Membrane passing device for detecting alkaloid in cosmetics

Abstract

The utility model belongs to the technical field of chromatographic analysis and detection devices, and particularly relates to a membrane passing device for detecting alkaloid in cosmetics, which comprises a filter tube, a vacuum glass box, drainage tubes and a sample introduction bottle, a plurality of drainage tube connectors are uniformly distributed at the top of the vacuum glass box, and the filter tube comprises a liquid adding tube and a filter assembly. The liquid adding pipe, the filtering assembly and the drainage pipe are sequentially communicated in a sealed mode from top to bottom, the vacuum glass box is provided with a vacuum meter, a ventilation pipe opening and a vacuumizing pipe opening, the ventilation pipe opening and the vacuumizing pipe opening are each provided with a control valve, and the bottom of the vacuum glass box is provided with a drawing supporting plate capable of containing a sample injection bottle. The vacuum glass box is provided with an opening through which the drawing support plate and the sample introduction bottle can pass, and one end of the drawing support plate is fixedly connected with a sealing plate capable of sealing the opening. The liquid adding and sampling are convenient, the hand holding is not needed in the filtering process, the vacuum pressure can be adjusted, the filtering speed can be controlled, and the device is particularly suitable for treating a large batch of samples.

Description

Technical Field

[0001] The utility model belongs to the technical field of chromatographic analysis detection devices, and particularly relates to a membrane device for detecting alkaloids in cosmetics. Background Art

[0002] Alkaloids often remain in cosmetics, and their content is generally determined by chromatography. Due to the precision of the chromatography system and the accuracy requirements of the analysis results, the sample extract must be filtered through a filter membrane before entering the chromatograph for analysis. Filtration can protect the chromatography system and chromatographic column, extend the column life, and improve data accuracy. In addition, filtration can eliminate pressure fluctuations caused by friction particles and baseline fluctuations caused by irregular impurities, and eliminate interference with the detection system due to the presence of bubbles. In the prior art, laboratory operators usually use a handheld pipette to extract the sample extract from the sample tube, then insert the pipette into the filter membrane assembly and pump the sample extract from the pipette. The sample extract is filtered through the filter membrane and enters the collection tube, thus completing the filtration and transfer process of the sample liquid in the sample tube. The filtration process is largely manual and cumbersome. In addition, the filtration process generally uses a positive pressure push method, which is difficult to control the pressure. The filtration process is unstable and easily clogs the filter membrane. Especially when processing large quantities of samples, it is time-consuming and labor-intensive, seriously affecting experimental efficiency. Utility Model Content

[0003] In response to the above problems, the purpose of the present invention is to provide a membrane filter device that is convenient for liquid loading, has a stable filtration process, can adjust the vacuum pressure according to the resistance during the filtration process, thereby controlling the filtration speed and preventing blockage. It is particularly suitable for processing large quantities of samples, saves time and effort, and can effectively improve experimental efficiency.

[0004] The utility model discloses a membrane device for alkaloid detection in cosmetics, including filter tube, vacuum glass box, drainage tube, sample bottle, vacuum glass box top all has a plurality of drainage tube interfaces, the filter tube includes liquid adding pipe and filter assembly, be equipped with liquid adding pipe mouth on the liquid adding pipe, the liquid adding pipe, filter assembly and drainage tube are linked by sealed connection structure from top to bottom and are communicated in proper order, the lower end of drainage tube inserts vacuum glass box from drainage tube interface and is sealedly connected between drainage tube and drainage tube interface, a plurality of the drainage tube interface is equipped with detachable plugging structure on the interface of other not connecting drainage tube, be equipped with vacuum gauge, air pipe mouth and with the vacuum pipe mouth of communicating of vacuum extraction pipeline on vacuum glass box, all be provided with control valve on air pipe mouth and vacuum pipe mouth, and vacuum glass box bottom is equipped with the pull -out tray of can place sample bottle, the pull -out tray is slidably arranged below the position of drainage tube through the sliding groove connection structure, vacuum glass box is equipped with the opening of the side of pull -out tray pull -out direction opposite, and the pull -out tray and sample bottle can pass through, one end of pull -out tray and opening is fixedly connected with the sealing plate of the opening of can block, be equipped with pull -out handle on the sealing plate, and be equipped with elastic sealing washer between opening and sealing plate.

[0005] Further, the opening is integrally connected with an adapter interface matched with the edge of the sealing plate, and the inner side of the adapter interface and the edge of the sealing plate are both provided with an elastic pad layer.

[0006] Further, the pull-out tray is slidably connected on the two side walls of the vacuum glass box through the sliding groove connection structure.

[0007] Further, the filter assembly comprises a straight pipe section, a reducing pipe section and a drainage pipe section integrally connected from top to bottom, the upper end of the straight pipe section is threadedly connected with the liquid adding pipe, and the lower end of the drainage pipe section is sealingly connected with the drainage pipe, the straight pipe section is provided with a membrane passing mechanism, and the drainage pipe section is provided with a flow control valve.

[0008] Further, the lower end of the drainage pipe section is integrally connected with the drainage pipe.

[0009] Further, the membrane passing mechanism comprises a mounting ring horizontally mounted on the inner wall of the straight pipe section, the mounting ring is provided with an annular groove for fixing the filter membrane, guide grooves are vertically arranged on the left and right sides of the inner wall of the straight pipe section, a compression ring for preventing deformation or displacement of the filter membrane is arranged on the mounting ring, the bottom of the compression ring is provided with a convex ring matched with the annular groove, guide rods are symmetrically arranged on the left and right sides of the compression ring, the guide rods are slidingly connected in the guide grooves, the upper end of the guide rod is provided with a hand-held portion for pushing and pulling the guide rod up and down, and the filter membrane is mounted between the mounting ring and the compression ring, which can effectively prevent deformation of the filter membrane and facilitate replacement and installation.

[0010] Further, when the compression ring is pressed on the filter membrane, the upper end of the guide rod extends out of the guide groove, and the inner wall of the liquid adding pipe is provided with a limiting plate for preventing the guide rod from sliding upward.

[0011] Further, the inner circle of the mounting ring is integrally connected with a mesh plate, and when the filtering resistance is large, the filtering pressure difference can be increased by vacuumizing, and the mesh plate structure can prevent the filter membrane from being deformed due to excessive pressure.

[0012] Further, the detachable sealing structure is a sealing rod, which is simple in structure and convenient to seal and extract.

[0013] Further, the vacuum glass box is placed on the support platform, and a lifting platform is arranged outside the opening of the vacuum glass box, and guide rollers are arranged on the lifting platform along the pulling direction of the pulling tray, so that the pulling tray can be pulled out of the vacuum glass box to take the sample bottle.

[0014] Further, a groove for fixing the sample bottle is arranged on the pulling tray opposite to each of the drainage tubes, and an elastic rubber pad is arranged in the groove.

[0015] Further, the liquid inlet port of the liquid adding pipe is funnel-shaped, so that the sample extraction liquid in the sample tube can be directly poured into the liquid adding pipe through the liquid adding pipe, which is convenient and fast.

[0016] Further, the lower end of the drainage tube is connected with a drainage nozzle through a transition hose.

[0017] In the utility model, the sample extraction liquid can be directly placed into the liquid adding pipe through the liquid adding pipe, and the vacuum glass box is vacuumized through the vacuum pipeline connected with the vacuum pipeline port, and the vacuum degree in the box is observed through the vacuum gauge, and when the vacuum pressure required for filtering is reached, the vacuumization is stopped and the control valve on the vacuum pipeline port is closed, and when the filtering pressure difference is too large or the filtering is completed, the release of the vacuum pressure can be adjusted through the control valve on the air inlet port, and after the sample extraction liquid is filtered through the filtering assembly and is drained through the drainage tube, the sample extraction liquid falls into the sample bottle placed on the pulling tray below the drainage tube, and when filtering, the opening is sealed by the sealing plate, and the elastic sealing ring between the opening and the sealing plate can prevent air leakage, and after the filtering is completed, the pulling tray and the sample bottle placed thereon are pulled out of the box through the pulling handle on the sealing plate, so that the required sample bottle can be taken at any time according to the progress of the chromatographic analysis, and the chromatographic analysis efficiency is effectively improved.

[0018] Beneficial effects: the utility model is convenient for adding liquid, stable in filtering process, and does not need to be held during the filtering process, the vacuum pressure can be adjusted according to the resistance in the filtering process, so as to control the filtering speed and prevent blockage, especially suitable for processing a large number of samples, time-saving and labor-saving, and the sample bottle is convenient to take, and the experimental efficiency can be effectively improved. BRIEF DESCRIPTION OF DRAWINGS

[0019] Hereinafter, the utility model will be described in more detail by way of example with reference to the accompanying drawings, in which:

[0020] Figure 1 : Structure schematic diagram of embodiment 1 of the utility model.

[0021] Figure 2 : Structure schematic diagram of the structure that draws out the sample bottle from the opening together with the pull-out tray of embodiment 1 of the utility model.

[0022] Figure 3 : Installation structure schematic diagram of filter assembly in embodiment 2 of the utility model.

[0023] Figure 4 : Installation structure schematic diagram of membrane passing mechanism in embodiment 3 of the utility model.

[0024] Figure 5 : Position installation schematic diagram of guide rod on compression ring in embodiment 3 of the utility model.

[0025] In the figure: 01. sample bottle, 02. support platform, 03. lifting platform, 04. lead-in support roller, 1. filter pipe, 2. vacuum glass box, 3. drainage pipe, 11. liquid adding pipe, 111. liquid adding pipe mouth, 12. filter assembly, 21. vacuum gauge, 22. breather pipe mouth, 23. vacuum extraction pipeline, 24. vacuum extraction pipe mouth, 25. control valve, 26. pull-out tray, 27. sliding groove connecting structure, 28. opening, 29. sealing plate, 31. drainage pipe interface, 32. detachable plugging structure, 33. transition hose, 34. liquid discharge pipe nozzle, 121. straight pipe section, 122. reducing pipe section, 123. drainage pipe section, 124. membrane passing mechanism, 125. flow control valve, 261. groove, 281. adaptive interface, 291. pull-out handle, 292. elastic sealing washer, 1241. mounting ring, 1242. filter membrane, 1243. annular groove, 1244. guide groove, 1245. compression ring, 1246. convex ring, 1247. guide rod, 1248. limiting plate. DETAILED DESCRIPTION

[0026] In the utility model, in order to facilitate the description, the relative position relation of each component is described according to the layout mode of the drawings of the specification, such as: the position relation of up, down, left, right and the like is determined according to the layout direction in the drawings of the specification.

[0027] Embodiment 1, refer to Figure 1 , Figure 2The utility model provides a kind of membrane device for detecting alkaloid in cosmetics, including filter tube 1, vacuum glass box 2, drainage tube 3, sample bottle 01, the vacuum glass box 2 top is evenly distributed with multiple drainage tube interfaces 31, the filter tube 1 includes liquid feeding pipe 11 and filter assembly 12, the liquid feeding pipe 11 is equipped with liquid feeding pipe mouth 111, the liquid feeding pipe 11, filter assembly 12 and drainage tube 3 are sequentially connected by sealed connection structure from top to bottom, the drainage tube 3 lower end is inserted into vacuum glass box 2 from the drainage tube interface 31, and the drainage tube 3 and drainage tube interface 31 are sealed connection, the drainage tube interface 31 of multiple other not connected drainage tube 3 is equipped with detachable plugging structure 32, the vacuum glass box 2 is equipped with vacuum gauge 21, air pipe mouth 22 and vacuum extraction pipe mouth 24 being communicated with vacuum extraction pipeline 23, the air pipe mouth 22 and vacuum extraction pipe mouth 24 are all provided with control valve 25, and the vacuum glass box 2 bottom is equipped with the pull-out tray plate 26 that can place sample bottle 01, the pull-out tray plate 26 is slidably arranged in the position below drainage tube 3 by sliding groove connection structure 27, the side of vacuum glass box 2 opposite pull-out tray plate 26 pull-out direction is equipped with the opening 28 that can contain pull-out tray plate 26 and sample bottle 01 pass, the one end of pull-out tray plate 26 and opening 28 is fixedly connected with the sealing plate 29 that can block opening 28, the sealing plate 29 is equipped with pull-out handle 291, and the opening 28 and sealing plate 29 are equipped with elastic sealing washer 292.

[0028] The opening 28 is integrally connected with the matching interface 281 matched with the edge of the sealing plate 29, and the inner side of the matching interface 281 and the edge of the sealing plate 29 are both provided with an elastic pad layer.

[0029] The detachable plugging structure 32 is a sealing rod, which is simple in structure and convenient to seal and extract.

[0030] The vacuum glass box 2 is placed on the support platform 02, and the opening outside of the vacuum glass box 2 is provided with a lifting platform 03.

[0031] The pull-out tray plate 26 is provided with a groove 261 for fixing the sample bottle 01 opposite each drainage tube 3, and the inner side of the groove 261 is mounted with an elastic rubber pad.

[0032] The liquid inlet port of the liquid feeding pipe mouth 111 is funnel-shaped, which is convenient for pouring the sample extraction liquid in the sample tube directly into the liquid feeding pipe 11 from the liquid feeding pipe mouth 111.

[0033] The utility model discloses a direct self liquid filling pipe mouth 111 can be placed into liquid filling pipe 11 with sample extraction liquid, simultaneously utilize the vacuum extraction pipeline 23 who links with vacuum extraction pipe mouth 24 intercommunication to the vacuum glass box 2 in carries out vacuum extraction, through the vacuum table 21 observation the vacuum degree in the box body, when reaches the vacuum pressure required by filtration, stop vacuum extraction and close the control valve 25 on vacuum extraction pipe mouth 24, when the filtration pressure difference is too big or filtration ends, can pass through the control valve 25 on the air vent pipe mouth 22 to adjust the release vacuum pressure, after sample extraction liquid filters through the filter assembly 12 and is drained through the drainage tube 3, falls into the sample bottle 01 that the drainage tube 3 below places on the pullout tray 26, when filtering, utilize the sealing plate 29 to carry out the plugging of the opening 28, the elastic sealing washer 292 between the opening 28 and sealing plate 29 can prevent the air leakage, after filtration ends, directly through the pullout handle 291 on the sealing plate 29 pulls out the pullout tray 26 together with the sample bottle 01 that it places on from the opening 28 vacuum glass box 2, according to the chromatographic analysis progress, the required sample bottle 01 is taken at any time, effectively improves the chromatographic analysis efficiency.

[0034] Example 2, refer to Figure 3 , as the further optimization design of implementation 1, the filter assembly 12 includes the straight pipe section 121, the reducing pipe section 122 and the drainage pipe section 123 that are integrally connected from top to bottom, the upper end of the straight pipe section 121 is threadedly connected with the liquid filling pipe 11, and the lower end of the drainage pipe section 123 is threadedly connected with the drainage tube 3, the straight pipe section 121 is provided with a membrane passing mechanism 124, the drainage pipe section 123 is provided with a flow control valve 125, and the lower end of the drainage tube 3 is connected with a liquid discharge nozzle 34 through a transition hose 33.

[0035] Example 3, refer to Figure 4 、 Figure 5 , as the further optimization design of example 2, the membrane passing mechanism 124 includes a mounting ring 1241 horizontally mounted on the inner wall of the straight pipe section 121, the mounting ring 1241 is provided with an annular groove 1243 for fixing a filter membrane 1242, the inner wall of the straight pipe section 11 is vertically provided with a guide groove 1244 on the left and right sides of the mounting ring 1241, the mounting ring 1241 is provided with a compression ring 1245 for preventing the filter membrane 1242 from deforming or displacing, the compression ring 1245 is provided with a convex ring 1246 at the bottom for matching the annular groove 1243, the compression ring 1245 is symmetrically provided with a guide rod 1247 on the left and right sides, the guide rod 1247 is slidably connected in the guide groove 1244, and the guide rod 1247 is provided with a hand-held portion at the upper end for pushing and pulling the guide rod 1247 up and down, and the filter membrane 1242 is mounted between the mounting ring 1241 and the compression ring 1245, which can effectively prevent the filter membrane 1242 from deforming and is convenient to replace and install.

[0036] When the pressing ring 1245 presses on the filter membrane 1242, the upper end of the guide rod 1247 extends out of the guide groove 1244, and the inner wall of the liquid adding pipe 11 is provided with a limiting plate 1248 for preventing the guide rod 1247 from sliding upward.

[0037] The inner circle of the mounting ring 1241 is integrally connected with a mesh plate, and when the filtering resistance is large, vacuum can be drawn to increase the filtering pressure difference, and the mesh plate structure can prevent the filter membrane 1242 from being deformed due to excessive pressure.

[0038] The basic principle, main features and advantages of the present application are shown and described above. It should be understood by those skilled in the art that the present application is not limited by the above embodiments, and the above embodiments and descriptions in the specification are only preferred examples of the present application and do not limit the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the present application. The scope of protection of the present application is defined by the appended claims and their equivalents.

Claims

1. A membrane device for detecting alkaloids in cosmetics, characterized in that: It includes a filter tube, a vacuum glass box, a drainage tube, and a sample injection bottle. The top of the vacuum glass box is evenly distributed with multiple drainage tube interfaces. The filter tube includes a liquid adding tube and a filter assembly. The liquid adding tube is provided with a liquid adding tube port. The liquid adding tube, the filter assembly and the drainage tube are sequentially connected from top to bottom through a sealed connection structure. The lower end of the drainage tube is inserted into the vacuum glass box from the drainage tube interface and the drainage tube and the drainage tube interface are sealed. The other interfaces of the multiple drainage tube interfaces that are not connected to the drainage tube are provided with a detachable blocking structure. The vacuum glass box is provided with a vacuum gauge, The vent pipe opening and the vacuum pipe opening connected to the vacuum pipe, the vent pipe opening and the vacuum pipe opening are both provided with control valves, and the bottom of the vacuum glass box is provided with a pull-out tray for placing sampling bottles, the pull-out tray can be slidably set below the drainage tube through a slide connection structure, and the vacuum glass box is provided with an opening for accommodating the pull-out tray and the sampling bottle to pass through on the side facing the pulling direction of the pull-out tray, the end of the pull-out tray connected to the opening is fixedly connected to a sealing plate that can seal the opening, the sealing plate is provided with a pulling handle, and an elastic sealing gasket is provided between the opening and the sealing plate.

2. A membrane device for detecting alkaloids in cosmetics according to claim 1, characterized in that: An adapting interface that matches the edge of the sealing plate is integrally connected to the opening, and an elastic cushion layer is provided on the inner side of the adapting interface and the edge of the sealing plate.

3. A membrane device for detecting alkaloids in cosmetics according to claim 1, characterized in that: The pull-out supporting plate can be slidably connected to the two side walls of the vacuum glass box through a sliding groove connection structure.

4. A membrane device for detecting alkaloids in cosmetics according to any one of claims 1 to 3, characterized in that: The filter assembly includes a straight pipe section, a reducing pipe section and a drainage pipe section that are integrally connected from top to bottom. The upper end of the straight pipe section is threadedly connected to the liquid adding pipe and the lower end of the drainage pipe section is sealed to the drainage pipe. The straight pipe section is equipped with a membrane passing mechanism, and a diversion control valve is provided on the drainage pipe section.

5. A membrane device for detecting alkaloids in cosmetics according to claim 4, characterized in that: The membrane passing mechanism includes a mounting ring horizontally mounted on the inner wall of the straight pipe section, the mounting ring is provided with an annular groove for fixing the filter membrane, the inner wall of the straight pipe section is vertically provided with guide grooves on the left and right sides of the mounting ring, a pressure ring is mounted on the mounting ring to prevent the filter membrane from deformation or displacement, a convex ring is provided at the bottom of the pressure ring to cooperate with the annular groove, guide rods are symmetrically provided on the left and right sides of the pressure ring, the guide rods are slidably connected in the guide groove, and the upper end of the guide rod is provided with a hand-held portion for pushing and pulling the guide rod up and down, and the filter membrane is mounted between the mounting ring and the pressure ring.

6. A membrane device for detecting alkaloids in cosmetics according to claim 5, characterized in that: When the pressure ring is pressed on the filter membrane, the upper end of the guide rod extends upward from the guide groove, and the inner wall of the liquid adding tube is provided with a limit plate to prevent the guide rod from sliding upward.

7. A membrane device for detecting alkaloids in cosmetics according to claim 5, characterized in that: A mesh plate is integrally connected to the inner circle of the mounting ring.

8. A membrane device for detecting alkaloids in cosmetics according to claim 1, characterized in that: The detachable sealing structure is a sealing rod.

9. A membrane device for detecting alkaloids in cosmetics according to claim 1, characterized in that: The vacuum glass box is placed on a supporting platform, and a lifting platform is provided outside the opening of the vacuum glass box. The lifting platform is provided with guiding rollers along the pulling direction of the pulling support plate.

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