High-pressure-resistant immobilized continuous production equipment with adjustable filling height

Abstract

The utility model discloses high-pressure-resistant immobilized continuous production equipment with adjustable filling height. The high-pressure-resistant immobilized continuous production equipment comprises a reaction chamber, a solid carrier filler feeder, a bottom solid carrier baffle, a bottom high-pressure sealing ring, a bottom fixing part, a top solid carrier baffle, a top high-pressure sealing ring, a top fixing part, temperature detection equipment and an external heating device. According to the utility model, the problems that the filler height of the traditional immobilized reactor cannot be adjusted at will and the filling of the immobilized filler is complicated can be solved; the problem of non-uniform filling of solid objects is solved; the problem of high pressure resistance of the immobilized reactor is solved; the problem of immobilization of the immobilized filler in the reactor is solved, so that reactants can enter the reactor from bottom to top; the design structure is optimized, pipeline connection penetrating through the heat exchange layer and the reactor is avoided, and the safety problem is solved; the maximization of the use of the immobilized reactor is realized, and the consumption of manpower and material resources is reduced.

Description

Technical Field

[0001] The utility model belongs to the technical field of chemical industry and pharmaceutical industry, and in particular relates to a high-pressure resistant and continuous production solid-load reactor, and specifically relates to a high-pressure resistant solid-load continuous production device with adjustable filling height. Background Art

[0002] Common solid-support reactions in continuous chemical manufacturing processes include enzyme-supported reactions, acid-supported reactions, and catalyst-supported reactions. These reactions require the filling and replacement of the solid support, while ensuring that the support remains stationary to promote uniform contact with the reaction liquid. Some reactions may involve intense heat release, high temperature and pressure, or gas-liquid two-phase reactions, requiring the solid-supported reactor to possess excellent heat transfer, pressure resistance, and corrosion resistance.

[0003] There are two main types of solid-support reactors commonly used in industry: 1. Low-pressure, bottom-inlet, top-outlet, spiral-type, pressurized solid-support reactors; and 2. High-pressure, top-inlet, bottom-outlet, filled, pressurized solid-support reactors. However, both types of solid-support reactors have their inherent drawbacks.

[0004] Attachment Figure 1 A partial view of a low-pressure, bottom-in, top-out spiral-pressed solid-load reactor is shown. Components such as the temperature display 81, solid-load inlet 82, heat exchange jacket 83, material outlet 84, filter head 85, heat exchange fluid outlet 86, solid-load packing 87, lifting screw 88, and press rotary handgrip 89 are labeled. A disadvantage of this solid-load reactor is that it relies solely on the contact seal between the filter head 85 and the interior of the chamber, making it unsuitable for high pressures. Furthermore, the filter head 85 moves up and down as the press rotary handgrip 89 rotates, causing scratches on the seal between the filter head 85 and the interior of the chamber, resulting in airtight leaks. Furthermore, the thermometer must pass through the heat exchange jacket 83 to contact the solid-load packing 87. If the connection is not handled properly, leaks from the joint buried in the heat exchange fluid could cause contamination and danger.

[0005] Attachment Figure 2 The diagram shows a partial structural diagram of a high-pressure, top-inlet, bottom-outlet, filled, pressurized solid-loaded reactor. Components such as a temperature display 91, a solid-loaded inlet 92, a heat exchange jacket 93, a material inlet 94, a pressurized material 95, a heat exchange fluid outlet 96, and a solid-loaded filler 97 are labeled. A disadvantage of this solid-loaded reactor is that material can only be fed in from the top and discharged from the bottom. If material is fed in from the bottom and discharged from the top, the solid-loaded filler 97 will move and escape. Furthermore, with top-inlet and bottom-out, the material cannot completely fill the entire reaction column, reducing the contact time between the material and the solid-loaded solid. Utility Model Content

[0006] In view of the fact that the existing solid-loaded reactor cannot simultaneously meet the requirements of high-pressure resistance, material inlet and outlet, and equipment matching requirements of different filling heights, the utility model provides a high-pressure resistant solid-loaded continuous production equipment with adjustable filling height. The specific technical solutions adopted by the utility model are as follows:

[0007] A high-pressure-resistant solid-load continuous production device with adjustable filling height, characterized by comprising a reaction chamber, a solid-load filler feeder, a bottom solid-load baffle, a bottom high-pressure sealing ring, a bottom fixing component, a top solid-load baffle, a top high-pressure sealing ring, a top fixing component, a temperature detection device, and an external heating device;

[0008] The end of the solid-loaded filler feeder is in communication with the wall of the reaction chamber, and the solid-loaded filler enters the reaction chamber through the solid-loaded filler feeder;

[0009] The bottom solid load baffle is installed on the bottom of the equipment by the bottom fixing component, and the bottom solid load baffle supports the solid load filler;

[0010] The top solid carrier baffle is installed on the top of the device by the top fixing component; the bottom solid carrier baffle, the top solid carrier baffle, and the reaction chamber form a closed space;

[0011] The temperature detection device includes a temperature detector and a temperature sleeve, wherein the detection head of the temperature detector is located between the top solid support baffle and the bottom solid support baffle in the reaction chamber;

[0012] The reaction chamber is further provided with a material inlet and a material outlet. The material inlet is arranged at the lower end of the reaction chamber, and the material outlet is arranged at the upper end of the reaction chamber.

[0013] In some specific embodiments, the cross section of the bottom solid load baffle is annular, a filter screen is provided inside the bottom solid load baffle, and the bottom tip of the bottom solid load baffle is through and connected to the solid load filler outlet pipe to form a solid load filler outlet.

[0014] In some specific embodiments, the bottom fixing component includes a bottom flange, a flange fixing hoop, a flange fixing cover, and a bottom ferrule; the bottom flange includes a bottom upper flange and a bottom lower flange, which are restrained by the flange fixing hoop and the flange fixing cover; the bottom ferrule fixes the bottom lower flange to the solid load filler outlet pipe.

[0015] In some specific embodiments, the cross section of the top solid load baffle is annular, a filter is provided inside the top solid load baffle, and the top tip of the top solid load baffle is through and connected to the temperature sleeve to form a passage for the temperature probe to pass through.

[0016] In some specific embodiments, the top fixing component includes a top flange, a flange fixing hoop, a flange fixing cover, a first high-pressure ferrule, a second high-pressure ferrule, and a lifting screw; the top flange includes a top upper flange and a top lower flange, which are restrained by the flange fixing hoop and the flange fixing cover; the first high-pressure ferrule fixes the top upper flange to the temperature sleeve, and the second high-pressure ferrule fixes the lifting screw to the temperature sleeve.

[0017] In some specific embodiments, the external heating device is a heat exchange jacket, the heat exchange fluid inlet is arranged below the heat exchange jacket, and the heat exchange fluid outlet is arranged above the heat exchange jacket.

[0018] In some specific embodiments, the external heating device is further provided with a heat-insulating layer on the outside.

[0019] In some specific embodiments, a sealing opening is provided at the lower end of the reaction chamber near the bottom solid support baffle, and the sealing opening is stepped and is used for accommodating the bottom high-pressure sealing ring.

[0020] In some specific embodiments, the temperature detection device further includes a temperature display.

[0021] In some specific embodiments, a plurality of the devices are connected in series in sequence through a pipeline, and the material outlet of the front-end device is connected to the material inlet of the back-end device through the pipeline.

[0022] Compared with the prior art, the present invention has the following beneficial effects:

[0023] It solves the problem that traditional solid-loaded reactors cannot simultaneously meet the requirements of high pressure resistance and bottom-in and top-out; it solves the problems that the height of the solid-loaded filler cannot be adjusted arbitrarily and the loading of the solid-loaded filler is cumbersome; it maximizes the use of the solid-loaded reactor and reduces the consumption of manpower and material resources.

[0024] The concept, specific structure and technical effects of the present invention will be further described below in conjunction with the accompanying drawings to fully understand the purpose, characteristics and effects of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a schematic diagram of the partial structure of a low-pressure bottom-inlet and top-out spiral pressure-pressed solid-loaded reactor.

[0026] Figure 2 It is a schematic diagram of the partial structure of a high-pressure top-inlet and bottom-out filled pressurized solid-loaded reactor.

[0027] Figure 3 It is a structural schematic diagram of the solid-supported reactor of the utility model.

[0028] Figure 4The bottom structure diagram of the solid-supported reactor of the present invention is shown in FIG. (a) is a schematic diagram of the structure before assembly, and (b) is a schematic diagram of the structure after assembly.

[0029] Figure 5 The following are partial structural diagrams of the bottom solid load baffle of the present invention. (a) is a structural diagram of the bottom solid load baffle fixed to the bottom lower flange; (b) is a structural diagram of the bottom solid load baffle and the high-pressure sealing ring.

[0030] Figure 6 The top structure diagram of the solid-supported reactor of the present invention is shown in FIG. (a) is a schematic diagram of the structure when the solid-supported filler is added; and (b) is a schematic diagram of the structure after the solid-supported filler is added.

[0031] Figure 7 The following are partial structural diagrams of the top solid load baffle of the present invention. (a) is a structural diagram of the top solid load baffle and the temperature sleeve; (b) is a structural diagram of the top solid load baffle and the high-pressure sealing ring.

[0032] Figure 8 It is a schematic diagram of the internal structure of the high-pressure ferrule of the utility model.

[0033] Figure 9 This is a schematic diagram of the serial use of multiple solid-support reactors of the present invention.

[0034] Description of the marks in the figure:

[0035] 1. Solid load filler inlet; 2. Insulation layer; 3. Heat exchange jacket; 4. Temperature sleeve; 5. Solid load filler; 6. Bottom solid load baffle; 7. Solid load filler outlet; 8. Temperature display; 9. Lifting filter head; 10. Top flange connection; 11. Material outlet; 12. Heat exchange fluid outlet; 13. Heat exchange fluid inlet; 14. Material inlet; 15. Bottom flange connection; 16. Top solid load baffle.

[0036] 21. Sealing port; 22. High-pressure sealing ring; 23. Flange fixing cover; 24. Half-crescent flange fixing hoop; 25. Solid load filler outlet; 26. Filter screen; 27. Bottom lower flange; 28. Bottom ferrule.

[0037] 31. Lifting screw; 32. Solids filler feeder; 33. High-pressure ferrule.

[0038] 41. Compression fitting; 42. High-pressure sealing ring; 43. Filter; 44. Straight-through sleeve.

[0039] 51. High-pressure front ferrule; 52. High-pressure rear ferrule; 53. High-pressure ferrule cap.

[0040] 81. Temperature display; 82. Solid load inlet; 83. Heat exchange jacket; 84. Material outlet; 85. Filter head; 86. Heat exchange liquid outlet; 87. Solid filler; 88. Lifting screw; 89. Pressing rotary handshake.

[0041] 91. Temperature display; 92. Solid load inlet; 93. Heat exchange jacket; 94. Material inlet; 95. Filling press; 96. Heat exchange liquid outlet; 97. Solid load filler. DETAILED DESCRIPTION

[0042] In order to make the technical means, creative features, objectives and effects of the utility model easier to understand, the utility model is further explained below with reference to specific diagrams. However, the utility model is not limited to the following implementation cases.

[0043] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings in this specification are only used to match the contents disclosed in the specification so that people familiar with this technology can understand and read them. They are not used to limit the conditions under which the present invention can be implemented. Therefore, they have no substantive technical significance. Any structural modifications, changes in proportional relationships, or adjustments in size should still fall within the scope of the technical contents disclosed in this utility model without affecting the efficacy and purpose that can be achieved by the present utility model.

[0044] Example 1

[0045] Figure 3 This is a schematic diagram of the structure of the solid-loaded reactor of the present invention, in which are marked the solid-loaded filler inlet 1, insulation layer 2, heat exchange jacket 3, temperature sleeve 4, solid-loaded filler 5, bottom solid-loaded baffle 6, solid-loaded filler outlet 7, temperature display 8, lifting filter head 9, top flange connection 10, material outlet 11, heat exchange liquid outlet 12, heat exchange liquid inlet 13, material inlet 14, bottom flange connection 15, and top solid-loaded baffle 16.

[0046] The solid filler 5 enters the reaction chamber through the solid filler inlet 1. A bottom solid filler baffle 6 is provided at the bottom of the reaction chamber for receiving the solid filler 5. A top solid filler baffle 16 is provided at the top of the reaction chamber. In the working state, the solid filler 5 is located between the top solid filler baffle 16 and the bottom solid filler baffle 6, and the upper and lower ends of the solid filler 5 are in close contact with the top solid filler baffle 16 and the bottom solid filler baffle 6, respectively.

[0047] like Figure 4 、 Figure 5As shown, the cross-section of the bottom solid load baffle 6 is annular. When in operation, it is in close contact with the annular high-pressure sealing ring 22, forming a good airtightness. A filter screen 26 is provided in the bottom solid load baffle 6. When the reaction material enters from the bottom and exits from the top, it can pass through the filter screen 26 and flow through the solid load filler 5. The bottom tip of the bottom solid load baffle 6 is through-hole and connected to the solid load filler outlet pipe, forming the solid load filler outlet 7. Before the reaction, the bottom solid load baffle 6 is adjusted to a suitable position. For example, after its upper end is in close contact with the high-pressure sealing ring 22 placed at the sealing port 21, the bottom lower flange 27 is pushed to a position close to the bottom upper flange, and the bottom lower flange 27 is fixed to the solid load filler outlet pipe using the bottom clamp 28. Then, the flange device is locked. In this way, the position of the bottom solid load baffle 6 can be fixed.

[0048] like Figure 6 、 Figure 7 As shown, the top solid load baffle 16 has an annular cross-section and, when in operation, is in close contact with the annular high-pressure sealing ring 42, ensuring a good seal. A filter screen 43 is provided within the top solid load baffle 16. As the reaction material enters from below and exits from above, it can flow through the solid load packing 5 and then through the filter screen 43. The top tip of the top solid load baffle 16 is through-hole and connected to the temperature sleeve 4, forming a passage for the temperature probe. Before the reaction, the solid load packing is added to the reaction chamber, and then the top solid load baffle 16 is adjusted to the appropriate position and locked. For example, the top solid load baffle 16 is allowed to naturally fall to the top of the solid load packing 5 before being locked in place.

[0049] The temperature detector is connected to an external temperature display 8 so that the temperature in the reaction chamber can be quickly displayed on the temperature display 8. A heat exchange jacket 3 is provided on the outside of the reaction chamber for flowing a heat exchange fluid through it, thereby changing the temperature in the reaction chamber. An insulating layer 2 is also provided on the outside of the heat exchange jacket 3 to maintain the temperature of the heat exchange fluid and reduce the heat energy loss of the heat exchange fluid. The reaction material enters the reaction chamber through the material inlet 14, then passes through the filter screen 26 in the bottom solid support baffle 6, and then fully contacts the solid support filler 5 filled in the reaction chamber. Thereafter, the reaction material passes through the filter screen 43 in the top solid support baffle 16 and leaves the solid support reactor through the material outlet 11, forming a bottom-in, top-out material flow path. Simultaneously, the heat exchange fluid enters the heat exchange jacket 3 through the heat exchange fluid inlet 13 and leaves the solid support reactor through the heat exchange fluid outlet 12. Because the entire reaction chamber remains sealed, the system can maintain a high pressure state.

[0050] Example 2

[0051] Figure 4 This is a schematic diagram of the bottom structure of the solid-supported reactor of the utility model. Figure 5 It is a schematic diagram of the local structure of the bottom solid load baffle of the utility model.

[0052] Before the reaction begins, place the high-pressure sealing ring 22 on the step of the sealing opening 21 and secure the bottom solid load baffle 6 against the high-pressure sealing ring 22. Secure the upper and lower bottom flanges with the crescent-shaped flange fixing hoop 24, and secure the bottom solid load baffle 6 to the bottom lower flange 27 with the bottom clamping sleeve 28. Place the annular flange fixing cover 23 over the double crescent-shaped flange fixing hoop 24 to prevent the double crescent-shaped flange fixing hoop 24 from separating. Tighten the screws on the double crescent-shaped flange fixing hoop 24 to securely connect the upper and lower flanges; tighten the screws on the annular flange fixing cover 23 to connect it to the double crescent-shaped flange fixing hoop 24.

[0053] Example 3

[0054] Figure 6 This is a schematic diagram of the top structure of the solid-supported reactor of the utility model. Figure 7 It is a schematic diagram of the local structure of the top solid load baffle of the utility model.

[0055] Before adding the solid material, loosen the two high-pressure ferrules 33. Then, adjust the lifting screw 31 to raise the top solid baffle 16 to the upper end of the solid material inlet. Open the valve of the solid material feeder 32 and add the solid material to the reactor. After adding, adjust the lifting screw 31 so that the top solid baffle 16 naturally falls to the top of the solid material 5. Tighten the fixing bolts on the lifting screw 31 to connect it to the reactor, securing it. Finally, tighten the high-pressure ferrule 33 to achieve a high-pressure seal.

[0056] Figure 7 A ferrule joint 41 is fixed to the temperature sleeve 4 in (a), and the ferrule joint 41 is connected to the lower component in the figure using existing technology such as threaded connection.

[0057] Figure 8 A schematic diagram of the internal structure of the high-pressure ferrule is shown, including a high-pressure sealing ring 22, a high-pressure front ferrule 51, a high-pressure rear ferrule 52, and a high-pressure ferrule cap 53. During operation, the above components are tightly connected, the high-pressure sealing ring 22 is placed on the high-pressure front ferrule 51, the high-pressure front ferrule 51 and the high-pressure rear ferrule 52 are tightly fitted together, the high-pressure ferrule cap 53 tightly fastens the high-pressure front ferrule 51 and the high-pressure rear ferrule 52, and the temperature sleeve 4 passes through the middle of the above components.

[0058] Example 4

[0059] In some cases, multiple solid-supported reactors can be used in series, e.g. Figure 9 As shown, the material outlet of the front-end device is connected to the material inlet of the back-end device through a pipeline, and an appropriate number of solid-support reactors are used as needed to achieve the purpose of expanding production capacity.

[0060] The utility model designs a high-pressure resistant solid-load continuous production equipment with easy replacement of solid fillers, reasonable design position of temperature probe, and material inlet and outlet at any filling height, thereby maximizing the use of solid-load equipment, improving equipment utilization, reducing the amount of solid-load fillers used, and reducing the consumption of manpower and material resources. The utility model can solve the problems of traditional solid-load reactors in which the filler height cannot be arbitrarily adjusted and the loading of solid-load fillers is cumbersome; solve the problem of uneven solid-load filling; solve the problem of high-pressure resistance of solid-load reactors; solve the problem of fixing the solid-load fillers in the reactor, allowing reactants to enter the reactor from the bottom and exit from the top; optimize the design structure, eliminate the need for pipe connections that pass through the heat exchange layer and the reactor, and solve safety issues; maximize the use of solid-load reactors and reduce the consumption of manpower and material resources.

[0061] The above describes in detail the preferred embodiments of the present invention. It should be understood that numerous modifications and variations based on the concepts of the present invention can be made by those skilled in the art without inventive effort. Therefore, any technical solution that can be derived by a person skilled in the art based on the concepts of the present invention through logical analysis, reasoning, or limited experimentation based on the existing technology shall be within the scope of protection defined by the claims.

Claims

1. A high-pressure resistant solid-load continuous production equipment with adjustable filling height, characterized in that: It includes a reaction chamber, a solid load filler feeder, a bottom solid load baffle, a bottom high-pressure sealing ring, a bottom fixing component, a top solid load baffle, a top high-pressure sealing ring, a top fixing component, a temperature detection device, and an external heating device; The end of the solid-loaded filler feeder is in communication with the wall of the reaction chamber, and the solid-loaded filler enters the reaction chamber through the solid-loaded filler feeder; The bottom solid load baffle is installed on the bottom of the equipment by the bottom fixing component, and the bottom solid load baffle supports the solid load filler; The top solid carrier baffle is installed on the top of the device by the top fixing component; the bottom solid carrier baffle, the top solid carrier baffle, and the reaction chamber form a closed space; The temperature detection device includes a temperature detector and a temperature sleeve, wherein the detection head of the temperature detector is located between the top solid support baffle and the bottom solid support baffle in the reaction chamber; The reaction chamber is further provided with a material inlet and a material outlet. The material inlet is arranged at the lower end of the reaction chamber, and the material outlet is arranged at the upper end of the reaction chamber.

2. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The cross section of the bottom solid load baffle is annular, a filter screen is provided inside the bottom solid load baffle, and the bottom tip of the bottom solid load baffle is through and connected to the solid load filler outlet pipe to form a solid load filler outlet.

3. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 2, characterized in that: The bottom fixing component includes a bottom flange, a flange fixing hoop, a flange fixing cover, and a bottom clamp; the bottom flange includes a bottom upper flange and a bottom lower flange, which are fixed by the flange fixing hoop and the flange fixing cover; the bottom clamp fixes the bottom lower flange to the solid load filler outlet pipe.

4. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The cross section of the top solid load baffle is annular, a filter screen is provided inside the top solid load baffle, and a top tip of the top solid load baffle is passed through and connected to the temperature sleeve to form a passage for the temperature detector to pass through.

5. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 4, characterized in that: The top fixing component includes a top flange, a flange fixing hoop, a flange fixing cover, a first high-pressure ferrule, a second high-pressure ferrule, and a lifting screw; the top flange includes a top upper flange and a top lower flange, which are fixed by the flange fixing hoop and the flange fixing cover; the first high-pressure ferrule fixes the top upper flange to the temperature sleeve, and the second high-pressure ferrule fixes the lifting screw to the temperature sleeve.

6. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The external heating device is a heat exchange jacket, the heat exchange liquid inlet is arranged below the heat exchange jacket, and the heat exchange liquid outlet is arranged above the heat exchange jacket.

7. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to any one of claims 1 or 6, characterized in that: A heat preservation layer is also provided outside the external heating device.

8. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 1, characterized in that: A sealing opening is provided at the lower end of the reaction chamber near the bottom solid load baffle. The sealing opening is step-shaped and is used to place the bottom high-pressure sealing ring.

9. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The temperature detection device also includes a temperature display.

10. The high-pressure resistant solid-load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The plurality of devices are connected in series in sequence through pipelines, and the material outlet of the front-end device is connected to the material inlet of the back-end device through the pipeline.

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