Piston device convenient for uniformly shaking harvesting liquid in cell factory

By designing a piston device, the piston movement is controlled by using the driving motor and gear mechanism, the problem of difficult to shake the harvesting liquid in the ten-layer cell factory is solved, and the uniform mixing of the harvesting liquid is achieved, and the uniformity and efficiency of cell culture are improved.

CN223292563UActive Publication Date: 2025-09-02JIANGSU CONVAC BIO TECH CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202422462216.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-12
Publication Date
2025-09-02
Estimated Expiration
2034-10-12

AI Technical Summary

Technical Problem

In the prior art, the harvesting liquid of the ten-layer cell factory is difficult to shake evenly, resulting in uneven cell culture.

Method used

A piston device is designed to drive the drive gear and drive shaft to rotate by driving the motor, and then control the up and down movement of the piston in the first and second cylinders, so that the piston rods on both sides of the cradle move up and downward movement in turn, realizing the automatic sway of the cradle and ensuring uniform mixing of the harvest liquid.

Benefits of technology

The uniform shake of the harvesting liquid in the ten-layer cell factory is achieved, improving the uniformity and efficiency of cell culture.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223292563U_ABST
    Figure CN223292563U_ABST
Patent Text Reader

Abstract

The utility model discloses a piston device convenient for uniformly shaking cell factory harvest liquid, which relates to the field of uniformly shaking devices and comprises an equipment shell, a mounting notch is arranged at the upper end of the equipment shell, a movable shaft is movably mounted on the equipment shell, a cradle is fixedly mounted on the movable shaft, and a shaking mechanism is arranged in the equipment shell. The rocking mechanism comprises a first cylinder body and a second cylinder body which are fixedly mounted in the equipment shell, second pistons are movably mounted at the upper ends of the first cylinder body and the second cylinder body, piston rods are fixedly mounted on the second pistons, and the upper ends of the piston rods are movably mounted at the edge of the bottom of the cradle through hinges; first pistons are arranged at the bottoms of the first cylinder body and the second cylinder body, driving connecting rods are connected to the first pistons, and a driving mechanism is arranged between the first cylinder body and the second cylinder body. According to the piston device convenient for uniformly shaking the harvest liquid in the cell factory, the driving mechanism and the shaking mechanism are matched for use, so that the cradle can be driven to continuously and automatically swing, and the harvest liquid in a ten-layer cell factory is uniformly shaken.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the field of shaking devices, in particular to a piston device which is convenient for shaking harvested liquid in a cell factory. Background Art

[0002] The 10-layer Cell Factory is an advanced cell culture facility designed for large-scale cell culture. Its integrated ten-layer culture area effectively improves space utilization and reduces floor space, making it ideal for vaccine production, biopharmaceuticals, and laboratory research. Each layer is specially treated to ensure good cell attachment and rapid growth. Through optimized design and ease of operation, such as the use of dedicated manipulators to simplify the addition and removal of culture medium, efficient and stable cell culture is achieved.

[0003] Before harvesting viruses in a cell factory, the harvesting fluid needs to be fully mixed to completely remove the diseased cells in each layer. The ten-layer cell factory is large in size and heavy in weight, and it is difficult for a shaking device to evenly shake the harvesting fluid in the ten-layer cell factory. Therefore, a piston device is proposed to facilitate the use of the cell factory harvesting fluid. Utility Model Content

[0004] The purpose of the utility model is to provide a piston device which is convenient for shaking the harvested liquid of a cell factory, so as to solve the problem in the prior art that the harvested liquid is difficult to shake evenly.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a piston device for conveniently shaking the harvested liquid of a cell factory, comprising a device housing, a mounting notch being provided at the upper end of the device housing, a positioning base being fixedly installed at the bottom of the device housing, a movable shaft being movably installed on the device housing, a cradle being fixedly installed on the movable shaft, a shaking mechanism being provided in the device housing, the shaking mechanism comprising a first cylinder body and a second cylinder body being fixedly installed in the device housing, a second piston being movably installed at the upper end of each of the first cylinder body and the second cylinder body, a piston rod being fixedly installed on the second piston, and the piston The upper end of the rod is movably mounted on the bottom edge of the cradle through a hinge, and a first piston is provided at the bottom of the first cylinder body and the second cylinder body, and a driving connecting rod is connected to the first piston, and a driving mechanism is provided between the first cylinder body and the second cylinder body, and the driving mechanism includes a driving shaft movably mounted in the equipment housing, a driven gear is fixedly mounted in the middle position of the driving shaft, a driving motor is fixedly mounted on one side of the driven gear, and a driving gear is fixedly mounted on the output end of the driving motor, and driving disks are fixedly mounted on both ends of the driving shaft, and a connecting shaft is provided at the edge of the driving disk, and the driving disk can drive the connecting shaft to rotate.

[0006] Preferably, movable holes are provided at both ends of the driving connecting rod, one end of the driving connecting rod is movably mounted on the first piston, and the other end of the driving connecting rod is movably mounted at the edge of the driving disk, and the driving connecting rod can drive the first piston to move.

[0007] Preferably, hydraulic oil is stored in both the first cylinder and the second cylinder, and the movement of the first piston can drive the movement of the second piston.

[0008] Preferably, a positioning frame is provided in the device housing, the first cylinder body and the second cylinder body are both installed in the device housing through the positioning frame, and the piston rod is movably installed on the first cylinder body and the second cylinder body respectively through the second piston.

[0009] Preferably, a retaining frame is provided on the driving shaft, and the driving shaft is movably mounted in the device housing through the retaining frame, and the driving shaft can rotate on the retaining frame.

[0010] Preferably, the connecting shaft is connected to the driving connecting rod through a movable hole.

[0011] Preferably, the driving gear is movably mounted on one side of the driven gear through a driving motor, and the driving gear is meshed with the driven gear. The driving disk is movably mounted in the device housing through a driving shaft, and the driving motor can drive the driving gear to rotate.

[0012] Compared with the prior art, the beneficial effects of the present invention are:

[0013] In the present application, the first cylinder and the second piston in the second cylinder can be controlled to move up and down, wherein when the second piston in the first cylinder moves upward, the second piston in the second cylinder moves downward, thereby causing the piston rods on both sides of the cradle to move up and down in sequence. After the piston rods on both sides of the cradle move up and down in sequence, they will drive the cradle to swing, thereby shaking the harvested liquid in the ten-layer cell factory evenly.

[0014] The present application can drive the driving gear to rotate through the driving motor, thereby driving the driving shaft to rotate. After the driving shaft rotates, it will drive the driving plates at both ends to rotate. After the driving plates rotate, the driving connecting rod will drive the first piston to move forward and backward. When the first piston in the first cylinder moves forward, the first piston in the second cylinder will move backward, thereby driving the piston rod to move up and down in sequence, controlling the cradle to swing continuously and automatically. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2 This is a cross-sectional view of the overall structure of the utility model;

[0017] Figure 3 It is a schematic diagram of the local structure of the utility model;

[0018] Figure 4 This is a schematic diagram of the shaking mechanism of the utility model;

[0019] Figure 5 This is a schematic diagram of the driving mechanism of the present utility model.

[0020] Numbers in the figure: 1. Equipment housing; 2. Movable shaft; 3. Cradle; 4. Positioning base; 5. Mounting notch; 6. Rocking mechanism; 601. Piston rod; 602. First cylinder; 603. First piston; 604. Driving connecting rod; 605. Movable hole; 606. Second piston; 607. Second cylinder; 7. Driving mechanism; 701. Retaining frame; 702. Driving disk; 703. Connecting shaft; 704. Driving gear; 705. Driving motor; 706. Driven gear; 707. Driving shaft. DETAILED DESCRIPTION

[0021] The following will be combined with the accompanying drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0022] like Figure 1 、 Figure 2 and Figure 3 As shown, the utility model provides a technical solution of a piston device for facilitating the shaking of harvested liquid in a cell factory, comprising a device housing 1, a mounting notch 5 being provided at the upper end of the device housing 1, a positioning base 4 being fixedly installed at the bottom of the device housing 1, a movable shaft 2 being movably installed on the device housing 1, a cradle 3 being fixedly installed on the movable shaft 2, a shaking mechanism 6 being provided in the device housing 1, a driving mechanism 7 being provided between the first cylinder body 602 and the second cylinder body 607, and the driving mechanism 7 being used in conjunction with the shaking mechanism 6, the cradle 3 can be continuously and automatically swung to shake the harvested liquid in the ten-layer cell factory.

[0023] like Figure 3 and Figure 4As shown, the rocking mechanism 6 includes a first cylinder body 602 and a second cylinder body 607 fixedly mounted in the device housing 1, and a second piston 606 is movably mounted on the upper end of the first cylinder body 602 and the second cylinder body 607, a piston rod 601 is fixedly mounted on the second piston 606, and the upper end of the piston rod 601 is movably mounted on the bottom edge of the cradle 3 through a hinge, a first piston 603 is provided at the bottom of the first cylinder body 602 and the second cylinder body 607, a driving connecting rod 604 is connected to the first piston 603, and movable holes 605 are provided at both ends of the driving connecting rod 604, one end of the driving connecting rod 604 is movably mounted on the first piston 603, and the other end of the driving connecting rod 604 is movably mounted on the edge of the driving disk 702.

[0024] Specifically, the second piston 606 in the first cylinder 602 and the second cylinder 607 can be controlled to move up and down, wherein the second piston 606 in the first cylinder 602 moves upward and the second piston 606 in the second cylinder 607 moves downward, thereby causing the piston rods 601 on both sides of the cradle 3 to move up and down in sequence. After the piston rods 601 on both sides of the cradle 3 move up and down in sequence, they will drive the cradle 3 to swing, thereby shaking the harvested liquid in the ten-layer cell factory evenly.

[0025] like Figure 3 and Figure 5 As shown, the driving mechanism 7 includes a driving shaft 707 movably mounted in the device housing 1, a driven gear 706 is fixedly mounted in the middle position of the driving shaft 707, a driving motor 705 is fixedly mounted on one side of the driven gear 706, a driving gear 704 is fixedly mounted on the output end of the driving motor 705, driving disks 702 are fixedly mounted at both ends of the driving shaft 707, a connecting shaft 703 is provided at the edge of the driving disk 702, a retaining frame 701 is provided on the driving shaft 707, and the driving shaft 707 is movably mounted in the device housing 1 through the retaining frame 701.

[0026] Specifically, the driving motor 705 can drive the driving gear 704 to rotate, thereby driving the driving shaft 707 to rotate. After the driving shaft 707 rotates, it will drive the driving disks 702 at both ends to rotate. After the driving disks 702 rotate, the driving connecting rod 604 will drive the first piston 603 to move back and forth. When the first piston 603 in the first cylinder body 602 moves forward, the first piston 603 in the second cylinder body 607 will move backward, thereby driving the piston rod 601 to move up and down in sequence, controlling the cradle 3 to swing continuously and automatically.

[0027] Working principle: When in use, first place the ten-layer cell factory in the cradle 3, then start the drive motor 705. After starting the drive motor 705, it will drive the drive gear 704 to rotate. Since the drive gear 704 is movably installed on one side of the driven gear 706 through the drive motor 705, and the drive gear 704 and the driven gear 706 are engaged together, the rotating drive gear 704 will drive the driven gear 706 to rotate. After the driven gear 706 rotates, it will drive the drive shaft 707 to rotate. After the drive shaft 707 rotates, it will drive the drive disks 702 at both ends to rotate. After the drive disk 702 rotates, it drives the connecting rod 604 will drive the first piston 603 to move forward and backward, and when the first piston 603 in the first cylinder 602 moves forward, the first piston 603 in the second cylinder 607 will move backward, thereby controlling the first cylinder 602 and the second piston 606 in the second cylinder 607 to move up and down, wherein when the second piston 606 in the first cylinder 602 moves upward, the second piston 606 in the second cylinder 607 moves downward, thereby causing the piston rods 601 on both sides of the cradle 3 to move up and down in sequence. After the piston rods 601 on both sides of the cradle 3 move up and down in sequence, they will drive the cradle 3 to swing, thereby shaking the harvested liquid in the ten-layer cell factory evenly.

[0028] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the present invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the present invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be encompassed within the present invention. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

Claims

1. A piston device for facilitating the shaking of harvested liquid in a cell factory, comprising a device housing (1), a mounting notch (5) being provided at the upper end of the device housing (1), a positioning base (4) being fixedly mounted at the bottom of the device housing (1), a movable shaft (2) being movably mounted on the device housing (1), and a cradle (3) being fixedly mounted on the movable shaft (2), characterized in that: The device housing (1) is provided with a rocking mechanism (6), and the rocking mechanism (6) comprises a first cylinder (602) and a second cylinder (607) fixedly installed in the device housing (1), a second piston (606) is movably installed on the upper end of the first cylinder (602) and the second cylinder (607), a piston rod (601) is fixedly installed on the second piston (606), and the upper end of the piston rod (601) is movably installed on the bottom edge of the cradle (3) through a hinge, a first piston (603) is provided on the bottom of the first cylinder (602) and the second cylinder (607), and a driving mechanism (603) is connected to the first piston (603). A connecting rod (604) is provided between the first cylinder body (602) and the second cylinder body (607), wherein the driving mechanism (7) comprises a driving shaft (707) movably mounted in the device housing (1), a driven gear (706) is fixedly mounted in the middle of the driving shaft (707), a driving motor (705) is fixedly mounted on one side of the driven gear (706), a driving gear (704) is fixedly mounted on the output end of the driving motor (705), a driving disk (702) is fixedly mounted at both ends of the driving shaft (707), and a connecting shaft (703) is provided at the edge of the driving disk (702).

2. A piston device for facilitating the shaking of harvested liquid from a cell factory according to claim 1, characterized in that: Both ends of the driving connecting rod (604) are provided with movable holes (605). One end of the driving connecting rod (604) is movably mounted on the first piston (603), and the other end of the driving connecting rod (604) is movably mounted on the edge of the driving disk (702).

3. The piston device for facilitating the shaking of cell factory harvest fluid according to claim 2, characterized in that: Hydraulic oil is stored in both the first cylinder (602) and the second cylinder (607).

4. The piston device for facilitating the shaking of harvested liquid from a cell factory according to claim 3, characterized in that: A positioning frame is provided in the device housing (1), and the first cylinder body (602) and the second cylinder body (607) are both installed in the device housing (1) through the positioning frame. The piston rod (601) is movably installed on the first cylinder body (602) and the second cylinder body (607) respectively through the second piston (606).

5. The piston device for facilitating the shaking of harvested liquid from a cell factory according to claim 4, characterized in that: A retaining frame (701) is provided on the driving shaft (707), and the driving shaft (707) is movably mounted in the device housing (1) via the retaining frame (701).

6. The piston device for facilitating the shaking of harvested liquid from a cell factory according to claim 1, characterized in that: The connecting shaft (703) is connected to the driving connecting rod (604) through the movable hole (605).

7. The piston device for facilitating the shaking of harvested liquid from a cell factory according to claim 1, characterized in that: The driving gear (704) is movably mounted on one side of the driven gear (706) via the driving motor (705), and the driving gear (704) and the driven gear (706) are meshed together. The driving disc (702) is movably mounted in the device housing (1) via the driving shaft (707).