Test paper disc for drug sensitivity test

Abstract

The utility model provides a test paper disc for drug sensitivity detection, which belongs to the field of medical treatment and comprises a shell, a fixed clamping component and a test paper disc, wherein the fixed clamping assembly comprises a fixed block, a movable plate, a movable shaft, a tooth groove, a first limiting block, a second limiting block, a spring, a fixed disc, a rotating shaft, a fixed inclined cutting block, a first limiting groove, a second limiting groove and a third limiting groove, the fixed block is fixedly arranged at the bottom of the inner wall of the shell, and the movable plate is slidably connected to the upper portion of the outer wall of the fixed block; the moving shaft is fixedly arranged at the center of the bottom of the moving plate, and the first limiting block is fixedly arranged at the bottom of the moving plate. By starting the fixing and clamping assembly, the two fixing inclined cutting blocks can fix the test paper in the front-back direction, the situation that the stability of the test paper is affected by external factors is avoided, the accuracy of a drug sensitive test result is guaranteed, and the test paper is more convenient to fix and release under the interaction of the fixing inclined cutting blocks and the fixing blocks through the elasticity of springs.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the medical field, concretely relates to a drug sensitive detection test paper disc. BACKGROUND

[0002] Drug sensitive detection test paper disc is a complex and delicate process, paper piece diffusion method (Disk Diffusion Method): this is a traditional drug sensitive test method, and the filter paper piece containing the quantitative antibacterial drug is pasted on the agar surface that has been inoculated with the test bacteria. The drug in the paper piece diffuses in the agar, forms the concentration gradient, thereby forms the transparent bacteriostatic ring around the paper piece. The size of the bacteriostatic ring can reflect the sensitivity of the test bacteria to the drug, and is negatively correlated with the minimum inhibitory concentration (MIC) of the drug to the test bacteria. Dilution method: the dilution method drug sensitive test can be used for quantitative test of the in vitro activity of the antibacterial drug to a certain bacteria, and is divided into agar dilution method and broth dilution method. When the experiment, the concentration of the antibacterial drug is usually dilution by ratio, and the minimum drug concentration that can inhibit the visible growth of the bacteria to be tested becomes the minimum inhibitory concentration (MIC). MIC drug sensitive test paper intersection method: this method is used for measuring the MIC value of a single antibacterial drug, and two MIC drug sensitive test papers are combined into 90 degree intersection and placed on the MH agar plate containing the bacteria to be tested, so as to measure the MIC value of the antibacterial drug combination. By calculating the fractional inhibitory concentration index (FIC index), the combined effect (synergistic, additive or antagonistic) of two drugs can be judged. Antibiotic combined drug sensitive detection disc: this is a patented technology, which combines the detection reliability of MIC drug sensitive strip and is used for promoting and standardizing the detection and analysis of antibiotic in vitro combined drug sensitivity. This detection disc uses a patented tool, which aims to help operators improve the simplicity and repeatability of operation in the combined drug sensitive test. Principle of drug sensitive test: the principle of drug sensitive test is to evaluate the sensitivity or drug resistance of bacteria to antibiotics by determining the interaction between antibiotics and bacteria. The commonly used drug sensitive test methods include paper piece method, McFarland method and E test method.

[0003] The shortcomings of the drug sensitivity test paper disc that cannot stably fix the test paper mainly include the following aspects: material influence: the material of the test paper sheet has a great influence on the stability and activity of the drug. If ordinary paper is used instead of thick filter paper, it may become alkaline after being soaked with water and contain a large amount of inorganic ions, which will have a great influence on the preservation and activity of the drug. pH value requirement: the pH value of the drug sensitivity paper sheet is generally required to be neutral to maintain the activity of the drug. If the pH value is not appropriate, it may affect the activity of the drug and the result of the drug sensitivity test. Thickness and diameter influence: the thickness of the drug sensitivity paper sheet is required to be about 1 mm to facilitate the growth of bacteria and the diffusion speed of the drug. The diameter of the paper sheet is between 6.00-6.35 mm, and these physical parameters will affect the result of the drug sensitivity test. Preservation condition: the preservation condition of the drug sensitivity paper sheet is crucial to its stability. For example, penicillin paper sheets are easily affected by a humid environment during preservation and reduce the activity of the drug, so they need to be preserved at low temperature and avoid moisture to maintain the activity of the antibacterial drug. Inter-sheet difference and accuracy: there may be a problem of too large or too small inhibition ring when the drug sensitivity paper sheet is purchased, and there is a great inter-sheet difference between the paper sheets. This requires that the inter-sheet difference and accuracy be checked before use, and only when the standard requirements are met can it be used. Operation error: in actual operation, if the drug sensitivity paper sheet is placed improperly, such as being placed in the central part of the culture medium instead of being uniformly arranged on the culture medium around the flat plate, it will also affect the result of the drug sensitivity test. Environmental factors: uneven distribution of temperature and humidity inside the test box may cause differences in stability between samples, affecting the stability of the drug sensitivity paper sheet. These shortcomings may lead to inaccurate results of the drug sensitivity test and affect the reliability of the antibiotic sensitivity test. Therefore, in order to improve the stability and accuracy of the drug sensitivity test paper disc, the design and use conditions of the test paper disc need to be optimized, including selecting appropriate materials, controlling pH value, ensuring that the physical parameters of the paper sheet are appropriate, strictly preserving the condition and standardizing the operation process. Practical new type content

[0004] The purpose of the present application is to provide a drug sensitivity test paper disc, which aims to solve the problems raised in the background art.

[0005] A drug sensitivity test paper disc, characterized in that it comprises,

[0006] A shell;

[0007] The fixed clamping assembly is arranged at the inside of the shell, wherein: the fixed clamping assembly comprises a fixed block, a moving plate, a moving shaft, a tooth groove, a first limiting block, a second limiting block, a spring, a fixed disc, a rotating shaft, a fixed bevel block, a first limiting groove, a second limiting groove and a third limiting groove, the fixed block is fixedly arranged at the bottom of the inner wall of the shell, the moving plate is slidingly connected to the upper portion of the outer wall of the fixed block, the moving shaft is fixedly arranged at the center of the bottom of the moving plate, the first limiting block is fixedly arranged at the bottom of the moving plate, the second limiting block is fixedly arranged at the bottom of the outer wall of the moving plate, the first limiting groove is arranged at the upper portion of the outer wall of the fixed block, the second limiting groove is arranged at the center of the outer wall of the fixed block, the third limiting groove is arranged at the upper portion of the outer wall of the fixed block, the tooth groove is arranged at the lower surface of the moving shaft, the first limiting block is slidingly connected to the inner wall of the first limiting groove, the second limiting block is slidingly connected to the inner wall of the third limiting groove, the spring is wound on the outer wall of the rotating shaft, the rotating shaft is rotatably connected to the outer wall of the moving plate, the fixed disc is fixedly arranged at the upper portion of the outer wall of the rotating shaft, and the fixed bevel block is fixedly arranged at the bottom of the outer wall of the rotating shaft.

[0008] Further, the outer portion of the fixed block is fixedly provided with a baffle, the outer portion of the baffle is fixedly provided with a motor, and the output end of the motor is fixedly provided with a gear.

[0009] Further, the gear and the tooth groove are in meshing connection.

[0010] Further, one end of the fixed bevel block and one end of the fixed block are matched with each other.

[0011] Further, the bottom of the fixed bevel block is sprayed with a rubber layer.

[0012] Further, the outer wall of the shell is sleeved with a sealing cover.

[0013] Compared with the prior art, the beneficial effects of the utility model are:

[0014] By starting the fixed clamping assembly, the two fixed bevel blocks can be used to fix the test paper, so that the stability of the test paper is not affected by external factors, the accuracy of the drug sensitivity test result is ensured, and the test paper can be conveniently released by the elasticity of the spring and the interaction between the fixed bevel block and the fixed block. BRIEF DESCRIPTION OF DRAWINGS

[0015] The drawings are used to provide a further understanding of the utility model, and constitute a part of the specification, are used together with the embodiments of the utility model to explain the utility model, and do not constitute the limitation to the utility model.

[0016] Figure 1 It is a perspective view of the utility model.

[0017] Figure 2 Part of the utility model for the development of the perspective view;

[0018] Figure 3 For the utility model Figure 2 A part of the enlarged view;

[0019] Figure 4 For the utility model Figure 2 B part of the enlarged view.

[0020] In the figure: 1, the shell;2, fixed block;3, moving plate;4, moving shaft;5, tooth groove;6, first limit block;7, second limit block;8, spring;9, fixed disc;10, rotating shaft;11, fixed chamfered block;12, first limit slot;13, second limit slot;14, third limit slot;15, baffle;16, motor;17, gear. Specific implementation

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0022] In the description of the utility model, it should be pointed out that the terms "upper", "lower", "inner", "outer", "top / bottom end" and the like indicate the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, therefore it cannot be understood as a limitation on the utility model. In addition, the terms "first", "second" are only for the purpose of description, and cannot be understood as indicating or implying relative importance.

[0023] In the description of the utility model, it should be pointed out that unless otherwise specified and limited, the terms "mounting", "provided with", "sleeved / connected", "connected" and the like should be understood broadly, for example, "connected" can be fixedly connected, or can be detachably connected, or integrally connected;It can be mechanical connection, or electrical connection;It can be directly connected, or indirectly connected through an intermediate medium, or the internal communication of two elements. For those skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0024] Please refer to Figures 1-4 The technical scheme provided by the embodiment is as follows:

[0025] A drug sensitivity detection test paper disc comprises,

[0026] The shell 1;

[0027] The fixed clamping assembly is arranged at the inside of the shell 1, wherein the fixed clamping assembly comprises a fixed block 2, a moving plate 3, a moving shaft 4, a tooth groove 5, a first limiting block 6, a second limiting block 7, a spring 8, a fixed disc 9, a rotating shaft 10, a fixed bevel block 11, a first limiting groove 12, a second limiting groove 13 and a third limiting groove 14, the fixed block 2 is fixedly arranged at the bottom of the inner wall of the shell 1, the moving plate 3 is slidingly connected to the upper part of the outer wall of the fixed block 2, the moving shaft 4 is fixedly arranged at the bottom center of the moving plate 3, the first limiting block 6 is fixedly arranged at the bottom of the moving plate 3, the second limiting block 7 is fixedly arranged at the bottom of the outer wall of the moving plate 3, the first limiting groove 12 is formed in the upper part of the outer wall of the fixed block 2, the second limiting groove 13 is formed in the center of the outer wall of the fixed block 2, the third limiting groove 14 is formed in the upper part of the outer wall of the fixed block 2, the tooth groove 5 is formed in the lower surface of the moving shaft 4, the first limiting block 6 is slidingly connected to the inner wall of the first limiting groove 12, the second limiting block 7 is slidingly connected to the inner wall of the third limiting groove 14, the spring 8 is wound around the outer wall of the rotating shaft 10, the rotating shaft 10 is rotationally connected to the outer wall of the moving plate 3, the fixed disc 9 is fixedly arranged at the upper part of the outer wall of the rotating shaft 10, and the fixed bevel block 11 is fixedly arranged at the bottom of the outer wall of the rotating shaft 10.

[0028] In the specific embodiment of the utility model, through starting the fixed clamping assembly, two fixed bevel blocks 11 can be fixed to test paper, so that the stability of the test paper is not affected by external factors, the accuracy of the drug sensitivity test result is ensured, and the test paper is more convenient to fix through the elasticity of the spring 8 and the interaction between the fixed bevel block 11 and the fixed block 2. When the fixed bevel block 11 gradually leaves the fixed block 2, the interaction force between the two surfaces of the fixed block 2 and the fixed bevel block 11 decreases, the spring 8 fixed on the moving plate 3 gradually relaxes, the rotating shaft 10 gradually rotates downwards, the fixed bevel block 11 stably contacts the test paper, and the fixing of the test paper is completed.

[0029] Specifically, the outer part of the fixed block 2 is fixedly provided with a baffle 15, the outer part of the baffle 15 is fixedly provided with a motor 16, and the output end of the motor 16 is fixedly provided with a gear 17.

[0030] In the specific embodiment of the utility model, the motor 16 drives the gear 17 to rotate.

[0031] Specifically, the gear 17 is in meshing connection with the tooth groove 5.

[0032] In the specific embodiment of the utility model, the gear 17 drives the moving shaft 4 with the tooth groove 5 to move forward and backward.

[0033] Specifically, one end of the fixed bevel block 11 and one end of the fixed block 2 match each other.

[0034] In the specific embodiment of the utility model, under the interaction of fixed bevel block 11 and fixed block 2, it is more convenient to fix the test paper.

[0035] Specifically, the bottom of the fixed bevel block 11 is sprayed with a rubber layer.

[0036] In the specific embodiment of the utility model, the bottom of the fixed bevel block 11 is sprayed with a rubber layer, so that the fixed bevel block 11 is more stable when fixing the test paper.

[0037] Specifically, the outer wall of the shell 1 is sleeved with a sealing cover.

[0038] In the specific embodiment of the utility model, the outer wall of the shell 1 is sleeved with a sealing cover, reducing the influence of external factors, so that the test data is more accurate.

[0039] Working principle:

[0040] By starting the fixed clamping assembly, the two fixed bevel blocks 11 can fix the test paper in front and back, avoid affecting the stability of the test paper due to external factors, ensure the accuracy of the drug sensitivity test result, and through the elasticity of the spring 8, under the interaction of the fixed bevel block 11 and the fixed block 2, it is more convenient to fix and release the test paper. First, start the motor 16 to drive the gear 17 to rotate, the gear 17 drives the moving shaft 4 with the toothed groove 5 to move forward and backward, when the fixed bevel block 11 gradually leaves the fixed block 2, the interaction force between the two faces of the fixed block 2 and the fixed bevel block 11 decreases, the spring 8 fixed on the moving plate 3 gradually relaxes, the rotating shaft 10 gradually rotates downward, so that the fixed bevel block 11 stably contacts the test paper, at this time, the fixing of the test paper is completed.

[0041] Finally, it should be noted that: the above only for the preferred embodiment of the utility model, and not for limiting the utility model, although the utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it still can modify the technical scheme recorded in the foregoing embodiments, or make equivalent replacement to part of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the utility model, should be included in the protection scope of the utility model.

Claims

1. A drug sensitivity test paper tray, characterized in that: include, Housing (1); A fixed clamping assembly is arranged inside the housing (1), wherein: the fixed clamping assembly includes a fixed block (2), a movable plate (3), a movable shaft (4), a tooth groove (5), a first limit block (6), a second limit block (7), a spring (8), a fixed disk (9), a rotating shaft (10), a fixed bevel block (11), a first limit groove (12), a second limit groove (13) and a third limit groove (14); the fixed block (2) is fixedly arranged at the bottom of the inner wall of the housing (1); the movable plate (3) is slidably connected to the upper part of the outer wall of the fixed block (2); the movable shaft (4) is fixedly arranged at the bottom center of the movable plate (3); the first limit block (6) is fixedly arranged at the bottom of the movable plate (3); the second limit block (7) is fixedly arranged at the bottom of the outer wall of the movable plate (3); The first limiting groove (12) is provided at the upper part of the outer wall of the fixed block (2), the second limiting groove (13) is provided at the center of the outer wall of the fixed block (2), the third limiting groove (14) is provided at the upper part of the outer wall of the fixed block (2), the tooth groove (5) is provided at the lower surface of the movable shaft (4), the first limiting block (6) is slidably connected to the inner wall of the first limiting groove (12), the second limiting block (7) is slidably connected to the inner wall of the third limiting groove (14), the spring (8) is wound around the outer wall of the rotating shaft (10), the rotating shaft (10) is rotatably connected to the outer wall of the movable plate (3), the fixed disk (9) is fixedly arranged at the upper part of the outer wall of the rotating shaft (10), and the fixed bevel block (11) is fixedly arranged at the bottom of the outer wall of the rotating shaft (10).

2. A drug sensitivity test paper tray according to claim 1, characterized in that: A baffle (15) is fixedly provided on the outside of the fixed block (2), a motor (16) is fixedly provided on the outside of the baffle (15), and a gear (17) is fixedly provided at the output end of the motor (16).

3. A drug sensitivity test paper tray according to claim 2, characterized in that: The gear (17) is meshingly connected with the tooth groove (5).

4. A drug sensitivity test paper tray according to claim 3, characterized in that: One end of the fixed bevel block (11) and one end of the fixed block (2) match each other.

5. A drug sensitivity test paper tray according to claim 4, characterized in that: The bottom of the fixed bevel block (11) is sprayed with a rubber layer.

6. A drug sensitivity test paper tray according to claim 5, characterized in that: The outer wall of the housing (1) is provided with a sealing cover.

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