Accurate extraction equipment for luteolin

Abstract

The utility model discloses accurate luteolin extraction equipment which comprises a plurality of functional units, firstly, raw materials are crushed by a material processing unit through a crushing mechanism, proper particles are screened out through a screening mechanism, and then, an extraction unit uses an ultrasonic-assisted extraction device to extract luteolin. Dissolving of luteolin by a solvent is accelerated through the cavitation effect of ultrasonic waves, then further extraction is conducted through a continuous countercurrent extractor, extracted liquid enters a separation and purification unit, solid impurities are rapidly separated through a high-speed refrigerated centrifuge, an extracting solution is precisely separated and purified through a liquid chromatography system, and the luteolin is obtained. Finally, the luteolin is subjected to final treatment through a filtering and drying unit, a membrane filtering system and a vacuum freeze dryer are combined for use, impurities are removed through ultrafiltration and nanofiltration technologies, and freeze drying is carried out under low-temperature and low-pressure conditions, so that degradation of heat-sensitive substances is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of luteolin extraction equipment, in particular to a luteolin precision extraction equipment. Background Art

[0002] Luteolin is an important plant active ingredient widely used in the pharmaceutical, health care, and food industries. Its extraction process typically involves multiple steps, including raw material crushing, extraction, separation, and purification. Traditional extraction methods often suffer from low extraction efficiency, low yield, and complex operations. To address these challenges, researchers are constantly exploring new extraction equipment and technologies.

[0003] Traditional extraction equipment generally involves first crushing the raw materials through a grinder, then putting the raw materials into a solvent for soaking extraction, and then continuing the extraction under heating conditions. After extraction, the raw materials are filtered through a filter to obtain an extract, and finally concentrated by rotary evaporation. This type of extraction equipment has low extraction yield, easily causes luteolin to degrade, affects its biological activity, and reduces the quality of the extract. In addition, simple crushing often makes it difficult to achieve uniform particle size, resulting in insufficient contact of the materials during the extraction process, further reducing the extraction efficiency. Utility Model Content

[0004] In view of the above-mentioned deficiencies in the prior art, the purpose of the present invention is to provide a precise extraction device for luteolin with high extraction accuracy, excellent quality and high extraction efficiency.

[0005] The technical solution adopted by the present invention to achieve the above-mentioned purpose is: a luteolin precision extraction device, comprising a material processing unit, an extraction unit, a separation and purification unit, and a filtration and drying unit arranged in sequence, wherein the material processing unit comprises a material crushing mechanism and a screening mechanism;

[0006] The extraction unit includes an ultrasonic-assisted extraction device and a continuous countercurrent extractor;

[0007] The separation and purification unit includes a high-speed refrigerated centrifuge and a matching liquid chromatography system;

[0008] The filtration and drying unit includes a membrane filtration system and a vacuum freeze dryer.

[0009] In the above technical solution, the material crushing mechanism includes a crushing box, a crushing roller group, a grinding roller and a drive motor. The crushing box is provided with a crushing chamber and a grinding chamber located at the bottom of the crushing chamber. A storage chamber is further provided between the crushing chamber and the grinding chamber. The crushing chamber, the storage chamber and the grinding chamber are connected in sequence. The crushing roller group is provided in the crushing chamber.

[0010] The grinding chamber adopts a conical structure, and the inner wall of the grinding chamber is provided with a grinding rough surface A;

[0011] The grinding roller adopts a conical structure, and a grinding rough surface B is provided on the outer wall of the grinding roller;

[0012] The grinding roller is rotatably connected to the grinding chamber, and a grinding area is provided between the grinding roller and the grinding chamber, wherein the space of the grinding area decreases from top to bottom;

[0013] The bottom of the crushing box is connected to the grinding chamber and is provided with a discharge port. The crushing box is fixedly connected to the driving motor, and the driving motor is connected to the crushing roller group and the grinding roller in a power connection.

[0014] In the above technical solution, the crushing roller group includes crushing rollers and gears. Two groups of crushing rollers are rotatably connected in the crushing chamber. The gear is fixedly connected to one end of the roller shaft of each group of crushing rollers. The two groups of gears are meshed and connected. The drive motor is connected to the power of one group of the roller shafts, and the grinding roller is connected to the power of one group of the roller shafts through a power transmission component.

[0015] In the above technical solution, the power transmission assembly includes a power input shaft, a worm, and a worm wheel. The top center of the grinding roller is fixedly connected to an upper shaft, the upper shaft is fixedly connected to the worm wheel, the power input shaft is rotatably connected to the crushing box, the power input shaft is matched with the worm wheel and fixedly connected to the worm, the worm is meshed with the worm wheel, one end of the power input shaft passes through the crushing box, and the power input shaft is located in the external area and is powered by a group of roller shafts of the crushing rollers through a chain transmission assembly.

[0016] In the above technical solution, the storage chamber is fixedly connected to a center platform via multiple sets of connecting columns, the upper shaft is rotatably connected to the center platform, and the center platform is also fixedly connected to a cover shell, and the worm wheel and the worm are located inside the cover shell.

[0017] In the above technical solution, a lower shaft is fixedly connected to the bottom center of the grinding roller, a support platform is fixedly connected to the bottom of the crushing box corresponding to the discharge port, and the lower shaft is rotatably connected to the support platform.

[0018] Beneficial effects of the utility model:

[0019] 1. The use of ultrasonic-assisted extraction and continuous countercurrent extraction technology can significantly improve the extraction rate and efficiency of luteolin and reduce extraction time. The high-speed refrigerated centrifuge combined with the liquid chromatography system can achieve efficient separation and purification. Vacuum freeze-drying technology is then used to remove water at low temperatures, effectively avoiding the degradation of heat-sensitive components and ensuring the biological activity and quality of the extract. Therefore, this equipment can achieve precise extraction of luteolin with excellent extraction quality.

[0020] 2. Through the provided material crushing mechanism, the raw materials can be crushed first and then ground, so that the raw materials can be effectively refined, the surface area of ​​the materials can be increased, and the leaching efficiency of the subsequent extract can be improved. In addition, the conical design of the grinding chamber and the grinding roller can form a gradual grinding area during the crushing process, thereby improving the grinding effect and efficiency of the materials. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the structure of the utility model;

[0022] Figure 2 This is a schematic structural diagram of the material crushing mechanism in the present utility model;

[0023] Figure 3 This is a structural diagram of the material crushing mechanism of the present invention from another perspective;

[0024] Figure 4 This is a schematic diagram of the internal structure of the crushing chamber in the utility model;

[0025] Figure 5 This is a schematic structural diagram of the crushing roller group in the utility model;

[0026] Figure 6 This is a schematic diagram of the internal structure of the grinding chamber in the utility model;

[0027] Figure 7 This is a schematic diagram of the installation structure of the grinding roller in the utility model.

[0028] In the figure: 100 material crushing mechanism, 200 screening mechanism, 300 ultrasonic-assisted extraction device, 400 continuous countercurrent extractor, 500 high-speed refrigerated centrifuge, 600 liquid chromatography system, 700 membrane filtration system, 800 vacuum freeze dryer, 101 crushing box, 102 crushing roller group, 103 grinding roller, 104 driving motor, 105 crushing chamber, 106 grinding chamber, 107 storage chamber, 108 crushing roller, 109 gear, 110 discharge port, 111 grinding rough surface A, 112 grinding rough surface B, 113 upper shaft, 114 lower shaft, 115 connecting column, 116 center platform, 117 support platform, 118 power input shaft, 119 worm, 120 worm gear, 121 chain transmission assembly, 122 cover. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0030] See also Figure 1 A luteolin precision extraction device includes a material processing unit, an extraction unit, a separation and purification unit, and a filtration and drying unit arranged in sequence, wherein the material processing unit includes a material crushing mechanism 100 and a screening mechanism 200, that is, the raw material is crushed by the material crushing mechanism 100, and then the crushed raw material is screened by the screening mechanism 200 to screen out particles that meet the requirements, and the extraction unit includes an ultrasonic assisted extraction device 300 and a continuous countercurrent extractor 400, that is, the screened particles can be put into the extraction tank, and the cavitation effect of the ultrasonic wave is used to accelerate the dissolution and diffusion of the luteolin by the solvent, thereby improving the extraction efficiency and yield, and then further extraction is carried out by the continuous countercurrent extractor 400, and after extraction, it enters the separation and purification unit, and the separation and purification unit here includes a high-speed refrigerated centrifuge 500 and a continuous countercurrent extractor 400. and a matching liquid chromatography system 600, that is, a high-speed refrigerated centrifuge 500 is used to ensure rapid and effective separation of solid impurities, and the liquid chromatography system 600 is used to precisely separate and purify the extract to separate high-purity luteolin, and finally the extract is subjected to final processing by a filtration and drying unit. The filtration and drying unit includes a membrane filtration system 700 and a vacuum freeze dryer 800, that is, the separated liquid is further removed by combining ultrafiltration and nanofiltration technology to further remove impurities and improve the purity of luteolin. The purified luteolin solution is then freeze-dried at low temperature and low pressure to obtain high-purity luteolin powder, avoiding the degradation of heat-sensitive substances. Through the above process, the degradation of heat-sensitive components can be effectively avoided, the biological activity and quality of the extract can be ensured, the precise extraction of luteolin can be achieved, and the quality of the extraction is guaranteed to be excellent.

[0031] See also Figure 2 —7. This embodiment further provides a material crushing mechanism 100:

[0032] The material crushing mechanism 100 includes a crushing box 101, a crushing roller group 102, a grinding roller 103 and a drive motor 104. A crushing chamber 105 and a grinding chamber 106 located at the bottom of the crushing chamber 105 are provided inside the crushing box 101. A storage chamber 107 is further provided between the crushing chamber 105 and the grinding chamber 106. The crushing chamber 105, the storage chamber 107 and the grinding chamber 106 are connected in sequence. A crushing roller group 102 is provided in the crushing chamber 105. The crushing roller group 102 includes a crushing roller 108 and a gear 109. That is, two groups of crushing rollers 108 are rotatably connected in the crushing chamber 105. A gear 109 is fixedly connected to one end of the roller shaft of each group of crushing rollers 108, and the two groups of gears 109 are meshed and connected.

[0033] The bottom of the crushing box 101 is connected to the grinding chamber 106 and is provided with a discharge port 110;

[0034] In addition, the grinding chamber 106 adopts a conical structure, and the inner wall of the grinding chamber 106 is provided with a grinding rough surface A111, while the grinding roller 103 adopts a conical structure, and the outer wall of the grinding roller 103 is provided with a grinding rough surface B112. The grinding roller 103 is rotatably connected to the grinding chamber 106. Specifically, the top center of the grinding roller 103 is fixedly connected to an upper shaft 113, and the bottom center of the grinding roller 103 is fixedly connected to a lower shaft 114. The interior of the storage chamber 107 is fixedly connected to a center platform 116 through multiple groups of connecting columns 115. The upper shaft 113 is rotatably connected to the center platform 116. The bottom of the crushing box 101 is fixedly connected to a support platform 117 corresponding to the discharge port, and the lower shaft 114 is rotatably connected to the support platform 117. A grinding area is provided between the grinding roller 103 and the grinding chamber 106, and the space in the grinding area decreases from top to bottom.

[0035] Furthermore, a driving motor 104 is fixedly connected to the crushing box 101, and the driving motor 104 is connected to one set of rollers by power, while the grinding roller 103 is connected to one set of rollers by power transmission components;

[0036] More specifically, the power transmission assembly includes a power input shaft 118, a worm 119, and a worm wheel 120. The upper shaft 113 is fixedly connected to the worm wheel 120. The power input shaft 118 is rotatably connected to the crushing box 101. The worm wheel 120 on the power input shaft 118 is fixedly connected to the worm 119. The worm 119 is meshed with the worm wheel 120. One end of the power input shaft 118 passes through the crushing box 101. The power input shaft 118 is located in the external area and is connected to the roller shaft of a group of crushing rollers 108 through a chain transmission assembly 121 to achieve power connection. In addition, a cover 122 is also fixedly connected to the center platform 116. The worm wheel 120 and the worm 119 are located inside the cover 122. The cover 122 protects the worm 119 and the worm wheel 120.

[0037] In summary, the raw materials can be put into the crushing chamber 105, and the two sets of crushing rollers 108 can be driven to rotate by the driving motor 104. The raw materials are crushed by the crushing rollers 108, and the crushed raw materials enter the storage chamber 107. Then, under the action of gravity, the raw materials gradually enter the grinding area. At this time, the driving motor 104 also drives the grinding roller 103 to rotate continuously. Under the action of the grinding rough surface A111 and the grinding rough surface B112, the crushed raw materials are ground, and the ground fine particles are discharged through the discharge port 110. Such a structure can effectively refine the raw materials, increase the surface area of ​​the materials, and improve the leaching efficiency of subsequent extracts. In addition, the conical design of the grinding chamber 106 and the grinding roller 103 can form a gradual grinding area during the crushing process, thereby improving the grinding effect and efficiency of the materials.

[0038] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the present invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the present invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be encompassed within the present invention. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

[0039] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. A luteolin precision extraction device, comprising a material processing unit, an extraction unit, a separation and purification unit, and a filtration and drying unit arranged in sequence, characterized in that: The material processing unit comprises a material crushing mechanism (100) and a screening mechanism (200); The extraction unit comprises an ultrasonic-assisted extraction device (300) and a continuous countercurrent extractor (400); The separation and purification unit includes a high-speed refrigerated centrifuge (500) and a matching liquid chromatography system (600); The filtration and drying unit includes a membrane filtration system (700) and a vacuum freeze dryer (800).

2. The luteolin precision extraction device according to claim 1, characterized in that: The material crushing mechanism (100) comprises a crushing box (101), a crushing roller group (102), a grinding roller (103) and a driving motor (104); a crushing chamber (105) and a grinding chamber (106) located at the bottom of the crushing chamber (105) are provided inside the crushing box (101); a storage chamber (107) is provided between the crushing chamber (105) and the grinding chamber (106); the crushing chamber (105), the storage chamber (107) and the grinding chamber (106) are connected in sequence; and the crushing roller group (102) is provided inside the crushing chamber (105); The grinding chamber (106) adopts a conical structure, and the inner wall of the grinding chamber (106) is provided with a grinding rough surface A (111); The grinding roller (103) has a conical structure, and a grinding rough surface B (112) is provided on the outer wall of the grinding roller (103); The grinding roller (103) is rotatably connected to the grinding chamber (106), and a grinding area is provided between the grinding roller (103) and the grinding chamber (106), wherein the space of the grinding area decreases from top to bottom; The bottom of the crushing box (101) is connected to the grinding chamber (106) and is provided with a discharge port (110). The driving motor (104) is fixedly connected to the crushing box (101), and the driving motor (104) is power-connected to the crushing roller group (102) and the grinding roller (103).

3. The luteolin precision extraction device according to claim 2, characterized in that: The crushing roller group (102) includes crushing rollers (108) and gears (109). Two groups of crushing rollers (108) are rotatably connected in the crushing chamber (105). The gear (109) is fixedly connected to one end of the roller shaft of each group of crushing rollers (108). The two groups of gears (109) are meshed and connected. The driving motor (104) is dynamically connected to the roller shaft of one group of crushing rollers (108). The grinding roller (103) is dynamically connected to one group of roller shafts via a power transmission component.

4. The luteolin precision extraction device according to claim 3, characterized in that: The power transmission assembly includes a power input shaft (118), a worm (119), and a worm wheel (120); the top center of the grinding roller (103) is fixedly connected to an upper shaft (113); the upper shaft (113) is fixedly connected to the worm wheel (120); the power input shaft (118) is rotatably connected to the crushing box (101); the power input shaft (118) is fixedly connected to the worm wheel (120) in a manner matching the worm wheel (120); the worm (119) is meshedly connected to the worm wheel (120); one end of the power input shaft (118) passes through the crushing box (101); the power input shaft (118) is located in an external area and is power-connected to a group of roller shafts of the crushing rollers (108) through a chain transmission assembly (121).

5. The luteolin precision extraction device according to claim 4, characterized in that: The storage chamber (107) is fixedly connected to a center platform (116) via multiple groups of connecting columns (115). The upper shaft (113) is rotatably connected to the center platform (116). The center platform (116) is also fixedly connected to a cover (122). The worm wheel (120) and the worm (119) are located inside the cover (122).

6. The luteolin precision extraction device according to claim 5, characterized in that: The bottom center of the grinding roller (103) is fixedly connected to a lower shaft (114), and the bottom of the crushing box (101) is fixedly connected to a support platform (117) corresponding to the discharge port (110), and the lower shaft (114) is rotatably connected to the support platform (117).

Images