Immune cell extraction structure
By designing limiting holes and clamping fittings in the immune cell extraction structure, the problem of immune cells being difficult to move as a whole after centrifugation was solved, thereby reducing contamination and improving cell quality.
Patent Information
- Application Number
- CN202422685975.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-05
- Publication Date
- 2025-10-10
- Estimated Expiration
- 2034-11-05
AI Technical Summary
In the prior art, immune cells are difficult to move as a whole after centrifugation and are easily contaminated, resulting in a decrease in cell quality.
An immune cell extraction structure was designed, including a lifting tray and an extraction tube. Through the cooperation of limiting holes, tube clamps and rotating support rods, the overall movement of the extraction tube was achieved, reducing the risk of contamination.
The immune cells can be moved as a whole after centrifugation, which reduces contamination and improves cell quality.
Smart Images

Figure CN223422656U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the related technical field of immune cell extraction auxiliary device, especially to an immune cell extraction structure. BACKGROUND
[0002] Immune cells refer to cells involved in or related to immune response. They include lymphocytes, dendritic cells, monocytes / macrophages, granulocytes, mast cells, etc. Immune cells can be divided into many types, and various immune cells play an important role in the human body. Immune cells (immune cells) are commonly known as white blood cells, including innate lymphocytes, various phagocytes, and lymphocytes that can recognize antigens and produce specific immune responses. General immune cells need to be separated and extracted, and the separation method is mostly using a centrifuge, but multiple test tubes are difficult to move simultaneously, and moving in steps prolongs the process, which can easily contaminate the immune cells or cause the immune cells to differentiate during the process, reducing the quality of the immune cells.
[0003] A stem cell extraction device is disclosed in Chinese Patent No. CN220537783U, authorized on February 27, 2024, in the field of stem cell extraction technology. It includes an extraction table, a stem cell storage test tube, and a stem cell extraction mechanism. The top of the extraction table is provided with a mounting plate, and the mounting plate is provided below with a mounting assembly. The mounting assembly includes a mounting disc, an arc-shaped support plate one, and an arc-shaped support plate two. The bottom of the mounting disc is fixedly connected with a support strip. The inside of the arc-shaped support plate one is provided with a connecting groove. The top and bottom of the connecting groove inner wall are both provided with a recess. One side of the arc-shaped support plate two is fixedly connected with a fixed block. The top and bottom of the fixed block are both fixedly connected with an elastic ball. The fixed block is driven out of the connecting groove by the assistance of two adjusting pieces. The elastic ball is separated from the recess. The arc-shaped support plate two is pushed away to remove and replace the stem cell extraction mechanism. It is convenient to quickly disassemble and replace the stem cell extraction mechanism for the next use after the completion of a round of stem cell extraction. The utility model has the disadvantages that the whole device cannot be moved after centrifugal separation, which can easily contaminate the cells and reduce the quality of the cells. UTILITY MODEL CONTENTS
[0004] The utility model is to overcome the shortcomings of the prior art that the whole device cannot be moved after centrifugal separation, which can easily contaminate the immune cells and reduce the quality of the immune cells. It provides an immune cell extraction structure that can move the whole device after centrifugal separation, reduce the contamination of immune cells, and improve the quality of immune cells.
[0005] To achieve the above-mentioned purpose, the utility model adopts the following technical solutions:
[0006] An immune cell extraction structure includes a lifting tray and an extraction test tube. The lifting tray is provided with a plurality of limiting holes, and the limiting holes are evenly distributed on the lifting tray with the center of the lifting tray as the axis. There are a plurality of extraction test tubes and they correspond one-to-one to the limiting holes. The extraction test tube passes through the limiting hole and is placed in the limiting hole. The limiting hole is provided with a plurality of through holes, and the through holes are evenly distributed on the side wall of the limiting hole with the extraction test tube as the center. A pipe clamping piece is also provided on the lower end surface of the lifting tray. The pipe clamping pieces are in a group of several and evenly surround the limiting hole. The pipe clamping pieces correspond one-to-one to the through holes. The pipe clamping piece is rotatably connected to the lower end surface of the lifting tray, and the extraction test tube is clamped to the lifting tray through the pipe clamping piece.
[0007] During use, the extraction tube has just separated the immune cells in the centrifuge, and then the limiting hole on the lifting tray is aligned with the extraction tube, and it is pressed downward in the direction of the extraction tube to allow the upper end of the extraction tube to pass through the limiting hole. The inner end of the tube clamp will turn upward in the through hole, and then the tube clamp is allowed to reach the bottom of the raised part of the extraction tube. The lifting tray is lifted upward, and all the extraction tubes can be lifted and transferred at once, doubling the speed. After use, the extraction tube can be taken out by moving the extraction tube upward, thereby achieving the purpose of being able to move the entire tube after centrifugal separation, reducing problems such as contamination of immune cells, and thus improving the quality of immune cells.
[0008] Preferably, a support block is provided on the lower end surface of the lifting tray, wherein the support blocks are provided in a plurality and correspond one to one with the through holes. The upper end surface of the support block is fixedly connected to the lower end surface of the lifting tray. The tube clamping member includes a rotating shaft and a rotating support rod. The inner end of the rotating support rod contacts the extraction test tube, and the outer end of the rotating support rod contacts the lower end surface of the lifting tray. The rotating support rod is rotatably connected to the support block via the rotating shaft, and the extraction test tube is clamped to the lifting tray via the rotating support rod. Half of the rotating support rod is within the limiting hole, and the other half is below the lifting tray, which facilitates the passage of the extraction test tube and can also clamp the extraction test tube.
[0009] Preferably, the extraction tube is provided with a support ring, which surrounds and is fixedly connected to the outer side of the extraction tube. The inner end of the rotating support rod contacts the lower end of the support ring, and the extraction tube is engaged with the lifting plate through the cooperation of the support ring and the rotating support rod. The support ring facilitates engagement with the rotating support rod to lift the extraction tube.
[0010] Preferably, the extraction test tube is provided with a test tube cover, the lower end surface of the test tube cover is provided with a sealing block, the cross-sectional shape of the sealing block forms a trapezoid, the trapezoidal long side of the sealing block is fixedly connected to the lower end surface of the test tube cover, the lower end of the sealing block is placed in the extraction test tube, the lower end surface of the test tube cover is placed on the upper end surface of the extraction test tube, the lifting tray is provided with a supporting rod, the supporting rods are provided and evenly surround the limiting hole, the lower end surface of the supporting rods is fixedly connected to the upper end surface of the lifting tray, and the test tube cover is clamped to the lifting tray via the supporting rods. The test tube cover is convenient for reducing dust from entering the test tube, and the cross-sectional shape of the sealing block forms a trapezoid, which facilitates the sealing block to quickly seal the test tube.
[0011] Preferably, the test tube cap is provided with a support block on the side thereof. There are multiple support blocks, each corresponding to a support rod. A slot is provided on the lower end surface of each support block, through which the support block engages with the support rod. The support block, slot, and support rod facilitate placing the test tube cap in place before removing the test tube, allowing the cap to be replaced simultaneously with the test tube, thus reducing tube removal time.
[0012] Preferably, a handle is provided at the center of the upper end surface of the lifting tray, and the lower end surface of the handle is fixedly connected to the upper end surface of the lifting tray. The handle makes it easy to take the lifting tray.
[0013] The beneficial effects of the utility model are: it can move as a whole after centrifugal separation, reducing problems such as contamination of immune cells and thus improving the quality of immune cells; half of the rotating support rod is in the limiting hole, and the other half is under the lifting tray, which is convenient for passing the extraction test tube and clamping the extraction test tube; the supporting ring is conveniently engaged with the rotating support rod to lift the extraction test tube; the test tube cover is convenient for reducing dust from entering the test tube, and the cross-sectional shape of the sealing block is trapezoidal, which is convenient for the sealing block to quickly seal the test tube; the supporting block, the card slot and the supporting rod are convenient for putting the test tube cover in position in advance when taking out the extraction test tube, and the cover can be covered at the same time when taking out the test tube, reducing the time for taking out the tube; the handle is convenient for taking the lifting tray. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is a structural diagram of the utility model;
[0015] Figure 2 yes Figure 1 An enlarged view of detail A;
[0016] Figure 3 It is a cross-sectional view of the main view of the present utility model;
[0017] Figure 4 yes Figure 2 Cross-sectional view of BB;
[0018] Figure 5 yes Figure 3 An enlarged view of detail C;
[0019] Figure 6 yes Figure 4 Magnified view of detail D.
[0020] In the figure: 1. Lifting tray, 2. Extraction test tube, 3. Limiting hole, 4. Through hole, 5. Support block, 6. Rotating shaft, 7. Rotating support rod, 8. Support ring, 9. Test tube cover, 10. Sealing block, 11. Support block, 12. Support rod, 13. Slot, 14. Handle. DETAILED DESCRIPTION
[0021] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.
[0022] like Figure 1 and Figure 3 In the embodiment, an immune cell extraction structure is provided, which includes a lifting tray 1 and an extraction test tube 2. The lifting tray 1 is provided with a plurality of limiting holes 3, and the limiting holes 3 are evenly distributed on the lifting tray 1 with the center of the lifting tray 1 as the axis. There are several extraction test tubes 2 and they correspond one-to-one with the limiting holes 3. The extraction test tube 2 passes through the limiting hole 3 and is placed in the limiting hole 3. The limiting hole 3 is provided with a plurality of through holes 4, and the through holes 4 are evenly distributed on the side wall of the limiting hole 3 with the extraction test tube 2 as the center. A tube clamping piece is also provided on the lower end surface of the lifting tray 1. The tube clamping piece is in a group of several and evenly surrounds the limiting hole 3. The tube clamping piece corresponds one-to-one to the through holes 4. The tube clamping piece is rotatably connected to the lower end surface of the lifting tray 1, and the extraction test tube 2 is clamped to the lifting tray 1 through the tube clamping piece.
[0023] like Figure 1 、 Figure 3 and Figure 5 As shown, a support block 5 is provided on the lower end surface of the lifting tray 1. There are several support blocks 5 and they correspond one to one with the through holes 4. The upper end surface of the support block 5 is fixedly connected to the lower end surface of the lifting tray 1. The tube clamping member includes a rotating shaft 6 and a rotating support rod 7. The inner end of the rotating support rod 7 is in contact with the extraction test tube 2, and the outer end of the rotating support rod 7 is in contact with the lower end surface of the lifting tray 1. The rotating support rod 7 is rotatably connected to the support block 5 through the rotating shaft 6, and the extraction test tube 2 is clamped to the lifting tray 1 through the rotating support rod 7.
[0024] like Figure 3 and Figure 5 As shown, a support ring 8 is provided on the extraction tube 2, which surrounds the outer surface of the extraction tube 2 and is fixedly connected to the outer surface of the extraction tube 2. The inner end of the rotating support rod 7 contacts the lower end surface of the support ring 8, and the extraction tube 2 is clamped with the lifting tray 1 through the cooperation of the support ring 8 and the rotating support rod 7.
[0025] like Figure 1 and Figure 2As shown, the extraction test tube 2 is provided with a test tube cover 9, and a sealing block 10 is provided on the lower end surface of the test tube cover 9. The cross-sectional shape of the sealing block 10 forms a trapezoid, and the long side of the trapezoid of the sealing block 10 is fixedly connected to the lower end surface of the test tube cover 9. The lower end of the sealing block 10 is placed in the extraction test tube 2, and the lower end surface of the test tube cover 9 is placed on the upper end surface of the extraction test tube 2. A supporting rod 12 is provided on the lifting tray 1, and there are several supporting rods 12 that are evenly arranged around the limiting hole 3. The lower end surface of the supporting rod 12 is fixedly connected to the upper end surface of the lifting tray 1, and the test tube cover 9 is clamped with the lifting tray 1 through the supporting rod 12.
[0026] like Figure 4 and Figure 6 As shown, a support block 11 is provided on the side of the test tube cover 9. There are several support blocks 11 and they correspond one to one with the support rods 12. A slot 13 is provided on the lower end surface of the support block 11. The support block 11 is connected to the support rod 12 through the slot 13.
[0027] like Figure 1 and Figure 3 As shown, a handle 14 is provided at the center of the upper end surface of the lifting tray 1 , and the lower end surface of the handle 14 is fixedly connected to the upper end surface of the lifting tray 1 .
[0028] When in use, first align the card slot 13 on the support block 11 of the test tube cover 9 with the support rod 12, and place the test tube cover 9 on the drag rod 12. Then, extract the test tube 2 just after separating the immune cells in the centrifuge, and then use the handle 14 to lift the lifting tray 1, align the limiting hole 3 on the lifting tray 1 with the extraction test tube 2, press downward in the direction of the extraction test tube 2, let the upper end of the extraction test tube 2 pass through the limiting hole 3, and the inner end of the rotating support rod 7 will turn upward in the through hole 4 along the support block 5 and the rotating shaft 6 as the center, and the extraction test tube 2 reaches the position of the test tube cover 9, and then the sealing block 10 is raised. It will enter the extraction test tube 2 to achieve a sealing effect, and then the rotating support rod 7 is allowed to reach the bottom of the supporting ring 8, and the lifting plate 1 is lifted upward. The rotating support rod 7 will use the inner end of the rotating support rod 7 to clamp the supporting ring 8 because the outer end is blocked by the lifting plate 1. In this way, all the extraction test tubes 2 can be lifted and transferred at one time, and the speed is doubled. After the extraction test tube 2 is used, if it needs to be taken out, the extraction test tube 2 can be moved upward to separate it, thereby achieving the purpose of being able to move as a whole after centrifugal separation, reducing problems such as contamination of immune cells, and thus improving the quality of immune cells.
Claims
1. An immune cell extraction structure, characterized in that: The invention comprises a lifting tray (1) and an extraction test tube (2), wherein the lifting tray (1) is provided with a plurality of limiting holes (3), the limiting holes (3) are evenly distributed on the lifting tray (1) with the center of the lifting tray (1) as the axis, the extraction test tube (2) is provided with a plurality of limiting holes (3) and corresponds one to one with the limiting holes (3), the extraction test tube (2) passes through the limiting hole (3) and is placed in the limiting hole (3), the limiting hole (3) is provided with a plurality of through holes (4), the through holes (4) are evenly distributed on the side wall of the limiting hole (3) with the extraction test tube (2) as the center, the lower end surface of the lifting tray (1) is further provided with a pipe clamping member, the pipe clamping member is a group of a plurality of pipe clamping members and is evenly surrounded around the limiting hole (3), the pipe clamping member corresponds one to one with the through holes (4), the pipe clamping member is rotatably connected to the lower end surface of the lifting tray (1), and the extraction test tube (2) is clamped to the lifting tray (1) through the pipe clamping member.
2. The immune cell extraction structure according to claim 1, characterized in that: A support block (5) is provided on the lower end surface of the lifting tray (1). There are a plurality of support blocks (5) corresponding to the through holes (4) one by one. The upper end surface of the support block (5) is fixedly connected to the lower end surface of the lifting tray (1). The tube clamping member includes a rotating shaft (6) and a rotating support rod (7). The inner end of the rotating support rod (7) contacts the extraction test tube (2), and the outer end of the rotating support rod (7) contacts the lower end surface of the lifting tray (1). The rotating support rod (7) is rotatably connected to the support block (5) through the rotating shaft (6), and the extraction test tube (2) is clamped to the lifting tray (1) through the rotating support rod (7).
3. The immune cell extraction structure according to claim 2, characterized in that: The extraction test tube (2) is provided with a supporting ring (8), which surrounds the outer side of the extraction test tube (2) and is fixedly connected to the outer side of the extraction test tube (2). The inner end of the rotating support rod (7) contacts the lower end surface of the supporting ring (8). The extraction test tube (2) is clamped to the lifting tray (1) through the cooperation of the supporting ring (8) and the rotating support rod (7).
4. The immune cell extraction structure according to claim 1, characterized in that: The extraction test tube (2) is provided with a test tube cover (9), and a sealing block (10) is provided on the lower end surface of the test tube cover (9). The cross-sectional shape of the sealing block (10) forms a trapezoid, and the long side of the trapezoid of the sealing block (10) is fixedly connected to the lower end surface of the test tube cover (9). The lower end of the sealing block (10) is placed in the extraction test tube (2), and the lower end surface of the test tube cover (9) is placed on the upper end surface of the extraction test tube (2). The lifting tray (1) is provided with a supporting rod (12), and the supporting rod (12) is provided in a plurality of ways and is evenly surrounded around the limiting hole (3). The lower end surface of the supporting rod (12) is fixedly connected to the upper end surface of the lifting tray (1), and the test tube cover (9) is clamped with the lifting tray (1) through the supporting rod (12).
5. The immune cell extraction structure according to claim 4, characterized in that: A support block (11) is provided on the side of the test tube cover (9). There are a plurality of support blocks (11) corresponding to the support rods (12) one by one. A clamping groove (13) is provided on the lower end surface of the support block (11). The support block (11) is clamped with the support rod (12) through the clamping groove (13).
6. The immune cell extraction structure according to claim 1, characterized in that: A handle (14) is provided at the center of the upper end surface of the lifting tray (1), and the lower end surface of the handle (14) is fixedly connected to the upper end surface of the lifting tray (1).
Citation Information
Patent Citations
Stem cell extraction device
CN220537783U