Magnetic bead mixing device

Abstract

The utility model relates to a magnetic bead mixing device which comprises a mixing mechanism and a moving mechanism, the mixing mechanism comprises a mixer and a first driving mechanism, and the mixer is used for covering and pressing a cup opening of a reaction cup; the first driving mechanism is connected with the mixer and is used for driving the mixer to vibrate; the moving mechanism is connected with the uniform mixing mechanism, and the moving mechanism is used for driving the uniform mixing mechanism to move between a first position and a second position; when the uniform mixing mechanism is located at the first position, the uniform mixer covers and abuts against the cup opening of the reaction cup; and when the mixing mechanism is located at the second position, the mixer and the reaction cup are separated and have a preset distance. Therefore, the structure of the whole magnetic bead blending device can be simplified, the cost of the magnetic bead blending device is reduced, the blending effect is effectively improved, and the probability of carrying pollution among projects is reduced.

Description

Technical Field

[0001] The present application relates to the field of chemical analysis technology, and in particular to a magnetic bead mixing device. Background Art

[0002] Magnetic beads are often needed in some detection and analysis equipment. For example, chemiluminescent immunoassay (CLIA) technology uses chemical or bioluminescent systems as indicator systems for antigen-antibody reactions to quantitatively detect antigens or antibodies. Luminescent substances can be directly used as markers for antigens or antibodies, or they can be used in free form in the luminescent reactions of antibodies or antigens labeled with catalysts and adjuvants. The free energy released by the chemiluminescent reaction excites the intermediates, causing them to return from the excited state to the ground state, releasing photons of the same energy level. The photons are measured by the chemical immunoassay instrument to accurately quantify the content of the analyte. Chemiluminescent immunoassay technology combines classical methodology and advanced technology, with outstanding advantages such as high sensitivity, high precision and accuracy, good reagent stability, and a high degree of automation.

[0003] When conducting chemiluminescence immunoassay, the cleaning solution, substrate and magnetic beads in the reaction cup must be mixed first. At present, the mixing methods in related technologies include ultrasonic oscillation mixing and rotation mixing. For the first mixing method, the ultrasonic generator probe is in direct contact with the reaction liquid. The probe needs to be cleaned after each mixing. If the cleaning is not thorough, it will cause carryover contamination between projects. In addition, a large amount of cleaning solution is consumed each time, resulting in a large consumption of cleaning solution and increased customer usage costs. For the second mixing method, a large-volume motion mechanism equipped with a stepper motor is used to drive the reaction cup to rotate to achieve mixing. The instrument structure is huge, the cost is increased, and the stepper motor has a low mixing frequency, which cannot effectively disperse the aggregated magnetic beads, resulting in poor mixing effect. Utility Model Content

[0004] Based on this, the present application provides a magnetic bead mixing device with a simple structure, good mixing effect and the ability to reduce the probability of carryover contamination.

[0005] An embodiment of the present application provides a magnetic bead mixing device, comprising a mixing mechanism and a moving mechanism, the mixing mechanism comprising a mixer and a first driving mechanism, the mixer being used to cover and press against the rim of a reaction cup; the first driving mechanism being connected to the mixer, and being used to drive the mixer to vibrate; the moving mechanism being connected to the mixing mechanism, and being used to drive the mixing mechanism to move between a first position and a second position; when the mixing mechanism is in the first position, the mixer covers and presses against the rim of the reaction cup; when the mixing mechanism is in the second position, the mixer and the reaction cup are separated and have a preset distance.

[0006] In one embodiment, the mixer includes a connecting portion and a pressing portion that are connected to each other, the connecting portion is connected to the first driving mechanism, and the pressing portion is used to cover and press the cup mouth of the reaction cup.

[0007] In one embodiment, the pressing portion includes a pressing block and a recessed portion provided on the pressing block, and the recessed portion is used to cover and press the cup mouth of the reaction cup.

[0008] In one embodiment, the moving mechanism includes a fixed frame, a fixed frame and a second driving mechanism; the movable frame is slidably connected to the fixed frame, and the movable frame is connected to the mixing mechanism; the second driving mechanism is arranged on the fixed frame and connected to the movable frame, and the second driving mechanism is used to drive the movable frame to slide relative to the fixed frame.

[0009] In one embodiment, the moving mechanism further includes a guide rail assembly, which includes a linear guide rail and a slider slidably connected to the linear guide rail; the linear guide rail is arranged on the fixed frame, and the slider is connected to the movable frame.

[0010] In one embodiment, the moving mechanism further includes a reset mechanism, which is connected to the movable frame and the fixed frame, and is used to reset the movable frame so that the mixing mechanism is reset from the second position to the first position.

[0011] In one embodiment, the reset mechanism includes an elastic member, one end of the elastic member is connected to the movable frame, and the other end of the elastic member is connected to the fixed frame.

[0012] In one embodiment, the reset mechanism further includes an optical coupling component, wherein the optical coupling component includes an optical coupling sheet and a photoelectric coupler, wherein the optical coupling sheet is disposed on the movable frame, and the photoelectric coupler is disposed on the fixed frame.

[0013] In one embodiment, the second driving mechanism includes a cam and a driving member; the cam is in contact with the movable frame; the driving member is arranged on the fixed frame, the driving member is connected to the cam, and the driving member is used to drive the cam to rotate to drive the movable frame to slide relative to the fixed frame.

[0014] In one embodiment, the first driving mechanism includes a vibration motor.

[0015] The above-mentioned magnetic bead mixing device includes a mixing mechanism and a moving mechanism for driving the mixing mechanism to move between a first position and a second position. The mixing mechanism includes a mixer and a first driving mechanism. The mixer is used to cover and press the cup mouth of the reaction cup; the first driving mechanism is used to drive the mixer to vibrate. In this way, when mixing, the mixing mechanism can be driven to move to the first position by the moving mechanism. The mixer of the mixing mechanism covers and presses the cup mouth of the reaction cup. The first driving mechanism of the mixing mechanism drives the mixer to vibrate, and the mixer drives the reaction cup to vibrate, thereby achieving mixing. After the mixing is completed, the moving mechanism drives the mixing mechanism to move to the second position, so that the mixing mechanism is separated from the reaction cup and has a preset distance. Compared with the ultrasonic vibration mixing in the related art, during the entire mixing process, the mixer does not directly contact the reaction liquid in the reaction cup, thereby reducing the probability of carrying contamination between projects, greatly reducing the amount of cleaning fluid used, and thus reducing the cost of using the magnetic bead mixing device. Compared with the rotational mixing in the related art, the first driving mechanism directly drives the mixer to vibrate, thereby driving the reaction cup to vibrate and achieve mixing, which can effectively improve the mixing effect. At the same time, it simplifies the structure of the mixing mechanism, thereby simplifying the structure of the entire magnetic bead mixing device and reducing the cost of the magnetic bead mixing device. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic structural diagram of a magnetic bead mixing device provided in one embodiment of the present application.

[0017] Figure 2 This is a schematic diagram of the cross-sectional structure of a magnetic bead mixing device provided in one embodiment of the present application.

[0018] Figure 3 This is a structural schematic diagram of the magnetic bead mixing device provided in one embodiment of the present application from another perspective.

[0019] Figure 4 A schematic diagram of the partial structure of a magnetic bead mixing device provided in one embodiment of the present application.

[0020] Figure 5 This is another partial structural schematic diagram of the magnetic bead mixing device provided in one embodiment of the present application.

[0021] Description of reference numerals:

[0022] 10. Magnetic bead mixing device; 20. Reaction cup;

[0023] 110. Mixing mechanism; 111. Mixer; 1111. Connecting portion; 1112. Pressing portion; 1112a. Pressing block; 1112b. Recessed portion; 112. First driving mechanism; 113. Fixed pressure plate; 120. Moving mechanism; 121. Fixed frame; 122. Movable frame; 123. Second driving mechanism; 1231. Cam; 1232. Driving member; 124. Guide rail assembly; 1241. Linear guide rail; 1242. Slider; 125. Resetting mechanism; 1251. Elastic member; 1252. Optocoupler assembly; 1252a. Optocoupler sheet; 1252b. Photoelectric coupler; 130. Controller. DETAILED DESCRIPTION

[0024] To make the above-mentioned objects, features, and advantages of the present application more clearly understood, the specific embodiments of the present application are described in detail below with reference to the accompanying drawings. The following description sets forth many specific details to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways than those described herein, and those skilled in the art can make similar improvements without violating the scope of the present application. Therefore, the present application is not limited to the specific embodiments disclosed below.

[0025] In the description of this application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing this application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0026] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of technical features indicated. Therefore, a feature specified as "first" or "second" may explicitly or implicitly include at least one of such features. In the description of this application, if the term "plurality" appears, "plurality" means at least two, for example, two, three, etc., unless otherwise specifically defined.

[0027] In this application, unless otherwise specified or limited, the terms "mounted," "connected," "connected," "fixed," etc., should be interpreted broadly. For example, these terms may refer to fixed connections, removable connections, or integration; mechanical connections or electrical connections; direct connections or indirect connections through an intermediary; and internal communication between two components or interaction between two components, unless otherwise specified. Those skilled in the art will understand the specific meanings of these terms in this application based on the specific circumstances.

[0028] In this application, unless otherwise expressly specified or limited, if a first feature is described as being "above" or "below" a second feature, or similar descriptions, this may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Furthermore, when a first feature is described as being "above," "above," or "above" a second feature, it may mean that the first feature is directly above or diagonally above the second feature, or simply means that the first feature is at a higher level than the second feature. When a first feature is described as being "below," "below," or "below" a second feature, it may mean that the first feature is directly below or diagonally below the second feature, or simply means that the first feature is at a lower level than the second feature.

[0029] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be an intermediate element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only embodiment.

[0030] Figure 1 A schematic structural diagram of a magnetic bead mixing device provided in one embodiment of the present application is shown; Figure 2 A schematic cross-sectional structure diagram of a magnetic bead mixing device provided in one embodiment of the present application is shown.

[0031] See Figure 1 and Figure 2The embodiment of the present application provides a magnetic bead mixing device 10, including a mixing mechanism 110 and a moving mechanism 120. The mixing mechanism 110 includes a mixer 111 and a first driving mechanism 112; the mixer 111 is used to cover and press the cup mouth of the reaction cup 20; the first driving mechanism 112 is connected to the mixer 111, and the first driving mechanism 112 is used to drive the mixer 111 to vibrate; the moving mechanism 120 is connected to the mixing mechanism 110, and the moving mechanism 120 is used to drive the mixing mechanism 110 to move between a first position and a second position. When the mixing mechanism 110 is in the first position, the mixer 111 covers and presses the cup mouth of the reaction cup 20; when the mixing mechanism 110 is in the second position, the mixer 111 and the reaction cup 20 are separated and have a preset distance.

[0032] The magnetic bead mixing device 10 provided in an embodiment of the present application includes a mixing mechanism 110 and a moving mechanism 120 for driving the mixing mechanism 110 to move between a first position and a second position. The mixing mechanism 110 includes a mixer 111 and a first driving mechanism 112. The mixer 111 is used to cover and press against the cup mouth of the reaction cup 20; the first driving mechanism 112 is used to drive the mixer 111 to vibrate. In this way, when mixing is performed, the mixing mechanism 110 can be driven by the moving mechanism 120 to move to the first position, the mixer 111 of the mixing mechanism 110 covers and presses against the cup mouth of the reaction cup 20, the first driving mechanism 112 of the mixing mechanism 110 drives the mixer 111 to vibrate, and the mixer 111 drives the reaction cup 20 to vibrate, thereby achieving mixing; after the mixing is completed, the moving mechanism 120 drives the mixing mechanism 110 to move to the second position, so that the mixing mechanism 110 is separated from the reaction cup 20 and has a preset distance. Compared to ultrasonic oscillation mixing in related art, during the entire mixing process, the mixer 111 does not directly contact the reaction liquid in the reaction cup 20, thereby reducing the probability of carryover contamination between projects, greatly reducing the amount of cleaning fluid used, and thus reducing the cost of using the magnetic bead mixing device 10. Compared to the rotational mixing in related art, the first drive mechanism 112 directly drives the mixer 111 to vibrate, thereby driving the reaction cup 20 to vibrate and achieve mixing, which can effectively improve the mixing effect. At the same time, it simplifies the structure of the mixing mechanism 110, thereby simplifying the structure of the entire magnetic bead mixing device 10 and reducing the cost of the magnetic bead mixing device 10.

[0033] like Figure 1 and Figure 2 As shown, in one embodiment, the mixer 111 includes a connecting portion 1111 and a pressing portion 1112 that are connected to each other. The connecting portion 1111 is connected to the first driving mechanism 112 , and the pressing portion 1112 is used to cover and press the cup mouth of the reaction cup 20 .

[0034] Thus, the connection portion 1111 facilitates the connection between the mixer 111 and the first driving mechanism 112 , and the pressing portion 1112 facilitates the mixer 111 to cover and press the mouth of the reaction cup 20 , thereby facilitating mixing and improving the mixing effect.

[0035] like Figure 2 As shown, in one embodiment, the pressing portion 1112 includes a pressing block 1112 a and a recessed portion 1112 b disposed on the pressing block 1112 a . The recessed portion 1112 b is used to cover and press the cup mouth of the reaction cup 20 .

[0036] It is understandable that the recessed portion 1112b may be a blind hole provided on the pressing block 1112a, and the cross-sectional shape of the recessed portion 1112b is adapted to the shape of the mouth of the reaction cup 20; specifically, the cross-sectional shape of the recessed portion 1112b is substantially rectangular.

[0037] Therefore, when mixing is performed, the pressing portion 1112 can cover and press the cup mouth of the reaction cup 20 through the recessed portion 1112b, thereby ensuring that the pressing portion 1112 always covers and presses the cup mouth of the reaction cup 20 during the mixing process, so as to perform mixing and improve the mixing effect.

[0038] like Figure 1 、 Figure 2 As shown, in one embodiment, the moving mechanism 120 includes a fixed frame 121, a movable frame 122 and a second driving mechanism 123; the movable frame 122 is slidably connected to the fixed frame 121, and the movable frame 122 is connected to the mixing mechanism 110; the second driving mechanism 123 is arranged on the fixed frame 121 and connected to the movable frame 122, and the second driving mechanism 123 is used to drive the movable frame 122 to slide relative to the fixed frame 121.

[0039] Thus, the second driving mechanism 123 drives the movable frame 122 to slide relative to the fixed frame 121, and the movable frame 122 drives the mixing mechanism 110 to move, so that the mixing mechanism 110 moves between the first position and the second position, thereby improving the working efficiency of the magnetic bead mixing device 10.

[0040] like Figure 2 、 Figure 4 As shown, in one embodiment, the moving mechanism 120 further includes a guide rail assembly 124, which includes a linear guide rail 1241 and a slider 1242 slidably connected to the linear guide rail 1241; the linear guide rail 1241 is set on the fixed frame 121, and the slider 1242 is connected to the movable frame 122.

[0041] Therefore, the guide rail assembly 124 can ensure that the movable frame 122 moves on a fixed straight line track relative to the fixed frame 121, so that the mixing mechanism 110 can be easily driven to move between the first position and the second position, making it convenient for the mixer 111 of the mixing mechanism 110 to move away from or cover and press against the cup mouth of the reaction cup 20, thereby improving the working efficiency of the magnetic bead mixing device 10.

[0042] like Figure 2 、 Figure 3 As shown, in one embodiment, the moving mechanism 120 further includes a reset mechanism 125, which connects the movable frame 122 and the fixed frame 121. The reset mechanism 125 is used to reset the movable frame 122 so that the mixing mechanism 110 is reset from the second position to the first position.

[0043] Therefore, by setting up the reset mechanism 125, the movable frame 122 can be easily reset, and the mixing mechanism 110 can be reset from the second position to the first position. The mixer 111 of the mixing mechanism 110 covers and presses against the cup mouth of the reaction cup 20 to perform mixing, thereby improving the working efficiency of the magnetic bead mixing device 10.

[0044] like Figure 3 As shown, in one embodiment, the reset mechanism 125 includes an elastic member 1251, one end of the elastic member 1251 is connected to the movable frame 122, and the other end of the elastic member 1251 is connected to the fixed frame 121. Specifically, the elastic member 1251 can be a tension spring.

[0045] Therefore, when the second driving mechanism 123 drives the movable frame 122 to slide relative to the fixed frame 121, driving the mixing mechanism 110 to move to the second position, the tension spring is stretched and the tension spring stores elastic potential energy; when the second driving mechanism 123 drives the movable frame 122 to slide relative to the fixed frame 121, driving the mixing mechanism 110 to move toward the first position, the tension spring rebounds, allowing the movable frame 122 to quickly reset, thereby allowing the mixing mechanism 110 to quickly move to the first position, thereby improving the working efficiency of the magnetic bead mixing device 10.

[0046] like Figure 2 、 Figure 3 As shown, in one embodiment, the reset mechanism 125 further includes an optical coupling component 1252 , and the optical coupling component 1252 includes an optical coupling piece 1252 a and a photoelectric coupler 1252 b . The optical coupling piece 1252 a is disposed on the movable frame 122 , and the photoelectric coupler 1252 b is disposed on the fixed frame 121 .

[0047] Therefore, through the cooperation of the optical coupling piece 1252a and the photoelectric coupler 1252b, the position of the movable frame 122 can be easily checked and reset, thereby facilitating the inspection of the position of the mixing mechanism 110 to improve the reliability of the magnetic bead mixing device 10.

[0048] like Figures 2 to 4 As shown, in one embodiment, the second driving mechanism 123 includes a cam 1231 and a driving member 1232, the cam 1231 is in contact with the movable frame 122; the driving member 1232 is disposed on the fixed frame 121, the driving member 1232 is connected to the cam 1231, and the driving member 1232 is used to drive the cam 1231 to rotate, so as to drive the movable frame 122 to slide relative to the fixed frame 121.

[0049] Thus, the cam 1231 is driven to rotate by the driving member 1232. When the protruding part of the cam 1231 gradually contacts the movable frame 122, the movable frame 122 is driven to slide relative to the fixed frame 121, thereby driving the mixing mechanism 110 to move to the second position. When the most convex point of the protruding part of the cam 1231 contacts the movable frame 122, the movable frame 122 stops moving and the mixing mechanism 110 moves to the second position. When the protruding part of the cam 1231 gradually moves away from the movable frame 122, under the action of the gravity of the mixing mechanism 110 and the movable frame 122 itself, the movable frame 122 slides relative to the fixed frame 121, driving the mixing mechanism 110 to move from the second position to the first position. When the photoelectric coupler 1252b detects the optical coupling piece 1252a, the movable frame 122 is reset to return to the initial position, and the mixing mechanism 110 reaches the first position.

[0050] It is understandable that the driving member 1232 may be a motor, specifically, the driving member 1232 may be a stepping motor.

[0051] In another embodiment, the second driving mechanism 123 may be a linear driving mechanism, such as a ball screw mechanism, a hydraulic cylinder, a pneumatic cylinder, etc.

[0052] In one embodiment, the first driving mechanism 112 includes a vibration motor. In a specific example, the first driving mechanism 112 includes a magnetic levitation motor.

[0053] The vibration frequency of the vibration motor, especially the magnetic levitation motor, is relatively high. Therefore, by making the first driving mechanism 112 include the vibration motor and the magnetic levitation motor, the vibration frequency of the mixer 111 can be effectively increased, thereby increasing the vibration frequency of the reaction cup 20 and further improving the mixing effect.

[0054] like Figure 1 、 Figure 3 As shown, in one embodiment, the first driving mechanism 112 is fixed to the movable frame 122 via a fixed pressure plate 113 . The fixed pressure plate 113 is covered outside the first driving mechanism 112 and is fixedly connected to the movable frame 122 .

[0055] Therefore, the first driving mechanism 112 can be conveniently fixed on the movable frame 122 , thereby fixing the mixing mechanism 110 on the movable frame 122 .

[0056] like Figure 5 As shown, in one embodiment, a controller 130 is further included. The controller 130 can be set on the movable frame 122 and electrically connected to the first driving mechanism 112, the photoelectric coupler 1252b and the second driving mechanism 123. Specifically, the controller 130 can include a driving circuit board, etc.

[0057] Thus, the operation of the first driving mechanism 112 and the second driving mechanism 123 can be controlled by the controller 130. When the photoelectric coupler 1252b detects the optical coupling piece 1252a, the controller 130 controls the operation of the first driving mechanism 112 to perform mixing. In this way, the automatic control of the magnetic bead mixing device 10 can be realized, and the working efficiency of the magnetic bead mixing device 10 can be improved.

[0058] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0059] The above-described embodiments merely represent several implementation methods of the present application. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that a person of ordinary skill in the art may make various modifications and improvements without departing from the spirit of the present application, and these modifications and improvements fall within the scope of protection of the present application. Therefore, the scope of protection of the present patent application shall be determined by the appended claims.

Claims

1. A magnetic bead mixing device, characterized in that: include: A mixing mechanism, comprising a mixer and a first driving mechanism, wherein the mixer is used to cover and press against the mouth of the reaction cup; The first driving mechanism is connected to the mixer, and the first driving mechanism is used to drive the mixer to vibrate; A moving mechanism is connected to the mixing mechanism, and is used to drive the mixing mechanism to move between a first position and a second position; when the mixing mechanism is in the first position, the mixer covers and presses against the cup mouth of the reaction cup; when the mixing mechanism is in the second position, the mixer and the reaction cup are separated and have a preset distance.

2. The magnetic bead mixing device according to claim 1, characterized in that: The mixer includes a connecting portion and a pressing portion that are connected to each other, the connecting portion is connected to the first driving mechanism, and the pressing portion is used to cover and press the cup mouth of the reaction cup.

3. The magnetic bead mixing device according to claim 2, characterized in that: The pressing portion includes a pressing block and a recessed portion provided on the pressing block, and the recessed portion is used for covering and pressing the cup mouth of the reaction cup.

4. The magnetic bead mixing device according to claim 1, characterized in that: The moving mechanism comprises: Fixed frame; A movable frame is slidably connected to the fixed frame, and the movable frame is connected to the mixing mechanism; A second driving mechanism is provided on the fixed frame and connected to the movable frame, and the second driving mechanism is used for driving the movable frame to slide relative to the fixed frame.

5. The magnetic bead mixing device according to claim 4, characterized in that: The moving mechanism further includes a guide rail assembly, which includes a linear guide rail and a slider slidably connected to the linear guide rail; the linear guide rail is arranged on the fixed frame, and the slider is connected to the movable frame.

6. The magnetic bead mixing device according to claim 4, characterized in that: The moving mechanism further includes a reset mechanism, which is connected to the movable frame and the fixed frame. The reset mechanism is used to reset the movable frame so as to reset the mixing mechanism from the second position to the first position.

7. The magnetic bead mixing device according to claim 6, characterized in that: The reset mechanism includes an elastic member, one end of the elastic member is connected to the movable frame, and the other end of the elastic member is connected to the fixed frame.

8. The magnetic bead mixing device according to claim 6, characterized in that: The reset mechanism further includes an optical coupling component, which includes an optical coupling sheet and a photoelectric coupler. The optical coupling sheet is arranged on the movable frame, and the photoelectric coupler is arranged on the fixed frame.

9. The magnetic bead mixing device according to claim 4, characterized in that: The second driving mechanism comprises: a cam, the cam being in contact with the movable frame; A driving member is provided on the fixed frame, the driving member is connected to the cam, and the driving member is used to drive the cam to rotate, so as to drive the movable frame to slide relative to the fixed frame.

10. The magnetic bead mixing device according to claim 1, characterized in that: The first driving mechanism includes a vibration motor.

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