Swing device for cell multiplication culture

By introducing adjustment and fixing devices into the swing device, the low efficiency problem caused by the small placement surface of the traditional swing machine is solved, and multiple containers can be placed and swung stably at the same time, thereby improving the efficiency of cell expansion culture and experimental accuracy.

CN223329324UActive Publication Date: 2025-09-12SHENZHEN QIZHI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422500806.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-16
Publication Date
2025-09-12
Estimated Expiration
2034-10-16

AI Technical Summary

Technical Problem

The placement surface of traditional swing machines is small, which requires workers to constantly stop the machine to replace containers, reducing the efficiency of cell expansion and culture.

Method used

A swinging device including an adjusting device and a fixing device is designed. The adjusting device realizes the placement of multiple containers through a slot and a plug-in rod structure, and the fixing device realizes the clamping of containers of different sizes through a threaded hole and a driving rod structure to ensure the stability of the container during the swinging process.

Benefits of technology

The practicability and stability of the swing device are improved, damage to the container due to collision or displacement is avoided, and the accuracy of the experimental results and the reliability of the production process are enhanced.

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Abstract

The utility model relates to the technical field of cell multiplication culture, in particular to a swinging device for cell multiplication culture. The device comprises a swinging machine, an adjusting device is arranged on the surface of the swinging machine, the adjusting device comprises a fixing frame, the fixing frame is fixedly connected with the surface of the swinging machine, the surface of the fixing frame is in sliding connection with a plurality of placing discs, a plurality of inserting grooves are formed in the surface of the fixing frame, and the inserting grooves are connected with the placing discs in a sliding mode. And four arc-shaped blocks are fixedly connected to the surface of the containing disc, inserting rods are slidably inserted into the arc-shaped blocks, and the inserting rods are slidably connected with the inner surfaces of the inserting grooves. The problems that when a worker needs to place a plurality of containers on a swing machine for cell multiplication culture, the placement surface of a traditional swing machine is relatively small, so that the worker can only place one container to perform a test and then perform a test of a next container after the test is completed are solved; and a worker needs to continuously shut down to replace the container, so that the efficiency of cell multiplication culture is greatly reduced.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell expansion and culture, in particular to a swing device for cell expansion and culture. Background Art

[0002] Cell expansion culture is an important biotechnology method that provides a large amount of cell materials for research in various biological fields. When performing cell expansion culture, the culture medium and cells are usually placed in a container and shaken to mix. A swing device is used during shaking, and the container containing the cell solution is placed on the device and shaken.

[0003] A Chinese patent application CN202023097660.6 discloses a shaking device for cell expansion culture. The key points of its technical solution are: the utility model uses a circular swing in the vertical direction to swing the culture bag in the tray, so that the liquid in the culture bag is mixed in multiple directions with the help of its own gravity and swinging force, effectively solving the problems of poor mixing effect of the culture solution and low dissolved oxygen content in the culture solution in single horizontal shaking.

[0004] With respect to the above-mentioned and existing related technologies, the inventors believe that the following defects often exist: when workers need to place multiple containers on an oscillating machine for cell expansion and culture, due to the small placement surface of traditional oscillating machines, workers can only place one container for testing before proceeding to the next container. This causes workers to constantly stop the machine to change containers, which greatly reduces the efficiency of cell expansion and culture. Therefore, to address the above-mentioned problems, an oscillating device for cell expansion and culture is proposed. Utility Model Content

[0005] The purpose of the present utility model is to solve the problem in the prior art that when workers need to place multiple containers on an oscillating machine for cell expansion and culture, due to the small placement surface of the traditional oscillating machine, workers can only place one container for testing before testing the next container, resulting in the workers having to constantly stop the machine to change containers, which greatly reduces the efficiency of cell expansion and culture. The utility model proposes an oscillating device for cell expansion and culture.

[0006] In order to achieve the above-mentioned purpose, the present invention adopts the following technical solution: a swinging device for cell expansion and culture, comprising a swinging machine, an adjusting device provided on the surface of the swinging machine, the adjusting device comprising a fixing frame, the fixing frame being fixedly connected to the surface of the swinging machine, a plurality of placement plates being slidably connected to the surface of the fixing frame, a plurality of slots being provided on the surface of the placement plates, four arc-shaped blocks being fixedly connected to the surface of the placement plates, an insertion rod being slidably inserted in the arc-shaped block, the insertion rod being slidably connected to the inner surface of the slot, and one end of the insertion rod being fixedly connected to an arc plate.

[0007] The above components achieve the following effects: by providing an adjustment device, multiple containers can be placed on the swing machine for swinging, thereby avoiding the situation where workers need to place multiple containers on the swing machine for cell expansion and culture. Due to the small placement surface of the traditional swing machine, workers can only place one container for testing before proceeding to the next container, resulting in workers having to constantly stop the machine to replace containers, which greatly reduces the efficiency of cell expansion and culture. The practicality of the device is improved. At the same time, slots are provided on the fixed frame to adjust the height of the placement tray to accommodate containers of different heights.

[0008] Preferably, the arc surface of the insert rod is sleeved with a spring, and both ends of the spring are fixedly connected to the arc block and the arc plate respectively.

[0009] The effect achieved by the above components is: pulling the arc plate drives the insertion rod to slide backward on the inner surface of the slot until the insertion rod is away from the inner surface of the slot. At this time, the placement plate is pushed to slide on the surface of the fixed frame. When the staff finds the appropriate position and the insertion rod is aligned with the slot, the elastic force of the spring drives the insertion rod to be inserted into the inner surface of the slot, reducing the operation steps of the staff manually pushing the insertion rod into the inner surface of the slot, thereby improving the convenience of the device.

[0010] Preferably, one side of the arc block is fixedly connected to a threaded rod, and the arc surface of the threaded rod is threadedly connected to a baffle.

[0011] The effect achieved by the above components is: to prevent the staff from pulling the insertion rod away from the inner surface of the slot and pushing the placement plate to slide on the surface of the fixing frame, where the elastic force of the spring drives the curved plate to move forward, and the curved plate drives the surface of the insertion rod fixing frame to rub and collide, thereby damaging the insertion rod parts.

[0012] Preferably, one side of the arc block is fixedly connected to a round rod, the arc plate is slidably connected to the arc surface of the round rod, and one end of the round rod is fixedly connected to a stopper.

[0013] The effect achieved by the above components is to prevent the staff from pulling the curved plate with too much force, which causes the curved plate to slide too much and slide out of the arc surface of the round rod.

[0014] Preferably, a fixing device is provided on the surface of the placement plate, and the fixing device includes two threaded holes, both of which are opened on the surface of the placement plate, and the inner surfaces of the threaded holes are threadedly connected to a driving rod, one end of the driving rod is fixedly connected to a turning handle, and the end of the driving rod away from the turning handle is rotatably connected to a clamping plate.

[0015] The effect achieved by the above components is: by setting up a fixing device, the effect of clamping containers of different sizes is achieved, which avoids the situation where the staff places the container in the placement tray and uses the swing machine to swing it, because some tests require the swinging speed to be too fast, so that the container will constantly collide with the placement tray in the placement tray, causing the glass container to break or be damaged, resulting in test failure and waste of resources. At the same time, it ensures that the position of the container is fixed during the swinging process and will not be displaced or tipped over due to the inertia of the swing or external force interference, thereby achieving stable and regular swinging action, which is conducive to improving the accuracy of the experimental results and the reliability of the production process.

[0016] Preferably, a limiting rod is slidably inserted into the placement tray, and one end of the limiting rod is fixedly connected to the clamping plate.

[0017] The effect achieved by the above components is: avoiding the situation where the clamping plate rotates with the rotation of the driving rod when the staff rotates the handle to drive the driving rod to rotate, thereby improving the stability of the device.

[0018] Preferably, a non-slip pad is fixedly connected to the surface of the card plate, and the material of the non-slip pad is rubber.

[0019] The aforementioned components achieve the following: The anti-slip pad is made of rubber, which has a high coefficient of friction. When used to clamp a container, it creates strong friction with the container surface, preventing it from sliding or shifting during the swinging process. Even at high speeds or under external interference, the container's position remains stable, improving the reliability of the swinging operation.

[0020] In summary, the beneficial effects of the present invention are as follows:

[0021] 1. In the present invention, by providing an adjustment device, the effect of placing multiple containers on the swing machine for swinging is achieved, avoiding the situation where workers need to place multiple containers on the swing machine for cell expansion and culture. Due to the small placement surface of the traditional swing machine, workers can only place one container for testing before testing the next container, resulting in workers having to constantly stop the machine to change containers, which greatly reduces the efficiency of cell expansion and culture. The practicality of the device is improved. At the same time, a slot is provided on the fixed frame to adjust the height of the placement tray, thereby accommodating the placement of containers of different heights.

[0022] 2. In the utility model, by setting a fixing device, the effect of clamping containers of different sizes is achieved, which avoids the situation where the staff places the container in the placement tray and uses the swing machine to swing it, because some tests require the swinging speed to be too fast, so that the container will constantly collide with the placement tray in the placement tray, causing the glass container to break or be damaged, resulting in test failure and waste of resources. At the same time, it ensures that the position of the container is fixed during the swinging process and will not be displaced or tipped over due to the inertia of the swing or external force interference, thereby achieving stable and regular swinging action, which is conducive to improving the accuracy of the experimental results and the reliability of the production process. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0024] Figure 2 This is a schematic structural diagram of the regulating device in the present utility model;

[0025] Figure 3 For this utility model Figure 2 A magnified view of point A;

[0026] Figure 4 It is a partial structural diagram of the regulating device in the utility model;

[0027] Figure 5 This is a schematic structural diagram of the fixing device in the present utility model;

[0028] Figure 6 For this utility model Figure 5 Enlarged view of point B.

[0029] Legend: 1. Swing machine; 2. Adjusting device; 201. Fixing frame; 202. Placement plate; 203. Slot; 204. Insert rod; 205. Arc plate; 206. Spring; 207. Threaded rod; 208. Baffle; 209. Block; 210. Arc block; 211. Round rod; 3. Fixing device; 31. Threaded hole; 32. Drive rod; 33. Turning handle; 34. Clamping plate; 35. Limit rod; 36. Anti-slip pad. DETAILED DESCRIPTION

[0030] Reference Figure 1As shown, the utility model provides a technical solution: an oscillating device for cell expansion and culture, comprising an oscillating machine 1, and an adjusting device 2 is provided on the surface of the oscillating machine 1. By providing the adjusting device 2, the effect of placing multiple containers on the oscillating machine 1 for swinging is achieved, thereby avoiding the situation where workers need to place multiple containers on the oscillating machine 1 for cell expansion and culture. Because the placement surface of the traditional oscillating machine 1 is small, workers can only place one container for testing before conducting the next container test, resulting in the need for workers to constantly stop the machine to replace the container, which greatly reduces the efficiency of cell expansion and culture, thereby improving the practicality of the device. At the same time, a slot 203 is provided on the fixed frame 201, which can adjust the height of the placement tray 202 , so as to adapt to the placement of containers of different heights. A fixing device 3 is provided on the surface of the placement tray 202. By setting the fixing device 3, the effect of clamping containers of different sizes is achieved, which avoids the situation that when the staff places the container in the placement tray 202 and uses the swing machine 1 to swing it, the container will not collide with the placement tray 202 continuously in the placement tray 202 because some tests require the swinging speed to be too fast, resulting in the glass container being broken or damaged, resulting in test failure and waste of resources. At the same time, it ensures that the position of the container is fixed during the swinging process and will not be displaced or tipped over due to the inertia of the swing or external force interference, thereby achieving stable and regular swinging action, which is beneficial to improving the accuracy of the experimental results and the reliability of the production process.

[0031] The specific settings and functions of the adjusting device 2 and the fixing device 3 are described in detail below.

[0032] Reference Figure 2 、 Figure 3 and Figure 4As shown, in this embodiment: the adjustment device 2 includes a fixed frame 201, the fixed frame 201 is fixedly connected to the surface of the swing machine 1, the surface of the fixed frame 201 is slidably connected to a plurality of placement plates 202, the surface of the fixed frame 201 is provided with a plurality of slots 203, the surface of the placement plate 202 is fixedly connected to four arc blocks 210, the arc blocks 210 are slidably inserted with an insertion rod 204, the insertion rod 204 is slidably connected to the inner surface of the slot 203, and one end of the insertion rod 204 is fixedly connected to the arc block 210. The arc surface of the plate 205 and the rod 204 is covered with a spring 206. The two ends of the spring 206 are fixedly connected to the arc block 210 and the arc plate 205 respectively. The arc plate 205 is pulled to drive the rod 204 to slide backward on the inner surface of the slot 203 until the rod 204 is away from the inner surface of the slot 203. At this time, the placement plate 202 is pushed to slide on the surface of the fixed frame 201. When the staff finds a suitable position and the rod 204 is aligned with the slot 203, the elastic force of the spring 206 drives The insertion rod 204 is inserted into the inner surface of the slot 203, which reduces the operation steps of the staff pushing the insertion rod 204 into the inner surface of the slot 203 by hand, and improves the convenience of the device. One side of the arc block 210 is fixedly connected to the threaded rod 207, and the arc surface of the threaded rod 207 is threadedly connected to the baffle 208 to prevent the staff from pulling the insertion rod 204 away from the inner surface of the slot 203 and pushing the placement plate 202 to slide on the surface of the fixed frame 201. The force drives the arc plate 205 to move forward, and the arc plate 205 drives the surface friction and collision of the insertion rod 204 fixing frame 201, thereby damaging the insertion rod 204 parts. One side of the arc block 210 is fixedly connected to the round rod 211, and the arc plate 205 is slidably connected to the arc surface of the round rod 211. One end of the round rod 211 is fixedly connected to a stop block 209 to prevent the staff from pulling the arc plate 205 with too much force, causing the arc plate 205 to slide too much and slide out of the arc surface of the round rod 211.

[0033] Reference Figure 5 and Figure 6Specifically, the fixing device 3 includes two threaded holes 31, both of which are formed on the surface of the placement tray 202. A driving rod 32 is threadedly connected to the inner surface of the threaded hole 31. One end of the driving rod 32 is fixedly connected to a handle 33. The end of the driving rod 32 away from the handle 33 is rotatably connected to a clamping plate 34. A limiting rod 35 is slidably inserted into the placement tray 202. One end of the limiting rod 35 is fixedly connected to the clamping plate 34. This prevents the clamping plate 34 from rotating with the driving rod 32 when the operator rotates the handle 33 to rotate the driving rod 32, thereby improving the stability of the device. The surface of the clamping plate 34 is fixedly connected to an anti-skid pad 36. The anti-skid pad 36 is made of rubber. Rubber has a high friction coefficient. When used to clamp a container, it can generate strong friction with the container surface, ensuring that the container will not easily slide or shift during the swinging process. Even when swinging at high speed or under external interference, the container can maintain a stable position, improving the reliability of the swinging operation.

[0034] Working principle: when the staff needs to place multiple containers on the swing machine 1 for swinging, the placing plate 202 is pushed to slide on the surface of the fixed frame 201, and the placing plate 202 drives the arc block 210 to slide, and the arc block 210 drives the round rod 211 to slide, and the round rod 211 drives the stopper 209 to move, and the arc block 210 drives the threaded rod 207 to move, and the threaded rod 207 drives the baffle 208 to move, and the arc block 210 drives the spring 206 to move, and the spring 206 drives the arc plate 205 to move, and the arc plate 205 drives the insertion rod 204 to move. When the staff finds the position of the appropriate container size, the insertion rod 204 is aligned with the slot 203, and the elastic force of the spring 206 drives the arc plate 205 to move forward, and the arc plate 205 drives the insertion rod 204 to be inserted into the insertion slot. The inner surface of the groove 203 is turned on to start the swinging machine 1. The swinging machine 1 drives the fixed frame 201 to swing, the fixed frame 201 drives the placement plate 202 to swing, and the placement plate 202 drives the container to swing. By setting the adjustment device 2, the effect of placing multiple containers on the swinging machine 1 for swinging is achieved, which avoids the situation where the staff needs to place multiple containers on the swinging machine 1 for cell expansion and culture. Because the placement surface of the traditional swinging machine 1 is small, the staff can only place one container for testing before testing the next container, resulting in the staff needing to constantly stop the machine to replace the container, which greatly reduces the efficiency of cell expansion and culture, thereby improving the practicality of the device. At the same time, a slot 203 is set on the fixed frame 201, and the height of the placement plate 202 can be adjusted to accommodate the placement of containers of different heights.

[0035] When the staff needs to clamp the container in the placement tray 202, after placing the container in the placement tray 202, the handle 33 is rotated to drive the driving rod 32, the driving rod 32 drives the clamping block to move, and the clamping block drives the anti-slip pad 36 to move, and the round rod 211 on the surface of the clamping block slides in the placement tray 202 until the clamping block completely clamps the container. By setting the fixing device 3, the effect of clamping containers of different sizes is achieved, and it is avoided that when the staff places the container in the placement tray 202 and uses the swing machine 1 to swing it, the container will not collide with the placement tray 202 continuously in the placement tray 202 because some tests require too fast a swinging speed, resulting in glass containers breaking and being damaged, resulting in test failure and waste of resources. At the same time, it is ensured that the position of the container is fixed during the swinging process and will not be displaced or tilted due to the inertia of the swinging or external force interference, thereby achieving stable and regular swinging action, which is conducive to improving the accuracy of the experimental results and the reliability of the production process.

[0036] In the description of this utility model, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; mechanical connections, electrical connections; direct connections, indirect connections through an intermediate medium, and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on specific circumstances.

Claims

1. A swing device for cell expansion culture, comprising a swing machine (1), characterized in that: The surface of the swing machine (1) is provided with an adjustment device (2), and the adjustment device (2) comprises a fixed frame (201), the fixed frame (201) is fixedly connected to the surface of the swing machine (1), a plurality of placement plates (202) are slidably connected to the surface of the fixed frame (201), a plurality of slots (203) are opened on the surface of the fixed frame (201), four arc blocks (210) are fixedly connected to the surface of the placement plates (202), an insertion rod (204) is slidably inserted in the arc block (210), the insertion rod (204) is slidably connected to the inner surface of the slot (203), and one end of the insertion rod (204) is fixedly connected to the arc plate (205).

2. The oscillating device for cell expansion and culture according to claim 1, characterized in that: The arc surface of the insert rod (204) is covered with a spring (206), and the two ends of the spring (206) are fixedly connected to the arc block (210) and the arc plate (205) respectively.

3. The oscillating device for cell expansion and culture according to claim 1, characterized in that: A threaded rod (207) is fixedly connected to one side of the arc block (210), and a baffle (208) is threadedly connected to the arc surface of the threaded rod (207).

4. The oscillating device for cell expansion and culture according to claim 1, characterized in that: One side of the arc block (210) is fixedly connected to a round rod (211), the arc plate (205) is slidably connected to the arc surface of the round rod (211), and one end of the round rod (211) is fixedly connected to a stopper (209).

5. The oscillating device for cell expansion and culture according to claim 1, characterized in that: The surface of the placement plate (202) is provided with a fixing device (3), and the fixing device (3) includes two threaded holes (31). The two threaded holes (31) are both opened on the surface of the placement plate (202). The inner surfaces of the threaded holes (31) are threadedly connected to a driving rod (32), one end of the driving rod (32) is fixedly connected to a rotating handle (33), and the end of the driving rod (32) away from the rotating handle (33) is rotatably connected to a clamping plate (34).

6. The oscillating device for cell expansion and culture according to claim 1, characterized in that: A limiting rod (35) is slidably inserted into the placement tray (202), and one end of the limiting rod (35) is fixedly connected to the clamping plate (34).

7. The oscillating device for cell expansion and culture according to claim 6, characterized in that: The surface of the card plate (34) is fixedly connected with an anti-skid pad (36), and the material of the anti-skid pad (36) is rubber.

Citation Information

Patent Citations

  • Shaking device for cell multiplication culture

    CN214167997U