Sampling device for mouse nose tissue sample

Abstract

The utility model discloses a mouse nose tissue sample sampling device, which relates to the technical field of biomedical research and comprises an operating table and a cutting mechanism. A nose tissue sample contour is arranged on the operation table; the cutting mechanism comprises a frame and at least one cutting assembly. The four corners of the operation table are each correspondingly provided with a stand column. The frame is located above the operation table and arranged on the stand columns in a sliding mode in the vertical direction. In a natural state, the frame can keep a distance away from the operation table; the cutting assembly is arranged on the frame in a sliding mode in the first direction, and the first direction is parallel to the top face of the operation table and perpendicular to the vertical direction. The lower end of the cutting assembly is provided with a cutting blade. An operator can accurately cut a mouse nose tissue sample, and the injury risk of the operator is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of biomedical research, in particular to a device for collecting rat nasal tissue samples. Background Art

[0002] Rats and mice play a vital role in biomedical research, thanks to their high genetic similarity to humans, robust reproductive capacity, and manageable husbandry. They are widely used in a variety of fields, including disease model construction, genetics research, oncology, neurobiology, immunology, pharmacology, toxicology, and translational medicine. In particular, humanized mouse models developed through gene editing technologies have become powerful tools for studying the mechanisms of human disease and evaluating new therapies, providing unprecedented depth and breadth to medical research.

[0003] In applied research on mice and rats, autopsy sampling is an essential and fundamental technique, playing a crucial role in pathological research and disease diagnosis. Currently, animal pathology autopsy sampling relies primarily on manual labor, which not only requires high operator expertise but also carries potential risks such as personal injury. Utility Model Content

[0004] The purpose of the present invention is to provide a device for collecting rat nasal tissue samples to solve the problems existing in the above-mentioned prior art, so that the operator can accurately cut the rat nasal tissue sample and reduce the risk of injury to the operator.

[0005] To achieve the above purpose, the present invention provides the following solutions:

[0006] The utility model provides a device for obtaining a rat nasal tissue sample, comprising an operating table and a cutting mechanism; a nasal tissue sample outline is provided on the operating table; the cutting mechanism comprises a frame and at least one cutting assembly; a column is provided at each of the four corner positions of the operating table; the frame is located above the operating table and is slidably arranged on each of the columns in a vertical direction; and in a natural state, the frame can maintain a distance from the operating table; the cutting assembly is slidably arranged on the frame in a first direction, the first direction being parallel to the top surface of the operating table and perpendicular to the vertical direction; and a cutting blade is provided at the lower end of the cutting assembly.

[0007] Preferably, the frame includes two oppositely arranged armrest plates and two oppositely arranged slide rods; the two armrest plates and the two slide rods together form a square frame; the slide rod is provided with a sliding groove, and the end of the cutting assembly can slide along the first direction in the sliding groove; the interior of the column has a hollow cavity and a side opening connected to the hollow cavity, and the side opening extends in the vertical direction; the square frame is fixedly provided with an extension part at the position corresponding to each side opening, and the extension part is located in the hollow cavity; a spring is provided in the hollow cavity below the extension part.

[0008] 4. The repairing kit for automotive dents, according to claim 1, wherein a bottom of the foot stand comprises a through-hole, and the two foot pieces comprise two bosses, wherein the bosses comprise a through-hole, a screw bolt, and a nut. The through-hole comprises a screw bolt, and a nut. The through-hole comprises a screw bolt, and a nut. The two foot pieces comprise a through-hole, a screw bolt, and a nut.

[0009] Preferably, a first scale line is provided on the operating table.

[0010] Preferably, a second scale line is provided on the frame, and the second scale line is used to indicate the sliding position of the cutting assembly in the first direction, and the second scale line corresponds to the first scale line one by one.

[0011] Preferably, the operating table includes a bottom support plate and a base; the lower end of the column is fixedly arranged on the bottom support plate; the base is detachably fixedly arranged on the upper end surface of the bottom support plate, and the nasal tissue sample outline is arranged on the base.

[0012] Preferably, a locking member is provided on the slider, and the locking member can lock the relative position between the slider and the sliding groove.

[0013] Preferably, the locking member is a locking bolt; the upper end of the sliding groove rod is provided with a fourth sliding guide hole connected to the sliding groove; the position of the sliding block corresponding to the fourth sliding guide hole is provided with a locking threaded hole, and the threaded end of the locking bolt passes through the fourth sliding guide hole and is threadedly connected in the locking threaded hole.

[0014] Preferably, a knob is fixedly provided on the end of the fastening rod extending out of the second sliding guide hole.

[0015] Preferably, the number of the cutting components is at least two, and the cutting components are arranged in parallel along the first direction.

[0016] Compared with the prior art, the utility model has achieved the following technical effects:

[0017] The mouse nasal tissue sampling device provided by the present invention has a cutting mechanism disposed above an operating table. The cutting mechanism can slide up and down on a column. When cutting a mouse nasal tissue sample, the sample can be fixed at the contour of the nasal tissue sample. By moving the frame up and down, the cutting assembly is driven downward to cut the sample, thereby completing precise cutting of the mouse nasal tissue sample. In addition, the cutting mechanism can maintain a distance from the operating table in a natural state, which can keep the cutting assembly away from the operating table. The entire operation process also reduces contact between the operator and the cutting blade, thereby reducing the risk of injury to the operator.

[0018] Furthermore, a square structure is formed by two armrest plates and two slide rods, which provides a stable frame foundation for the entire device, thereby driving the cutting assembly to move up and down stably; the sliding groove on the slide rod provides a clear sliding path for the cutting assembly, so that the cutting assembly can slide accurately in the first direction; the hollow cavity and side opening inside the column provide activity space for the square frame and the extension part, and the entire frame can be raised and lowered by moving the extension part up and down in the hollow cavity; a spring is arranged in the hollow cavity below the extension part, which can rebound to the top by itself after cutting is completed, making room for the sample below to be taken and placed, and facilitating the next cutting operation.

[0019] Furthermore, the cutting assembly adopts a modular setting to facilitate maintenance and replacement; and after the blade is placed in the shelf slot, it can be fastened by the fastening rods at both ends to ensure the stability of the blade; the slider slides in the sliding slot along the first direction, and at the same time the guide rod slides in the third sliding guide hole, providing dual guidance for the movement of the tool holder, ensuring the stability of the cutting direction.

[0020] Furthermore, the first scale line provides an intuitive measurement standard for the operator. When performing a sampling operation, the position and size of the sample can be accurately determined according to the scale line, thereby precisely controlling the cutting.

[0021] Furthermore, the first scale line on the operating table and the second scale line on the frame cooperate with each other to provide a dual reference for the operator. When performing material collection operations, the two scale lines can be observed at the same time to more accurately determine the position of the cutting component.

[0022] Furthermore, the operating table is divided into two layers: a bottom support plate and a base, providing more stable support for the entire device: the bottom support plate serves as the basic layer, which can bear the weight of the columns and other components, ensuring that the device will not shake or tilt during use; the base can more focused on carrying nasal tissue samples, so that the samples remain stable during the sampling process; different mouse nasal tissue samples have different shapes and sizes, and different bases can be replaced to meet different sample collection needs.

[0023] Furthermore, the locking member can lock the relative position between the slider and the sliding groove after the slider is adjusted to the appropriate position, ensuring that the blade will not change position due to accidental sliding during the cutting process, thereby ensuring the cutting accuracy; the locking member can ensure the position of each cutting and ensure cutting consistency.

[0024] Furthermore, the locking bolt, as a common and reliable fastening element, can provide a strong locking force; quick locking can be achieved by tightening the locking bolt, and the locking operation is simple and convenient; this locking structure is compactly designed, and the locking bolt and related threaded holes, sliding guide holes and other components are integrated on the slide rod and the slider, which does not take up too much space.

[0025] Furthermore, the design of the knob provides a large, easy-to-grip surface, so that the operator can easily rotate the knob with his fingers or palm; the design of the knob enables the operator to more accurately control the degree of rotation of the tightening rod.

[0026] Furthermore, multiple cutting components can cut the mouse nose tissue at the same time, greatly shortening the sampling time; multiple cutting components are arranged in parallel, which can ensure the consistency of each cutting position during cutting; the number and spacing of cutting components can be flexibly adjusted according to different experimental purposes and sample requirements. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0028] Figure 1 This is a schematic diagram of the overall structure of the mouse nasal tissue sample collection device provided by the utility model;

[0029] Figure 2 This is a schematic diagram of the structure of the upright column in the mouse nasal tissue sample collection device provided by the utility model;

[0030] Figure 3 A schematic diagram of the frame and cutting components of the mouse nasal tissue sampling device provided by the present invention;

[0031] Figure 4 This is a schematic diagram of the structure of the slide rod in the mouse nose tissue sample collection device provided by the present invention;

[0032] Figure 5 This is a schematic structural diagram of the cutting assembly in the mouse nasal tissue sample collection device provided by the present invention;

[0033] Figure 6 This is a schematic diagram of the coordinated structure of the cutting assembly and the frame in the mouse nasal tissue sample collection device provided by the present invention.

[0034] In the picture:

[0035] 100- Mouse nasal tissue sampling device;

[0036] 10-operating table; 11-bottom support plate; 12-base; 121-nasal tissue sample outline; 13-first scale line;

[0037] 20-column; 21-side opening; 22-spring; 23-sealing plug;

[0038] 30 - frame; 31 - slide rod; 311 - slide slot; 312 - first slide guide hole; 313 - second slide guide hole; 314 - third slide guide hole; 315 - fourth slide guide hole; 32 - armrest plate; 33 - extension; 34 - second scale line;

[0039] 40-cutting assembly; 41-tool holder; 42-blade; 43-sliding assembly; 431-slider; 432-fastening rod; 433-guide rod; 434-knob; 44-locking bolt. DETAILED DESCRIPTION

[0040] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0041] The purpose of the utility model is to provide a device for collecting rat nasal tissue samples to solve the problems existing in the prior art, so that an operator can accurately cut the rat nasal tissue sample and reduce the risk of injury to the operator.

[0042] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0043] Example 1

[0044] This embodiment provides a device 100 for collecting rat nasal tissue samples. Figures 1 to 6 As shown, the apparatus comprises an operating table 10 and a cutting mechanism; a nasal tissue sample outline 121 is provided on the operating table 10; the cutting mechanism comprises a frame 20 and at least one cutting assembly 40; a column 20 is provided at each of the four corners of the operating table 10; the frame 20 is located above the operating table 10 and is slidably mounted on each column 20 in a vertical direction; and in a natural state, the frame 20 can maintain a distance from the operating table 10; the cutting assembly 40 is slidably mounted on the frame 20 in a first direction, the first direction being parallel to the top surface of the operating table 10 and perpendicular to the vertical direction; and a cutting blade is provided at the lower end of the cutting assembly 40.

[0045] By disposing a cutting mechanism above the operating table 10, the cutting mechanism can slide up and down on the column 20. When cutting a mouse nasal tissue sample, the sample can be fixed at the nasal tissue sample contour 121. By moving the frame 20 up and down, the cutting assembly 40 is driven downward to cut the sample, completing the precise cutting of the mouse nasal tissue sample. Moreover, the cutting mechanism can maintain a distance from the operating table 10 in a natural state, which can keep the cutting assembly 40 away from the operating table 10. The entire operation process also reduces the contact between the operator and the cutting blade, reducing the risk of injury to the operator.

[0046] Specifically, the mouse nasal tissue sampling device 100 provided in this embodiment achieves uniform and smooth nasal tissue sampling, while also enabling rapid and accurate nasal tissue collection. It accurately cuts nasal tissue from both mice and rats, achieving smooth cuts with controllable thickness. When used with multiple cutting assemblies 40, three sections of nasal tissue can be precisely obtained in a single cut, ensuring the integrity of the tissue sample to a certain extent. Furthermore, the operator only needs to press the handrail 32 to complete the tissue segmentation and sampling, effectively protecting the operator from sharp injuries.

[0047] Among them, the relevant structural settings of the operating console 10 are described as follows:

[0048] Specifically, when sampling nasal tissue from rats and mice, the sample is fixed according to the nasal tissue sample outline 121, each blade 42 is mounted on the corresponding blade holder 41, and the knob 434 is rotated clockwise to clamp the blade 42. The sample is then positioned in accordance with the first scale line 13 and the second scale line 34. Both hands are placed on the armrest 32 and pressed down firmly to complete the cutting of the tissue sample. After the cutting is completed, the frame 20 returns to its initial position under the action of the spring 22. When using the device of this embodiment to sample tissue, the appropriate thickness can be adjusted according to the position of the animal tissue, and the cut surface is smooth and the thickness is controllable.

[0049] Among the optional solutions of this embodiment, it is more preferred that Figure 1 、 Figure 3 and Figure 4 As shown, a first scale line 13 is provided on the operating table 10. The first scale line 13 provides an intuitive measurement standard for the operator. When performing the sampling operation, the position and size of the sample can be accurately determined according to the scale line, thereby accurately controlling the cutting.

[0050] Among the optional solutions of this embodiment, it is more preferred that Figure 1 As shown, the operating table 10 includes a bottom support plate 11 and a base 12; the lower end of the column 20 is fixedly mounted on the bottom support plate 11; the base 12 is detachably fixedly mounted on the upper end surface of the bottom support plate 11, and the nasal tissue sample outline 121 is disposed on the base 12. Dividing the operating table 10 into two layers, the bottom support plate 11 and the base 12, provides more stable support for the entire device: the bottom support plate 11, as the foundation layer, can bear the weight of the column 20 and other components, ensuring that the device does not shake or tilt during use; the base 12 can more specifically carry the nasal tissue sample, keeping the sample stable during the sampling process; different mouse nasal tissue samples have different shapes and sizes, and different bases 12 can be replaced to accommodate different sample collection requirements.

[0051] Specifically, the first scale line 13 is provided on the base 12 .

[0052] Specifically, the detachable connection between the base 12 and the bottom support plate 11 can be any existing connection method, such as a plurality of sockets are provided on the bottom support plate 11, and a plurality of limit columns are fixedly provided at the lower end of the base 12, and the limit columns are inserted and fixed in the corresponding sockets.

[0053] Specifically, the shape of the base 12 can be a rectangular parallelepiped or other shapes, and can be changed into other shapes according to the size of the tissue.

[0054] Specifically, after the tissue sample is fixed according to the nose tissue sample outline 121 on the base 12 , it is placed on the bottom support plate 11 .

[0055] Among them, the relevant structural settings of the frame 20 are described as follows:

[0056] Among the optional solutions of this embodiment, it is more preferred that Figures 1 to 6 As shown, the frame 20 includes two oppositely arranged armrest plates 32 and two oppositely arranged slide rods 31; the two armrest plates 32 and the two slide rods 31 together form a square frame; the slide rod 31 is provided with a sliding groove 311, and the end of the cutting assembly 40 can slide along the first direction in the sliding groove 311; the column 20 has a hollow cavity and a side opening 21 connected to the hollow cavity, and the side opening 21 extends in the vertical direction; the position of each side opening 21 of the square frame is fixedly provided with an extension part 33, and the extension part 33 is located in the hollow cavity; a spring 22 is provided in the hollow cavity below the extension part 33. The square structure is formed by two armrest plates 32 and two slide rods 31, which provides a stable frame 20 foundation for the entire device, thereby driving the cutting assembly 40 to move up and down stably; the sliding groove 311 on the slide rod 31 provides a clear sliding path for the cutting assembly 40, so that the cutting assembly 40 can slide accurately in the first direction; the hollow cavity inside the column 20 and the side opening 21 provide activity space for the square frame and the extension part 33, and the up and down movement of the extension part 33 in the hollow cavity can realize the lifting and lowering adjustment of the entire frame 20; the spring 22 is arranged in the hollow cavity below the extension part 33, which can rebound to the top by itself after the cutting is completed, making room for the sample below to be taken and placed, and facilitating the next cutting operation.

[0057] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figures 3 and 4 As shown, the frame 20 is provided with second scale lines 34 (specifically, the two slide rods 31 are provided with second scale lines 34). The second scale lines 34 are used to indicate the sliding position of the cutting assembly 40 in the first direction. The second scale lines 34 correspond one-to-one with the first scale lines 13. The first scale lines 13 on the operating table 10 and the second scale lines 34 on the frame 20 cooperate with each other to provide a dual reference for the operator. When performing the material collection operation, the operator can observe both scale lines simultaneously to more accurately determine the position of the cutting assembly 40.

[0058] Among them, the relevant setting instructions for the cutting component 40 are as follows:

[0059] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figure 3As shown, there are at least two cutting assemblies 40, each arranged in parallel along a first direction. Multiple cutting assemblies 40 can simultaneously cut the mouse nasal tissue, significantly reducing the sampling time. The parallel arrangement of multiple cutting assemblies 40 ensures consistency in the cutting positions during cutting. The number and spacing of the cutting assemblies 40 can be flexibly adjusted to suit different experimental objectives and sample requirements.

[0060] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figures 3 to 6 As shown, the cutting assembly 40 includes a knife holder 41, a blade 42 and a sliding assembly 43; a shelf groove for placing the blade 42 is provided at the lower end of the knife holder 41; the lower end of the blade 42 has a cutting edge; a sliding assembly 43 is provided at each end of the knife holder 41; the sliding assembly 43 includes a slider 431, a fastening rod 432 and a guide rod 433; the slider 431 slides along a first direction and is arranged in the sliding groove 311; a first sliding guide hole 312 and a second sliding guide hole 313 are provided on two opposite side walls of the sliding groove rod 31, which are connected to the sliding groove 311; the first sliding guide hole 312 is located near the end of the tool holder 41. An internally threaded hole communicating with the resting slot is provided at the end of the tool holder 41. A through-hole is provided on the slider 431. A fastening rod 432 is inserted into the through-hole. One end of the fastening rod 432 passes through the first sliding guide hole 312 and is threadedly connected to the internally threaded hole. The other end of the fastening rod 432 extends out of the second sliding guide hole 313. A guide rod 433 is fixedly provided at the end of the tool holder 41. A third sliding guide hole 314 is provided at a position corresponding to the guide rod 433 on the slide rod 31. The guide rod 433 slides in the third sliding guide hole 314 along a first direction. The cutting assembly 40 adopts a modular design for easy maintenance and replacement. After the blade 42 is placed in the resting slot, it can be fastened by the fastening rods 432 at both ends to ensure the stability of the blade 42. The slider 431 slides in the first direction within the sliding slot 311, while the guide rod 433 slides in the third sliding guide hole 314, providing dual guidance for the movement of the tool holder 41 and ensuring stability in the cutting direction.

[0061] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figures 3 to 6 As shown, the slider 431 is provided with a locking member, which can lock the relative position between the slider 431 and the sliding groove 311. After the slider 431 is adjusted to the appropriate position, the locking member can lock the relative position between the slider 431 and the sliding groove 311, ensuring that the blade 42 does not change position due to accidental sliding during the cutting process, thereby ensuring cutting accuracy; the locking member can ensure the position of each cut and ensure cutting consistency.

[0062] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figures 3 to 6 As shown, the locking member is a locking bolt 44. A fourth sliding guide hole 315 is provided at the upper end of the slide rod 31, communicating with the slide groove 311. A locking threaded hole is provided on the slider 431 at a position corresponding to the fourth sliding guide hole 315. The threaded end of the locking bolt 44 passes through the fourth sliding guide hole 315 and is threadedly connected to the locking threaded hole. As a common and reliable fastening element, the locking bolt 44 provides a strong locking force. Tightening the locking bolt 44 quickly locks the lock, making the locking operation simple and convenient. This locking structure features a compact design, with the locking bolt 44 and associated threaded holes, sliding guide holes, and other components integrated into the slide rod 31 and slider 431, eliminating the need for excessive space.

[0063] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figures 3 to 6 As shown, a knob 434 is fixedly provided at the end of the fastening rod 432 extending out of the second sliding guide hole 313. The design of the knob 434 provides a large, easy-to-grip surface, allowing the operator to easily rotate the knob 434 with a finger or palm; the design of the knob 434 allows the operator to more accurately control the degree of rotation of the fastening rod 432.

[0064] Among them, about other related settings:

[0065] Specifically, the minimum unit of the first scale line 13 and the second scale line 34 is mm. By adjusting the position of the cutting component 40, the minimum thickness of the tissue sample can be achieved to 2 mm; by adjusting the position of the cutting component 40, tiny tissues can be accurately cut and sampled.

[0066] Specifically, an opening is provided at the upper end of the column 20 , and a blocking plug 23 is sealed at the opening.

[0067] The present invention uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only intended to help understand the method and core concept of the present invention. At the same time, those skilled in the art will find that the specific implementation methods and application scopes may vary based on the concept of the present invention. In summary, the contents of this specification should not be construed as limiting the present invention.

Claims

1. A device for collecting rat nasal tissue samples, characterized by: Including operating table and cutting mechanism; The operating table is provided with a nasal tissue sample outline; The cutting mechanism includes a frame and at least one cutting assembly; a column is provided at each of the four corners of the operating table; the frame is located above the operating table and is slidably mounted on each of the columns in a vertical direction; and in a natural state, the frame can maintain a distance from the operating table; The cutting assembly is slidably arranged on the frame along a first direction, wherein the first direction is parallel to the top surface of the operating table and perpendicular to the vertical direction; the lower end of the cutting assembly is provided with a cutting blade.

2. The rat nasal tissue sampling device according to claim 1, characterized in that: The frame includes two oppositely arranged armrest plates and two oppositely arranged slide rods; the two armrest plates and the two slide rods together form a square frame; The slide rod is provided with a slide groove, and the end portion of the cutting assembly can slide along the first direction in the slide groove; The column has a hollow cavity and a side opening communicating with the hollow cavity, and the side opening extends in a vertical direction; An extension portion is fixedly provided at a position of the square frame corresponding to each of the side openings, and the extension portion is located in the hollow cavity; a spring is provided in the hollow cavity below the extension portion.

3. The rat nasal tissue sampling device according to claim 2, characterized in that: The cutting assembly includes a knife holder, a blade and a sliding assembly; The lower end of the blade holder is provided with a shelf groove for placing the blade; the lower end of the blade has the cutting edge; One sliding assembly is respectively provided at each end of the tool holder; the sliding assembly includes a slider, a fastening rod and a guide rod; the slider is slidably arranged in the sliding groove along the first direction; two opposite side walls of the slide rod are provided with a first sliding guide hole and a second sliding guide hole connected to the sliding groove; the first sliding guide hole is close to the end of the tool holder; the end of the tool holder is provided with an internal threaded hole connected to the shelf groove, the slider is provided with a through hole, the fastening rod is passed through the through hole, one end of the fastening rod passes through the first sliding guide hole and is threadedly connected to the internal threaded hole, and the other end of the fastening rod extends out of the second sliding guide hole; The guide rod is fixedly provided at the end of the tool holder, and a third sliding guide hole is provided at a position of the slide rod corresponding to the guide rod. The guide rod is slidably provided in the third sliding guide hole along the first direction.

4. The rat nasal tissue sampling device according to claim 1, characterized in that: A first scale line is provided on the operating table.

5. The rat nasal tissue sampling device according to claim 4, characterized in that: The frame is provided with a second scale line, the second scale line is used to indicate the sliding position of the cutting assembly in the first direction, and the second scale line corresponds to the first scale line one by one.

6. The rat nasal tissue sampling device according to claim 1, characterized in that: The operating table includes a bottom supporting plate and a base; The lower end of the column is fixedly arranged on the bottom supporting plate; The base is detachably fixed on the upper end surface of the bottom support plate, and the nose tissue sample outline is arranged on the base.

7. The device for collecting rat nasal tissue samples according to claim 3, wherein: The slider is provided with a locking member, and the locking member can lock the relative position between the slider and the sliding slot.

8. The device for collecting rat nasal tissue samples according to claim 7, characterized in that: The locking member is a locking bolt; The upper end of the sliding slot rod is provided with a fourth sliding guide hole connected to the sliding slot; A locking threaded hole is provided at a position of the sliding block corresponding to the fourth sliding guide hole, and a threaded end of the locking bolt passes through the fourth sliding guide hole and is threadedly connected in the locking threaded hole.

9. The device for collecting rat nasal tissue samples according to claim 3, wherein: A knob is fixedly provided on the end of the fastening rod extending out of the second sliding guide hole.

10. The device for collecting rat nasal tissue samples according to claim 1, wherein: The number of the cutting components is at least two, and the cutting components are arranged in parallel along the first direction.

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