Disposable ultraviolet flow cell

Abstract

The utility model discloses a disposable ultraviolet flow cell, a cell body is provided with a liquid passing pipe and two optical fiber connectors, and the disposable ultraviolet flow cell is characterized in that the liquid passing pipe is arranged in the left-right direction of the cell body in a penetrating manner, the two optical fiber connectors are symmetrically arranged at the upper end and the lower end of the cell body, the inner sides of the two adjacent optical fiber connectors are respectively provided with a collimating lens, and the two collimating lenses are fixedly arranged on the cell body. The cell body can be replaced for use at a time, the internal sanitation and cleanliness of the cell body are high, the cleaning process in the actual process is reduced, the flow cell can be directly replaced under the condition that residual impurities are not easy to clean, the operation is simple, the operation is practical and convenient, and the requirements of improving the process efficiency are met; one-time replacement of a complete pipeline can be achieved, and replacement is flexible, fast and efficient.

Description

Technical Field

[0001] The utility model relates to an ultraviolet flow cell, which is used for measuring the change of light intensity passing through the flow cell to detect the change of component concentration in a sample and belongs to the technical field of biopharmaceuticals. Background Art

[0002] UV detectors are suitable for detecting organic molecules with UV or visible light absorbing groups, or substances with strong UV or visible light absorption capabilities. Therefore, they are widely used in fields such as biopharmaceuticals, chemical processes, and environmental protection. Their operating principle is as follows: UV light emitted from a specific light source passes through a condenser and cylindrical lens, then enters the flow cell as a parallel beam of a single wavelength. After passing through the detection area, it passes through another cylindrical lens and condenser lens, irradiating the photosensor. The varying concentrations of the sample in the mobile phase cause changes in light intensity, which are converted into changes in photocurrent. After amplification, the light is input into a logarithmic converter or recorder, yielding a spectrum showing changes in sample concentration or optical density.

[0003] However, existing UV flow cells have the following drawbacks: 1) They cannot be directly replaced during the testing process and must be cleaned each time to prevent liquid residue, which is a complex operation; 2) When the UV flow cell is used in conjunction with disposable chromatography, ultrafiltration, or other equipment, the UV flow cell must be retained, making it impossible to completely replace the entire pipeline at once, and the replacement process is cumbersome. Therefore, it is necessary to propose a disposable UV flow cell to improve its performance. Summary of the Invention

[0004] The purpose of the utility model is to solve the above problems and provide a disposable ultraviolet flow cell.

[0005] The technical solution of the utility model is: a disposable ultraviolet flow cell, comprising a cell body, the cell body being provided with a liquid passage tube and two optical fiber connectors, and its characteristics are: the liquid passage tube is arranged through the left and right directions of the cell body; the two optical fiber connectors are symmetrically arranged at the upper and lower ends of the cell body, and collimating lenses are respectively provided on the inner sides of the two adjacent optical fiber connectors, and the two collimating lenses are both fixed on the cell body.

[0006] Furthermore, in the above-mentioned disposable UV flow cell, an optical path for inputting and outputting optical fiber light beams is formed between the two optical fiber connectors.

[0007] Furthermore, in the above-mentioned disposable UV flow cell, the bottom end of the optical fiber connector is provided with an external thread structure, and the external thread structure is adapted to be connected with the internal thread of the cell body.

[0008] Furthermore, in the above-mentioned disposable UV flow cell, a spacer is provided between the optical fiber connector and the collimating lens.

[0009] Furthermore, in the above-mentioned disposable UV flow cell, the two collimating lenses are made of disposable optical plastic injection molding.

[0010] Furthermore, in the above-mentioned disposable UV flow cell, a liquid flow path for filling with solution is formed inside the liquid flow tube.

[0011] Furthermore, in the above-mentioned disposable UV flow cell, two flow path windows are provided at the center of the liquid flow path, which are symmetrical in upper and lower directions, and the flow path windows and the center point of the collimating lens are distributed on the same axis.

[0012] Furthermore, in the above-mentioned disposable UV flow cell, the two flow path windows are cylindrical protruding structures.

[0013] Compared with the existing technology, after adopting the technical solution of the utility model, the internal hygiene and cleanliness of the disposable UV flow cell is high, which reduces the cleaning process in the actual process. When encountering impurities that are difficult to clean, the flow cell can be directly replaced. The operation is simple, practical and convenient, and is more suitable for the needs of improving process efficiency. Moreover, when a collimating lens made of disposable optical plastic is used, the complete pipeline can be replaced at one time, and the replacement is flexible, fast and efficient. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is the main view of the utility model;

[0015] Figure 2 It is a side view of the utility model;

[0016] Figure 3 for Figure 2 Schematic diagram of the cross section along the AA direction.

[0017] The meanings of the reference numerals in the figure are: 1-cell body, 2-liquid passage, 3-optical fiber connector, 4-spacer, 5-collimating lens, 6-flow path window, 7-optical path, 8-liquid flow path. DETAILED DESCRIPTION

[0018] The following further illustrates the technical solution of the present invention with reference to the accompanying drawings to make it easier to understand and grasp. The optical fiber connector 3 and the spacer 4 involved are commonly used by those skilled in the art, and there are no special requirements for them in this case.

[0019] like Figures 1 to 3 As shown, a disposable UV flow cell of the present invention comprises a cell body 1 , wherein the cell body 1 is provided with a liquid passage tube 2 and two optical fiber connectors 3 .

[0020] According to the technical solution of the present utility model, the liquid passage 2 is arranged in the left and right directions of the pool body 1; the two optical fiber connectors 3 are symmetrically arranged at the upper and lower ends of the pool body 1, and an optical path 7 is formed between the two optical fiber connectors 3, which can be used to input and output optical fiber light beams; collimating lenses 5 are respectively provided on the inner sides of the two adjacent optical fiber connectors 3, and the two collimating lenses 5 are both fixed on the pool body 1, and the collimating lenses 5 and the pool body 1 are sealed and fixed by an O-ring to improve the connection tightness between the two.

[0021] Preferably, in the above structure: a liquid flow path 8 is formed inside the liquid passage 2, and the liquid flow path 8 can be used to be filled with a solution.

[0022] Preferably, in the above structure: the bottom end of the optical fiber connector 3 is provided with an external thread structure, which is adapted to connect with the internal thread of the cell body 1. The threaded installation has the advantages of simple structure, easy assembly and disassembly, and reliable connection.

[0023] Preferably, in the above structure: a spacer block 4 is further provided between the optical fiber connector 3 and the collimating lens 5 , and the spacer block 4 is used to provide a protective and concealed horizontal support surface for the collimating lens 5 to improve the installation firmness of the collimating lens 5 .

[0024] Preferably, in the above structure: the two collimating lenses 5 are made of disposable optical plastic injection molding so as to be disposable and replaceable.

[0025] Preferably, in the above structure, two flow path windows 6 are provided at the center of the liquid flow path 8 symmetrically in the vertical direction, and the flow path windows 6 and the center point of the collimating lens 5 are distributed on the same axis.

[0026] Specifically, the two flow path windows 6 are cylindrical protruding structures, and the distance between the two flow path windows 6 is the thickness of the liquid layer to be inspected, that is: the optical path distance between the two flow path windows 6 is the actual optical path of the disposable UV flow cell. The actual optical path length is relatively long, which can improve the sensitivity and resolution of the UV detector. The wider the sample concentration range that the UV detector can detect, the further improve the linear range and response time of the UV detector and other performance indicators, thereby improving the overall UV detection accuracy and efficiency.

[0027] Among the technical solutions of this utility model, the disposable replaceable UV flow cell is the key technology of this case. Figure 3 The focus is on the cell body components. By using disposable optical plastic injection molding to mold the collimating lens 5, the entire flow cell pipeline can be directly replaced. Components such as the fiber connector 3 and the spacer 4 can be conventionally configured by a person skilled in the art based on existing techniques. This application does not require any special requirements for their model selection or combination.

[0028] In this way, by adopting the technical solution of the present invention, under normal working conditions, after the solution forms a liquid flow path 8 and fills the liquid tube 2, the optical fiber is connected to the optical fiber connector 3 on the cell body 1, and the incident optical fiber formed enters the cell body 1. The light beam of the incident optical fiber is collimated and focused by the collimating lens 5 at one end, so that the light beam is parallel light. The parallel light passes through the flow path window 6 and transmits the solution, and the intensity of the light beam is attenuated, thereby measuring the absorbance; finally, the parallel light is converged by another collimating lens 6, and the output optical fiber formed outputs a light signal to the ultraviolet detector, thereby detecting the measured substance and processing and analyzing the data of the corresponding detection results.

[0029] From the above description, it can be found that compared with the existing technology, after adopting the technical solution of the utility model, it can be replaced and used once, which reduces the cleaning process in the actual process. When encountering impurities that are difficult to clean, the circulation pool can be directly replaced. The operation is simple and practical and convenient, which is more suitable for the needs of improving process efficiency; moreover, when a collimating lens made of disposable optical plastic is used, the pool body and the collimating lens can be directly replaced together, thereby realizing a one-time replacement of the complete pipeline, and the replacement is flexible, fast and efficient.

[0030] The above describes the technical solution, working process and implementation effect of the utility model in detail. It should be noted that what is described is only a typical example of the utility model. In addition, the utility model can also have many other specific implementation methods. Any technical solution formed by equivalent replacement or equivalent transformation falls within the scope of protection required by the utility model.

Claims

1. A disposable UV flow cell, comprising a cell body (1), wherein the cell body (1) is provided with a liquid passage tube (2) and two optical fiber connectors (3), characterized in that: The liquid passage tube (2) is arranged to pass through the pool body (1) in the left and right directions. The two optical fiber connectors (3) are symmetrically arranged at the upper and lower ends of the pool body (1). An optical path (7) for inputting and outputting optical fiber light beams is formed between the two optical fiber connectors (3). Collimating lenses (5) are respectively provided on the inner sides of the two adjacent optical fiber connectors (3). The two collimating lenses (5) are both fixed on the pool body (1).

2. The disposable UV flow cell according to claim 1, wherein: A liquid flow path (8) for filling with a solution is formed inside the liquid passage tube (2).

3. The disposable UV flow cell according to claim 2, wherein: Two upper and lower symmetrical flow path windows (6) are provided at the center of the liquid flow path (8), and the flow path windows (6) and the center point of the collimating lens (5) are distributed on the same axis.

4. The disposable UV flow cell according to claim 3, wherein: The two flow path windows (6) are cylindrical protruding structures.

5. The disposable UV flow cell according to claim 1, wherein: The bottom end of the optical fiber connector (3) is provided with an external thread structure, and the external thread structure is adapted to be connected with the internal thread of the cell body (1).

6. The disposable UV flow cell according to claim 1, wherein: A spacer (4) is also provided between the optical fiber connector (3) and the collimating lens (5).

7. The disposable UV flow cell according to claim 1, wherein: The two collimating lenses (5) are made of disposable optical plastic injection molding.

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