Transportation and storage box for sampling tissues for single cell sequencing

Abstract

The utility model provides a transportation and storage box for sampling tissues for single cell sequencing, which comprises a box body for transporting single cell sequencing sample tissues, a telescopic handle arranged on one side of the box body, bottom blocks attached and connected to two ends of the lower surface of the box body, a fixed shell fixedly mounted on one side of each bottom block, and an expansion slot arranged on the other side of the box body, a moving assembly is fixedly installed at one end of the inner wall of the upper surface of the expansion groove, the other two sides of the moving assembly are located in the fixing shell, and linkage holes are formed in the two sides of the inner wall of the expansion groove. Buffering and damping effects can be achieved through polyethylene foam and silicone rubber bonded in a first empty groove of a bottom block, damage of vibration to the sampling tissue in the transportation process is reduced, when the sampling tissue is transported to a designated place, the transportation efficiency of the box body can be improved through a moving assembly, the sampling tissue can be conveniently transported among different places, the transportation efficiency is improved, and the transportation cost is reduced. And the conditions of difficult movement and physical power consumption during carrying are reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of single-cell sequencing transport boxes, and in particular to a transport and storage box for sampling tissues used for single-cell sequencing. Background Art

[0002] The single-cell sequencing process includes single-cell suspension preparation, single cell capture, DNA / RNA amplification, library construction, and data analysis. To prepare a single-cell suspension, you first need to sample the target tissue and transport it to the laboratory where the sequencing will be performed to prepare the suspension. Since the sampling location and the laboratory are often not in the same location, or even in the same city, the tissue samples need to be transported to the laboratory after sampling. During this process, a storage box is needed to store the tissue samples. To ensure cell activity, they need to be stored at low temperatures in an ice bath. The tissue transport storage box used for single-cell sequencing is a device specifically designed for the safe and efficient transportation and storage of single-cell sequencing sampled tissues.

[0003] For example, the patent with national authorized patent announcement number CN221139152U discloses a transportation and storage box for sampling tissue for single-cell sequencing, including a box body, the upper end of the box body extends downward and has an inner cavity, the upper end of the box body is connected to a sealed box cover by a snap, the inner cavity is divided into a storage cavity located above and a mechanism cavity located below by a fixed partition plate, the storage cavity is matched with a storage tank, a refrigeration box is provided in the mechanism cavity, the refrigeration box is provided with a refrigeration mechanism, a water inlet and a water outlet are provided at the bottom of the storage tank, the water outlet is connected to the refrigeration box through a first water pipe, the bottom of the refrigeration box is connected to the water inlet through a second water pipe, the second water pipe is provided with a water pump, a battery compartment is also provided in the mechanism cavity, the battery compartment is electrically connected to the water pump and the refrigeration mechanism through a switch, the switch is provided on the outer wall of the box body, and a charging port electrically connected to the battery compartment is also provided on the outer wall of the box body. The utility model can maintain a low-temperature environment for a long time to store samples, which is convenient for long-distance transportation of samples.

[0004] However, the above-mentioned transport and storage boxes for sampling tissues used for single-cell sequencing have a relatively bulky overall structure. In large laboratories, the sampling tissues may need to be transported from one area to another, which makes it difficult to carry them during movement and easily consumes physical energy. In large laboratories, aisles and elevators are common transportation channels. Storage boxes that lack mobile structures are more difficult to move in these places and may require the collaboration of multiple people to carry them through. This not only increases labor costs, but may also affect the laboratory's work efficiency. Utility Model Content

[0005] The utility model aims to solve the problems raised in the background technology and provides a transport and storage box for sampled tissues used for single-cell sequencing.

[0006] The specific technical solutions are as follows:

[0007] A transport and storage box for sampling tissue for single-cell sequencing comprises: a box body for transporting single-cell sequencing sample tissue, a telescopic handle provided on one side of the box body, bottom blocks fittedly connected at both ends of the lower surface of the box body, a fixed shell fixedly mounted on one side of the bottom block, an expansion slot provided on the other side of the box body, a movable assembly fixedly mounted on one end of the inner wall of the upper surface of the expansion slot, the other two sides of the movable assembly being located within the fixed shell, linkage holes provided on both sides of the inner wall of the expansion slot, a notch provided at one end of the linkage hole, a box cover provided at one end of the upper surface of the box body, and the other end of the box cover mounted in the notch.

[0008] As a preferred solution of the present invention, a first empty groove is provided at one end of the lower surface of the bottom block, polyethylene foam is bonded and installed in the first empty groove, silicone rubber is bonded and installed at one end of the lower surface of the polyethylene foam, and a second empty groove is provided at one end of one of the two groups of bottom blocks, a fastening bolt is inserted in the second empty groove, and the other end of the fastening bolt is inserted into the other group of bottom blocks.

[0009] As a preferred solution of the present invention, the inner wall of the box is coated with a nano-silver coating, and a sliding hole is provided on one side of the inner wall of the fixed shell.

[0010] As a preferred solution of the present invention, the movable assembly includes a first mounting block and a second mounting block, one end of the first mounting block and the second mounting block are both connected with a fixing bolt, the other end of the fixing bolt is connected to one end of the expansion slot, the first mounting block and the second mounting block are installed in an upper and lower position, and one end of the upper surface of the first mounting block and the second mounting block are both provided with a threaded hole.

[0011] As a preferred solution of the present invention, a lifting screw is threadedly installed in the threaded hole, a handle is provided at one end of the upper surface of the lifting screw, one end of the lifting screw is threadedly connected to a linkage plate, and both sides of the linkage plate are fixedly connected to connecting frames.

[0012] As a preferred solution of the present invention, a slider is fixedly installed on one side of the connecting frame, the slider is slidably installed in the sliding hole, and one end of the lower surface of the connecting frame is rotatably connected to a movable caster.

[0013] The utility model has the following beneficial effects:

[0014] 1. The transport and storage box for sampling tissues for single-cell sequencing provided by the present invention has a box body, an expansion slot, a mobile component, and a bottom block. When transporting the box body, the sampling tissue is placed in the box body. The nano-silver coating applied to the box body has an antibacterial effect and can prevent bacteria from growing, thereby providing a relatively sterile storage environment for the sampling tissue. The polyethylene foam and silicone rubber bonded in the first empty slot of the bottom block can then play a buffering and shock-absorbing role, thereby reducing the damage to the sampling tissue caused by vibration during transportation. When transporting to a designated location, the mobile component can speed up the transportation efficiency of the box body, facilitate the transportation of sampling tissues between different locations, improve transportation efficiency, reduce the difficulty of movement, and reduce the physical effort of carrying. In addition, the design of the expansion slot and the sliding hole facilitates the disassembly and assembly of the mobile component by the staff, thereby improving convenience during use.

[0015] 2. The transport and storage box for sampling tissue for single-cell sequencing provided by the present invention is fixed in the expansion slot by fixing bolts through the first mounting block and the second mounting block. The upper and lower mounting method can increase stability. Then, by rotating the lifting screw threadedly connected in the first mounting block and the second mounting block, the linkage plate threadedly connected at one end of the lifting screw is threadedly driven and lifted, and the connecting frames fixedly connected on both sides thereof will also be lifted and lowered. The slider fixedly installed on one side of the connecting frame slides in the sliding hole on the inner wall of the fixed shell to ensure the stability and directionality of the connecting frame during the lifting process. When the linkage plate is lowered, the movable caster connected to the lower surface of the connecting frame at one end thereof is rotatable and contacts the ground. Then, the transport and storage box can be conveniently moved using the movable caster and the telescopic handle. When moving, it does not require multiple people to carry it through, reducing labor costs and avoiding reducing experimental efficiency. When it is not necessary to move, the lifting screw is rotated in the opposite direction to make the linkage plate rise, the movable caster leaves the ground, and the box can be stably placed. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 Schematic diagram of the overall structure of the transport and storage box for sampling tissue for single-cell sequencing provided by the embodiment of the utility model Figure 1 ;

[0017] Figure 2 Schematic diagram of the structure of the box expansion slot provided by the embodiment of the utility model Figure 2 ;

[0018] Figure 3 Schematic diagram of the structure of the bottom block of the box provided in the embodiment of the utility model Figure 3 ;

[0019] Figure 4 Schematic diagram of the structure of the bottom block and the fixed shell provided in the embodiment of the utility model Figure 4 ;

[0020] Figure 5Schematic diagram of the structure of the mobile assembly provided in the embodiment of the utility model Figure 5 ;

[0021] Figure 6 A schematic diagram of the structure of the lifting of the mobile assembly provided in an embodiment of the utility model;

[0022] Figure 7 for Figure 6 Illustration of the movable castors in the center view.

[0023] In the attached figure:

[0024] 1. Box body; 101. Telescopic handle; 102. Box cover; 103. Linkage hole; 104. Expansion slot; 2. Bottom block; 201. Fastening bolt; 202. Polyethylene foam; 203. Silicone rubber; 204. Fixed shell; 205. Slide hole; 3. Moving assembly; 301. First mounting block; 302. Second mounting block; 303. Fixing bolt; 304. Lifting screw; 305. Linkage plate; 306. Slider; 307. Connecting frame; 308. Movable casters. DETAILED DESCRIPTION

[0025] The technical solution of the present invention will be further described below with reference to the accompanying drawings and through specific implementation methods.

[0026] Among them, the drawings are only used for illustrative purposes and represent only schematic diagrams rather than actual pictures, and should not be understood as limiting this patent; in order to better illustrate the embodiments of the utility model, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of the actual product; for those skilled in the art, it is understandable that some well-known structures and their descriptions in the drawings may be omitted.

[0027] The same or similar numbers in the drawings of the embodiments of the present invention correspond to the same or similar parts; in the description of the present invention, it should be understood that if the terms "upper", "lower", "left", "right", "inside", "outside" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, they are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and cannot be understood as limiting this patent. For ordinary technicians in this field, the specific meanings of the above terms can be understood according to specific circumstances.

[0028] In the description of this utility model, unless otherwise expressly specified or limited, when the term "connection" or the like appears to indicate a connection relationship between components, such term should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be internal communication between two components or an interaction relationship between two components. For those skilled in the art, the specific meanings of the above terms in this utility model can be understood according to the specific circumstances.

[0029] Example 1

[0030] The transport storage box for sampling tissue for single-cell sequencing provided in this embodiment is as follows: Figure 1-Figure 7 As shown, the box 1 comprises: a box 1 for transporting single-cell sequencing sample tissues, with a telescopic handle 101 provided on one side of the box 1. A bottom block 2 is attached to each end of the bottom surface of the box 1. A fixed shell 204 is fixedly mounted on each side of the bottom block 2. An expansion slot 104 is provided on the other side of the box 1. A mobile assembly 3 is fixedly mounted on one end of the inner wall of the upper surface of the expansion slot 104. The other two sides of the mobile assembly 3 are located within the fixed shell 204. Linkage holes 103 are provided on both sides of the inner wall of the expansion slot 104. One end of the linkage hole 103 has a notch. A box cover 102 is provided on one end of the upper surface of the box 1, and the other end of the box cover 102 is mounted within the notch. A first slot is provided on one end of the lower surface of the bottom block 2. Polyethylene foam 202 is bonded and mounted in the first slot. Silicone rubber 203 is bonded and mounted on one end of the lower surface of the polyethylene foam 202. A second slot is provided on one end of one of the two sets of bottom blocks 2. A fastening bolt 201 is inserted into the second slot. The other end of the fastening bolt 201 is inserted into the other set of bottom blocks 2. The inner wall of the box body 1 is coated with a nano silver coating, and a sliding hole 205 is provided on one side of the inner wall of the fixed shell 204.

[0031] Through the design of the box body 1, the expansion slot 104, the mobile component 3, and the bottom block 2, when transporting the box body 1, by placing the sampled tissue in the box body 1, the nano silver coating applied in the box body 1 has an antibacterial effect, which can prevent bacteria from growing and provide a relatively sterile storage environment for the sampled tissue. Then, the polyethylene foam 202 and the silicone rubber 203 bonded in the first empty slot of the bottom block 2 can play a buffering and shock-absorbing role, reducing the damage to the sampled tissue caused by vibration during transportation. When transporting to the designated location, the mobile component 3 can speed up the transportation efficiency of the box body 1, facilitate the transportation of sampled tissues between different locations, improve transportation efficiency, reduce the difficulty of movement, and reduce the physical effort of carrying. In addition, through the design of the expansion slot 104 and the sliding hole 205, it is convenient for staff to disassemble and assemble the mobile component 3, which can improve convenience during use.

[0032] The telescopic handle 101 is a common structure currently and will not be described in detail here.

[0033] Example 2

[0034] The transport storage box for sampling tissue for single-cell sequencing provided in this embodiment is as follows: Figure 6-Figure 7 As shown, the movable assembly 3 includes a first mounting block 301 and a second mounting block 302. A fixing bolt 303 is inserted into one end of each of the first and second mounting blocks 301, 302. The other end of the fixing bolt 303 is inserted into one end of the expansion slot 104. The first and second mounting blocks 301, 302 are mounted one above the other, and each has a threaded hole at one end of its top surface. A lifting screw 304 is threadedly mounted within the threaded hole. A handle is provided at one end of the lifting screw 304. A linkage plate 305 is threadedly connected to one end of the lifting screw 304. Connecting frames 307 are fixedly connected to both sides of the linkage plate 305. Sliders 306 are fixedly mounted on one side of the connecting frame 307. The sliders 306 are slidably mounted within the sliding holes 205. A movable caster 308 is rotatably connected to one end of the bottom surface of the connecting frame 307.

[0035] The first mounting block 301 and the second mounting block 302 are both fixed in the expansion slot 104 by fixing bolts 303. The up-down mounting method can increase stability. Then, by rotating the lifting screw 304 threadedly connected in the first mounting block 301 and the second mounting block 302, the linkage plate 305 threadedly connected at one end of the lifting screw 304 is threadedly driven and lifted, and the connecting frame 307 fixedly connected on both sides thereof will also rise and fall accordingly. The slider 306 fixedly installed on one side of the connecting frame 307 slides in the sliding hole 205 on the inner wall of the fixed shell 204. The movable caster 308 is rotated and connected to one end of the lower surface of the connecting frame 307 to contact the ground. The movable caster 308 and the telescopic handle 101 can then be used to conveniently move the storage box for transportation. When moving, it does not require multiple people to carry it through, reducing labor costs and avoiding reducing experimental efficiency. When it is not necessary to move, the lifting screw 304 is rotated in the opposite direction to make the connecting plate 305 rise, the movable caster 308 leaves the ground, and the box body 1 can be stably placed.

[0036] In summary, the transport and storage box for sampling tissue for single-cell sequencing provided in this embodiment has the following advantages: after the sampling tissue for single-cell sequencing is moved to the designated location through the transport and storage box, the overall movement can be completed without the cooperation of multiple people, and one person can easily carry it, which greatly reduces the physical exertion during transportation, thereby saving labor costs and reducing the time wasted due to transportation difficulties, so that the sampling tissue can be transported more quickly and safely between different areas of the laboratory, which can effectively improve the work efficiency of the laboratory.

[0037] When in use, place the box body 1 on the two groups of bottom blocks 2, and push the bottom block 2 after placement so that the fixed shell 204 fixedly installed at one end of the bottom block 2 is tightly fitted to one side of the box body 1. Then, use a tool to rotate the fastening bolts 201 connected between the two groups of bottom blocks 2 so that the two groups of fixed shells 204 are tightly fitted to both sides of the box body 1 through the fastening bolts 201 tightened at one end of the bottom block 2. Then, place both sides of the mobile component 3 in the fixed shell 204, and ensure stability during installation through the cooperation of the slider 306 and the slide hole 205. The first mounting block 301 and the second mounting block 302 are fitted to one end of the inner wall of the expansion slot 104 and fixed by a fixing bolt 303. When the storage box needs to be moved and transported, the handle on the lifting screw 304 can be rotated to make the lifting screw 304 drive the linkage plate 305 to descend, thereby driving the connecting frame 307 and the movable caster 308 to descend until the movable caster 308 touches the ground. After that, the box body 1 can be easily driven for transportation by the telescopic handle 101, which can facilitate the transportation of sample tissues for single-cell sequencing from one area to another.

[0038] The above are only preferred embodiments of the present invention and do not limit the implementation methods and protection scope of the present invention. Those skilled in the art should be aware that all solutions obtained by equivalent substitutions and obvious changes made using the description and illustrations of the present invention should be included in the protection scope of the present invention.

Claims

1. A transport and storage box for sampling tissue for single-cell sequencing, characterized in that: include: A box (1) for transporting single-cell sequencing sample tissues, wherein a telescopic handle (101) is provided on one side of the box (1), a bottom block (2) is fitted and connected at both ends of the lower surface of the box (1), a fixed shell (204) is fixedly installed on one side of the bottom block (2), an expansion slot (104) is provided on the other side of the box (1), a moving component (3) is fixedly installed on one end of the inner wall of the upper surface of the expansion slot (104), and the other two sides of the moving component (3) are located in the fixed shell (204), linkage holes (103) are opened on both sides of the inner wall of the expansion slot (104), and a notch is provided at one end of the linkage hole (103), a box cover (102) is provided at one end of the upper surface of the box (1), and the other end of the box cover (102) is installed in the notch.

2. The transport and storage box for sampling tissue for single-cell sequencing according to claim 1, characterized in that: A first empty slot is provided at one end of the lower surface of the bottom block (2), polyethylene foam (202) is bonded and installed in the first empty slot, and silicone rubber (203) is bonded and installed at one end of the lower surface of the polyethylene foam (202). A second empty slot is provided at one end of one of the two groups of bottom blocks (2), a fastening bolt (201) is inserted into the second empty slot, and the other end of the fastening bolt (201) is inserted into the other group of bottom blocks (2).

3. The transport and storage box for sampling tissue for single-cell sequencing according to claim 1, characterized in that: The inner wall of the box body (1) is coated with a nano silver coating, and a sliding hole (205) is provided on one side of the inner wall of the fixed shell (204).

4. The transport and storage box for sampling tissue for single-cell sequencing according to claim 1, characterized in that: The moving assembly (3) comprises a first mounting block (301) and a second mounting block (302); one end of each of the first mounting block (301) and the second mounting block (302) is plugged with a fixing bolt (303); the other end of each of the fixing bolts (303) is plugged into one end of the expansion slot (104); the first mounting block (301) and the second mounting block (302) are installed in an upper and lower position, and one end of the upper surface of each of the first mounting block (301) and the second mounting block (302) is provided with a threaded hole.

5. The transport and storage box for sampling tissue for single-cell sequencing according to claim 4, characterized in that: A lifting screw (304) is threadedly installed in the threaded hole, a handle is provided on one end of the upper surface of the lifting screw (304), one end of the lifting screw (304) is threadedly connected to a linkage plate (305), and both sides of the linkage plate (305) are fixedly connected to a connecting frame (307).

6. The transport and storage box for sampling tissue for single-cell sequencing according to claim 5, characterized in that: A slider (306) is fixedly installed on one side of the connecting frame (307), and the slider (306) is slidably installed in the sliding hole (205). One end of the lower surface of the connecting frame (307) is rotatably connected to a movable caster (308).

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