected to two sides of the laminating unit, and the movable transmission belt drives the laminating unit to translate and slide on the workbench through the two movable plates.

[0007] In an implementation of the first aspect, the heat-sealing film mechanism includes a first support frame, a film absorbing plate and a first compression member; the first compression member is disposed between the film absorbing plate and the first support frame.

[0008] In an implementation of the first aspect, the first support frame includes a first fixed plate, a first lifting drive unit and a vacuum unit; a first fixing member is provided on the first fixed plate, and the first compression member is connected to the first fixed plate through the first fixing member.

[0009] In an implementation of the first aspect, the film-absorbing plate is hollow inside, and a plurality of adsorption holes are provided on the bottom, and the adsorption holes are distributed in an array.

[0010] In an implementation of the first aspect, the vacuum unit is connected to a pneumatic driving unit, and the pneumatic driving unit drives the vacuum unit to extract gas from the film-absorbing plate, so that a negative pressure is formed in the adsorption holes.

[0011] In an implementation of the first aspect, the film pressing mechanism includes a second support frame, a film pressing plate and a second compression member; the second compression member is arranged between the film pressing plate and the second support frame.

[0012] In an implementation of the first aspect, the second support frame includes a second fixing plate and a second lifting drive unit; a second fixing piece is provided on the second fixing plate, and the second compression piece is connected to the second fixing plate through the second fixing piece.

[0013] In an implementation of the first aspect, a mounting seat is provided on the workbench, and the consumable plate is placed on the workbench through the mounting seat.

[0014] As described above, the multifunctional microplate automatic coating device described in the present application has the following beneficial effects: it can simultaneously realize film suction, film pressing and film removal processing, greatly improving the sample processing efficiency and reducing the volume required for the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 Shown is a structural schematic diagram of a multifunctional microplate automatic coating device described in an embodiment of the present application.

[0016] Figure 2 Shown is a schematic diagram of the internal structure of a multifunctional microplate automatic coating device described in an embodiment of the present application.

[0017] Figure 3 Shown is a schematic diagram of the internal structure of a multifunctional microplate automatic coating device described in an embodiment of the present application.

[0018] Figure 4 Shown is a structural schematic diagram of a mobile unit described in an embodiment of the present application.

[0019] Figure 5Shown is a structural schematic diagram of a mobile unit described in an embodiment of the present application.

[0020] Figure 6 Shown is a structural schematic diagram of a coating unit described in an embodiment of the present application.

[0021] Figure 7 Shown is a structural schematic diagram of a coating unit described in an embodiment of the present application.

[0022] Component number description

[0023] 1 Laminating unit

[0024] 11. Heat sealing film mechanism

[0025] 111 First support frame

[0026] 111 First fixed plate

[0027] 1112 First lifting drive unit

[0028] 112 film absorbing plate

[0029] 113 First compression element

[0030] 12. Film pressing mechanism

[0031] 121 Second support frame

[0032] 1211 includes a second fixing plate

[0033] 1212 Second lifting drive unit

[0034] 122 laminated plate

[0035] 123 Second compression element

[0036] 2 mobile units

[0037] 21 Mobile drive motor

[0038] 22 Mobile drive belt

[0039] 23 Mobile Board

[0040] 3 Workbench

[0041] 31 Mounting Block

[0042] A1 First fixing piece

[0043] A2 Second fixing piece DETAILED DESCRIPTION

[0044] The following describes the embodiments of the present application through specific examples. Those skilled in the art can easily understand the other advantages and effects of the present application from the content disclosed in this specification. The present application can also be implemented or applied through other different specific embodiments. The details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present application. It should be noted that the following embodiments and features in the embodiments can be combined with each other unless they conflict.

[0045] It should be noted that the illustrations provided in the following embodiments are only schematic illustrations of the basic concept of the present application. Therefore, the illustrations only show components related to the present application and are not drawn according to the number, shape and size of components in actual implementation. In actual implementation, the type, quantity and proportion of each component can be changed at will, and the component layout type may also be more complicated.

[0046] In addition, the descriptions of "first", "second", etc. in this application are for descriptive purposes only and should not be understood as indicating or implying their relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined as "first" or "second" may explicitly or implicitly include at least one of such features. In addition, the technical solutions between the various embodiments can be combined with each other, but this must be based on the fact that they can be implemented by ordinary technicians in this field. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0047] The following embodiments of the present application provide a multifunctional microplate automatic laminating device, which solves the technical problem of how to achieve multifunctional automatic laminating.

[0048] The principle and implementation of a multifunctional microplate automatic coating device of this embodiment will be described in detail below with reference to the accompanying drawings, so that those skilled in the art can understand the multifunctional microplate automatic coating device of this embodiment without creative work.

[0049] See also Figures 1 to 7 As shown, this embodiment provides a multifunctional microplate automatic coating device, including a coating unit 1, a moving unit 2 and a workbench 3; the coating unit 1 is arranged at one end of the workbench 3 and connected to the moving unit 2, and the coating unit 1 slides horizontally on the workbench 3 through the moving unit 2.

[0050] See also Figures 4 and 5 As shown, the moving unit 2 includes a moving drive motor 21 , a moving transmission belt 22 and two moving plates 23 ; the two moving plates 23 are arranged on the moving transmission belt 22 and are respectively located on both sides of the moving drive motor 21 .

[0051] For further information, please refer to Figures 1 to 5 As shown, the two movable plates 23 are respectively connected to both sides of the laminating unit 1 , and the movable transmission belt 22 drives the laminating unit 1 to slide horizontally on the workbench 3 through the two movable plates 23 .

[0052] Also, please continue to read Figure 4 As shown, the workbench 3 is provided with a mounting seat 31, and the consumable plate is placed on the workbench 3 through the mounting seat 31. In some embodiments, the consumable plate can be a microplate, a nucleic acid plate, a PCR plate, or other consumables that need to be sealed.

[0053] Please continue reading Figures 1 to 7 As shown, the laminating unit 1 includes a heat-sealing film mechanism 11 and a film pressing mechanism 12, and the heat-sealing film mechanism 11 and the film pressing mechanism 12 are arranged in one piece, and are moved to the other end of the workbench 3 by the moving unit 2 to absorb the sealing film, and the sealing film is moved to the consumable plate on the workbench 3 by the moving unit 2 for heat-sealing film treatment; and the film pressing mechanism 12 uses the sealing film to press the consumable plate.

[0054] Specifically, the laminating unit 1 provided in the embodiment of the present application is actually integrated with a heat sealing film mechanism 11 and a film pressing mechanism 12, so as to simultaneously absorb the sealing film and use the sealing film to perform heat sealing and pressing on the consumable plate that needs to be sealed.

[0055] The following will be Figures 1 to 7 Taking the heat sealing film mechanism 11 and the film pressing mechanism 12 in the above embodiment as an example, the heat sealing film mechanism 11 and the film pressing mechanism 12 in the above embodiment are further explained.

[0056] Please continue reading Figures 6 and 7 As shown, the heat-sealing film mechanism 11 includes a first support frame 111, a film-absorbing plate 112, and a first compression member 113. The first compression member 113 is disposed between the film-absorbing plate 112 and the first support frame 111. By disposing the compression member 113 between the film-absorbing plate 112 and the first support frame 111, when the first support frame 111 descends, the compression member 113 is compressed, causing the first support frame 111 to contact the film-absorbing plate 112, thereby achieving film absorption or removal.

[0057] For further information, please refer to Figure 2 、 Figure 6 and Figure 7 As shown, the first support frame 111 includes a first fixed plate 1111, a first lifting drive unit 1112 and a vacuum unit; a first fixing member A1 is provided on the first fixed plate 1111, and the first compression member 113 is connected to the first fixed plate 1111 through the first fixing member A1.

[0058] In some embodiments, the first lifting drive unit 1112 can select a drive motor.

[0059] Specifically, the film-absorbing plate 112 is hollow inside, and a plurality of adsorption holes are provided on the bottom, and the adsorption holes are distributed in an array.

[0060] In some embodiments, the adsorption holes provided on the bottom of the membrane absorption plate 112 correspond one-to-one to the circular holes on the nucleic acid cover plate to be sealed.

[0061] Specifically, the vacuum pumping unit is connected to the air pressure driving unit, and the air pressure driving unit drives the vacuum pumping unit to extract the gas inside the film suction plate 112, so that the adsorption holes provided at the bottom form a negative pressure.

[0062] In some embodiments, the film suction working principle of the heat-sealing film mechanism 11 is as follows: when the microplate needs to be sealed, the heat-sealing film mechanism 11 moves to the other end of the workbench 3 through the moving unit 2, and absorbs the sealing film within the planned area frame at the designated position. Specifically, when reaching the designated position, the first lifting drive unit 1112 on the first support frame 111 of the heat-sealing film mechanism 11 drives the first support frame 111 to descend. At this time, the first fixed plate 1111 will compress the first compression member 113 during the descent process, thereby driving the film suction plate 112 to descend synchronously. When the film suction plate 112 descends to the designated height, the air pressure drive unit will drive the vacuum unit to extract the gas inside the film suction plate 112, so that the adsorption holes provided at the bottom form a negative pressure. At this time, the film suction plate 112 will absorb the sealing film in the designated area and move to the microplate again through the moving unit 2.

[0063] In some embodiments, the heat-sealing film mechanism 11 can be equipped with a heating unit. When the film-absorbing plate 112 of the heat-sealing film mechanism 11 absorbs the sealing film and moves it to the microplate, the heat-sealing film mechanism 11 then uses the heating unit to heat-seal the film. In other embodiments, the mounting base 31 on the workbench 3 can also be configured as a heating base to achieve the same heating and film pressing effect.

[0064] In other embodiments, the heat-sealing film mechanism 11 provided in the present application can actually also realize film pulling. The film pulling working principle of the heat-sealing film mechanism 11 is as follows: when the microporous plate that has completed the film coating process is processed through subsequent steps and needs to be pulled out, the microporous plate is placed back on the mounting seat 31 of the workbench 3 and clamped and fixed. Afterwards, the heat-sealing film mechanism 11 is moved to the top of the place through the moving unit 2, and the first lifting drive unit 1112 drives the first support frame 111 to descend. At this time, the first fixed plate 1111 will compress the first compression member 113 during the descent process, and thereby drive the film absorbing plate 112 to descend synchronously. When the film absorbing plate 112 contacts the microporous plate after the film is applied, the air pressure drive unit will drive the vacuum unit to extract the gas inside the film absorbing plate 112, so that the adsorption holes provided at the bottom form a negative pressure. At this time, the film absorbing plate 112 will absorb the sealing film on the surface of the microporous plate to realize the film pulling function.

[0065] Please continue reading Figures 6 and 7 As shown, the film pressing mechanism 12 includes a second support frame 121 , a film pressing plate 122 and a second compression member 123 ; the second compression member 123 is disposed between the film pressing plate 122 and the second support frame 121 .

[0066] For further information, please refer to Figures 6 and 7 As shown, the second support frame 121 includes a second fixing plate 1211 and a second lifting drive unit 1212; a second fixing member A2 is provided on the second fixing plate 1211, and the second compression member 123 is connected to the second fixing plate 1211 through the second fixing member A2.

[0067] In some embodiments, the second lifting drive unit 1212 can select a drive motor.

[0068] In some embodiments, the working principle of the film pressing mechanism 12 is as follows: after the film suction plate 112 of the heat-sealing film mechanism 11 absorbs the sealing film and moves the sealing film to the microplate for heat-sealing, the film pressing mechanism 12 moves to the top of the microplate via the moving unit 2. When the designated position is reached, the second lifting drive unit 1212 on the second support frame 121 of the film pressing mechanism 12 drives the second support frame 121 to descend. At this time, the second fixing plate 1211 will compress the second compression member 123 during the descent process, thereby driving the film pressing plate 122 to descend synchronously, and the downward pressure presses the sealing film onto the microplate to complete the film pressing process.

[0069] In some embodiments, the multifunctional microplate automatic laminating device provided in the present application further includes an infrared sensor, which is used to sense whether the laminating unit has reached a designated area.

[0070] The multifunctional microplate automatic coating device provided in the embodiment of the present application can simultaneously realize film suction, film pressing and film removal processing, greatly improving the sample processing efficiency and reducing the volume required for the device.

[0071] In summary, the present invention effectively overcomes various shortcomings of the prior art and has high industrial utilization value.

[0072] The descriptions of the processes or structures corresponding to the above figures have different emphases. For parts that are not described in detail in a certain process or structure, please refer to the relevant descriptions of other processes or structures.

[0073] The above embodiments are merely illustrative of the principles and effects of this application and are not intended to limit this application. Anyone skilled in the art may modify or alter the above embodiments without departing from the spirit and scope of this application. Therefore, all equivalent modifications or alterations made by one of ordinary skill in the art without departing from the spirit and technical concepts disclosed in this application shall be covered by the claims of this application.

Claims

1. A multifunctional microplate automatic laminating device, characterized in that: include: A laminating unit, a moving unit and a workbench; the laminating unit is arranged at one end of the workbench and connected to the moving unit, and the laminating unit slides horizontally on the workbench through the moving unit; wherein, The laminating unit includes a heat-sealing film mechanism and a film pressing mechanism, which are integrally arranged. The moving unit moves to the other end of the workbench to absorb the sealing film, and the moving unit moves the sealing film to the consumable plate on the workbench for heat-sealing film processing; and The laminating mechanism performs laminating processing on the consumable plate using the sealing film; in The heat-sealing film mechanism includes a first supporting frame, a film-absorbing plate and a first compression member; the first compression member is arranged between the film-absorbing plate and the first supporting frame.

2. The multifunctional microplate automatic coating device according to claim 1, characterized in that: The moving unit includes a moving drive motor, a moving transmission belt and two moving plates; the two moving plates are arranged on the moving transmission belt and are respectively located on both sides of the moving drive motor.

3. The multifunctional microplate automatic coating device according to claim 2, characterized in that: The two movable plates are respectively connected to two sides of the laminating unit, and the movable transmission belt drives the laminating unit to translate and slide on the workbench through the two movable plates.

4. The multifunctional microplate automatic laminating device according to claim 1, characterized in that: The first support frame includes a first fixing plate, a first lifting drive unit and a vacuum unit; a first fixing member is provided on the first fixing plate, and the first compression member is connected to the first fixing plate through the first fixing member.

5. The multifunctional microplate automatic coating device according to claim 4, characterized in that: The film absorbing plate is hollow inside and has a plurality of adsorption holes arranged on the bottom, and the adsorption holes are distributed in an array.

6. The multifunctional microplate automatic coating device according to claim 5, characterized in that: The vacuum pumping unit is connected to the air pressure driving unit, and the air pressure driving unit drives the vacuum pumping unit to extract the gas inside the film suction plate, so that the adsorption holes form a negative pressure.

7. The multifunctional microplate automatic coating device according to claim 1, characterized in that: The film pressing mechanism includes a second support frame, a film pressing plate and a second compression member; the second compression member is arranged between the film pressing plate and the second support frame.

8. The multifunctional microplate automatic coating device according to claim 7, characterized in that: The second support frame includes a second fixing plate and a second lifting drive unit; the second fixing plate is provided with a second fixing piece, and the second compression piece is connected to the second fixing plate through the second fixing piece.

9. The multifunctional microplate automatic coating device according to claim 1, characterized in that: The workbench is provided with a mounting seat, and the consumable plate is arranged on the workbench through the mounting seat.

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