Biosafety cabinet for PCR (Polymerase Chain Reaction) inspection

By introducing a combination design of longitudinal conveying channels, transverse storage chambers and ultraviolet lights into the biosafety cabinet for PCR inspection, the problems of air inflow and surface bacterial residues during container insertion are solved, and automated sterilization and safety improvement are achieved.

CN223304447UActive Publication Date: 2025-09-05FOURTH MILITARY MEDICAL UNIVERSITY
View PDF 1 Cites 0 Cited by

Patent Information

Application Number
CN202422400629.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-30
Publication Date
2025-09-05
Estimated Expiration
2034-09-30

AI Technical Summary

Technical Problem

During the PCR inspection, when the cabinet is opened and placed in the container to be inspected, air flows into the inside of the cabinet, and bacteria may remain on the outer surface of the container, posing a biological safety hazard.

Method used

A biosafety cabinet is designed, which includes a longitudinal conveying channel and a transverse storage chamber in the safety cabinet, equipped with a driving component and a conveyor, and an ultraviolet light is installed in the conveyor, which automatically feeds and discharges through electric push rods and drive parts, and sterilizes with ultraviolet lights.

Benefits of technology

It realizes sterilization treatment of air and container surface during automatic feeding and discharge, prevents bacteria from entering the safety cabinet, and improves biosafety.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223304447U_ABST
    Figure CN223304447U_ABST
Patent Text Reader

Abstract

The utility model relates to the technical field of PCR (Polymerase Chain Reaction) inspection, and discloses a biological safety cabinet for PCR inspection, which comprises a safety cabinet body, a plurality of transverse storage cavities are distributed in the safety cabinet body at equal intervals, a longitudinal conveying channel is longitudinally arranged in the safety cabinet body, and the transverse storage cavities are communicated with the longitudinal conveying channel. The interior of the longitudinal conveying channel communicates with the interiors of the transverse storage cavities, an opening is formed in one end of the longitudinal conveying channel, the opening of the longitudinal conveying channel is formed in the exterior of the safety cabinet body, and a driving assembly is installed in the longitudinal conveying channel; a conveyor connected with the driving assembly is movably mounted in the longitudinal conveying channel, an ultraviolet lamp is mounted in the conveyor, a to-be-detected container is placed in the conveyor, and the ultraviolet lamp is mounted in the conveyor, so that air entering the conveyor and the surface of the container can be sterilized; and bacteria are prevented from entering the safety cabinet body.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of PCR testing, in particular to a biological safety cabinet used for PCR testing. Background Art

[0002] With the increasing interest in DNA testing in my country, laboratory testing is being carried out on a large scale. The use of cabinets in these tests not only ensures the safety of inspectors but also enables new breakthroughs in PCR testing. Cabinets are box-shaped, air-purifying, negative-pressure safety devices that prevent the release of aerosols containing dangerous or unknown biological particles during testing operations. They are widely used in research, teaching, clinical testing, and production in fields such as microbiology, biomedicine, genetic engineering, and biological products. They are the most fundamental safety protection device in the first-level protective barrier of laboratory biosafety. The cabinet's operating principle is to draw air outward from the cabinet, maintaining a negative pressure inside and protecting personnel through vertical airflow. Outside air is filtered through a high-efficiency air filter before entering the safety cabinet to prevent contamination of processed samples. The air inside the cabinet is also filtered through a HEPA filter before being released into the atmosphere to protect the environment.

[0003] In the prior art, a biosafety cabinet for PCR testing, authorized with publication number CN210711580U, comprises a cabinet body, a PCR detector mounted on the inside of the cabinet body, a storage box mounted on one side of the PCR detector body, a groove provided at the top of the storage box, the groove being the same size as the outer sides of an enzyme reservoir and a water tank, the storage box being connected to the enzyme reservoir and the water tank via a slot, a water tank mounted on the top of the storage box, an enzyme reservoir mounted on one side of the water tank, a motor mounted on the outside of the cabinet body, a rotating shaft mounted on one side of the motor, and a rotating block mounted on the outer side of the rotating shaft. By installing an intelligent pipette within the safety cabinet, multiple enzymes can be drawn up at once, and the enzymes to be tested can be quickly and easily placed into the PCR detector.

[0004] In the above technical solution, the cabinet needs to be opened during storage and the containers to be tested need to be placed in the cabinet. This process will cause air to flow into the cabinet and bacteria may remain on the outer surface of the container. For this reason, we propose a biosafety cabinet for PCR testing. Utility Model Content

[0005] The utility model provides a biosafety cabinet for PCR testing, which solves the technical problem that the cabinet needs to be opened during storage to place containers to be tested into the cabinet, which causes air to flow into the cabinet and bacteria to remain on the outer surface of the container.

[0006] In order to solve the above technical problems, the utility model provides a biological safety cabinet for PCR testing, including a safety cabinet body, a plurality of horizontal storage cavities equidistantly distributed inside the safety cabinet body, a longitudinal conveying channel is longitudinally arranged inside the safety cabinet body, the interior of the longitudinal conveying channel is connected with the interiors of the plurality of horizontal storage cavities, an opening is provided at one end of the longitudinal conveying channel, the opening of the longitudinal conveying channel is provided outside the safety cabinet body, a driving assembly is installed inside the longitudinal conveying channel, a conveyor connected to the driving assembly is movably installed inside the longitudinal conveying channel, and an ultraviolet lamp is installed inside the conveyor.

[0007] Preferably, a connection port is provided through one end of the conveyor for connecting to the transverse storage cavity.

[0008] Preferably, the driving assembly includes an electric guide rail, which is fixedly installed on the inner bottom of the longitudinal conveying channel. An electric guide rail moving end is provided on the electric guide rail, and the electric guide rail moving end is fixedly connected to the conveyor.

[0009] Preferably, the drive assembly further comprises a plurality of electric push rods, and the plurality of electric push rods are fixedly mounted on the outside of the safety cabinet via a mounting frame.

[0010] Preferably, a plurality of the electric push rods are arranged in a one-to-one correspondence with a plurality of transverse storage cavities, and the output end of each of the electric push rods movably extends into the interior of the corresponding transverse storage cavity and is fixedly connected to a driving member.

[0011] Preferably, each of the transverse storage cavities is provided with an opening at one end away from the longitudinal conveying channel, and the opening is provided on the outer wall of the safety cabinet, and a first sealing plate for sealing the opening is installed in a lifting and sliding manner at the opening of the transverse storage cavity.

[0012] Preferably, a second sealing plate for sealing the opening is installed in a lifting and sliding manner at the opening of the longitudinal conveying channel.

[0013] Preferably, a cabinet roof is installed on the top of the safety cabinet body, and an inspection component is installed on the lower surface of the cabinet roof inside each transverse storage cavity.

[0014] Compared with related technologies, the biosafety cabinet for PCR testing provided by the present invention has the following beneficial effects:

[0015] When in use, the container to be tested is placed inside the conveyor, and the ultraviolet lamp installed inside the conveyor can sterilize the air entering the conveyor and the surface of the container to prevent bacteria from entering the interior of the safety cabinet.

[0016] During use, the electric push rod can drive the driving member to move to the connection port of the conveyor, and push the container to be inspected to the designated position of the horizontal storage chamber for inspection, which can automatically complete the feeding and conveying work;

[0017] During use, the electric push rod can drive the driving member to move through the conveyor into the interior of the transverse storage cavity, and drive the container to be inspected to move toward the opening of the transverse storage cavity for automatic discharge. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the overall structure of a biosafety cabinet for PCR testing;

[0019] Figure 2 This is a schematic diagram of the side view of a biosafety cabinet for PCR testing.

[0020] Figure 3 This is a schematic diagram of the structure of an electric push rod used in a biosafety cabinet for PCR testing;

[0021] Figure 4 This is a schematic diagram of the internal structure of a longitudinal conveying channel of a biosafety cabinet for PCR testing;

[0022] Figure 5 This is a schematic diagram of the structure of a biosafety cabinet used for PCR testing.

[0023] Numbers in the figure: 1. Safety cabinet; 11. Cabinet top; 12. Inspection assembly; 2. Horizontal storage chamber; 21. First sealing plate; 3. Longitudinal conveying channel; 31. Second sealing plate; 4. Conveyor; 41. Connecting port; 42. Ultraviolet lamp; 5. Drive assembly; 51. Electric push rod; 52. Mounting frame; 53. Drive member; 54. Electric guide rail; 55. Electric guide rail moving end. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0025] Example 1, by Figure 1-5The utility model provides a biological safety cabinet for PCR testing, comprising a safety cabinet body 1, a plurality of horizontal storage cavities 2 being evenly distributed inside the safety cabinet body 1, a longitudinal conveying channel 3 being longitudinally arranged inside the safety cabinet body 1, the interior of the longitudinal conveying channel 3 being connected to the interiors of the plurality of horizontal storage cavities 2, an opening being arranged at one end of the longitudinal conveying channel 3, the opening of the longitudinal conveying channel 3 being arranged outside the safety cabinet body 1, a driving component 5 being installed inside the longitudinal conveying channel 3, a conveyor 4 connected to the driving component 5 being movably installed inside the longitudinal conveying channel 3, an ultraviolet lamp 42 being installed inside the conveyor 4, when in use, a container to be tested is placed inside the conveyor 4, and the ultraviolet lamp 42 being installed inside the conveyor 4 can sterilize the air entering the conveyor 4 and the surface of the container, thereby preventing bacteria from entering the interior of the safety cabinet 1.

[0026] In this embodiment, a connection port 41 is formed through one end of the conveyor 4 for connecting to the transverse storage chamber 2 . During use, the container to be inspected can be placed into the conveyor 4 through the connection port 41 .

[0027] In this embodiment, the driving assembly 5 includes an electric guide rail 54, which is fixedly installed on the inner bottom of the longitudinal conveying channel 3. An electric guide rail moving end 55 is provided on the electric guide rail 54, and the electric guide rail moving end 55 is fixedly connected to the conveyor 4. During use, the electric guide rail 54 can drive the electric guide rail moving end 55 and the conveyor 4 to move, so that the connecting port 41 of the conveyor 4 is aligned with one of the horizontal storage cavities 2, and the container to be inspected is transported to the designated position to prevent air from flowing in.

[0028] In this embodiment, the drive assembly 5 further includes a plurality of electric push rods 51, which are fixedly mounted on the outside of the safety cabinet 1 via a mounting bracket 52. The plurality of electric push rods 51 are arranged in a one-to-one correspondence with the plurality of transverse storage cavities 2. The output end of each electric push rod 51 is movably extended into the interior of the corresponding transverse storage cavity 2 and is fixedly connected to a drive member 53. During use, the electric push rod 51 can drive the drive member 53 to move into the connection port 41 of the conveyor 4, and push the container to be inspected to the designated position of the transverse storage cavity 2 for inspection, thereby automatically completing the feeding and conveying work.

[0029] During use, the electric push rod 51 can drive the driving member 53 to move through the conveyor 4 into the interior of the transverse storage chamber 2, driving the container to be inspected to move toward the opening of the transverse storage chamber 2 for automatic discharge.

[0030] In this embodiment, each transverse storage cavity 2 is provided with an opening at one end away from the longitudinal conveying channel 3, and the opening is provided on the outer wall of the safety cabinet 1. The opening part of the transverse storage cavity 2 is installed with a first sealing plate 21 for sealing the opening, which can be lifted and slid. The first sealing plate 21 can be lifted and moved to open and close the opening part of the transverse storage cavity 2.

[0031] In this embodiment, a second sealing plate 31 for sealing the opening is installed in a lifting and sliding manner at the opening of the longitudinal conveying channel 3 . During use, the second sealing plate 31 is lifted and moved to open and close the opening of the longitudinal conveying channel 3 .

[0032] In this embodiment, a cabinet top 11 is installed on the top of the safety cabinet 1, and an inspection component 12 is installed on the lower surface of the cabinet top 11 inside each horizontal storage cavity 2. The inspection component 12 inspects the containers to be inspected inside the horizontal storage cavity 2.

[0033] Working principle:

[0034] During use, the container to be inspected is placed inside the conveyor 4 , and the ultraviolet lamp 42 installed inside the conveyor 4 can sterilize the air entering the conveyor 4 and the surface of the container to prevent bacteria from entering the interior of the safety cabinet 1 .

[0035] During use, the electric push rod 51 can drive the driving member 53 to move into the connecting port 41 of the conveyor 4, and push the container to be inspected to the designated position of the transverse storage chamber 2 for inspection, which can automatically complete the feeding and conveying work;

[0036] During use, the electric push rod 51 can drive the driving member 53 to move through the conveyor 4 into the interior of the transverse storage chamber 2, driving the container to be inspected to move toward the opening of the transverse storage chamber 2 for automatic discharge.

[0037] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A biosafety cabinet for PCR testing, comprising a safety cabinet body (1), characterized in that: The safety cabinet (1) has a plurality of transverse storage cavities (2) distributed at equal intervals inside. A longitudinal conveying channel (3) is longitudinally arranged inside the safety cabinet (1). The interior of the longitudinal conveying channel (3) is communicated with the interiors of the plurality of transverse storage cavities (2). An opening is arranged at one end of the longitudinal conveying channel (3). The opening of the longitudinal conveying channel (3) is arranged outside the safety cabinet (1). A driving component (5) is installed inside the longitudinal conveying channel (3). A conveyor (4) connected to the driving component (5) is movably installed inside the longitudinal conveying channel (3). An ultraviolet lamp (42) is installed inside the conveyor (4).

2. A biological safety cabinet for PCR testing according to claim 1, characterized in that: The conveyor (4) is used for connecting to one end of the transverse storage chamber (2) and is provided with a connecting port (41).

3. A biological safety cabinet for PCR testing according to claim 2, characterized in that: The driving assembly (5) comprises an electric guide rail (54), the electric guide rail (54) being fixedly mounted on the inner bottom of the longitudinal conveying channel (3), the electric guide rail (54) being provided with an electric guide rail movable end (55), and the electric guide rail movable end (55) being fixedly connected to the conveyor (4).

4. A biological safety cabinet for PCR testing according to claim 3, characterized in that: The driving assembly (5) further comprises a plurality of electric push rods (51), and the plurality of electric push rods (51) are fixedly mounted on the outside of the safety cabinet (1) via a mounting frame (52).

5. A biological safety cabinet for PCR testing according to claim 4, characterized in that: The plurality of electric push rods (51) are arranged in a one-to-one correspondence with the plurality of transverse storage chambers (2), and the output end of each electric push rod (51) movably extends into the interior of the corresponding transverse storage chamber (2) and is fixedly connected to a driving member (53).

6. A biological safety cabinet for PCR testing according to claim 5, characterized in that: Each transverse storage cavity (2) is provided with an opening at one end away from the longitudinal conveying channel (3), and the opening is provided on the outer wall of the safety cabinet (1). A first sealing plate (21) for sealing the opening is installed in a lifting and sliding manner at the opening of the transverse storage cavity (2).

7. A biological safety cabinet for PCR testing according to claim 6, characterized in that: A second sealing plate (31) for sealing the opening is installed in a lifting and sliding manner at the opening of the longitudinal conveying channel (3).

8. A biological safety cabinet for PCR testing according to claim 6, characterized in that: A cabinet top (11) is installed on the top of the safety cabinet body (1), and an inspection component (12) is installed on the lower surface of the cabinet top (11) inside each transverse storage cavity (2).

Citation Information

Patent Citations

  • Biosafety cabinet for PCR detection

    CN210711580U