Slide plate for microscope scanning of dyeing sealing sheet

By designing a glass plate with a frameless suspended structure, the slide slides slides on the plate are solved, and the problems of cross-contamination of reagents and complex operations are achieved, and the integration of dyeing, sealing and scanning is achieved, which improves operating efficiency and adaptability.

CN223284462UActive Publication Date: 2025-08-29SHANGHAI BORTON MEDICAL EQUIP CO LTD
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Patent Information

Application Number
CN202422745538.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-12
Publication Date
2025-08-29
Estimated Expiration
2034-11-12

AI Technical Summary

Technical Problem

The existing staining methods have problems such as cross-contamination of reagents, complex and time-consuming operation, and the inability to integrate dyeing, sealing and scanning. The slides need to be transferred multiple times, and the adaptability is poor.

Method used

A glass plate with a frameless suspended structure is designed. The end of the slide is a clamping part and the other end is a cell sample part. The clamping structure includes an upper support plate and a side support plate, with a through groove and a notch. The glass plate can slide on the plate to realize integrated operations of immersion dyeing, sealing and scanning.

Benefits of technology

Reduce cross-contamination between reagent cylinders, simplify operation procedures, reduce cleaning time, and ensure that the slides remain on the plate throughout the whole process. It is suitable for manual and automated equipment and improve efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of cell pathology sample pretreatment, and provides a slide plate for dyeing sealing sheet microscope scanning, the slide plate comprises a frame body and a clamping structure, the frame body comprises an upper support plate and a pair of side support plates, the upper support plate is provided with a row of placing positions at intervals, the placing positions are suitable for placing slides, the pair of side support plates are arranged at two ends of the upper support plate, and the clamping structure is arranged on the side support plates. The frame body is of a frameless suspended structure; the clamping structure is arranged on the upper supporting plate and is suitable for clamping the slide in the length direction or the thickness direction or the width direction of the placing position. The label taking end of the slide is a clamping part, the other end of the slide is a cell sample part, and the slide is of a frameless suspended structure, so that soaking type dyeing, less liquid staining and convenient and comfortable taking can be realized, meanwhile, the integrated full-process operation of dyeing, slide sealing and scanning can be realized, the slide is fixed on the slide plate in the whole process and does not need to be transferred, the time is conveniently saved, and the working efficiency is improved. And the novel slide plate is easy to use by both manual and full-automatic equipment.
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Description

Technical Field

[0001] The utility model relates to the field of cytopathology sample pre-treatment, and further relates to a glass slide plate used for staining, sealing and microscope scanning. Background Art

[0002] Existing dyeing methods: There are two main types: dip dyeing and drip dyeing.

[0003] Immersion staining involves inserting slides into a hanging basket, which is then moved between the various staining reagent vats. After staining, the slides are removed, sealed, and then inserted back into the hanging basket. They are then removed from the basket and placed on a cooling plate to dry before being examined under a microscope. The main issues with this hanging basket staining method include: excessive liquid buildup between the basket frame and the slides, which can carry reagents from one vat to the next, leading to cross-contamination. Furthermore, the slides must be moved multiple times during the staining, sealing, and examination processes, making the operation complex and time-consuming.

[0004] Drip staining is the process of dripping reagents onto a glass slide on a glass slide plate. This type of glass slide plate is double-row symmetrical and has a full-frame structure. It is only suitable for dripping reagents onto a glass slide and cannot insert the glass slide into a reagent tank for staining. This type of glass slide plate is inconvenient to take and place, and there is no large notch for taking and placing. The glass slide has to be picked up with fingers and the edge of the glass slide, which makes the operation uncomfortable.

[0005] Existing hanging baskets and slides are not suitable for microscope scanning. Slides must be removed from the slides one by one and transferred to the microscope platform. This makes it impossible to use a single carrier for the entire staining, sealing, and scanning process. It also makes it impossible to keep cell-sample slides fixed on a single carrier throughout the entire process. Multiple slide transfers are required, which is complex, time-consuming, and cumbersome. Utility Model Content

[0006] In response to the above technical problems, the purpose of the utility model is to provide a glass slide plate for staining, sealing and microscope scanning, which can realize immersion staining, less liquid, and is easy and comfortable to hold. At the same time, it can realize the integrated whole process operation of staining, sealing and scanning. The glass slide does not move on the glass slide plate throughout the whole process and does not need to be transferred, which is convenient and time-saving. It is a new type of glass slide plate that is easy to use with both manual and fully automated equipment.

[0007] The purpose of the utility model is to provide a glass slide plate, in which the glass slide picking label end is a clamping part, and the other end of the glass slide is a cell sample part. It is a frameless suspended structure, which is convenient for inserting the glass slide sample part into the reagent cylinder, and less liquid is carried when moving back and forth between various reagent cylinders, reducing cross-contamination of test liquids between reagent cylinders and reducing cleaning time. At the same time, it is convenient to operate directly on the cell part when dripping glue to seal the slide, without avoiding the glass slide plate frame.

[0008] In order to achieve the above-mentioned object, the utility model provides a glass slide plate for microscope scanning of stained coverslips, comprising a frame and a clamping structure, wherein the frame comprises an upper support plate and a pair of side support plates, wherein a row of placement positions are provided on the upper support plate at intervals, wherein the placement positions are suitable for placing glass slides, and wherein the placement positions are provided with a taking space, wherein a pair of side support plates are provided at both ends of the upper support plate, and the frame is a frameless suspended structure;

[0009] The clamping structure is arranged on the upper support plate and is suitable for clamping the glass slide along the length direction, thickness direction or width direction of the placement position. The label holding end of the glass slide is the clamping part, and the other end of the glass slide is the cell sample part.

[0010] In some embodiments, the upper support plate is provided with a plurality of through grooves, the clamping portion of the glass slide is adapted to be inserted into the through grooves along the length direction of the placement position, the top of the through groove is provided with an upper notch, the upper notch exposing the upper surface of the clamping portion of the glass slide, and the clamping structures are provided on both sides of the upper notch in the width direction and are relatively located above the clamping portion of the glass slide;

[0011] A lower notch is further provided at the bottom of the through groove, wherein the lower notch exposes the lower surface of the clamping portion of the glass slide, and the upper notch and the lower notch form the taking space.

[0012] In some embodiments, the clamping structure includes a plurality of upper stop cards and a plurality of elastic pressure holding members arranged at intervals, a pair of the upper stop cards are arranged at intervals at the top of the through groove, and the elastic pressure holding members are arranged below the upper stop cards and are suitable for clamping the clamping part of the glass slide along the thickness direction of the placement position.

[0013] In some embodiments, the lower notch is U-shaped, and the upper stopper on at least one side of the upper notch does not exceed the bottom of the lower notch, so that after pushing the glass slide, one side or both sides of the glass slide can move upward away from the upper stopper, making it convenient to remove the glass slide without scratching the cover glass on the glass slide that has just been sealed with glue and the glue has not yet dried.

[0014] In some embodiments, the clamping structure includes an elastic upper stopper and a long slot upper stopper, wherein the elastic upper stopper and the long slot upper stopper are respectively arranged on both sides of the width direction of the upper notch and are relatively located above the clamping portion of the glass slide;

[0015] The elastic upper stopper is elastically connected to the end of the upper support plate, and a buffer bent hole is further provided at the connection between the elastic upper stopper and the upper support plate, so that the elastic upper stopper is suitable for elastically abutting the upper surface of the clamping part of the glass slide, and a card slot is provided at the bottom of the long slot upper stopper, and the card slot is connected to the through slot;

[0016] When the glass slide is pushed into the through slot, the elastic upper stopper elastically presses the glass slide and drives the glass slide and the long slot upper stopper into the slot.

[0017] In some embodiments, a short stop is provided on one side of the elastic upper stop close to the long slot upper stop, and the short stop does not exceed the bottom of the lower notch. The purpose is that when the glass slide is taken out, the upper part of the glass slide is already out of the short stop when the glass slide is pushed forward to the bottom of the lower notch, and the operator can then take the glass slide out upwards.

[0018] In some embodiments, the clamping structure includes an upper pressing plate, a first elastic member, and a baffle, wherein the upper pressing plate is arranged on both sides of the placement position in the width direction, the upper pressing plate includes a pressing portion and an elastic portion, the pressing portion is suitable for clamping the glass slide along the thickness direction of the placement position, the upper support plate is provided with a movable groove, the elastic portion is suitable for extending into the movable groove, and the elastic portion is provided with a snap groove on a side away from the pressing portion, and the baffle is suitable for mounting in the snap groove;

[0019] The first elastic member elastically connects the baffle and the bottom of the upper support plate, so that the pressing portion of the upper pressing plate and the upper support plate clamp one end of the glass slide along the thickness direction of the placement position under the action of the first elastic member.

[0020] In some embodiments, the clamping structure includes a spring clip and a fixing column, the through groove is provided on the upper support plate, the end of the through groove is provided with abutting surfaces, the abutting surfaces are suitable for abutting with the ends of the glass slide, the spring clips are spaced apart at both ends in the width direction of the through groove and are suitable for clamping both sides of the glass slide in the width direction, the upper surface of the upper support plate is provided with a fixing groove seat, the spring clip is installed on the two side walls of the fixing groove seat through the fixing column, so that the spring clip is suitable for clamping the glass slide along the thickness direction of the placement position.

[0021] In some embodiments, the clamping structure includes an elastic rod and a second elastic member, the through groove is provided on the upper support plate, and the end of the through groove is provided with an abutting slope, and the abutting slope is suitable for clamping one end of the glass slide; the elastic rod passes through the upper support plate along the length direction of the placement position, and the elastic rod includes an elastic end and a clamping end, and the second elastic member is provided between the elastic end and the side of the upper support plate away from the placement position, and the clamping end is provided with a barb, and the barb is suitable for clamping the other end of the glass slide, so that the abutting slope and the barb of the elastic rod clamp the glass slide along the length direction of the placement position.

[0022] Compared with the prior art, the glass slide plate for staining and sealing microscope scanning provided by the present invention has at least one of the following beneficial effects:

[0023] 1. The label end of the slide is the clamping part, and the other end of the slide is the cell sample part. It is a frameless suspended structure, which makes it convenient to insert the slide sample part into the reagent tank to achieve immersion staining. When moving back and forth between various reagent tanks, less liquid is carried, which reduces cross-contamination of test solutions between reagent tanks and reduces cleaning time. At the same time, it is convenient to operate directly on the cell part when dripping glue and sealing, without avoiding the slide plate frame. The whole process of staining, sealing, drying, scanning, etc. can be completed on the slide plate. The slide does not move on the slide plate throughout the whole process, and there is no need to transfer the slide additionally, saving time and effort.

[0024] 2. The frame is suspended, and the end of the slide away from the label is suspended, which makes it easy to insert the cell part of the slide into the liquid in the staining tank. In this way, only the slide is stained with liquid, and the frame and gaps are not stained with liquid, avoiding carrying the reagent to the next tank of reagent and contaminating and diluting the next tank of reagent.

[0025] 3. The upper support plate is provided with an upper notch and a lower notch, so that the upper and lower surfaces of the glass slide clamping parts are exposed through the upper notch and the lower notch, making it convenient to pinch the glass slide clamping parts up and down to insert or push the glass slide into or out of the fixed slot, making it convenient and comfortable to take and put.

[0026] 4. This application realizes a new type of glass slide that is easy to use with both manual and fully automated equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The preferred embodiments will be described below in a clear and understandable manner with reference to the accompanying drawings to further illustrate the above-mentioned characteristics, technical features, advantages and implementation methods of the present invention.

[0028] Figure 1 It is a structural diagram of the frame;

[0029] Figure 2 It is a structural diagram of the placement position;

[0030] Figure 3 It is a structural diagram of the clamping structure;

[0031] Figure 4 It is a detailed view of the elastic holding member;

[0032] Figure 5 is a structural diagram of a clamping structure in another embodiment;

[0033] Figure 6 This is a structural diagram of the elastic upper baffle;

[0034] Figure 7 It is the position diagram of the upper pressure plate;

[0035] Figure 8 is a cross-sectional view of the upper pressure plate;

[0036] Figure 9 It is a structural diagram of the spring clip;

[0037] Figure 10 This is a detailed view of the spring clip;

[0038] Figure 11 It is the structural diagram of the elastic rod;

[0039] Figure 12 This is a cross-sectional view of the elastic rod.

[0040] Description of Figure Numbers:

[0041] Frame 1, placement position 10, upper support plate 11, through slot 110, upper notch 111, lower notch 112, side support plate 12, lifting rod 121,

[0042] Clamping structure 2, upper block 21, elastic pressing member 22,

[0043] Elastic upper stopper 31, short stopper 311, long slot upper stopper 32, slot 321, buffer bend hole 33,

[0044] Upper pressing plate 41, pressing portion 411, elastic portion 412, buckle groove 413, first elastic member 42, baffle 43, movable groove 44,

[0045] Spring clip 51, fixing column 52, abutting surface 53, fixing groove seat 54, fixing groove 55,

[0046] Elastic rod 61, elastic end 611, clamping end 612, barb 613, second elastic member 62, abutting inclined surface 63,

[0047] Glass slide 7, clamping portion 71, cell sample portion 72. DETAILED DESCRIPTION

[0048] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the specific implementation methods of the present invention will be described below with reference to the accompanying drawings. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings and other implementation methods can be obtained based on these drawings without inventive work.

[0049] To simplify the drawings, only the parts relevant to the utility model are schematically shown in each figure; they do not represent the actual structure of the product. Furthermore, to simplify the drawings and facilitate understanding, in some figures, only one of the components with the same structure or function is schematically depicted or labeled. In this document, "one" not only means "only one" but also "more than one."

[0050] It should be further understood that the term "and / or" used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

[0051] It should be noted that, unless otherwise specified or limited, the terms "mounted," "connected," and "connected" should be understood broadly. For example, they can refer to fixed, detachable, or integral connections; mechanical or electrical connections; direct or indirect connections through an intermediary; and internal communication between two components. Those skilled in the art will understand the specific meanings of these terms in this utility model based on the specific circumstances.

[0052] In addition, in the description of this application, the terms "first", "second", etc. are only used to distinguish the description and should not be understood as indicating or implying relative importance. It should be noted that the above embodiments can be freely combined as needed. The above are only preferred implementations of the present utility model. It should be pointed out that for ordinary technicians in this technical field, without departing from the principles of the present utility model, several improvements and modifications can be made, and these improvements and modifications should also be considered as the scope of protection of the present utility model.

[0053] refer to Figure 1 and Figure 2 The utility model provides a glass slide plate for staining and sealing microscope scanning, including a frame 1 and a clamping structure 2. The frame 1 includes an upper support plate 11 and a pair of side support plates 12. A row of placement positions 10 are arranged on the upper support plate 11. The placement positions 10 are suitable for placing glass slides 7. A picking space is provided on the placement positions 10. A pair of side support plates 12 are arranged at both ends of the upper support plate 11. The frame 1 is a frameless suspended structure; the clamping structure 2 is arranged on the upper support plate 11 and is suitable for clamping the glass slide 7 along the length direction, thickness direction or width direction of the placement position 10. The label-taking end of the glass slide 7 is the clamping part 71, and the other end of the glass slide 7 is the cell sample part 72.

[0054] In this embodiment, the label holding end of the glass slide 7 is the clamping part 71, and the other end of the glass slide 7 is the cell sample part 72. It is a frameless suspended structure, which makes it convenient to insert the sample part of the glass slide 7 into the reagent cylinder to achieve immersion staining. When moving back and forth between various reagent cylinders, less liquid is carried, which reduces cross-contamination of test liquids between reagent cylinders and reduces cleaning time. At the same time, it is convenient to operate directly on the cell part when dripping glue and sealing, without avoiding the frame of the glass slide plate. The entire process of staining, sealing, drying, scanning, etc. can be completed on a glass slide plate. The glass slide does not move on the glass slide 7 plate throughout the process, and there is no need to transfer the glass slide 7 additionally, saving time and effort.

[0055] Specifically, the present application provides a new type of glass slide plate that can achieve immersion staining, less liquid, easy and comfortable to take, and can realize the integrated whole process operation of staining, sealing and scanning. The glass slide does not move on the glass slide plate throughout the whole process, and there is no need to transfer it, which is convenient and time-saving, and can be used with both manual and fully automated equipment. A plurality of through grooves 110 are provided on the upper support plate 11. The clamping part 71 of the glass slide 7 is suitable for inserting into the through groove 110 along the length direction of the placement position 10. An upper notch 111 is provided on the top of the through groove 110. The upper notch 111 exposes the upper surface of the clamping part 71 of the glass slide 7, so that the label barcode of the glass slide 7 is exposed for easy scanning by a barcode camera. The clamping structure 2 is provided on both sides of the width direction of the upper notch 111 and is relatively located above the clamping part 71 of the glass slide 7 to prevent the glass slide 7 from falling. The whole process of staining, sealing, drying, scanning, etc. can be completed on the glass slide plate without the need for additional transfer of the glass slide 7, saving time and effort. The operator can take and put the glass slides comfortably without scratching the cells on the glass slides or the cover glass that has just been sealed with glue. It is also convenient for scanning between the glass slides directly after focusing during microscope scanning, without the need to avoid or refocus at a long distance, saving scanning time and achieving rapid scanning of multiple glass slides. The glass slides include glass slides and cover glass plates, and the cover glass plates are suitable for covering the glass slides. A lower notch 112 is also provided at the bottom of the through groove 110, and the lower notch 112 exposes the lower surface of the clamping portion 71 of the glass slide 7. One end of the glass slide 7 is fixedly mounted in the through groove 110 of the frame 1 and covers at least part of the upper notch 111 and the lower notch 112, so that the upper surface and the lower surface of one end of the glass slide 7 are exposed, and the outer sides of the upper notch 111 and the lower notch 112 form a picking space. The upper support plate 11 is provided with an upper notch 111 and a lower notch 112, so that the upper and lower surfaces of the clamping parts of the glass slide 7 are exposed through the upper notch 111 and the lower notch 112, making it easy to pinch the clamping parts of the glass slide 7 up and down to insert or push the glass slide 7 into or out of the through slot 110. The frame 1 is provided with a take-out space at one end of the placement position 10 in the longitudinal direction, so that the glass slide 7 can be easily and quickly taken out from the take-out space.

[0056] It is worth noting that at least one end of the frame 1 in the length direction of the placement position 10 is open, so that one end of the glass slide 7 is fixedly mounted on the frame 1 and a picking space is formed outside one end of the glass slide 7, and the other end of the glass slide 7 is suspended or fixed. The frame 1 is open at one end in the length direction of the placement position 10, that is, the frame 1 is suspended. The frame 1 is only provided with an upper support plate 11 and a side support plate 12. The side of the frame 1 away from the upper support plate 11 is open. The clamping portion 71 of the glass slide 7 is fixedly mounted on the frame 1 through the clamping structure 2, and the end of the glass slide 7 away from the clamping portion 71 is suspended. The end of the glass slide 7 away from the clamping portion 71 is suspended, which facilitates the insertion of the cell part of the glass slide 7 into the liquid in the staining tank. In this way, only the glass slide 7 is stained with liquid, and the frame 1 and the gap are not stained with liquid, thereby avoiding the reagent from being carried to the next tank of reagent and contaminating and diluting the next tank of reagent. The side support plates 12 are further provided with lifting rods 121 on both sides of the placement position 10 in the width direction. The lifting rods 121 are used to lift the glass slide 7 when inserting it into the staining tank. The lifting rods 121 are round rods that facilitate the glass slide to slide into the support positioning groove without getting stuck, facilitate the automatic hook lifting, and reduce friction resistance during the sliding process. The side support plates 12 on both sides act as a support frame.

[0057] Further, refer to Figures 2 to 4 The clamping structure 2 includes a plurality of upper stop cards 21 and a plurality of elastic pressing members 22 arranged at intervals. A pair of upper stop cards 21 are arranged at intervals at the top of the through groove 110. The elastic pressing members 22 are arranged below the upper stop cards 21 and are suitable for clamping the clamping portion 71 of the glass slide 7 along the thickness direction of the placement position 10.

[0058] Specifically, a pair of upper retaining clips 21 are spaced apart at the top of the through-slot 110, with an upper notch 111 defined between the pair of upper retaining clips 21. A through-slot 110 is defined between the upper retaining clips 21 and the bottom of the placement position 10. An elastic pressure member 22 is disposed at the top inner side of the through-slot 110 and is adapted to clamp the clamping portion 71 of the glass slide 7 along the thickness direction of the placement position 10. In this embodiment, the label end of the glass slide 7 serves as the clamping portion 71 of the glass slide 7. The through-slot 110 extends through the length of the upper support plate 11, and the glass slide 7 is adapted to pass through the through-slot 110. The through-slot 110 is continuous along the length of the placement position 10, allowing the glass slide 7 to slide through the through-slot 110 and be pressed into the through-slot 110 by the elastic pressure member 22. Insert the glass slide 7 from the through slot 110, and use the elastic pressure member 22 of the upper block 21 to press the clamping portion 71 of the glass slide 7 to clamp the glass slide 7. The elastic pressure member 22 only presses the edges of the glass slide 7, so that the sample on the glass slide 7 will not be scratched during insertion. In addition, after the stained cover slide is scanned and read, the sample slide needs to be stored and removed to prevent the elastic pressure member 22 from scraping off the cover slide 7 after the glue is applied. The covered glass slide 7 is removed from the glass slide plate in the following way: use two fingers to push the clamping portion 71 of the glass slide 7 horizontally through the lower notch 112 of the glass slide plate. At this time, at least one side of the top of the glass slide 7 is out of the through slot 110, and the glass slide 7 can be removed by lifting it upwards without any obstruction, and the glass slide plate can be removed.

[0059] Preferably, the lower notch 112 is U-shaped, and the upper stopper 21 on at least one side of the upper notch 111 does not extend beyond the bottom of the lower notch 112. This allows the slide 7 to be pushed upward on one or both sides of the slide 7, allowing for easy removal without scraping the cover glass where the glue has not yet dried on the slide. Specifically, there are two types of upper stoppers. The first type is when the upper stopper 21 on one side of the upper notch 111 does not extend beyond the bottom of the lower notch 112, while the other side extends beyond the bottom of the lower notch 112. This means that one side of the upper stopper 21 is a long stop, while the other side is a short stop. The second type is when the upper stopper 21 on both sides of the upper notch 111 does not extend beyond the bottom of the lower notch 112. This means that both sides of the upper stopper 21 are short stops. The first method involves pinching the two ends of the slide 7 in the longitudinal direction with two fingers and sliding the gripping portion 71 of the slide 7 away from the lower notch 112 of the slide plate. At this point, one side of the slide 7 remains within the long stop, while the other side is free from the short stop. The operator then tilts the sample upward from the short stop 311 to remove the slide 7. The second method involves sliding the gripping portion 71 of the slide 7 across the lower notch 112 of the slide plate with two fingers. At this point, the slide 7 is free from the left and right short stops, and thus from the slide plate, allowing it to be lifted upward to be removed without any obstruction. The first method provides a larger gripping surface and a more secure hold, while the second method provides greater convenience. The purpose of doing this is: because the glue on the glass slide that has just been sealed with glue has not dried yet, the cover glass is easy to slide. At the same time, the standard cover glass is 24 mm wide and the sample slide is 25 mm wide. The cover glass is only a little distance away from the edge of the glass slide. When the glass slide is pulled out from the through groove 110, it is easy to scratch the cover glass. Therefore, the glass slide needs to be taken out without obstruction or scratching. The above structure is designed for this purpose.

[0060] It is worth noting that the shape of the lower notch 112 is U-shaped. In another embodiment, the shape of the through groove 110 can also be rectangular. The lower notch 112 of the present application can also be of other irregular shapes, as long as it is exposed below the clamping portion 71 of the glass slide 7, so that the fingers can touch the lower surface of the glass slide 7 during operation. At the same time, the clamping structure 2 clamps one end of the label end of the glass slide 7, and the clamping structure 2 only occupies the portion of the upper surface of the clamping portion 71 of the glass slide 7, that is, the upper notch 111 is provided between the upper stopper, and the upper stopper 21 does not block the clamping portion 71. At the same time, it is convenient for the glue needle of the automated equipment to slide across the upper surface of the glass slide 7 without having to rise to avoid the upper stopper, and it is convenient for the glass slide 7 to be pulled out without blocking the glass slide 7. The elastic holding members 22 are clamped on the left and right upper edges of the frame 1, that is, the elastic holding members 22 are pressed on the two side bevels of the glass slide 7, and the glass slide 7 is elastically positioned without gaps in the left and right directions and up and down directions. Preferably, the elastic holding members 22 are set at the four corners of the upper block 21, and there are 2 to 3 elastic holding members 22 on each of the left and right sides to prevent the glass slide 7 from tilting left and right and warping up and down. When the glass slide is inserted into the microscope scanning platform, the elastic holding members 22 are pressed on the end of the glass slide with the clamping portion 71. In this way, even if the glass slide is slightly deformed, the glass slide 7 can form a flat scanning surface. It is worth noting that in this embodiment, the frame 1 is open at one end in the length direction of the placement position 10. In another embodiment, the frame 1 is open at both ends in the length direction of the placement position 10, so that the clamping structure 2 clamps the middle part of the glass slide 7, and both ends of the length direction of the glass slide 7 are suspended.

[0061] Further, refer to Figure 5 and Figure 6 The clamping structure 2 includes an elastic upper stopper 31 and a long groove upper stopper 32, which are respectively arranged on both sides of the width direction of the upper notch 111 and are relatively located above the clamping part 71 of the glass slide 7; the elastic upper stopper 31 is elastically connected to the end of the upper support plate 11, and a buffer bent hole 33 is also provided at the connection between the elastic upper stopper 31 and the upper support plate 11, so that the elastic upper stopper 31 is suitable for elastically abutting the upper surface of the clamping part 71 of the glass slide 7, and a card groove 321 is provided at the bottom of the long groove upper stopper 32, and the card groove 321 is communicated with the through groove 110; when the glass slide 7 is pushed into the through groove 110, the elastic upper stopper 31 elastically squeezes the glass slide 7 and drives the glass slide 7 into the card groove 321 of the long groove upper stopper 32.

[0062] Specifically, when the operator inserts the glass slide 7 into the through slot 110, the front end of the glass slide 7 presses against the elastic upper stopper 31, which pushes the glass slide 7 into the slot 321 of the long slot upper stopper 32. The glass slide 7 is then abutted between the elastic upper stopper 31 and the long slot upper stopper 32. Preferably, a short stopper 311 is provided on the side of the elastic upper stopper 31 near the long slot upper stopper 32. The short stopper 311 does not extend beyond the bottom of the lower notch 112. This ensures that when the glass slide is removed, the upper portion of the glass slide is free of the short stopper when the slide is pushed forward to the bottom of the lower notch, allowing the operator to remove the glass slide upward. The short stopper 311 is adapted to abut the upper surface of the glass slide 7, preventing the glass slide 7 from shaking up and down. When the glass slide 7 abuts between the elastic upper stop 31 and the long slot upper stop 32, the elastic upper stop 31 abuts the end of the glass slide 7 along the width of the placement position 10, while the short stop 311 abuts the upper surface of the glass slide 7 along the thickness of the placement position 10, thereby clamping the glass slide 7 to the slide plate. It is worth noting that the short stop 311 does not extend beyond the bottom of the lower notch 112. This facilitates the removal of the glass slide 7 from the short stop 311 after it reaches the bottom of the lower notch 112. This facilitates upward removal of the glass slide. The glue on the glass slide has not yet dried, making it easy for the cover glass to slide. Furthermore, since a standard cover glass is 24 mm wide and a specimen slide is 25 mm wide, the cover glass is only slightly away from the edge of the slide. Therefore, the slide needs to be removed without any scratches or interference. The above structure is designed for this purpose.

[0063] In a modified embodiment, reference Figure 7 and Figure 8 The clamping structure 2 includes an upper pressing plate 41, a first elastic member 42 and a baffle 43. The upper pressing plate 41 is arranged on both sides of the placement position 10 in the width direction. The upper pressing plate 41 includes a pressing portion 411 and an elastic portion 412. The pressing portion 411 is suitable for clamping the glass slide 7 along the thickness direction of the placement position 10. A movable groove 44 is provided at the bottom of the through groove 110. The elastic portion 412 is suitable for extending into the movable groove 44. A snap groove 413 is provided on the side of the elastic portion 412 away from the pressing portion 411. The snap groove 413 is suitable for installing the baffle 43. The first elastic member 42 elastically connects the baffle 43 and the bottom of the upper support plate 11, so that the pressing portion 411 of the upper pressing plate 41 and the upper support plate 11 clamp one end of the glass slide 7 along the thickness direction of the placement position 10 under the action of the first elastic member 42.

[0064] Further, refer to Figure 9 and Figure 10The clamping structure 2 includes a spring clip 51 and a fixing column 52. A through groove 110 is provided on the upper support plate 11. A contact surface 53 is provided at the end of the through groove 110. The contact surface 53 is suitable for contacting the end of the glass slide 7. The spring clips 51 are arranged at intervals at both ends of the through groove 110 in the width direction and are suitable for clamping both sides of the glass slide 7 in the width direction. A fixing groove 55 seat 54 is provided on the upper surface of the upper support plate 11. The spring clip 51 is installed on the two side walls of the fixing groove 55 seat 54 through the fixing column 52, so that the spring clip 51 is suitable for clamping the glass slide 7 along the thickness direction of the placement position 10.

[0065] Specifically, refer to Figure 7 and Figure 8 The clamping structure 2 includes a spring clip 51 and a fixing post 52. The spring clip 51 is disposed within the fixing groove 55 seat 54 and is adapted to clamp the upper surfaces of both ends of the glass slide 7 in the width direction. An abutting surface 53 is provided at the end of the placement position 10, and the abutting surface 53 is adapted to abut against one end of the glass slide 7. That is, the through groove 110 does not pass through both ends of the placement position 10 in the length direction. The spring clip 51 is mounted on both side walls of the fixing groove 55 seat 54 via the fixing post 52. That is, the opposite side walls of the fixing groove 55 seat 54 are connected by the fixing post 52 at both ends of the spring clip 51, so that the spring clip 51 is adapted to clamp one end of the glass slide 7 along the thickness direction of the placement position 10. The spring clip 51 is lifted upward, one end of the glass slide 7 is placed above the through groove 110, and then the spring clip 51 is lowered to clamp the glass slide 7. It is worth noting that a fixing groove 55 is further provided on the upper support plate 11 between adjacent placement positions 10 , and the side of the spring clip 51 away from the fixing column 52 is suitable for being snapped and fixed in the fixing groove 55 to prevent the spring clip 51 from shifting or shaking.

[0066] Further, refer to Figure 11 and Figure 12 The clamping structure 2 includes an elastic rod 61 and a second elastic member 62. A through groove 110 is provided on the upper support plate 11. The end of the through groove 110 is provided with an abutting inclined surface 63. The abutting inclined surface 63 is suitable for clamping one end of the glass slide 7; the elastic rod 61 passes through the upper support plate 11 along the length direction of the placement position 10. The elastic rod 61 includes an elastic end 611 and a clamping end 612. A second elastic member 62 is provided between the elastic end 611 and the side of the upper support plate 11 away from the placement position 10. A barb 613 is provided on the clamping end 612. The barb 613 is suitable for clamping the other end of the glass slide 7, so that the abutting inclined surface 63 and the barb 613 of the elastic rod 61 clamp the glass slide 7 along the length direction of the placement position 10.

[0067] Specifically, the abutting bevel 63 is adapted to engage one end of the glass slide 7. Of course, the abutting bevel 63 may also have other shapes, such as an arc or an ellipse. The abutting bevel 63 may be configured according to the end surface of the glass slide 7, and this application does not provide further limitations. This abutting bevel 63 is similar to the abutting surface 53 in the previous embodiment, except that the abutting surface 53 in the previous embodiment does not need to provide vertical restraint and is vertically disposed. In contrast, in this embodiment, the abutting bevel 63 abuts against the upper surface of the glass slide 7, providing partial vertical restraint. The elastic rod 61 extends through the upper support plate 11 along the length of the placement position 10. The elastic rod 61 includes an elastic end 611 and a clamping end 612. A second elastic member 62 is provided between the elastic end 611 and the side of the upper support plate 11 away from the placement position 10. The clamping end 612 is provided with a barb 613. The barb 613 is suitable for clamping the other end of the glass slide 7, so that the abutting inclined surface 63 of the upper support plate 11 and the barb 613 of the elastic rod 61 clamp the glass slide 7 along the length of the placement position 10. Specifically, the elastic end 611 of the elastic rod 61 is provided with the second elastic member 62, so that the elastic rod 61 can be pulled along the length of the placement position 10, the clamping end 612 of the elastic rod 61 is away from the upper support plate 11, and the glass slide 7 is then placed in the placement position 10. When the elastic rod 61 is released, the second elastic member 62 drives the elastic rod 61 to move in the opposite direction and clamp the glass slide 7 between the upper support plate 11 and the clamping end 612. At the same time, the clamping end 612 is provided with a barb 613, and the upper support plate 11 abuts against the inclined surface 63, allowing the upper support plate 11 and the clamping end 612 to better clamp the glass slide 7, providing restraint in both the length and thickness directions of the glass slide 7. The restraint in the width direction of the glass slide 7 is provided by the upper support plate 11 between adjacent placement locations 10. It is worth noting that the clamping structure 2 in the above embodiment can also be repositioned so that the clamping structure 2 can clamp the glass slide 7 in either the width or length direction of the placement locations 10.

[0068] It should be noted that the above embodiments can be freely combined as needed. The above are only preferred embodiments of the present invention. It should be noted that those skilled in the art can make several improvements and modifications without departing from the principles of the present invention, and such improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A glass slide for staining and sealing microscope scanning, characterized in that: include: The frame comprises an upper support plate and a pair of side support plates, wherein a row of placement positions are provided on the upper support plate, each of which is suitable for placing a glass slide and has a take-out space, and a pair of side support plates are provided at both ends of the upper support plate. The frame is a frameless suspended structure; The clamping structure is arranged on the upper support plate and is suitable for clamping the glass slide along the length direction, thickness direction or width direction of the placement position, the label holding end of the glass slide is the clamping part, and the other end of the glass slide is the cell sample part.

2. A glass slide for staining and sealing microscope scanning according to claim 1, characterized in that: The upper support plate is provided with a plurality of through grooves, the clamping portion of the glass slide is suitable for being inserted into the through grooves along the length direction of the placement position, the top of the through groove is provided with an upper notch, the upper notch exposes the upper surface of the clamping portion of the glass slide, and the clamping structure is provided on both sides of the upper notch in the width direction and is relatively located above the clamping portion of the glass slide; A lower notch is further provided at the bottom of the through groove, wherein the lower notch exposes the lower surface of the clamping portion of the glass slide, and the upper notch and the lower notch form the taking space.

3. A glass slide for staining and sealing microscope scanning according to claim 2, characterized in that: The clamping structure includes a plurality of upper stop cards and a plurality of elastic pressing members arranged at intervals. A pair of the upper stop cards are arranged at intervals at the top of the through groove. The elastic pressing members are arranged below the upper stop cards and are suitable for clamping the clamping part of the glass slide along the thickness direction of the placement position.

4. A glass slide for staining and sealing microscope scanning according to claim 3, characterized in that: The lower notch is U-shaped, and the upper stopper on at least one side of the upper notch does not exceed the bottom of the lower notch, so that after pushing the glass slide, one side or both sides of the glass slide can move upward away from the upper stopper, making it convenient to remove the glass slide without scratching the cover glass on the glass slide that has just been sealed with glue and the glue that has not yet dried.

5. The glass slide plate for staining and sealing microscope scanning according to claim 2, characterized in that: The clamping structure includes an elastic upper stopper and a long slot upper stopper, wherein the elastic upper stopper and the long slot upper stopper are respectively arranged on both sides of the width direction of the upper notch and are relatively located above the clamping portion of the glass slide; The elastic upper stopper is elastically connected to the end of the upper support plate, and a buffer bent hole is further provided at the connection between the elastic upper stopper and the upper support plate, so that the elastic upper stopper is suitable for elastically abutting the upper surface of the clamping part of the glass slide, and a card slot is provided at the bottom of the long slot upper stopper, and the card slot is connected to the through slot; When the glass slide is pushed into the through slot, the elastic upper stopper elastically presses the glass slide and drives the glass slide and the long slot upper stopper into the slot.

6. The glass slide plate for staining and sealing microscope scanning according to claim 5, characterized in that: A short stop is provided on one side of the elastic upper stop close to the long slot upper stop, and the short stop does not exceed the bottom of the lower notch. The purpose is that when the glass slide is taken out, the upper part of the glass slide is separated from the short stop when the glass slide is pushed forward to the bottom of the lower notch, and the operator can take the glass slide out upward.

7. The glass slide plate for staining and sealing microscope scanning according to claim 2, characterized in that: The clamping structure includes an upper pressing plate, a first elastic member and a baffle, the upper pressing plate is arranged on both sides of the placement position in the width direction, the upper pressing plate includes a pressing portion and an elastic portion, the pressing portion is suitable for clamping the glass slide along the thickness direction of the placement position, the upper support plate is provided with a movable groove, the elastic portion is suitable for extending into the movable groove, and the side of the elastic portion away from the pressing portion is provided with a snap groove, the snap groove is suitable for installing the baffle, The first elastic member elastically connects the baffle and the bottom of the upper support plate, so that the pressing portion of the upper pressing plate and the upper support plate clamp one end of the glass slide along the thickness direction of the placement position under the action of the first elastic member.

8. The glass slide plate for staining and sealing microscope scanning according to claim 2, characterized in that: The clamping structure includes a spring clip and a fixing column. The upper support plate is provided with the through groove, and the end of the through groove is provided with an abutting surface, which is suitable for abutting with the end of the glass slide. The spring clips are arranged at intervals at both ends of the through groove in the width direction and are suitable for clamping both sides of the glass slide in the width direction. The upper surface of the upper support plate is provided with a fixing groove seat, and the spring clip is installed on the two side walls of the fixing groove seat through the fixing column, so that the spring clip is suitable for clamping the glass slide along the thickness direction of the placement position.

9. The glass slide plate for staining and sealing microscope scanning according to claim 2, characterized in that: The clamping structure includes an elastic rod and a second elastic member, the through groove is provided on the upper support plate, the end of the through groove is provided with an abutting inclined surface, and the abutting inclined surface is suitable for clamping one end of the glass slide; the elastic rod passes through the upper support plate along the length direction of the placement position, and the elastic rod includes an elastic end and a clamping end, and the second elastic member is provided between the elastic end and the side of the upper support plate away from the placement position, and the clamping end is provided with a barb, and the barb is suitable for clamping the other end of the glass slide, so that the abutting inclined surface and the barb of the elastic rod clamp the glass slide along the length direction of the placement position.