Cell screen with novel structure
By designing a cell screen with a bottom outlet at the inclined surface and a curve inverted structure, the problems of water membrane sealing and bubble formation are solved, and the smooth filtration of cell suspension and the protection of cell activity are achieved.
Patent Information
- Application Number
- CN202422224478.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-11
- Publication Date
- 2025-08-26
- Estimated Expiration
- 2034-09-11
AI Technical Summary
The existing cell screen is prone to form a water membrane seal during use, resulting in high pressure in the centrifuge tube, the cell suspension cannot pass smoothly, and the bottom outlet level is set to cause the cell suspension to form droplets in the center of the screen, affecting cell activity.
A new structure of cell sieve mesh was designed, with the bottom outlet being an inclined screen, which had a perpendicular angle of 60°-70° to the cell sieve body, and a arc inclined inclined at the top opening, increasing the gap with the centrifugal tube wall. A non-standard circular structure was adopted, and the inclined screen guided the cell suspension to flow down the centrifugal tube wall, and the arc inclined inclined is convenient for gas discharge.
It effectively reduces cell damage, ensures smooth passage of cell suspension, avoids bubble formation, and improves cell activity.
Smart Images

Figure CN223268637U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell screening, and more particularly to a cell screen with a novel structure. Background Art
[0002] In cell experiments, cell sieves are often needed to screen cell suspensions. During the use of common cell sieves, the cell suspension often forms a water film seal at the top opening of the cell sieve and the mouth of the centrifuge tube, resulting in the inability to discharge the air in the centrifuge tube normally, forming high pressure in the centrifuge tube, and the cell suspension cannot pass through the cell sieve smoothly.
[0003] Secondly, the bottom outlet screen of the common cell screen is set horizontally. After the cell suspension passes through the screen smoothly, it will form droplets in the center of the screen and flow into the centrifuge tube, causing bubbles in the cell suspension in the centrifuge tube, thereby affecting cell activity. Utility Model Content
[0004] The purpose of the utility model is to provide a cell screen with a new structure, in order to solve the technical problems existing in the background technology.
[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:
[0006] A novel cell screen structure, comprising:
[0007] A cell sieve tube body, wherein the top of the cell sieve tube body is provided with a top opening, and the bottom of the cell sieve tube body is provided with a bottom outlet; the top opening and the bottom outlet are connected;
[0008] a first handle mounted on one side of the top opening;
[0009] The body of the cell sieve tube forms an arc-shaped indentation on the opposite side of the handle;
[0010] a second handle, the second handle being arranged on the side of the inward arc;
[0011] The inclined screen is arranged on the bottom outlet, and the high end of the inclined surface is on the same side as the arc depression.
[0012] In some embodiments, the lower end of the inclined screen is disposed on one side of the first handle.
[0013] In some embodiments, the inclined screen forms an angle of 60°-70° with respect to the vertical direction of the cell sieve tube body.
[0014] In some embodiments, two second handles are provided, and are respectively disposed at the two ends of the inward arc.
[0015] In some embodiments, the length of the first handle is longer than the length of the second handle.
[0016] In some embodiments, the pore size of the inclined screen is 100-500 μm.
[0017] In some embodiments, the cell screen tube body includes a cell screen frame and a sidewall screen disposed on the cell screen frame.
[0018] Compared with the prior art, the present invention has the following beneficial effects:
[0019] 1. This new cell sieve has an inclined screen at the bottom outlet. The inclined screen at the bottom outlet forms an angle of 60°-70° with the vertical direction of the cell sieve tube. When filtering the cell suspension, under the action of gravity, the cell suspension passing through the screen will flow down the centrifuge tube wall quickly and smoothly without generating bubbles, which greatly reduces damage to the cells.
[0020] 2. This new cell sieve adopts a non-standard circular structure. An arc-shaped indentation is formed on the opposite side of the first handle, forming a gap between the cell sieve tube body and the centrifuge tube wall. When filtering the cell suspension, the gas in the centrifuge tube can be discharged smoothly. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1 This is a schematic diagram of the structure of the novel cell screen of the present application;
[0022] Figure 2 This is a top view of the novel cell screen structure of the present application.
[0023] Illustration: 1- side wall screen, 2- first handle, 3- second handle, 4- inclined screen, 5- cell screen frame. DETAILED DESCRIPTION
[0024] In order to make the purpose, technical solutions and advantages of the present application clearer, the technical solutions in the embodiments of the present application will be described in more detail below in conjunction with the drawings in the preferred embodiments of the present application. In the drawings, the same or similar reference numerals throughout represent the same or similar parts or parts with the same or similar functions. The described embodiments are part of the embodiments of the present application, not all of the embodiments. The embodiments described below with reference to the drawings are exemplary and are intended to be used to explain the present application, and should not be understood as limitations on the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of this application.
[0025] The embodiments of the present application are described in detail below with reference to the accompanying drawings.
[0026] In the description of this application, it should be noted that, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood in a broad sense. For example, they may refer to a fixed connection, an indirect connection via an intermediate medium, internal communication between two components, or an interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on the specific circumstances.
[0027] In the description of this application, it should be understood that the terms "upper", "lower", "front", "back", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are orientations or positional relationships based on the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on this application.
[0028] In addition, the terms "comprises" and "having" and any variations thereof are intended to cover a non-exclusive inclusion; for example, a process, method, system, product, or display that comprises a series of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, product, or display.
[0029] The following will be combined Figure 1-Figure 2 , a novel cell screen structure involved in the examples of the present application is described in detail. It is worth noting that the following examples are only used to explain the present application and do not constitute a limitation of the present application.
[0030] Embodiment 1:
[0031] like Figure 1-2 As shown, a cell screen of a novel structure comprises: a cell screen tube body, a first handle 2, a second handle 3, and a slanted screen 4. The top of the cell screen tube body is provided with a top opening, and the bottom of the cell screen tube body is provided with a bottom outlet; the top opening and the bottom outlet are connected; the first handle 2 is installed on one side of the top opening; the cell screen tube body forms an arc indentation on the opposite side of the handle; the second handle 3 is arranged on one side of the arc indentation; the slanted screen 4 is arranged on the bottom outlet, and the high end of the slope is on the same side as the arc indentation; the low end of the slanted screen 4 is arranged on one side of the first handle 2.
[0032] The bottom outlet screen is a sloped screen 4, which forms a 60-70° angle with the vertical direction of the cell sieve tube. When filtering the cell suspension, gravity guides the cell suspension passing through the sloped screen 4 to flow quickly and smoothly along the centrifuge tube wall, eliminating the generation of bubbles and significantly reducing damage to the cells. This novel cell sieve structure also adopts a non-standard circular structure. The opposite side of the cell sieve handle forms an arc-shaped indentation, which increases the gap between the cell sieve tube and the centrifuge tube wall. This allows for smooth discharge of gas from the centrifuge tube during filtration.
[0033] In some embodiments, the second handles 3 are provided with two and are respectively arranged at the two ends of the arc inward. When in use, the three handles are used to maintain the balance of the cell sieve tube body.
[0034] In some embodiments, the length of the first handle 2 is longer than the length of the second handle 3, so as to facilitate single-handed taking and placing via the first handle 2.
[0035] The screen mesh used in this invention is made of suitable materials such as nylon membrane or polyester mesh with different pore sizes, with the pore size of the nylon membrane or polyester mesh ranging from 100 to 500 μm. The cell sieve tube body includes a cell sieve frame 5 and a sidewall screen mesh 1 disposed on the cell sieve frame 5. The sidewall screen mesh 1 has the same structure and material as the screen mesh.
[0036] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.
Claims
1. A novel cell screen, characterized in that: include: A cell sieve tube body, wherein the top of the cell sieve tube body is provided with a top opening, and the bottom of the cell sieve tube body is provided with a bottom outlet; the top opening and the bottom outlet are connected; a first handle mounted on one side of the top opening; The body of the cell sieve tube forms an arc-shaped indentation on the opposite side of the handle; a second handle, the second handle being arranged on the side of the inward arc; The inclined screen is arranged on the bottom outlet, and the high end of the inclined surface is on the same side as the arc depression.
2. A novel cell screen according to claim 1, characterized in that: The lower end of the inclined screen is arranged on one side of the first handle.
3. The novel cell screen according to claim 1, characterized in that: The inclined screen forms an angle of 60°-70° with the vertical direction of the cell sieve tube body.
4. A novel cell screen according to claim 1, characterized in that: There are two second handles, which are respectively arranged at the two ends of the inward arc.
5. The novel cell screen according to claim 1, characterized in that: The length of the first handle is longer than that of the second handle.
6. The novel cell screen according to claim 1, characterized in that: The aperture of the inclined screen is 100-500um.
7. A novel cell screen according to any one of claims 1 to 6, characterized in that: The cell screen tube body comprises a cell screen frame and a side wall screen arranged on the cell screen frame.